Journal of Indian Society of Periodontology最新文献_第9页

Indian Society of Periodontology Scientific Events. 印度牙周病科学事件学会。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_558_25

引用次数: 0

Porous Ti6Al4V with controlled oxidation toward improved osseointegration of dental implant. 多孔Ti6Al4V控制氧化对牙种植体骨整合的改善。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_148_25

Rajashree Ganguly, Samir Das, Sundeep Venkata Sussela, Pravin Vasudeo Vaidya, Nantu Dogra, Tamal Kanti Pal, Madhumita Majumdar, Santanu Dhara

{"title":"Porous Ti6Al4V with controlled oxidation toward improved osseointegration of dental implant.","authors":"Rajashree Ganguly, Samir Das, Sundeep Venkata Sussela, Pravin Vasudeo Vaidya, Nantu Dogra, Tamal Kanti Pal, Madhumita Majumdar, Santanu Dhara","doi":"10.4103/jisp.jisp_148_25","DOIUrl":"10.4103/jisp.jisp_148_25","url":null,"abstract":"Background: Titanium (Ti) implants are known to be bioinert, stress shielding, and poor osseointegration, due to modulus discrepancy with native bone. This research aims to design a porous Ti6Al4V implant with controllable oxidation to mimic the natural bone properties for better osseointegration.Materials and methods: Porous Ti6Al4V foams were manufactured by coagulant-assisted metal foaming with egg white protein and citric acid as stabilizing matrix. The detailed characterization was conducted using X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, nanoindentation, and microcomputed tomography (micro-CT) to characterize microstructural, porosity, and mechanical properties. MTT assay and dual staining were used to study in vitro cytocompatibility using the human amniotic mesenchymal stem cells. In vivo biocompatibility and bone regeneration were evaluated through the rabbit femoral defect model at 4 and 12 weeks, using histology and micro-CT for bone ingrowth quantification.Results: The fabricated porous Ti6Al4V implants had 71%-75% porosity, facilitating nutrient transport and cellular ingrowth. Compressive modulus (284 MPa), measured via mechanical testing, was comparable to that of trabecular bone. In vitro studies demonstrated good cell viability and proliferation. In vivo, robust new bone formation was observed (~52% increase in bone volume), with over 90% tissue integration compared to control.Conclusions: Controlled oxidation of porous Ti6Al4V foam could provide a potential way to overcome the current limitations of dental implants. The improved biomechanical compatibility and osseointegration support its potential for clinical application in implantology.","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"29 5","pages":"537-547"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12736681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frozen advanced platelet-rich fibrin as an adjunct to the modified tunnel technique for root coverage: A pilot randomised clinical trial. 冷冻晚期富血小板纤维蛋白作为改良隧道技术根根覆盖的辅助手段：一项先导随机临床试验。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_419_24

Sruthima N V S Gottumukkala, Murali Krishna, Gautami S Penmetsa, K S V Ramesh, P Mohan Kumar, Anusha Boddeda, Bhavya Manchala

{"title":"Frozen advanced platelet-rich fibrin as an adjunct to the modified tunnel technique for root coverage: A pilot randomised clinical trial.","authors":"Sruthima N V S Gottumukkala, Murali Krishna, Gautami S Penmetsa, K S V Ramesh, P Mohan Kumar, Anusha Boddeda, Bhavya Manchala","doi":"10.4103/jisp.jisp_419_24","DOIUrl":"10.4103/jisp.jisp_419_24","url":null,"abstract":"Background: Platelet-rich fibrin (PRF) is a widely used second-generation blood concentrate in periodontal regeneration. It has a few disadvantages, such as the fragile nature of the membrane, difficulty in suturing, and unpredictability of outcomes. The present study aims to evaluate the clinical outcomes, healing, and postoperative morbidity following the use of frozen advanced PRF (-20°C for 24 h) with modified coronally advanced tunnel (MCAT) technique in the treatment of multiple adjacent recession defects (MARDs).Materials and methods: This is a prospective, split-mouth, randomized controlled clinical trial including 42 teeth with bilateral MARD in 10 participants. Sites were randomized to frozen (Fz-PRF) and fresh advanced PRF (A-PRF) groups and treated with Fz-PRF using MCAT and A-PRF using MCAT, respectively. Root coverage parameters (recession depth [RD], recession width [RW], complete root coverage, percentage root coverage [%RC], mechanical characteristics [needle passage ease, surgical handling of the membrane, and membrane fraying], postoperative healing [Wachtel's Healing Index], and patient-reported outcomes [discomfort and esthetic satisfaction]) were assessed.Results: Mean %RC (P = 0.025), RW (0.044), mechanical characteristics (P = 0.000), and esthetic satisfaction (P = 0.015) were significantly better in the Fz-PRF group. No significant variation was observed in patient discomfort and postoperative healing.Conclusions: Fz-PRF showed better root coverage, mechanical properties, and esthetic satisfaction than A-PRF; as a result, it might be an effective alternative to conventional methods of treating gingival recessions.","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"29 5","pages":"514-521"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12736668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immediate implant placement in a chronic periradicular resorptive lesion: A case report of timely restoration and successful outcomes. 慢性根周吸收性病变即刻种植：及时修复和成功结果的一例报告。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_87_25

Manish Rathi, Saravanan Sampoornam Pape Reddy, Tomas Linkevicius

{"title":"Immediate implant placement in a chronic periradicular resorptive lesion: A case report of timely restoration and successful outcomes.","authors":"Manish Rathi, Saravanan Sampoornam Pape Reddy, Tomas Linkevicius","doi":"10.4103/jisp.jisp_87_25","DOIUrl":"10.4103/jisp.jisp_87_25","url":null,"abstract":"This case report presents the case of a 34-year-old male with a chronic periradicular abscess, fractured prosthesis, and significant mandibular bone resorption. The goal was to restore function and esthetics through immediate implant placement (IIP) despite infection and bone loss. Examination revealed Grade III mobility of teeth #19 and #20, a draining sinus, and extensive bone resorption confirmed by the cone-beam computed tomography. Using the Simple, Advanced, Complex classification, the case was classified into \"complex\" due to its pathology and poor bone quality. IIP was chosen after careful debridement and bone grafting with xenogeneic material. The implants were placed with primary stability, and a customized healing abutment was prepared for optimal soft-tissue healing. This case shows that IIP is effective in challenging conditions with infection and bone resorption, given careful planning, infection control, and grafting. Treatment was successful with long-term outcomes. Bone healing and implant integration were confirmed at follow-up, providing functional and esthetic restorations.","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"29 5","pages":"560-565"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12736676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of hyaluronic acid on the inhibition of periodontal bridging organisms Fusobacterium nucleatum and Prevotella intermedia: An in vitro study. 透明质酸对牙周桥接菌核梭杆菌和中间普氏菌抑制作用的体外研究。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_278_25

Sanjeevini Hattarki, Sandeep S Katti, K V Madhushree, Vaishali Rathod, Shivani Kadam, Anisha Jose

{"title":"Efficacy of hyaluronic acid on the inhibition of periodontal bridging organisms Fusobacterium nucleatum and Prevotella intermedia: An in vitro study.","authors":"Sanjeevini Hattarki, Sandeep S Katti, K V Madhushree, Vaishali Rathod, Shivani Kadam, Anisha Jose","doi":"10.4103/jisp.jisp_278_25","DOIUrl":"10.4103/jisp.jisp_278_25","url":null,"abstract":"Objective: This in vitro study aimed to evaluate the antimicrobial effects of high-molecular-weight hyaluronic acid (HA) against two key periodontal bacteria, Prevotella intermedia and Fusobacterium nucleatum. These organisms play an important role in biofilm formation and disease progression in periodontitis.Materials and methods: Standard laboratory strains of P. intermedia (ATCC 25611) and F. nucleatum (ATCC 25568) were cultured in anaerobic conditions. HA with different molecular weights (141 kDa, 757 kDa, and 1,300 kDa) was tested at concentrations from 0.5 to 2.0 mg/ml. The minimum inhibitory concentration was determined through serial dilution in thioglycollate broth. Each test was performed in triplicate. Turbidity after 48-72 h of incubation served as an indicator of bacterial growth. Statistical significance was analyzed using G*Power with α = 0.05 and 80% power.Results: HA showed concentration-dependent bacteriostatic effects. P. intermedia showed growth inhibition at 1 mg/ml, whereas F. nucleatum required 2 mg/ml for similar inhibition. Concentrations below these amounts did not inhibit growth. These findings suggest that HA may disrupt adhesion and nutrient uptake needed for bacterial growth and biofilm formation.Conclusion: High-molecular-weight HA shows potential as a nonantibiotic support agent in periodontal therapy by selectively inhibiting key anaerobic bacteria involved in biofilm development. Its two actions, antimicrobial and immunomodulatory, highlight its importance by breaking down pathogenic cooperation and supporting periodontal healing. Further research with multispecies biofilms, clinical isolates, and host interaction models is necessary for clinical application.","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"29 5","pages":"548-552"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12736737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative evaluation of coronally positioned flap with prereacted glass ionomer (Giomer) and zirconia-reinfused glass ionomer (Zirconomer) in the treatment of gingival recession incidental with non-carious cervical lesions: A randomized clinical trial. 冠状定位玻璃离聚体（Giomer）与氧化锆再灌注玻璃离聚体（Zirconomer）瓣治疗伴非龋齿宫颈病变牙龈退缩的随机临床研究。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_238_23

Prakash Pai Gurpur, Devipriya B Nayanar, Mundoor Manjunath Dayakar, G Apoorva

{"title":"Comparative evaluation of coronally positioned flap with prereacted glass ionomer (Giomer) and zirconia-reinfused glass ionomer (Zirconomer) in the treatment of gingival recession incidental with non-carious cervical lesions: A randomized clinical trial.","authors":"Prakash Pai Gurpur, Devipriya B Nayanar, Mundoor Manjunath Dayakar, G Apoorva","doi":"10.4103/jisp.jisp_238_23","DOIUrl":"10.4103/jisp.jisp_238_23","url":null,"abstract":"Aim: The study compared the clinical effectiveness of Giomer and Zirconomer in patients with gingival recession (GR) associated with noncarious cervical lesions (NCCLs), and evaluated their outcomes when combined with coronally advanced flap (CAF).Materials and methods: Nine subjects with bilateral Cairo et al. recession type 1 associated with NCCL suggestive of CAF with restorations underwent a split-mouth randomized clinical trial. Eighteen sites were randomly assigned to one of the two groups and restored using Zirconomer (Group A) or Giomer (Group B). CAF was performed after 2 weeks, and patients were followed up at 3 and 6 months. Plaque index (PI), gingival bleeding index (GBI), pocket depth (PD), relative GR (RGR), clinical attachment level (CAL), height of NCCL (NCCL-H), thickness (KTT), and width (KTW) of keratinized tissue and dentinal hypersensitivity (DH) were recorded at baseline, 3, and 6 months postsurgery.Results: Both groups revealed excellent root coverage and CAL gain, although Group A significantly had higher KTW than Group B. After 6 months, the PI, PD, CAL, RGR, and KTW displayed statistically notable variations between the groups. At 6 months, Group A displayed better relief in DH as well as improved RGR and CAL.Conclusion: Both Zirconomer and Giomer, coupled with CAF, achieved sufficient soft-tissue coverage after 6 months. The Zirconomer group, however, had marginally better outcomes in terms of PI, RGR, NCCL-H, KTW, and DH, while Giomer performed better in terms of PD and CAL.","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"29 5","pages":"482-488"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12736685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevating standards, elevating minds: The way forward for periodontal teaching in India. 提升标准，提升思想：印度牙周教学的前进之路。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_542_25

Ashish Jain

引用次数: 0

Evaluation and comparison of semaphorin 4D levels in saliva of periodontally healthy and Stage 1 Grade A periodontitis patients and its response to nonsurgical periodontal treatment: A clinicobiochemical interventional study. 牙周健康与1期A级牙周炎患者唾液中信号素4D水平的评价与比较及其对牙周非手术治疗的反应：临床生化介入研究

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_413_24

Bela Nagasmal Khobragade, Dipika Mitra, Ankita Rajesh Mishra, Saurabh Prithyani, Neha Bipin Surve

{"title":"Evaluation and comparison of semaphorin 4D levels in saliva of periodontally healthy and Stage 1 Grade A periodontitis patients and its response to nonsurgical periodontal treatment: A clinicobiochemical interventional study.","authors":"Bela Nagasmal Khobragade, Dipika Mitra, Ankita Rajesh Mishra, Saurabh Prithyani, Neha Bipin Surve","doi":"10.4103/jisp.jisp_413_24","DOIUrl":"10.4103/jisp.jisp_413_24","url":null,"abstract":"Background: Salivary biomarkers have the potential to be used as diagnostic tools for periodontal disease. This study aimed to evaluate the role of semaphorin 4D (SEMA4D) in saliva among healthy and periodontitis subjects and its response to nonsurgical periodontal treatment.Materials and methods: An interventional clinicobiochemical study was conducted on the study population. SEMA4D levels were evaluated and compared using enzyme-linked immunosorbent assay (ELISA). Individuals with periodontitis underwent nonsurgical treatment followed by ELISA.Statistical analysis: Intergroup comparison was performed using one-way analysis of variance to assess significant differences between the groups, followed by post hoc Tukey's test. Intragroup comparison was performed using a paired t-test to assess significant differences. Pearson's correlation coefficient helped to determine the strength of association.Results: Increased levels of SEMA4D were seen in subjects with Stage 1 Grade A periodontitis. Correlation of SEMA4D to the gingival index, clinical attachment loss, and probing pocket depth was not statistically significant.Conclusion: SEMA4D can be a potential biomarker since there is a positive relation between SEMA4D and Stage 1 Grade A periodontitis.","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"29 5","pages":"477-481"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12736736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the efficacy of autogenous bone graft in combination with hydroxyapatite and beta-tricalcium phosphate in direct sinus augmentation - A clinical, radiographic, and histologic study. 自体骨移植物联合羟基磷灰石和β -磷酸三钙直接窦内增强的疗效评价——一项临床、影像学和组织学研究。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_30_25

Jaya Nathani, Shaleen Khetarpal, Madhu Singh Ratre, Satyajit Ashok Tekade, Manish Verma

{"title":"Evaluation of the efficacy of autogenous bone graft in combination with hydroxyapatite and beta-tricalcium phosphate in direct sinus augmentation - A clinical, radiographic, and histologic study.","authors":"Jaya Nathani, Shaleen Khetarpal, Madhu Singh Ratre, Satyajit Ashok Tekade, Manish Verma","doi":"10.4103/jisp.jisp_30_25","DOIUrl":"10.4103/jisp.jisp_30_25","url":null,"abstract":"Background: Maxillary sinus augmentation is a predictable procedure to increase bone height in atrophic posterior maxilla. Different protocols and procedures for sinus lift are available. Many biomaterials are employed in this technique; however, no biomaterial has been proven as the best.Materials and methods: A single-center, prospective, interventional, single-arm study was done for evaluation of the efficacy of biphasic calcium phosphate mixed in a 1:1 ratio with autogenous bone graft. Patients with ≤5 mm of subantral bone height were recruited. Sinus membrane was elevated using piezosurgical tips and sinus elevators, and a graft was placed to achieve the desired bone height. Lateral window was covered by platelet-rich fibrin membrane, and suturing was done. After 6 months, bone biopsy specimens were harvested, and histomorphometric analysis was performed. Subantral bone height was measured on cone-beam computed tomography at baseline and at 6 months to get the bone height gain.Results: (1) The mean gain of bone height was 8.53 ± 1.07 which was statistically significant. (2) On histologic evaluation, new bone% was 48.08% ± 2.41%, soft tissue% was 27.25% ± 3.18%, and residual graft% was 24.36% ± 2.91%. (3) The density and distribution of cells were favorable. (4) All patients had pain and swelling in mild range. (5) No major intra- or postoperative complications were noted.Conclusion: The described surgical technique using a combination of hydroxyapatite + beta-tricalcium phosphate 30/70 along with autogenous bone in a 1:1 ratio offers a predictable and practical treatment choice in direct sinus augmentation. It provided significant bone height gain, new bone formation, and good implant stability in grafted sites.","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"29 5","pages":"529-536"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12736675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From etiology to intervention: 50 years of progress in gummy smile research and treatment. 从病因到干预：软性微笑研究和治疗的50年进展。

Journal of Indian Society of Periodontology Pub Date : 2025-09-01 Epub Date: 2025-12-17 DOI: 10.4103/jisp.jisp_548_25

Dimitris N Tatakis

{"title":"From etiology to intervention: 50 years of progress in gummy smile research and treatment.","authors":"Dimitris N Tatakis","doi":"10.4103/jisp.jisp_548_25","DOIUrl":"10.4103/jisp.jisp_548_25","url":null,"abstract":"Excessive gingival display, commonly referred to as a \"gummy smile,\" is defined as more than 3 mm of gingival exposure during smiling and is often perceived as unesthetic, potentially leading to psychological and social concerns for affected individuals. Over the past five decades, significant progress has been made in understanding the etiology, diagnosis, and treatment of this condition. Initially regarded as a functional or developmental issue, the gummy smile has evolved into a major esthetic concern, reflected in the exponential growth of related scientific literature. Early treatment approaches (1975-2000) focused on surgical interventions such as orthognathic surgery, lip repositioning, and gingival reduction procedures, alongside foundational diagnostic classifications. In the last two decades (2001-2025), advancements have included refinements in surgical techniques, incorporation of digital workflows, and introduction of minimally invasive and nonsurgical options. Recent research emphasizes patient-reported outcomes, esthetic assessments, and algorithm-based treatment planning, while emerging technologies promise further improvements in diagnosis and personalized care. Continued innovation and interdisciplinary collaboration are essential to optimize treatment strategies and enhance patient satisfaction.","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"29 5","pages":"463-465"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12736691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0