Journal of Dental Sciences最新文献

{"title":"The dental clinic on the postcard with the theme of Taiwan street scene during the Japanese colonial period: The story of a Japanese immigrant, Dr. Akira Sugiyama","authors":"Feng-Chou Cheng, Ling-Hsia Wang, Chun-Pin Chiang","doi":"10.1016/j.jds.2025.04.029","DOIUrl":"10.1016/j.jds.2025.04.029","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1969-1971"},"PeriodicalIF":3.4,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The standardization of oral health screening survey in Taiwan","authors":"Feng-Chou Cheng , Ling-Hsia Wang , Chun-Pin Chiang","doi":"10.1016/j.jds.2025.04.027","DOIUrl":"10.1016/j.jds.2025.04.027","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1912-1914"},"PeriodicalIF":3.4,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3,4-methylenedioxymethamphetamine induces reactive oxygen species-mediated autophagy and thioredoxin-interactive protein/nucleotide-binding domain, leucine-rich containing family, pyrin domain-containing-3 inflammasome activation in dental pulp stem cells","authors":"Shih-Yu Lee ,&nbsp;Shang-Wen Chiu ,&nbsp;I-Hsun Li ,&nbsp;Wei-Cheng Tsai ,&nbsp;Chung-Hsing Li","doi":"10.1016/j.jds.2025.04.025","DOIUrl":"10.1016/j.jds.2025.04.025","url":null,"abstract":"<div><h3>Background/purpose</h3><div>3,4-methylenedioxymethamphetamine (MDMA) is a synthetic substituted amphetamine. Research primarily focuses on its neurotoxicity and psychological effects, while studies examining its impact on mesenchymal stem cells (MSCs) and dental pulp stem cells (DPSCs) are relatively limited. This study investigated the cytotoxicity and molecular mechanisms of MDMA in DPSCs.</div></div><div><h3>Materials and methods</h3><div>Cell viability, apoptosis, autophagy, immunophenotype, reactive oxygen species (ROS), and the related signaling pathways were analyzed using a cell counting kit, Western blot, flow cytometry, and 2′,7′-dichlorofluorescein diacetate (DCFH-DA) dye after treating DPSCs with indicated concentrations of MDMA.</div></div><div><h3>Results</h3><div>MDMA significantly decreased cell viability and increased cleaved poly adenosine diphosphate-ribose polymerase (PARP), cleaved caspase-8, cleaved caspase-3, and Bcl-2-associated X protein (Bax), while reducing B-cell lymphoma 2 (Bcl-2). Annexin V and 7-aminoactinomycin D (7-AAD) flow cytometry showed that these cells underwent early apoptosis without altering MSCs’ immunophenotypic properties. MDMA also induced ROS accumulation and nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing-3 (NLRP3) inflammasome activation. Autophagy activation was observed with adenosine monophosphate-activated protein kinase (AMPK) activation, protein kinase B (AKT) inactivation, and mammalian target of rapamycin (mTOR) suppression. Autophagy inhibitor chloroquine (CQ) attenuated MDMA-induced cell death, suggesting that excessive autophagy contributes to cell damage.</div></div><div><h3>Conclusion</h3><div>MDMA induces ROS-mediated autophagic cell death and thioredoxin-interacting protein (TXNIP)/NLRP3 inflammasome activation, causing detrimental cell damage. The historical roots of drug addiction should be considered when modifying dental approaches for patients with a history of MDMA use, as well as in the screening of DPSCs donors and patients undergoing stem cell therapy.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1782-1791"},"PeriodicalIF":3.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychosomatic concepts in nociplastic pain: The case of burning mouth syndrome","authors":"Takayuki Suga,&nbsp;Akira Toyofuku","doi":"10.1016/j.jds.2025.04.020","DOIUrl":"10.1016/j.jds.2025.04.020","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1972-1973"},"PeriodicalIF":3.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenoid ameloblastoma in the maxilla","authors":"Yu-Min Lin,&nbsp;Yuk-Kwan Chen,&nbsp;Wen-Chen Wang,&nbsp;Chih-Huang Tseng","doi":"10.1016/j.jds.2025.04.013","DOIUrl":"10.1016/j.jds.2025.04.013","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1974-1976"},"PeriodicalIF":3.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the relation among the needle insertion plane, occlusal plane, mandibular foramen, and mandibular lingula for inferior alveolar nerve block","authors":"Han-Sheng Chen ,&nbsp;Kun-Jung Hsu ,&nbsp;Pei-Jung Chen ,&nbsp;Hui-Na Lee ,&nbsp;Jen Hao Chen ,&nbsp;Chun-Ming Chen","doi":"10.1016/j.jds.2025.04.016","DOIUrl":"10.1016/j.jds.2025.04.016","url":null,"abstract":"<div><h3>Background/purpose</h3><div>The success rates and incidence of positive blood aspiration during inferior alveolar nerve blocks (IANB) vary. Understanding the relative positions of the mandibular foramen (MF), mandibular lingula (ML), and occlusal plane (OP) is crucial for the effectiveness and safety of IANB. This study evaluates the relationship among needle insertion levels, ML, and OP for IANB.</div></div><div><h3>Materials and methods</h3><div>Cone-beam computed tomography images of 90 participants were analyzed to measure ML and MF distances relative to OP. Participants were categorized into skeletal classes (I, II, and III). The distances from ML to the anesthetic needle positioned 5, 6, 7, 8, 9, and 10 mm above OP were assessed. Comparisons based on gender and skeletal classes were conducted, and correlations among variables were evaluated.</div></div><div><h3>Results</h3><div>The MF and ML were located below OP in 72 (40.0 %) and 5 (2.8 %) sides, respectively. Class II had the highest proportion of MF below OP (16.67 %), followed by Class III (13.33 %) and Class I (10 %). When the needle was inserted 5 mm and 10 mm above OP, ML was below the insertion plane in 27 (15 %) and 116 (64.4 %) sides, respectively. ML-OP distances were significantly greater in Class III (9.75 mm) and Class I (9.62 mm) than in Class II (7.29 mm).</div></div><div><h3>Conclusion</h3><div>Class II exhibited significantly smaller ML-OP and MF-OP distances than Class I and Class III. The needle should be inserted parallel to OP and positioned approximately 6–7 mm above OP for improved safety and anesthesia efficacy.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1792-1801"},"PeriodicalIF":3.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenomatoid odontogenic tumor arising from a dentigerous cyst in an elderly patient: An unusual presentation","authors":"Kyu-Young Oh","doi":"10.1016/j.jds.2025.04.021","DOIUrl":"10.1016/j.jds.2025.04.021","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1977-1979"},"PeriodicalIF":3.4,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital transformation and talent needs in the Greater China region: Additional perspectives from mainland China","authors":"Hongnan Ye","doi":"10.1016/j.jds.2025.04.023","DOIUrl":"10.1016/j.jds.2025.04.023","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1980-1981"},"PeriodicalIF":3.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masson's tumor of masticatory space: Detection in medical images","authors":"Pei-Ju Chiang,&nbsp;Yang-Che Wu,&nbsp;Kazuyo Kuribayashi Sato,&nbsp;Chun-Yu Ho","doi":"10.1016/j.jds.2025.04.012","DOIUrl":"10.1016/j.jds.2025.04.012","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1985-1987"},"PeriodicalIF":3.4,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel radiographic pattern of maxillary periostitis induced by endodontic inflammation: A case report","authors":"Pai-Chun Huang,&nbsp;I-Hao Su,&nbsp;Meng-Ling Chiang,&nbsp;Jyh-Kwei Chen","doi":"10.1016/j.jds.2025.04.018","DOIUrl":"10.1016/j.jds.2025.04.018","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 3","pages":"Pages 1982-1984"},"PeriodicalIF":3.4,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144366624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}