Joon Soo Park , Yosef Faraj Amer Alshehri , Estie Kruger , Luke Villata
{"title":"Accuracy of digital versus conventional implant impressions in partially dentate patients: A systematic review and meta-analysis","authors":"Joon Soo Park , Yosef Faraj Amer Alshehri , Estie Kruger , Luke Villata","doi":"10.1016/j.jdent.2025.105918","DOIUrl":"10.1016/j.jdent.2025.105918","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare the accuracy of digital and conventional impression techniques in partially dentate patients undergoing implant-supported prosthodontic treatment. The primary focus was three-dimensional accuracy, including angular and linear deviations, inter-implant distances, and scan-body misfit.</div></div><div><h3>Data</h3><div>Data were extracted from seven clinical studies involving 151 partially dentate patients. Only three studies contributed data to the angular displacement meta-analysis, and four studies to the deviation analysis. The studies included randomised controlled trials and non-randomised clinical investigations comparing intraoral scanner (IOS)-based digital impressions with conventional impressions using polyvinyl siloxane or polyether materials.</div></div><div><h3>Sources</h3><div>A systematic search was conducted in March 2025 across five databases: PubMed, EMBASE, Web of Science, CINAHL, and the Cochrane Library. PRISMA 2020 guidelines conducted the review and were prospectively registered with PROSPERO (CRD420251006999) and the International Platform of Registered Systematic Review and Meta-analysis Protocols (INPLASY202530032).</div></div><div><h3>Study selection</h3><div>Eligible studies were those that clinically assessed impression accuracy in partially dentate implant patients using either digital or conventional methods. Studies were included if they reported quantitative measures of impression accuracy. <em>In vitro</em> studies, non-implant restorative comparisons, and fully edentulous patient cohorts were excluded.</div></div><div><h3>Conclusions</h3><div>Digital impressions demonstrated significantly lower deviation than conventional impressions, indicating superior spatial accuracy in certain clinical settings. However, no significant difference was observed in angular displacement. Considerable heterogeneity (I² = 80–97 %) across studies limits the certainty of pooled outcomes. Digital impressions are a clinically acceptable alternative for short-span implant restorations in partially dentate patients, though caution is warranted in cases involving long-span or angulated implants. Further high-quality clinical trials with standardised protocols are needed to support broader clinical adoption.</div></div><div><h3>Clinical importance</h3><div>Digital impressions are a clinically acceptable alternative to conventional methods in partially dentate patients. Nevertheless, clinicians should exercise caution in long-span restorations or angulated implants until further high-quality studies with standardised protocols and long-term data are available.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105918"},"PeriodicalIF":4.8,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bree Jones , Mathias Lambach , Tong Chen , Stavroula Michou , Nicky Kilpatrick , Nigel Curtis , David P. Burgner , Christoph Vannahme , Mihiri Silva
{"title":"Dental caries detection in children using intraoral scans and deep learning","authors":"Bree Jones , Mathias Lambach , Tong Chen , Stavroula Michou , Nicky Kilpatrick , Nigel Curtis , David P. Burgner , Christoph Vannahme , Mihiri Silva","doi":"10.1016/j.jdent.2025.105906","DOIUrl":"10.1016/j.jdent.2025.105906","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to demonstrate the use of deep learning for automating caries detection using intraoral scan data from children and to evaluate diagnostic agreement between the models’ predictions and dental practitioner assessments on 3D models.</div></div><div><h3>Methods</h3><div>Intraoral scans were collected from two cohorts at Murdoch Children’s Research Institute. Two researchers annotated scan meshes using the International Caries Classification and Management System. A pre-processing pipeline converted the data into a 2D format. Carious teeth from the first cohort (<em>n</em> = 332) were split at the participant level into training (<em>n</em> = 192), validation (<em>n</em> = 63), and test (<em>n</em> = 77) sets. An Attention U-Net was trained to classify initial, moderate, and extensive dental caries. Segmentation and lesion detection performance was evaluated on the test set using the metrics Intersection over Union (IoU), Sensitivity (SE), Specificity (SP), and Precision (P). Carious teeth from the second independent cohort (<em>n</em> = 119) were used for external validation. Multilevel logistic regression assessed diagnostic agreement to compare the model performance to dental practitioners across all caries thresholds (initial, moderate and extensive).</div></div><div><h3>Results</h3><div>For segmentation tasks, the model had the best performance for extensive caries (SE 71 %, P 66 %, IOU 0.55). The model showed overall promising performance for lesion detection (SE 67 %, P 73 %). Performance slightly declined on an external dataset. Diagnostic agreement between the model and dental practitioners was comparable across all disease thresholds: initial (odds ratio OR 0.82, 95 % Confidence Interval (CI) 0.6–1.15), moderate (OR 0.9, 95 % CI 0.5–1.6) and extensive (OR 0.85, 95 % CI 0.42–1.71).</div></div><div><h3>Conclusion</h3><div>The proof-of-concept demonstrates that deep learning can achieve moderate performance in detecting extensive caries from intraoral scans, though performance was limited for early and moderate lesions. Further research is needed to improve model accuracy and generalisability across all disease stages.</div></div><div><h3>Clinical Significance</h3><div>This study represents an exploratory effort towards developing AI-assisted caries detection using intraoral scanner data in children. While the long-term potential of such technology could include support for early diagnosis, enhanced caries monitoring, and a reduction in the subjectivity of caries assessment, our current findings indicate that significant model refinement and extensive validation are imperative, especially for the detection of initial carious lesions, before such clinical applications can be realized.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105906"},"PeriodicalIF":4.8,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Amalgam alternatives: Susceptibility of novel self-adhesive materials to changes in dentin mineralization","authors":"Vasil Christoff, Nicoleta Ilie","doi":"10.1016/j.jdent.2025.105894","DOIUrl":"10.1016/j.jdent.2025.105894","url":null,"abstract":"<div><div>Objectives: This study explores the effects of artificial de- and hypermineralization on the shear bond strength (SBS) of three innovative dental materials: a modern ion – releasing resin–based composite (Cention Forte (CF)), a resin-modified glass ionomer cement (Surefil One (SO)), and a high-viscosity glass ionomer cement (Equia Forte (EF)), all tested on human dentin. Methods: A total of 360 human dentin specimens were divided into 18 groups (<em>n</em> = 20). Each material was bonded to either healthy, hypermineralized, or demineralized dentin. After aging at 37 °C in distilled water for 1 week and artificial saliva for 6 months, SBS was tested following ISO 29,022. Fracture origins and patterns were analyzed via light microscopy. Results: The SBS values of EF on hyper- and demineralized dentin were lower after 1 week and 6 months when compared to sound dentin, whereas for CF this trend was only seen on demineralized dentin after 1 week. Regardless of aging, the SBS values of SO displayed no significant difference in comparison to the reference. Across all substrates and aging types, the SBS values of CF were the highest. The long-term bond reliability of CF and EF on sound dentin was similar, as was the bond reliability of CF and SO on hypermineralized dentin. Conclusions: CF produces the strongest bond to dentin irrespective of dentin substrate or aging. Demineralization deteriorates the bond strength of both CF and EF, whereas hypermineralization only that of EF. SO remains unaffected by changes in dentin mineralization, enabling it to form stronger bonds to hypermineralized dentin than EF. Clinical Significance: A proper assessment of a material's bond strength to dentin substrates with varying degrees of mineralization is crucial for evaluating its potential as an effective amalgam replacement, capable of forming reliable bonds across a broad range of tooth substrates</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105894"},"PeriodicalIF":4.8,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144288719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R.J. Wierichs , T.T. Werren , L. Jaruszewski , H. Meyer-Lueckel
{"title":"Vertical reflection intensity, roughness, and tactile sensation of caries-inactive, caries-active and sound enamel surfaces: an in vitro study","authors":"R.J. Wierichs , T.T. Werren , L. Jaruszewski , H. Meyer-Lueckel","doi":"10.1016/j.jdent.2025.105915","DOIUrl":"10.1016/j.jdent.2025.105915","url":null,"abstract":"<div><h3>Objectives</h3><div>This study evaluated whether reflection intensity, roughness and tactile sensation differs between caries-inactive, caries-active and sound enamel surfaces.</div></div><div><h3>Methods</h3><div>Pooled permanent teeth were assessed using surface texture and color. Teeth with caries-inactive (C<sub>i</sub>, <em>n</em> = 55), caries-active (C<sub>a</sub>, <em>n</em> = 59) and sound (S, <em>n</em> = 13) vestibular or proximal surfaces were selected. Vertical reflection intensity (VRI) and roughness parameters, including mean linear (Ra), area-related (Sa) and volume-related (Vmc) of C<sub>i</sub>, C<sub>a</sub> and S were assessed using a multi-sensor microscope (MicroProf®100,FRT GmbH) with a conventional or an experimental handheld chromatic-confocal optic and a 3D-laser-scanning-microscope (VK-X110,Keyence). VRI and roughness values for caries-active surfaces were obtained from a previous study, while blinded tactile assessment for these surfaces was repeated. Two experienced examiners evaluated the tactile sensation using two explorers (405/CP11, S23H) (<em>n</em> = 20).</div></div><div><h3>Results</h3><div>For all roughness parameters significant differences between caries surfaces and adjacent sound surfaces on the same teeth could be observed (<em>p</em> ≤ 0.029, Wilcoxon). For VRI significant differences were only observed for caries-active surfaces (<em>p</em> < 0.001). Across C<sub>i</sub>, C<sub>a</sub> and S significant difference could be observed for all roughness parameters (<em>p</em> ≤ 0.012, Bonferroni) and VRI (<em>p</em> < 0.001), except for VRI between C<sub>i</sub> and S (<em>p</em> ≥ 0.390). No significant difference in VRI was observed between both optics (<em>p</em> > 0.05, Bonferroni). The positive predictive value (PPV) differed between examiner 1 (S23H: C<sub>i</sub>:30 %; C<sub>a</sub>:83 %; S:97 %, 405CP11: C<sub>i</sub>:27 %; C<sub>a</sub>:74 %; S:91 %) and examiner 2 (S23H: C<sub>i</sub>:20 %; C<sub>a</sub>:72 %; S:84 %, 405CP11: C<sub>i</sub>:23 %; C<sub>a</sub>:68 %;S; 85 %).</div></div><div><h3>Conclusion</h3><div>Optical measurement and tactile methods revealed significant differences between active, inactive, and sound enamel surfaces. However, the diagnostic accuracy varied between explorers and examiners.</div></div><div><h3>Clinical significance</h3><div>Active, inactive, and sound enamel surfaces showed significant differences in roughness and reflection intensity. While both optical methods are not yet applicable intraorally, tactile assessment showed strong variabilities between examiners and dependence on the type of dental explorer used, especially when simulating non-visible areas.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105915"},"PeriodicalIF":4.8,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabella Neme Ribeiro dos Reis , Aldrin André Huamán-Mendoza , Dania Ramadan , Heitor Marques Honório , Nadja Naenni , Giuseppe Alexandre Romito , Marinella Holzhausen , Claudio Mendes Pannuti
{"title":"The prevalence of peri-implant mucositis and peri-implantitis based on the world workshop criteria: A systematic review and meta-analysis","authors":"Isabella Neme Ribeiro dos Reis , Aldrin André Huamán-Mendoza , Dania Ramadan , Heitor Marques Honório , Nadja Naenni , Giuseppe Alexandre Romito , Marinella Holzhausen , Claudio Mendes Pannuti","doi":"10.1016/j.jdent.2025.105914","DOIUrl":"10.1016/j.jdent.2025.105914","url":null,"abstract":"<div><h3>Objectives</h3><div>This systematic review and meta-analysis aimed to estimate the worldwide prevalence of peri-implant mucositis and peri-implantitis using the 2017 World Workshop criteria.</div></div><div><h3>Data and sources</h3><div>A comprehensive electronic search was performed in MEDLINE/PubMed, SCOPUS, EMBASE, and Web of Science databases. Cross-sectional studies assessing the prevalence of peri-implant diseases according to the 2017 Classification of Periodontal and Peri-Implant Diseases and Conditions classification were included. The risk of bias was assessed according to the Joanna Briggs Institute Critical Appraisal tool for Studies Reporting Prevalence Data. A mixed-effects model meta-analysis was performed.</div></div><div><h3>Study selection</h3><div>Twenty out of 1979 studies were included. The weighted mean prevalence of peri-implant mucositis was 63.0 % (CI: 57.6–68.2 %) at the patient level and 59.2 % (CI: 55.8–62.4 %) at the implant level. Peri-implantitis was observed in 25.0 % (CI: 21.1–29.3 %) of patients and 18.0 % (CI: 15.8–20.5 %) of implants. Subgroup analyses revealed significant differences in the prevalence of peri-implant mucositis and peri-implantitis across continents. In non-smokers, the implant-level prevalence of peri-implant mucositis and peri-implantitis was 38.2 % (CI: 33.4–43.2 %) and 5.2 % (CI: 3.6–7.5 %), respectively. The risk of bias was high in 50 %, moderate in 45 %, and low in 5 % of the studies.</div></div><div><h3>Conclusions</h3><div>Based on the 2017 World Workshop criteria, the prevalence of peri-implant diseases represents a significant and growing public health challenge. Our study demonstrated that approximately two in three adults with dental implants had peri-implant mucositis, and one in four had peri-implantitis.</div></div><div><h3>Clinical significance</h3><div>This study is the first to provide robust global prevalence estimates for peri-implant diseases based on standardized 2017 World Workshop criteria. The findings highlight the high worldwide prevalence of peri-implant diseases, emphasizing the need for uniform diagnostic protocols and targeted prevention and treatment strategies.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105914"},"PeriodicalIF":4.8,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Willian Favoreto , Michel Wendlinger , Laryssa Mylenna Madruga Barbosa , Gabriel David Cochinski , Vinicius Borges Oliveira , Cesar Augusto Galvão Arrais , Alessandra Reis , Alessandro D. Loguercio
{"title":"Optimal photoactivation time and thermal behavior of gingival barriers used in in-office dental bleaching","authors":"Michael Willian Favoreto , Michel Wendlinger , Laryssa Mylenna Madruga Barbosa , Gabriel David Cochinski , Vinicius Borges Oliveira , Cesar Augusto Galvão Arrais , Alessandra Reis , Alessandro D. Loguercio","doi":"10.1016/j.jdent.2025.105888","DOIUrl":"10.1016/j.jdent.2025.105888","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the influence of exposure time and curing distance on the degree of conversion (DC) and temperature change of light-cured gingival barrier materials.</div></div><div><h3>Methods</h3><div>An in vitro study was conducted with 576 disk-shaped specimens, divided into 72 groups (<em>n</em> = 8) based on three factors: gingival barrier type (SDI Gingival barrier, DMC Lase Protect, Ultradent OpalDam, PHS Potenza Blocco, FGM Top Dam, DFL Total Blanc Protetor Gengival), irradiation time (3, 5, 10, 15, 20, and 30 s), and curing distance (Valo, Standard Mode: 1 mm [900 mW/cm²] or 10 mm [450 mW/cm²]). DC was assessed by micro-Raman spectroscopy. Thermal changes were assessed using a T-type thermocouple on simulation model. Light characteristics of the LED curing unit were determined using spectroradiometer and integrating sphere. Data were analyzed using ANOVA and Tukey’s test (α = 0.05).</div></div><div><h3>Results</h3><div>At 1 mm, the LED delivered 657.31 mW of power and 908.57 mW/cm² of irradiance; at 10 mm, the values were 326.25 mW and 450.95 mW/cm². Radiant exposure increased with time and was significantly higher at 1 mm (<em>p</em> < 0.01). Longer exposure improved DC, with significant variations among materials (<em>p</em> < 0.01). The highest DC (93 %) was achieved with 1 mm distance after 30 s. Temperature rise also varied by material and increased with irradiance and time (<em>p</em> < 0.01).</div></div><div><h3>Conclusions</h3><div>Gingival barrier polymerization is influenced by material type, curing distance, and exposure time. Most materials reached adequate conversion with 10 s at 1 mm. However, prolonged curing (30 s) led to temperature increases above 50 °C in some materials. At 10 mm, at least 20 s was required for safe and effective polymerization.</div></div><div><h3>Significance</h3><div>Gingival barriers should be light-cured for a minimum of 10 s at 1 mm. At 10 mm, exposure time should be extended to at least 20 s to ensure sufficient polymerization while minimizing thermal risk.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105888"},"PeriodicalIF":4.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giusy Rita Maria La Rosa , Cinzia Del Giovane , Silvia Minozzi , Jan Kowalski , Iain Chapple , Amaliya Amaliya , Konstantinos Farsalinos , Riccardo Polosa
{"title":"Oral health effects of non‑combustible nicotine products: a systematic review and network meta‑analysis of randomized controlled trials","authors":"Giusy Rita Maria La Rosa , Cinzia Del Giovane , Silvia Minozzi , Jan Kowalski , Iain Chapple , Amaliya Amaliya , Konstantinos Farsalinos , Riccardo Polosa","doi":"10.1016/j.jdent.2025.105910","DOIUrl":"10.1016/j.jdent.2025.105910","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the oral adverse effects of non-combustible nicotine products (NCNPs) compared with each other, placebo, standard of care, no treatment and combustible cigarettes through a systematic review and network meta-analysis.</div></div><div><h3>Data sources and study selection</h3><div>Randomized controlled trials involving adult smokers and reporting oral adverse events (e.g., mouth irritation, dry mouth, aphthous ulcers) were included. PubMed, Scopus, and Cochrane CENTRAL were searched up to August 2024. Risk of bias was assessed using RoB 2, and evidence certainty with CINeMA.</div></div><div><h3>Results</h3><div>Thirty-six trials were included, with 21 contributing to the network meta-analysis. Most comparisons with placebo showed no significant differences across four primary outcomes. The odds of developing aphthous ulcers were significantly higher in the nicotine replacement therapy (NRT) gum group compared with standard of care (OR = 2.36; 95 % CI: 1.05–5.30). Higher odds of mouth irritation were also observed for e-cig (OR = 4.06; 95 % CI: 1.67–9.85), NRT mouth spray (OR = 4.36; 95 % CI: 1.14–16.63), NRT gum (OR = 4.25; 95 % CI: 1.51–11.94) and snus (OR = 13.56; 95 % CI: 1.07–171.52) when compared with standard of care. Sensitivity analyses confirmed the main findings. Secondary outcomes revealed isolated associations but were based on limited data. Evidence certainty was low to very low due mainly to imprecision and risk of bias.</div></div><div><h3>Conclusions</h3><div>NCNPs appear to be generally well tolerated. Most placebo comparisons showed no increased risk, although some products exhibited higher odds of aphthous ulcers and mouth irritation compared with standard of care. Better reporting of oral adverse events in RCTs is needed.</div></div><div><h3>Clinical significance</h3><div>Given the current limitations of the evidence base, dental professionals should play an active role in tobacco harm reduction strategies by monitoring oral health during NCNP use and supporting product choice based on safety, tolerability, and individual patient needs.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105910"},"PeriodicalIF":4.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Gamal Mohamed Raghip , John C. Comisi , Hamdi H. Hamama , Salah Hasab Mahmoud
{"title":"Two-year randomized clinical trial to evaluate the performance of posterior bulk-fill resin composite with ionic releasing restorative material","authors":"Ahmad Gamal Mohamed Raghip , John C. Comisi , Hamdi H. Hamama , Salah Hasab Mahmoud","doi":"10.1016/j.jdent.2025.105912","DOIUrl":"10.1016/j.jdent.2025.105912","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare the two-year clinical performance of a bioactive ionic resin restorative (Activa™ BioActive-Restorative™) with that of a conventional bulk-fill composite (Filtek™ One Bulk Fill Restorative) in Class I posterior restorations.</div></div><div><h3>Methods</h3><div>A randomized, double-blind, split-mouth clinical trial was conducted involving 22 patients (aged 25–55 years) who required the restoration of bilateral posterior teeth with ICDAS score five lesions. A total of 44 restorations were placed: 22 used Activa™ BioActive-Restorative™ (BIR) and 22 used Filtek™ One Bulk Fill Restorative (BFC). Cavity preparation included selective caries removal and selective enamel etching, followed by the application of adhesive. Clinical evaluations using modified FDI criteria were conducted at 3, 6, 12, and 24 months. Statistical analyses employed Chi-square, Fisher’s exact test, and Cochran’s tests.</div></div><div><h3>Results</h3><div>Both materials demonstrated excellent performance across all clinical parameters, with no failures or secondary caries reported over a 24-month period. No statistically significant differences were observed between groups at the 3-, 6-, or 12-month follow-ups. However, significant differences were identified at 24 months in surface luster, occlusal wear, anatomical form, and material fracture (<em>p</em> < 0.05), favoring the BIR group. Intra-group analysis also revealed significant changes over time in both groups.</div></div><div><h3>Conclusions</h3><div>When combined with an adhesive protocol, BIR exhibited performance similar to a traditional bulk-fill composite over two years, showing improved long-term stability in specific parameters. Its bioactive characteristics and excellent wear resistance position it as a strong alternative for posterior restorations.</div></div><div><h3>Clinical significance</h3><div>Bioactive restorative materials may enhance the long-term performance of posterior tooth restorations when used in conjunction with appropriate bonding techniques.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105912"},"PeriodicalIF":4.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ralf-Joachim Kohal , Futoshi Komine , Agneta Lith , Benedikt C. Spies , Felix Burkhardt , Kirstin Vach
{"title":"One-piece zirconia oral implants supporting three-unit fixed dental prostheses: Ten-year results from a prospective case series","authors":"Ralf-Joachim Kohal , Futoshi Komine , Agneta Lith , Benedikt C. Spies , Felix Burkhardt , Kirstin Vach","doi":"10.1016/j.jdent.2025.105911","DOIUrl":"10.1016/j.jdent.2025.105911","url":null,"abstract":"<div><h3>Objectives</h3><div>This prospective case series aimed to evaluate the long-term clinical and radiographic outcomes of one-piece zirconia implants used to support three-unit fixed dental prostheses after a decade of functional loading. The primary endpoint was implant survival.</div></div><div><h3>Materials and methods</h3><div>A total of 54 implants were placed in 27 patients using a one-stage surgical approach with immediate provisionalization. Peri-implant bone loss was assessed using standardized radiographs; soft-tissue parameters were also evaluated. Statistical analysis was conducted using linear mixed regression models and Wilcoxon Signed Rank tests to compare differences over time and between variable groups (<em>p</em> < 0.05).</div></div><div><h3>Results</h3><div>One patient was lost to follow-up after one year, and another declined participation in the 10-year evaluation. Over the 10-year period, 21 implants failed, leading to a cumulative survival rate of 59.26 %. The mean marginal bone loss of the remaining implants was measured at 1.61 mm. Probing depth, clinical attachment loss, bleeding on probing and plaque index showed an increase from the initial prosthesis placement to the 10-year follow-up.</div></div><div><h3>Conclusions</h3><div>The studied one-piece zirconia implants demonstrated lower survival rates compared to previously reported survival rates of zirconia and titanium implants. Implant failures were mainly due to peri‑implantitis, necessitating their removal. This specific implant is not commercially available.</div></div><div><h3>Clinical significance</h3><div>Despite favorable initial outcomes, the one-piece zirconia implants studied showed a low 10-year survival rate, primarily due to peri‑implantitis. These findings highlight the importance of long-term monitoring and material selection when using zirconia implants to support multi-unit restorations. Clinicians should exercise caution with similar implant designs.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105911"},"PeriodicalIF":4.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yanlin Xia , Jiakang Zhu , Wenxiang Wang , Shanshan Liang , Cui Huang
{"title":"Colour prediction for restoring discoloured teeth using zirconia veneers","authors":"Yanlin Xia , Jiakang Zhu , Wenxiang Wang , Shanshan Liang , Cui Huang","doi":"10.1016/j.jdent.2025.105902","DOIUrl":"10.1016/j.jdent.2025.105902","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to derive predictive formulas for the final colour of restorations for discoloured teeth using zirconia veneers.</div></div><div><h3>Methods</h3><div>Coping thickness and translucency of zirconia, background colour, and luting cement shade were assessed. Shapiro-Wilk, ANOVA, paired <em>t</em>-tests, independent <em>t</em>-tests, Tukey’s test, and Automatic linear modeling (<em>p</em> < 0.05) were employed to develop a clinically practical method for predicting the colour difference (ΔE) between sample combinations (SCs) and the shade guides. ΔE values were evaluated against perceptibility (PT = 2.6) and acceptability (AT = 5.5) thresholds.</div></div><div><h3>Results</h3><div>Most discoloured teeth could be restored for A2 or A3 target shade. Using 1.5 mm CAD-CAM zirconia ceramic can achieve PT when the background colour is ND5, ND7, ND8. ΔE between the 1.5 mm LT SCs and the A2 shade guide is mostly within the AT range. ΔE between SCs and A2 shade guide showed a positive association with ND9 and negative associations with ND4, ND5, 1.5 mm, 1.0 mm, LT, and BL (<em>p</em> < 0.001). ΔE between SCs and A3 shade guide correlated positively with ND4, ND5, and ND9 but negatively with 1.5 mm, 1.0 mm, and LT (<em>p</em> < 0.001).</div></div><div><h3>Conclusions</h3><div>Each factor differentially influenced the final colour, with background colour being the most significant, followed by coping thickness. Two formulas can be used to predict ΔE between the restoration for discoloured teeth using zirconia veneers and the target shade (A2 or A3).</div></div><div><h3>Clinical significance</h3><div>The proposed formulas facilitate colour prediction in zirconia veneers for discoloured teeth, enhancing clinical aesthetic outcomes.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105902"},"PeriodicalIF":4.8,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}