Journal of Indian Society of Periodontology最新文献

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Ten-year prognostic outcomes of molar survival using the Miller-Mcentire Periodontal Prognostic Index - A longitudinal prospective study. 使用米勒-曼蒂尔牙周预后指数(Miller-Mcentire Periodontal Prognostic Index)得出的臼齿存活十年预后结果--一项纵向前瞻性研究。
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_542_23
Dharmarajan Gopalakrishnan, Preston Dallas Miller, Robert A Levine, Sangamithra Sidharthan, Amit Vasant Mahuli, Muhammad H A Saleh, Whitney Miller, Borvornwut Buranawat
{"title":"Ten-year prognostic outcomes of molar survival using the Miller-Mcentire Periodontal Prognostic Index - A longitudinal prospective study.","authors":"Dharmarajan Gopalakrishnan, Preston Dallas Miller, Robert A Levine, Sangamithra Sidharthan, Amit Vasant Mahuli, Muhammad H A Saleh, Whitney Miller, Borvornwut Buranawat","doi":"10.4103/jisp.jisp_542_23","DOIUrl":"10.4103/jisp.jisp_542_23","url":null,"abstract":"<p><strong>Background: </strong>A 10-year survival analysis was performed to assess the predictive validity of the periodontal risk score (formerly known as Miller-McEntire Periodontal Prognostic Index [MMPPI]) to predict long-term survival of periodontally diseased molars in a longitudinally assessed cohort.</p><p><strong>Materials and methods: </strong>The MMPPI scores were computed at baseline by summarizing scores allocated for individual factors. The cohort was treated, followed up, and placed under regular periodontal maintenance. Molar survival data collected up to 10 years of follow-up were analyzed. Cox proportional regression was performed, and hazards ratio (HR) were computed for each prognostic factor and the MMPPI score. To estimate the predictive value of MMPPI, a receiver operating curve (ROC) curve analysis was performed.</p><p><strong>Results: </strong>From 1032 molars, 155 molars were extracted over the 10-year follow-up duration. Cox proportional hazard analysis showed significant hazard ratios for tooth loss for the component variables significant HR was noted for age: 4.92 (3.34:7.27), smoking: 1.74 (1.38-2.22), diabetes: 1.66 (1.49-1.86), molar type: 1.39 (1.15-1.67), probing depth: 2.00 (1.63-2.46), furcation: 2.64 (2.30-3.03), mobility: 3.45 (2.98-4.01), and total MMPPI score: 1.98 (1.85-2.12). ROC curve analysis showed an area under the curve value of 0.94 for the MMPPI index as a predictor of molar loss at 8 years, and the Youden index was maximized at the optimal cutoff point score of 7.</p><p><strong>Conclusions: </strong>All component scores of MMPPI showed significant hazard ratios at 10 years. These findings support the previous results from the 5-year analysis of this university-based cohort and warrant validation in independent cohorts.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of loop-mediated isothermal amplification method for efficient detection of the periodontopathic bacteria Porphyromonas gingivalis. 评估环介导等温扩增法在有效检测牙周病病菌牙龈卟啉单胞菌方面的应用。
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_260_23
Meenaz N Sangolli, Manohar S Kugaji, Suman Kumar Ray, Kishore G Bhat
{"title":"Evaluation of loop-mediated isothermal amplification method for efficient detection of the periodontopathic bacteria <i>Porphyromonas gingivalis</i>.","authors":"Meenaz N Sangolli, Manohar S Kugaji, Suman Kumar Ray, Kishore G Bhat","doi":"10.4103/jisp.jisp_260_23","DOIUrl":"10.4103/jisp.jisp_260_23","url":null,"abstract":"<p><strong>Background: </strong>Periodontitis is a multifactorial, polymicrobial oral inflammatory illness brought on by oral pathogens. <i>Porphyromonas</i> <i>gingivalis</i> is a Gram-negative, obligatory anaerobic, black-pigmented coccobacillus and is regarded as a primary etiological factor in the progression of periodontitis. Rapid, highly senstitive and specific detection methods are emerging. The present study aimed to evaluate the loop-mediated isothermal amplification (LAMP) technique for efficiently detecting <i>P</i>. <i>gingivalis</i> from subgingival plaque samples of chronic periodontitis patients.</p><p><strong>Materials and methods: </strong>This study included 50 subgingival plaque samples from patients suffering from chronic periodontitis. The DNA (Deoxyribonucleic acid) was extracted by the \"modified proteinase K\" method. A set of six primers, targeting the <i>pepO</i> gene of <i>P</i>. <i>gingivalis</i>, was used for conducting LAMP. The amplification was visualized by naked-eye detection and agarose electrophoresis. Conventional polymerase chain reaction (PCR) and real-time qantitative PCR (qPCR) were carried out by targeting the 16SrRNA (16S ribosomal ribonucleic acid) gene of <i>P</i>. <i>gingivalis</i>.</p><p><strong>Results: </strong>The results showed that LAMP detected <i>P</i>. <i>gingivalis</i> in 40 out of 50 samples (80%). Whereas, qPCR and conventional PCR technique detected <i>P. gingivalis</i> in 38 (76%) and 33 (66%) samples respectively. The sensitivity and specificity of the LAMP method were 94.87% and 90.90%, respectively. With qPCR, the sensitivity and specificity were found to be 92.30% and 81.81%, respectively, whereas, with conventional PCR, it was found to be 76.92% and 72.72%, respectively.</p><p><strong>Conclusion: </strong>LAMP is an efficient technique for quick, accurate, and reliable identification of <i>P</i>. <i>gingivalis</i> from subgingival plaque samples. The technique needs to be validated analytically, and further studies can be conducted by taking saliva and/or gingival crevicular fluid samples from periodontitis patients.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Free gingival graft embossed over laterally flipped periosteum for root coverage: A novel case report. 在侧翻的骨膜上压印游离龈移植物以覆盖牙根:一份新颖的病例报告。
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_447_23
R Ambili, Devika Gopakumar, Basim Burhan Kurudamparambil Badarudhin
{"title":"Free gingival graft embossed over laterally flipped periosteum for root coverage: A novel case report.","authors":"R Ambili, Devika Gopakumar, Basim Burhan Kurudamparambil Badarudhin","doi":"10.4103/jisp.jisp_447_23","DOIUrl":"10.4103/jisp.jisp_447_23","url":null,"abstract":"<p><p>Innovations in surgical techniques have improved the esthetic outcome and predictability of root coverage procedures in recent years. A free gingival graft (FGG) augments the attached gingiva, but the compromised blood supply precludes its use in root coverage. In the surgical technique described in this case report, the FGG kept over a laterally placed periosteal flap enhanced the outcome. A laterally flipped periosteal flap was adapted over the root surface using resorbable sutures. The free graft was secured at the recipient site with cyanoacrylate adhesive, and adaptation was ensured with suspensory sutures. Satisfactory root coverage was appreciated and maintained at 6 months with excellent functional outcomes. Adequate width of the attached gingiva and vestibular depth were also noticed at the recipient site. The patient was highly satisfied with the obtained results, which were maintained until the 1-year postoperative period.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of hard and soft tissue parameters by using short implants and standard long implants with sinus lift for prosthetic rehabilitation of posterior maxilla. 使用短种植体和标准长种植体以及上颌窦提升术进行上颌后部修复,对硬组织和软组织参数进行比较评估。
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_436_23
Farhan Durrani, S M Karthickraj, Fouzia Imran, Shweta Ahlawat, Ekta Kumari, S U Gokila Vani
{"title":"Comparative evaluation of hard and soft tissue parameters by using short implants and standard long implants with sinus lift for prosthetic rehabilitation of posterior maxilla.","authors":"Farhan Durrani, S M Karthickraj, Fouzia Imran, Shweta Ahlawat, Ekta Kumari, S U Gokila Vani","doi":"10.4103/jisp.jisp_436_23","DOIUrl":"10.4103/jisp.jisp_436_23","url":null,"abstract":"<p><strong>Objective: </strong>The objective is to compare and evaluate the hard and soft tissue parameters by using short and standard long implants with sinus lifting in the posterior maxilla.</p><p><strong>Materials and methods: </strong>Eleven patients with complaints of missing upper back teeth were enrolled in the study for implant-supported rehabilitation and were categorized into two groups: Group long (GL): longer implant (>8 mm) placement, preceded by Sinus Augmentation. Group short (GS): short implant (≤8 mm) placement, without sinus augmentation. The primary outcome measured was cumulative survival rate (CSR) in the compromised partial edentulous posterior maxilla. Secondary outcomes measured were implant stability (IS), marginal bone level alterations (MBL), pocket probing depth (PPD), crown-to-implant ratio, and any complications.</p><p><strong>Results: </strong>The difference in CSR between the groups was not statistically significant (<i>P</i> = 0.317). High stability was achieved immediately after the placement of the implants, in both groups (GS: 64 ± 4.07, GL: 65.58 ± 9.75); this difference in the mean ISQ (IS quotients) values was not found to be statistically significant at implant placement (<i>P</i> = 0.7). The mean MBL reported in the study at the end of 12 months of prosthesis function was - 0.762 ± 0.48 mm and - 0.7 ± 0.34 mm for GS and GL, respectively. The mean PPD measurements in GS and GL groups were 1.917 ± 0.68 mm and 1.833 ± 0.38 mm, respectively, and it was not statistically significant (<i>P</i> = 0.8).</p><p><strong>Conclusion: </strong>Within the limitations of the present study, the obtained results indicate that short implants provided a similar clinical and radiographic performance compared to long implants placed in combination with a sinus augmentation procedure (lateral window) up to 12 months after prosthetic loading.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do patients deserve more information in deciding whether to extract their teeth or to maintain their teeth? 在决定拔牙还是保留牙齿时,患者是否应该获得更多信息?
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_86_24
Dharmarajan Gopalakrishnan
{"title":"Do patients deserve more information in deciding whether to extract their teeth or to maintain their teeth?","authors":"Dharmarajan Gopalakrishnan","doi":"10.4103/jisp.jisp_86_24","DOIUrl":"10.4103/jisp.jisp_86_24","url":null,"abstract":"","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Indian Society of Periodontology Good Clinical Practice Recommendations for Peri-implant Care. 印度牙周病学会关于种植体周围护理的良好临床实践建议。
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_124_24
Anurag Satpathy, Vishakha Grover, Ashish Kumar, Ashish Jain, Dharmarajan Gopalakrishnan, Harpreet Singh Grover, Abhay Kolte, Anil Melath, Manish Khatri, Nitin Dani, Roshani Thakur, Vaibhav Tiwari, Vikender Singh Yadav, Biju Thomas, Gurparkash Singh Chahal, Meenu Taneja Bhasin, Nymphea Pandit, Sandeep Anant Lawande, R G Shiva Manjunath, Surinder Sachdeva, Amit Bhardwaj, Avni Raju Pradeep, Ashish Sham Nichani, Baljeet Singh, P R Ganesh, Neeraj Chandrahas Deshpande, Saravanan Sampoornam Pape Reddy, Subash Chandra Raj
{"title":"Indian Society of Periodontology Good Clinical Practice Recommendations for Peri-implant Care.","authors":"Anurag Satpathy, Vishakha Grover, Ashish Kumar, Ashish Jain, Dharmarajan Gopalakrishnan, Harpreet Singh Grover, Abhay Kolte, Anil Melath, Manish Khatri, Nitin Dani, Roshani Thakur, Vaibhav Tiwari, Vikender Singh Yadav, Biju Thomas, Gurparkash Singh Chahal, Meenu Taneja Bhasin, Nymphea Pandit, Sandeep Anant Lawande, R G Shiva Manjunath, Surinder Sachdeva, Amit Bhardwaj, Avni Raju Pradeep, Ashish Sham Nichani, Baljeet Singh, P R Ganesh, Neeraj Chandrahas Deshpande, Saravanan Sampoornam Pape Reddy, Subash Chandra Raj","doi":"10.4103/jisp.jisp_124_24","DOIUrl":"10.4103/jisp.jisp_124_24","url":null,"abstract":"<p><p>Current implant therapy is a frequently employed treatment for individuals who have lost teeth, as it offers functional and biological advantages over old prostheses. Concurrently, active exploration of intervention strategies aims to prevent the progression of peri-implant diseases and manage the existing peri-implant tissue damage. Indian Society of Periodontology has recognized the need for systematic documents to update the everyday clinical practice of general dental practitioners and has provided evidence-based consensus documents, namely good clinical practice recommendations from time to time to raise the oral health-related awareness and standards of oral health-care delivery across the country. The current clinical practice recommendations focused on peri-implant care to bridge the gap between academic theory and clinical practice by compiling evidence-based suggestions for preventing and treating peri-implant diseases. Twenty-eight subject experts across the country prepared these recommendations after a thorough literature review and group discussions. The document has been prepared in three sections covering peri-implant health and maintenance, peri-implant mucositis, and peri-implantitis. It will be a quick and concise reference for oral implant practitioners in patient management. The guidelines provide distinct definitions, signs, and symptoms, treatment required; recall visit specifications for plausible clinical case situations, and home-care recommendations regarding maintaining peri-implant health. The document advocates combined efforts of oral implant practitioners and the population at large with evidence-based, integrated, and comprehensive peri-implant care. By providing accessible, applicable guidance, these guidelines would empower dental professionals to uphold the well-being of implant patients and ensure the long-term success of implant therapy.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammatory profile of patients with different weight diagnoses and similar periodontal condition: A systematic review. 体重诊断不同但牙周状况相似的患者的炎症特征:系统综述。
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_511_23
Juliana Dos Santos Feijo, Ana Flávia Leite Pontes, Taciane Menezes da Silveira, Natália Marcumini Pola, Francisco Wilker Mustafa Gomes Muniz
{"title":"Inflammatory profile of patients with different weight diagnoses and similar periodontal condition: A systematic review.","authors":"Juliana Dos Santos Feijo, Ana Flávia Leite Pontes, Taciane Menezes da Silveira, Natália Marcumini Pola, Francisco Wilker Mustafa Gomes Muniz","doi":"10.4103/jisp.jisp_511_23","DOIUrl":"10.4103/jisp.jisp_511_23","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to systematically review the literature regarding the inflammatory profiles, measured by cytokines and chemokines, of individuals with different diagnoses of weight, but with the similar periodontal condition.</p><p><strong>Materials and methods: </strong>Searches were performed in five databases (Scopus, EMBASE, PubMed, Web of Science, and Cochrane-Central). Studies that compared the inflammatory profile of normal-weight individuals to those with obesity and evaluated the same cytokine, collection method, and periodontal diagnosis (periodontal health, gingivitis, or periodontitis) were included. Cross-sectional studies underwent evaluation by independent researchers using the Joanna Briggs Institute Critical Appraisal Checklist. The GRADE (Grades of Recommendation, Assessment, Development and Evaluation) system assessed evidence certainty.</p><p><strong>Results: </strong>Twelve studies were included. The diagnosis of obesity was done on the basis of body mass index, waist circumference, and waist-hip ratio. Pro-inflammatory cytokines (interleukin-6 [IL-6], tumor necrosis factor-α [TNF]-α, IL-1β, IL-31, and IL-34) were analyzed in serum, saliva, gingival crevicular fluid (GCF), and plasma. Periodontal diagnoses varied across studies. TNF-α expression was significantly higher in individuals with obesity and periodontal health or periodontitis. Serum IL-1β levels showed mixed results, but salivary IL-1β levels were elevated in obese individuals. IL-6 levels were higher in obese individuals, regardless of periodontal status. IL-34 and IL-10 showed no significant differences across groups. Monocyte chemoattractant protein-4 (MCP-4) levels were higher in obese individuals with periodontitis or periodontal health. IL-31 and IL-34 in GCF showed no significant differences between obese and nonobese individuals, without periodontitis.</p><p><strong>Conclusions: </strong>Heterogeneous results were noted for IL-6, IL-1β, IL-31, IL-34, TNF-α, and MCP-4, hindering conclusions on weight's impact on inflammatory profiles in periodontal patients.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of bone apposition on surface modified titanium implant in experimental animal model: A systematic review and meta-analysis. 在实验动物模型中评估表面改性钛种植体的骨附着情况:系统回顾与荟萃分析。
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_222_22
Priya Saini, Shaveta Sood, Gurparkash Singh Chahal, Ashish Jain
{"title":"Evaluation of bone apposition on surface modified titanium implant in experimental animal model: A systematic review and meta-analysis.","authors":"Priya Saini, Shaveta Sood, Gurparkash Singh Chahal, Ashish Jain","doi":"10.4103/jisp.jisp_222_22","DOIUrl":"10.4103/jisp.jisp_222_22","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the response of peri-implant bone to smooth (machined) surface and surface-modified dental implants in healthy experimental animal models.</p><p><strong>Materials and methods: </strong>Systematic electronic search was done for using PUBMED, SCOPUS, WEB OF SCIENCE, and EMBASE databases for potentially relevant records from the last 20 years. Duplicate screening and data extraction were performed to formulate the evidence tables and meta-analysis following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The outcome criteria were: 1. Bone Implant Contact (BIC) in percentage, 2. Removal Torque Values (RTV) in Ncm, 3. Implant stability Quotient (ISQ), Quality assessment was done using the ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines and SYRCLE RoB (Systematic Review Centre for Laboratory Animal Experimentation Risk of Bias) tool.</p><p><strong>Results: </strong>Results were expressed as pooled mean difference for the respective groups viz. sandblasted and acid etched, laser modified, acid etched and anodized surface. The surface modified implants revealed somewhat higher BIC over machined surface (<i>P</i> < 0.01). Forest plot were drawn for all the outcome variables.</p><p><strong>Conclusions: </strong>Within the limitations of this study, the authors found a higher degree of osseointegration pertaining to bone to implant interface, RTV, and implant stability quotient (ISQ) with surface modified procedures which seemed to promote bone formation around peri-implant tissue during the early stages of healing. After analyzing all 37 included publications for the outcome of interest (BIC%, RTV, ISQ), a positive outcome was obtained for both subtractive and additive implant surface modifying procedures over machined implant surfaces when the data were pooled together. More advanced research work on healthy animal models needs to be investigated to review the impact of surface modifications on dental implant osseointegration.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression dynamics of microRNA-223/Ras-associated binding protein 12 axis in Stage III/Grade B periodontal disease: A case-control analysis. 微RNA-223/Ras相关结合蛋白12轴在III期/B级牙周病中的表达动态:病例对照分析
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_179_23
Dhathri Priya Bandi, Uma Sudhakar, Harinath Parthasarathy, Snophia Rani Rajamani, Balasubramanian Krishnaswamy
{"title":"Expression dynamics of microRNA-223/Ras-associated binding protein 12 axis in Stage III/Grade B periodontal disease: A case-control analysis.","authors":"Dhathri Priya Bandi, Uma Sudhakar, Harinath Parthasarathy, Snophia Rani Rajamani, Balasubramanian Krishnaswamy","doi":"10.4103/jisp.jisp_179_23","DOIUrl":"10.4103/jisp.jisp_179_23","url":null,"abstract":"<p><strong>Background: </strong>The intricate interplay between periodontal polymicrobial flora and an altered immune response is the central cause of periodontal disease. Multiple cell death methods and their interactions, along with the associated signaling pathways, significantly impact the initiation and advancement of periodontitis. Our speculation revolves around the role of the miR-223/Ras-associated binding protein (RAB12) signaling axis in regulating autophagy-induced pyroptosis, contributing to the pathophysiology of periodontitis. Thus, this study aimed to investigate miR-223 and RAB12 expression patterns in Stage III/Grade B periodontal disease.</p><p><strong>Materials and methods: </strong>The study included 50 healthy individuals and 50 patients diagnosed with Stage III/Grade B periodontal disease. Clinical parameters were cataloged for each participant. miRNA-223 underwent an <i>in silico</i> analysis to identify its potential target genes. Gingival crevicular fluid (GCF) samples were collected from the subjects for real-time polymerase chain reaction to evaluate the expression of both miR-223 and the RAB12 gene.</p><p><strong>Results: </strong>The miRTargetLink2.0 analysis highlighted the RAB12 gene as a prime target for miR-223. In periodontal disease patients, miR-223 and RAB12 gene expressions significantly increased (15.21 and 34.70-fold changes, respectively; <i>P</i> < 0.05). Receiver operating characteristic analysis suggested that miR-223 is a potential biomarker for periodontal disease, with 76% diagnostic accuracy and an area under the curve of 0.777 (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>MicroRNA-223 and its target gene RAB12 exhibit high expression levels in GCF samples from individuals with periodontal disease. This suggests modulation of autophagy and the signaling mechanism for pyroptotic cell death in periodontal tissues during pathogenesis. Consequently, the miR-223/RAB12 axis might represent a plausible link for periodontal disease.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lobular capillary hemangioma with an intraosseous feeder vessel through an accessory buccal foramen in the mandible: A unique case report. 下颌骨小叶状毛细血管瘤,其骨内供养血管穿过附属颊孔:一份独特的病例报告。
Journal of Indian Society of Periodontology Pub Date : 2024-01-01 Epub Date: 2024-06-04 DOI: 10.4103/jisp.jisp_197_23
Subash Chandra Raj, Asit Kumar Mishra, Shaheda Tabassum, Debajani Baral
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