Journal of Cosmetic Dermatology最新文献

{"title":"Effectiveness and Safety of Micro-Plasma Radiofrequency Treatment Combined With Autologous Chyle Fat Grafting Treatment for Hypertrophic Scars: A Retrospective Study.","authors":"Peixuan Zhang, Haina Pei, Guiwen Zhou, Qiang Fu, Ruiqi Bai, Pianpian Lin, Qian Wu, Xiao Xu, Minliang Chen","doi":"10.1111/jocd.16728","DOIUrl":"10.1111/jocd.16728","url":null,"abstract":"<p><strong>Background: </strong>Hypertrophic scar (HS) is a fibroproliferative disorder resulting from abnormal healing of skin tissue after injury. Although various therapies are currently employed in clinical to treat HSs, there is no widely accepted standard therapy. Micro-plasma radiofrequency (MPR) and autologous chyle fat grafting are emerging treatments for this condition, and they have demonstrated promising therapeutic outcomes in clinical applications. The aim of this study is to investigate the effectiveness and safety of combining MPR with autologous chyle fat grafting for the treatment of HSs.</p><p><strong>Methods: </strong>We performed a retrospective study on patients diagnosed with HS in a single center between January 2020 and December 2023. According to the treatments, patients were divided into three groups, with 6 months follow-up. The single therapy group received MPR alone for two times. The combined therapy Group 1 first received the MPR treatment followed by the combined treatment. The combined therapy Group 2 first received the combined treatment and then received the MPR treatment. The effectiveness of treatment was evaluated using the Vancouver Scar Scale (VSS) and the Patient Scar Assessment Scale (PSAS). The Visual Analog Scale (VAS) was used to assess the patients' pain on the day of treatment and 1 day after treatment. Adverse events and complications were recorded to assess the safety of treatment.</p><p><strong>Results: </strong>A total of 73 patients diagnosed with HS were enrolled in this study, including 35 patients in the single therapy group, 18 patients in the combined therapy Group 1, and 20 patients in the combined therapy Group 2. After the treatments were completed, all three groups exhibited significant effectiveness. The two combined therapy groups scored lower after treatments in the VSS, which includes height, vascularity, pliability, and total scores, as well as in the PSAS, which includes color, stiffness, thickness, and total scores, compared to the single therapy group, with a statistically significant difference. Regarding pain response to treatment, there was no statistical difference in VAS among the three groups. No statistical difference in the overall incidence of adverse events was observed among the three groups, and no severe complications were recorded.</p><p><strong>Conclusions: </strong>This study revealed the combination of MPR and autologous chyle fat grafting showed superior effectiveness compared to MPR alone in treating HSs, without any observed increase in overall adverse event frequency. For patients diagnosed with HS, this combination therapy stands as a promising and effective clinical intervention.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16728"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11681299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation and Evaluation of the Effectiveness of an Anti-Wrinkle Cream Containing Equisetum arvense and Soybean Extracts.","authors":"Sara Nojomi, Fatemeh Soltanmohammadi, Hamideh Azimi Alamdari, Sanaz Hamedyazdan, Adel Mahmoudi Gharehbaba, Yousef Javadzadeh","doi":"10.1111/jocd.16734","DOIUrl":"10.1111/jocd.16734","url":null,"abstract":"<p><strong>Background: </strong>Skin aging is a multifaceted condition marked by the development of wrinkles, reduced suppleness, and uneven pigmentation. Both endogenous and exogenous factors contribute to skin aging. Studies have examined the possible anti-aging advantages of horsetail and soybean extracts, which are abundant in antioxidants.</p><p><strong>Methods: </strong>A study was conducted to develop and assess the stability of an anti-wrinkle cream combining horsetail and soybean extracts over a period of 6 months. This study was a pilot study that was prospective and noncomparative in nature. An investigation was performed to explore the efficiency of a treatment on wrinkles on the forehead. The study involved 15 volunteers between the ages of 35 and 55, and the modified Fitzpatrick wrinkle grading scale (FWS) method was used to assess the results. The participants were directed to administer cream to the forehead region for a duration of eight sequential weeks. Images were acquired at the initial stage and after 8 weeks of treatment. An independent investigator evaluated the improvement in the overall appearance of the forehead skin by comparing clinical images taken before and after the therapy.</p><p><strong>Results: </strong>The cream exhibited exceptional stability, showing no noteworthy alterations in pH, viscosity, or microbiological count. The clinical findings demonstrated a notable decrease in the average FWS score from 8.7 ± 1.3 to 6.1 ± 1.8 (p < 0.005) after the treatment. 93.4% of the individuals experienced a positive alteration in the appearance of their forehead wrinkles.</p><p><strong>Conclusion: </strong>The formulated cream presents a hopeful method to tackle skin aging issues, backed by its durability and effectiveness in diminishing wrinkles. Additional investigation is necessary to clarify the underlying mechanisms.</p><p><strong>Trial registration: </strong>IRCT20190917044799N1.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16734"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11681310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging Single Nucleotide Polymorphism Profiling for Precision Skin Care: How SNPs Shape Individual Responses in Cosmetic Dermatology.","authors":"Diala Haykal","doi":"10.1111/jocd.16750","DOIUrl":"10.1111/jocd.16750","url":null,"abstract":"<p><strong>Introduction: </strong>Single-nucleotide polymorphisms (SNPs) represent a significant genetic variation influencing individual responses to cosmetic dermatology treatments. SNP profiling offers a pathway to personalized skincare by enabling practitioners to predict patient outcomes, customize interventions, and mitigate risks.</p><p><strong>Background: </strong>The integration of genetic insights into dermatology has gained traction, with SNP analysis revealing predispositions in skin characteristics, such as collagen degradation, pigmentation, and inflammatory responses. Key SNPs, including MMP1, SOD2, TYR, and IL-6, are pivotal in determining skin health and treatment outcomes. Despite its promise, the adoption of SNP profiling in cosmetic dermatology is in its infancy, requiring further exploration of its practical applications.</p><p><strong>Results: </strong>SNPs significantly influence skin responses to aesthetic treatments, offering insights for personalized care. Variations in MMP1 correlate with collagen degradation, suggesting collagen-stimulating therapies, while SOD2 SNPs highlight the need for antioxidant support. TYR variations affect pigmentation risks in light-based treatments, and IL-6 SNPs reveal inflammatory predispositions, guiding anti-inflammatory protocols. AI integration enhances SNP profiling by improving prediction accuracy and treatment customization. Challenges remain, including standardization, ethical considerations, and cost-effectiveness. Combining genetic insights with epigenetics and leveraging AI technologies can amplify precision and safety in dermatologic care.</p><p><strong>Conclusion: </strong>SNP profiling marks a transformative step toward precision medicine in cosmetic dermatology, enabling tailored treatments that enhance efficacy and minimize adverse effects. Integrating AI-driven SNP analysis with epigenetic insights provides a comprehensive approach to patient care, fostering a new era of personalized skincare that respects genetic and environmental interactions. This paradigm shift holds the potential to redefine dermatologic practices, improving outcomes and patient satisfaction.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16750"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation and Evaluation of Complexed Ubiquinone (Coenzyme Q10) Antiaging Hyaluronic Acid-Vitamin C Serum for Skin Care.","authors":"Hawazin Arkan Yousif, Israa Al-Ani, Maha N Abu Hajleh, Sina Matalqah, Wael Abu Dayyih, Emad A Al-Dujaili","doi":"10.1111/jocd.16706","DOIUrl":"10.1111/jocd.16706","url":null,"abstract":"<p><strong>Background: </strong>Coenzyme Q10 (CoQ10) is widely recognized for its powerful antioxidant properties, sparking considerable interest in its application within skincare treatments. However, its inherently poor water solubility has posed a major challenge in formulating effective skincare products.</p><p><strong>Methods: </strong>This research aimed to develop and evaluate a water-soluble CoQ10 serum by forming a complex with hydroxypropyl β-cyclodextrin (HPβCD). The study focused on assessing its physicochemical properties, CoQ10 concentration, spread ability, viscosity, pH, physical stability, irritation potential, and diffusion performance. The complexation process was carried out using kneading and trituration techniques, with thorough characterization via validated analytical methods such as solubility tests, Fourier transform infrared spectroscopy (FTIR), and differential scanning calorimetry (DSC) analyses.</p><p><strong>Results: </strong>The CoQ10-HPβCD complex prepared using the trituration technique at a 2:1 ratio (CoQ10 to HPβCD) demonstrated superior water solubility, reaching 17.5 ± 1.8 mg mL^-1, the highest among the tested formulations. Moreover, this formulation achieved the greatest encapsulation efficiency, retaining 71% ± 3.8% of CoQ10. FTIR and DSC analyses confirmed the successful formation of the complex. The formulated serum exhibited shear-thinning behavior, an optimal pH of 4.3 ± 0.2 closely aligning with the skin's natural acidity for enhanced compatibility-along with excellent spreadability and stability. Diffusion tests revealed a significant enhancement in solubility when CoQ10 was complexed, effectively overcoming its solubility barrier. Irritation tests validated the serum's safety for topical use.</p><p><strong>Conclusion: </strong>This study successfully developed a CoQ10 serum that overcame its solubility limitation, demonstrating favorable properties for skincare application. With its strong physicochemical characteristics and biocompatibility, this formulation shows significant promise for broader incorporation into skincare products.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16706"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11683515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Rose Stem Cell-Derived Exosomes (RSCEs) in Skin Treatment: From Healing to Hyperpigmentation Management: Case Series and Review.","authors":"Lidia Majewska, Karolina Dorosz, Jacek Kijowski","doi":"10.1111/jocd.16776","DOIUrl":"https://doi.org/10.1111/jocd.16776","url":null,"abstract":"<p><strong>Objective: </strong>To present and analyze eight clinical cases illustrating the use of rose stem cell-derived exosomes (RSCEs) in treating various dermatological conditions and to review current literature on plant-derived exosomes in medicine and dermatology.</p><p><strong>Background: </strong>RSCEs possess low cytotoxicity, high biocompatibility, and effective cellular uptake, making them promising agents for dermatological therapies. A literature review included in the introduction and discussion covers the broader role of plant-derived exosomes, highlighting their therapeutic potential in skin treatment.</p><p><strong>Methods: </strong>A case-by-case analysis was conducted on eight patients with conditions including atopic dermatitis (AD), hyperpigmentation, scarring, wounds, melasma, and antiaging concerns. Each case provided insights into RSCEs' efficacy, with a focus on their antioxidant and anti-inflammatory properties, as well as specific learning points derived from clinical observations.</p><p><strong>Results: </strong>The cases demonstrated RSCEs' multifaceted therapeutic effects across different skin conditions, supporting their role in enhancing skin regeneration, wound healing, and reducing hyperpigmentation and scarring. The literature review underscored RSCEs' unique bioactivity, suggesting mechanisms for their observed effects, including anti-inflammatory and rejuvenating properties, which contributed to favorable clinical outcomes.</p><p><strong>Conclusion: </strong>RSCEs show potential as a valuable treatment in dermatology, as evidenced by the positive results across multiple skin conditions and their alignment with existing literature on plant-derived exosomes. This case series emphasizes the need for further randomized and controlled clinical trials to confirm these preliminary findings and expand RSCEs' clinical application in dermatology.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16776"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11736088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periprocedural Skincare for Nonenergy and Nonablative Energy-Based Aesthetic Procedures in Patients With Skin of Color.","authors":"Andrew F Alexis, Anneke Andriessen, Renée A Beach, Valeria Barreto Campos, Lisa R Ginn, Rodrigo Gutiérrez Bravo, Levashni Naidoo, Monica Li","doi":"10.1111/jocd.16712","DOIUrl":"https://doi.org/10.1111/jocd.16712","url":null,"abstract":"<p><strong>Background: </strong>Anti-aging facial procedures with nonenergy and nonablative energy devices are increasingly popular among patients with skin of color (SOC). Algorithms have addressed the measures to reduce the side effects related to aesthetic procedures, but few focus on SOC patients and periprocedural integrating skincare.</p><p><strong>Methods: </strong>Eight dermatologists from Brazil, Canada, South Africa, Mexico, and the USA participated in a meeting and an online follow-up to develop an algorithm for periprocedural skincare for nonenergy and nonablative energy-based facial aesthetic procedures in patients with SOC. A Delphi method was used to develop this algorithm and integrate information from the literature with panels' clinical experience and opinion, resulting in the current algorithm.</p><p><strong>Results: </strong>The algorithm has five sections, starting with a medical history and skin examination, followed by pretreatment measures beginning 2-4 weeks before the procedure, then measures on the day of the procedure, aftercare 1-7 days after the procedure, and follow-up care 1-4 weeks after the procedure and ongoing.</p><p><strong>Conclusions: </strong>This algorithm provides guidelines for treatment optimization of non-energy, non-ablative energy-based devices for SOC patients. It also provides physicians with skincare recommendations pre-, peri-, and post-aesthetic procedures.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16712"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11744056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intradermal Incobotulinum Toxin A for Postbreast Cancer Treatment Asymmetry: A Literature Review and Case Report.","authors":"Alejandra Bugallo, Luis Alberto Parra, Andreina Martinez Amado, Victoria De la Fuente, Evalicia Murúa, Eliana Garcés, Andrea Marcela Parra","doi":"10.1111/jocd.16754","DOIUrl":"10.1111/jocd.16754","url":null,"abstract":"<p><strong>Background: </strong>Botulinum toxin (BTX) is globally the most common aesthetic procedure. Its usage has expanded beyond facial treatments to therapeutic areas, including managing scars and postsurgical deformities. Breast cancer survivors often face significant deformities and asymmetry during recovery.</p><p><strong>Objectives: </strong>This study systematically reviewed literature from the past 4 years on botulinum toxin applications in breast cancer survivors and presented a case report of a patient treated with Incobotulinum toxin (IncoBonTA; Xeomin, Merz Pharmaceuticals GmbH, Frankfurt, Germany) for left breast deformity postchemotherapy and radiotherapy.</p><p><strong>Methods: </strong>Following PRISMA guidelines, a systematic search was conducted on PubMed and Scopus using keywords: \"botulinum toxin,\" \"breast cancer,\" and \"breast asymmetry,\" identifying relevant literature from 2020 to 2024. Five full-text articles were included. Additionally, a 2024 case report of a patient with significant breast asymmetry postsurgery and radiotherapy was published.</p><p><strong>Results: </strong>The literature review indicated botulinum toxin's primary uses in breast cancer include pain management, upper limb impairment, postsurgical scars, and capsular contracture. Although some benefits were reported, further research is needed. In the case report, the patient was treated in one session with IncoBonTA at two different dilutions based on contracture severity without complications.</p><p><strong>Conclusion: </strong>The review showed promising advances in using botulinum toxin for deformities secondary to oncological treatment in breast cancer patients. The therapy was administered to a 53-year-old patient, resulting in significant aesthetic improvement, especially at the nipple and areola, suggesting that it was a viable option for these patients.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":"e16754"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI in Aesthetic/Cosmetic Dermatology: Current and Future.","authors":"Sukruthi Thunga, Marius Khan, Soo Ick Cho, Jung Im Na, Jane Yoo","doi":"10.1111/jocd.16640","DOIUrl":"10.1111/jocd.16640","url":null,"abstract":"<p><strong>Background: </strong>Recent advancements in artificial intelligence (AI) have significantly impacted dermatology, particularly in diagnosing skin diseases. However, aesthetic dermatology faces unique challenges due to subjective evaluations and the lack of standardized assessment methods.</p><p><strong>Aims: </strong>This review aims to explore the current state of AI in dermatology, evaluate its application in diagnosing skin conditions, and discuss the limitations of traditional evaluation methods in aesthetic dermatology. Additionally, the review proposes strategies for future integration of AI to address existing challenges.</p><p><strong>Methods: </strong>A comprehensive review of AI applications in dermatology was conducted, in both diagnostic and aesthetic fields. Traditional methods such as subjective surveys and hardware devices were analyzed and compared with emerging AI technologies. The limitations of current AI models were evaluated, and the need for standardized evaluation methods and diverse datasets was identified.</p><p><strong>Results: </strong>AI has shown great potential in diagnosing skin diseases, particularly skin cancer. However, in aesthetic dermatology, traditional methods remain subjective and lack standardization, therefore limiting their effectiveness. Emerging AI applications in this field show promise, but they have significant limitations due to biased datasets and inconsistent evaluation methods.</p><p><strong>Conclusions: </strong>To develop the potential of AI in aesthetic dermatology, it is crucial to create standardized evaluation methods, collect diverse datasets reflecting various ethnicities and ages, and educate practitioners on AI's utility and limitations. Addressing these challenges will improve diagnostic accuracy, better patient outcomes, and help integrate AI effectively into clinical practice.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16640"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination Therapy With CGF and Microneedling-Assisted Compound Betamethasone for Resistant Alopecia Areata: A Pilot Study.","authors":"Lingling Jia, Changjiang Zhao, Hongyi Zhang, Hua Jiang, Jiachao Xiong, Yufei Li","doi":"10.1111/jocd.16591","DOIUrl":"10.1111/jocd.16591","url":null,"abstract":"<p><strong>Background: </strong>Alopecia areata (AA), an autoimmune disorder characterized by hair loss, can be particularly difficult to manage when patients do not respond to standard therapeutic approaches such as topical or injectable corticosteroids, contact immunotherapy, and systemic treatments. In instances where these conventional therapies prove ineffective, alternative or adjunctive treatments are sought. Concentrated growth factor (CGF) and microneedling (MN)-assisted drug delivery are promising methods for the treatment of different dermatological diseases.</p><p><strong>Objective: </strong>This study aimed to assess the practical benefits and the safety aspects of utilizing a dual treatment approach involving CGF and MN-assisted compound betamethasone for patients suffering from resistant AA that are unresponsive to conventional medical interventions.</p><p><strong>Material and methods: </strong>This retrospective study was based on evaluations of seven patients with refractory AA treated with CGF and MN-assisted compound betamethasone from July 2021 to December 2023. The efficacy of treatment was assessed by extents of hair regrowth percentages of involved areas.</p><p><strong>Results: </strong>Among the seven enrolled patients with refractory AA, a notable outcome was observed where one patient (14.3%) achieved a regrowth of hair by over 50%, while six patients (85.7%) exhibited complete recovery without any systemic or local adverse effects. Furthermore, the difference in SALT scores between baseline, and the final visit for all patients was found to be statistically significant, substantiating the therapeutic efficacy of the intervention employed.</p><p><strong>Conclusion: </strong>The present study demonstrated that the synergistic application of CGF in conjunction with MN-assisted compound betamethasone may constitute a promising and well-tolerated therapeutic modality for refractory AA, offering a potentially efficacious and safe treatment alternative.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16591"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Effect of PDO Facelift Threads on Facial Skin Tissues: An Ultrasonographic Analysis\".","authors":"","doi":"10.1111/jocd.16596","DOIUrl":"10.1111/jocd.16596","url":null,"abstract":"","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":"e16596"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}