Journal of Cosmetic Dermatology最新文献

{"title":"A Cohort Clinical Study on the Efficacy of Topical Salicylic Acid/Piroctone Olamine Dandruff Pre-Gel and Cleanser in Improving Symptoms of Moderate to Severe Seborrheic Dermatitis of the Scalp","authors":"Ling Ge,&nbsp;Zhiqing Liu,&nbsp;Shanhua Xu,&nbsp;Chuying Li,&nbsp;Meitong Jin,&nbsp;Yinli Luo,&nbsp;Yanli Kong,&nbsp;Jingbi Meng,&nbsp;Ge Zheng,&nbsp;Junzhi Gao,&nbsp;Ping Wang,&nbsp;Wei Bai,&nbsp;Heya Na,&nbsp;Xianchun Zhou,&nbsp;Zhehu Jin,&nbsp;Longquan Pi","doi":"10.1111/jocd.16742","DOIUrl":"10.1111/jocd.16742","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Scalp seborrheic dermatitis (SD) is a chronic, recurrent inflammatory skin condition associated with scalp sebum secretion and dysbiosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>The aim of this study is to evaluate the efficacy and safety of a topical salicylic acid/piroctone olamine/zinc salt of L-pyrrolidone carboxylate (Zinc PCA) scalp pre-application gel in combination with a salicylic acid/piroctone olamine/antimicrobial peptide cleansing lotion for the treatment of moderate to severe scalp SD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients/Methods</h3>\u0000 \u0000 <p>In this prospective cohort study, 20 patients with moderate to severe scalp SD were treated with a combination of the scalp pre-application gel and cleansing lotion for 4 weeks (one tube of the pre-application gel per week and the cleansing lotion used every 1–3 days depending on the frequency of hair washing). This was followed by maintenance treatment with the cleansing lotion for 12 weeks. Efficacy was assessed through clinical and trichoscopic examinations, measuring the severity of dandruff, itching, erythema, and greasiness using a 4-point scale.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>This cohort study included a total of 20 patients with moderate to severe scalp SD. By the 4th week, the average dandruff score had significantly decreased from a baseline of 2.45 to 1.10 (<i>p</i> &lt; 0.01). The average itchiness score reduced from 2.35 to 1.10 (<i>p</i> &lt; 0.01), the erythema score dropped from 1.55 to 1.10 (<i>p</i> &lt; 0.05), and the greasiness score decreased from 2.60 to 1.40 (<i>p</i> &lt; 0.01). After 16 weeks, 12 patients with severe SD improved to mild SD, and six patients with moderate SD also improved to mild. During the treatment, two patients experienced a recurrence of dandruff, which subsequently resolved. The overall clinical improvement was 80%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our study results indicate that the combination treatment of the scalp pre-application gel and cleansing lotion is highly effective and safe for treating SD. The subsequent use of the cleansing lotion effectively maintains the benefits of the combined treatment. Trichoscopic examination provides accurate and reliable quantifiable data, aiding in the monitoring of treatment progress.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exosomes for Aesthetic Dermatology: A Comprehensive Literature Review and Update","authors":"Milaan Shah,&nbsp;Victoria Dukharan,&nbsp;Luke Broughton,&nbsp;Carol Stegura,&nbsp;Nina Schur,&nbsp;Luna Samman,&nbsp;Todd Schlesinger","doi":"10.1111/jocd.16766","DOIUrl":"10.1111/jocd.16766","url":null,"abstract":"<p>January 30, 2025: This article published prematurely in error. The article will republish shortly.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Series of a Novel Approach in the Treatment of Rosacea: Use of Botulinum Toxin and Intense Pulsed Light for the Treatment of Erythematotelangiectatic Rosacea","authors":"Cesar Gonzalez Ardila,&nbsp;Laura A. Colorado Franco,&nbsp;Manuel Franco,&nbsp;Andrea Galeano,&nbsp;Angie Julieth Holguin Molina,&nbsp;Julio R. Amador,&nbsp;Marco Rocha","doi":"10.1111/jocd.16774","DOIUrl":"10.1111/jocd.16774","url":null,"abstract":"&lt;p&gt;Rosacea is a chronic inflammatory skin disorder, prevalent in individuals with light skin, most of the times difficult to treat with conventional treatments [&lt;span&gt;1&lt;/span&gt;]. Although both Botulinum neurotoxin Type A (BoNT/A) and Intense Pulsed Light (IPL) separately have proven to be safe and effective alternatives, studies have shown that the combination of therapies may lead to better treatment outcomes [&lt;span&gt;2&lt;/span&gt;]. In our study, we found an improvement in erythematotelangiectatic rosacea using the combination of BoNT/A and IPL.&lt;/p&gt;&lt;p&gt;Intense Pulsed Light (IPL) is a well-established light-based therapy for various skin diseases, particularly in alleviating erythematous telangiectasia, papules, and pustules. IPL operates using a broad spectrum of light, with wavelengths ranging from 500 to 1200 nm modifiable through various filters [&lt;span&gt;3&lt;/span&gt;]. Its effects include the following: mast cell membrane stabilization, inhibiting their degranulation, and the release of cytokines and mediators (histamine, tryptase, MMP-9, and LL-37), ultimately achieving a therapeutic effect [&lt;span&gt;3&lt;/span&gt;]. Despite its effectiveness, it is commonly noted that monotherapy does not achieve long-lasting results in this condition. In contrast, patients who receive combination treatments, including (BoNT/A), experience improvements that persist for a much longer duration [&lt;span&gt;4&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Botulinum neurotoxin (BoNT) blocks the release of acetylcholine and modulates other neuropeptides, such as vascular endothelial growth factor, substance P, and calcitonin gene-related peptide, which influences vasodilation and inhibits the release of cathelicidin and inflammatory mediators promoting an anti-inflammatory effect that alleviates facial redness. Inhibits mast cell degranulation, stimulating an anti-inflammatory effect [&lt;span&gt;5&lt;/span&gt;]. The effect of BoNT/A injection is generally gradual after 3 days reaching efficacy peak 2 weeks after injection. If improvement is not satisfactory at the 2-week follow-up, complementary therapy can be administered. To avoid the thermal effect that accelerates the diffusion of local BoNT/A, the skin should be cooled after photoelectric treatment. Alternatively, photoelectric treatment can be administered at least 2 weeks after injection. Patients with severe lesions should be considered systemic medication to quickly control inflammation [&lt;span&gt;6&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Therefore, considering the previously mentioned mechanisms of action, combining these two therapies could result in a potential synergistic effect, likely leading to better outcomes for our patients.&lt;/p&gt;&lt;p&gt;We reviewed the medical records of 14 patients diagnosed with erythematotelangiectatic rosacea, all over 18 years old. As exclusion criteria, they could not have previously received topical therapy, injectables, or IPL treatment for their initial condition.&lt;/p&gt;&lt;p&gt;They received treatment with one session of IPL at 560 nm and 14 joules followed by injections of BoNT/A","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Complementary and Alternative Medicine Use for the Management of Acne Vulgaris Among University Students: Forms, Trends, and Information Sources","authors":"Sari Taha,&nbsp;Manal Taha,&nbsp;Sa'ed H. Zyoud","doi":"10.1111/jocd.16775","DOIUrl":"10.1111/jocd.16775","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Acne vulgaris is a common skin disease that has physical and psychological impacts. Patients diagnosed with acne often use complementary and alternative medicine, despite the insufficient evidence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This cross-sectional study sought to identify the types, trends in and reasons for utilizing complementary and alternative medicine for acne among university students.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients/Methods</h3>\u0000 \u0000 <p>The study was conducted among health sciences students from March to June, 2023, using clinical examination and a questionnaire. All participants were assessed for a diagnosis of acne.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The final sample size consisted of 367 participants, of whom 68.9% were females and 31.1% were males. The study revealed a high prevalence of acne (74.4%). Among those with acne, 59.7% reported using complementary and alternative medicine, with the biological forms being most frequent at 90.2%. The reasons commonly stated for using complementary and alternative medicine were lack of severity (48.5%) and the potential for internet-based self-treatment (33.1%). The main sources of information were the internet (44.8%) and social media (41.1%). Age, gender, and the occurrence of acne on the chin were associated with complementary and alternative medicine use (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The use of complementary and alternative medicine for treating acne is widespread, with a tendency toward biological forms. Healthcare practitioners should be familiar with the patterns of complementary and alternative medicine use for the treatment of acne to better meet patient needs and concerns. Policymaking can leverage the role of online resources in addressing the use of unconventional treatment modalities.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16775","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facial Thread Lifting Complications","authors":"Kyu-Ho Yi,&nbsp;Soo Yeon Park","doi":"10.1111/jocd.16745","DOIUrl":"10.1111/jocd.16745","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Thread lifting is a minimally invasive technique for addressing facial aging and skin laxity. Despite its popularity, it carries risks of complications ranging from minor bruising to severe structural injuries. Comprehensive understanding of these complications is vital for optimizing outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To analyze the complications associated with facial thread lifting, provide insights into their underlying mechanisms, and propose effective management strategies to minimize risks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients/Methods</h3>\u0000 \u0000 <p>A comprehensive review of complications from thread lifting was conducted, focusing on patient outcomes and procedural challenges. Data from clinical studies, case reports, and expert recommendations were analyzed to identify common and severe complications. Advanced techniques, such as ultrasound-guided procedures, were evaluated for their efficacy in preventing complications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Common complications included bruising, pain, swelling, bleeding, and dimpling, often arising from improper technique or anatomical factors. Severe issues such as infection, granuloma, thread migration, nerve damage, and parotid gland injuries were less frequent but posed significant challenges. Management strategies included massage, saline or filler injections, botulinum toxin, and surgical interventions for persistent or severe cases. Ultrasound-guided techniques demonstrated efficacy in reducing risks, particularly for glandular and vascular injuries.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>While thread lifting offers a promising alternative to surgical facelifts, its success depends on precise technique, anatomical knowledge, and effective complication management. Preventive measures, including preoperative planning, proper thread placement, and patient-specific customization, are crucial. Future advancements in imaging technologies and thread materials will likely enhance safety and efficacy, ensuring better patient satisfaction and outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16745","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Tolerability and Improved Outcomes in Acne Management: A Real-World Study of Dermocosmetic Adjunctive Therapy","authors":"Dong Hye Suh,&nbsp;Tae-Eun Kim,&nbsp;Sang Jun Lee,&nbsp;Su Jin Jeong,&nbsp;Eunsun Baek,&nbsp;Min Kyung Shin","doi":"10.1111/jocd.16772","DOIUrl":"10.1111/jocd.16772","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Topical retinoids, while renowned for their efficacy in treating acne vulgaris, are often hampered by inter-individual variability in tolerability. This challenge, primarily driven by side effects like erythema, scaling, and dryness, significantly impacts patient adherence and, ultimately, treatment outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This prospective, multi-center, observational study investigated the novel role of a specific dermocosmetic regimen as adjunctive therapy, focusing on its ability to mitigate retinoid-induced side effects and enhance the overall tolerability of acne treatment regimens in a Korean population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and Methods</h3>\u0000 \u0000 <p>We enrolled 304 patients receiving conventional acne therapies and integrated a standardized dermocosmetic regimen (foaming facial wash and moisturizer) for 12 weeks. Our primary endpoint assessed changes in skin sensitivity scores in both retinoid and non-retinoid users. We incorporated a patient-reported outcome measure evaluating acne's impact on quality of life across different facial areas as a secondary endpoint.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Our results revealed a significant improvement in skin sensitivity across both patient groups, effectively mitigating the anticipated heightened sensitivity in retinoid users. This finding suggests that dermocosmetics may hold the key to unlocking consistent, age-independent tolerance to retinoid therapy. Furthermore, we observed a compelling correlation between improvements in cheek acne and enhanced quality of life, highlighting the profound psychological impact of this specific facial area.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study pioneers a new understanding of holistic acne management, emphasizing the synergistic potential of dermocosmetics in enhancing treatment adherence, improving long-term outcomes, and ultimately transforming patients' lives.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11701793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in Noninvasive Imaging: Optical Coherence Tomography for Evaluating Therapeutic Efficacy in Vitiligo","authors":"Isabella J. Tan,&nbsp;Sydney M. Wolfe,&nbsp;Bernard A. Cohen","doi":"10.1111/jocd.16771","DOIUrl":"10.1111/jocd.16771","url":null,"abstract":"&lt;p&gt;Pigmentary disorders, particularly vitiligo, present significant challenges in dermatological treatment. Accurate monitoring of therapeutic efficacy is essential for optimizing treatment strategies. Noninvasive imaging offers a promising solution for real-time evaluation of skin changes, enabling clinicians to assess treatment outcomes while limiting invasive procedures. This manuscript analyzes the application of noninvasive imaging modalities, specifically optical coherence tomography (OCT), in assessing therapeutic responses in patients with vitiligo.&lt;/p&gt;&lt;p&gt;OCT integrates ultrasonography and optical interferometry to image skin horizontally and vertically up to 1–2 mm deep, capable of generating 3D images, particularly beneficial for deeper basal cell carcinoma subtypes and monitoring treatment responses while limiting additional biopsies, such as verifying clear margins and assessing therapeutic efficacy at the cellular level [&lt;span&gt;1, 2&lt;/span&gt;]. OCT is emerging as a practical, noninvasive tool for evaluating skin characteristics and tracking surgical treatment responses in patients with pigmentary disorders, such as vitiligo. Vitiligo is characterized by autoimmune-mediated loss of melanocytes and impaired melanin synthesis. OCT imaging can visualize skin changes by revealing decreased or absent scattering contrast between the stratum basale and dermal papillae. Recent studies demonstrate OCT's efficacy in assessing repigmentation post-skin grafting, detecting signs as early as Day 30 [&lt;span&gt;1&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;In comparison, techniques such as reflectance confocal microscopy (RCM) quantify vitiligo treatment response at a cellular level, capturing melanocyte migration across submillimeter scales [&lt;span&gt;3&lt;/span&gt;]. RCM visualizes cellular features in the epidermis, dermal–epidermal junction, and papillary dermis at near-histological resolution, using differential refractive indices to capture grayscale images up to 300 μm deep horizontally. This allows for enhanced diagnostic accuracy for melanocytic and non-melanocytic skin cancers, aiding in the diagnosis of inflammatory and infectious skin disorders [&lt;span&gt;3&lt;/span&gt;]. The VivaScope 1500 RCM device, with its high lateral resolution (~1 μm), limited imaging depth (~200–250 μm), and mosaic field of view (~8 × 8 mm), excels in detailed visualization of epidermal and dermo-epidermal structures, such as melanocytes and keratinocytes, making it particularly effective for assessing cellular-level repigmentation in vitiligo [&lt;span&gt;4&lt;/span&gt;]. In contrast, ultrahigh-resolution OCT, with a lower lateral resolution (~5–15 μm) but greater imaging depth (~1–2 mm) and comparable field of view (~8 × 8 mm), is better suited for efficiently monitoring structural changes in dermal papillae and larger-scale tissue alterations post-treatment (Table 1) [&lt;span&gt;1, 4&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Case studies using OCT for real-time monitoring of epidermal and dermal changes in vitiligo show promising results. One study investigat","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16771","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Nutrition Habits, BMI, Anxiety, and Seborrheic Dermatitis","authors":"Tayfun Batan,&nbsp;Ersoy Acer,&nbsp;Hilal Kaya Erdoğan,&nbsp;Esra Ağaoğlu,&nbsp;Muzaffer Bilgin,&nbsp;Zeynep Nurhan Saraçoğlu","doi":"10.1111/jocd.16737","DOIUrl":"10.1111/jocd.16737","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Seborrheic dermatitis (SD) is a chronic, inflammatory disease characterized by unknown etiopathogenesis. It affects skin areas rich in sebaceous glands. There are strong data on the relationship between nutrition habits, body mass index (BMI), psychoemotional status, and sebaceous gland diseases such as acne, rosacea, and androgenetic alopecia. However, there are very little data on SD, nutrition habits, BMI, and psychoemotional status.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>We aimed to evaluate the nutrition habits, BMI, and psychoemotional status in patients with SD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>One hundred patients with SD and 110 healthy controls aged 18–65 years were included. Adolescents Food Habits Checklist (AFHC), a questionnaire form consisting information about nutrition habits and Depression Anxiety Stress Scale-21 (DASS-21) were completed by the participants, and BMI was calculated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Severity of SD was positively correlated with BMI (<i>p</i> = 0.018). Patients with SD consumed more bread and less fruits–vegetables (<i>p</i> = 0.001, <i>p</i> = 0.006). Margarine, animal fat, and sugar consumption was higher in patients with moderate to severe SD (<i>p</i> = 0.008, <i>p</i> = 0.050). AFHC score was lower in patients with SD (<i>p</i> = 0.009). DASS-21 anxiety subscale and DASS-21 total scores were higher in the moderate to severe SD group (<i>p</i> = 0.035, <i>p</i> = 0.049).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Nutrition habits, higher BMI, and psychoemotional status may play a critical role in the etiopathogenesis of SD. Healthy nutrition habits and psychoemotional status may prevent the occurrence and exacerbation of SD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16737","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subcision—The Art of Controlled Aggression","authors":"Davin S. Lim","doi":"10.1111/jocd.16746","DOIUrl":"10.1111/jocd.16746","url":null,"abstract":"&lt;p&gt;We recently published a manuscript entitled “Complications of Subcision for Acne Scarring: Experience From Clinical Practice and Review of the Literature.” This article describes the various methodologies and instrumentations employed in subcision including the use of hypodermic needles, Nokor needles, cannulas, blunt blades, cataract blades, throught to repurposed dove tail Toledo cannulas and novel sharp-edged instruments such as the Taylor Liberator.&lt;/p&gt;&lt;p&gt;Different techniques have been described in the literature, ranging from the conservative localized undermining of focal areas, triangulation using longer instruments, and modification of hypodermic needles, through to aggressive field undermining in conjunction with energy devices. There are limited studies on the efficacy and side effects of different techniques due to the polymorphic nature of acne scarring in addition to a lack of standardized execution of the procedure itself. Most studies are multimodality treatments that reflect the variation of scar signatures seen in acne scar patients [&lt;span&gt;1&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Whilst some authors propose restricting the length of instrumentation to minimize collateral damage to retaining ligaments, others recommend employing longer flexible instruments alongside a more conservative approach to mitigate side effects at entry points. Despite initial studies showing positive outcomes with sharp needle instruments, recent research indicates that longer and broader instruments, rather than hypodermic needles, yield better results whilst minimizing operating times [&lt;span&gt;2&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;The plane of subcision has been largely agreed upon, namely the hypodermis; however, there is no consensus regarding the extent of undermining of the scar field. With “point subcision” using hypodermic needles, scars are released within a short distance of the chosen instrumentation. In comparison, longer instruments with wide dissecting heads (Taylor Liberators, blunt dissectors, and Toledo cannula) are more efficient at transection of scar tissue, with the drawback of collateral damage to normal tissue between scar areas. Over the past few years, there has been a trend to employ these described instruments as they require significantly less treatment time coupled with superior outcomes [&lt;span&gt;2-4&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Side effects such as hematomas, fibroplasia, post-inflammatory hyperpigmentation, entry site scarring, and paresthesia have been documented in the literature [&lt;span&gt;5&lt;/span&gt;], however In the past 2 years, I have observed two complications referred from other clinics that have been infrequently reported. Although not solely linked to a single instrument, these issues are more frequently associated with the use of a broad-based W-tip tool known as the Taylor Liberator. Most frequently, these side effects have occurred after a single aggressive treatment session.&lt;/p&gt;&lt;p&gt;Firstly, there is the phenomenon of persistent facial swelling lasting (defined by duration grea","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16746","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of a Nutraceutical Supplement With Standardized Botanicals in Males With Thinning Hair","authors":"Neal Bhatia,&nbsp;Glynis Ablon,&nbsp;Patricia K. Farris,&nbsp;Adina Hazan,&nbsp;Isabelle Raymond","doi":"10.1111/jocd.16778","DOIUrl":"10.1111/jocd.16778","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Hair thinning in men is a prevalent issue for which treatment oftentimes consists of a multi-modal approach. Targeting key root causes of hair thinning, such as hormones, stress, and metabolism through vitamins, minerals, and botanicals, has been shown to be effective in improving hair growth and quality in women. This approach could also be effective in improving hair growth and quality in men with thinning hair.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This study investigates the safety and efficacy of a nutraceutical in improving hair growth and quality in men with thinning hair.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This was a 6-month multi-center, double-blind, randomized, placebo-controlled trial. Men aged 21–61 years old with confirmed hair thinning were included. Subjects were randomized to receive the oral supplement or placebo. The study end points included changes in blinded Global Investigator Ratings for hair growth and quality, the Men's Hair Growth Questionnaire (MHGQ), and changes in the Arizona Sexual Experience Scale (ASEX) in the active group compared to baseline and placebo.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Daily intake of the nutraceutical resulted in significantly more subjects in the active group compared to the placebo rated as improved for hair growth and quality in the blinded investigator global assessments. Overall changes and responses to the MHGQ also corroborated blinded investigator ratings. There were no trends in either treatment group for changes in sexual function on the ASEX questionnaire, and the supplement was well tolerated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Ingestion of a nutraceutical targeting key root causes of male hair thinning significantly improves hair growth and quality in men with no changes in sexual function.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 1","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11701407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}