Catharina Anna Lammer , Mustafa Borga Dönmez , Gülce Çakmak , Çiğdem Kahveci , Burak Yilmaz
{"title":"Does ecologically sustainable printing and postprocessing enable dimensionally stable dental casts?","authors":"Catharina Anna Lammer , Mustafa Borga Dönmez , Gülce Çakmak , Çiğdem Kahveci , Burak Yilmaz","doi":"10.1016/j.jdent.2025.105908","DOIUrl":"10.1016/j.jdent.2025.105908","url":null,"abstract":"<div><h3>Objective</h3><div>To assess how resin type (water-washable [WW] and non-water-washable [NWW] and cleaning solution (water, methyl ether solvent [MES], or isopropyl alcohol [IPA]) affect the dimensional stability of additively manufactured casts over a three-month period.</div></div><div><h3>Methods</h3><div>Maxillary casts were fabricated using two WW (WW1 and WW2) and one NWW (NWW) cast resins (<em>N</em> = 24). These casts were divided into groups depending on the cleaning solution (water, MES, and IPA) used (<em>n</em> = 8), and digitized one day (T0), one week (T1), two weeks (T2), three weeks (T3), and three months (T4) after fabrication. Deviations were analyzed across regions (anterior, posterior, entire arch, soft tissue, and overall). A generalized linear model was used for statistical analysis (α = 0.05).</div></div><div><h3>Results</h3><div>NWW casts had the lowest anterior, posterior, and entire arch deviations (<em>P</em> < 0.001). WW1 casts mostly showed higher deviations than WW2 casts in these regions when cleaned with water or MES (<em>P</em> ≤ 0.028). WW1 casts had the highest soft tissue deviations within each cleaning solution (<em>P</em> < 0.001). With water, WW1 casts had higher deviations than with MES, while WW2 casts showed lower deviations than NWW casts (<em>P</em> ≤ 0.032). NWW resin or MES led to the lowest entire cast deviations, with the lowest values observed at T0 (<em>P</em> ≤ 0.007).</div></div><div><h3>Conclusions</h3><div>NWW casts mostly had the highest stability, while WW2 casts mostly had higher stability than WW1 casts. MES led to higher stability for WW resins and resulted in similar or higher stability for NWW resin compared to IPA.</div></div><div><h3>Clinical Significance</h3><div>Tested water-washable resins, particularly when cleaned with methyl ether solvent, may be sustainable alternatives to non-water-washable resin for dentate casts, as their deviations were acceptable for diagnostic and orthodontic purposes for three months. Methyl ether solvent can improve eco-friendliness of the fabrication of casts in tested non-water-washable resin.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105908"},"PeriodicalIF":4.8,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor Cavallaro Bottesini , Daniele Mara da Silva Ávila , Carlos Rocha Gomes Torres , Taís Scaramucci , Alessandra Bühler Borges
{"title":"Synergistic effect of aminomethacrylate copolymer and fluoride in toothpastes against erosive tooth wear","authors":"Victor Cavallaro Bottesini , Daniele Mara da Silva Ávila , Carlos Rocha Gomes Torres , Taís Scaramucci , Alessandra Bühler Borges","doi":"10.1016/j.jdent.2025.105904","DOIUrl":"10.1016/j.jdent.2025.105904","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the protective potential of fluoride toothpaste formulations associated with aminomethacrylate copolymer (AMC) against enamel initial erosion and erosive tooth wear.</div></div><div><h3>Material and Methods</h3><div>Polished bovine enamel specimens were divided into six groups (<em>n</em> = 13): placebo toothpaste (PL), AMC toothpaste (AMC 4 %), sodium fluoride toothpaste (F, 1450 ppm F<sup>-</sup>), AMC+NaF toothpaste (AMC+<em>F</em>), abrasion negative control (ANC - ultrapure water with abrasion), and erosion negative control- (ENC - ultrapure water without abrasion). Specimens underwent erosive/abrasive cycling, which included 0.3 % citric acid exposure (pH 2.69, 5 min, 4x/day), treatments (2x/day: brushing 15 s, and slurry 105 s), with immersion in human saliva in the intermediate periods (1 h). Knoop microhardness was assessed at baseline, after the first acid challenge, after the first treatment, and after the second acid challenge, allowing the calculation of rehardening ( %<em>Re</em>) and protective potential ( %Prot) of the treatments. After 5 days of cycling, surface loss (SL) was measured using profilometry. KOH-soluble fluoride was also quantified. Data were analyzed by one-way ANOVA and Tukey’s test (5 %).</div></div><div><h3>Results</h3><div>The AMC+<em>F</em> group showed significantly higher %<em>Re</em> and %Prot values compared to all other groups (<em>p</em> < 0.05). SL data (Mean ± SD) were: ENC (7.46±2.26)a, ANC (10.14±2.08)ab, PL (13.11±2.69)c, AMC (7.74±2.10)a, F (11.38±2.07)bc, AMC+<em>F</em> (7.52±2.59)a. KOH-soluble fluoride did not differ significantly in fluoride-containing groups (<em>p</em> = 0.001).</div></div><div><h3>Conclusion</h3><div>The addition of aminomethacrylate copolymer to a toothpaste formula enhanced the protective effect of sodium fluoride against initial erosion and erosive tooth wear.</div></div><div><h3>Clinical Significance</h3><div>Aminomethacrylate reduced enamel erosion and it enhanced fluoride’s protective effect, showing potential as an agent for effective control of erosive tooth wear.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105904"},"PeriodicalIF":4.8,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yaxu Feng , Brian E. Bergeron , Shijin Zhang , Danyang Sun , Kole Fisher , Franklin R. Tay , Bing Fan
{"title":"Apical negative pressure-enhanced sealer infiltration for obturating long oval-shaped root canals with the single-cone technique","authors":"Yaxu Feng , Brian E. Bergeron , Shijin Zhang , Danyang Sun , Kole Fisher , Franklin R. Tay , Bing Fan","doi":"10.1016/j.jdent.2025.105909","DOIUrl":"10.1016/j.jdent.2025.105909","url":null,"abstract":"<div><h3>Objectives</h3><div>This study evaluated the effect of apical negative pressure sealer infiltration on void percentage, void types, porosity size distribution, and coronal microleakage in root canal fillings using different hydraulic calcium silicate sealers with the single-cone technique.</div></div><div><h3>Methods</h3><div>Forty-eight extracted premolars with long oval-shaped canals were selected and divided into four groups based on the filling technique and sealer (<em>n</em> = 12): apical negative pressure-assisted NeoSEALER Flo (NPNF), apical negative pressure-assisted iRoot SP (NPS), syringe-assisted NeoSEALER Flo (SNF), and syringe-assisted iRoot SP (SS), all using the single-cone technique. Micro-computed tomography (10 µm resolution) was used to scan the obturated canals. Void percentages, types, and porosity size distribution were analyzed. Statistical significance was set at α = 0.05.</div></div><div><h3>Results</h3><div>None of the techniques yielded void-free obturations. However, the NPNF (0.75 %, interquartile range 0.93 %) and NPS (0.42 %, IQR 0.68 %) groups showed significantly lower overall void percentages than the SNF (13.27 %, IQR 9.24 %) and SS (15.39 %, IQR 13.87 %) groups (<em>p</em> < 0.05). No significant difference was identified between the NPNF and NPS groups, or between the SNF and SS groups. Apical negative pressure groups also demonstrated significantly fewer open voids and large porosities and reduced microleakage compared to the syringe-assisted groups (<em>p</em> < 0.05).</div></div><div><h3>Conclusion</h3><div>Apical negative pressure sealer infiltration combined with the single-cone technique significantly improved filling quality and reduced coronal microleakage in long oval-shaped root canals compared to the conventional syringe-assisted single-cone technique.</div></div><div><h3>Clinical.significance</h3><div>The use of apical negative pressure for introducing hydraulic calcium silicate sealers during single-cone obturation improves the quality of root canal fillings by reducing the percentage of voids and the presence of large porosities.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105909"},"PeriodicalIF":4.8,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitor Henrique Digmayer Romero , Júlia Macluf Torres , Eduardo Trota Chaves , Alice Caldeira Francioni Lang , Ana Clara Fazenda Araújo , Bárbara Canuto Sampaio , Camila Santin Silva , Carla Juliane Vegner , Françoise Hèléne van de Sande , Anelise Fernandes Montagner , Maximiliano Sérgio Cenci
{"title":"Comparison of treatment times for repair and replacement: A cross-sectional study","authors":"Vitor Henrique Digmayer Romero , Júlia Macluf Torres , Eduardo Trota Chaves , Alice Caldeira Francioni Lang , Ana Clara Fazenda Araújo , Bárbara Canuto Sampaio , Camila Santin Silva , Carla Juliane Vegner , Françoise Hèléne van de Sande , Anelise Fernandes Montagner , Maximiliano Sérgio Cenci","doi":"10.1016/j.jdent.2025.105907","DOIUrl":"10.1016/j.jdent.2025.105907","url":null,"abstract":"<div><h3>Objective</h3><div>This cross-sectional study analyzed and compared the treatment time for dental students to perform different restorative procedures (repair or replacement).</div></div><div><h3>Material and methods</h3><div>This study used secondary data from patients treated in a randomized controlled trial (CaCIA). The time (in minutes) was monitored by the operators/assistants, performed between 2016 and 2022. The operator's level during the procedures was categorized into third, fourth, and fifth years. Since procedure times were not normally distributed, non-parametric tests were applied: Mann-Whitney U for two-group comparisons (repair × replacement) and Kruskal–Wallis for comparisons across student years, followed by Bonferroni-adjusted pairwise Mann-Whitney tests when <em>p</em> < 0.05; 95 % confidence intervals for means were also calculated.</div></div><div><h3>Results</h3><div>A total of 117 procedures were analyzed: 76 repairs (mean 110.2 ± 29.4 min) and 41 replacements (mean 128.4 ± 30.9 min). Repairs in molars averaged 109.2 ± 32.0 min, while replacements in molars averaged 130.9 ± 34.4 min, showing a significant difference (<em>p</em> = 0.015). Repairs averaged 112.2 ± 23.8 min for premolars, while replacements averaged 122.5 ± 20.1 min, with no significant difference observed (<em>p</em> = 0.248). Comparisons between third, fourth, and fifth student groups demonstrated significant differences in repair (<em>p</em> = 0.001) and replacement (<em>p</em> = 0.012) times, with final year students completing procedures faster.</div></div><div><h3>Conclusion</h3><div>Repairs require significantly less time than replacements, particularly for molars. Additionally, the variation in time required by students from different academic levels underscores the relevance of technical skills and experience in reducing procedural duration.</div></div><div><h3>Clinical relevance</h3><div>This study highlights the clinical advantages of repair over replacement in restorative dentistry, particularly regarding time efficiency. Repairs not only require less time than replacements, especially for molars, but also align with the principles of minimally invasive dentistry by preserving tooth structure.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105907"},"PeriodicalIF":4.8,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolina Bender Hoppe , Pauline Mastella Lang , Lara Dotto , Roberta Kochenborger Scarparo , Matheus Silveira Martins Hartmann , Maximiliano Schunke Gomes , Fabiana Soares Grecca
{"title":"Pre and intraoperative factors impact on periapical healing of endodontically treated molars: a multicentric observational study","authors":"Carolina Bender Hoppe , Pauline Mastella Lang , Lara Dotto , Roberta Kochenborger Scarparo , Matheus Silveira Martins Hartmann , Maximiliano Schunke Gomes , Fabiana Soares Grecca","doi":"10.1016/j.jdent.2025.105903","DOIUrl":"10.1016/j.jdent.2025.105903","url":null,"abstract":"<div><h3>Introduction</h3><div>Pre and intraoperative clinical variables of endodontic procedures are diverse among operators and schools, which may adopt different guidelines. Thus, it is challenging to establish comparisons regarding differences which can potentially influence the desired periapical healing. Thus, this study aimed to evaluate the influence of operative factors on the clinical and radiographic success of root canal treatment between two postgraduation centers.</div></div><div><h3>Methods</h3><div>The treatment outcome of 134 molars was assessed. Besides preoperative data, variations between treatment protocols were also collected. The root canal treatment was classified as ‘success’ or ‘failure' according to the Periapical Index score. Participants were followed-up for up to 48 months. Bi and multivariate models, using Poisson regression with robust variance, were used.</div></div><div><h3>Results</h3><div>The overall success rate of the root canal treatment was 79.9 %. Preoperative apical periodontitis was significantly associated with a poorer success rate (<em>P</em> = 0.007) of 71.6 % whereas when apical periodontitis was absent, the success rate raised to 90 %. The strength of this association was held even when the model is adjusted for age, sex, treatment protocol, tooth location, obturation level, and recall period. Hydraulic vertical condensation filling technique was associated with a 4-fold rate of overextension (<em>P</em> < 0.001). None of the other technical variables affected the outcome of endodontic treatment.</div></div><div><h3>Conclusion</h3><div>The presence of apical periodontitis is highly associated with worse endodontic prognostic, despite the guideline adopted by the postgraduation center.</div></div><div><h3>Clinical relevance</h3><div>Meaningful further development and research must provide innovative tools and techniques for endodontists, focusing mainly on anatomical complexity challenges. In this sense, a substantial increase in endodontic success rates in high complexity teeth treatment, such as molars, could be expected.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105903"},"PeriodicalIF":4.8,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seppe Bleyen , Kelly Mooens , Luka Jancic , Paul Lambrechts , Nastaran Meschi , Mariano S. Pedano
{"title":"Virtual reality for patients with dental anxiety: A scoping review","authors":"Seppe Bleyen , Kelly Mooens , Luka Jancic , Paul Lambrechts , Nastaran Meschi , Mariano S. Pedano","doi":"10.1016/j.jdent.2025.105905","DOIUrl":"10.1016/j.jdent.2025.105905","url":null,"abstract":"<div><h3>Objective</h3><div>This scoping review aimed to examine the literature regarding the use of virtual reality (VR) to reduce pain and anxiety before or during dental procedures.</div></div><div><h3>Methods</h3><div>A review of studies published between 2000 and 2024 was conducted, using PubMed and Embase databases. Eligible studies involved healthy patients (ASA I and II) with dental anxiety undergoing dental procedures using VR.</div></div><div><h3>Results</h3><div>A total of 46 studies were included, covering pediatric dentistry, oral surgery, periodontics and endodontics. 31 studies found that VR glasses significantly reduced pain and anxiety during dental treatment. VR was useful for managing children's behavior during dental procedures. Some studies reported improvements in blood pressure and heart rate. While most studies found a significant reduction in anxiety and pain, a few showed non-significant changes. VR was generally well-received by patients, with mild adverse effects such as nausea or claustrophobia.</div></div><div><h3>Conclusion</h3><div>VR appears to be an effective tool for managing dental anxiety in various dental fields, but research is still limited, particularly in adults. Most studies involved children, showing positive results in reducing anxiety, pain, time perception, blood pressure, pulse rate, and salivary cortisol levels. However, further research is needed to fully evaluate the role of VR in endodontic treatments and the effectiveness of VR treatment in adult patients.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105905"},"PeriodicalIF":4.8,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jenni Hjerppe , Alexis Ioannidis , Ana María Valdés , Daniel S. Thoma , Ronald E. Jung , Cristián Manuel Bravo Palma , Sven Mühlemann
{"title":"Posterior monolithic 3-unit zirconia fixed dental prostheses: one-year interim results of a multicenter randomized clinical trial","authors":"Jenni Hjerppe , Alexis Ioannidis , Ana María Valdés , Daniel S. Thoma , Ronald E. Jung , Cristián Manuel Bravo Palma , Sven Mühlemann","doi":"10.1016/j.jdent.2025.105900","DOIUrl":"10.1016/j.jdent.2025.105900","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare the survival rates and clinical outcomes of posterior 3-unit monolithic zirconia fixed dental prostheses (FDPs) to veneered zirconia FDPs.</div></div><div><h3>Methods</h3><div>Sixty-four patients missing single teeth in the posterior mandible or maxilla were recruited. Patients’ restorations were randomly allocated to three groups: 1) monolithic zirconia FDPs (Mono-FDP, <em>n</em> = 21); 2) partially veneered zirconia FDPs (PV-FDP, <em>n</em> = 21); 3) circumferentially veneered zirconia FDPs (V-FDP, <em>n</em> = 22). Technical complications were evaluated by modified United States Public Health Service (USPHS) criteria at one-year follow-up appointments. Radiographs, clinical parameters including probing pocket depths (PD), bleeding on probing (BOP), plaque index (PI) and patient-reported outcome measures (PROMs) of prostheses and patients were evaluated at baseline and one-year follow-up appointments. The results were evaluated descriptively.</div></div><div><h3>Results</h3><div>Sixty-two patients were available for re-examination, two patients in PV-FDP group were lost to follow-up. At one-year follow-up, no FDPs were lost. Technical complication rates, namely small fractures were 0 % in the mono-FDPs, 9.5 % (2) in PV-FDPs and 22.7 % (5) in V-FDPs. USPHS rating A for patient satisfaction (PROMs) was given to 85.7 % (18) of Mono-FDPs, 85.7 % (18) of PV-FDPs and 90.9 % (20) of V-FDPs revealing high patient satisfaction with FPDs in all the groups at one year.</div></div><div><h3>Conclusions</h3><div>According to the one-year interim results of this clinical study of the posterior tooth-supported FDPs, monolithic zirconia FDPs seem to show no technical complications whereas the veneered zirconia FDPs exhibited veneering porcelain chippings. Survival and biologic outcomes were excellent in all the study groups.</div></div><div><h3>Clinical significance</h3><div>The present one-year interim results show that veneered, partially veneered and monolithic FDPs can be used with good confidence, however, FDPs with veneering ceramic might exhibit ceramic chippings.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105900"},"PeriodicalIF":4.8,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronnie Ruonan Zhang, Josie Shizhen Zhang, Shi Huang, Walter Yu-Hang Lam, Chun-Hung Chu, Ollie Yiru Yu
{"title":"The oral microbiome of root caries: A scoping review","authors":"Ronnie Ruonan Zhang, Josie Shizhen Zhang, Shi Huang, Walter Yu-Hang Lam, Chun-Hung Chu, Ollie Yiru Yu","doi":"10.1016/j.jdent.2025.105899","DOIUrl":"10.1016/j.jdent.2025.105899","url":null,"abstract":"<div><h3>Objective</h3><div>This review characterizes shifts of the oral microbial community on carious root surfaces compared to sound root surfaces.</div></div><div><h3>Data and sources</h3><div>A systematic search of English-language publications on clinical studies evaluating oral microbiomes in patients with root caries using high-throughput sequencing technologies published before April 1, 2025, was included. The search was conducted on PubMed, Cochrane Central Register of Controlled Trials, Web of Science, Embase, and Scopus. Gray literature was searched in ClinicalTrials.gov and Google Scholar.</div></div><div><h3>Study selection/Results</h3><div>Based on the eligibility criteria, 1133 publications were screened, and 465 duplicates were removed. Of the remaining 16 studies assessed for full-text review, eight investigating the oral microbiome of saliva, carious roots, or dental plaque in patients with root caries were included. These studies reported the intra-community species diversity (alpha-diversity, 4/8 studies), inter-community compositional diversity (beta-diversity, 4/8 studies), dominant microbial genera/species (8/8 studies), and functional pathways (1/8 studies) of the microbial community in root caries patients. Alpha-diversity showed no significant difference between root caries and sound root surfaces in three studies, but root caries exhibited a significantly lower alpha diversity in one study. Beta-diversity differed significantly between root caries and sound root surfaces in three studies, with one study reporting no difference. The dominant microbial species in root caries varied among the included studies. However, <em>Lactobacillus</em> spp., <em>Prevotella denticola, Propionibacterium acidifaciens, Streptococcus mutans</em>, and <em>Veillonella parvula/dispar</em> were frequently identified in the root caries-associated microbiota. Furthermore, root caries-associated bacteria altered the predicted functional pathways, promoting organic acid production and accelerating collagen degradation.</div></div><div><h3>Conclusion</h3><div>Root caries microbiomes exhibit distinct compositional profiles, dysbiotic species predominance, and a shift in predicted functional pathways compared to healthy root surfaces.</div></div><div><h3>Clinical significance</h3><div>This review provides valuable insights into root caries’ microbial landscape, potentially guiding future preventative and therapeutic strategies.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105899"},"PeriodicalIF":4.8,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcelle Danelon , Gabriel Pereira Nunes , Torsten Sterzenbach , Christian Hannig
{"title":"Enhancing antimicrobial properties of glass ionomer cement through metallic agent reinforcement: A systematic review and meta-analysis","authors":"Marcelle Danelon , Gabriel Pereira Nunes , Torsten Sterzenbach , Christian Hannig","doi":"10.1016/j.jdent.2025.105892","DOIUrl":"10.1016/j.jdent.2025.105892","url":null,"abstract":"<div><h3>Objectives</h3><div>This systematic review and meta-analysis (SRM) aimed to assess the impact of incorporating metallic agents into glass ionomer cement (GIC) and resin-modified glass ionomer cement (RMGIC) on their microbiological properties and antibacterial activity.</div></div><div><h3>Data sources</h3><div>Following PRISMA guidelines, the SRM included studies published up to August 21, 2024.</div></div><div><h3>Study selection</h3><div>The eligibility criteria included clinical trials, <em>in situ</em>, and <em>in vitro</em> studies. The data were analyzed using RevMan software, and bias risk was assessed with the Joanna Briggs Institute’s Checklist for <em>in vitro</em> studies and the ROBINS-I tool for clinical trials.</div></div><div><h3>Results</h3><div>Out of 2,393 screened records, 32 studies were included. Results showed that metallic agents like silver, zinc oxide, titanium dioxide, and copper enhanced the antimicrobial properties of GIC and RMGIC. Most studies reported superior antimicrobial effects compared to controls, with only two studies showing neutral effects. Meta-analysis revealed that GIC with 5 % TiO₂ or 2 % ZnO nanoparticles significantly reduced <em>S. mutans</em> viability, while silver zeolite at 1 % and 5 % concentrations showed strong effects. Similarly, adding silver or ZnO to RMGIC improved its activity against <em>S. mutans</em> and <em>L. acidophilus</em>. The studies showed a low risk of bias.</div></div><div><h3>Conclusions</h3><div>Metallic agents enhance the antimicrobial efficacy of GIC/RMGIC, offering a promising solution for biofilm control in dental restorations. However, further research is needed to optimize their clinical application, particularly through in vivo studies, and to assess their impact on mechanical, esthetic, and cytotoxic properties.</div></div><div><h3>Clinical relevance</h3><div>Incorporating metallic agents into GIC and RMGIC enhances their antibacterial properties, improving biofilm control in dental restorations. This modification may reduce the risk of secondary caries and prolong restoration longevity.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105892"},"PeriodicalIF":4.8,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paniz Hobbi , Tugce Merve Ordueri , Funda Öztürk-Bozkurt , Tugba Toz-Akalın , Mehmet Muzaffer Ateş , Mutlu Özcan
{"title":"Assessing the performance of 3D-printed resin composite posterior fixed dental prostheses: A 3-year prospective clinical trial","authors":"Paniz Hobbi , Tugce Merve Ordueri , Funda Öztürk-Bozkurt , Tugba Toz-Akalın , Mehmet Muzaffer Ateş , Mutlu Özcan","doi":"10.1016/j.jdent.2025.105887","DOIUrl":"10.1016/j.jdent.2025.105887","url":null,"abstract":"<div><h3>Objectives</h3><div>This clinical trial aimed to assess the clinical performance of 3D-printed resin composite fixed dental prostheses (FDPs) for posterior restorations.</div></div><div><h3>Methods</h3><div>From October 10, 2020, to August 5, 2022, a total of 49 patients (33 females and 16 males), aged 19 to 60, were treated with 68 three-unit 3D-printed resin composite posterior FDPs (ELS Even Stronger, Saremco, Switzerland). Two weeks after placement, the FDPs were evaluated by two independent observers using modified FDI criteria. Parameters assessed included anatomical form, secondary caries, marginal adaptation, surface roughness, color match, material fracture, surface staining, margin staining, anatomical form, retention, gingival health, and patient satisfaction. Failures were classified as either mechanical or biological.</div></div><div><h3>Results</h3><div>The mean observation period was 22.36 months. At the final recall, of the 64 FDPs, 24 remained in clinical service without any complications, indicating limited long-term success. Almost all restorations maintained normal anatomical contours throughout the follow-up period. During the initial six-month period, 9 instances of fractures were identified, followed by 14 after 1 year, 11 after two-year a further 2 cases after a three-year period of clinical service. Of the 40 failed FDPs, 36 exhibited mechanical failures, while 6 showed biological failures (2 cases exhibited both and were counted in both categories). Thirty-four FDPs showed cohesive fractures. Two FDPs were re-bonded, four abutment teeth required endodontic treatment, and two presented periodontal issues. Additionally, 2 FDPs exhibited a loss of surface luster, 4 exhibited color mismatches, and 4 exhibited surface staining (all scored 4). Kaplan-Meier analysis revealed a 40.7 % survival rate for mechanical failures and a 36.2 % survival rate when biological complications were included.</div></div><div><h3>Conclusions</h3><div>The results of a three-year follow-up study indicated that 3D-printed resin composite FDPs present failures mainly in the connector region, suggesting the need for further design improvements.</div></div><div><h3>Clinical Significance</h3><div>Three-dimensionally printed resin composite FDPs offer certain advantages but current restorations could be considered as long-term provisional due to the incidence of mainly mechanical failures up to 3 years.</div></div><div><h3>Clinical Trial Registration</h3><div>Clinical Trials.Gov, NCT04600297.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105887"},"PeriodicalIF":4.8,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}