Journal of endodontics最新文献

{"title":"Associate Registry","authors":"","doi":"10.1016/S0099-2399(24)00269-3","DOIUrl":"https://doi.org/10.1016/S0099-2399(24)00269-3","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141067127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Dr Tuttle","authors":"Tyler Dolphin DDS, MS, Sara Fowler DMD, MS, Melissa Drum DDS, MS, John Nusstein DDS, MS, Al Reader DDS, MS","doi":"10.1016/j.joen.2024.05.001","DOIUrl":"10.1016/j.joen.2024.05.001","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photoinactivation of Enterococcus faecalis Biofilm: In Vitro Antimicrobial Effect of Photoexcited Rutin-Gallium(III) Complex via Visible Blue Light","authors":"Maryam Pourhajibagher PhD ,&nbsp;Hassan-Ali Ghafari DDS, MSc ,&nbsp;Rashin Bahrami DDS, MSc ,&nbsp;Abbas Bahador PhD","doi":"10.1016/j.joen.2024.01.007","DOIUrl":"10.1016/j.joen.2024.01.007","url":null,"abstract":"<div><h3>Introduction</h3><p>Endodontic infection is a common problem that can result in tooth loss if not effectively treated. This study focused on investigating the use of rutin-gallium (Ga)(III) complex–mediated antimicrobial photodynamic therapy (aPDT) for the photoinactivation of <em>Enterococcus faecalis</em> biofilm.</p></div><div><h3>Methods</h3><p>The minimum biofilm eradication concentration of the rutin-Ga(III) complex and the minimum biofilm eradication dose of light-emitting diode against <em>E. faecalis</em> were evaluated. The antimicrobial effect of rutin-Ga(III) complex–mediated aPDT against <em>E. faecalis</em> was assessed. Additionally, the expression of genes associated with <em>E. faecalis</em> virulence, such as <em>ace</em>, <em>gelE</em>, and <em>esp</em>, as well as the production of reactive oxygen species within the cells were evaluated.</p></div><div><h3>Results</h3><p>The minimum biofilm eradication concentration of the rutin-Ga(III) complex was determined to be 25 μmol/L, whereas the minimum biofilm eradication dose of light-emitting diode irradiation was defined as 5 minutes with an energy density of 300–420 J/cm². Rutin-Ga(III) complex–mediated aPDT demonstrated a significant dose-dependent reduction in the growth of <em>E. faecalis</em> biofilms. Moreover, aPDT led to increased intracellular reactive oxygen species generation in treated <em>E. faecalis</em> cells. Furthermore, the messenger RNA levels of <em>ace</em>, <em>gelE</em>, and <em>esp</em> genes were significantly down-regulated in <em>E. faecalis</em> treated with rutin-Ga(III) complex–mediated aPDT (<em>P</em> &lt; .05).</p></div><div><h3>Conclusions</h3><p>Rutin-Ga(III) complex–mediated aPDT effectively reduces <em>E. faecalis</em> biofilm growth by disrupting biofilm structure and down-regulating virulence genes. These findings highlight the potential of aPDT with the rutin-Ga(III) complex as an adjuvant therapeutic approach against <em>E. faecalis</em> biofilms.</p></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139516232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dear Dr. Bogen","authors":"","doi":"10.1016/j.joen.2024.02.015","DOIUrl":"10.1016/j.joen.2024.02.015","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140012698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into the May 2024 Issue of the Journal of Endodontics","authors":"Anita Aminoshariae DDS, MS,&nbsp;Amir Azarpazhooh DDS, MSc, PhD, FRCD(C),&nbsp;Ashraf F. Fouad DDS, MS,&nbsp;Gerald N. Glickman DDS, MS, MBA, JD,&nbsp;Jianing He DMD, PhD,&nbsp;Sahng G. Kim DDS, MS,&nbsp;Anil Kishen BDS, MDS, PhD,&nbsp;Ariadne M. Letra DDS, MS, PhD,&nbsp;Linda Levin DDS, PhD,&nbsp;Frank C. Setzer DMD, PhD, MS,&nbsp;Franklin R. Tay BDSc(Hons), PhD,&nbsp;Kenneth M. Hargreaves DDS, PhD","doi":"10.1016/j.joen.2024.04.001","DOIUrl":"10.1016/j.joen.2024.04.001","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140626163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Donor Honor Roll","authors":"","doi":"10.1016/S0099-2399(24)00238-3","DOIUrl":"https://doi.org/10.1016/S0099-2399(24)00238-3","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140818230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pericervical Dentin Metrics in Mandibular First Molars Determined with Digital Periapical Radiography and Cone-beam Computed Tomography","authors":"Carlos Boveda Od, Endod, Esp Endod, PhD ,&nbsp;Anil Kishen BDS, MDS, PhD ,&nbsp;Beatriz Millan Od, Esp Endod, PhD ,&nbsp;María V. Camejo Od, Esp Endod, PhD ,&nbsp;Jose Francisco Gomez-Sosa DDS, PhD","doi":"10.1016/j.joen.2024.02.003","DOIUrl":"10.1016/j.joen.2024.02.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Pericervical root dentin is decisive for the long-term mechanical integrity of root-filled teeth. Current treatment protocol does not include a customized step to determine the pretreatment residual pericervical root dentin.</p></div><div><h3>Objective</h3><p>To determine and compare the residual root dentin and canal width using digital periapical radiography (DPR) and cone-beam computed tomography (CBCT) at the apical limit of the pericervical area (PCA) in mandibular first molars.</p></div><div><h3>Methods</h3><p>DPR and CBCT images of 60 patients with age between 22 and 76 years were used to determine (a) the mesiodistal widths of the root canal (pericervical dimensions [PCL]-C) and the root (PCL-R) of mandibular first molars at the apical limit of the PCA and (b) the intracanal distance from the apical limit of the PCA to the radiographic apex (intracanal distance [ICD]). The correlation between the PCL and ICD measurements obtained from DPR and CBCT were evaluated.</p></div><div><h3>Results</h3><p>Values between 0.10–0.80 mm and 0.00–1.10 mm were obtained for PCL-C using DPR and CBCT respectively (95% CI). The PCL values between 0.90–2.30 mm and 0.00–2.30 mm were obtained from DPR and CBCT respectively (95% CI). The ICD ranged between 4.6–12.3 mm in DPR and 4.40–12.0 mm in CBCT (95% CI). The comparative analysis showed differences from −0.9 to 0.5 mms for PCL and −2.00 to 1.5 mms for ICD between DPR and CBCT techniques respectively.</p></div><div><h3>Conclusion</h3><p>The PCL and ICD determined from DPR and CBCT provided the pericervical dentin metrics that could be utilized clinically as a guideline for decision-making in endodontic treatment.</p></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139741193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Irrigation Techniques for Cleaning Efficiency in Isthmus Structures","authors":"David Donnermeyer PD Dr.med.dent. ,&nbsp;Patricia Claire Dust Cand.med.dent. ,&nbsp;Edgar Schäfer Prof.Dr.med.dent. ,&nbsp;Sebastian Bürklein Prof.Dr.med.dent.","doi":"10.1016/j.joen.2024.02.008","DOIUrl":"10.1016/j.joen.2024.02.008","url":null,"abstract":"<div><h3>Introduction</h3><p>This study aimed to evaluate the removal of a biofilm-mimicking hydrogel from isthmus structures in a simulated complex root canal system consisting of 2 curved root canals by Laser-activated irrigation (LAI, AdvErl Evo, Morita) and mechanical activation techniques.</p></div><div><h3>Methods</h3><p>A 3D-printed root canal model with 2 parallel root canals (60°-curvature, radius 5 mm, dimension 25/.06) with a total length of 20 mm connected via isthmuses (2.5 × 0.4 × 0.2 mm) at 5 mm and 8 mm from the apical endpoint and with lateral canals (diameter 0.2 mm) in all directions at 2, 5, and 8 mm from the apex was filled with a colored biofilm-mimicking hydrogel. Irrigation protocols under continuous irrigation with distilled water (3 × 20s per root canal; 3 ml/20s; <em>n</em> = 20) included conventional needle irrigation (=NI); manual agitation (=MA, gutta-percha point 25/.06); EndoActivator (=SAI-EA, 25/.04); EDDY (=SAI-E, 25/.04); ultrasonically-activated irrigation (=UAI) and LAI (Er:YAG-laser; P400FL tip at canal entrance; 25pps, 50 mJ, 300μs). Removal of the hydrogel was determined as a percentage via standardized photos through a microscope. Statistical analysis was performed using Kruskal–Wallis and Conover tests (<em>P</em> = .05).</p></div><div><h3>Results</h3><p>Laser-activated irrigation (LAI) was associated with the greatest removal of hydrogel from the entire root canal system (<em>P</em> &lt; .05), followed by SAI-E. No significant differences were reported for the coronal isthmus between LAI, SAI-E, NI, and MA (<em>P</em> &gt; .05), but inferior results for SAI-EA and UAI (<em>P</em> &lt; .05). In the apical isthmus, all techniques outperformed UAI (<em>P</em> &lt; .05), with LAI, SAI-E, and NI showing the best results (<em>P</em> &lt; .05).</p></div><div><h3>Conclusions</h3><p>Laser-activated irrigation (LAI) was superior to other irrigation techniques in the entire root canal system. SAI-E and NI performed comparable to LAI in the isthmuses.</p></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0099239924001006/pdfft?md5=8ed5d6cbb1769e5d85eda660809ad66e&pid=1-s2.0-S0099239924001006-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139924193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associate Registry","authors":"","doi":"10.1016/S0099-2399(24)00218-8","DOIUrl":"https://doi.org/10.1016/S0099-2399(24)00218-8","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140818229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evaluation of Anti-Osteoclastic Activity of the Novel Calcium Hydroxide Biodegradable Nanoparticles as an Intracanal Medicament","authors":"Patarawadee Promta DDS ,&nbsp;Patcharaporn Chaiyosang DDS ,&nbsp;Aussara Panya PhD ,&nbsp;Pongrapee Laorodphun MS ,&nbsp;Warat Leelapornpisid DDS, PhD ,&nbsp;Napatsorn Imerb DDS, PhD","doi":"10.1016/j.joen.2024.02.023","DOIUrl":"10.1016/j.joen.2024.02.023","url":null,"abstract":"<div><h3>Introduction</h3><p>The aim of this study was to evaluate the anti-osteoclastic activity of calcium hydroxide–loaded poly(lactic-co-glycolic acid) nanoparticles [Ca(OH)₂-loaded PLGA NPs] in comparison to calcium hydroxide nanoparticles [Ca(OH)₂ NPs].</p></div><div><h3>Methods</h3><p>RAW 264.7 cell lines (third–fifth passage) were cultured and incubated with soluble receptor activator of nuclear factor kappa B ligand in triplicate. Subsequently, Ca(OH)₂-loaded PLGA NPs and Ca(OH)₂ NPs were added for 7 days to evaluate their effects on receptor activator of nuclear factor kappa B ligand–induced osteoclast differentiation of RAW 264.7 cells by tartrate-resistant acid phosphatase activity. Additionally, a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was conducted to confirm the cytotoxicity of treatments to cells.</p></div><div><h3>Results</h3><p>Tartrate-resistant acid phosphatase staining showed a significant reduction in the osteoclast number when treated with Ca(OH)₂-loaded PLGA NPs compared with Ca(OH)₂ NPs (<em>P</em> &lt; .01). In comparison to the control, the number of osteoclasts significantly reduced upon treatment with Ca(OH)₂-loaded PLGA NPs (<em>P</em> &lt; .05), but there was no significant difference in Ca(OH)₂ NPs. Furthermore, osteoclast morphology in both treatment groups exhibited smaller sizes than the control group. Neither Ca(OH)₂-loaded PLGA NPs nor Ca(OH)₂ NPs demonstrated cytotoxic effects on RAW264.7 cells.</p></div><div><h3>Conclusions</h3><p>Both Ca(OH)₂ NPs with and without poly(lactic-co-glycolic acid) have the ability to inhibit osteoclast differentiation. However, Ca(OH)₂-loaded PLGA NPs exhibit greater potential than Ca(OH)₂ NPs, making them a promising intracanal medicament for cases of root resorption.</p></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140049634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}