Journal of Cosmetic Dermatology最新文献

{"title":"Efficacy and Skin Acceptability of a Cosmetic Cream for Nasolabial Dryness and Irritation","authors":"Constance Prime,&nbsp;William Hooper,&nbsp;Yosra Ghrib Ben Sassi,&nbsp;Nejib Doss,&nbsp;Oliver Chen","doi":"10.1111/jocd.70107","DOIUrl":"https://doi.org/10.1111/jocd.70107","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Rhinorrhea is a widespread condition related to common upper respiratory insults such as influenza and rhinitis, often accompanied by frequent nose cleansing resulting in skin irritation. This study evaluated the cutaneous acceptability and nourishing, soothing, protecting, and moisturizing effects of Sterimar Soothing Nose Cream on the skin around the nose in healthy adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted an exploratory single-arm clinical trial in 33 adults (mean age 46 years) who blow their nose often (&gt; 5 times/day) due to a cold or allergies and have sensitive, irritated/dry nose. Participants applied the cream topically on their noses twice daily for 14 days. Cutaneous acceptability and efficacy measures were assessed by participants and by the study dermatologist before, during, and after 14 days. Skin imaging analysis via the Visia camera system and skin hydration via Corneometer were also assessed. Participants also completed a questionnaire about overall product performance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The dermatologist noted reduced (<i>p</i> &lt; 0.001) redness, swelling, dryness, roughness, and itchiness, with improved (<i>p</i> &lt; 0.001) hydration, softness, and flexibility after 7 and 14 days. Participants reported less (<i>p</i> &lt; 0.05) dryness, redness, and discomfort, with 97% rating the cream's soothing effect as moderate to strong. The cream also increased (<i>p</i> &lt; 0.0001) skin hydration by 14%, measured by Corneometer 30 min postapplication. No worsening of symptoms or adverse effects was reported. All participants found the cream pleasant, with most intending to purchase and continue use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The results indicate that Sterimar soothing nose cream is effective in nourishing, soothing, protecting, and moisturizing the nasolabial zone, and is well tolerated.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70107","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lip Sonoanatomy and Relevance to Aesthetic Filler Injections: A Pictorial Review","authors":"Wei-Ting Wu,&nbsp;Ke-Vin Chang,&nbsp;Ondřej Naňka,&nbsp;Hsiang-Chi Chang,&nbsp;Vincenzo Ricci,&nbsp;Kamal Mezian,&nbsp;Levent Özçakar","doi":"10.1111/jocd.70164","DOIUrl":"https://doi.org/10.1111/jocd.70164","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Lips are central to facial aesthetics, influencing overall balance and harmony. Ultrasound has become a key tool for assessing lip musculature and neurovascular structures, particularly in aesthetic filler injections. By enhancing precision and safety, ultrasound is valuable in procedures addressing age-related lip changes, yet standardized scanning protocols remain underexplored.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This review examined lip anatomy, summarized ultrasound applications in aesthetic procedures, introduced a structured scanning protocol, and highlighted its role in guiding filler injections.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic search of PubMed, Scopus, Embase, and Web of Science was conducted up to August 1, 2024, using keywords related to ultrasound and lip anatomy. Studies involving human subjects or cadavers using ultrasound for lip assessment and injection guidance were included, whereas nonhuman studies, alternative imaging methods, and research unrelated to the lip region were excluded. Six studies met the criteria.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Ultrasound improves precision in lip injections by identifying key structures, including the superior and inferior labial arteries and the orbicularis oris muscle, reducing vascular risks. A structured scanning approach enhances procedural safety and efficacy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Ultrasound is a valuable tool in aesthetic lip procedures, improving accuracy and minimizing complications. Further research is needed to refine protocols and establish ultrasound as a standard practice in lip augmentation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70164","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Efficacy and Safety of Cryolipolysis in Reducing Local Adipose Tissue in Women—A Randomized Pilot Study","authors":"Wioleta Faruga-Lewicka,&nbsp;Wiktoria Staśkiewicz-Bartecka,&nbsp;Marek Kardas","doi":"10.1111/jocd.70149","DOIUrl":"https://doi.org/10.1111/jocd.70149","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Cryolipolysis was developed in 2007 as a method of reducing excessive adipose tissue using low temperatures. During the procedure, lipid crystallization occurs at temperatures much higher than the freezing point of water in the tissues. This is followed by the recruitment of macrophages, the number of which peaks at 4 weeks and disappears at about 3 months after treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>The study involved 15 women who were divided into a control group and a study group. All subjects completed the QEB questionnaire, had body circumference measurements taken, and had a body composition analysis performed before the start of therapy and 1 month after the end of therapy. The study group underwent three cryolipolysis treatments to the abdominal area, with a treatment duration of 45 min and a temperature of −8°C. Approval from the bioethics committee was obtained prior to the study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Comparing the results of the control group and the study group after 3 months of the study, differences in mean values of body fat, abdominal circumference, and BMI values are evident, while statistical analysis showed a significant difference in changes in BMI values (<i>p</i> &lt; 0.05), while changes in body fat were on the borderline of statistical significance (<i>p</i> = 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The study confirms that cryolipolysis is a safe method of reducing locally accumulated fat, especially in the abdominal area in women.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70149","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Port Wine Birthmark With Nude Tattoo Using Multiple Laser Modalities","authors":"Vincent Pecora,&nbsp;Emily Murphy,&nbsp;Pooja Sodha","doi":"10.1111/jocd.70178","DOIUrl":"https://doi.org/10.1111/jocd.70178","url":null,"abstract":"&lt;p&gt;Port wine birthmarks (PWB) are congenital capillary malformations that frequently occur on the face and neck [&lt;span&gt;1, 2&lt;/span&gt;]. Activating mutations in GNAQ and PI3K, along with other predisposing mutations in PWB, lead to dysregulated MAPK and PI3K signaling, triggering vascular ectasia and dilation [&lt;span&gt;2&lt;/span&gt;]. PWB are initially flat red macules or patches, but they progressively darken, undergo soft tissue hypertrophy, and develop vascular nodules into late childhood and adulthood [&lt;span&gt;2&lt;/span&gt;]. PWB are important to recognize given their cosmetic impact, especially on the face, and possible associations with genetic syndromes, like Sturge–Weber. First-line treatments of PWB include the pulsed dye laser (PDL), which targets and destroys hemoglobin, causing necrosis of vessel walls [&lt;span&gt;2, 3&lt;/span&gt;]. One alternative treatment is medical tattooing to alter the skin color and camouflage the PWB [&lt;span&gt;4&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;However, the use of pulsed dye laser therapy to treat cutaneous pathologies with tattoo overlays has remained controversial. High energy, short-pulsed dye lasers have specifically been found to increase the risk of irreversibly darkening cosmetic medical tattoos, leading to gray-black hyperpigmentation [&lt;span&gt;4&lt;/span&gt;]. In order to prevent adverse cosmetic outcomes in patients with pre-existing tattoos, recent therapies have utilized multimodal pulsed-dye laser therapy to selectively target dilated blood vessels and reduce diffuse erythema without destroying surrounding tissue [&lt;span&gt;5&lt;/span&gt;]. To date, there are no studies utilizing more than two simultaneous forms of multimodal laser therapy in the treatment of PWB. Here, we present a patient with a nude tattoo over a facial PWB that was successfully treated with multiple treatments of multimodal long-pulsed 755 nm Alexandrite, 595 nm pulsed dye laser, and 10 600 nm fractional carbon dioxide (CO&lt;sub&gt;2&lt;/sub&gt;) laser therapy on the same day. These results demonstrate that the presence of medical tattoos should not deter physicians from utilizing multimodal laser therapy to treat PWB.&lt;/p&gt;&lt;p&gt;A 64-year-old female presented with a facial PWB on the left temple, cheek, nose, and cutaneous upper lip. Six rounds of multimodal laser therapy were utilized, consisting of long-pulsed 755 nm Alexandrite (Lutronic Clarity) (Table 1) and long-pulsed 595 nm (Candela Vbeam) PDL (Table 2) with the addition of a 10 600 nm fractional CO&lt;sub&gt;2&lt;/sub&gt; laser (Candela Co2RE or DEKA DOT) laser three times (lasers were applied in this order). The treatments took place over 22 months.&lt;/p&gt;&lt;p&gt;During the third, fifth, and sixth treatment sessions, a 10 600 nm fractional CO&lt;sub&gt;2&lt;/sub&gt; laser was applied to the entire lesion in addition to the 755 nm Alexandrite and 595 nm PDL. The endpoint for the Alexandrite laser, which was applied to the purple hypertrophic tissue only, was a slow faint bluish darkening of the PWB, and the endpoint for the pulsed dye laser, applied to the entire lesion, was sustai","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Body Dysmorphic Disorder: A Systematic Review and Meta-Analysis","authors":"Angel Pérez-Buenfil,,&nbsp;Alejandra Morales-Sánchez","doi":"10.1111/jocd.70121","DOIUrl":"https://doi.org/10.1111/jocd.70121","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Body dysmorphic disorder (BDD) is characterized by a preoccupation with ≥ 1 perceived defects in physical appearance, which leads to social anxiety and avoidance. This excessive focus on appearance is linked to dissatisfaction with physical features, disappointment with cosmetic treatments, or frustration from not meeting perceived beauty standards.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The aim of this study was to determine the prevalence of BDD in dermatology, psychiatric, plastic surgery, general population, and world regions, as well as the prevalence of BDD using different diagnostic tools.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The authors conducted a systematic review of the literature in Medline via PubMed, Embase, and Latin American databases using MeSH terms “body dysmorphic disorder” and “prevalence” with filters for original and cross-sectional studies. Statistical analysis was performed using RStudio, and bias assessment was made using JBI Critical appraisal.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The overall prevalence of BDD in the general population was 17%, with higher rates in females than in males. The prevalence in plastic surgery patients was 24%. The highest prevalence of BDD was found in Latin America compared to other world regions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>BDD is a highly prevalent disorder, and increased awareness of the disease could improve its approach in plastic surgery and other medical fields.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing Social Media Trends in Cosmeceuticals: Insights From Google Trends and TikTok Analytics","authors":"Emily Correia,&nbsp;Jenna Mandel,&nbsp;Stephanie R. Jackson Cullison","doi":"10.1111/jocd.70172","DOIUrl":"https://doi.org/10.1111/jocd.70172","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Social media usage has surged, particularly since the COVID-19 pandemic. Dermatology invokes intense interest on social media, and cosmeceuticals are among the most trending topics, offering a unique space for dermatologists to share their expertise. By using tools like Google Trends and TikTok viewership, we aim to capture cosmeceutical trends to guide dermatologists' educational efforts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A Google Trends search from January 2004 to December 2023 was performed on retinol, bakuchiol, salicylic acid, glycolic acid, azelaic acid, hydroquinone, niacinamide, vitamin C serum, and hyaluronic acid. Trend lines were created for each term, and yearly percent differences in relative search volume index (SVI) were calculated. Relative interest for each cosmeceutical was analyzed, comparing the average SVI and TikTok views.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Google data shows sustained cosmeceutical search volume growth, with the largest increase from 2020 to 2021, coinciding with the COVID-19 pandemic. Cosmeceutical search volume corresponds with TikTok views. Both platforms demonstrate retinol as the most popular cosmeceutical, followed by hyaluronic acid, salicylic acid, glycolic acid, and vitamin C. Niacinamide has considerably more TikTok views compared to search interest. Bakuchiol was the least popular cosmeceutical.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The results reveal growing curiosity in cosmeceuticals, with interest correlating with consumers' views on social media. Awareness of skincare trends and growth in cosmeceutical interest empower dermatologists to anticipate patient inquiries and develop targeted education on product efficacy, cost effectiveness, and potential adverse reactions. Social media platforms are a possible space for dermatologists to engage with their patients and ensure dissemination of accurate cosmeceutical information.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70172","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Efficacy of Cutotype-Specific Personalized Topical Postbiotic Emollients in Females: A Single-Center, Cluster-Based, Pre-Post, Nonrandomized Controlled Trial in South Korea","authors":"Jiyeon Oh,&nbsp;Hyeon Jin Kim,&nbsp;Seoyeon Kyung,&nbsp;Jiseung Kang,&nbsp;So Min Kang,&nbsp;Dasom Jeon,&nbsp;Hye-Been Kim,&nbsp;HyungWoo Jo,&nbsp;Dong-Geol Lee,&nbsp;Dong Keon Yon","doi":"10.1111/jocd.70171","DOIUrl":"https://doi.org/10.1111/jocd.70171","url":null,"abstract":"&lt;p&gt;Skin, the human body's largest organ, hosts diverse microbiomes that regulate host immunity and maintain skin physiology [&lt;span&gt;1&lt;/span&gt;]. With advancements in metagenomics sequencing [&lt;span&gt;2&lt;/span&gt;], our understanding of microbial diversity and composition has significantly expanded. Its composition substantially varies between individuals; therefore, several studies have identified distinct cutotypes, or microbial sub-community clusters, in various ethnic populations [&lt;span&gt;3&lt;/span&gt;]. Our previous study established a comprehensive set of criteria to classify South Koreans' cutotype into 12 groups, considering both biophysical characteristics and microbiome composition [&lt;span&gt;4&lt;/span&gt;]. Each of the four skin groups—HL (high in tone/elasticity but low in oil/water), LH (low in tone/elasticity but high in oil/water), LL (low in both), HH (high in both)—is further stratified by age groups (young, 10–34 years; aging, 35–50 years; old, ≥ 51 years) [&lt;span&gt;4&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Given the complex interplay between the application of skincare products and the skin microbiome, it has been a novel objective for skincare products to maintain the skin microbiome. A previous study underscored the positive role of &lt;i&gt;Staphylococcus&lt;/i&gt; in increasing skin moisture, &lt;i&gt;Rothia&lt;/i&gt; in mitigating inflammation, &lt;i&gt;Cutibacterium&lt;/i&gt; in boosting nutrition, and &lt;i&gt;Streptococcus&lt;/i&gt; in improving elasticity [&lt;span&gt;5&lt;/span&gt;]. Skincare products tailored to an individual's cutotype may help address specific skin concerns more effectively by balancing the unique microbial system on the skin. Moreover, supporting the natural balance of the skin microbiome may further contribute to long-term skin health, maintaining the skin's protective barrier. Thus, we aimed to develop a microbiome postbiotic emollient, with different microbiome compositions for each cutotype, for Korean females with low tone/elasticity (i.e., LL and LH) and evaluate the effects of these products on skin hydration, elasticity, and tightness.&lt;/p&gt;&lt;p&gt;The mean age of the 126 participants was 45.06 (standardized deviation, 15.19) years, with ages ranging from 20 to 67 years. Baseline characteristics, such as sleep time, sunlight exposure, smoking, and phase of menstrual cycle, are detailed in Table 1. Improvements in skin hydration, elasticity, and tightness were observed across all age groups for both cutotypes (Table 2). The most significant increase in skin hydration was observed in aging LH, with a mean difference of 1.76 (95% CI, 1.25–2.28), whereas the greatest enhancements in elasticity and tightness were found in young LH (elasticity, 0.60 [95% CI, 0.33–0.87]; tightness, −1.03 [95% CI, −1.36 to −0.70]). Similarly, for LL, three age groups showed enhanced skin hydration, elasticity, and tightness. The most considerable increase in skin hydration was found in young LL (4.39 [95% CI, 2.52–6.26]), while aging LL exhibited the most significant enhancements in elasticity and tightness (elasticity, 0.72 [95% CI,","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70171","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compensatory Masseteric Bulging: A Novel Observation and Its Implications for Botulinum Neurotoxin Injection Techniques","authors":"Kyu-Ho Yi,&nbsp;Jovian Wan","doi":"10.1111/jocd.70090","DOIUrl":"https://doi.org/10.1111/jocd.70090","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Compensatory masseteric bulging, a newly identified complication, arises from repeated botulinum neurotoxin injections targeting the lower mid-masseter in East Asians. This phenomenon occurs when untreated upper muscle layers hypertrophy to compensate for weakened lower regions, disrupting facial symmetry. Traditional injection strategies, focused on the lower muscle bulk, overlook the masseter's complex three-layered anatomy (superficial, middle, deep), increasing asymmetry risks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>To prevent compensatory bulging, a retrograde, layered injection technique is proposed, distributing botulinum neurotoxin evenly across the upper, middle, and lower masseter. Ultrasound guidance enhances precision, ensuring toxin delivery to targeted layers while avoiding diffusion into adjacent muscles (e.g., risorius). Personalized dosing, adjusted for muscle thickness, activity, and treatment history, minimizes localized over-atrophy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A 34-year-old female developed upper masseter bulging after four lower mid-masseter botulinum toxin sessions over two years. Ultrasound revealed upper hypoechoic hypertrophy (12 mm thickness) contrasting with lower hyperechoic atrophy (5 mm). Injecting 50 units of LetibotulinumtoxinA into the upper masseter reduced hypertrophy (8 mm post-treatment), restoring facial symmetry.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Compensatory bulging underscores the need for holistic treatment addressing the entire muscle. Layered injections, guided by ultrasound and tailored dosing, mitigate asymmetry risks. Clinicians must adopt comprehensive strategies, integrating anatomical insights and advanced imaging, to optimize aesthetic outcomes in masseter hypertrophy management.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70090","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Acupuncture Effective in Diminishing Frown Lines? Evidence From a Randomized Controlled Trial","authors":"Hossein Haghir,&nbsp;Mohammad Javad Yazdanpanah,&nbsp;Seyed Kazem Farahmand,&nbsp;Majid Khadem-Rezaiyan,&nbsp;Hoda Azizi","doi":"10.1111/jocd.70144","DOIUrl":"https://doi.org/10.1111/jocd.70144","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>As life expectancy rises, facial rejuvenation has gained significance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This study aimed to evaluate the effects of body and facial acupuncture on reducing frown lines in women aged 30–59 in Mashhad, Iran.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients/Methods</h3>\u0000 \u0000 <p>In this double-arm randomized wait-list controlled trial, 72 participants were randomly assigned to either an intervention group, receiving facial and body acupuncture twice weekly for 6 weeks, or a control group with no treatment. The primary outcome was assessed using the Global Aesthetic Improvement Scale (GAIS) based on standardized photographs. Secondary outcomes included the Subject Satisfaction Scale (SSS) and Quality of Life (QOL) scores. Measurements were taken at three time points: week 0 (pre-treatment), week 7 (post-treatment), and week 12 (follow-up).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At week 7, 63% of the intervention group showed reduced frown lines at rest, and 72% during maximum frowning, significantly outperforming the control group. The improvements observed in the intervention group persisted at week 12 with 68.6% at rest and 57.2% at maximum frown. The SSS indicated that 72.2% and 62.9% of the intervention group were satisfied with their frown lines at weeks 7 and 12, respectively. Notable QOL improvements in social functioning were observed in the intervention group compared to the control group at both weeks 7 and 12. No serious adverse effects were reported; minor bleeding occurred in 4.86% of treatment sessions, resulting in bruising in 0.69%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study demonstrates that facial and body acupuncture is an effective and safe method for reducing frown lines.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>IRCT20230204057316N1 (https://irct.behdasht.gov.ir/trial/68408)</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vitro Lethal Effects of Benzyl Benzoate Concentrations of 25%, 10%, and 5% on Demodex folliculorum Mites: An Experimental Study With a Control Group","authors":"İlkay Can,&nbsp;Murat Durdu","doi":"10.1111/jocd.70175","DOIUrl":"https://doi.org/10.1111/jocd.70175","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Demodex mites have been implicated in the pathogenesis of many dermatologic diseases, especially rosacea. Although many case reports have been published about the treatment of skin diseases caused by <i>Demodex folliculorum</i> mite, no relevant treatment algorithm has been developed so far. In this context, we investigated the lethal effects of different doses of benzyl benzoate on this mite.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To compare the lethal effects of 3 different doses of benzyl benzoate on <i>Demodex folliculorum</i> mites with those of a control group consisting of immersion oil.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Waste samples collected from rosacea patients were included in the study. Four different groups of 20 mites were formed. Each group was exposed to 5%, 10%, and 25% concentrations of benzyl benzoate, respectively. Immersion oil was used as a negative control group. The movements of the mites were monitored with a digital microscope. The time to death of the mites was recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean time to death of mites was 26 ± 2,9, 120 ± 7.6, and 168 ± 15 min after application of benzyl benzoate at concentrations of 25%, 10%, and 5%, respectively. The mean time to death of mites in immersion oil applied as a negative control group was 192 ± 6.4 min. Among the study groups, only the 25% benzyl benzoate group had a statistically significantly shorter mean time to death compared to the control group (<i>p</i> = 0.03).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>While low concentrations of benzyl benzoate were ineffective in the treatment of demodicosis, benzyl benzoate at high concentrations, e.g., 25%, was found to be effective in its treatment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 4","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70175","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}