{"title":"Insights From the Supreme Court Decisions: Undesirable Consequences After Minimally Invasive Cosmetic Interventions in Türkiye.","authors":"Mahmut Şerif Yıldırım, Sema Koç Yıldırım","doi":"10.1111/jocd.16588","DOIUrl":"10.1111/jocd.16588","url":null,"abstract":"<p><strong>Background: </strong>With the increasing demand for cosmetic procedures in recent years, the implementation of some of these procedures by unauthorized persons has led to undesirable results and subsequently to the creation of a large number of case files.</p><p><strong>Aims: </strong>In this study, it is aimed to retrospectively evaluate the decision texts of the Turkish Supreme Court regarding minimally invasive cosmetic dermatology procedures and to evaluate the reasons and results of the applications reaching the high court in these procedures.</p><p><strong>Methods: </strong>The Supreme Court's decisions in cases filed due to undesirable consequences caused by minimally invasive cosmetic interventions were scanned using the Supreme Court of Appeals' online database from 2013 to 2023.</p><p><strong>Results: </strong>The majority of the procedures addressed by the lawsuits are carried out in beauty salons; laser epilation is the procedure that is conducted most frequently, and burns are the most prevalent complication (87.8%, 85.7%, and 77.6%, respectively). As an adverse event, 94.7% (n = 36) of burns occurred in beauty centers. Thirteen (26.5%) of the cases in our analysis were carried out by an unauthorized person. When laser epilation and other procedures are considered as two separate categories, in applications due to adverse events of laser epilation, 28 (66.7%) cases were concluded in favor of the defendant.</p><p><strong>Conclusions: </strong>Complications, especially burns, that occur after laser epilation performed by unauthorized persons in beauty salons constitute a serious caseload, and there seems to be a need for better control mechanisms to reduce this burden.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16588"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beverage Consumption and Facial Skin Aging: Evidence From Mendelian Randomization Analysis: Comment From Liu et al.","authors":"Hainan Li, Ao He, Xian Zhao","doi":"10.1111/jocd.16597","DOIUrl":"10.1111/jocd.16597","url":null,"abstract":"","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16597"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genetic Causal Association Between Skin Microbiota and Biological Aging: Evidence From a Mendelian Randomization Analysis.","authors":"Yuan Li, Liwen Ma, Lipan Fan, Chuyan Wu, Dan Luo, Feng Jiang","doi":"10.1111/jocd.16762","DOIUrl":"10.1111/jocd.16762","url":null,"abstract":"<p><strong>Background: </strong>The skin microbiota, a complex community of microorganisms residing on the skin, plays a crucial role in maintaining skin health and overall homeostasis. Recent research has suggested that alterations in the composition and function of the skin microbiota may influence the aging process. However, the causal relationships between specific skin microbiota and biological aging remain unclear. Mendelian randomization (MR) analysis provides a powerful tool to explore these causal links by utilizing genetic variants as instrumental variables, thereby minimizing confounding factors and reverse causality that often complicate observational studies.</p><p><strong>Methods: </strong>We utilized a two-sample MR approach with population-based cross-sectional data from two German cohorts, KORA FF4 (n = 324) and PopGen (n = 273). In total, GWAS summary data from 1656 skin samples and datasets on accelerated biological age were analyzed to investigate the causal relationship between skin microbiota and accelerated biological aging. The primary analysis was performed using the inverse variance weighted (IVW) method with random effects and was further supported by MR-Egger regression, Cochran's Q test, and a range of sensitivity analyses.</p><p><strong>Results: </strong>The MR analysis revealed that for biological age acceleration (BioageAccel), the IVW analysis identified protective effects from certain skin microbiota, including Alphaproteobacteria_Dry (p = 0.046), Asv033_sebaceous (p = 0.043), Burkholderiales_Moist (p = 0.008), and Proteobacteria_Moist (p = 0.042). Similar protective effects were observed for Burkholderiales_Moist (p = 0.045) and Proteobacteria_Moist (p = 0.012) in the weighted median analysis. In contrast, Paracoccus_Moist (p = 0.013) and Proteobacteria_Sebaceous (p = 0.005) were associated with accelerated aging. When using PhenoAge acceleration as the outcome, the IVW analysis linked skin microbiota like Asv005_Dry (p = 0.026), ASV039_Dry (p = 0.003), Betaproteobacteria_Sebaceous (p = 0.038), and Chryseobacterium_Moist (p = 0.013) with accelerated aging. The weighted median analysis supported these findings and also identified protective effects from ASV011_Dry (p = 0.021), ASV023_Dry (p = 0.040), Bacteroidales_Dry (p = 0.022), Enhydrobacter_Moist (p = 0.038), Proteobacteria_Moist (p = 0.002), and Rothia_Moist (p = 0.038).</p><p><strong>Conclusions: </strong>This two-sample MR study reveals potential causal relationships between skin microbiota and aging. However, to confirm these findings, further randomized controlled trials (RCTs) are necessary.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16762"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful Treatment of Subungual Warts With Pulsed Dye Laser: Report of Four Cases.","authors":"Shuang Lyu, Zhenhua Yue, Huimin Zhang, Xi'an Fu, Hong Liu, Furen Zhang","doi":"10.1111/jocd.16756","DOIUrl":"10.1111/jocd.16756","url":null,"abstract":"","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16756"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomoki Akahane, Daisuke Watanabe, Eri Shimizu, Kosei Tanaka, Kazuhiro Kaizu
{"title":"Efficacy of Pseudo-Ceramide Absorption Into the Stratum Corneum and Effects on Transepidermal Water Loss and the Ceramide Profile: A Randomized Controlled Trial.","authors":"Tomoki Akahane, Daisuke Watanabe, Eri Shimizu, Kosei Tanaka, Kazuhiro Kaizu","doi":"10.1111/jocd.16655","DOIUrl":"10.1111/jocd.16655","url":null,"abstract":"<p><strong>Background: </strong>Changes in the level or profile of ceramides are associated with decreased stratum corneum (SC) barrier function. Topical application of a pseudo-ceramide (pCer)-containing moisturizer can improve barrier function. Additionally, pCer that absorbs into the SC may improve ceramide profiles.</p><p><strong>Aim: </strong>We investigated the relationship between pCer absorption into the SC and SC properties and determined the efficacy of a pCer-containing spray compared with that of a commercial spray without pCer.</p><p><strong>Patients/methods: </strong>Patients with self-perceived dry and sensitive skin and decreased barrier function (transepidermal water loss [TEWL] > 10 g/m<sup>2</sup>h) were randomized into two groups to topically apply a pCer-containing spray (test group; N = 33) or commercial spray without pCer (control group; N = 19) twice daily as a single-blind study. SC function and ceramide properties were investigated before and after 4 weeks of application.</p><p><strong>Results: </strong>In the test group, the ceramide (NP)/(NS) ratio proportionally increased with the pCer application level after 4 weeks of pCer-containing spray application. In the control group, there were no changes in SC function after topical application of the commercially available spray without pCer; however, the SC water content, TEWL, SC cell area, and scaling score improved in the test group. Furthermore, the changes in TEWL in the test group were significantly negatively correlated with the pCer application level.</p><p><strong>Conclusions: </strong>The efficacy of pCer-containing sprays for those who have sensitive skin with impaired barrier function was demonstrated. Furthermore, the improvement in SC barrier function induced by pCer may contribute to normalizing the SC ceramide profile.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16655"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Priscilla Huang, Olivia Supan, Cecilia L Pak, Rahul C Mehta, Elizabeth T Makino
{"title":"Efficacy and Tolerability of a Novel Cosmetic and Over-the-Counter Facial Acne Regimen Versus a Prescription Treatment.","authors":"Priscilla Huang, Olivia Supan, Cecilia L Pak, Rahul C Mehta, Elizabeth T Makino","doi":"10.1111/jocd.16568","DOIUrl":"10.1111/jocd.16568","url":null,"abstract":"<p><strong>Background: </strong>The SkinMedica Acne Treatment Platform (SM Regimen) was formulated to treat acne without overdrying the skin. We evaluated efficacy and tolerability of the SM Regimen (including a novel 1% salicylic acid Acne Clarifying Cleanser and 2% salicylic acid Acne Treatment Lotion) versus a prescription formulation (Rx Regimen; including adapalene 0.1%/benzoyl peroxide 2.5%) in a diverse population of adults with mild to moderate facial acne.</p><p><strong>Methods: </strong>This single-center, double-blind, randomized study enrolled adults (18-45 years) with Fitzpatrick skin types (FST) I-VI. SM Regimen or Rx Regimen was applied topically to the entire face for 12 weeks. Assessments were conducted at 24 and 48 h and 4, 8, and 12 weeks.</p><p><strong>Results: </strong>Subjects (SM Regimen, n = 31; Rx Regimen, n = 23) were primarily female (90.7%) with mean age of 28.6 years; 53.8% had FST IV-VI. Efficacy was comparable between regimens. The SM regimen resulted in significant improvements versus baseline in mean Investigator's Global Assessment of acne severity from 48 h through week 12 (p ≤ 0.001), as well as significant and sustained improvements from baseline in total acne lesion count, global postinflammatory hyperpigmentation/postinflammatory erythema, and oiliness. The SM Regimen was well tolerated at all time points, with mean scores below mild for all parameters; the Rx Regimen caused significantly more tightness/dry feeling at week 4 versus SM Regimen (p = 0.008). Subjects (> 96%) reported high satisfaction with the SM Regimen at all time points.</p><p><strong>Conclusions: </strong>The SM Regimen reduced acne severity and skin oiliness, evening out skin tone without overdrying or irritating the skin.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16568"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Short Snips: YouTube Shorts Recommendations for Hair Loss and Alopecia.","authors":"Michelle Ko, David Kim, Emily Newsom, Carolyn Goh","doi":"10.1111/jocd.16608","DOIUrl":"10.1111/jocd.16608","url":null,"abstract":"","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16608"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dario Bertossi, Radina Denkova, Anna Jen Shi Hoo, David Loh, Marshall Murdoch, Isaac Shturman Sirota, Fernando Urdiales-Gálvez, Marcel Vinícius de Aguiar Menezes, Carola de la Guardia
{"title":"Structural Aesthetic Treatment With the Hyaluronic Acid Filler VYC-25L: Global Expert Considerations for Safe and Effective Long-Term Outcomes.","authors":"Dario Bertossi, Radina Denkova, Anna Jen Shi Hoo, David Loh, Marshall Murdoch, Isaac Shturman Sirota, Fernando Urdiales-Gálvez, Marcel Vinícius de Aguiar Menezes, Carola de la Guardia","doi":"10.1111/jocd.16555","DOIUrl":"10.1111/jocd.16555","url":null,"abstract":"<p><strong>Background: </strong>VYC-25L is a robust, structural hyaluronic acid (HA) filler designed for facial volumizing, lifting, and contouring. It was first approved in 2019.</p><p><strong>Methods: </strong>A group of doctors with various specialties, who have used VYC-25L extensively since it first became available in their countries (3-5 years), share clinical experience and guidance on optimal use.</p><p><strong>Results: </strong>VYC-25L has a unique rheological and physicochemical profile that provides elevated lift capacity and enhanced projection, significant moldability immediately after injection, high levels of tissue integration, reversibility with hyaluronidase, and a long duration of clinical effects-typically lasting at least 24 months. The properties of VYC-25L have created new possibilities for nonsurgical facial medical aesthetics. However, as with any novel product, it is important that injectors recognize how best to use it for the benefit of patients. When first utilizing VYC-25L, it is advisable to start with the chin and jawline to gain familiarity with the gel characteristics before moving into other facial areas, and to consider splitting treatment over two or more sessions. Attention must also be given to injection volume, with less product typically required with VYC-25L compared to other fillers with similar indications. Key principles of good practice should be followed, including appropriate patient selection and pretreatment education, suitable choice of injection device and plane, aseptic technique, slow and careful administration method, and sufficient posttreatment follow-up.</p><p><strong>Conclusions: </strong>By adhering to these principles, VYC-25L can produce natural-looking and highly durable outcomes without substantial safety concerns.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16555"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142729319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subcision-The Art of Controlled Aggression.","authors":"Davin S Lim","doi":"10.1111/jocd.16746","DOIUrl":"https://doi.org/10.1111/jocd.16746","url":null,"abstract":"","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16746"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}