Journal of Dental Sciences最新文献

{"title":"Digital transformation and talent needs in the Greater China region: The perspective of a regional sales manager with international expertise in the dental materials manufacturing","authors":"Wei-Chun Lin, Feng-Chou Cheng, Becky Tung, Chun-Pin Chiang","doi":"10.1016/j.jds.2025.01.021","DOIUrl":"10.1016/j.jds.2025.01.021","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1322-1324"},"PeriodicalIF":3.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The study of three-dimensional smile changes on orofacial morphology","authors":"Johnson Hsin-Chung Cheng ,&nbsp;Yu-Chien Hsu ,&nbsp;Od Bayarsaikhan","doi":"10.1016/j.jds.2025.01.010","DOIUrl":"10.1016/j.jds.2025.01.010","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Traditionally, two-dimensional (2D) frontal and lateral facial views have provided an incomplete understand true three-dimensional (3D) relationships. This study aimed to investigate the 3D changes in orofacial soft tissues during smiling and to examine the influence of craniofacial and dental morphology on these changes.</div></div><div><h3>Materials and methods</h3><div>131 individuals aged 18–30 with attractive facial features were recruited. Rest and posed smile 3D facial photos captured by 3D camera and cone-beam computed tomography (CBCT) scans were taken. Data were recorded and analyzed in rest, smile images, and smiling change measurements, including 23 landmarks, 11 linear, and 6 angular measurements. Statistical methods were used to analyze the frequency distribution, the significant difference between rest and smile variables, and the relationship between craniofaciodental tissue and 3D smile changes.</div></div><div><h3>Results</h3><div>The study involved 65 males (mean age 23.5 ± 3.2 years) and 66 females (mean age 22.5 ± 1.5 years). The soft tissue landmarks changed during smiling reveals that 21 landmarks in z-plane, 22 landmarks in y-plane, and 15 landmarks in x-plane landmarks showed significant differences. In addition, a significant correlation was noted between upper lip length (sn-uli) (r = 0.46, <em>P</em> = 0.057), lower lip length (lls-SB) (r = 0.44, <em>P</em> = 0.022), and the hard tissue measurement Id-Me.</div></div><div><h3>Conclusion</h3><div>The significant 3D change of soft tissue landmarks during smiling occurs mostly in z and y-plane, rather than x-plane. Clinically, all dimensions should be considered in orthodontic diagnosis and treatment planning, especially in the z plane the change cannot be seen in the traditional 2D analysis.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1148-1157"},"PeriodicalIF":3.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of infiltration anesthesia with 4 % Articaine and block anesthesia with 2 % Lidocaine in the mandibular third molar extraction","authors":"Nai-Chih Huang ,&nbsp;Hao-Hueng Chang ,&nbsp;Chun-Pin Lin","doi":"10.1016/j.jds.2025.01.018","DOIUrl":"10.1016/j.jds.2025.01.018","url":null,"abstract":"<div><h3>Background/Purpose</h3><div>Articaine is a dental anesthetic that has been developed and widely used in recent years. This study aimed to compare the anesthetic efficacy and safety of infiltration anesthesia with 4 % Articaine (with 1:100,000 epinephrine) and block anesthesia with 2 % Lidocaine (with 1:100,000 epinephrine) in the mandibular third molar extraction.</div></div><div><h3>Materials and methods</h3><div>This prospective, randomized, split-mouth clinical trial was planned to involve 30 adults with the bilateral mandibular third molars. Participants were randomly assigned to receive 4 % Articaine (Articaine group) by infiltration anesthesia on one side and 2 % Lidocaine (Lidocaine group) by block anesthesia on the opposite side. Parameters such as the heart rate, blood pressure, oxygen saturation, anesthetic usage, operation duration, pain score, satisfaction, and adverse events were recorded and analyzed.</div></div><div><h3>Results</h3><div>Finally, 26 participants receiving the bilateral mandibular third molar extraction were included. There were no significant differences in the heart rate, blood pressure, oxygen saturation, and maximum fluctuations during the extraction procedure between the two groups, except the maximum heart rate fluctuation showing statistical significance. Additionally, the amount of anesthetic used was significantly lower in the Articaine group (1.5 ± 0.4 cartridges) than in the Lidocaine group (2.2 ± 0.5 cartridges) (<em>P</em> &lt; 0.001). There were no significant differences in the operation duration, pain score, and satisfaction between the two groups, and no adverse events were reported in either group.</div></div><div><h3>Conclusion</h3><div>Using 4 % Articaine for infiltration anesthesia offers comparable pain control to 2 % Lidocaine for block anesthesia in the mandibular third molar extraction surgery. Using 4 % Articaine can safely achieve similar pain control with lower doses and less invasive anesthesia techniques.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1139-1147"},"PeriodicalIF":3.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Submandibular schwannoma arising from the hypoglossal nerve radiologically masquerading as submandibular gland tumor","authors":"Toshinori Iwai,&nbsp;Satomi Sugiyama,&nbsp;Soichiro Ishikawa,&nbsp;Kenji Mitsudo","doi":"10.1016/j.jds.2025.01.017","DOIUrl":"10.1016/j.jds.2025.01.017","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1325-1327"},"PeriodicalIF":3.4,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severely swollen upper lip associated with methicillin-resistant Staphylococcus aureus infection","authors":"Po-Yuan Jeng,&nbsp;Chia-Tze Kao,&nbsp;Jiiang-Huei Jeng,&nbsp;Cheng-Mei Yang","doi":"10.1016/j.jds.2025.01.015","DOIUrl":"10.1016/j.jds.2025.01.015","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1328-1330"},"PeriodicalIF":3.4,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Removing filling material during secondary root canal therapy: An update","authors":"Karl-Thomas Wrbas,&nbsp;Kaveh Nasiri,&nbsp;Maya Doychinova","doi":"10.1016/j.jds.2025.01.016","DOIUrl":"10.1016/j.jds.2025.01.016","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1331-1332"},"PeriodicalIF":3.4,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoxia amplifies arecoline-induced invasion and metastasis in oral squamous cell carcinoma – Insights into TGF-β1 signaling and collagen production","authors":"Feng-Cheng Wu ,&nbsp;Chun-Chan Ting ,&nbsp;Jiiang-Huei Jeng ,&nbsp;Hangshen Chen ,&nbsp;Yong-Deok Kim ,&nbsp;Chia-Chen Wu ,&nbsp;Yu-Hsun Kao ,&nbsp;Chih-Huang Tseng ,&nbsp;Yuk-Kwan Chen ,&nbsp;Toru Ogasawara ,&nbsp;Kazuto Hoshi ,&nbsp;Wen-liang Lo ,&nbsp;Tetsu Takahashi ,&nbsp;Yi-Hsin Yang ,&nbsp;Edward Chengchuan Ko","doi":"10.1016/j.jds.2024.12.026","DOIUrl":"10.1016/j.jds.2024.12.026","url":null,"abstract":"<div><h3>Background/Purpose</h3><div>Betel quid chewing is a major risk factor for oral squamous cell carcinoma (OSCC), largely due to arecoline, a key alkaloid. Hypoxia, common in the tumor microenvironment, also influences cancer progression. This study investigated the combined effects of arecoline and hypoxia on proliferation, migration, and protein expression in tongue squamous cell carcinoma (SCC-25) cells, focusing on the TGF-β1 signaling pathway and type I collagen production.</div></div><div><h3>Materials and methods</h3><div>SCC-25 cells were treated with arecoline and incubated for 24 h under normoxia or hypoxia. Cytotoxicity assays and Western blotting were performed to assess cell viability and protein expression.</div></div><div><h3>Results</h3><div>At 2.5 μg/mL, arecoline enhanced SCC-25 cell proliferation under normoxia, while hypoxia suppressed this effect. Arecoline significantly promoted cell migration that was further amplified by hypoxia. Western blotting revealed that arecoline upregulated TGF-β1, Smad2/3, phosphorylated Smad2/3, and type I collagen. Under hypoxia, HIF1-α expression increased along with TGF-β1 and type I collagen, indicating that hypoxia enhances arecoline-induced collagen production through TGF-β1 signaling.</div></div><div><h3>Conclusion</h3><div>Arecoline stimulates SCC-25 cell proliferation and migration, with hypoxia amplifying these effects by promoting TGF-β1 signaling and type I collagen production. These findings suggest that betel quid consumption, in combination with hypoxia, may exacerbate the invasion and metastasis of OSCC.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1129-1138"},"PeriodicalIF":3.4,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taking preclinical dental education to another level with mixed reality technology","authors":"Scott David Pelok,&nbsp;Theresa Roma Jasinevicius,&nbsp;Ilser Turkyilmaz","doi":"10.1016/j.jds.2025.01.011","DOIUrl":"10.1016/j.jds.2025.01.011","url":null,"abstract":"","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1333-1334"},"PeriodicalIF":3.4,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in oral lichen planus patients with vitamin B12 deficiency","authors":"Yu-Hsueh Wu ,&nbsp;Julia Yu-Fong Chang ,&nbsp;Yi-Pang Lee ,&nbsp;Yi-Ping Wang ,&nbsp;Andy Sun ,&nbsp;Chun-Pin Chiang","doi":"10.1016/j.jds.2025.01.007","DOIUrl":"10.1016/j.jds.2025.01.007","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Our previous study found that 60 of 588 oral lichen planus (OLP) patients have vitamin B12 deficiency. This study assessed whether the vitamin B12-deficient OLP (B12D/OLP) patients had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than healthy control subjects and evaluated whether all B12D/OLP patients had pernicious anemia (PA).</div></div><div><h3>Materials and methods</h3><div>The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 60 B12D/OLP patients and 588 healthy control subjects were measured and compared.</div></div><div><h3>Results</h3><div>We found that 60 B12D/OLP patients had significantly lower mean blood Hb and serum iron, vitamin B12, and folic acid levels as well as significantly higher mean corpuscular volume (MCV) and mean serum homocysteine level than 588 healthy control subjects (all <em>P</em>-values &lt;0.01). Moreover, 60 B12D/OLP patients had significantly higher frequencies of macrocytosis (55.0 %), blood Hb (68.3 %) and serum iron (31.7 %) and vitamin B12 (100.0 %) deficiencies, hyperhomocysteinemia (91.7 %), and serum GPCA positivity (66.7 %) than 588 healthy control subjects (all <em>P</em>-values &lt;0.001). The four most common types of anemia in 41 anemic B12D/OLP patients were PA (17 patients, 41.5 %), normocytic anemia (12 patients, 29.3 %), iron deficiency anemia (6 patients, 14.6 %), and macrocytic anemia other than PA (5 patients, 12.2 %).</div></div><div><h3>Conclusion</h3><div>The B12D/OLP patients have significantly higher frequencies of macrocytosis, blood Hb and serum iron and vitamin B12 deficiencies, hyperhomocysteinemia, and serum GPCA positivity than healthy control subjects. Only 17 (28.3 %) of 60 B12D/OLP patients have PA.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1102-1109"},"PeriodicalIF":3.4,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scientometric study on research trends and characteristics of burning mouth syndrome","authors":"Wei Liu ,&nbsp;Ying Zhang ,&nbsp;Qi Zhu ,&nbsp;Lan Wu","doi":"10.1016/j.jds.2025.01.009","DOIUrl":"10.1016/j.jds.2025.01.009","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Burning mouth syndrome (BMS) is a chronic condition characterized by intraoral burning sensation and orofacial pain but without oral mucosal lesions. The purpose of this study was to analyze the scientometric characteristics and research trends of BMS.</div></div><div><h3>Materials and methods</h3><div>All the papers on BMS were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and 2015–2024 in the analysis of research trends.</div></div><div><h3>Results</h3><div>There were 924 papers on BMS, with total citations of 24,024 and the <em>h</em> index of 76. The related disorders of BMS were depression, xerostomia, pain, anxiety, glossodynia, taste disorder, nociception, paresthesia, analgesia, sleep disorder, diabetes mellitus, and neuralgia. Clonazepam was most common pharmacotherapy for BMS. After 2015, pharmacologic keywords including drug safety, aripiprazole, duloxetine, folic acid, hydrocortisone, and pregabalin were more frequent. Low level laser therapy, acupuncture, and cognitive behavioral therapy were the emerging nonpharmacologic strategies for BMS. Moreover, laboratory investigations on biomarkers, blood, genetics, interleukin 6, and tumor necrosis factor were more common. Various questionnaires, comorbidity, complication, anemia, hypertension, diabetes mellitus, and sleep were also more concerned after 2015.</div></div><div><h3>Conclusion</h3><div>This scientometric study elucidated the current scenario and research trends of BMS, and would help in improving in reciprocal collaboration and communication for investigations on this condition.</div></div>","PeriodicalId":15583,"journal":{"name":"Journal of Dental Sciences","volume":"20 2","pages":"Pages 1252-1256"},"PeriodicalIF":3.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}