Journal of Dental Sciences最新文献

{"title":"Dental students’ perceptions of two immersive reality haptic dental simulators: A pilot study","authors":"Min-Hsun Hsu, Yu-Chao Chang","doi":"10.1016/j.jds.2024.12.021","DOIUrl":"10.1016/j.jds.2024.12.021","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1353-1354"},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of Sjögren's syndrome via biopsy of the tongue but not the lip: An intriguing case report","authors":"Sak Lee","doi":"10.1016/j.jds.2024.12.022","DOIUrl":"10.1016/j.jds.2024.12.022","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1351-1352"},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in prognostic factors and genomic variations in oral squamous cell carcinoma: A 5-year retrospective study","authors":"Hui-Hsin Ko ,&nbsp;Fang-Yu Wu ,&nbsp;Ya-Syuan Chen ,&nbsp;Wender Lin ,&nbsp;Chun-Kai Fang ,&nbsp;Chyi-Huey Bai ,&nbsp;Hung-Ying Lin ,&nbsp;Hsiang-Fong Kao ,&nbsp;Shih-Jung Cheng","doi":"10.1016/j.jds.2024.12.014","DOIUrl":"10.1016/j.jds.2024.12.014","url":null,"abstract":"<div><h3>Background/purpose</h3><div>This study examined the prognostic factors and genomic variations in oral squamous cell carcinoma (OSCC) among male and female patients, focusing on the rising incidence of OSCC in women.</div></div><div><h3>Materials and methods</h3><div>Using data from 98 OSCC cases treated at National Taiwan University Hospital between 2013 and 2018, the study analyzed the patient cohort, clinical characteristics, and genomic profiles.</div></div><div><h3>Results</h3><div>The Female patients had a higher incidence of tongue cancer, while the male patients were prone to have buccal cancer. Key prognostic factors included age over 55 years, tongue cancer, alcohol use in female patients as well as the buccal cancer, betel chewing, and smoking in male patients. Notably, women with tongue OSCC or without oral habits had poorer 5-year survival rates. Genomic analysis revealed the males with high-risk habits had elevated antigen-processing and reactive oxygen gene sets, whereas the low-risk females showed dysregulation in metabolic pathways. Immunologically, the female patients had fewer naïve B cells and higher suppressive M2 macrophages.</div></div><div><h3>Conclusion</h3><div>Our findings highlight distinct sex-related OSCC prognosis differences and suggest that personalized treatments targeting specific risk factors and genomic characteristics may improve the clinical outcomes, particularly for the female OSCC patients.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1086-1094"},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for inferior alveolar nerve injury associated with implant surgery: An observational study","authors":"Jisuk Han ,&nbsp;Jeong Joon Han","doi":"10.1016/j.jds.2024.07.025","DOIUrl":"10.1016/j.jds.2024.07.025","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Inferior alveolar nerve (IAN) injury is the most serious complication associated with dental implant surgery, posing difficulties in treatment and potential for permanent disabilities. This study aimed to identify patient-related risk factors for IAN injury during implant placement and to investigate sensory disturbances depending on whether the implant was removed.</div></div><div><h3>Materials and methods</h3><div>Twenty-eight patients with implant-related IAN injury were included. To determine risk factors, patient demographics and radiographic images were analyzed. Sensory functions were evaluated and compared based on whether the implant was removed.</div></div><div><h3>Results</h3><div>IAN injury occurred more frequently in women (60.7%), with a mean age of 62.9 years. The distance from the alveolar crest to the IAN was 9.8 ± 3.0 mm, with 40.9% patients having a residual alveolar bone of 10 mm or more. The mean bone density was measured at 586.2 ± 392.5 HU, which is below the normal range for the mandible. Notably, 31.8% of the patients were found to have D4 bone. Compared to patients who did not have implants removed, those who did showed better sensory function, except pressure perception, although these differences were not statistically significant.</div></div><div><h3>Conclusion</h3><div>Older women with lower bone density were at an increased risk of IAN injury, and IAN injury occurred even in cases with sufficient alveolar ridge. The removal of implants related to the injury alone does not markedly influence the extent of sensory disturbances during follow-up period, suggesting that other aspects such as the timing of removal and severity of injury could be crucial.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 270-277"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scientometric study on research trends and characteristics of discoid lupus erythematosus","authors":"Yun Wang ,&nbsp;Yuhan Zhu ,&nbsp;Chenping Zhang ,&nbsp;Wei Liu","doi":"10.1016/j.jds.2024.10.003","DOIUrl":"10.1016/j.jds.2024.10.003","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Discoid lupus erythematosus (DLE) serves as an interdisciplinary disease involved in dermatology and stomatology in many cases. The purpose of this study was to analyze the scientometric characteristics and research trends of DLE.</div></div><div><h3>Materials and methods</h3><div>All the papers on DLE were comprehensively retrieved from the Scopus database. Discipline comparison (dermatology versus others) and chronological comparison (before 2005 versus 2005–2024) were performed, so that the number of papers can be to some extent compared in the analysis.</div></div><div><h3>Results</h3><div>Among all the 1239 papers on DLE, 738 (59.6 %) were published by dermatologists. Diagnosis aspect, skin manifestation, facial dermatoses, scar formation, hair loss, epiluminescence microscopy, dermoepidermal junction, arthralgia, anamnesis, young adult, Ro antibody, and dermoscopy were distinctive keywords for dermatologists; While Mouth mucosa, mouth diseases, lip neoplasms, eyelid disease, blepharitis, conjunctivitis, autoantibody, blood, neutrophil, fever, sex difference, preschool child were distinctive keywords for other scholars. Treatment response, dapsone, etretin, clobetasol, mycophenolate mofetil, glucocorticoid, triamcinolone, and drug safety were therapeutic keywords for dermatologists. Whereas quinacrine, alpha tocopherol, hydrocortisone, adverse drug reaction were therapeutic keywords for other scholars. The trend has changed to complication, disease duration, young adult, dermatitis, pruritus, antibody titer, Ro antibody, anamnesis, dermoscopy, arthralgia, dermoepidermal junction, keratosis, and African American, drug withdrawal, tacrolimus, mycophenolate mofetil, etretin, clobetasol, cyclophosphamide, and drug safety after 2005.</div></div><div><h3>Conclusion</h3><div>This scientometric study elucidated the current scenario and research trends of DLE, and would help in improving in reciprocal collaboration and communication for investigations on this disease.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 667-671"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparisons of precision and trueness of digital dental casts produced by desktop scanners and intraoral scanners","authors":"Chun-Chao Chuang ,&nbsp;Feng-Chou Cheng ,&nbsp;Mu-Hsiung Chen ,&nbsp;Wei-Chun Lin ,&nbsp;Chun-Pin Chiang","doi":"10.1016/j.jds.2024.09.016","DOIUrl":"10.1016/j.jds.2024.09.016","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Different types of scanners are gradually used to produce digital dental casts in the current dental practice. This study tested the accuracy of the three desktop scanners and two intraoral scanners and evaluated whether the desktop scanners had higher precision than the intraoral scanners.</div></div><div><h3>Materials and methods</h3><div>This study used the three desktop and two intraoral scanners to scan a standard dental cast 5 times. The 5 digital casts produced by the same scanner were compared each other to study the precision errors of each scanner. Moreover, 5 sets of the 5 digital casts produced by the 5 different scanners were compared each other to investigate the trueness errors among these 5 different scanners.</div></div><div><h3>Results</h3><div>This study showed a significant difference in the precision error of produced digital casts made by the 5 different scanners (<em>P</em> &lt; 0.0001). The two intraoral scanners had significantly higher precision errors of produced digital casts than the three desktop scanners. However, there were no significant differences in the precision errors among the three desktop scanners and between the two intraoral scanners. The results of the whole cast or particular tooth surface trueness analyses demonstrated that the trueness errors were concentrated at the molar regions of produced digital casts when comparisons were performed between the intraoral and desktop scanners.</div></div><div><h3>Conclusion</h3><div>We conclude that the desktop scanners can achieve a better precision than the intraoral scanners. When the intraoral scanner is used, the dentist should notice the possible model errors at the molar regions.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 137-146"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgery of impacted maxillary second premolar beneath first molar trifurcation via lateral window maxillary sinus augmentation: A case report","authors":"Chen-Chieh Hsu,&nbsp;Meng-Ling Chiang,&nbsp;Jyh-Kwei Chen","doi":"10.1016/j.jds.2024.09.020","DOIUrl":"10.1016/j.jds.2024.09.020","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 704-706"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Titanium particle-induced inflammasome in human gingival epithelial cells","authors":"Shin Wakuda ,&nbsp;Akira Hasuike ,&nbsp;Kyoko Fujiwara ,&nbsp;Ryo Sakai ,&nbsp;Akhilanand Chaurasia ,&nbsp;Toshio Uchiyama ,&nbsp;Shuichi Sato","doi":"10.1016/j.jds.2024.06.013","DOIUrl":"10.1016/j.jds.2024.06.013","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Peri-implantitis remains a substantial challenge. This study investigated the effect of titanium particles on human oral epithelial cells, focusing on the nucleotide-binding domain and leucine-rich repeat protein (NLRP) 3 inflammasome.</div></div><div><h3>Materials and methods</h3><div>The Ca9-22 human gingival epithelial cell line was subjected to incubation with titanium particles. To evaluate cell viability, the MTT assay was employed. Total RNA was extracted, and messenger RNA (mRNA) expressions of <em>COX2</em>, <em>TGF-β1</em>, <em>NLRP1</em>, <em>NLPR3</em>, <em>CASP1</em>, and <em>AIM2</em> were analyzed. The concentration of interleukin (IL)1β in cell supernatants was quantified through enzyme-linked immunosorbent assay. Intracellular reactive oxygen species (ROS) were visualized using an ROS assay Kit.</div></div><div><h3>Results</h3><div>Ca9-22 cells treated with titanium particles showed &gt;75% cell viability across all concentrations tested, with consistent results. mRNA expressions of inflammation-related genes (<em>COX2</em> and <em>TGF-β1</em>) significantly increased in a dose-dependent manner. The mRNA expression of <em>NLRP3</em> and <em>CASP1</em>, as well as the secretion of IL1β, increased after 6-h incubation with titanium particles. Moreover, the ROS assay results showed increased production of ROS after treatment with titanium particles, whereas NLRP3 expression and IL1β secretion reduced after treatment with N-acetyl-<span>l</span>-cysteine (ROS scavenger).</div></div><div><h3>Conclusion</h3><div>Our findings indicate that titanium particles possess a distinct ability to trigger the NLRP3 inflammasome, partly by producing ROS.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 384-392"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between oral health literacy and changes in self-assessment of oral health during COVID-19","authors":"Yuko Hirota ,&nbsp;Naoko Adachi ,&nbsp;Kanade Ito ,&nbsp;Kayoko Shinada ,&nbsp;Yuji Kabasawa","doi":"10.1016/j.jds.2024.04.015","DOIUrl":"10.1016/j.jds.2024.04.015","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Health literacy is thought to play a major role in implementing health behaviors, such as preventing coronavirus disease 2019 (COVID-19). In this study, we aimed to examine the relationship between oral health literacy (OHL), dietary literacy (DL), and changes in oral health and eating habits during the COVID-19 pandemic.</div></div><div><h3>Materials and methods</h3><div>The self-assessment questionnaire, including questions on oral and dietary conditions for each period of the COVID-19 pandemic, sources of information, OHL, DL, and frequency of COVID-19 prevention measures, was administered using a web research company. All participants were divided into low- and high-literacy groups based on the median scores: those who scored above the median in the high group and those who scored at or below the median in the low group. Comparisons were conducted between the two groups.</div></div><div><h3>Results</h3><div>The median OHL and DL scores were 16 and 17 for the 344 participants included in the study (168 males and 176 females); 160 (46.5%) participants had high OHL scores, and 157 (45.6%) had high DL scores. The group with high OHL or DL tended to collect information sent by medical professionals compared to the group with low OHL or DL, had significantly higher scores on self-assessment of oral and dietary conditions, and tended to implement infection control actions more frequently in eating situations.</div></div><div><h3>Conclusion</h3><div>The high OHL and DL groups gathered information from professionals to have attain oral and dietary conditions regardless of COVID-19 and tended to implement infection prevention measures in oral health and diet.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 569-577"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemokine receptor-2 deficiency induced mild experimental periapical lesion in mice","authors":"Qiao Ling ,&nbsp;Ai-jing Wang ,&nbsp;Xiao-yan Wang","doi":"10.1016/j.jds.2024.06.005","DOIUrl":"10.1016/j.jds.2024.06.005","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Macrophages are considered to play an important role in the development of chronic apical periodontitis (CAP). However the function of tissue resident macrophages in CAP is unclear. This study aims to investigate the potential role of macrophages of different origins in CAP.</div></div><div><h3>Materials and methods</h3><div>Chemokine receptor-2 deficiency (CCR2^−/−) mice and C57BL/6N mice (control group, WT mice) were used to induce apical periodontitis. The pulp of mandibular first molars of both sides were exposed to the oral environment. After 0, 7, 21, 28 days of pulp explosion, animals were sacrificed, the mandibular bones were collected and scanned with micro-CT, further processed for HE &amp; IHC Staining to analyze the development of CAP, as well as the expression of surface markers of macrophages.</div></div><div><h3>Results</h3><div>Both CCR2^−/− and WT mice exhibited CCR2 negative macrophages in normal periapical area, which indicated the presence of tissue resident macrophages. CCR2 deficiency decreased the number of macrophages in periapical lesions, the M1 type macrophages’ number as well as osteoclasts around the edge of the lesion decreased compared to wild type. Meanwhile CCR2 deficiency decreased the volume of periapical lesion significantly compared to wild type, but did not inhibite and disappeare the lesion thoroughly.</div></div><div><h3>Conclusion</h3><div>Monocyte-macrophage system derived macrophages promote the progression of periapical lesions, while tissue resident macrophages in periodontal ligament might also be involved in the progression of periapical lesion.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 402-409"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141400057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}