Anita Aminoshariae DDS, MS, Amir Azarpazhooh DDS, MSc, PhD, FRCD(C), Gerald N. Glickman DDS, MS, MBA, JD, Jianing He DMD, PhD, Sahng G. Kim DDS, MS, Anil Kishen BDS, MDS, PhD, Ariadne M. Letra DDS, MS, PhD, Linda Levin DDS, PhD, Ronald Ordinola-Zapata, Frank C. Setzer DMD, PhD, MS, Franklin R. Tay BDSc(Hons), PhD, Kenneth M. Hargreaves DDS, PhD
{"title":"Insights into the October 2025 Issue of the JOE","authors":"Anita Aminoshariae DDS, MS, Amir Azarpazhooh DDS, MSc, PhD, FRCD(C), Gerald N. Glickman DDS, MS, MBA, JD, Jianing He DMD, PhD, Sahng G. Kim DDS, MS, Anil Kishen BDS, MDS, PhD, Ariadne M. Letra DDS, MS, PhD, Linda Levin DDS, PhD, Ronald Ordinola-Zapata, Frank C. Setzer DMD, PhD, MS, Franklin R. Tay BDSc(Hons), PhD, Kenneth M. Hargreaves DDS, PhD","doi":"10.1016/j.joen.2025.09.005","DOIUrl":"10.1016/j.joen.2025.09.005","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1339-1341"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Congyu Yang BDSc, Yi Min BDSc, MSc, PhD, Wei Fan BDSc, MSc, PhD
{"title":"Cyclic Fatigue Evaluation of Nickel-Titanium Rotary Instruments Using an Electrical Resistance-based Method","authors":"Congyu Yang BDSc, Yi Min BDSc, MSc, PhD, Wei Fan BDSc, MSc, PhD","doi":"10.1016/j.joen.2025.06.015","DOIUrl":"10.1016/j.joen.2025.06.015","url":null,"abstract":"<div><h3>Introduction</h3><div>This <em>in vitro</em><span> study aimed to establish the correlation between electrical resistance and cyclic fatigue of endodontic nickel-titanium (NiTi) rotary instruments as a quantifiable cyclic fatigue indicator.</span></div></div><div><h3>Methods</h3><div>Two kinds of geometrically identical NiTi rotary instruments ProTaper Universal F2 and ProTaper Gold F2 were selected and allocated into 2 experimental groups: a cyclic fatigue test<span> group and a sterilization test group. In the cyclic fatigue test group, instruments were rotated in an artificial root canal until fracture, with the number of cycles (rotations) to fracture (NCF) recorded. In the sterilization test group, instruments were rotated to 20%, 40%, 60%, and 80% of the NCF, followed by autoclaving sterilization. Electrical resistance was measured after each 10 rotations, as well as pre- and post-sterilization. Scanning electron microscopy was applied to analyze the instrument surfaces, focusing on the expanding of microcracks over rotations and the effect of autoclaving. The collected data were then statistically analyzed.</span></div></div><div><h3>Results</h3><div>The results indicated that the electrical resistance of tested instruments increased quadratically with the cyclic fatigue degrees along with the expanding of microcracks. At the 80% NCF, the electrical resistance increased by 2.38% and 2.63% for PTU F2 and PTG F2 respectively. Autoclaving had no significant effect on electrical resistance.</div></div><div><h3>Conclusion</h3><div>Electrical resistance could be used as a quantifiable indicator to evaluate and predict the cyclic fatigue degree of NiTi rotary instruments and seems unaffected by autoclaving.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1471-1476"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deniz Erdogan PhD , Ali Erdemir PhD , Ercan Tekin MD
{"title":"The Effect of Different Chelating Agents in Different Application Times on the Release of Growth Factors from Dentin","authors":"Deniz Erdogan PhD , Ali Erdemir PhD , Ercan Tekin MD","doi":"10.1016/j.joen.2025.05.006","DOIUrl":"10.1016/j.joen.2025.05.006","url":null,"abstract":"<div><h3>Introduction</h3><div><span>The purpose of this study was to evaluate the effect of ethylene diamine tetra acetic acid (EDTA), </span>etidronic acid<span> (HEBP), boric acid (BA), or saline at different application times on transforming growth factor-β1 (TGF-β1), vascular endothelial growth factor-A, and insulin-like factor-1 (IGF-1) release levels from inner root dentin.</span></div></div><div><h3>Methods</h3><div>Seventy-five root segments, obtained from extracted fully developed premolar<span><span> human teeth, were standardized to 8 mm long and prepared with Gates Glidden burs number 1-4 for simulating an open apex. The samples were irrigated with 1.5% sodium hypochlorite and then divided into 4 main groups according to chelation agents (17% EDTA, 9% HEBP, 6% BA, or saline) and 3 subgroups according to application times. TGF-β1, vascular endothelial growth factor-A, and IGF-1 release levels were measured on the 1st and 7th days by enzyme-linked immunosorbent assay. The final concentrations were calculated based on the root canal volume measured by cone-beam </span>computed tomography<span>. Data were compared using a one-way analysis of variance, the Tukey test, Kruskal Wallis, and Wilcoxon test.</span></span></div></div><div><h3>Results</h3><div>In all growth factors (GFs), the EDTA group had a statistically significantly higher release than the saline group (<em>P</em> < .001). Increasing EDTA application time did not affect statistically significant GFs release (<em>P</em> >.05). All GFs were released more on the 7th than the 1st day.</div></div><div><h3>Conclusions</h3><div>The release levels of GFs vary according to the type of chelating agent and application time. BA in the release of IGF-1 and HEBP in the release of TGF-β1 were as effective as EDTA at all application times.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1446-1454"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reinforcing Effect of Intraradicular Filling Materials in Simulated Immature Mandibular Premolars with Mineral Trioxide Aggregate Apical Barrier: A Weibull Analysis","authors":"Ploy Opacharoensuk DDS , Danuchit Banomyong DDS, PhD , Kanet Chotvorrarak DDS, MSc , Pimchanok Suphanarongpun DDS , Sittichoke Osiri DDS, MSc","doi":"10.1016/j.joen.2025.04.003","DOIUrl":"10.1016/j.joen.2025.04.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Incomplete root formation following pulp necrosis requires mineral trioxide aggregate (MTA) apexification. Although effective, this treatment does not increase the root thickness, necessitating additional reinforcement. This study aimed to evaluate the fracture resistance of simulated immature mandibular premolars apexified with MTA and reinforced with various materials using Weibull analysis.</div></div><div><h3>Methods</h3><div>Ninety human mandibular first premolars were prepared to simulate immature teeth. After MTA apexification, teeth were divided into six groups: negative control (intact teeth), positive control (untreated apexified teeth), gutta-percha (GP) with AH Plus, GP with Bioceramic sealer, core, and fiber post/core. The teeth underwent thermocycling, periodontal ligament simulation, and fracture testing.</div></div><div><h3>Results</h3><div>Negative and positive controls exhibited the highest and lowest fracture resistance, respectively. Core and fiber post/core had hazard ratios of 4.79 and 6.23, respectively, outperforming GP with AH Plus and GP with Bioceramic sealer (hazard ratios: 14.23 and 17.22, respectively). Most fractures occurred in the coronal third.</div></div><div><h3>Conclusions</h3><div>Intraradicular reinforcement materials (fiber post/core and core) provided greater support to MTA-apexified roots than conventional root filling materials (GP/AH Plus and GP/Bioceramic sealer).</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1438-1445"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Single versus Multiple-stage Restorative Approaches on the Pulp Outcomes of Symptomatic Vital Cracked Teeth: A Systematic Review and Meta-analysis","authors":"Dimitrios Gavriil DDS, MClinDent , Angeliki Kakka DDS, MSc , Massimo Del Fabbro MSc, PhD","doi":"10.1016/j.joen.2025.06.013","DOIUrl":"10.1016/j.joen.2025.06.013","url":null,"abstract":"<div><h3>Introduction</h3><div>This systematic review aimed to compare single-stage treatment (SST) and multiple-stage treatment (MST) regarding pulp survival, pulp success, and tooth survival in symptomatic vital cracked teeth and to assess the influence of secondary interventions and baseline factors on pulp outcomes.</div></div><div><h3>Methods</h3><div>Electronic searches were conducted in PubMed, Scopus, Web of Science, Cochrane Library, and “Gray Literature” through December 3, 2024, supplemented by hand searching. Clinical studies reporting pulp survival of permanent symptomatic vital cracked teeth with ≥1-year follow-up after complete SST or MST were included. Risk of bias was evaluated using the Newcastle-Ottawa Scale and the Revised Cochrane risk-of-bias tool. A single-arm random-effects meta-analysis was performed. The certainty of the body of evidence was assessed via the Grading of Recommendations Assessment, Development and Evaluation approach.</div></div><div><h3>Results</h3><div><span>Fourteen cohort studies qualified. No significant difference was observed between SST and MST for 1- or 2-year pulp survival and 1-year pulp success (</span><em>P</em> > .05). However, SST with indirect restorations demonstrated significantly higher pulp success than MST with indirect (<em>P</em> < .05) and SST with direct (<em>P</em> < .001). Indirect onlays exhibited superior pulp outcomes compared to crowns (<em>P</em> < .05). Direct restorations were comparable to onlays for pulp survival (<em>P</em> > .05) but inferior for pulp success (<em>P</em> < .001). Short duration of interim treatment (1–2 weeks) yielded greater pulp success than long duration (2–3 months) (<em>P</em> < .05). One-year tooth survival was consistently high (96.1%–100%). The certainty of evidence was graded as very low due to the inclusion of observational studies and substantial between-study heterogeneity.</div></div><div><h3>Conclusions</h3><div>This review suggests with very low level of certainty that SST with indirect restorations may improve pulp success over MST. Onlays outperform crowns, while direct restorations may not fully alleviate symptoms. Short interim treatment duration is preferable in MST. Timely intervention is critical for tooth survival.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1362-1375"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah J. Ermoshkin DDS, MS , Al M. Best PhD , Patricia A. Tordik DMD
{"title":"Gender Equity in Endodontic Scholarship and Academia","authors":"Sarah J. Ermoshkin DDS, MS , Al M. Best PhD , Patricia A. Tordik DMD","doi":"10.1016/j.joen.2025.06.021","DOIUrl":"10.1016/j.joen.2025.06.021","url":null,"abstract":"<div><h3>Introduction</h3><div>Our hypothesis explored representation in women's leadership positions in endodontic academia to assess publication participation of men and women from 2010 to 2023 and to test academic rank disparities by comparing men and women faculty rank, gender, and citation impact.</div></div><div><h3>Methods</h3><div>Authors' names were downloaded from a PubMed search of publications in the <em>Journal of Endodontics, International Endodontic Journal,</em> and <em>Dental Traumatology</em> between 2010 and 2023. Editorial board members and reviewers were obtained from journal pages. Gender API software was used to determine gender based on first names. Fifty-four United States endodontic postgraduate departments were identified on the American Association of Endodontists website in 2022, and faculty information and rank were verified on departmental websites. Respective H-index scores were calculated using Harzing's Publish or Perish software.</div></div><div><h3>Results</h3><div>Of the 36,587 authors, 35% were women, and the percentage of women authors increased by 0.5% per year (95% CI = 0.3–0.6). Compared to women, men published more than women, outnumbered women as reviewers, and held more positions on editorial boards. The educational leadership of the United States endodontics programs is 29% women. Women comprise 23% of chairs, 21% of postgraduate directors, and 47% of predoctoral director positions (<em>P</em> = .013). However, among academic leaders in the United States, faculty rank is not associated with gender (<em>P</em> = .396) after scholarly impact and leadership roles are adjusted for.</div></div><div><h3>Conclusions</h3><div>Ultimately, the leadership role predicts rank, not gender. This suggests that women need to take action to apply for more leadership positions.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1376-1383"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Frequency and Performance Analysis of Polymer, Steel, and Titanium Ultrasonic Inserts in Intracanal Medication Removal","authors":"Guilherme Nilson Alves dos Santos DDS, MSc, PhD , Alice Corrêa Silva-Sousa DDS, PhD , Angelo José Sócrates Torres-Carrillo DDS, MSc , Guilherme de Araujo Braz PhD , Thais Oliveira Alves DDS, MSc , Fabiane Carneiro Lopes-Olhê DDS, MSc, PhD , Yara Teresinha Corrêa Silva-Sousa DDS, MSc, PhD , Jardel Francisco Mazzi-Chaves DDS, MSc, PhD , Ricardo Gariba Silva DDS, MSc, PhD , Manoel Damião Sousa-Neto DDS, MSc, PhD","doi":"10.1016/j.joen.2025.06.003","DOIUrl":"10.1016/j.joen.2025.06.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Ultrasonic inserts can be manufactured in various shapes, angles, and materials, this study evaluated the frequencies generated by steel, titanium, and polymer ultrasonic inserts using acoustic wave analysis and assessed the effectiveness of the iVac system and passive ultrasonic irrigation (PUI) compared to conventional irrigation for removing calcium hydroxide-based intracanal medication using micro-computed tomography (microCT).</div></div><div><h3>Methods</h3><div>Steel and titanium inserts from the Ultra X system (blue, silver, gold) and the polymer insert from the iVac system were analyzed using vibroacoustography in Ultra X (45 kHz) and Woodpecker (40 kHz) ultrasonic devices. Inserts were positioned in a water tank for standardized placement. The excitation signal was generated using MATLAB software, and power measurements were conducted in duplicate. After root canal preparation in 30 teeth, calcium hydroxide-based medication was applied and scanned using microCT. After 7 days, initial removal was performed with a K-file (number 45.02), followed by three protocols: conventional irrigation, PUI, or iVac. A second microCT scan was performed. Analysis of variance and Tukey's tests compared ultrasonic power and residual medication volume.</div></div><div><h3>Results</h3><div>The steel, titanium, and polymer inserts exhibited frequencies from 37 to 45 kHz. The iVac group (99.8 ± 0.3%) achieved greater medication removal than the PUI group (97.3 ± 2.9%), both significantly superior to conventional irrigation (73.0 ± 9.4%) (<em>P</em> < .05).</div></div><div><h3>Conclusion</h3><div>The ultrasonic power of the inserts operated within the expected frequency range. The iVac system demonstrated superior effectiveness in removing intracanal medication.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1455-1463"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feasibility and Clinical Efficacy of Minimally Invasive Straight-Incision Endodontic Microsurgery Guided by 3-Dimensional Printed Templates: A Retrospective Case Series","authors":"Lanxi Guan DDS , Xiao Liu DDS , Chen Cai DDS , Cailing Fang BD , Yidi Lao BD , Jiaxin Huang BD , Yuting Huang DDS , Xuechao Yang PhD, DDS , Qianzhou Jiang PhD, DDS","doi":"10.1016/j.joen.2025.06.006","DOIUrl":"10.1016/j.joen.2025.06.006","url":null,"abstract":"<div><h3>Introduction</h3><div><span>Endodontic<span><span> microsurgery (EMS) is a </span>minimally invasive treatment<span> for persistent periapical lesions. This study evaluates the accuracy and outcomes of a straight-incision EMS guided by 3-dimensional (3D)-printed </span></span></span>template, with at least 1 year of follow-up.</div></div><div><h3>Methods</h3><div>Twelve teeth from nine patients underwent minimally invasive straight-incision EMS using 3D-printed templates and a trephine for both osteotomy<span> and root-end resection. Clinical outcomes, deviations in resection length and angle, and mucosal incision healing were retrospectively assessed.</span></div></div><div><h3>Results</h3><div>Trephine-based root-end resection was successful in all cases, with no intraoperative or postoperative complications. Clinical and radiographic evaluations confirmed success in all patients after 1 year. Median resection length deviation was 0.79 mm (95% confidence interval: 0.49–1.16), and angular deviation was 19° (95% confidence interval: 8.03–25.47). All cases showed favorable and rapid wound healing, except for case 12.</div></div><div><h3>Conclusions</h3><div>Straight-incision EMS guided by 3D-printed templates is a precise, minimally invasive, and esthetically favorable technique that enables accurate root-end resection and promotes effective healing.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1490-1496.e5"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"hDPSC-derived Secretomes Enhance Odontogenic Differentiation and Suppress Inflammation: A Potential Cell-free Approach for Regenerative Endodontics","authors":"Ji-Soo Kim DDS, MSD , Manfei Qiu DDS, MSD, PhD , Kkot-Byeol Bae DDS, MSD, PhD , Ji-Hyun Jang DDS, MSD, PhD , Won-Jae Kim DDS, MSD, PhD , Jeong-Tae Koh DDS, MSD, PhD , Yun-Chan Hwang DDS, MSD, PhD , Bin-Na Lee DDS, MSD, PhD","doi":"10.1016/j.joen.2025.06.016","DOIUrl":"10.1016/j.joen.2025.06.016","url":null,"abstract":"<div><h3>Introduction</h3><div><span>Secretomes are bioactive molecules secreted by stem cells that contain growth factors, anti-inflammatory agents, and proteins involved in tissue repair. This study aimed to evaluate the anti-inflammatory and odontogenic effects of human </span>dental pulp stem cells (hDPSCs)-derived secretomes.</div></div><div><h3>Methods</h3><div><span><span><span>Secretomes were isolated from hDPSCs through stepwise filtration and centrifugation. </span>Gene ontology<span> analysis was performed to characterize the secretome composition. The effects of secretomes on cell migration were assessed via wound healing assay. Anti-inflammatory and odontogenic effects were evaluated using quantitative real-time polymerase chain reaction and </span></span>western blotting<span><span> for inflammatory markers and odontogenic differentiation markers. Alkaline phosphatase staining was performed to assess </span>mineralization under lipopolysaccharide-induced inflammatory conditions. Data were statistically analyzed using one-way analysis of variance and Tukey's posthoc test (</span></span><em>P</em> < .05 was considered significant).</div></div><div><h3>Results</h3><div>Gene ontology analysis confirmed key functional components of the secretome. The wound healing assay demonstrated that 100 μg/mL secretome treatment significantly enhanced human dental pulp cells migration. Secretome treatment significantly attenuated lipopolysaccharide-induced upregulation of inflammatory markers (<em>P</em><span> < .05) while upregulating odontoblastic differentiation markers and promoting mineralization (</span><em>P</em> < .05).</div></div><div><h3>Conclusion</h3><div>hDPSC-derived secretomes exhibit anti-inflammatory and odontogenic effects, potentially mediated by MAPK signaling<span> pathways. These findings suggest that secretomes may serve as a novel cell-free strategy for regenerative endodontics, offering therapeutic potential for vital pulp therapy and dentin-pulp regeneration.</span></div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1420-1428"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Evaluation of Root Canal Retreatment Techniques and the Effect of Supplementary Cleaning on Curved Canals Obturated with Premixed Bioceramic Sealer","authors":"Tanakrit Sutharoj DDS , Anat Dewi DDS, MSc (Endodontics) , Panupat Phumpatrakom DDS, MSc (Endodontics) , Thanapat Sastraruji PhD","doi":"10.1016/j.joen.2025.06.012","DOIUrl":"10.1016/j.joen.2025.06.012","url":null,"abstract":"<div><h3>Introduction</h3><div>The retreatment<span> of curved root canals remains challenging, particularly with the increased use of premixed bioceramic sealers, which exhibit more difficult retrievability. This study aimed to compare the effectiveness of 2 retreatment systems—RECIPROC blue and VDW.ROTATE retreatment—in removing obturation materials from curved canals filled with either a bioceramic sealer (iRoot SP) or an epoxy resin-based sealer (AH Plus). The study also evaluated the additional cleaning effect of XP-endo Finisher R.</span></div></div><div><h3>Methods</h3><div><span>Sixty extracted mandibular molars<span> with mesiobuccal canals possessing 20–40° curvature were divided into 4 groups based on the sealer and retreatment technique used. Canals were obturated with either AH Plus or iRoot SP, followed by retreatment using either RECIPROC blue or VDW.ROTATE retreatment. Supplementary cleaning with XP-endo Finisher R was used in all groups. </span></span>Microcomputed tomography<span> was used to evaluate the volume of residual filling material and apical transportation.</span></div></div><div><h3>Results</h3><div>RECIPROC blue achieved significantly higher success in regaining apical patency compared to VDW.ROTATE retreatment. Supplementary cleaning with XP-endo Finisher R significantly reduced residual materials in all groups.</div></div><div><h3>Conclusion</h3><div>RECIPROC blue is more effective in retreating curved canals filled with bioceramic sealer, and supplementary cleaning using XP-endo Finisher R further enhances canal cleanliness.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1464-1470"},"PeriodicalIF":3.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}