Journal of Current Ophthalmology最新文献

{"title":"Double Retina Sign: A New Optical Coherence Tomography Finding in Combined Hamartoma of the Retina and Retinal Pigment Epithelium.","authors":"Masood Naseripour,&nbsp;Ahad Sedaghat,&nbsp;Arzhang Gordiz,&nbsp;Reza Mirshahi","doi":"10.4103/joco.joco_30_22","DOIUrl":"https://doi.org/10.4103/joco.joco_30_22","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a case of combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) with peculiar optical coherence tomography (OCT) findings.</p><p><strong>Methods: </strong>Case report.</p><p><strong>Results: </strong>A 7-year-old girl with a history of decreased visual acuity in the left eye since early childhood presented with pigmented epiretinal membrane in favor of CHRRPE based on clinical and paraclinical findings. In OCT images, an area of retinal defect was noted, and the retina doubled up on itself near the defect (double retina sign).</p><p><strong>Conclusion: </strong>Careful examination of OCT images in patients with CHRRPE can reveal new findings.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"35 1","pages":"90-92"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e9/4b/JCO-35-90.PMC10481987.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10189118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal Ectasia after Laser-Assisted Small-Incision Lenticule Extraction: The Case for an Enhanced Ectasia Risk Assessment.","authors":"Siamak Zarei-Ghanavati, Samira Hassanzadeh, Renato Ambrósio","doi":"10.4103/joco.joco_79_22","DOIUrl":"10.4103/joco.joco_79_22","url":null,"abstract":"<p><strong>Purpose: </strong>To present a case of asymmetric progressive corneal ectasia following femtosecond laser-assisted small-incision lenticule extraction.</p><p><strong>Methods: </strong>After obtaining a patient's consent, preoperative and postoperative findings were represented in this case report.</p><p><strong>Results: </strong>A 29-year-old woman presented with normal preoperative Placido disk-based corneal topography and tomographic findings. The corrected refractive error was -4.00 and -4.50 -1.00 × 177 in the right and left eye, respectively, with a maximal lenticule thickness of 87 and 115 μm OD/OS. Twenty months postoperatively, the patient presented with decreased vision in the left eye and mild ectatic changes in corneal shape in both eyes. The retrospective evaluation of the integrated rotating Scheimpflug tomography (Pentacam; Oculus, Wetzlar, Germany) and corneal biomechanical (Corvis ST) assessment revealed moderate susceptibility for corneal ectasia in the right eye and a significant corneal ectasia in the left eye.</p><p><strong>Conclusion: </strong>This case corroborates the need for an enhanced multimodal approach to characterize the risk for postoperative corneal ectasia after laser vision correction.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 3","pages":"357-363"},"PeriodicalIF":1.2,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/b8/JCO-34-357.PMC9832456.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10536102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal Biomechanical Changes after Corneal Cross-Linking in Patients with Keratoconus.","authors":"Adel Hamid,&nbsp;Hamidreza Jahadi-Hosseini,&nbsp;Mohammad Reza Khalili,&nbsp;Hamidreza Jahanbani-Ardakani","doi":"10.4103/joco.joco_177_21","DOIUrl":"https://doi.org/10.4103/joco.joco_177_21","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the changes in biomechanical properties of the cornea using the Corvis ST device after the treatment of keratoconus patients with ultraviolet-A/riboflavin corneal cross-linking (CXL).</p><p><strong>Methods: </strong>Thirty-seven eyes from 37 consecutive patients with progressive keratoconus were included in this prospective observational case series. Corneal biomechanical parameters including the length of the applanated cornea (L1 and L2), corneal movement velocity during applanation (V1 and V2) at the moment of the first and second applanation, deformation amplitude (DA), distance between bending points of the cornea points of the cornea (PD), and concave radius of curvature (R) at the point of the highest concavity were recorded using the Corvis ST at baseline, 3 months, and 1 year after CXL.</p><p><strong>Results: </strong>The mean age of the patients was 23.27 years (range, 19-31 years). Among CorVis ST corneal biomechanical parameters, L1, DA, PD, and R at the point of the highest concavity did not change significantly. The length of the applanated cornea at the moment of second applanation (L2) showed a significant change 3 months after CXL, but no significant difference was found between the 3-month and 1-year values of this parameter. Corneal movement velocity during applanation (V1 and V2) did not change 3 months after doing CXL, but the changes in these parameters were significant 1 year after CXL.</p><p><strong>Conclusions: </strong>Although the CorVis ST device may detect changes in some biomechanical properties of cornea after the treatment of keratoconus patients with CXL, many parameters remain unchanged, and this device cannot readily be used to find the effects of CXL.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 4","pages":"409-413"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4a/bb/JCO-34-409.PMC10170983.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9469879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of Missed Diagnosis of Primary Open-Angle Glaucoma by Eye Care Providers.","authors":"Azadeh Doozandeh,&nbsp;Shahin Yazdani,&nbsp;Mohammad Pakravan,&nbsp;Zohreh Ghasemi,&nbsp;Kiana Hassanpour,&nbsp;Mehdi Hatami,&nbsp;Iman Ansari","doi":"10.4103/joco.joco_296_22","DOIUrl":"https://doi.org/10.4103/joco.joco_296_22","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy of opportunistic case finding in glaucoma detection and to determine factors associated with failure of glaucoma detection by eye health providers.</p><p><strong>Methods: </strong>This study was conducted on 154 new definite primary open-angle glaucoma (POAG) patients presenting to our glaucoma clinic. A questionnaire was prepared to determine if these subjects had sought eye care up to 12 months before presentation. The type of eye care provider and the principal reason for the visit were probed. The primary outcome measure was the frequency of a correct glaucoma diagnosis in their index visit. The secondary outcomes were factors associated with missed POAG diagnosis.</p><p><strong>Results: </strong>The great majority of study subjects (132 cases, 85.7%) had sought at least one ocular examination within 1 year before presentation. Among these patients, 73 cases (55.3%) had remained undiagnosed after the examination. Among the probed variables, age, gender, visual acuity, visual field defects, intraocular pressure, cup/disc ratio, nerve fiber layer thickness of the worse eye at presentation, and family history of glaucoma were comparable between correctly diagnosed and missed POAGs. The only factors significantly associated with missed POAG diagnosis were lack of significant refractive errors and visiting an optometrist rather than an ophthalmologist.</p><p><strong>Conclusions: </strong>The efficacy of opportunistic case finding for POAG seems to be less than ideal in our settings. Lack of a significant refractive error and visiting an optometrist rather than an ophthalmologist were associated with a missed diagnosis of POAG. These observations reflect the need to adopt policies to improve glaucoma screening by eye care providers.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 4","pages":"404-408"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/13/c4/JCO-34-404.PMC10170989.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9469880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal Optical Coherence Tomography Angiography Findings following Retinoblastoma Treatment by Chemotherapy.","authors":"Hamid Riazi-Esfahani,&nbsp;Hadi Shamouli,&nbsp;Elias Khalili Pour,&nbsp;Kaveh Fadakar,&nbsp;Alireza Khodabandeh,&nbsp;Babak Masoomian,&nbsp;Vahid Hatami,&nbsp;Fariba Ghassemi","doi":"10.4103/joco.joco_323_21","DOIUrl":"https://doi.org/10.4103/joco.joco_323_21","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the macular microvascular changes after different kinds of chemotherapy in patients with extramacular retinoblastoma (RB).</p><p><strong>Methods: </strong>In this study, 28 eyes of 19 patients with bilateral RB treated with intravenous systemic chemotherapy (IVSC group) and 12 eyes of 12 patients with unilateral RB treated with intra-arterial chemotherapy (IAC group) were compared with 6 normal fellow eyes of 6 patients with unilateral RB treated with IVSC (IVSC fellow eye group), and 7 normal fellow eyes of 7 unilateral RB patients treated with IAC (IAC fellow eye group), as well as 12 age-matched normal eyes. Enhanced depth imaging optical coherence tomography measurements of central macular and subfoveal choroidal thickness (CMT and SFCT) as well as optical coherence tomography angiography measurements such as retinal superficial capillary density (SCD), deep capillary density (DCD), and choriocapillaris density were documented.</p><p><strong>Results: </strong>Images of 2 eyes in the IVSC group and 8 eyes in the IAC group were excluded from the final image analysis due to severe retinal atrophy. Overall, 26 eyes with bilateral RB treated with IVSC and 4 eyes of 4 patients with unilateral RB treated with IAC were compared with the mentioned control groups. Best-corrected visual acuity was 1.03 logMAR in the IAC patients compared to 0.46 logMAR in the IVSC group at the time of imaging. While the CMT and SFCT were lower in the IAC group in comparison with the IAC fellow eye and normal groups (<i>P</i> < 0.05 for all), no remarkable difference was observed between the IVSC group and the control groups based on the mentioned parameters. Although the SCD showed no significant difference between the IVSC and control groups, this parameter was significantly lower in the eyes receiving IAC relative to the corresponding fellow eye group (<i>P</i> = 0.042) and normal control eyes (<i>P</i> = 0.047). The mean DCD was considerably lower in both the treatment groups compared to the control groups (<i>P</i> < 0.05 for all).</p><p><strong>Conclusion: </strong>Our study showed a substantial decrease in SCD, DCD, CMT, and choroidal thickness in the IAC group, which may explain the lower visual outcome in this group.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 4","pages":"452-459"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c2/32/JCO-34-452.PMC10170976.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior Microphthalmos Pigmentary Retinopathy Syndrome with Angle-Closure Glaucoma: A Case Report.","authors":"Hela Sassi,&nbsp;Khaled Ammar,&nbsp;Meriem Ouederni,&nbsp;Monia Cheour","doi":"10.4103/joco.joco_145_22","DOIUrl":"https://doi.org/10.4103/joco.joco_145_22","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a particular form of posterior microphthalmos pigmentary retinopathy syndrome (PMPRS) with an atypical clinical presentation of pigment retinal dystrophy and an association to an inconstant complication which is angle-closure glaucoma (ACG).</p><p><strong>Methods: </strong>A 40-year-old male patient with ACG on maximal topical treatment was referred to our department for uncontrolled intraocular pressure. Best-corrected visual acuity was 2/10 in the right eye and light perception in the left eye. Intraocular pressure was 36 mmHg bilaterally. He had 360° peripheral anterior synechiae on gonioscopy. Fundus examination revealed total cupping with pale retinal lesions in both eyes and a few pigment deposits in the midperiphery of the right eye. Multimodal imaging was done.</p><p><strong>Results: </strong>Fundus autofluorescence revealed patchy areas of hypoautofluorescence. Optical coherence tomography (OCT) showed bilateral foveoschisis and macular folds. Anterior segment OCT showed a circumferential iridocorneal angle closure. Axial length measured with ultrasound biomicroscopy was 18.4 mm in the right eye and 18.1 in the left eye. Electroretinogram revealed attenuated scotopic responses. The patient was diagnosed with nanophthalmos-retinitis pigmentosa (RP)-foveoschisis syndrome complicated with ACG. A combined surgery with phacoemulsification - anterior vitrectomy - intraocular lens implantation and trabeculectomy was performed in both eyes with a satisfactory outcome.</p><p><strong>Conclusions: </strong>In its typical forms, PMPR syndrome is an association of nanophthalmos - RP - foveoschisis and optic nerve head (ONH) drusen. Incomplete phenotypes may lack ONH drusen or foveoschisis. Patients with PMPRS have to be screened for iridocorneal angle synechia and ACG.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 4","pages":"474-477"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/92/90/JCO-34-474.PMC10170979.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparison of the Mydriatic Efficacy of Tropicamide and Phenylephrine Eye Drops Administered as a Vaporized Spray in One Eye and Conventional Drop Instillation in the Other Eye in an Indian Pediatric Cohort.","authors":"P G Vinay,&nbsp;Sunayana Bhat,&nbsp;Meera Mary Mathews","doi":"10.4103/joco.joco_127_22","DOIUrl":"https://doi.org/10.4103/joco.joco_127_22","url":null,"abstract":"<p><strong>Purpose: </strong>To determine by serial measurements and compare the pupillary mydriasis effect of tropicamide and phenylephrine drops administered as a vaporized spray over closed lids in one eye and through conventional instillation of eye drops in the other eye in a pediatric cohort.</p><p><strong>Methods: </strong>This prospective study was conducted on healthy children aged 6-15 years. After visual assessment, investigator 1 examined the child for initial pupillary size. Investigator 2 instilled the drops in one eye and applied the spray to the other eye randomly, and the response of the child was noted using the Wong-Baker pain rating scale. The eyes receiving the spray and the eyes receiving drop instillation were considered as Groups 1 and 2, respectively. Subsequently, serial pupillary measurements were carried out every 10 min for up to 40 min by investigator 1. The patient compliance for the two methods of drug instillation was also compared.</p><p><strong>Results: </strong>The study comprised 80 eyes. At 40 min, both the groups showed no statistical difference in the mydriasis effect, with Group 1 showing 7.23 mm mydriasis and Group 2 showing 7.58 mm (<i>P</i> = 0.058). The analysis of the pain rating scale showed better compliance with the spray method of drug instillation, which was statistically significant (<i>P</i> = 0.044).</p><p><strong>Conclusions: </strong>Our study shows that spray application is a less invasive method for pupillary dilatation, which has better compliance and provides equally good dilatation as conventional methods. This study proves the efficacy of spray application in an Indian pediatric cohort.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 4","pages":"448-451"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7f/b6/JCO-34-448.PMC10170984.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9472963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Management of Consecutive Exotropia.","authors":"","doi":"10.4103/2452-2325.375102","DOIUrl":"https://doi.org/10.4103/2452-2325.375102","url":null,"abstract":"<p><p>[This corrects the article on p. 475 in vol. 33, PMID: 35128197.].</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 4","pages":"489"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/98/JCO-34-489.PMC10170980.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Malignant Glaucoma.","authors":"Reza Sadeghi,&nbsp;Ali Momeni,&nbsp;Ghasem Fakhraie,&nbsp;Yadollah Eslami,&nbsp;Reza Zarei,&nbsp;Zakieh Vahedian,&nbsp;Mona Safizadeh,&nbsp;Seyed Mehdi Tabatabaei","doi":"10.4103/joco.joco_147_22","DOIUrl":"https://doi.org/10.4103/joco.joco_147_22","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the outcomes of various invasive and noninvasive approaches to the treatment of malignant glaucoma.</p><p><strong>Methods: </strong>Glaucoma-related keywords were looked up in PubMed and Google Scholar, and related articles up to 2022 were used to put together this review article.</p><p><strong>Results: </strong>Numerous surgical methods and techniques have been introduced in the past few years. This review outlined current knowledge regarding the nonsurgical and surgical management of malignant glaucoma. In this regard, we first briefly outlined the clinical presentation, pathophysiology, and diagnosis of this disorder. Then, the current evidence on the management of malignant glaucoma was reviewed. Finally, we discuss the need for treatment of the other eye and the factors that might affect the outcome of surgical intervention.</p><p><strong>Conclusions: </strong>Fluid misdirection syndrome, or malignant glaucoma, is a severe disorder that can occur spontaneously due to surgical intervention. The pathophysiology of malignant glaucoma is complicated, and numerous theories exist about the underlying mechanisms that may contribute to the disease. Malignant glaucoma can be treated conservatively using medications, laser therapy, or surgery. Laser treatments and medical treatments have been adequate for the treatment of glaucoma, but the effects have generally been short-lived, and surgical treatment has proved to be the most effective. There have been a variety of surgical methods and techniques introduced. Still, none have been studied in a large proportion of patients as a control case to compare effectiveness, outcomes, and recurrence. Pars plana vitrectomy with irido-zonulo-capsulectomy still seems to have the best results.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 4","pages":"389-397"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/65/8a/JCO-34-389.PMC10170992.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9822299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Sedative, Hemodynamic, and Anesthetic Effect of Dexmedetomidine, Ketamine, and Etomidate on Cataract Surgery by Phacoemulsification Method: A Randomized Clinical Trial.","authors":"Bardia Moghisseh,&nbsp;Hesameddin Modir,&nbsp;Esmail Moshiri,&nbsp;Zahra Motaghinia,&nbsp;Mohammadreza Bozorgmanesh","doi":"10.4103/joco.joco_158_22","DOIUrl":"https://doi.org/10.4103/joco.joco_158_22","url":null,"abstract":"<p><strong>Purpose: </strong>To compare dexmedetomidine, ketamine, and etomidate in the induction of sedation and hemodynamic changes in patients undergoing cataract surgery by phacoemulsification method.</p><p><strong>Methods: </strong>This was a double-blind clinical trial study carried out on 128 patients. Using the block randomization method, the patients were divided into four equal groups (dexmedetomidine, ketamine, etomidate, and control). Mean arterial pressure, heart rate, and arterial oxygen saturation, Ramsay Sedation Score were recorded every 5 min intraoperatively, in recovery, and 1, 2, 4, and 6 h postoperatively. Moreover, the Aldrete score was measured in recovery time for discharge from the recovery room.</p><p><strong>Results: </strong>The mean age of participants was found to be 63.16 ± 6.07 years, and there was no statistically significant difference between the groups in terms of age, sex, and body mass index, SpO_2, and heart rate (<i>P</i> > 0.05). From 15 min after the start of surgery to 6 h postoperatively, the mean arterial pressure in the dexmedetomidine group was significantly lower than that in the other three groups, including ketamine, etomidate, and control (<i>P</i> < 0.05). The mean sedation score (Ramsay) during recovery and 1 h postoperatively was higher in the dexmedetomidine group compared with that in the control group, whereas the recovery time in the dexmedetomidine group was higher than that in the other groups (<i>P</i> < 0.001). In addition, the amount of propofol consumption in the two groups of dexmedetomidine and ketamine was significantly less than that in the etomidate and control groups (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>According to the results, dexmedetomidine caused better hemodynamic changes with more reduction in blood pressure and heart rate, and patients in the dexmedetomidine group did not require any specific medical treatment. Moreover, higher patient satisfaction and longer recovery duration were observed in the dexmedetomidine group than in the other study groups. As such, it is suggested that dexmedetomidine be used as an adjuvant in cataract surgery for more sedation, analgesia, and optimal intraoperative conditions.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"34 4","pages":"414-420"},"PeriodicalIF":1.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/91/47/JCO-34-414.PMC10170987.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9469876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}