Journal of endodontics最新文献

{"title":"Development of Antimicrobial Peptide-loaded Hydrogels as Potential Scaffolds for Pulp-dentine Complex Regeneration: A Comparative Study","authors":"Parisa Noohi PhD ,&nbsp;Mohammad J. Abdekhodaie PhD ,&nbsp;Mohammad H. Nekoofar DDS, PhD ,&nbsp;Miguel Gama PhD ,&nbsp;Maryam Saadatmand PhD ,&nbsp;Paul M.H. Dummer BDS, MSD, PhD, DDS","doi":"10.1016/j.joen.2025.01.018","DOIUrl":"10.1016/j.joen.2025.01.018","url":null,"abstract":"<div><h3>Introduction</h3><div>As a recently developed treatment modality, regeneration of the pulp-dentin-like complex via tissue engineering approaches is the focus of considerable attention. The persistence of bacteria within the root canal spaces is well known as the major challenge of dental pulp regeneration. Antimicrobial peptides (AMPs) are short peptides with inhibitory activities against a broad spectrum of microorganisms.</div></div><div><h3>Methods</h3><div>In the present study, antimicrobial hydrogels based on 2 photo-reactive biopolymers, that is collagen methacrylate and chitosan methacrylate, and containing 2 different AMPs, that is LLKKK18 and Tet213, were used to develop a potential scaffold with antimicrobial and regenerative features.</div></div><div><h3>Results</h3><div>The incorporation of AMPs had no significant effect on the physical, mechanical, rheological, and morphological properties of the new systems. The optimized concentration of LLKKK18 and Tet213 had appropriate antimicrobial activity against Gram-positive <em>Enterococcus fæcalis</em> and did not exhibit any cytotoxicity to stem cells from the apical papilla encapsulated within the hydrogels compared to the control group without AMPs. The presence of AMPs also significantly promoted migration and differentiation of stem cells from the apical papilla. In the AMP-loaded groups, greater levels of calcified nodules deposition, alkaline phosphatase, collagen type I, dentin sialophosphoprotein, dentin matrix protein 1, and vascular endothelial growth factor A mRNA gene expression, and collagen type I and dentin sialophosphoprotein protein expression were observed.</div></div><div><h3>Conclusions</h3><div>The results indicated the potential of engineered antimicrobial collagen methacrylate/chitosan methacrylate hydrogels for application in tissue engineering-based strategies to regenerate the pulp-dentin complex.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 585-593"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Persistent Post-Endodontic Pain With a Standardized Gabapentin Pyramid Protocol: A Case Series and Clinical Guidelines","authors":"Zakery James DMD ,&nbsp;Biraj Patel BDS, MS ,&nbsp;Jianing He DDS, PhD ,&nbsp;Kenneth M. Hargreaves DDS, PhD ,&nbsp;Nikita B. Ruparel MS, DDS, PhD","doi":"10.1016/j.joen.2025.01.007","DOIUrl":"10.1016/j.joen.2025.01.007","url":null,"abstract":"<div><h3>Introduction</h3><div>Persistent postendodontic pain following endodontic therapy is a rare but substantial clinical challenge. Mechanisms that mediate peripheral neuropathy and/or central sensitization likely play a pivotal role in its development and chronification. The objective of this case series is to describe a management plan for persistent postendodontic pain and provide prescription guidelines using a standardized “Gabapentin Pyramid Protocol” for clinical practice.</div></div><div><h3>Methods</h3><div>Four cases of persistent postendodontic pain are presented. A peripheral etiology for pain was eliminated in all 4 cases. All patients were also refractory to conventional analgesics. Patients received the “Gabapentin Pyramid Protocol.”</div></div><div><h3>Results</h3><div>Three of the 4 cases experienced complete resolution of symptoms within the prescribed treatment period. In 1 case, symptoms were greatly reduced but recurred upon discontinuation of the drug.</div></div><div><h3>Conclusions</h3><div>The “Gabapentin Pyramid Protocol” represents an effective treatment option for persistent postendodontic pain, demonstrating significant symptom relief and potential for complete resolution.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 627-637"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guided Intentional Replantation of a Mandibular Premolar with Type IIIb Dens Invaginatus Associated with Peri-invagination Periodontitis without Root Canal Treatment: A Case Report","authors":"Francesc Abella Sans DDS, PhD ,&nbsp;Marc Garcia-Font DDS, PhD ,&nbsp;Nandini Suresh BDS, MDS, FDS RCS (Eng) ,&nbsp;Paul M.H. Dummer BDS, MScD, PhD, DDSc ,&nbsp;Venkateshbabu Nagendrababu BDS, MDS, FDS RCPS (Glasg), PhD","doi":"10.1016/j.joen.2024.12.017","DOIUrl":"10.1016/j.joen.2024.12.017","url":null,"abstract":"<div><div>This report highlights successful management of a rare case of a mandibular premolar with Oehler's Type IIIb Dens Invaginatus (DI) and peri-invagination periodontitis with guided intentional replantation without root canal treatment. A 22-year-old female patient reported with discomfort and a sinus tract associated with tooth number 21. Clinical examination and cone beam computed tomography revealed tooth number 21 had an Oehler's Type IIIb DI with peri-invagination periodontitis. The patient had partially healed sockets in the number 19 and number 30 regions. Thus, guided intentional replantation for tooth number 21 and guided double autotransplantation in the position of teeth number 19 and number 30 in a single visit was planned. Three-dimensional replicas of the donor teeth (numbers 16 and 32) as well as number 21 with type IIIb DI were printed based on intraoral scanning and cone beam computed tomography images. Tooth number 21 was extracted with its buccal cortical plate and root-end resection followed by root-end filling with mineral trioxide aggregate was performed. The tooth was replanted into the modified socket, and stabilized using a flexible wire-composite splint for 4 weeks. Unfortunately, the patient was lost to follow-up, but reported 2 years later when all teeth were retained without signs of disease. Two years following intentional replantation without root canal treatment, tooth number 21 with an Oehler's Type IIIb DI with peri-invagination periodontitis had no symptoms and radiographic examination revealed a reduction in the dimensions of the peri-invagination periodontitis.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 638-645"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Intra-canal Medicaments on Infrared Light Energy Transmission Through Enamel and Dentin During Photobiomodulation: An In Vitro Study","authors":"Sachin Kulkarni BOHDSc (Hons) Grad Dip Dent ,&nbsp;Laurence J. Walsh BDSc (Hons) (Qld), DDSc (Qld), PhD (Qld), GCEd, FFOP (RCPA), FICD, FADI, FPFA, FIADFE ,&nbsp;Yash Bhurani BDS ,&nbsp;Roy George BDS, MDS, PhD (QLD), MRACDS (Endo), GCHE (QLD), FDS RCS (Edin)","doi":"10.1016/j.joen.2025.01.014","DOIUrl":"10.1016/j.joen.2025.01.014","url":null,"abstract":"<div><h3>Introduction</h3><div>This <em>in vitro</em> study assessed how shade changes induced by endodontic medicaments affect the transmission of single and multiples wavelengths of infrared light through enamel and dentin.</div></div><div><h3>Methods</h3><div>Eighteen extracted single-rooted permanent teeth were prepared, removing all extrinsic staining, and cementum. Tooth slices were treated for 4 weeks with UltraCal XS, Ledermix, or were untreated controls. Light transmission through enamel-dentin and dentin regions was assessed using diode lasers (660, 808, 904 nm) and a multi-wavelength light-emitting diode (LED) light source (700–1100 nm). Absorption studies were performed to evaluate light absorption by components of medicaments.</div></div><div><h3>Results</h3><div>Samples treated with Ledermix showed the greatest shade change, with a corresponding reduction in visible and near infrared light transmission (<em>P</em> &lt; .001) in dentin, whereas UltraCal XS had a milder effect (<em>P</em> &lt; .01). Across different substrates, the greatest light transmission was seen for the multi-wavelength LED light source, followed by 904 nm, 808 nm, and finally 660 nm. Spectrophotometric studies revealed light absorption by turbid and saturated calcium hydroxide solutions.</div></div><div><h3>Conclusions</h3><div>This study shows that medicaments may influence transmission of visible red and near infrared light. Photobiomodulation protocols used in regenerative endodontics should take this effect into account, by incorporating longer near infrared wavelengths (up to 1100 nm) and using multi-wavelength light sources to account for this absorption.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 616-621"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Apical Periodontitis and Autoimmune Diseases: A Systematic Review with Meta-analysis","authors":"Tatiana A.M. do Nascimento MSc ,&nbsp;Francielle S. Verner PhD ,&nbsp;Cleidiel Aparecido Araújo Lemos PhD ,&nbsp;Rafael B. Junqueira PhD","doi":"10.1016/j.joen.2025.01.021","DOIUrl":"10.1016/j.joen.2025.01.021","url":null,"abstract":"<div><h3>Objectives</h3><div>The aim of this study was to perform a qualitative and quantitative synthesis of the available studies evaluating the possible relationship between apical periodontitis and autoimmune diseases.</div></div><div><h3>Methods</h3><div>The literature search was conducted across 6 electronic databases (PubMed/MEDLINE, Embase, SciELO, Web of Science, Cochrane Library, and Scopus). The search covered articles published up to September 2023. There was no disagreement between the 2 reviewers. The RevMan software (V5.3) (Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014) was used for the meta-analysis. A dichotomized analysis was performed using the Mantel–Haenszel statistical method with a fixed-effect model and the risk ratio as the effect measure. A 95% confidence interval was adopted, and the significance level was set at <em>P</em> &lt; .05. The presence of apical periodontitis was predefined as the event, with the experimental group consisting of patients with autoimmune disease and the control group consisting of patients without autoimmune disease (healthy individuals). The data used included the number of individuals presenting the event vs the total number of study participants.</div></div><div><h3>Results</h3><div>Nine studies were included and considered eligible. The methodological quality of the studies was classified as moderate in 5 of the 9 included studies, while 2 were rated as low, and 2 were rated as high-quality. The relative risk was 1.24 with a 95% confidence interval (1.08–1.62), in which the prevalence of apical periodontitis in comparing patients with autoimmune diseases and healthy patients yielded statistically significant results (<em>P</em> &lt; .0001). Thus, patients with autoimmune diseases had a 24% higher relative risk of developing apical periodontitis compared to the healthy/control group.</div></div><div><h3>Conclusions</h3><div>The analysis of the studies included in this review suggests a potential association between apical periodontitis and autoimmune diseases. However, it is important to consider that the selected studies have limitations, primarily because they are observational studies.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 562-570"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Novel Cryotherapy Technique on Postoperative Pain for Pulpotomy in Permanent Molars with Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial","authors":"Kübra Gürler DDS, Msc,&nbsp;Koray Yilmaz DDS, Msc","doi":"10.1016/j.joen.2025.01.020","DOIUrl":"10.1016/j.joen.2025.01.020","url":null,"abstract":"<div><h3>Introduction</h3><div>The purpose of this study was to evaluate the effect of cryotherapy application on postoperative pain in permanent molars with symptomatic irreversible pulpitis after full pulpotomy procedures.</div></div><div><h3>Methods</h3><div>Sixty-two patients with permanent maxillary and mandibular molars diagnosed with symptomatic irreversible pulpitis were included in the study. The teeth were randomly divided into 2 groups: the control group (<em>n</em> = 32) and the cryotherapy group (<em>n</em> = 30). In both groups, cotton pellets moistened with 2.5% sodium hypochlorite were used to achieve hemostasis. In the cryotherapy group, after hemostasis was achieved, the pulpotomy area was irrigated with saline solution at 2.5°C for 5 minutes. Then, in both groups, the pulp chamber was covered with Bio mineral trioxide aggregate+ (Cerkamed Company, Poland) and the composite restoration of the teeth (Clearfil Majesty Posterior, Kuraray Medical Inc., Tokyo, Japan) was completed. The participants were asked to rate the intensity of their postoperative pain via a Visual Analog Scale at 6, 12, 24, 48, and 72 hours. The data were analyzed using the Shapiro–Wilk, Levene's, Student t, Repeated Measures ANOVA and the Chi-square test.</div></div><div><h3>Results</h3><div>The basic demographic data and analgesic intake of the 2 study groups were similar. Compared with those in the control group, the postoperative pain scores at 6 and 12 hours were significantly lower in the cryotherapy group (<em>P</em> &lt; .05). The postoperative pain scores at 24, 48, and 72 hours were similar in both study groups.</div></div><div><h3>Conclusions</h3><div>During vital pulp treatment, the cryotherapy application after hemostasis reduced postoperative pain in permanent molars with symptomatic irreversible pulpitis in the early period.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 547-553"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Fibrous Area Ratio and Numbers of Cycles to Fracture Resistances of Nickel-Titanium Files","authors":"Hyeonu Jo DDS, MS ,&nbsp;Sang Won Kwak DDS, MS, PhD ,&nbsp;Asgeir Sigurdsson DDS, MS ,&nbsp;Hyeon-Cheol Kim DDS, MS, PhD","doi":"10.1016/j.joen.2025.02.004","DOIUrl":"10.1016/j.joen.2025.02.004","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to evaluate the correlation between the fibrous area ratio and the number of cycles to failure (NCF) in terms of fatigue fracture resistance of nickel-titaniumrotary files.</div></div><div><h3>Methods</h3><div>ProTaper Universal (PTU) and ProTaper Gold (PTG) files of size F2 (25 mm) were tested to make cyclic fatigue fracture using a custom-made device simulating a 35° canal curvature (<em>n</em> = 24). Using the fractured fragments, scanning electron microscopy was taken to analyze the fracture surfaces, focusing on fibrous areas on the cross-sections. Fibrous area ratios were calculated using ImageJ software, and NCF was determined by multiplying the time to fracture by rotational speed. Statistical analysis was performed to evaluate differences between groups and assess the correlation between fibrous area ratio and NCF (<em>P</em> &lt; .05).</div></div><div><h3>Results</h3><div>Scanning electron microscopy analysis revealed a higher fibrous area ratio in PTU files (<em>P</em> &lt; .05). The correlation analysis indicated a weak relationship between fibrous area ratio and NCF in both groups. PTG files demonstrated significantly higher NCF compared to PTU files (<em>P</em> &lt; .05). PTG group had a significantly lower fibrous area ratio than the PTU group (<em>P</em> &lt; .05).</div></div><div><h3>Conclusions</h3><div>While PTG files show improved cyclic fatigue resistance due to thermal processing, the fibrous area ratio is not a strong representing factor or predictor of NCF. Heat treatment influences the property of fracture resistance more significantly than propagation process of cyclic fatigue fracture.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 622-626"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical Configuration of the MB2 Canal Using High-Resolution Cone-Beam Computed Tomography","authors":"Luciana Magrin Blank-Gonçalves DDS, MSc ,&nbsp;Emmanuel João Nogueira Leal da Silva DDS, MSc, PhD ,&nbsp;Monikelly do Carmo Chagas Nascimento DDS, MSc, PhD ,&nbsp;Ana Grasiela Limoeiro DDS, MSc, PhD ,&nbsp;Luiz Roberto Coutinho Manhães-Jr DDS, MSc, PhD","doi":"10.1016/j.joen.2025.01.006","DOIUrl":"10.1016/j.joen.2025.01.006","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to evaluate the anatomical configuration of the mesiobuccal (MB) root of the maxillary first molar and to assess the prevalence of the second mesiobuccal canal (MB2).</div></div><div><h3>Methods</h3><div>A total of 307 high-resolution cone-beam computed tomography images of maxillary molars were analyzed. These images were classified based on the anatomical configuration and prevalence of the MB2 canal. An experienced evaluator examined the images by dynamically navigating through the entire tomographic volume, making necessary adjustments to the MB root in the axial, sagittal, and coronal planes along the canal trajectory. The anatomical configurations were classified according to Vertucci's classification.</div></div><div><h3>Results</h3><div>Overall, the prevalence of the MB2 canal within the sample was 90%. The most common anatomical configuration of the MB root was type IV (35%), followed by type VI (25%). MB roots with a single foramen were observed in 24% of the specimens, while 77% exhibited 2 foramina. No statistically significant differences were found between genders regarding prevalence and anatomical classifications (<em>P</em> &lt; .05).</div></div><div><h3>Conclusions</h3><div>The MB2 canal is highly prevalent, with the most common anatomical configuration being Vertucci's type IV, followed by type VI.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 609-615"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Wine Polyphenols on the Inflammatory Profile of Induced Apical Periodontitis in Rats","authors":"Rafaela Ricci MSc ,&nbsp;Bharbara de Moura Pereira MSc ,&nbsp;Julissa Denisse Arguello Alvarado DDS ,&nbsp;Romulo de Oliveira Sales-Junior MSc ,&nbsp;Nathália Evelyn da Silva Machado PhD ,&nbsp;Doany Cevada dos Santos DDS ,&nbsp;Felipe Haddad Martim Pederro DDS ,&nbsp;Marciane Magnani PhD ,&nbsp;Marcos dos Santos Lima PhD ,&nbsp;Edilson Ervolino PhD ,&nbsp;Luciano Tavares Ângelo Cintra PhD ,&nbsp;Anil Kishen PhD ,&nbsp;João Eduardo Gomes-Filho PhD","doi":"10.1016/j.joen.2025.01.023","DOIUrl":"10.1016/j.joen.2025.01.023","url":null,"abstract":"<div><h3>Introduction</h3><div>This study evaluated the impact of dealcoholized red wine polyphenols on the inflammation and lesion volume associated with apical periodontitis (AP) in rats.</div></div><div><h3>Methods</h3><div>Thirty-two Wistar rats receiving AP induction were arranged as follows: Control Group, Dealcoholized Red Wine Group (DRW), Red Wine Group, and Alcohol Group (ALC). Solutions were administered daily in a volume of 4.28 mL/kg via gavage for 45 days. Mandibles and maxillae were removed for histologic, immunohistochemical (IL-1β, IL-10, tumor necrosis factor-alpha, receptor activator of nuclear factor κB ligand, osteoprotegerin [OPG], and tartrate-resistant acid phosphatase), and micro-computed tomography analyses of the AP site. A statistical analysis was performed with a significance level of 5%.</div></div><div><h3>Results</h3><div>Inflammation and TRAP-positive cell count were similar for DRW and Red Wine Group, but lower when compared to Control Group and ALC (<em>P</em> &lt; .001). The immunohistochemical expression of OPG was higher for DRW than for ALC (<em>P</em> &lt; .05). A larger lesion volume was observed in ALC compared to other groups (<em>P</em> &lt; .001).</div></div><div><h3>Conclusions</h3><div>Prophylactic administration of dealcoholized red wine significantly reduced inflammation, decreased the number of TRAP-positive cells, enhanced OPG expression, and reduced lesion volume compared to water and alcohol solutions.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 594-601"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associate Registry","authors":"","doi":"10.1016/S0099-2399(25)00240-7","DOIUrl":"10.1016/S0099-2399(25)00240-7","url":null,"abstract":"","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 5","pages":"Pages 646-654"},"PeriodicalIF":3.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144084235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}