{"title":"Perspectives of the new horizon in bone regeneration with standardized, centrally manufactured freeze-dried platelet-rich plasma","authors":"Yi-Tzu Chen , Pei-Yin Chen , Yu-Chao Chang","doi":"10.1016/j.jds.2025.08.008","DOIUrl":"10.1016/j.jds.2025.08.008","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 4","pages":"Pages 2489-2491"},"PeriodicalIF":3.1,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145021069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Yu-Fong Chang , Yu-Hsueh Wu , Yi-Pang Lee , Yi-Ping Wang , Andy Sun , Chun-Pin Chiang
{"title":"Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with normocytosis","authors":"Julia Yu-Fong Chang , Yu-Hsueh Wu , Yi-Pang Lee , Yi-Ping Wang , Andy Sun , Chun-Pin Chiang","doi":"10.1016/j.jds.2025.08.003","DOIUrl":"10.1016/j.jds.2025.08.003","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Normocytosis is defined as having the mean corpuscular volume (MCV) between 80 fL and 99.9 fL. This study evaluated whether the 474 oral lichen planus (OLP) patients with normocytosis (so-called normocytosis/OLP patients) had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than 588 healthy control subjects or 588 OLP patients.</div></div><div><h3>Materials and methods</h3><div>Complete blood count, serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 588 OLP patients, 474 normocytosis/OLP patients, and 588 healthy control subjects were measured and compared.</div></div><div><h3>Results</h3><div>We found that 14.3 %, 12.7 %, 4.0 %, 1.5 %, 16.0 %, and 19.8 % of the 474 normocytosis/OLP patients had blood hemoglobin (Hb) and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity, respectively. Furthermore, the 474 normocytosis/OLP patients had significantly higher frequencies of blood Hb and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity than 588 healthy control subjects (all <em>P</em>-values <0.05). On the contrary, the 474 normocytosis/OLP patients had significantly lower frequencies of blood Hb and serum vitamin B12 deficiencies and hyperhomocysteinemia than the overall 588 OLP patients (all <em>P</em>-values <0.05).</div></div><div><h3>Conclusion</h3><div>We conclude that there are significantly higher frequencies of anemia, serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity in normocytosis/OLP patients than in healthy control subjects. On the contrary, normocytosis/OLP patients do have significantly lower frequencies of blood Hb and vitamin B12 deficiencies and hyperhomocysteinemia than overall OLP patients.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 4","pages":"Pages 2076-2083"},"PeriodicalIF":3.1,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical removal of an asymptomatic radicular cyst after 10 years of follow-up","authors":"Feng-Chou Cheng, Ching-En Meng, Pei-Yu Hsu, Chun-Pin Chiang","doi":"10.1016/j.jds.2025.08.005","DOIUrl":"10.1016/j.jds.2025.08.005","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 4","pages":"Pages 2503-2505"},"PeriodicalIF":3.1,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145021074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Postoperative carotid sinus syndrome presenting as sinus pause in an oral cancer patient: A rare but clinically significant case","authors":"Tzu-Hao Hsiao, Tung-Nien Hsu, Po Chih Hsu","doi":"10.1016/j.jds.2025.07.025","DOIUrl":"10.1016/j.jds.2025.07.025","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 4","pages":"Pages 2506-2507"},"PeriodicalIF":3.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application model of reading the medical images from the National Health Insurance (NHI) MediCloud System for clinic dentists: A case report","authors":"Feng-Chou Cheng, Chia-Hua Shih, Yu-Jie Shen, Chun-Pin Chiang","doi":"10.1016/j.jds.2025.08.004","DOIUrl":"10.1016/j.jds.2025.08.004","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 4","pages":"Pages 2508-2510"},"PeriodicalIF":3.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current challenges of the implementation of radiology diagnosis equipment operating license for the dentists in Taiwan","authors":"Feng-Chou Cheng, Yan-De Liou, Bo-Lin Liu, Chun-Pin Chiang","doi":"10.1016/j.jds.2025.08.006","DOIUrl":"10.1016/j.jds.2025.08.006","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 4","pages":"Pages 2511-2512"},"PeriodicalIF":3.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145021059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simultaneous presentation of three types of osteoid osteoma in the maxilla","authors":"Jen-Ho Wen , Chen-Yu Heieh , Yang-Che Wu, Chih-Yuan Fang","doi":"10.1016/j.jds.2025.07.032","DOIUrl":"10.1016/j.jds.2025.07.032","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 4","pages":"Pages 2515-2517"},"PeriodicalIF":3.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145021061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu Ting Li , Ju-Hsuan Yang , Yu-Hsin Chang , Hao-Hueng Chang , Chun-Pin Lin
{"title":"In vitro evaluation of novel composite bioceramic filaments for alveolar bone regeneration","authors":"Yu Ting Li , Ju-Hsuan Yang , Yu-Hsin Chang , Hao-Hueng Chang , Chun-Pin Lin","doi":"10.1016/j.jds.2025.07.012","DOIUrl":"10.1016/j.jds.2025.07.012","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Alveolar bone defect repair remains a major clinical challenge in oral and maxillofacial reconstruction. This study developed 3D-printable composite filaments combining polylactic acid (PLA) with bioceramic powders and evaluated their physicochemical properties and in vitro osteogenic potential for alveolar bone graft applications.</div></div><div><h3>Materials and methods</h3><div>Filaments were fabricated via hot processing and tetrahydrofuran (THF) solvent casting, blending PLA with hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) at a 7:3 ratio. Four groups, H-PLA (heated PLA), H-MIX (heated PLA with HA/β-TCP), T-PLA (THF-processed PLA), and T-MIX (THF-processed PLA with HA/β-TCP) groups, underwent material characterization such as Fourier transform infrared spectroscopy (FTIR), X-ray diffractometer (XRD), scanning electron microscopy (SEM), and compressive strength testing, and MC3T3 cell-based assays for biocompatibility assessment.</div></div><div><h3>Results</h3><div>H-MIX and T-MIX significantly enhanced compressive strength and osteogenic mineralization compared to PLA-only groups. HA/β-TCP was uniformly dispersed within the PLA matrix. Cell proliferation peaked on day 3, with both composite groups showing higher viability than controls (<em>P</em> < 0.01). Alkaline phosphatase (ALP) activity increased by day 7, with T-MIX significantly higher than H-PLA and T-PLA (<em>P</em> < 0.05). On day 14, T-MIX and H-MIX showed markedly greater mineralization, with T-MIX displaying the highest calcium deposition (<em>P</em> < 0.05 to <em>P</em> < 0.001).</div></div><div><h3>Conclusion</h3><div>Composite scaffolds made by thermal and solvent casting showed enhanced mechanical strength and osteogenic activity in vitro. T-MIX outperformed other groups in compressive strength, ALP activity, and calcium deposition. These results indicate that HA/β-TCP-reinforced PLA filaments, especially T-MIX, are promising for alveolar bone repair.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 4","pages":"Pages 2084-2091"},"PeriodicalIF":3.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}