Journal of Dental Sciences最新文献

{"title":"Complicated management of a surgical site infection following open reduction and internal fixation of a mandibular condylar fracture in a patient with multiple antibiotic allergies","authors":"Keigo Maeda, Shinsuke Yamamoto, Naoki Taniike","doi":"10.1016/j.jds.2025.09.004","DOIUrl":"10.1016/j.jds.2025.09.004","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 655-656"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145903814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabricated citations in the age of AI: A wake-up call for editors, reviewers, and authors","authors":"He Liu","doi":"10.1016/j.jds.2025.10.024","DOIUrl":"10.1016/j.jds.2025.10.024","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 679-680"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145903895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between dental amalgam fillings and urinary mercury levels in the Jordanian population: A comparative population-based study","authors":"Ibrahim Al-Odat ,&nbsp;Saad Al-Fawaeir ,&nbsp;Naser Odat","doi":"10.1016/j.jds.2025.05.022","DOIUrl":"10.1016/j.jds.2025.05.022","url":null,"abstract":"<div><h3>Background/purpose</h3><div>The health risks of mercury-containing dental amalgam fillings remain controversial. Urinary mercury levels are used as a tool to assess mercury exposure toxicity. Therefore, this study aimed to examine the effects of dental amalgam fillings on urinary mercury levels in the Jordanian population.</div></div><div><h3>Materials and methods</h3><div>This study recruited an experimental group of 108 participants with dental amalgam fillings and control group of 109 participants without dental amalgam fillings. Urinary mercury levels were measured and compared between the two groups.</div></div><div><h3>Results</h3><div>The results showed a statistically significant increase in urinary mercury concentration in participants with dental amalgam fillings compared to participants with no dental amalgam fillings (6.42 ± 0.37 μg/L vs 1.55 ± 0.05 μg/L, <em>P</em> &lt; 0.05). It also showed that this increase in urinary mercury levels among Jordanians with dental amalgam fillings was statistically significant when individuals had more than 6 dental amalgam fillings (9.36 ± 1.68 μg/L) compared to those with fewer than 6 (4.73 ± 0.34 μg/L, <em>P</em> &lt; 0.05). Increased urinary mercury levels among Jordanians were also correlated with having dental amalgam fillings for more than 10 years.</div></div><div><h3>Conclusion</h3><div>Increased urinary mercury levels in the Jordanian population are correlated with both the number of amalgam fillings and the duration of having these fillings. However, this increase in urinary mercury levels observed in this study is below the threshold that would pose significant health risks.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 225-231"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145903948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scientometric and comparative study of rhabdomyosarcoma research by pediatricians and stomatologists","authors":"Wenke Chen ,&nbsp;Hui Li ,&nbsp;Zhenhu Ren ,&nbsp;Chongfang Zhang","doi":"10.1016/j.jds.2025.09.019","DOIUrl":"10.1016/j.jds.2025.09.019","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Rhabdomyosarcoma (RMS) frequently affects pediatric patients and common occurs in the head and neck region. The purpose of this study was to compare the scientometric characteristics of RMS publications by pediatricians and stomatologists.</div></div><div><h3>Materials and methods</h3><div>All the papers on RMS were comprehensively retrieved from the Scopus database, and divided into pediatricians and stomatologists groups.</div></div><div><h3>Results</h3><div>There were 2211 and 234 papers on RMS were published by rheumatologists and stomatologists, respectively. The total citation count was 63,868 and the <em>h</em> index was 111 for RMS publications by pediatricians, while the respective values for stomatologists were 2952 and 29. The two major subtypes of RMS are embryonal and alveolar types, and genetic alterations further categorize RMS into <em>PAX3/7–FOXO1</em> fusion-positive and fusion-negative types. Cancer chemotherapy mainly vincristine, dactinomycin, and cyclophosphamide, surgery, radiotherapy, and brachytherapy were the common keywords of treatment. The more common keywords such as age, facial neoplasms, mouth neoplasms, orbital neoplasms, gingiva, mandible, DNA-binding proteins, gene silencing, and Rh30 cell line were reported by stomatologists.</div></div><div><h3>Conclusion</h3><div>This study is the first comprehensive report of the scientometric characteristics of RMS publications by pediatricians and stomatologists, highlighting the need for increased awareness among clinicians to avoid diagnostic delays and ensure timely treatment.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 610-614"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of restorative materials, colors, and surface finishing on the scanning accuracy of an intraoral scanner","authors":"Sophia Lin ,&nbsp;Wei-Chun Lin ,&nbsp;Amal Alfaraj","doi":"10.1016/j.jds.2025.10.040","DOIUrl":"10.1016/j.jds.2025.10.040","url":null,"abstract":"<div><h3>Background/purpose</h3><div>When teeth are restored using dental materials, there is potential for these restorations to influence the accuracy of intraoral scans. Such variations in accuracy could subsequently affect the precision of the derived virtual cast, the registration of the maxillo-mandibular relationship, and the fabrication of prostheses. This study aimed to assess the effect of various restorative materials, prosthesis colors, and their surface finishes on the accuracy of intraoral scans performed with a TRIOS 4 scanner.</div></div><div><h3>Materials and methods</h3><div>Using a 4 × 2 × 2 factorial experimental design, the research analyzed how metal-ceramic, zirconia, lithium disilicate, and milled PMMA; shades B1 and A4; and surface finishes (either polishing or glazing) influence the trueness and precision of scans. The trueness and precision were quantified using root mean square (RMS) values.</div></div><div><h3>Results</h3><div>Significant differences in scan accuracy were observed, contingent on material, color, and finishing, along with notable interactions between these factors. Overall, PMMA exhibited the highest trueness and zirconia demonstrated the best precision. Polished lithium disilicate and PMMA showed better trueness for the A4 shade, whereas glazed lithium disilicate and PMMA performed better for the B1 shade. Metal-ceramic restorations showed an opposite trend. Zirconia restorations showed better trueness for A4 shade than B1 shade for both polished and glazed surfaces.</div></div><div><h3>Conclusion</h3><div>Significant interactions between materials, colors, and surface treatments were observed. Although clinicians may not be able to modify existing restorations' materials, color, or surface treatment, they need to be mindful that the intricate interaction of these factors will affect the accuracy of intraoral scans.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 533-540"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zygomatic fracture characteristics and their association with brain injury: Evidences from a 10-year retrospective study in northern Taiwan","authors":"Wei-Che Tsai ,&nbsp;Chen-Yin Yong ,&nbsp;Sam Li-Sheng Chen ,&nbsp;Yoichi Ohiro ,&nbsp;Chih-Yuan Fang","doi":"10.1016/j.jds.2025.08.002","DOIUrl":"10.1016/j.jds.2025.08.002","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Few studies have systematically examined the relationship between zygomatic fracture patterns or patient demographics and head injury. This study investigates the epidemiology of zygomatic fractures, their association with brain injury, and the influence of patient age, focusing on fracture classification and injury mechanisms.</div></div><div><h3>Materials and methods</h3><div>A retrospective analysis of 272 patients with zygomatic fractures treated between 2012 and 2021 at a medical center in northern Taiwan was conducted. Fractures were classified using the Zingg system. Clinical data including age, injury etiology, concomitant injuries, and brain injury were analyzed. Statistical methods included chi-square tests, one-way ANOVA, and multiple logistic regression.</div></div><div><h3>Results</h3><div>Motorcycle accidents were the most common cause of zygomatic fractures (43.4 %), followed by falls (27.9 %). The highest incidence occurred in patients aged 61–70 years. Older patients had significantly lower surgical intervention rates (<em>P</em> &lt; 0.05). Type B fractures were most common (51.8 %), and bilateral fractures were significantly associated with higher rates of brain injury (58.3 % vs. 26.6 %, <em>P</em> &lt; 0.05). Among patients with fall-related fractures, those with brain injury were significantly older than those without (<em>P</em> = 0.008). Even low-energy trauma, such as ground-level falls, led to brain injury in elderly patients. In younger individuals, brain injury was associated with bilateral fractures and concomitant injuries, whereas in older patients, age itself was a major risk factor for brain injury.</div></div><div><h3>Conclusion</h3><div>Falls are increasingly associated with zygomatic fractures in older adults, and even minor trauma can result in brain injury. Bilateral fractures and high-energy mechanisms remain key predictors of brain injury in younger patients.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 250-257"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suppression of distal-less homeobox 3 increased alveolar bone mass in mouse tooth socket by targeting thrombospondin 1","authors":"Chang Diao ,&nbsp;Fang Li ,&nbsp;Kai Sun ,&nbsp;Miao Yu ,&nbsp;Haochen Liu ,&nbsp;Hailan Feng ,&nbsp;Yang Liu ,&nbsp;Dong Han","doi":"10.1016/j.jds.2025.07.008","DOIUrl":"10.1016/j.jds.2025.07.008","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Alveolar ridge resorption after tooth extraction significantly impacts dental implantation and prosthodontic treatment outcomes. Sustaining alveolar bone mass remains a critical clinical challenge and a major focus of research. Notably, patients with tricho-dento-osseous (TDO) syndrome, characterized by distal-less homeobox 3(<em>DLX3</em>) loss-of function mutations, exhibit increased jaw bone density and demonstrate long-term preservation of alveolar bone mass post-tooth extraction. This study aimed to investigate the effects of <em>DLX3</em> knockdown on bone remodeling following tooth extraction and to elucidate the underlying molecular mechanisms.</div></div><div><h3>Materials and methods</h3><div>we established a murine maxillary incisor extraction model to investigate alveolar bone healing. An empty adenoviral vector or an adenoviral vector designed to suppress <em>Dlx3</em> gene expression was delivered into the alveolar sockets of wild-type C57BL/6 mice, respectively. Histological staining, micro-computed tomography (micro-CT), immunohistochemistry, immunofluorescence, and RNA sequencing were employed to evaluate the outcomes.</div></div><div><h3>Results</h3><div>Histological analysis revealed accelerated bone formation and increased alveolar bone mass in the <em>Dlx3</em>-knockdown group. This phenotype was attributed to the activation of osteoblasts, which promoted new bone formation, and the inhibition of osteoclasts, which reduced bone resorption, without compromising normal bone structure of newly formed bone. RNA sequencing identified thrombospondin 1(<em>Thbs1</em>) as a key downstream gene. Downregulation of <em>Thbs1</em> following <em>Dlx3</em>-knockdown enhanced angiogenesis and osteogenesis. Conversely, the addition of recombinant THBS1 protein after <em>Dlx3</em> inhibition partially reversed the enhanced osteogenic phenotype.</div></div><div><h3>Conclusion</h3><div>Suppression of <em>Dlx3</em> increased alveolar bone mass by down-regulation of <em>Thbs1</em>. Our study provides a theoretical foundation for developing novel strategies to preserve alveolar bone.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 115-124"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel MMP20 (matrix metalloproteinase 20) mutations causing hypoplastic-hypomaturation amelogenesis imperfecta","authors":"Shih-Kai Wang ,&nbsp;Hong Zhang ,&nbsp;Hua-Chieh Lin ,&nbsp;Yin-Lin Wang ,&nbsp;J. Timothy Wright ,&nbsp;John D. Bartlett ,&nbsp;James P. Simmer ,&nbsp;Jan C.-C. Hu","doi":"10.1016/j.jds.2025.08.039","DOIUrl":"10.1016/j.jds.2025.08.039","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Matrix metalloproteinase 20 (MMP20) is a proteinase essential for dental enamel formation. Mutations in human <em>MMP20</em> cause autosomal recessive amelogenesis imperfecta (AI), characterized by thin and soft enamel. This study aimed to unravel the genetic causes for five families with hypoplastic-hypomaturation AI.</div></div><div><h3>Materials and methods</h3><div>Whole-exome analyses and Sanger sequencing were performed to identify and confirm disease-causing mutations. To evaluate the pathogenicity of identified <em>MMP20</em> missense variants, immunoblotting and gelatin zymography were conducted on proteins overexpressed in HEK293T cells.</div></div><div><h3>Results</h3><div>All affected individuals from the five families exhibited similar dental phenotypes, including chalky-white to yellow-brown discolorations and evident dental attrition. The defective enamel was both thin and hypomineralized. Six pathogenic <em>MMP20</em> variants were identified: c.289A&gt;T (p.Lys97∗), c.547G&gt;A (p.Asp183Asn), c.686G&gt;A (p.Gly229Asp), c.102G&gt;A (p.Trp34∗), c.359dup (p.Asn120Lysfs∗9), and c.954-2A&gt;T. Among them, the first three have not been previously reported. The two missense mutations altered evolutionarily conserved amino acid residues within the catalytic domain of MMP20. Compared with the wild type, secretion of both mutant MMP20 proteins was significantly impeded, and neither displayed proteolytic activity on gelatin zymography, indicating a loss of enzymatic function.</div></div><div><h3>Conclusion</h3><div>This study expands the genotypic spectrum of <em>MMP20</em>-associated AI and highlights two critical residues within the MMP20 catalytic domain that are essential for its secretion and enzymatic activity.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 305-314"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical evaluation of bone regeneration induced by human umbilical cord mesenchymal stem cells around implants in an osteoporotic rat model","authors":"Mefina Kuntjoro ,&nbsp;Nike Hendrijantini ,&nbsp;Michael Josef Kridanto Kamadjaja ,&nbsp;Bambang Agustono Satmoko Tumali ,&nbsp;Jennifer Widjaja ,&nbsp;Eric Priyo Prasetyo ,&nbsp;Guang Hong","doi":"10.1016/j.jds.2025.08.042","DOIUrl":"10.1016/j.jds.2025.08.042","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Osteoporosis in the jawbone can compromise the success of dental implant treatment. Human umbilical cord mesenchymal stem cells (hUCMSCs) have demonstrated osteogenic differentiation potential. This study aimed to evaluate the effect of hUCMSC induction on implant osseointegration in an osteoporotic animal model.</div></div><div><h3>Materials and methods</h3><div>Twenty-eight osteoporotic female Wistar rats were divided into control and hUCMSC-induced groups and observed at 2 and 4 weeks. The treatment group received hUCMSC injections into the implant area of the femur osteoporotic model. Specimens were stained using immunohistochemical and haematoxylin and eosin techniques to assess osteogenic marker expression. Data were analysed using Kruskal–Wallis and Mann–Whitney U test.</div></div><div><h3>Results</h3><div>Bone-implant volume (BIV) was significantly greater in the hUCMSC-induced groups compared to controls. The expression of osterix, RUNX family transcription factor 2 (RUNX2), tumor necrosis factor (TNF)-α, nuclear factor of activated T cells 1 (NFATc1), collagen type 1, and osteocalcin decreased in osteoblasts from week 2 to week 4. Significant differences (<em>P</em> &lt; 0.05) were observed between control and hUCMSC groups at both time points. These findings suggest that bone formation was completed by week 4, entering the bone maturation phase, supported by the increased BIV in the hUCMSC group.</div></div><div><h3>Conclusion</h3><div>Induction with hUCMSCs promotes both early and late osseointegration in osteoporotic animal models. These results highlight the efficacy of hUCMSCs in enhancing bone healing after implant placement under osteoporotic conditions.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 294-304"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor microenvironment-derived IL-32 promotes aggressive phenotypes and stem cell traits in head and neck squamous cell carcinoma","authors":"Nien-Tzu Liu ,&nbsp;Shin-Hsien Yang ,&nbsp;Yi-Ming Chang ,&nbsp;Jian-Hong Yu ,&nbsp;Su-Feng Chen ,&nbsp;Yaoh-Shiang Lin ,&nbsp;Yu-Chun Lin","doi":"10.1016/j.jds.2025.10.010","DOIUrl":"10.1016/j.jds.2025.10.010","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy distinguished by marked invasiveness, a high metastatic propensity, and poor prognosis. Cancer-associated fibroblasts (CAFs) within the tumour microenvironment secrete numerous mediators that accelerate tumour progression; however, the precise contribution of CAF-derived interleukin-32 (IL-32) remains unclear. This study examined the influence of CAF-derived IL-32 on invasion, epithelial–mesenchymal transition (EMT), and cancer-stem-cell (CSC) traits in HNSCC.</div></div><div><h3>Materials and methods</h3><div>Primary CAFs and normal fibroblasts (NFs) were isolated from HNSCC specimens. IL-32 expression was quantified by microarray analysis, quantitative PCR, Western blotting, and enzyme-linked immunosorbent assay. Migration and invasion of FaDu and SCC25 cells were assessed with Transwell assays after exposure to CAF-conditioned medium or recombinant IL-32. EMT markers were evaluated by Western blotting, whereas sphere-formation assays and flow cytometry for CD133⁺/CD44⁺/CD24⁺ populations were used to determine stemness.</div></div><div><h3>Results</h3><div>IL-32 was significantly up-regulated in CAFs compared with NFs. Both CAF-conditioned medium and recombinant IL-32 markedly increased the migratory and invasive capacities of HNSCC cells. These treatments reduced E-cadherin and increased Vimentin, Snail, and Twist expression, while enhancing sphere formation and expanding CD24⁺, CD44⁺ and CD133⁺ sub-populations.</div></div><div><h3>Conclusion</h3><div>CAFs promote HNSCC progression through IL-32-mediated enhancement of invasion, EMT induction, and CSC properties. Targeting IL-32 signalling may represent a promising therapeutic approach to improve outcomes in HNSCC.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"21 1","pages":"Pages 475-483"},"PeriodicalIF":3.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}