Journal of endodontics最新文献

{"title":"Associate Registry","authors":"","doi":"10.1016/S0099-2399(26)00301-8","DOIUrl":"10.1016/S0099-2399(26)00301-8","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1221-1231"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148429270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Healing Patterns of Odontogenic Maxillary Sinusitis Following Nonsurgical Endodontic Therapy: A Cone-Beam Computed Tomography-Based Case Series","authors":"Guofeng Yang MD, PhD","doi":"10.1016/j.joen.2026.03.013","DOIUrl":"10.1016/j.joen.2026.03.013","url":null,"abstract":"<div><div>This case series evaluated the differential healing patterns of maxillary sinus mucosa and periapical bone following nonsurgical root canal treatment for odontogenic maxillary sinusitis to propose a prognostic perspective based on distinct radiographic features. Ten cases of odontogenic maxillary sinusitis managed by primary nonsurgical root canal treatment or retreatment were categorized into 4 radiographic patterns based on periapical and sinus lesions. Clinical symptoms were recorded, and radiographic healing was assessed using cone-beam computed tomography (CBCT) at baseline and during follow-up periods ranging from approximately 3–17 months. All cases showed clinical symptoms recovery and sinus opacities radiographic resolution. Maxillary sinus mucosal lesions, including extensive opacification and sinus floor perforations, resolved to a normal physiological thickness (&lt;2 mm) within approximately 3 months. Conversely, periapical alveolar bone regeneration required a longer progress (approximately 3–17 months) to demonstrate radiographic healing. Cases with extensive bone destruction or periosteal displacement (periapical osteoperiostitis/halo sign) showed delayed bone healing. Within the limits of this case series, maxillary sinus mucosa appears to heal faster than periapical tissues, typically resolving within 3 months. Although periapical radiographs remain useful for evaluating sinus floor perforation and extensive bone destruction, CBCT offers superior three-dimensional assessment in anatomically complex cases or when radiographs are inconclusive. We suggest that, in selected cases, early postoperative CBCT evidence of mucosal resolution (approximately 3 months) may be considered as an adjunctive early indicator of treatment response, while acknowledging that periapical bone regeneration often lags and requires longer follow up.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1206-1213.e6"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147574239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric Mapping of Mandibular Incisor Root Canals and Its Implications for Instrument Size-taper Selection","authors":"Carolina Oliveira de Lima DDS, MSc, PhD ,&nbsp;Emmanuel João Nogueira Leal Silva DDS, MSc, PhD ,&nbsp;Laís Vieira Maciel DDS ,&nbsp;Júlia de Brito Montan DDS ,&nbsp;Ana Flávia Almeida Barbosa DDS, MSc, PhD ,&nbsp;Marco Aurélio Versiani DDS, MSc, PhD","doi":"10.1016/j.joen.2026.03.009","DOIUrl":"10.1016/j.joen.2026.03.009","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to characterize the morphology of mandibular incisor root canals and to evaluate their correspondence with commonly used nickel–titanium (NiTi) instruments.</div></div><div><h3>Methods</h3><div>One hundred extracted human mandibular incisors were scanned using high-resolution micro-computed tomography. Minor and major canal diameters and aspect ratios were measured at 1-mm intervals from the apical foramen to 10 mm coronally. Canal cross-sections were classified as round, long-oval, or flat based on aspect ratio. A supplementary analysis determined the percentage frequency of canals with diameters equal to or smaller than a wide range of size-taper combinations of constant-taper NiTi instruments. An 80% frequency threshold was applied to identify meaningful correspondence between canal dimensions and instrument sizes. Descriptive statistics were calculated, and the association between major and minor diameters was assessed using Pearson's correlation coefficient.</div></div><div><h3>Results</h3><div>Both minor and major canal diameters increased progressively in the coronal direction, although enlargement of the major diameter was more pronounced from the middle third coronally. Round canals predominated in the apical region, whereas long-oval canals were most prevalent in the middle and coronal thirds; flat canals occurred mainly between 6 and 7 mm from the apex. Correspondence between NiTi instruments and the minor canal diameter depended strongly on instrument taper, with larger tapers required for smaller tip sizes to reach the 80% threshold. In contrast, correspondence with the major canal diameter was markedly limited across all instrument sizes and tapers, with no instrument achieving ≥80% correspondence along the entire root length. The correlation between minor and major canal diameters was weak, indicating disproportionate enlargement of canal dimensions.</div></div><div><h3>Conclusions</h3><div>Mandibular incisors present pronounced anatomical asymmetry, particularly in the middle and coronal thirds, resulting in limited correspondence between conventional NiTi instruments and the major canal diameter.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1186-1193"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147520981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regenerative Endodontic Procedures: Mapping and Critical Appraisal of Clinical Trial Evidence","authors":"Felipe Oliveira Nunes MD,&nbsp;Eduardo Borges Sollim MD,&nbsp;Carolynne Ferreira dos Santos MD,&nbsp;Maria Karolina Martins Ferreira PhD,&nbsp;João Daniel Mendonça Moura PhD,&nbsp;Juliana Melo Brandão PhD,&nbsp;Manoel Damião Sousa-Neto PhD,&nbsp;Paulo Jorge Palma PhD,&nbsp;Rafael Rodrigues Lima PhD","doi":"10.1016/j.joen.2026.02.017","DOIUrl":"10.1016/j.joen.2026.02.017","url":null,"abstract":"<div><h3>Introduction</h3><div>Regenerative endodontic procedures (REPs) are biologically based approaches aimed at restoring the vitality of immature teeth with pulp necrosis. Over the past decades, these procedures have gained increasing attention. This study mapped and critically appraised the clinical trial evidence on REPs, providing an overview of research trends and methodological characteristics.</div></div><div><h3>Methodology</h3><div>A comprehensive bibliometric analysis was conducted following Bibliometric Reviews of the Biomedical Literature guidelines using the Web of Science Core Collection database. Randomized and nonrandomized clinical trials available in the database up to 2025 were included, covering the full period of indexed clinical evidence on REPs. Quantitative variables (citations, countries, journals, and keywords) and qualitative aspects (techniques, materials, irrigants, intracanal medications, and barriers) were analyzed.</div></div><div><h3>Results</h3><div>Among the 6,287 retrieved records, 58 clinical studies met the inclusion criteria. The most productive authors were De-Jesus-Soares A, Gomes BPFA, Kang J, Nazzal H, and Elheeny AAH. The most cited author was Xuan K, with 346 citations. Asia was the most productive continent, and the Journal of Endodontics published the highest number of studies. The most frequent keywords were regenerative endodontics, revascularization, and immature teeth. Blood clot induction was the predominant regenerative technique, while sodium hypochlorite, triple antibiotic paste, and mineral trioxide aggregate were the most commonly used irrigant, intracanal medication, and barrier material, respectively.</div></div><div><h3>Conclusions</h3><div>Clinical evidence on REPs suggests a consolidation of biologically based strategies, particularly blood clot induction with mineral trioxide aggregate barriers. However, methodological heterogeneity limits the strength and comparability of findings, highlighting the need for standardized protocols and long-term randomized studies.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1082-1104"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147326241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Outcomes of Predoctoral Root Canal Therapy: Retreatment and Tooth Loss in a 17-year Institutional Cohort","authors":"Farzad Baghaie BS ,&nbsp;Nahid Kashani DDS, MSD, FAGD ,&nbsp;Farhad Kevin Baghaie DDS","doi":"10.1016/j.joen.2026.04.009","DOIUrl":"10.1016/j.joen.2026.04.009","url":null,"abstract":"<div><h3>Introduction</h3><div>Nonsurgical root canal therapy (RCT) is predictable; however, some teeth develop post-treatment disease requiring retreatment or extraction. This study evaluated the durability of predoctoral RCT by quantifying retreatment and tooth loss within a single institutional cohort.</div></div><div><h3>Methods</h3><div>This retrospective chart review used Axium records from January 1, 2008, through October 31, 2025. All nonsurgical RCTs in the predoctoral clinic (<em>n</em> = 7,340) were identified. Phase I quantified retreatment frequency. Phase II characterized retreated teeth by diagnosis, radiographic quality, intracoronal core placement, restoration status, and timing. Phase III linked RCTs to extraction codes to assess tooth loss and time-to-event patterns. Descriptive statistics, Kaplan–Meier analyses, and an exploratory two-by-two analysis of retreatments attributed to suspected coronal leakage and restoration status were performed.</div></div><div><h3>Results</h3><div>Of 7,340 RCTs, 131 teeth underwent retreatment (1.78%) and 531 were extracted (7.23%), yielding a 9.02% combined adverse outcome rate. Retreatment occurred at a median of 1.21 years and was most commonly attributed to suspected coronal leakage, obturation deficiencies, and missed canals. Teeth without documented intracoronal core placement demonstrated earlier retreatment and higher odds of retreatment attributed to suspected coronal leakage without definitive restoration (odds ratio 1.98; 95% confidence interval 0.99–3.97). Extractions occurred at a median of 2.10 years, with no survival differences among tooth types.</div></div><div><h3>Conclusion</h3><div>Retreatment after predoctoral RCT was uncommon, whereas extraction occurred more frequently. Early retreatments and later extractions represent distinct endpoints, emphasizing durable coronal sealing and timely definitive restoration for long-term tooth retention.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1157-1165"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147773071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Analysis of Clinical Characteristics and Therapeutic Effect of Intentional Replantation","authors":"Jiani Zhu MDS,&nbsp;Xiangfen Li DDS, PhD,&nbsp;Qin Su DDS, PhD","doi":"10.1016/j.joen.2026.02.006","DOIUrl":"10.1016/j.joen.2026.02.006","url":null,"abstract":"<div><h3>Introduction</h3><div>A retrospective analysis of a large group of cases was conducted to examine the clinical traits of teeth subjected to intentional replantation (IR) and the factors influencing the treatment effect, so as to provide guidance for indication selection and surgical operations.</div></div><div><h3>Methods</h3><div>A total of 445 patients, each with one affected tooth, underwent IR surgery at West China Hospital of Stomatology, Sichuan University, from 2016 to 2023, were included. Data on basic patient information, preoperative status, intraoperative procedures, and follow-up results for 107 patients with a follow-up duration exceeding 1 year were collected. Statistical analysis was performed using SPSS.</div></div><div><h3>Results</h3><div>The results showed that most IR patients were female (62.25%) and aged between 21 and 50 (80.45%). The predominant teeth for surgery were the mandibular second molars (44. 94%), maxillary second molars (19.33%), and maxillary lateral incisors (11.24%). The main preoperative symptoms were percussion pain (78. 65%), periodontal pockets (50.11%), sinus tract (40.45%), and tooth mobility (30.79%). The rate of completing preoperative root canal treatment was 93.71%. During surgery, 66 teeth (14.83%) had root surface cracks. Sixty-two of these teeth were not reimplanted during the operation; 47 of 62 (75.81%) had vertical root fractures. The overall success rates were 78.50%. Univariate analysis showed that the lack of periodontal pockets and the absence of bony plate defects significantly increased the success rate (P &lt; .05). The success rate for severe coronal defects and root defects on the distal surface of the second molar was 73.68%.</div></div><div><h3>Conclusion</h3><div>IR can be used for complex endodontic and periapical diseases, as well as teeth with periodontitis, serving as a viable solution for salvaging challenging teeth. The periodontal status, initial etiology, and the severity of the bony plate defect are key prognostic factors.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1114-1125"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into the July 2026 Issue of the JOE","authors":"Anita Aminoshariae DDS, MS,&nbsp;Amir Azarpazhooh DDS, MSc, PhD, FRCD(C),&nbsp;Gerald N. Glickman DDS, MS, MBA, JD,&nbsp;Jianing He DMD, PhD,&nbsp;Sahng G. Kim DDS, MS,&nbsp;Anil Kishen BDS, MDS, PhD,&nbsp;Ariadne M. Letra DDS, MS, PhD,&nbsp;Linda Levin DDS, PhD,&nbsp;Ronald Ordinola-Zapata,&nbsp;Frank C. Setzer DMD, PhD, MS,&nbsp;Franklin R. Tay BDSc(Hons), PhD,&nbsp;Kenneth M. Hargreaves DDS, PhD","doi":"10.1016/j.joen.2026.05.011","DOIUrl":"10.1016/j.joen.2026.05.011","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1079-1081"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation of Postoperative Pain and Clinical Success Following Rotary and Reciprocating Instrumentation in Teeth with Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial","authors":"İrem Deniz DDS ,&nbsp;Mehmet Emin Kaval DDS, PhD ,&nbsp;Michael Hülsmann DDS, PhD ,&nbsp;Gözde Kandemir Demirci DDS, PhD","doi":"10.1016/j.joen.2026.04.006","DOIUrl":"10.1016/j.joen.2026.04.006","url":null,"abstract":"<div><h3>Introduction</h3><div>The aim of this study was to evaluate the clinical success rate and the effects of different root canal shaping systems (hand files, reciprocating, and rotary) on postoperative pain in patients with symptomatic irreversible pulpitis (SIP) in vital mandibular molars.</div></div><div><h3>Methods</h3><div>A total of 63 patients with a Numerical Rating Scale pain score ≥7 and SIP in mandibular first or second molars were included. Patients were randomly divided into 3 groups (<em>n</em> = 21) and root canal shaping was performed using reciprocating or rotary files; preparation using hand files served as the control. Irrigation was performed using sodium hypochlorite and EDTA, calcium hydroxide was used for temporary medication. In all cases, obturation was completed using AH Plus Bioceramic sealer in a second appointment one week later. Postoperative pain was assessed using the Numerical Rating Scale at 6, 12, and 24 hours after the emergency appointment, and on days 2 through 7 and day 30, postoperatively. Clinical success was evaluated clinically and radiographically after 6 and 12 months.</div></div><div><h3>Results</h3><div>Although the postoperative pain decreased over time in all groups (<em>P</em> &lt; .05), it did not differ significantly between the groups (<em>P</em> &gt; .05). Despite the lack of significance, the hand file group reported higher pain levels at most follow-up intervals. Clinical success was 96.8% at 6 months and 85.7% at 12 months, respectively, with a significant correlation observed between the level of root canal filling and treatment success at 12 months (<em>P</em> &lt; .05). No significant difference between the instrument systems in terms of success was observed.</div></div><div><h3>Conclusions</h3><div>In symptomatic and severely painful vital teeth, the hand files, reciprocating and rotary systems showed comparable levels of postoperative pain.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1126-1135"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147716928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"External Cervical Resorption Treatment: Case Report and Outcome-based Strategies","authors":"Terrell F. Pannkuk DDS, MScD","doi":"10.1016/j.joen.2026.04.004","DOIUrl":"10.1016/j.joen.2026.04.004","url":null,"abstract":"<div><div>External cervical resorption (ECR) is a complex dental condition that is traditionally treated with external surgical repair and nonsurgical root canal therapy as needed. This case report describes a patient with 8 teeth treated for ECR. Follow-up examination and management strategies are described, using microscopic techniques, three-dimensional imaging, and bioactive root filling materials. The chosen techniques were based on the severity of ECR, root location, defect geometry, and management of the portals of entry. Access to the external resorption defect was achieved through the root canal system, while considering the potential need for later external surgical repair. Materials were chosen for root filling and defect repair based on viscosity, bioactivity, physical strength, and handling properties. The treatment protocol included multiple visits to ensure definitive lesion debridement, root sealing, and material setting. The case highlights stable healing in different types of ECR defects. From a restorative perspective, posts were considered undesirable, because they could interfere with bioactive material placement, particularly in cases where later revision is required. This case supports a systematic treatment approach for saving teeth with ECR that were previously considered candidates for extraction.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages 1214-1220"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147673953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guidelines for Authors","authors":"","doi":"10.1016/S0099-2399(26)00283-9","DOIUrl":"10.1016/S0099-2399(26)00283-9","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"52 7","pages":"Pages A13-A20"},"PeriodicalIF":3.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148565536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}