Journal of Dental Sciences最新文献

{"title":"The relevance of dental management prior to radiation therapy with severe oral mucositis in head and neck cancer patients","authors":"Yutian Wang ,&nbsp;Zhou Huang ,&nbsp;Shaowen Xiao ,&nbsp;Baomin Zheng ,&nbsp;Dan Zhao ,&nbsp;Weixin Liu ,&nbsp;Xiaolong Xu ,&nbsp;Nan Wang ,&nbsp;Chao Yang ,&nbsp;Yanqun Zhang ,&nbsp;Yan Sun ,&nbsp;Hongwei Liu","doi":"10.1016/j.jds.2024.04.030","DOIUrl":"10.1016/j.jds.2024.04.030","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Dental management prior to radiotherapy is often time-critical, and there are no studies on whether manipulations such as tooth extraction influence the risk of severe radiation-induced oral mucositis (ROM) during radiotherapy. Therefore, the aim of this study was to describe the relationship between dental management and the incidence of severe ROM.</div></div><div><h3>Materials and methods</h3><div>A retrospective analysis was conducted on 144 head and neck cancer (HNC) patients who received dental management before radiotherapy at Peking University Cancer Hospital, from January 2016 to December 2017. Demographic characteristics, primary tumor features, cancer treatment characteristics, and severity of oral mucositis during radiotherapy were recorded. Univariate analysis and logistic regression analysis were used to explore factors associated with severe radiation-induced oral mucositis.</div></div><div><h3>Results</h3><div>The incidence of grade 3 mucositis was 14.5% (22/144); univariate analysis showed that the number of extracted teeth (OR = 1.313; 95%CI = 1.012–1.702; <em>P</em> = 0.040) and patients with primary oral cancer had a higher risk of developing grade 3 mucositis (OR = 3.848; 95% CI = 1.508–9.822; <em>P</em> = 0.005). No statistical correlation was found between pre-radiation therapy prophylaxis, dental restoration, endodontic treatment, and grade 3 mucositis (<em>P</em> &gt; 0.05). Logistic regression analysis showed that the number of extracted teeth (OR = 1.421, 95%CI = 1.071–1.885, <em>P</em> = 0.015) and primary tumor location in the oral cavity (compared with other head and neck cancers) (OR = 5.165, 95%CI = 1.636–16.311, <em>P</em> = 0.005) were significantly associated with grade 3 mucositis.</div></div><div><h3>Conclusion</h3><div>In HNC patients undergoing radiotherapy, the primary site located in the oral cavity and a higher number of teeth extracted are independent risk factors for the development of severe mucositis.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 522-528"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141057361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of a recurrent odontogenic keratocyst in the zygoma using piezoelectric instruments","authors":"I. Chen,&nbsp;Kwei-Jing Chen,&nbsp;Michael Yuan-Chien Chen","doi":"10.1016/j.jds.2024.11.004","DOIUrl":"10.1016/j.jds.2024.11.004","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 721-722"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preserving pulp vitality for teeth with post-vital pulp therapy symptoms by retrying pulp-preserving procedures: A retrospective clinical study","authors":"Jin-Kyu Yi ,&nbsp;Ah-Rhim Seo","doi":"10.1016/j.jds.2024.08.002","DOIUrl":"10.1016/j.jds.2024.08.002","url":null,"abstract":"<div><h3>Background/purpose</h3><div>The occurrence of post-vital pulp therapy (VPT) symptoms is perplexing for dentists, and root canal treatment (RCT) is preferred for such conditions. Furthermore, managing post-VPT symptoms, rather than performing RCT, would preserve pulp vitality and enhance VPT outcomes. This study aimed to evaluate the efficacy of VPT retrials in preserving pulp vitality and substituting RCT in teeth with post-VPT symptoms.</div></div><div><h3>Materials and methods</h3><div>VPT was performed on the exposed pulp during caries removal in symptomatic and asymptomatic teeth. VPTs were repeated in teeth with post-VPT symptoms. This study screened multi-time-practiced VPT cases from a VPT-performed data pool. The presence of vital pulp tissue after minimized pulp resection (MPR) was a prerequisite for substituting RCT with VPT retrials. A total of 22 cases from 19 patients were included in this study. MPR was introduced to maximize the preservation of the vital pulp.</div></div><div><h3>Results</h3><div>After performing VPT, post-VPT symptoms occurred in pre-VPT asymptomatic teeth, or pre-VPT symptoms were modified in teeth with pre-VPT symptoms. The rate of pre-VPT irreversible pulpitis (IP), comprising symptomatic/asymptomatic IP, was 81.68%. The most prevalent post-VPT symptom was heightened sensitivity to thermal stimuli (68.2%), followed by spontaneous pain (45.5%). The post-VPT IP was 63.6%. VPT retrials resolved 90.9% of cases with post-VPT symptoms.</div></div><div><h3>Conclusion</h3><div>VPT retrials using MPR could enhance VPT outcomes and be a viable alternative to RCT for teeth with post-VPT symptoms.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 229-237"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel transnasal technique for the removal of nasally impacted mesiodens: A case report","authors":"Yi-Kai Huang,&nbsp;Meng-Ling Chiang,&nbsp;Jyh-Kwei Chen","doi":"10.1016/j.jds.2024.09.013","DOIUrl":"10.1016/j.jds.2024.09.013","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 710-712"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in 588 patients with oral lichen planus","authors":"Yu-Hsueh Wu ,&nbsp;Julia Yu-Fong Chang ,&nbsp;Yi-Pang Lee ,&nbsp;Yi-Ping Wang ,&nbsp;Andy Sun ,&nbsp;Chun-Pin Chiang","doi":"10.1016/j.jds.2024.11.014","DOIUrl":"10.1016/j.jds.2024.11.014","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Our previous study found that 21.9 %, 13.6 %, 7.1 %, 0.3 %, and 14.8 % of 352 oral lichen planus (OLP) patients have anemia, serum iron, vitamin B12, and folic acid deficiencies, and hyperhomocysteinemia, respectively. This study mainly evaluated the anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity in a large group of 588 OLP patients.</div></div><div><h3>Materials and methods</h3><div>The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 588 OLP patients were measured and compared with the corresponding levels in 588 age- and sex-matched healthy control subjects.</div></div><div><h3>Results</h3><div>We found that 148 (25.2 %), 99 (16.8 %), 60 (10.2 %), 7 (1.2 %), 124 (21.1 %), and 139 (23.6 %) OLP patients had blood Hb, serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity, respectively. Moreover, 588 OLP patients had significantly higher frequencies of blood Hb and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity than 588 healthy control subjects (all <em>P</em>-values &lt;0.001 except <em>P</em> = 0.023 for folic acid deficiency). Of 148 anemic OLP patients, 68 had normocytic anemia, 32 had iron deficiency anemia, 19 had thalassemia trait-induced anemia, 17 had pernicious anemia, 7 had macrocytic anemia other than pernicious anemia, and 5 had microcytic anemia other than iron deficiency anemia and thalassemia trait-induced anemia.</div></div><div><h3>Conclusion</h3><div>OLP patients have significantly higher frequencies of blood Hb and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum GPCA positivity than healthy control subjects.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 660-666"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significant association of oral health-related quality of life with mental depression in middle-aged and older Taiwanese adults","authors":"Dun-Yu Hsu ,&nbsp;Wu-Chien Chien ,&nbsp;Da-Yo Yuh ,&nbsp;Ling-Yu Kung ,&nbsp;Yuan-Wu Chen","doi":"10.1016/j.jds.2024.07.027","DOIUrl":"10.1016/j.jds.2024.07.027","url":null,"abstract":"<div><h3>Background/purpose</h3><div>With the gradual aging of the population, oral health has emerged as a critical concern alongside mental well-being. This study endeavored to investigate the relationship between oral health-related quality of life (OHRQoL) and mental depression in middle-aged and older population.</div></div><div><h3>Materials and methods</h3><div>Based on the Taiwan Longitudinal Study on Aging in 2015, 7631 participants were enrolled. OHRQoL was assessed utilizing the Taiwan version of the Oral Health Impact Profile questionnaire, stratifying individuals into five categories (excellent, good, fair, poor, and very poor). The excellent OHRQoL group was regarded as the reference group. Depression status was evaluated using the 10-item Center for the Epidemiological Studies of Depression Short Form questionnaire. Descriptive statistics and Pearson's chi square test were applied to elucidate the demographic characteristics and the differences among the five OHRQoL groups, respectively. Multivariable logistic regression was applied to elucidate the association of OHRQoL with depression after controlling for confounding factors.</div></div><div><h3>Results</h3><div>After controlling for covariates such as age, sex, marital status, living status, residency status, religion, level of physical activity, and pressures arising from personal or familial concerns, the adjusted ORs of experiencing mental depression were 1.45 (95% CI: 1.198–1.760, <em>P</em> &lt; 0.001), 2.25 (95% CI: 1.791–2.829, <em>P</em> &lt; 0.001), 3.88 (95% CI: 2.730–5.525, <em>P</em> &lt; 0.001), and 6.87 (95% CI: 3.116–15.129, <em>P</em> &lt; 0.001) for the good, fair, poor, and very poor OHRQoL groups, respectively, which demonstrated a gradually increased relationship.</div></div><div><h3>Conclusion</h3><div>Oral health-related quality of life was negatively associated with mental depression in middle-aged and older adults.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 261-269"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sialolithiasis of the right submandibular gland incidentally found on the panoramic radiograph","authors":"Feng-Chou Cheng,&nbsp;Mu-Hsiung Chen,&nbsp;Chia-Hung Chang,&nbsp;Chun-Pin Chiang","doi":"10.1016/j.jds.2024.10.026","DOIUrl":"10.1016/j.jds.2024.10.026","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 683-685"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current challenges of dental laboratory in Taiwan: The perspectives from a senior certified dental technician in a dental laboratory attached to a teaching hospital","authors":"Feng-Chou Cheng ,&nbsp;Wei-Chun Lin ,&nbsp;Chun-Pin Chiang","doi":"10.1016/j.jds.2024.10.004","DOIUrl":"10.1016/j.jds.2024.10.004","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 678-682"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning system for the differential diagnosis of oral mucosal lesions through clinical photographic imaging","authors":"An-Yu Su ,&nbsp;Ming-Long Wu ,&nbsp;Yu-Hsueh Wu","doi":"10.1016/j.jds.2024.10.019","DOIUrl":"10.1016/j.jds.2024.10.019","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Oral mucosal lesions are associated with a variety of pathological conditions. Most deep-learning-based convolutional neural network (CNN) systems for computer-aided diagnosis of oral lesions have typically concentrated on determining limited aspects of differential diagnosis. This study aimed to develop a CNN-based diagnostic model capable of classifying clinical photographs of oral ulcerative and associated lesions into five different diagnoses, thereby assisting clinicians in making accurate differential diagnoses.</div></div><div><h3>Materials and methods</h3><div>A set of clinical images were selected, including 506 images of five different diagnoses. The images were pre-processed and randomly divided into two sets for training and testing the CNN model. The model architecture was composed of convolutional layers, batch normalization layers, max pooling layers, the dropout layer and fully-connected layers. Evaluation metrics included weighted-precision, weighted-recall, weighted-F1 score, average specificity, Cohen’s Kappa coefficient, normalized confusion matrix and AUC.</div></div><div><h3>Results</h3><div>The overall performance for the image classification showed a weighted-precision of 88.8%, a weighted-recall of 88.2%, a weighted-F1 score of 0.878, an average pecificity of 97.0%, a Kappa coefficient of 0.851, and an average AUC of 0.985.</div></div><div><h3>Conclusion</h3><div>The model achieved a decent classification performance (overall AUC=0.985), showing the capacity to discern between benign and malignant potential lesions, and laid the foundation of a novel tool that can help clinical differential diagnosis of oral mucosal lesions. The main challenges were the small and imbalanced dataset. Enlarging the minority classes, incorporating more oral mucosal lesion diagnoses, employing transfer learning and cross-validation might be included in future works to optimize the image classification model.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 54-60"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of periodontal bone loss in panoramic radiographs through artificial intelligence analysis","authors":"Chia-Tze Kao,&nbsp;Chih-Jen Tseng,&nbsp;Ming-Che Tsai,&nbsp;Chien-Ning Huang","doi":"10.1016/j.jds.2024.09.031","DOIUrl":"10.1016/j.jds.2024.09.031","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 1","pages":"Pages 698-700"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}