{"title":"Desquamative gingivitis: A suspected herpes zoster manifestation?","authors":"Rinda Sharma, Aditi Sangwan, Harneet Singh","doi":"10.4103/jisp.jisp_291_25","DOIUrl":"https://doi.org/10.4103/jisp.jisp_291_25","url":null,"abstract":"<p><p>Desquamative gingivitis (DG) can be caused by multiple etiologic factors, such as herpes zoster (HZ) and allergic reactions to drugs. Infrequently, a patient may be affected by two different pathologic conditions simultaneously, capable of causing oral and cutaneous lesions, thereby resulting in one condition being overlooked. Since DG is a broad term that encompasses numerous conditions, many of which present with similar cutaneous features, periodontists must be aware of this possibility to provide timely and optimal patient care. The present case report seeks to highlight an atypical oral presentation in a case of suspected HZ infection in a young, systemically healthy female with a history of drug allergy.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 2","pages":"324-327"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shalini Mundra, Neetha J Shetty, R Vani Lakshmi, Dhruv Ahuja
{"title":"Comparative evaluation of chorion allograft and sub-epithelial connective tissue autograft for the treatment of isolated mandibular recession with laterally closed tunnel (LCT) technique- A pilot study.","authors":"Shalini Mundra, Neetha J Shetty, R Vani Lakshmi, Dhruv Ahuja","doi":"10.4103/jisp.jisp_166_25","DOIUrl":"https://doi.org/10.4103/jisp.jisp_166_25","url":null,"abstract":"<p><strong>Background: </strong>Mandibular recession remains challenging because of anatomical limitations, including frenulum attachment, tooth position, and vestibular depth. The laterally closed tunnel (LCT) technique offers a minimally invasive approach for root coverage. This pilot study compared the effectiveness of LCT with chorion membrane (CM) allograft and subepithelial connective tissue graft (CTG) in isolated mandibular Miller's Class I, II, and III recessions.</p><p><strong>Materials and methods: </strong>Six healthy patients with isolated mandibular recession defects ≥3 mm were treated with LCT combined with either CM (test group) or CTG (control group). Three patients received CTG and three received CM. The primary outcome was complete root coverage (CRC) at 12 months.</p><p><strong>Results: </strong>No significant postoperative complications were observed. At 12 months, CRC was achieved in 4 of 6 defects (75%), including 3 in the control group and 1 in the test group. The remaining defects exhibited 75% and 66% root coverage. Mean recession depth decreased from 4.00 mm to 0.00 mm in the control group and from 3.67 mm to 0.67 mm in the test group. Keratinized gingival width increased similarly in both groups. Mean root coverage was 100% in the control group and 75% in the test group (<i>P</i> = 0.193).</p><p><strong>Conclusion: </strong>LCT with CM appears to be a promising alternative to CTG for isolated mandibular recession treatment. Larger randomized controlled trials with longer follow-up are needed to confirm these findings and evaluate potential advantages, including reduced donor-site morbidity.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 2","pages":"297-301"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13630353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Silent surge: Palatal hematoma unveiling the intricacies of local anesthesia complications.","authors":"Sunita Kumari, Sayli Langote, Surabhi Amborkar","doi":"10.4103/jisp.jisp_105_25","DOIUrl":"https://doi.org/10.4103/jisp.jisp_105_25","url":null,"abstract":"<p><p>The hard palate is one of the frequent sites of local complications after administration of local anesthetics. Hard, recalcitrant palatal tissues associated with forceful or excessive administration of solution, induction of trauma, use of contaminated solutions, or reactivation of latent viruses may represent or exacerbate local complications in the palatal region. Ulceration and necrosis are uncommon, rare complications of local anesthesia. The aim of this case report was to inform dentists about a rare complication after local anesthesia and how to manage it. A rare case of palatal necrotic hematoma in a 35-year-old male patient after periodontal flap surgery is reported. The course of treatment was conservative for 15 days. After a month, the condition heals so no additional care is needed.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 2","pages":"338-341"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148766414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deeksha Chaudhary, Pradeep Kumar Yadalam, P R Ganesh
{"title":"Modeling sRNA-mRNA regulatory interactions in <i>Staphylococcus aureus</i> from peri-implantitis using a graph attention autoencoder.","authors":"Deeksha Chaudhary, Pradeep Kumar Yadalam, P R Ganesh","doi":"10.4103/jisp.jisp_566_25","DOIUrl":"https://doi.org/10.4103/jisp.jisp_566_25","url":null,"abstract":"<p><strong>Introduction: </strong>Microbial dysbiosis and chronic infection are linked to peri-implantitis, a complex inflammatory disease. <i>Staphylococcus aureus</i>, capable of stress adaptation, immune evasion, and antibiotic resistance, is increasingly recognized as a major cause of implant infections. These traits are regulated by small RNA (sRNA), but the regulatory environment in oral settings remains poorly understood. This study employs empirical sRNA-messenger RNA (mRNA) interaction data and a graph-based method to analyze these regulatory circuits.</p><p><strong>Materials and methods: </strong>Using a curated cross-linking, ligation, and sequencing of hybrids dataset of sRNA-mRNA interactions in <i>S. aureus</i>, we implemented a hybrid graph attention autoencoder (GAT-AE). Interaction scores were encoded as edge weights to construct a bipartite graph. The model used a feedforward decoder to reconstruct interaction scores and graph attention layers to learn 64-dimensional node embeddings. Mean squared error, mean absolute error, and coefficient of determination (<i>R</i> <sup>2</sup>) were used to assess the model's performance.</p><p><strong>Results: </strong>The model identified SprX and RsaE as key regulatory sRNAs that govern antibiotic resistance, stress responses, and metabolic adaptation. Because of its role in immune evasion, the spa mRNA has become a major regulatory target. The model identified co-regulated clusters, reconstructed the overall network structure, and captured biologically significant patterns, despite modest predictive accuracy (<i>R</i> <sup>2</sup> = 0.01).</p><p><strong>Conclusion: </strong>This study demonstrates the utility of GAT-AE models for investigating posttranscriptional regulation in <i>S. aureus</i>, particularly in the context of peri-implantitis. Identifying sRNA hubs involved in survival and virulence lays the groundwork for future diagnostic and therapeutic approaches targeting sRNA-mediated pathways in oral infections.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 2","pages":"213-220"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of photobiomodulation on diabetic human gingival and periodontal ligament fibroblasts: An <i>in vitro</i> study.","authors":"Purva Vijay Bakshi, Swati B Setty, Mallikarjun Goni, Palaksha Kanive Javaregowda","doi":"10.4103/jisp.jisp_18_25","DOIUrl":"https://doi.org/10.4103/jisp.jisp_18_25","url":null,"abstract":"<p><strong>Aim: </strong>This <i>in vitro</i> study was conducted to evaluate the effects of photobiomodulation (PBM) with 940 nm diode LASER on diabetic human gingival fibroblasts (DHGF) and diabetic human periodontal ligament fibroblasts (DPDLF) obtained from patients with poorly controlled diabetes mellitus.</p><p><strong>Materials and methods: </strong>DHGF and DPDLF were isolated and harvested from patients with poorly controlled Type 2 diabetes mellitus (HbA1c > 8). The cells were seeded separately in cell-culture plates and exposed to 940 nm diode LASER at 0.1 W power and 2 J or 4 J energy. The cells were exposed once, twice or thrice at 24 h intervals. Cell viability, proliferation, and migration were assessed in test and control groups via Trypan Blue Assay, MTS Assay, and Scratch Test Assay. The experiment was performed in the form of triplicate.</p><p><strong>Results: </strong>Overall, the DHGF and DPDLF, which were exposed to PBM, exhibited better viability, proliferation, and migration than their corresponding controls. Cell viability was significantly higher in DHGF exposed thrice to 4 J energy at 24-h intervals (<i>P</i> < 0.05). As per the MTS assay analysis, PBM at 2 J energy accelerated cellular proliferation in DHGF and DPDLF (<i>P</i> < 0.05). The scratch test assay revealed significantly smaller wounds at 12 h and 24 h in all irradiated groups than in controls, suggesting faster cell migration.</p><p><strong>Conclusion: </strong>PBM using 940 nm diode at 0.1 W power and delivering 2 J energy could be a valuable tool for enhancing periodontal healing in patients with poorly controlled diabetes.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 2","pages":"283-289"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148759415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality assessment of YouTube™ videos on gingival recession and its management: A cross-sectional analysis of content reliability and educational value.","authors":"Hadeel Mazin Akram, Rasha Salah Abood","doi":"10.4103/jisp.jisp_284_25","DOIUrl":"https://doi.org/10.4103/jisp.jisp_284_25","url":null,"abstract":"<p><strong>Background: </strong>Gingival recession affects approximately 81% of people worldwide and represents one of the most common oral health issues. Increasingly, more people are using digital platforms to find information about their health, with YouTube represented as a popular source for learning about oral health topics. However, studies have not been conducted on the quality or trustworthiness of gingival recession information that is available on YouTube.</p><p><strong>Objective: </strong>To systematically evaluate the content quality, usefulness, and reliability of YouTube™ videos concerning gingival recession and its management using validated assessment tools.</p><p><strong>Materials and methods: </strong>A cross-sectional analysis was conducted using four search terms: \"gingival recession,\" \"gum recession treatment,\" \"receding gums,\" and \"gum graft.\" Twenty videos that met the inclusion criteria were independently evaluated by two calibrated dental evaluators using the Global Quality Scale (GQS), audiovisual quality assessment, and a customized usefulness index. Videos were classified by source (expert vs. non-expert) and content level (high vs. low). Statistical analysis examined the relationships between quality metrics and video characteristics.</p><p><strong>Results: </strong>Expert-created videos comprised 85% of the sample, significantly higher than previously reported for other dental topics. The mean GQS score was 3.4 ± 0.9, indicating moderate-to-good overall quality. High-content videos accounted for 70% of the sample and expert videos demonstrated significantly superior quality across all metrics (GQS: 3.5 vs. 2.7, <i>P</i> < 0.05; usefulness index: 8.2 vs. 5.3, <i>P</i> < 0.01). Content analysis revealed strong coverage of treatment procedures (80%) but significant gaps in prevention education (35%) and practical considerations (15%).</p><p><strong>Conclusions: </strong>YouTube videos concerning gum recession had better quality in terms of content than did videos pertaining to other dental subjects. Videos found on YouTube were at a high level in terms of professional input and contained a moderate-to-high amount of educational information. There was little or no information provided in YouTube videos related to prevention as well as full patient instruction. Therefore, it appears that while YouTube can be a viable source for providing patients with educational materials, there are some subject matter areas that need greater emphasis by professionals.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 2","pages":"269-276"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148765026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anitha Krishnan Pandarathodiyil, Ramya Ramadoss, K Hema Shree, Saranya Chinnadurai, Pratibha Ramani, B Sivapathasundharam
{"title":"Multivariate analysis of treatment choices, disease activity, comorbidities, and oral impairments in rheumatoid arthritis patients.","authors":"Anitha Krishnan Pandarathodiyil, Ramya Ramadoss, K Hema Shree, Saranya Chinnadurai, Pratibha Ramani, B Sivapathasundharam","doi":"10.4103/jisp.jisp_48_25","DOIUrl":"https://doi.org/10.4103/jisp.jisp_48_25","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease that affects the synovial joints and is often associated with multiple comorbidities. Emerging evidence suggests a bidirectional link between RA and periodontal inflammation, wherein shared inflammatory mediators contribute to disease severity and therapeutic outcomes.</p><p><strong>Objective: </strong>The objective of the study was to examine the relationships among demographic and clinical characteristics, comorbidities, periodontal impairment assessed using Russell's Periodontal Index, systemic disease activity measured by Disease Activity Score (DAS28) and C-reactive protein (CRP), and treatment regimens in patients with RA.</p><p><strong>Materials and methods: </strong>A cross-sectional cohort of 33 patients clinically diagnosed with RA (21 seropositive and 12 seronegative) was analyzed. Demographic, serological, and clinical data were retrieved from medical records and verified during follow-up consultations. Russell's Index was used to quantify periodontal involvement, whereas disease activity was assessed using the DAS28 score, which incorporates CRP levels. Details of comorbidities and prescribed treatments, hydroxychloroquine (HCQ), corticosteroids, or combination therapy, were documented. Descriptive and correlational analyses were performed to evaluate associations between disease activity, oral impairment, and therapeutic approach.</p><p><strong>Results: </strong>The cohort comprised 91% females, with a mean age of 46.5 ± 9.8 years. Seropositive RA was identified in 64% of patients. The mean Russell's Index was 2.42 in the RA<sup>+</sup> and 1.92 in the RA<sup>-</sup> groups, showing greater periodontal impairment in seropositive cases. Hypertension (12%), diabetes (6%), and hypothyroidism (6%) were the most frequent comorbidities. Combination therapy (HCQ + steroids) was most commonly prescribed (36%) and associated with higher DAS28 and Russell's scores. A positive correlation was noted between disease activity and periodontal index values.</p><p><strong>Conclusion: </strong>Both systemic comorbidities and oral inflammatory burden influence RA severity. Integrating periodontal assessment with systemic disease monitoring enables more precise, personalized therapy selection. Russell's Index, in conjunction with DAS28 and CRP, may serve as a useful adjunctive marker for therapeutic stratification in RA.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 2","pages":"221-229"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13472474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148766045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of periodontal ligament stem cell viability and proliferation on native collagen membranes: An <i>in vitro</i> study.","authors":"Vineetha Venugopalan, Karishma Ashok, Biju Thomas, Basavarajappa Mohana Kumar, Sudhir Varma, Amitha Ramesh, Sanpreet Singh Sachdev","doi":"10.4103/jisp.jisp_324_25","DOIUrl":"10.4103/jisp.jisp_324_25","url":null,"abstract":"<p><strong>Background: </strong>Periodontal ligament stem cells (PDLSCs) are mesenchymal stem cells with potential for periodontal regeneration. Native collagen membranes are widely used scaffolds due to their biocompatibility and support for cell growth. This study aimed to evaluate the viability, proliferation, and characterization of PDLSCs cultured on native collagen membranes.</p><p><strong>Materials and methods: </strong>Human PDLSCs were isolated from healthy premolars and cultured using explant techniques. Morphology was assessed using phase-contrast microscopy, while viability and population doubling time were measured using trypan blue exclusion. Clonogenic potential was evaluated using a colony-forming unit assay. Immunophenotyping was performed by flow cytometry for mesenchymal markers (CD73, CD90, and CD105) and negative hematopoietic markers (CD34 and CD45). Multilineage differentiation was tested using osteogenic and adipogenic media. The biocompatibility of collagen membrane eluates and scaffolds was evaluated using water-soluble tetrazolium salt-1 and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assays.</p><p><strong>Results: </strong>Four PDLSC lines exhibited high viability (>99%) and retained fibroblast-like morphology. Flow cytometry confirmed mesenchymal marker expression. Cells showed successful osteogenic and adipogenic differentiation. Both direct seeding and eluate exposure from collagen membranes supported PDLSC viability and proliferation, particularly at 24-h eluate intervals.</p><p><strong>Conclusion: </strong>Native collagen membranes are biocompatible scaffolds that support PDLSC proliferation, offering promise for future periodontal regenerative therapies.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"87-93"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Basim Burhan Kurudamparambil Badarudhin, John Roshan, Gireesan Anitha Adersh
{"title":"Three-year follow-up of a peri-implantitis case managed by titanium brush and tetracycline slurry for surface decontamination with guided bone regeneration.","authors":"Basim Burhan Kurudamparambil Badarudhin, John Roshan, Gireesan Anitha Adersh","doi":"10.4103/jisp.jisp_395_24","DOIUrl":"10.4103/jisp.jisp_395_24","url":null,"abstract":"<p><p>Peri-implantitis is one of the frequent complications associated with dental implants. Although several protocols have been given by different authors, there is no unified protocol for the management of peri-implantitis. A male patient aged 74 years reported to the department of implantology with a chief complaint of pain and swelling around the implants in regions 36 and 37. Probing depths ranging from 4 to 7 mm (Williams probe) were noted in respect to 36 and 37. Initial management was done nonsurgically by antibiotics and oral prophylaxis. Deep pockets and bleeding on probing persisted on re-evaluation. Surgical management involved elevation of a full-thickness mucoperiosteal flap, followed by thorough soft-tissue curettage using plastic curettes. The implant surface was detoxified with a tetracycline-saline slurry in conjunction with a titanium brush. Xenograft particulates were used to restore the osseous defect. Postoperative healing was uneventful, and probing depths were within the normal limits. Bleeding on probing was noted below 10%. Significant bone fill was also evident. This case report reveals successful management of peri-implantitis using regenerative procedures.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"141-144"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peripheral ossifying fibroma associated with an underlying enamel pearl on an anterior tooth.","authors":"Neha Aggarwal, Aditi Sangwan, Shikha Tewari, Anjali Narwal, Ankita Ramani","doi":"10.4103/jisp.jisp_223_24","DOIUrl":"10.4103/jisp.jisp_223_24","url":null,"abstract":"<p><p>Peripheral ossifying fibroma (POF) is a reactive gingival lesion characterized by high cellularity and varying degrees of mineralization. An 18-year-old female reported a painless enlargement in the lower right anterior region that had been gradually increasing in size over five years. Clinically, the lesion appeared as a pink, smooth-surfaced, sessile mass involving the interdental papilla and attached gingiva adjacent to the mandibular right lateral incisor. There was no history of trauma. Following scaling and root planing, an excisional biopsy was performed. Intraoperatively, an enamel pearl measuring 2 mm × 3 mm was identified at the cementoenamel junction of the involved tooth and removed after flap elevation. Histopathological examination confirmed the diagnosis of POF. The postoperative healing was uneventful, with no recurrence observed over a one-year follow-up period. This case highlights the unusual association of POF with an underlying enamel pearl.</p>","PeriodicalId":15890,"journal":{"name":"Journal of Indian Society of Periodontology","volume":"30 1","pages":"150-153"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}