Journal of Current Ophthalmology最新文献

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Hereditary Multiple Exostoses with Rare Ocular Finding: A Case Report. 遗传性多发性骨质疏松症伴罕见眼部病变:病例报告
IF 1.2
Journal of Current Ophthalmology Pub Date : 2024-08-10 eCollection Date: 2023-10-01 DOI: 10.4103/joco.joco_128_23
Shashi Tanwar, Nishtha Saini, Krutika Boriwal, Prashant Sharma
{"title":"Hereditary Multiple Exostoses with Rare Ocular Finding: A Case Report.","authors":"Shashi Tanwar, Nishtha Saini, Krutika Boriwal, Prashant Sharma","doi":"10.4103/joco.joco_128_23","DOIUrl":"https://doi.org/10.4103/joco.joco_128_23","url":null,"abstract":"<p><strong>Purpose: </strong>To study rare ocular findings in a rare case of hereditary multiple exostoses (HME) and to study HME in one family.</p><p><strong>Methods: </strong>HME is an autosomal dominant genetic disease characterized by the presence of multiple exostoses (osteochondromas). It is caused by mutations in two genes: exostosin-1 (EXT1) and exostosin-2 (EXT2). We report HME in a family over three generations. The index case was a 14-year-old female who presented with an ocular mass and multiple hard nodules in the upper and lower limbs. Family history revealed similar multiple nodules in the younger brother, father, and grandfather. Hence, the paternal family history for HME is positive. All the family members were examined. Family members who were diagnosed with HME had a series of radiology tests completed. Furthermore, the family members with HME were also seen by an orthopedic surgeon.</p><p><strong>Results: </strong>Family history and physical examination revealed multiple exostoses in the younger brother, father, and grandfather. They were all diagnosed with HME. The index case also had an ocular surface mass with scleral ectasia in the right eye.</p><p><strong>Conclusion: </strong>HME is a rare, genetic disorder. Cases of HME with ocular findings are rare. This patient has a paternal family history of HME and presents with an ocular surface mass.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Ocular Perfusion Pressure Values at Rest and during Resistance Exercise in Offspring of Glaucoma Patients. 青光眼患者后代在静息和阻力运动时的低眼部灌注压值
IF 1.2
Journal of Current Ophthalmology Pub Date : 2024-08-10 eCollection Date: 2023-10-01 DOI: 10.4103/joco.joco_207_23
Diana de Medeiros Andrade, Jordane Benedito Vargas Oliveira, Marta Halfeld Ferrari Alves Lacordia, Mateus Camaroti Laterza, Daniel Godoy Martinez
{"title":"Low Ocular Perfusion Pressure Values at Rest and during Resistance Exercise in Offspring of Glaucoma Patients.","authors":"Diana de Medeiros Andrade, Jordane Benedito Vargas Oliveira, Marta Halfeld Ferrari Alves Lacordia, Mateus Camaroti Laterza, Daniel Godoy Martinez","doi":"10.4103/joco.joco_207_23","DOIUrl":"https://doi.org/10.4103/joco.joco_207_23","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the ocular perfusion pressure (OPP) response during physical exercise in individuals with and without a family history (FH+, FH-) of glaucoma.</p><p><strong>Methods: </strong>Thirty-four subjects, divided into FH+ and FH- groups, realized 3 min at rest, 3 min of isometric handgrip exercise at 30% of maximal voluntary contraction, followed by 3 min of recovery. Blood pressure (Dixtal<sup>®</sup> automatic device) and intraocular pressure (Goldmann applanation tonometer) were measured during rest, exercise, and recovery. The mean OPP (mOPP) was calculated.</p><p><strong>Results: </strong>In the FH+ group (17 subjects), baseline mOPP values were significantly lower than in the FH- group (17 subjects) (right eye: <i>P</i> < 0.001, left eye: <i>P</i> < 0.001, respectively). During exercise, both the FH+ and FH- groups showed a similar increase in mOPP in both eyes (right eye: FH+: 38 ± 4 mmHg vs. 51 ± 7 mmHg, FH-: 48 ± 5 mmHg vs. 57 ± 9 mmHg, <i>P</i> < 0.001; left eye: FH+: 39 ± 3 mmHg vs. 51 ± 7 mmHg; FH-: 46 ± 5 mmHg vs. 58 ± 8 mmHg, <i>P</i> < 0.001, respectively). However, the FH+ group maintained significantly lower mOPP values compared to the FH- group in the right and left eyes (group effect: <i>P</i> = 0.002, <i>P</i> = 0.002, respectively). The percentage of increase in mOPP in the FH+ group was greater compared to the FH- group during exercise (right eye: 34.1% ± 15.9% vs. 22.1% ± 13.2%, respectively; <i>P</i> = 0.025; left eye: 33.2% ± 17.7% vs. 22.4% ± 13.7%, respectively, <i>P</i> = 0.056).</p><p><strong>Conclusions: </strong>mOPP increased during physical exercise in both groups, but the FH+ group had lower absolute values. In addition, the FH+ group appears to demonstrate a higher percentage increase in mOPP compared to the FH- group.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrophysiological and Visual Parameter Changes in Retinitis Pigmentosa Patients undergoing Autologous Platelet-Rich Plasma Therapy: A Randomized Control Trial. 接受自体富血小板血浆疗法的视网膜色素变性患者的电生理和视觉参数变化:随机对照试验
IF 1.5
Journal of Current Ophthalmology Pub Date : 2024-03-29 eCollection Date: 2023-07-01 DOI: 10.4103/joco.joco_216_22
Perwez Khan, Lubna Khan, Kumari Kanchan Kiran
{"title":"Electrophysiological and Visual Parameter Changes in Retinitis Pigmentosa Patients undergoing Autologous Platelet-Rich Plasma Therapy: A Randomized Control Trial.","authors":"Perwez Khan, Lubna Khan, Kumari Kanchan Kiran","doi":"10.4103/joco.joco_216_22","DOIUrl":"https://doi.org/10.4103/joco.joco_216_22","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the efficacy of autologous platelet-rich plasma (PRP) injections in suprachoroidal space and subtenon space in cases of retinitis pigmentosa, which is a genetic disease, leading to gradual loss of vision. Till date, no treatment is available.</p><p><strong>Methods: </strong>Seventy-eight eyes of 39 patients of retinitis pigmentosa having visual acuity ranging from reading of Early Treatment Diabetic Retinopathy Study (ETDRS) chart from 1 m onward to patients who were not able to read the ETDRS chart but whose visual acuity ranged from finger count close to face to <1 m were included in the study. The left and right eyes of each patient were randomized as the intervention eye and control eye. 0.2 mL of autologous PRP was injected in suprachoroidal space and 0.5 mL of PRP was injected in subtenon space of the intervention eye taking aseptic precautions. Injections were repeated at 15-day intervals up to 3 injections.</p><p><strong>Results: </strong>Majority of patients were in the age group of 18-30 years (20 cases) followed by 31-45 years (13 cases) and more than 45 years (6 cases). Intervention eyes showed a statistically significant improvement in visual acuity and multifocal electroretinography (mfERG). Improvement was noted in amplitude density latency and in ring ratio of mfERG. There was a significant improvement in best-corrected visual acuity (BCVA). However, no improvement in mfERG or BCVA was observed in the control group.</p><p><strong>Conclusions: </strong>Gene therapy may be the ultimate cure for retinitis pigmentosa, but it is unaffordable for many patients due to its high cost. PRP may be recognized as a modality to improve vision and stop further deterioration, especially in cases where functional vision is preserved. Negligible treatment costs and affordability will give power to economically disadvantaged patients.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11047807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Bilateral Retinal Pigment Epithelial Detachments in a Patient with Systemic Lupus Erythematosus: A Case Report. 一名系统性红斑狼疮患者的多发性双侧视网膜色素上皮脱落:病例报告。
IF 1.5
Journal of Current Ophthalmology Pub Date : 2024-03-29 eCollection Date: 2023-07-01 DOI: 10.4103/joco.joco_267_22
Renata Diniz Lemos, Ahmad Mohamad Ali Hamade, Leangelo Nicholas Hall, Maurício Abujamra Nascimento
{"title":"Multiple Bilateral Retinal Pigment Epithelial Detachments in a Patient with Systemic Lupus Erythematosus: A Case Report.","authors":"Renata Diniz Lemos, Ahmad Mohamad Ali Hamade, Leangelo Nicholas Hall, Maurício Abujamra Nascimento","doi":"10.4103/joco.joco_267_22","DOIUrl":"https://doi.org/10.4103/joco.joco_267_22","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of multiple bilateral retinal pigment epithelial detachments (PEDs) in a woman with systemic lupus erythematosus (SLE).</p><p><strong>Methods: </strong>Case Report.</p><p><strong>Results: </strong>A 28-year-old female with mild blurred bilateral vision in both eyes (OU) without pain or any other symptom was admitted to the hospital due to worsening renal function and uncontrolled high blood pressure (HBP). Best-corrected visual acuity (BCVA) was 20/30 and 20/40, right and left eyes, respectively. She had SLE, glucose-6-phosphate dehydrogenase deficiency, and immune thrombocytopenic purpura. BP was over 150/90 mmHg for more than 1.5 years, and she used corticosteroids at varying doses for more than 4 years. During hospitalization, she was taking prednisone 60 mg daily as Class IV lupus nephritis was diagnosed. On fundoscopy, she had a lacy retinal pattern, remarkably on the macula in OU. Spectral-domain optical coherence tomography revealed multiple bilateral serous PEDs and pachychoroid. Angiofluoresceinography displayed multiple pooling hyperfluorescence areas. Six months afterward, while she was on prednisolone 10 mg daily, and antihypertensive medications, BCVA was improved to 20/25 OU. Nevertheless, she had no retinal or choroidal changes. Her findings could be related to SLE choroidopathy, central serous chorioretinopathy-like disease, and/or hypertensive choroidopathy.</p><p><strong>Conclusions: </strong>Ocular involvement affects nearly one-third of SLE patients. The findings are variable and can include nearly any part of the eyeball. Multiple bilateral PEDs have been described in the literature; however, in this case, it is probably multifactorial and not only related to SLE.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11047803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypotony and Anterior Uveitis following Dual Therapy with Nivolumab and Ipilimumab for Metastatic Melanoma: A Case Report. 用 Nivolumab 和 Ipilimumab 双联疗法治疗转移性黑色素瘤后出现低眼压和前葡萄膜炎:病例报告。
IF 1.5
Journal of Current Ophthalmology Pub Date : 2024-03-29 eCollection Date: 2023-07-01 DOI: 10.4103/joco.joco_21_23
Nikhil S Patil, David Dudok, Sarit Khimdas
{"title":"Hypotony and Anterior Uveitis following Dual Therapy with Nivolumab and Ipilimumab for Metastatic Melanoma: A Case Report.","authors":"Nikhil S Patil, David Dudok, Sarit Khimdas","doi":"10.4103/joco.joco_21_23","DOIUrl":"https://doi.org/10.4103/joco.joco_21_23","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a rare case of hypotony and anterior uveitis following dual therapy with nivolumab and ipilimumab for metastatic melanoma.</p><p><strong>Methods: </strong>Case report.</p><p><strong>Results: </strong>Here, we present the case of a 64-year-old man taking nivolumab and ipilimumab dual therapy for BRAF+ (v-raf murine sarcoma viral oncogene homolog B1) metastatic melanoma. After treatment for 3 months, he presented to the ophthalmology clinic with bilateral intraocular pressures of 1 mmHg, bilateral keratic precipitates, cataracts, posterior synechiae, and anterior chamber inflammation. He improved with topical medications and the cessation of immunotherapy.</p><p><strong>Conclusions: </strong>Immunotherapies are a novel class of chemotherapy that has increased in prevalence for the treatment of numerous malignancies. There are many rare complications from these medications that are sparsely reported. Knowledge of ocular hypotony as a potential consequence of nivolumab and ipilimumab is important, particularly as it may arise months after treatment initiation and necessitate immunotherapy cessation.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11047816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Discriminatory Ability of Ganglion Cell Inner Plexiform Layer Complex Thickness in Patients with Preperimetric Glaucoma. 近视前青光眼患者神经节细胞内丛状层复层厚度的判别能力
IF 1.5
Journal of Current Ophthalmology Pub Date : 2024-03-29 eCollection Date: 2023-07-01 DOI: 10.4103/joco.joco_124_23
Bhavya Mehta, Somesh Ranjan, Vinod Sharma, Neha Singh, Nidhi Raghav, Acid Dholakia, Rahul Bhargava, P Laxmi Sireesha Reddy, Pooja Bargujar
{"title":"The Discriminatory Ability of Ganglion Cell Inner Plexiform Layer Complex Thickness in Patients with Preperimetric Glaucoma.","authors":"Bhavya Mehta, Somesh Ranjan, Vinod Sharma, Neha Singh, Nidhi Raghav, Acid Dholakia, Rahul Bhargava, P Laxmi Sireesha Reddy, Pooja Bargujar","doi":"10.4103/joco.joco_124_23","DOIUrl":"https://doi.org/10.4103/joco.joco_124_23","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate diagnostic performance of ganglion cell inner plexiform layer (GCIPL) and retinal nerve fiber layer (RNFL) parameters measured with Cirrus high-definition optical coherence tomography (OCT) in patients with preperimetric glaucoma.</p><p><strong>Methods: </strong>In this multicenter cross-sectional study, 150 eyes of 83 patients with preperimetric glaucoma were compared with 200 eyes of age and sex matched healthy subjects. All patients had visual field testing and OCT scanning of GCIPL and RNFL in all quadrants. The independent Samples <i>t</i>-test was used to determine if a difference exists between the means of two independent groups on a continuous dependent variable. The area under the receiver operating characteristic (ROC) curve (AUC) of each parameter was calculated for discriminatory ability between normal controls and preperimetric glaucoma. The sensitivity and specificity were estimated by point coordinates on ROC curve.</p><p><strong>Results: </strong>The best parameters for distinguishing preperimetric glaucoma from healthy eyes were the combined average GCIPL + average RNFL, followed by average RNFL + GCIPL (inferotemporal), and average RNFL + GCIPL (minimum). The GCIPL parameters with the highest to lowest AUC (in decreasing order) were inferotemporal, followed by average, minimum, superior, inferior, superonasal, inferonasal, superotemporal, and quadrants. The RNFL parameters with the highest to lowest AUC (in decreasing order) were average, followed by nasal, temporal, superior, and inferior quadrants. The sensitivity of combined GCIPL + RNFL parameters ranged 85%-88% and the specificity ranged 76%-88%. The sensitivity for RNFL parameters ranged 80%-90% and the specificity ranged 64%-88%.</p><p><strong>Conclusion: </strong>GCIPL and RNFL have good discriminatory ability; the sensitivity and specificity increase when both parameters are combined for early detection of glaucoma.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11047817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eyedrop Instillation Techniques, Difficulties, and Currently Available Solutions: A Literature Review. 眼药水滴注技术、困难和现有解决方案:文献综述。
IF 1.5
Journal of Current Ophthalmology Pub Date : 2024-03-29 eCollection Date: 2023-07-01 DOI: 10.4103/joco.joco_308_22
Rohan Dadak, Amin Hatamnejad, Nikhil S Patil, Hongbo Qiu, Toby Y B Chan, Jaspreet Rayat
{"title":"Eyedrop Instillation Techniques, Difficulties, and Currently Available Solutions: A Literature Review.","authors":"Rohan Dadak, Amin Hatamnejad, Nikhil S Patil, Hongbo Qiu, Toby Y B Chan, Jaspreet Rayat","doi":"10.4103/joco.joco_308_22","DOIUrl":"https://doi.org/10.4103/joco.joco_308_22","url":null,"abstract":"<p><strong>Purpose: </strong>To review current eyedrop instillation techniques, common difficulties faced by patients instilling eyedrops, available eyedrop assistive devices, and patient education regarding eyedrop instillation.</p><p><strong>Methods: </strong>PubMed, Embase, and Google Scholar were searched from conception until June 2022 for articles on eyedrop instillation difficulties, techniques, tools, and patient education.</p><p><strong>Results: </strong>Instillation involves pulling down the lower eyelids and placing drops on the corneal surface or conjunctival fornix, followed by closing of the eyelids for about 1 min. Examples of techniques include eyelid closure and nasolacrimal obstruction techniques. Patients encounter many difficulties when administering eyedrops, including but not limited to poor visibility, squeezing the dropper bottle, aiming the bottle, and accidentally blinking. However, devices are available that assist with aim and dropper compression-force reduction in eyedrop instillation. These can be particularly useful in patient demographics with diminished manual dexterity or the ability to generate force from their fingers. Furthermore, despite patient education in eyedrop instillation not being a common practice, it has been found that adequate patient education can lead to significant improvement in eyedrop instillation technique.</p><p><strong>Conclusions: </strong>While many factors are associated with poor eyedrop instillation technique, there are many solutions available including assistive devices and proper instillation education.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11047814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postkeratoplasty Corneal Plaques: A Case Series. 角膜塑形术后角膜斑块:病例系列。
IF 1.5
Journal of Current Ophthalmology Pub Date : 2024-03-29 eCollection Date: 2023-07-01 DOI: 10.4103/joco.joco_315_22
Mohamed Bahgat Badawi Goweida, Mohamed Aly Kolaib, Wael Abdel Rahman El-Menawy, Amr Fathi Abuelkheir, Alaa Atef Ghaith
{"title":"Postkeratoplasty Corneal Plaques: A Case Series.","authors":"Mohamed Bahgat Badawi Goweida, Mohamed Aly Kolaib, Wael Abdel Rahman El-Menawy, Amr Fathi Abuelkheir, Alaa Atef Ghaith","doi":"10.4103/joco.joco_315_22","DOIUrl":"https://doi.org/10.4103/joco.joco_315_22","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the risk factors and management of corneal plaques formed after keratoplasty.</p><p><strong>Methods: </strong>In this retrospective study, medical records of all eyes with plaques formed on top of corneal grafts performed in the period between January 2014 and January 2022 were reviewed. The retrieved data included prekeratoplasty corneal pathology, ocular risk factors, operative data and complications, plaque management, and chemical composition of the plaques using infrared spectrometer.</p><p><strong>Results: </strong>Thirteen eyes were included in this study. Predisposing ocular comorbidities included ocular surface disorders with variable degrees of dry eye in nine patients, rheumatoid arthritis in three patients, history of herpetic keratitis in two eyes, and cicatrizing conjunctivitis in two patients. Surgical excision and amniotic membrane transplantation (AMT) were performed in 12 eyes. Postoperatively, five eyes showed recurrence after excision, two eyes developed graft vascularization and scarring, and one eye showed persistent epithelial defect and graft scarring, whereas four eyes showed complete epithelialization with mild haze. Rekeratoplasty and AMT were performed in two eyes with no plaque recurrence. Chemical analysis using infrared spectrometry showed that the plaques consisted of ammonium magnesium phosphate and calcium phosphate carbonate in 9 (75%) cases and pure mucus in 3 (25%) cases.</p><p><strong>Conclusions: </strong>Postkeratoplasty corneal plaque formation is an underestimated complication of keratoplasty that may occur after persistent epithelial defects. Ocular surface disorders are the primary predisposing risk factors. In our experience, the prognosis after medical treatment or surgical scraping is guarded, and regrafting can be the only solution to restore graft clarity.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11047806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective Randomized Study Comparing 27-Gauge Vitrectomy to 23-Gauge Vitrectomy for Epiretinal Membranes and Full-Thickness Macular Holes. 比较 27 号玻璃体切除术和 23 号玻璃体切除术治疗视网膜外膜和全厚黄斑孔的前瞻性随机研究。
IF 1.5
Journal of Current Ophthalmology Pub Date : 2024-03-29 eCollection Date: 2023-07-01 DOI: 10.4103/joco.joco_318_22
Luigi Caretti, Giulia Pillon, Giacomo Verzola, Cristina Monterosso, Martina Formisano
{"title":"A Prospective Randomized Study Comparing 27-Gauge Vitrectomy to 23-Gauge Vitrectomy for Epiretinal Membranes and Full-Thickness Macular Holes.","authors":"Luigi Caretti, Giulia Pillon, Giacomo Verzola, Cristina Monterosso, Martina Formisano","doi":"10.4103/joco.joco_318_22","DOIUrl":"https://doi.org/10.4103/joco.joco_318_22","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the surgical and clinical outcomes of 27-gauge vitrectomy and 23-gauge vitrectomy.</p><p><strong>Methods: </strong>We conducted a single-center, prospective, randomized study. Fifty-three patients affected by vitreoretinal interface disorders (epiretinal membranes and macular holes) were randomly scheduled to undergo 27-gauge (28 patients) or 23-gauge (25 patients) pars plana vitrectomy. The presence of any potential factor of increased baseline inflammation or eye anatomy influencing the surgery was criteria for exclusion. The time of surgery, postoperative intraocular pressure (IOP), state of sclerotomy wounds, rate of complications, postoperative pain, and indicators of inflammation were studied. We also introduced a new parameter to compare intraocular inflammation after surgery, given by the change in the number of intraretinal hyperreflective foci (HRF).</p><p><strong>Results: </strong>The 27-gauge vitrectomy was 1.28 min longer than 23-gauge vitrectomy (<i>P</i> < 0.05). The day after surgery, the mean IOP value was significantly higher in the 27-gauge group (16.12 mmHg versus 13.04 mmHg in the 23-gauge group,<i>P</i> < 0.05), but this difference disappeared in successive follow-ups and the sclerotomy wounds closed after 2 weeks in the both groups. The rate of postoperative hypotony did not significantly differ in the two groups (10.71% in the 27-gauge group and 8% in the 23-gauge group the day after the surgery,<i>P</i> = 0.94). Less postoperative eye redness was seen in 27-gauge eyes (value 1 on the scale) compared to 23-gauge (value 2 on the scale) (<i>P</i> < 0.05), but there was no significant difference in intraocular inflammation (cells, Tyndall, and number of HRF,<i>P</i> > 0.05 for all).</p><p><strong>Conclusions: </strong>The 27-gauge vitrectomy may have better outcomes in terms of IOP maintenance and cause less redness after the surgery but with a slightly prolonged surgery time and no other differences under other parameters (inflammation, rate of complications, postoperative pain, visual gain, and closure of the sclerotomy wounds).</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11047808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Survey Assessment of Individual and Occupational Factors Associated with Musculoskeletal Disorders among Indian Ophthalmologists. 对印度眼科医生中与肌肉骨骼疾病相关的个人和职业因素进行数字调查评估。
IF 1.5
Journal of Current Ophthalmology Pub Date : 2024-03-29 eCollection Date: 2023-07-01 DOI: 10.4103/joco.joco_46_23
Roshni Robert, Mahesh Babu, N A Sudhakar, B Sumanth
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