{"title":"Influence of Sodium Hypochlorite Heating Method, Activation Technique, and Concentration on Organic Tissue Removal in Simulated Internal Resorption Cavities.","authors":"Emek Bayındır, Öznur Sarıyılmaz, Rüya Sessiz","doi":"10.1016/j.joen.2026.02.019","DOIUrl":"10.1016/j.joen.2026.02.019","url":null,"abstract":"<p><strong>Introduction: </strong>This in vitro study aimed to evaluate the effects of sodium hypochlorite (NaOCl) heating method, activation technique, and concentration on organic tissue removal from simulated internal resorption cavities.</p><p><strong>Methods: </strong>A total of 198 single-rooted resin teeth with simulated internal resorption cavities were included. To simulate organic tissue, the cavities were filled with bovine muscle tissue. Specimens were allocated into 18 groups (n = 11) according to heating method (room temperature, intracanal heating, or extracanal heating), NaOCl concentration (5.25% or 2%), and activation technique (standard needle irrigation, passive ultrasonic irrigation, or XP-endo Finisher). Baseline cone-beam computed tomography scans were obtained before irrigation. Following irrigation and activation procedures, residual organic tissue was assessed using cone-beam computed tomography and the percentage of residual organic tissue was calculated. Statistical analysis was performed with the significance level set at P < .05.</p><p><strong>Results: </strong>XP-endo Finisher resulted in significantly less residual organic tissue than standard needle irrigation under all temperature and concentration conditions. Passive ultrasonic irrigation showed superior tissue removal compared with standard needle irrigation only when 5.25% NaOCl was used with intracanal heating; no significant differences were observed under the other temperature and concentration conditions. Within the XP-endo Finisher groups, heating methods did not significantly influence tissue removal efficacy. In the passive ultrasonic and standard needle irrigation groups, extracanal heating generally yielded greater tissue removal than room temperature. Across all temperature conditions in the passive ultrasonic groups, and in the extracanal heating subgroup of standard needle irrigation, 5.25% NaOCl showed significantly greater tissue dissolution than 2% NaOCl.</p><p><strong>Conclusions: </strong>XP-endo Finisher demonstrated superior organic tissue removal regardless of irrigation temperature or NaOCl concentration. When standard needle irrigation or passive ultrasonic irrigation was used, extracanal heating of NaOCl enhanced its tissue-dissolving capacity, whereas increasing NaOCl concentration improved dissolution efficiency primarily in passive ultrasonic irrigation.</p>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endodonticsPub Date : 2026-03-01Epub Date: 2025-11-14DOI: 10.1016/j.joen.2025.11.005
Sıla Nur Usta DDS , Emmanuel João Nogueira Leal Silva DDS, MSc, PhD , Hilal Tekkanat DDS , Cangül Keskin DDS, PhD
{"title":"Virtual Reality Haptic Simulators and Mobile Applications—Potential AI-enhanced Tools for Improving Clinical Endodontic Training: A Randomized Controlled Trial","authors":"Sıla Nur Usta DDS , Emmanuel João Nogueira Leal Silva DDS, MSc, PhD , Hilal Tekkanat DDS , Cangül Keskin DDS, PhD","doi":"10.1016/j.joen.2025.11.005","DOIUrl":"10.1016/j.joen.2025.11.005","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to evaluate the effects of a virtual reality haptic simulator (VRHS, VirTeaSy Dental) and a mobile application (Dental EndoMaster) on the manual competency, stress, and self-confidence levels of 4th-year dental students in endodontic clinical practice.</div></div><div><h3>Methods</h3><div>Thirty dental students were randomly assigned to 3 groups as follows (<em>n</em> = 10): Group 1 (VRHS), Group 2 (mobile application), and Group 3 (control). Before clinical training, Groups 1 and 2 completed 3 standardized practice sessions and one final assessment session using VRHS and a mobile application. In contrast, Group 3 directly started with the clinical procedure without prior exposure to VRHS or the mobile application. All students performed access cavity preparations on maxillary incisors diagnosed with chronic apical periodontitis. Clinical performance was evaluated by an endodontist. Self-clinical scores and drilling time were recorded. Upon the termination of clinical practice, students completed a self-confidence survey. Stress levels were measured using a visual analog scale at different time points. Statistical analyses were conducted with significance set at <em>P</em> < .05.</div></div><div><h3>Results</h3><div>Students in Group 1 showed significantly higher clinical and self-clinical scores and reduced drilling time compared to Group 3 (<em>P</em> < .05). Students in Groups 1 and 2 exhibited lower stress levels before the clinical procedures (<em>P</em> < .05). Groups 1 and 2 reported greater self-confidence and perceived preparedness for clinical endodontic procedures compared to Group 3.</div></div><div><h3>Conclusions</h3><div>The integration of artificial inteligence-enhanced VRHS and a mobile application into endodontic training significantly enhanced students’ clinical performance, reduced stress levels, and increased self-confidence during their first clinical procedures.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 3","pages":"Pages 337-344"},"PeriodicalIF":3.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145533827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endodonticsPub Date : 2026-03-01Epub Date: 2025-11-06DOI: 10.1016/j.joen.2025.10.017
Chang Liu DDS , Longfei Ma PhD , Yaopeng Zhang MEng , Yanmei Dong PhD , Xudong Bao PhD
{"title":"Research on Registration Strategy for Guided Endodontics","authors":"Chang Liu DDS , Longfei Ma PhD , Yaopeng Zhang MEng , Yanmei Dong PhD , Xudong Bao PhD","doi":"10.1016/j.joen.2025.10.017","DOIUrl":"10.1016/j.joen.2025.10.017","url":null,"abstract":"<div><h3>Introduction</h3><div>The objective of this study was to evaluate which registration strategy (the number, configuration, and distribution range of fiducial markers) could obtain the optimal registration accuracy for guided root canal therapy.</div></div><div><h3>Methods</h3><div>One 3-dimensional-printed mandibular jaw model was created. The fiducial markers used for registration were prepared on the crowns of anterior and posterior teeth. The models were scanned using cone-beam computed tomography, and digital models were built. Different numbers (3, 4, 6, 8, and 10), configurations (quadrilateral, triangular, and linear) and distribution ranges (target tooth, adjacent teeth, and mandibular dentition) of fiducial markers were applied for registration of the dynamic navigation system. The target registration error (TRE) was measured. One-way analysis of variance was applied to assess registration error between groups. The significance level was set at .05.</div></div><div><h3>Results</h3><div>The TREs of 4 markers were significantly lower than those of three for both anterior tooth (0.32 mm vs 0.62 mm; <em>P</em> < .05) and posterior tooth (0.22 mm vs 1.43 mm; <em>P</em> < .05); increasing the number of markers to ten did not further reduce the TREs (<em>P</em> > .05). The TREs of markers arranged in a quadrilateral configuration were significantly lower than those in linear and triangular configurations (<em>P</em> < .05). The TREs of the markers selected on the target tooth and adjacent teeth were significantly lower than those in the mandibular dentition region for anterior tooth (<em>P</em> < .05).</div></div><div><h3>Conclusions</h3><div>In endodontic treatment, the best registration accuracy was obtained by selecting four spatial quadrilateral fiducial markers localized around the target tooth.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 3","pages":"Pages 429-435"},"PeriodicalIF":3.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145476925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endodonticsPub Date : 2026-03-01Epub Date: 2025-11-21DOI: 10.1016/j.joen.2025.10.008
Hajar Albanyan BDS, MSc, Dip ABE , Mohammed Asseery DMD , Haitham Alahmari DDS , Ikram Ul Haq MLIS , Ali Alaqla BDS, CAGS, MS, FRCDC, Dip ABE, DMSc
{"title":"Top 100 Most Cited Articles on Antibiotics in Endodontics: A Bibliometric Analysis","authors":"Hajar Albanyan BDS, MSc, Dip ABE , Mohammed Asseery DMD , Haitham Alahmari DDS , Ikram Ul Haq MLIS , Ali Alaqla BDS, CAGS, MS, FRCDC, Dip ABE, DMSc","doi":"10.1016/j.joen.2025.10.008","DOIUrl":"10.1016/j.joen.2025.10.008","url":null,"abstract":"<div><h3>Introduction</h3><div>This bibliometric study aimed to evaluate the 100 most cited articles on antibiotics in endodontics using the Web of Science database.</div></div><div><h3>Methods</h3><div>Articles were identified using the keywords “Endodontics” AND “Antibiotics” and ranked by citation count. Key bibliometric indicators including publication and citation trends, study designs, levels of evidence, top sources, authors, countries, institutions, and most frequently occurring keywords were analyzed using Microsoft Excel version-16 and Visualization of Similarities Viewer.</div></div><div><h3>Result</h3><div>The top 100 most cited articles were published between 1954 and 2022, across 40 different sources, and were authored by 397 researchers from 30 countries. Most publications (76%) were from 2006 to 2019. The United States, Brazil, and England were the leading contributors. Cross-sectional studies and reviews were the most common designs with level of evidence V dominating the database and showing the highest citation impact. The Journal of Endodontics and International Endodontic Journal were the top sources.</div></div><div><h3>Conclusion</h3><div>This upward trend over the past 2 decades reflects advancements in oral health education and growing research interest. This analysis highlights the influential publications and research trends, offering valuable insights for future studies, clinical practice, and academic collaboration in antibiotic used for endodontic therapy.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 3","pages":"Pages 345-352"},"PeriodicalIF":3.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145587689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endodonticsPub Date : 2026-03-01Epub Date: 2026-01-07DOI: 10.1016/j.joen.2025.12.003
Hinpetch Daungsupawong PhD, Viroj Wiwanitkit MD
{"title":"Letter to the Editor: Comparing the Effectiveness of a Robotic and Dynamic Navigation System in Fiber Postremoval: An In Vitro Study","authors":"Hinpetch Daungsupawong PhD, Viroj Wiwanitkit MD","doi":"10.1016/j.joen.2025.12.003","DOIUrl":"10.1016/j.joen.2025.12.003","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 3","pages":"Page 334"},"PeriodicalIF":3.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145911888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endodonticsPub Date : 2026-03-01Epub Date: 2026-01-27DOI: 10.1016/j.joen.2025.12.004
Duo Zhou MDS, Fulu Xu MDS, Jiayun Dai MDS, Xingyang Wang MDS, Yifan Ping MDS, Juan Wang PhD, DDS
{"title":"Authors’ Reply to the Commentary on “Comparing the Effectiveness of a Robotic and Dynamic Navigation System in Fiber Post Removal: An In Vitro Study”","authors":"Duo Zhou MDS, Fulu Xu MDS, Jiayun Dai MDS, Xingyang Wang MDS, Yifan Ping MDS, Juan Wang PhD, DDS","doi":"10.1016/j.joen.2025.12.004","DOIUrl":"10.1016/j.joen.2025.12.004","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 3","pages":"Pages 335-336"},"PeriodicalIF":3.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146064208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endodonticsPub Date : 2026-03-01Epub Date: 2026-03-06DOI: 10.1016/S0099-2399(26)00046-4
{"title":"Guidelines for Authors","authors":"","doi":"10.1016/S0099-2399(26)00046-4","DOIUrl":"10.1016/S0099-2399(26)00046-4","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 3","pages":"Pages A9-A10, A12, A14-A18"},"PeriodicalIF":3.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147428097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of endodonticsPub Date : 2026-03-01Epub Date: 2025-12-09DOI: 10.1016/j.joen.2025.11.024
Mariana Pereira de Souza da Silva MSc , Adriana da Costa Ribeiro PhD , Jeynifer Rafaella Bezerra de Oliveira PhD , Daniel Amancio Duarte MSc , Bruno Felipe de Carvalho BSc , Yaicel Ge Proenza PhD , Natália Maria Velozo dos Santos Mendonça MSc , Anderson Stevens Leonidas Gomes PhD
{"title":"Apical Dentin Microcrack Formation After Ultrasonic Instrumentation in Flattened Root Canals: A Comparative Analysis Using Micro-computed Tomography and Optical Coherence Tomography","authors":"Mariana Pereira de Souza da Silva MSc , Adriana da Costa Ribeiro PhD , Jeynifer Rafaella Bezerra de Oliveira PhD , Daniel Amancio Duarte MSc , Bruno Felipe de Carvalho BSc , Yaicel Ge Proenza PhD , Natália Maria Velozo dos Santos Mendonça MSc , Anderson Stevens Leonidas Gomes PhD","doi":"10.1016/j.joen.2025.11.024","DOIUrl":"10.1016/j.joen.2025.11.024","url":null,"abstract":"<div><h3>Introduction</h3><div>Although ultrasonic inserts are frequently used for the instrumentation of flat root canals, there is a lack of studies investigating whether instrument contact with the canal walls induces the formation of dentinal microcracks. This study aimed to evaluate the formation of apical microcracks, caused by ultrasonic instrumentation, using micro-computed tomography (microCT) and optical coherence tomography (OCT).</div></div><div><h3>Method</h3><div>Twenty maxillary second premolars were randomly divided into 2 groups (<em>n</em> = 10): ultrasonic group and brushing group. All specimens were initially prepared using Reciproc Blue files 25/.05 and 40/.06. The brushing group received additional brushing movements with Reciproc Blue 40/.06 and the ultrasonic group underwent instrumentation with a Clearsonic Black ultrasonic insert. Pre- and post-instrumentation images were obtained using both microCT and OCT and were analyzed with specialized software.</div></div><div><h3>Results</h3><div>Statistically significant difference was observed for the treatment variable regarding apical microcrack presence (<em>P</em> < .05). In the brushing group, all apical microcracks identified post-instrumentation were also present preoperatively. In contrast, new incidences were identified in the ultrasonic group via microCT. No significant differences were found for the evaluator (<em>P</em> > .05) or the imaging technique used (<em>P</em> > .05). Intra- and interexaminer agreement was nearly perfect, with kappa values ranging from 0.858 to 0.975.</div></div><div><h3>Conclusion</h3><div>The inclusion of an ultrasonic insert during biomechanical preparation did not significantly increase the incidence of apical microcracks when compared with a nonultrasonic protocol. OCT demonstrated high reliability for detecting apical microcracks in extracted teeth.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 3","pages":"Pages 458-463"},"PeriodicalIF":3.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145742942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}