Journal of Cosmetic Dermatology最新文献

{"title":"The Role of Photobiomodulation and Light Therapy in Enhancing Burn Wound Recovery","authors":"Edwin Chrabieh,&nbsp;Mahmoud El Hajj,&nbsp;Saif Emsieh,&nbsp;Hazem Omaish,&nbsp;Mazen Kurban","doi":"10.1111/jocd.71040","DOIUrl":"https://doi.org/10.1111/jocd.71040","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Photobiomodulation (PBM) is a non-invasive treatment using low-intensity red or near-infrared light to stimulate tissue repair and reduce inflammation. While used in aesthetic and rehabilitative medicine, its role in burn wound healing remains underexplored. Given biological parallels between post-injury remodeling and cosmetic rejuvenation, a systematic review of PBM in burn care is warranted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To evaluate the clinical effectiveness, safety, and outcomes of PBM—such as low-level laser and light-emitting diode (LED) therapy—in human burn patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic search of Ovid MEDLINE, Embase, and LILACS was conducted up to 2024. The MEDLINE search was conducted via Ovid MEDLINE, which includes all records indexed in PubMed, ensuring comprehensive coverage of the biomedical literature. Studies were included if they investigated PBM in human burn patients and reported at least one clinical outcome. Two reviewers independently screened studies; a third resolved conflicts. Risk of bias was assessed using a modified Cochrane tool. Due to outcome heterogeneity, narrative synthesis was performed. A binary heatmap visualized patterns across six domains: wound area, healing time, pain (VAS), scar quality (VSS), patient satisfaction, and adverse events.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seven studies involving 190 patients were included. Healing time and pain (VAS) were most frequently reported, followed by wound area and scar quality. Only one study assessed patient satisfaction, and adverse events were inconsistently reported. PBM showed promising effects, including reduced healing time and pain. However, limited comparable data precluded meta-analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>PBM appears to be a promising adjunct in burn care, with benefits in healing, pain, and scar remodeling. However, methodological limitations, dosing variability, and inconsistent outcome reporting limit conclusions. High-quality, standardized trials using validated patient-reported outcomes are needed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148616633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Intensity Focused Ultrasound for Botulinum Toxin-Induced Ptosis: A Retrospective Pilot Case Series","authors":"Mojtaba Nasimi,&nbsp;Farideh Nasiri","doi":"10.1111/jocd.71109","DOIUrl":"https://doi.org/10.1111/jocd.71109","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Botulinum toxin-induced ptosis is a recognized complication of aesthetic injections that may adversely affect cosmetic outcomes and patient satisfaction. Pharmacologic management is limited and primarily aims to provide temporary elevation of the upper eyelid through stimulation of Müller's muscle. High-intensity focused ultrasound (HIFU) has established applications in facial tissue tightening and may represent a potential non-pharmacologic treatment option.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To evaluate the clinical outcomes of botulinum toxin-induced ptosis treated with HIFU using the ULTRAcel Q+ system.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This retrospective pilot case series included five consecutive patients with botulinum toxin-induced ptosis treated using a standardized HIFU protocol with the ULTRAcel Q+ system (3-mm dot handpiece, energy level 0.7, 12 shots). Clinical outcomes were evaluated using standardized photographs obtained under controlled imaging conditions. Margin Reflex Distance 1 (MRD1), defined as the distance between the corneal light reflex and the upper eyelid margin in primary gaze. Eyebrow position was also evaluated by comparing brow height relative to the supraorbital rim and facial symmetry. Both were measured at baseline, immediately after treatment, and during follow-up through Day 21.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Five patients (4 females, 1 male; mean age 38.4 years) were included. All had received Dysport injections (130–150 units) to the glabella, forehead, and crow's feet regions. Ptosis onset occurred 3–7 days after injection. HIFU was performed 3–6 days after symptom onset. Mean MRD1 increased from 0.76 mm at baseline to 1.98 mm immediately after treatment, 2.30 mm at Day 7, 4.18 mm at Day 14, and 4.44 mm at Day 21. Three patients presented with isolated eyelid ptosis, whereas two had combined eyelid and eyebrow ptosis. All patients demonstrated complete clinical resolution by Day 14. Mild transient procedural pain occurred during treatment, and no long-term treatment-related adverse events were observed.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In this retrospective pilot case series, HIFU using the ULTRAcel Q+ system was associated with complete clinical resolution of botulinum toxin-induced ptosis by Day 14 and was well tolerated. Unlike pharmacologic agents such as oxymetazoline, which temporarily elevate the eyelid throu","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71109","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148616418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Oral Herbal Supplementation on Human Skin Aging: A Systematic Review of Clinical Trials","authors":"Gisela Meydilin Sanjaya,&nbsp;Brilian Veda Kartika Putri,&nbsp;Hany Anneke,&nbsp;Nayla Majeda Alfarafisa,&nbsp;Astrid Feinisa Khairani,&nbsp;Nur Atik","doi":"10.1111/jocd.71094","DOIUrl":"https://doi.org/10.1111/jocd.71094","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Skin aging, characterized by wrinkles, decreased elasticity, and dryness, is both a public health and esthetic issue, affecting most adults and leading to lowered quality of life and higher healthcare costs. While topical treatments are common, systemic approaches are gaining interest for their potential to enhance skin hydration, elasticity, and barrier function. Nonetheless, the effects of oral herbal supplements remain less examined.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This systematic review evaluated the effectiveness of oral herbal supplements in reducing skin aging in humans, focusing on elasticity, hydration, wrinkle depth, and antioxidant activity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Randomized controlled trials (RCTs) were identified through structured database searches (March–August 2025). Twelve RCTs published between 2020 and 2025 met the inclusion criteria, involving adults who received oral herbal supplements versus placebo or standard care. Outcomes measured included skin elasticity, hydration, wrinkle depth, smoothness, antioxidant capacity, and inflammatory markers. Quality assessment using the Cochrane RoB 2 tool indicated that all 12 RCTs were judged as having <i>some concerns</i> of bias.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Interventions included <i>Glycine max</i>, bilberry, cranberry, Hydrangea serrata, Pycnogenol, and others. Most studies reported significant improvements in dermatological outcomes. Proposed mechanisms involve antioxidant activity, anti-inflammatory effects, collagen synthesis, barrier restoration, photoprotection, DNA repair, and microbiome modulation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In conclusion, oral herbal supplements show promising potential in improving skin aging outcomes by targeting multiple biological pathways. Further research with larger populations, longer durations, and biomarker-based endpoints is needed to confirm efficacy and support standardized use in dermatology and esthetic medicine.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148616097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UniPolar Radiofrequency for Treatment of Facial Aging Signs and Skin Laxity","authors":"Krenar Dobroshi,&nbsp;Iva Stoilova,&nbsp;Bekim Ismaili,&nbsp;Marija Glavash Dodov,&nbsp;Renata Slaveska Raichki","doi":"10.1111/jocd.71102","DOIUrl":"https://doi.org/10.1111/jocd.71102","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Radiofrequency (RF) technologies are widely used for noninvasive skin rejuvenation. Unlike other RF technologies, unipolar RF emits an electromagnetic field that produces controlled heat within the adjacent area, promoting collagen remodeling and improving the visible signs of skin aging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study evaluated the safety and efficacy of unipolar RF in improving facial skin laxity and wrinkles.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis was conducted on <i>n</i> = 93 patients treated with a unipolar RF applicator. Clinical outcomes were assessed using the Global Aesthetic Improvement Scale (GAIS) and Modified Fitzpatrick Wrinkle and Elastosis Scale (MFWS). Blinded evaluators compared pre- and posttreatment photographs, and patient-reported outcomes, treatment-associated pain, and overall satisfaction were also analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>GAIS showed overall improvement (mean score 1.9 ± 0.5) and MFWS values decreased following treatments (mean change −0.3 ± 0.3; <i>p</i> &lt; 0.001). A significant negative correlation between GAIS and MFWS reduction (<i>p</i> &lt; 0.001) as well as a positive correlation for higher treatment numbers and GAIS outcome were found. Patients rated their satisfaction as “satisfied” to “much satisfied.” No serious adverse events were reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Unipolar radiofrequency demonstrated significant improvements in facial skin laxity and wrinkles with minimal discomfort and a high safety profile.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148616098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Discourse on Menopausal Skin Management: A YouTube Infodemiology Study of Treatment Perceptions, Sentiment, and Unmet Needs Across 43 954 Viewer Comments","authors":"Esin Diremsizoglu,&nbsp;Emre Akif Arslan,&nbsp;Abdullah Demirbas,&nbsp;Sabrina G. Fabi","doi":"10.1111/jocd.71101","DOIUrl":"https://doi.org/10.1111/jocd.71101","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Menopausal skin changes carry significant psychosocial burden yet remain clinically under-addressed. As women increasingly turn to digital platforms for information and peer experience, YouTube viewer comments represent an underexplored source of real-world treatment perceptions at scale.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Cross-sectional infodemiology study using the YouTube Data API v3 (14 March 2026). 342 videos yielded 43 954 analyzable comments after automated cleaning (350-comment/video cap). Videos were classified into four content-type categories (Cohen's κ = 0.934). A 13-category management subcorpus (<i>n</i> = 10 861; 24.7% of full corpus) was constructed by pre-specified keyword matching.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study corpus showed predominantly positive sentiment (59.6% positive, 19.1% negative; median 0.36, IQR 0.00–0.73). Hormone replacement therapy (HRT) dominated the management subcorpus (54.8%) yet generated the lowest sentiment of any category (median 0.10; 30.2% negative), differing significantly from all others (<i>p</i> &lt; 0.001). Alternative approaches (median 0.72; 77.7% positive) and supplements (median 0.50; 74.6% positive) attracted the highest positivity. Personal/lifestyle content generated higher positivity (median 0.59; 70.6%) than clinician content (median 0.32; 57.7%; <i>p</i> &lt; 0.001). Following the FDA's November 2025 HRT boxed warning removal, a higher proportion of positive HRT comments was observed in the post-announcement period (53.1% vs. 50.5%; <i>p</i> = 0.126) over the 4.5-month available window. A negative temporal trend was observed over 116 months (Spearman ρ = −0.424, <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>HRT generates the most negative public commentary of any management category, while supplements and alternative approaches attract positivity disproportionate to their evidence base. Clinician content elicits lower viewer positivity than lifestyle creators. Dermatologists should address HRT safety misconceptions and increase online representation of evidence-based procedural options.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148615968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy and Safety of Tissue Grafting Versus ReCell Autologous Cell Suspension in Stable Vitiligo: A 12-Month Retrospective Study","authors":"Dihui Lai,&nbsp;Jianchun Hao,&nbsp;Xueya Tong,&nbsp;Maoying Wei,&nbsp;Xiaoju Xian,&nbsp;Xintong Chang,&nbsp;Jing Ma,&nbsp;Shaowei Cheng","doi":"10.1111/jocd.71086","DOIUrl":"https://doi.org/10.1111/jocd.71086","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Vitiligo surgery is often the last resort for treatment-resistant lesions with stable conditions. Between tissue grafting (suction blister epidermal grafting [SBEG] and ultra-thin split-thickness skin grafting [UT-STSG]) and cellular grafting (ReCell), large-scale comparative data are lacking.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a comprehensive retrospective cohort study of 277 patients (1501 lesions) undergoing tissue grafting (<i>n</i> = 111, 451 lesions), or ReCell (<i>n</i> = 166, 1050 lesions) for stable vitiligo between December 2023 and March 2026. The primary endpoint was 12-month repigmentation rate, with secondary outcomes including adverse events. Predictors of treatment success were identified via binary logistic regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At 12 months, ReCell achieved superior repigmentation compared with tissue grafting (median 89.7% vs. 60.1%, <i>p</i> &lt; 0.001), with ≥ 75% repigmentation in 62.8% versus 24.0% of lesions. Stratified analysis revealed site-dependent effects: no significant difference was observed for facial/trunk lesions (98.6% vs. 92.9%, <i>p</i> = 0.562) or acral lesions (46.9% vs. 50.8%, <i>p</i> = 0.077), whereas ReCell was superior for peri-mucosal sites (81.0% vs. 50.0%, <i>p</i> = 0.028). In nonsegmental vitiligo, ReCell outperformed tissue grafting (87.5% vs. 53.9%, <i>p</i> &lt; 0.001), with no difference in segmental disease (95.0% vs. 81.3%, <i>p</i> = 0.374). Adjuvant 308-nm excimer lamp therapy (24–47 sessions) increased success fourfold (OR = 3.90, <i>p</i> = 0.002). ReCell demonstrated superior safety (2.4% vs. 16.2% adverse events, <i>p</i> = 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>ReCell may offer superior 12-month repigmentation and safety for stable nonsegmental, non-acral vitiligo. Traditional tissue grafting retains viability for limited lesions and resource-limited settings. Postoperative phototherapy is crucial for optimal outcomes. These real-world data are hypothesis-generating; prospective randomized trials with extended follow-up are needed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71086","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148615969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Tattoo Removal Sessions With Picosecond Lasers: Development and Validation of a Novel Clinical Scale With Machine Learning Techniques","authors":"Valerio Pedrelli,&nbsp;Emanuele Tauro,&nbsp;Matteo Tretti Clementoni,&nbsp;Alessandra Zevini,&nbsp;Riccardo Barini,&nbsp;Enrico Gianluca Caiani","doi":"10.1111/jocd.71088","DOIUrl":"https://doi.org/10.1111/jocd.71088","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Accurate prediction of the number of sessions required for laser tattoo removal is essential for effective treatment planning and patient counseling. The Kirby–Desai (KD) scale, developed for Q-switched nanosecond lasers, overestimates treatment sessions when applied to modern picosecond laser technology.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To develop and validate a novel predictive scoring system specifically calibrated for picosecond laser tattoo removal and to compare its predictive accuracy with the KD scale.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective cohort of 545 patients treated with picosecond laser tattoo removal between 2019 and 2024 was analyzed. Tattoo characteristics were evaluated using both the KD scale and the newly developed (PT) scale, which incorporates six parameters: tattoo type, pigment density, anatomical location, ink color, scarring, and layering. Multiple regression and machine learning models were trained separately on KD- and PTbased variables. Model performance was assessed using mean absolute error (MAE), root mean square error (RMSE), and coefficient of determination (<i>R</i>²) on an independent test set. Model interpretability was evaluated using SHapley Additive exPlanations (SHAP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>PT-based models consistently outperformed KD–based models. The PT Ridge regression model achieved the best predictive performance (MAE = 0.58, RMSE = 0.64, <i>R</i>² = 0.73), significantly improving accuracy compared with KD-based approaches (<i>p</i> &lt; 0.001). SHAP analysis identified tattoo type and pigment density as the most influential predictors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The PT scale provides a more accurate and clinically relevant prediction of treatment sessions for picosecond laser tattoo removal than the KD scale, offering a practical and reliable tool for contemporary clinical practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148616095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Preliminary Report of Real-World Clinical Experience With Cold-Crosslinked Hyaluronic Acid Fillers: A Roundtable and Case Series","authors":"Kristine Romine,&nbsp;Terrence Keaney,&nbsp;Jason D. Bloom,&nbsp;G. Jackie Yee,&nbsp;Heather Rogers,&nbsp;Ellen Gendler","doi":"10.1111/jocd.71018","DOIUrl":"https://doi.org/10.1111/jocd.71018","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Though data from clinical studies can inform real-world application of new hyaluronic acid (HA) injectables, the eventual role of a given product in clinical practice is difficult to predict. Here, a panel of expert injectors share their experience with cold-crosslinking process (Cold-X Technology) HA fillers Evolysse Form (EVL_F) and Evolysse Smooth (EVL_S; Symatese, Chaponost, France).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty-one expert dermatologists and facial plastic surgeons with an average of 24 years of experience (range 13–40 years) were provided with EVL_F and EVL_S to treat real-world patients in their practices. All participants completed a survey on product use and overall experience and six participants participated in a 2-h roundtable where case studies were discussed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>EVL_F was most often used in the cheeks (16/21), NLF (15/21), chin (13/21), and marionette lines (12/21), and EVL_S in the marionette lines (15/21), oral commissures (15/21), and lips (13/21), using a range of different injection techniques. Seventy-six percent (16/21) of participants indicated that they were likely or very likely to incorporate EVL_F and EVL_S into their regular filler portfolio.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Experience with EVL_S and EVL_F was positive: both are versatile, do not necessitate changes to existing workflows, and are able to achieve efficient outcomes in clinical practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 7","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148615382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors and Nomogram Model for Poor Prognosis in Atrophic Scar Patients Treated With Fractional Laser Therapy: The Role of Nursing Care in a Retrospective Cohort Study","authors":"Jingjing Li,&nbsp;Mengjie Liu,&nbsp;Ting Zhou,&nbsp;Chaohua Liu,&nbsp;Minli Yang","doi":"10.1111/jocd.70827","DOIUrl":"https://doi.org/10.1111/jocd.70827","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Accurate prognosis prediction following fractional laser therapy for atrophic scars remains challenging in clinical practice. Current models predominantly focus on clinical parameters while neglecting the synergistic effects of psychosocial factors and nursing interventions, limiting their predictive accuracy and clinical applicability.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This study aimed to develop and validate an integrative nomogram incorporating biological, clinical, and nursing-related variables to predict poor scar prognosis after fractional CO₂ laser therapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this retrospective cohort study, 180 patients receiving laser therapy (2020–2024) were randomly allocated into training (<i>n</i> = 125) and validation (<i>n</i> = 55) cohorts. Multivariate logistic regression with LASSO penalty was employed to analyze clinical parameters (age, skin type, ECCA severity), comorbidities, and psychosocial factors (emotional care status, negative emotions). A nomogram was constructed using R software and validated through ROC analysis, bootstrap resampling, and decision curve analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seven independent predictors were identified: advancing age (OR = 1.23/year, 95% CI: 1.11–1.38), combination skin type (OR = 12.46 vs. neutral), concurrent skin diseases (OR = 3.92), severe ECCA classification (OR = 12.72 vs. mild), laser energy (OR = 5.01 vs. high), the presence of negative emotions (OR = 10.98), and inadequate emotional care (protective OR = 0.12). The model demonstrated excellent discrimination (training AUC = 0.96, validation AUC = 0.93) and calibration accuracy (slope = 0.98, intercept = −0.03). Decision curve analysis confirmed clinical utility across 15%–35% risk thresholds.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This novel nomogram represents the first prognostic tool integrating biological susceptibility and nursing-mediated resilience, providing clinicians with a validated instrument for personalized risk stratification and optimized care pathway design. The model's high accuracy and generalizability support its implementation in both clinical practice and research settings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 7","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70827","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148467016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Laser-Induced Chrysiasis Treated With Pulsed Intense Light and Chemical Peels","authors":"Rosemarie Mazzuco,&nbsp;Juliano Adolfo Grock,&nbsp;Airá Novello Villar,&nbsp;Sarah Lyane Venzon,&nbsp;Analupe Webber","doi":"10.1111/jocd.71005","DOIUrl":"https://doi.org/10.1111/jocd.71005","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Gold salts (chrysotherapy) were widely used for the treatment of moderate to severe rheumatoid arthritis during the 1990s. Following administration, gold particles may deposit permanently in multiple tissues, including the skin. Exposure to ultraviolet radiation can induce a characteristic blue-gray pigmentation known as chrysiasis. More recently, short- and ultra-short-pulse lasers have also been implicated in triggering chrysiasis, although the underlying mechanism remains poorly understood.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe two cases of laser-induced chrysiasis occurring decades after chrysotherapy and to propose a simple treatment approach using intense pulsed light (IPL) and chemical peels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Two patients with a remote history of gold salt therapy for rheumatoid arthritis, discontinued more than 30 years earlier, developed facial blue-gray pigmentation following laser procedures. Clinical findings, treatment strategy, and outcomes were evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Both patients presented with laser-induced chrysiasis affecting sun-exposed facial areas. Treatment combining IPL sessions and chemical peels resulted in rapid and significant improvement in pigmentation, with good cosmetic outcomes and no major adverse effects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Laser-induced chrysiasis may occur even decades after gold salt administration. Dermatologists should routinely investigate prior chrysotherapy exposure, particularly in patients with a history of rheumatoid arthritis, before performing laser treatments. IPL combined with chemical peels may represent a safe and effective therapeutic option for managing this challenging condition.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"25 7","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.71005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148467017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}