Journal of Current Ophthalmology最新文献

{"title":"Two-Year Follow-Up of Idiopathic Acute Exudative Polymorphous Vitelliform Maculopathy: Case Report and Literature Review.","authors":"Khaled El Matri, Mohamed Foued Rmili, Ahmed Arfaoui, Ines Hachicha, Zouheir Chebbi, Camilia Chafter, Yousra Falfoul, Rim Bouraoui, Leila El Matri, Rim Limaiem","doi":"10.4103/joco.joco_138_25","DOIUrl":"10.4103/joco.joco_138_25","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of idiopathic acute exudative polymorphous vitelliform maculopathy (AEPVM), assessed with comprehensive multimodal imaging, with a 2-year follow-up.</p><p><strong>Methods: </strong>Observational case report and literature review.</p><p><strong>Results: </strong>A 43-year-old female presented with acute bilateral vision decrease. Funduscopy revealed multiple bilateral round yellowish lesions with a foveal vitelliform-like deposit. Lesions were both hyper- and hypoautofluorescent. They were hyperfluorescent on fluorescein angiography and hypofluorescent on indocyanine green angiography. Swept-source optical coherence tomography demonstrated bilateral macular thickening with subfoveal fluid and hyperreflective bleb-like deposits associated with photoreceptor outer segment shedding and ellipsoid thickening. Electrooculogram revealed an impaired retinal pigment epithelium function. An extensive workup excluded autoimmune, infectious, and malignant causes, supporting the diagnosis of idiopathic AEPVM. The patient was monitored closely without treatment and showed significant anatomical and visual improvement over 2 years.</p><p><strong>Conclusions: </strong>AEPVM is a rare acute disease with characteristic imaging findings. Despite the similarities with vitelliform macular dystrophies, family history and genetic workup are typically negative. Most cases resolve spontaneously, but recurrences may occur.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"462-467"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Muscle Biopsy in the Diagnosis and Management of Extraocular Muscle Pathologies.","authors":"Prithvi Vishwanath, Md Shahid Alam, Kirthi Koka, Bipasha Mukherjee","doi":"10.4103/joco.joco_210_25","DOIUrl":"10.4103/joco.joco_210_25","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the role of extraocular muscle (EOM) biopsy in diagnosing and managing patients presenting with EOM pathologies.</p><p><strong>Methods: </strong>A retrospective review of patient records for those who underwent EOM biopsy between January 2010 and August 2022 was conducted. Data collected included demographic details, initial diagnosis, radiological findings, response to initial treatment, histopathological reports of the specimen, and any changes in treatment modality following biopsy.</p><p><strong>Results: </strong>Twenty-three eyes of 18 patients were included. The mean age of the cohort was 42.4 ± 18.04 years, with a male preponderance (<i>n</i> = 10; 55.6%). Unilateral involvement was observed in 13 (72.22%) cases, and bilateral involvement in 5 (27.77%). Proptosis was the most common clinical presentation (<i>n</i> = 12; 66.6%). On imaging, the lateral rectus was the most frequently involved muscle (<i>n</i> = 11; 61%). Muscle biopsy confirmed the diagnosis as Idiopathic orbital inflammatory disease in 10 (55.55%) patients, dermoid in 2 (11.11%), and leiomyoma, amyloidosis, extranodal marginal zone lymphoma, benign reactive lymphoid hyperplasia, sarcoid granuloma, and carcinoid in 1 (5.55%) patient each.</p><p><strong>Conclusions: </strong>EOMs can be involved in a variety of orbital lesions. Muscle biopsy is indicated in patients with clinicoradiological ambiguity or poor response to initial treatment.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"449-454"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systemic Hemodynamics and Ocular Perfusion in Normal-Tension Glaucoma: Evaluation of Beta-Blocker Effect.","authors":"Kübra Özata Gündoğdu, Nilgün Özkan Aksoy, Seren Kaplan Güngördü","doi":"10.4103/joco.joco_336_25","DOIUrl":"10.4103/joco.joco_336_25","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the effects of topical treatments with and without beta-blockers on diurnal and nocturnal intraocular pressure (IOP), systemic blood pressure (BP), and ocular perfusion pressure (OPP) in patients with normal-tension glaucoma (NTG).</p><p><strong>Methods: </strong>NTG patients followed at the Glaucoma Unit of the Department of Ophthalmology, Sakarya University Training and Research Hospital between 2020 and 2025 were retrospectively analyzed. Patients receiving beta-blocker-containing therapy (Group 2, <i>n</i> = 21) and nonbeta-blocker therapy (Group 1, <i>n</i> = 18) were included. Twenty-four-hour IOP and systolic/diastolic BP (DBP) measurements were recorded, and OPP was calculated. Optical coherence tomography parameters and visual field tests were also evaluated.</p><p><strong>Results: </strong>Patients using beta-blockers had significantly lower diurnal and nocturnal systolic BP (SBP) compared to the nonbeta-blocker group (P₁= 0.012, P₂= 0.048). No significant differences were observed in DBP between groups during diurnal and nocturnal periods (<i>P</i> ₁= 0.126, <i>P</i> ₂= 0.255). There were no significant differences between groups in 24-h mean IOP values or IOP fluctuation (<i>P</i> ₁= 0.590, <i>P</i> ₂= 0.753). Diurnal OPP was significantly lower in the beta-blocker group, while nocturnal OPP did not differ between groups (<i>P</i> ₁= 0.012, <i>P</i> ₂= 0.258). Ganglion cell-inner plexiform layer thickness was higher in the nonbeta-blocker group (<i>P</i> = 0.012). No significant differences were observed in other structural or functional measurements (retinal nerve fiber layer, <i>P</i> = 0.599; mean deviation, <i>P</i> = 0.457; pattern standard deviation, <i>P</i> = 0.805).</p><p><strong>Conclusions: </strong>In NTG patients, beta-blocker use reduces diurnal SBP and diurnal OPP but has no significant effect on 24-h IOP or nocturnal OPP. These findings support the critical role of systemic hemodynamics and ocular perfusion in NTG progression and suggest that beta-blockers should be monitored carefully for OPP effects, especially in normotensive patients.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"395-399"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Metaverse in Ophthalmology: Application and Perceived Benefits, Challenges, Realistic Expectations, and Future Outlook.","authors":"Yazan Abubaker, Dana Mahameed, Abhimanyu S Ahuja, Yara Abukhaled, Aya Shokair, Nithya Boopathiraj, Ibrahim Qozat, Isabella V Wagner, P Connor Lentz, Pranav Vasu, Darby D Miller, Syril Dorairaj","doi":"10.4103/joco.joco_192_24","DOIUrl":"10.4103/joco.joco_192_24","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the potential of the metaverse, a three-dimensional platform merging physical and virtual realities (VRs), in advancing the field of ophthalmology. This study examines its applications in areas such as VR-based surgical training, augmented reality (AR)-assisted surgeries, artificial intelligence (AI)-driven diagnostics, and teleophthalmology. This review builds upon previous literature by integrating recent evidence and technological advancements, offering a more comprehensive analysis of particular applications and barriers in ophthalmology.</p><p><strong>Methods: </strong>Academic literature published between 2019 and 2024 was identified through searches in the PubMed database and Google Scholar search engine using relevant keywords. This review focused on studies discussing the application of the metaverse in health care and ophthalmology, with particular attention to key trends, emerging uses, technological features, and associated challenges.</p><p><strong>Results: </strong>A total of 60 studies were deemed relevant for inclusion in this review. The infrastructure supporting the Metaverse comprises technologies such as the Internet of Things, digital twins, mirror worlds, nonfungible tokens, blockchain technology, and lifelogging. Together, these technologies create immersive environments that users can access through VR headsets, AR glasses, and handheld controllers. The metaverse presents promising opportunities in ophthalmology, particularly in enhancing clinical training through simulators such as the EyeSi™ surgical simulator, VRmagic EyeSi Slit Lamp, and the HelpMeSee™ VR simulator. In addition, it facilitates remote consultations and improves diagnostic and treatment options, exemplified by tools such as the Vivid Vision™ system for amblyopia, the Microsoft HoloLens™ for navigating complex anatomical structures, and AI-based platforms for the early detection of diseases such as glaucoma and diabetic retinopathy. Furthermore, the metaverse may enhance patient education by simulating the visual effects of ophthalmic conditions and visualizing postoperative outcomes. However, challenges, including financial limitations, data security concerns, and cultural acceptance, must be addressed.</p><p><strong>Conclusions: </strong>A gradual and context-specific integration of the metaverse is essential, particularly in underdeveloped regions. As the metaverse evolves, it holds significant potential to transform the field of ophthalmology by promoting global collaboration and innovation, complementing traditional practices, and ensuring equitable access to advanced healthcare solutions.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"381-388"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Twelve-Month Visual and Anatomical Outcomes of Boston Type I Keratoprosthesis in Four Patients with Multiple Graft Failures and Severe Ocular Pathology.","authors":"Hamed Ghasemi, Pirouzeh Farsi, Amirsadra Zangouei, Hassan Hashemi","doi":"10.4103/joco.joco_204_25","DOIUrl":"10.4103/joco.joco_204_25","url":null,"abstract":"<p><strong>Purpose: </strong>To assess 12-month visual acuity, anatomic integrity, and complication rates after Boston Type I Keratoprosthesis (BKPro-I) implantation in eyes with multiple failed penetrating keratoplasties and complex anterior segment pathology.</p><p><strong>Methods: </strong>In this prospective case series, four eyes (mean age, 32 ± 9 years) received BKPro-I between January and June 2022. All surgeries employed polymethylmethacrylate front plates, customized titanium back plates, and a standardized perioperative regimen (IV cefazolin, topical vancomycin + levofloxacin, corticosteroid taper, nightly povidone-iodine, selective antifungal prophylaxis) with early 16 mm scleral lens fitting. Follow-up occurred at 3 days, 1 week, 2 weeks, monthly to 3 months, then quarterly to 12 months postoperatively. Primary outcomes were best-corrected visual acuity (BCVA), device retention, and sight-threatening complications.</p><p><strong>Results: </strong>At 12 months, all devices were retained. Functional success (BCVA ≥20/200) was achieved in 100% of eyes in 6 months; at 12 months, 75% reached ≥20/100 and 50% ≥20/60 (mean gain ≥5 ETDRS lines). Two eyes (50%) developed complications - retroprosthetic membranes, vitritis/suspected endophthalmitis, stromal melting, chronic hypotony, and silicone-oil leak - all managed without device loss; one eye's vision declined to finger counting at month 7 but remained ambulatory.</p><p><strong>Conclusions: </strong>BKPro-I yields excellent short-term visual rehabilitation and perfect retention in highly complex eyes. However, a 50% complication rate mandates rigorous patient selection, standardized perioperative protocols, and lifelong multidisciplinary follow-up.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"455-461"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural, Vascular, and Functional Correlations in Advanced Glaucoma.","authors":"Kübra Özata Gündoğdu, Nilgün Özkan Aksoy, Merve Nur Mutlu","doi":"10.4103/joco.joco_323_25","DOIUrl":"10.4103/joco.joco_323_25","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the correlation between structural tests - optical coherence tomography (OCT) and OCT angiography (OCTA) - and the functional visual field test (VFT) in patients with advanced-stage glaucoma.</p><p><strong>Methods: </strong>This retrospective observational study included patients with a mean deviation (MD) worse than -12 dB on the 24-2 VFT. Patients with a history of intraocular surgery within the previous 6 months or with unreliable OCT, OCTA, or VFT results were excluded. For each patient, best-corrected visual acuity (BCVA), retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness (via OCT), radial peripapillary capillary vessel density (VD) of the optic disc, and superficial/deep macular VD (via OCTA) were assessed. Functional parameters included MD and pattern standard deviation from VFT. Correlations between structural and functional parameters were analyzed.</p><p><strong>Results: </strong>The study included 31 eyes of 20 patients (mean age: 68.81 ± 8.19 years; 65% male). Diagnoses per eye were pseudoexfoliative glaucoma (<i>n</i> = 14), primary open-angle glaucoma (<i>n</i> = 11), normal-tension glaucoma (<i>n</i> = 4), and pigmentary glaucoma (<i>n</i> = 2). The mean MD was -16.78 ± 7.46 dB. Moderate correlations were found between RNFL and GCC thicknesses, peripapillary and macular VD, and visual field indices. BCVA was also correlated with superior RNFL, GCC, and OCTA values.</p><p><strong>Conclusions: </strong>Significant correlations exist between structural and functional tests in advanced glaucoma. Combined use of OCT, OCTA, and VFT provides a more holistic and effective approach in disease monitoring and management.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"400-406"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Comment on \"Evaluation of Inflammatory Cytokines in Tears of Individuals with Dry Eye Related to Prolonged Computer Use\".","authors":"Rahul Bhargava","doi":"10.4103/joco.joco_41_26","DOIUrl":"10.4103/joco.joco_41_26","url":null,"abstract":"","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"473"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Corneal Surface Symmetry and Optical Aberrations after Conventional versus Brassiere Suture Technique in Upper Eyelid Blepharoplasty.","authors":"Elmas Yüksel Sükün, Sibel Sipahioğlu","doi":"10.4103/joco.joco_206_25","DOIUrl":"10.4103/joco.joco_206_25","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the effects of conventional blepharoplasty and the brassiere suture technique on corneal topography and optical aberrations.</p><p><strong>Methods: </strong>This retrospective comparative study included right eye data from 140 patients who underwent upper eyelid blepharoplasty for dermatochalasis between 2023 and 2025. Patients were divided into two groups based on the surgical technique: conventional blepharoplasty (<i>n</i> = 80) and brassiere suture technique (<i>n</i> = 60). Corneal topography and aberrometry were assessed preoperatively and at 3 months postoperatively using the Sirius topography system. Pre- and postoperative changes in 40 parameters were analyzed using the Wilcoxon signed-rank test, and intergroup comparisons of delta values (Δ) were performed using the Mann-Whitney <i>U</i>-test.</p><p><strong>Results: </strong>Neither technique resulted in significant changes in most corneal topography or aberrometry parameters (<i>P</i> > 0.05). However, the brassiere suture group demonstrated significant improvements in the superior irregularity ratio (ΔSIR) and total symmetry index (ΔTSI) (<i>P</i> = 0.006 and <i>P</i> = 0.018, respectively). In addition, a significant reduction was observed in vertical trefoil aberration at 6 mm (ΔTrefoil vertical, <i>P</i> = 0.031). No significant intergroup differences were found in other aberration or keratometric parameters.</p><p><strong>Conclusions: </strong>The brassiere suture technique demonstrated statistically significant improvements in corneal symmetry (SIR) and regularity (TSI) compared to conventional blepharoplasty. These findings indicate that the surgical approach may influence corneal surface characteristics. Further prospective studies are warranted to assess the clinical relevance of these optical changes.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"413-420"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Cerebellar Agenesis in a Child with Esotropia: A Case Report and Literature Review.","authors":"Mohammad Yaser Kiarudi, Alireza Radmanesh, Mahsa Sardabi, Amin Maleki","doi":"10.4103/joco.joco_307_25","DOIUrl":"10.4103/joco.joco_307_25","url":null,"abstract":"<p><strong>Purpose: </strong>To highlight the importance of neuroimaging in children with esotropia and developmental delay and to support botulinum toxin as a minimally invasive treatment option when major brain malformations are present.</p><p><strong>Methods: </strong>We describe an 18-month-old girl with infantile esotropia and mild developmental delay. Brain magnetic resonance imaging revealed near-complete cerebellar agenesis with a hypoplastic pons. Considering this malformation, bilateral medial rectus botulinum toxin injections (15 units in 0.1 mL per muscle, freehand technique) were performed instead of conventional strabismus surgery.</p><p><strong>Results: </strong>Ocular alignment improved with satisfactory cosmetic appearance, and stability was maintained throughout 4 months of follow-up. Genetic testing was not performed at the time because of follow-up limitations; however, it is recommended for further etiological clarification.</p><p><strong>Conclusion: </strong>This case highlights the importance of neuroimaging in children with esotropia and developmental delay and supports botulinum toxin as a minimally invasive treatment option when major brain malformations are present.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"468-471"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Ab-Interno Trabeculectomy and Trabecular Aspiration as a Simultaneous versus Sequential Addition to Phacoemulsification in Exfoliative Eyes.","authors":"David Kiessling, Alexandra Lappas, Thomas S Dietlein, Gernot F Roessler, Randolf A Widder","doi":"10.4103/joco.joco_226_25","DOIUrl":"10.4103/joco.joco_226_25","url":null,"abstract":"<p><strong>Purpose: </strong>To determine differing outcomes among pseudophakic patients with exfoliation glaucoma who underwent combined trabectome surgery and trabecular aspiration and phakic patients treated by a triple procedure with additional phacoemulsification.</p><p><strong>Methods: </strong>This retrospective study involved 75 eyes of 75 participants, of which 25 eyes received combined ab-interno trabeculectomy and trabecular aspiration (Trabectome + TA group), and 50 eyes underwent a triple procedure with additional phacoemulsification (triple group). The groups were matched at a 1:2 ratio, based on the following criteria: preoperative intraocular pressure (IOP), maximum known preoperative IOP, preoperative medication score, cup/disc ratio, follow-up time, and age. Successful surgery was defined by three scores: IOP at longest follow-up <21 mmHg (Score A) or <18 mmHg (Score B), without re-surgery and an IOP reduction >20% or IOP ≤15 mmHg without re-surgery and an IOP reduction ≥40% (Score C).</p><p><strong>Results: </strong>The preoperative IOP was 23.7 ± 5 mmHg, respectively, and decreased to 15.2 ± 4 mmHg in the triple group, which is significantly lower than postoperative IOP in the Trabectome + TA group, being 18.6 ± 8 mmHg during an average follow-up period of 33.4 ± 26 months (<i>P</i> = 0.02). The success rate in the triple group was significantly higher than in the Trabectome + TA group, according to Score A (78% vs. 40%) and Score B (70% vs. 36%). When aiming at a lower target IOP (Score C), the success rates did not differ significantly (36% vs. 24%).</p><p><strong>Conclusions: </strong>Cataract extraction, as a part of a triple procedure, seems to contribute to more effective IOP-lowering than trabectome surgery and trabecular aspiration alone in patients who underwent standalone phacoemulsification previously.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 4","pages":"389-394"},"PeriodicalIF":0.9,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}