Journal of Cosmetic Dermatology最新文献

{"title":"When to change needles during neuromodulator injections-An electron-microscopy investigation into needle tip deformation.","authors":"Lisa Akintilo, Jeremy B Green, Joely Kaufman, Bahar Ghane-Motlagh, David L Freytag, Konstantin Frank, Michael Alfertshofer, Sebastian Cotofana","doi":"10.1111/jocd.16506","DOIUrl":"https://doi.org/10.1111/jocd.16506","url":null,"abstract":"<p><strong>Background: </strong>Neuromodulator injections are minimally invasive procedures performed across the globe. Despite their ubiquity, there is a dearth of information on whether and how needle tips used for neuromodulator procedures are deformed after repeated injections.</p><p><strong>Objective: </strong>We investigated the magnitude of needle tip deformation following sequential injection passes (3×, 5×, and 10×) during facial neuromodulator injections with three commonly used needle sizes (30G, 31G, and 32G).</p><p><strong>Methods: </strong>Neuromodulator was administered for four different aesthetic indications. Each collected needle was mounted and imaged in a Philips XL-30 Scanning electron microscope. Images were processed using ImageJ photo analysis software.</p><p><strong>Results: </strong>Forty-five needle tips were investigated. When comparing the facial regions of interest, a statistically significant difference in deformation percentage was found when injecting 10× (p = 0.044) with greatest damage after injecting the glabella (38.4%), followed by lateral canthus (27.9%), forehead (27.5%), and midface (23.1%). Independent of facial region targeted, the mean percentage of needle deformation at 3× was 14.8%, at 5× 19.6%, and at 10× 29.2% with p < 0.001. Smaller needle size corresponded to smaller percentage of damage.</p><p><strong>Conclusion: </strong>Exchanging needles after more than five injection passes will minimize needle deformation and likely increase injection precision.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microfocused Ultrasound in Regenerative Aesthetics: A Narrative Review on Mechanisms of Action and Clinical Outcomes.","authors":"Vasanop Vachiramon, Tatjana Pavicic, Gabriela Casabona, Jeremy B Green, Jennifer Levine, Je-Young Park, Julieta Spada, Mariana Muniz, John Akers, Matthew Jackson, Alec McCarthy","doi":"10.1111/jocd.16658","DOIUrl":"https://doi.org/10.1111/jocd.16658","url":null,"abstract":"<p><strong>Background: </strong>Microfocused ultrasound with visualization (MFU-V) is widely used in aesthetic medicine for skin tightening and rejuvenation. However, its role in regenerative aesthetics and its precise mechanism of action are not fully understood.</p><p><strong>Objective: </strong>This narrative review aims to contextualize and articulate the mechanism of action of MFU-V, evaluate its role in regenerative aesthetics, and assess its effectiveness based on existing clinical, histological, and skin-mechanical studies.</p><p><strong>Methods: </strong>A comprehensive literature search was performed to collect and analyze studies on MFU's biological mechanisms, clinical outcomes, and impact on extracellular matrix (ECM) regeneration. The review integrates findings from clinical trials, histological analyses, and biomechanical assessments to provide a cohesive understanding of MFU-V's role in aesthetic medicine.</p><p><strong>Results: </strong>MFU-V emits focused ultrasound energy that penetrates multiple skin layers and the superficial musculoaponeurotic system, creating localized thermal coagulation points. These points initiate biological responses that recruit fibroblasts and stimulate the production of new collagen and elastin fibers. Enhanced ECM protein synthesis leads to significant improvements in skin biomechanics and quality, reducing skin laxity and enhancing appearance. Clinical studies support these findings, showing improvements in skin firmness and texture following MFU-V treatment.</p><p><strong>Conclusion: </strong>Through analyzing the underlying biological mechanisms and the observable clinical outcomes, this narrative review sets the stage for a comprehensive understanding of the mechanism of action and role of MFU-V in regenerative aesthetics.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Pseudo-Ceramide Absorption Into the Stratum Corneum and Effects on Transepidermal Water Loss and the Ceramide Profile: A Randomized Controlled Trial.","authors":"Tomoki Akahane, Daisuke Watanabe, Eri Shimizu, Kosei Tanaka, Kazuhiro Kaizu","doi":"10.1111/jocd.16655","DOIUrl":"https://doi.org/10.1111/jocd.16655","url":null,"abstract":"<p><strong>Background: </strong>Changes in the level or profile of ceramides are associated with decreased stratum corneum (SC) barrier function. Topical application of a pseudo-ceramide (pCer)-containing moisturizer can improve barrier function. Additionally, pCer that absorbs into the SC may improve ceramide profiles.</p><p><strong>Aim: </strong>We investigated the relationship between pCer absorption into the SC and SC properties and determined the efficacy of a pCer-containing spray compared with that of a commercial spray without pCer.</p><p><strong>Patients/methods: </strong>Patients with self-perceived dry and sensitive skin and decreased barrier function (transepidermal water loss [TEWL] > 10 g/m²h) were randomized into two groups to topically apply a pCer-containing spray (test group; N = 33) or commercial spray without pCer (control group; N = 19) twice daily as a single-blind study. SC function and ceramide properties were investigated before and after 4 weeks of application.</p><p><strong>Results: </strong>In the test group, the ceramide (NP)/(NS) ratio proportionally increased with the pCer application level after 4 weeks of pCer-containing spray application. In the control group, there were no changes in SC function after topical application of the commercially available spray without pCer; however, the SC water content, TEWL, SC cell area, and scaling score improved in the test group. Furthermore, the changes in TEWL in the test group were significantly negatively correlated with the pCer application level.</p><p><strong>Conclusions: </strong>The efficacy of pCer-containing sprays for those who have sensitive skin with impaired barrier function was demonstrated. Furthermore, the improvement in SC barrier function induced by pCer may contribute to normalizing the SC ceramide profile.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications of Subcision for Acne Scarring: Experience From Clinical Practice and Review of the Literature.","authors":"Cong Sun, Davin Lim","doi":"10.1111/jocd.16629","DOIUrl":"https://doi.org/10.1111/jocd.16629","url":null,"abstract":"<p><strong>Background: </strong>Subcision is a surgical technique frequently used in the management of atrophic acne scars. The advent of new instruments, which includes sharp, blunt and energy assisted, have increased the efficacy of the procedure. The aim of this article was to review the safety of subcision in view of the new development in technology.</p><p><strong>Objective: </strong>To review the safety of subcision procedure for acne scarring and to provide clinicians with both evidence-based and practical information regarding the complications that can be associated with this procedure.</p><p><strong>Methods: </strong>A search through MEDLINE and Google Scholar was conducted for articles from January 2000 to January 2023 that involves subcision as a monotherapy for the treatment of acne scarring.</p><p><strong>Results: </strong>Ten articles involving subcision monotherapy were identified. The main complications of subcision were pain/tenderness, bruising, infection, formation of subcutaneous lumps, and dyspigmentation. Recommendations on how to minimize the complications from subcision have also been provided based on the clinical experience of the authors.</p><p><strong>Conclusion: </strong>Subcision is a safe treatment for acne scarring and clinicians need to be aware of the associated complication which occurs more with sharp instrumentation.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Psychosocial Exploration of Augmented Reality and Virtual Reality Apps in Cosmetic Procedures.","authors":"Diala Haykal, Hugues Cartier, Frederic Flament","doi":"10.1111/jocd.16612","DOIUrl":"https://doi.org/10.1111/jocd.16612","url":null,"abstract":"<p><strong>Background: </strong>The integration of augmented reality (AR) and virtual reality (VR) technologies into cosmetic dermatology offers new avenues for enhancing patient engagement, satisfaction, and decision-making. These immersive tools allow patients to better visualize the outcomes of procedures before treatment, improving communication with physicians and increasing confidence in cosmetic interventions. Despite the promise these technologies hold, there remain concerns regarding their accessibility, technical limitations, ethical challenges, and the potential for algorithmic bias. This commentary aims to explore the psychosocial implications of AR and VR in cosmetic consultations, focusing on their benefits and potential drawbacks.</p><p><strong>Methods: </strong>This commentary is based on a comprehensive review of literature on AR and VR applications in cosmetic procedures. The focus is on the psychosocial impact of these technologies, highlighting their influence on patient expectations, satisfaction, and decision-making. Studies that evaluate the integration of AR and VR into cosmetic consultations were analyzed to assess the benefits and challenges associated with these tools.</p><p><strong>Results: </strong>The analysis revealed that AR and VR significantly enhance patient involvement by allowing real-time visualization of treatment outcomes, which improves both understanding and satisfaction. Patients reported feeling more informed and confident in their decisions when using these tools during consultations. Furthermore, these technologies allow physicians to offer more personalized and detailed consultations, thus improving communication and alignment of expectations. However, several challenges remain: AR and VR technologies are expensive, their use can lead to discomfort (cybersickness), and algorithmic bias may skew patient perceptions, particularly in underrepresented demographic groups. There are also ethical concerns about data security and transparency of the algorithms used in these systems.</p><p><strong>Conclusion: </strong>AR and VR hold tremendous potential to revolutionize patient care in cosmetic dermatology by enhancing engagement, improving decision-making, and increasing overall patient satisfaction. Nonetheless, the full realization of these benefits will require addressing technical and ethical challenges through ongoing research, regulatory oversight, and collaboration between medical professionals and technology developers.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142563508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Halobacteria Formula Improvement of Skin Care-A Randomized, Double-Blind, Placebo-Controlled Clinical Study.","authors":"Leong-Perng Chan, Cheng Da-Long, Ya-Ping Tseng, Chia-Hua Liang","doi":"10.1111/jocd.16648","DOIUrl":"https://doi.org/10.1111/jocd.16648","url":null,"abstract":"<p><strong>Background: </strong>Halobacteria trueperi, an extremophilic microorganism thriving in high-salt environments, produces extracellular polysaccharides with potential anti-inflammatory and anti-aging properties. However, its clinical efficacy in skin improvement remains unclear. This study focuses on H. trueperi TCI66207, isolated from the Pacific Ocean at a depth of 662 m near Hualien, and its potential to enhance skin parameters, aiming to develop a novel functional formulation for pharmaceutical and cosmetic use.</p><p><strong>Aims: </strong>This sudy aims to evaluate the clinical efficacy of H. trueperi TCI66207 on various skin parameters and its potential for developing new functional cosmetic formulations.</p><p><strong>Patients/methods: </strong>A total of 40 subjects were recruited and randomly divided into two groups: the test group applied a serum containing H. trueperi TCI66207, while the placebo group used a basic serum. Subjects were instructed to apply the serum twice daily for 4 weeks. Skin parameters, including moisture, brightness, elasticity, pigmentation (spots and UV spots), texture, wrinkles, pores, and collagen density, were assessed before and after the 4-week application period.</p><p><strong>Results: </strong>After 4 weeks of using the H. trueperi TCI66207 serum, significant improvements were observed in all measured skin parameters compared to baseline, with notable enhancements in moisture, brightness, elasticity, texture, and collagen density, along with reductions in wrinkles, spots, and pore size.</p><p><strong>Conclusions: </strong>Halobacteria trueperi TCI66207 serum demonstrates a clear ability to improve skin conditions and delay signs of aging, making it a promising candidate for the development of new cosmetic formulations with potent anti-aging and skin-rejuvenating properties.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patchy Dermal Melanocytosis: Differential Diagnosis and Management.","authors":"Jiafang Zhu, Qingqing Cen, Rui Chang, Yue Han, Xiaoxi Lin","doi":"10.1111/jocd.16607","DOIUrl":"https://doi.org/10.1111/jocd.16607","url":null,"abstract":"<p><strong>Background: </strong>Nevus of Ito and Mongolian spots are distinct clinical presentations of patchy dermal melanocytosis, characterized by similar dermatological manifestations that can pose diagnostic difficulties for clinicians.</p><p><strong>Aim: </strong>This review aims to consolidate current understanding and research advancements on these conditions to facilitate clinical diagnosis, differential diagnosis, and management.</p><p><strong>Methods: </strong>A comprehensive search of databases including PubMed and Google Scholar was conducted, along with an analysis of pertinent literature retrieved from reference lists spanning nearly four decades.</p><p><strong>Results: </strong>Epidemiological, clinical, and pathological profiles exhibit nuanced differences between the two conditions, with unique expressions under electron microscopy and the regression possibility. It is noteworthy that most Mongolian spots naturally fade with advancing age, in contrast to nevus of Ito, which persist and may potentially evolve into malignant lesions. While picosecond laser treatment has shown greater efficacy than nanosecond lasers, the lower-energy approach holds particular promise in pediatric cases. The therapeutic landscape for patchy dermal melanocytosis is evolving, shifting from selective photothermal action to photomechanical or subcellular photothermal modalities.</p><p><strong>Conclusion: </strong>This review underscores the importance of meticulous clinical assessment and the potential of innovative therapeutic approaches in managing these conditions.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy-Based Skin Rejuvenation: A Review of Mechanisms and Thermal Effects.","authors":"Ximeng Jia, Yongqiang Feng","doi":"10.1111/jocd.16657","DOIUrl":"https://doi.org/10.1111/jocd.16657","url":null,"abstract":"<p><strong>Background: </strong>Energy-based photoelectric and ultrasonic devices are essential for skin rejuvenation and resurfacing in the field of plastic surgery and dermatology. Both functionality and appearance are impacted by factors that cause skin to age, and various energy types have variable skin penetration depths and modes of transmission.</p><p><strong>Aim: </strong>The objective is to advise safe and efficient antiaging treatment while precisely and sensitively controlling and assessing the extent of thermal damage to tissues caused by different kinds of energy-based devices.</p><p><strong>Methods: </strong>A literature search was conducted on PubMed to review the mechanisms of action and thermal effects of photoelectric and ultrasonic devices in skin remodeling applications.</p><p><strong>Results: </strong>This paper reviews the thermal effects of energy-based devices in skin resurfacing applications, including the tissue level and molecular biochemical level. It seeks to summarize the distribution form, depth of action, and influencing factors of thermal effects in combination with the mechanisms of action of various types of devices.</p><p><strong>Conclusion: </strong>Accurate control of thermal damage is crucial for safe and effective skin remodeling treatments. Thorough investigation of molecular biochemical indicators and signaling pathways is needed for real-time monitoring and prevention of severe thermal injury. Ongoing research and technological advancements will improve the accuracy and control of thermal damage during treatments.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison and Assessment of Anti-Inflammatory and Antioxidant Capacity Between EGCG and Phosphatidylcholine-Encapsulated EGCG.","authors":"Minjia Yuan, Lili Hu, Cuicui Zhu, Qi Li, Hang Tie, Haihua Ruan, Tao Wu, Hongyang Zhang, Liang Xu","doi":"10.1111/jocd.16628","DOIUrl":"https://doi.org/10.1111/jocd.16628","url":null,"abstract":"<p><strong>Aim: </strong>To compare and evaluate the differences between EGCG and phosphatidylcholine-encapsulated EGCG in terms of their anti-inflammatory and antioxidant capacities.</p><p><strong>Methods: </strong>In this study, transdermal absorption experiments were conducted to compare the absorption capacity of EGCG and phosphatidylcholine-encapsulated EGCG. Subsequently, the disparity in anti-inflammatory and antioxidant efficacy between EGCG and phosphatidylcholine-encapsulated EGCG were evaluated through cytotoxicity experiments, as well as the determination of cellular inflammatory factors and the measurement of ROS content under different treatment conditions.</p><p><strong>Results: </strong>The concentration of EGCG, encapsulated in phosphatidylcholine, in porcine skin is 40.76 ± 1.29 μg/cm², which is significantly higher than the concentration of EGCG alone (31.62 ± 2.01 μg/cm²). Also, the ability of phosphatidylcholine-encapsulated EGCG to suppress inflammatory factors such as tumor necrosis factor-α (TNF-α), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) was notably superior to that of EGCG alone. Both phosphatidylcholine-encapsulated EGCG and EGCG showed excellent ROS scavenging ability in terms of antioxidant capacity.</p><p><strong>Conclusion: </strong>The percutaneous absorption and anti-inflammatory impact of EGCG encapsulated within phosphatidylcholine were substantially enhanced when compared to EGCG by itself. Additionally, both formulations exhibited enhanced ROS scavenging capacities, albeit the variance between them was not pronounced. These insights furnish a vital theoretical underpinning for the utilization of phosphatidylcholine-encapsulated EGCG in cosmetic applications, specifically for fostering products with anti-inflammatory and antioxidant benefits.</p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Featured Cover","authors":"","doi":"10.1111/jocd.16659","DOIUrl":"https://doi.org/10.1111/jocd.16659","url":null,"abstract":"<p>The cover image is based on the article <i>Eighty-three facial landmarks for facial image alignment</i> by Weng Yu-Ching et al https://doi.org/10.1111/jocd.16449.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"23 11","pages":"i"},"PeriodicalIF":2.3,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16659","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142555371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}