Journal of Current Ophthalmology最新文献

{"title":"Assessing Curved Foraminotomy Rongeurs as an Effective Tool in Osteotomy Formation during Endoscopic Dacryocystorhinostomy.","authors":"Robert Hill, Alexander Tanner, Christopher Schulz, Meydan Ben Ishai, Saul N Rajak","doi":"10.4103/joco.joco_99_25","DOIUrl":"https://doi.org/10.4103/joco.joco_99_25","url":null,"abstract":"<p><strong>Purpose: </strong>To form an osteotomy in endoscopic dacryocystorhinostomy (endo-DCR); the thickness and angulation of the frontal process of the maxilla is a limiting factor often necessitating the use of powered instrumentation. Curved foraminotomy rongeurs might enhance surgical access and improve ostium formation.</p><p><strong>Methods: </strong>Endo-DCRs were performed by ophthalmic surgeons on 24 sides of 12 fresh frozen cadavers in an anatomy laboratory. Once the biggest possible ostium had been created with standard rongeurs, surgeons switched to curved foraminotomy rongeurs to further enlarge the ostium. At each change of instrument, all removed bone was weighed, and an experienced surgeon evaluated the percentage of lacrimal sac exposure. Wilcoxon signed-rank test determined if the curve rongeurs facilitated any significant difference in bone removal or sac exposure.</p><p><strong>Results: </strong>Straight rongeurs removed a median of 229.5 mg (195.2-276.5) of bone, with 60% (50-63.3) of the lacrimal sac exposed. With the addition of curved rongeurs during the same DCR, a median of 449.5 mg (380.5-589.2, <i>P</i> < 0.0001) of bone was removed, and 90% (78.8-100, <i>P</i> < 0.0001) of the lacrimal sac was exposed.</p><p><strong>Conclusion: </strong>There is a significant improvement in the amount of bone removed with the addition of curved foraminotomy rongeurs during endo-DCR, with greater exposure of the lacrimal sac. This demonstrates a promising advance in endo-DCR surgical instrumentation.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"359-362"},"PeriodicalIF":0.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal Vascularization Timeline following Intravitreal Bevacizumab Injection in Infants with Retinopathy of Prematurity: A Retrospective Study.","authors":"Nasser Shoeibi, Maryam Mousavi, Majid Abrishami, Seyedeh Maryam Hosseini, Mohammad-Reza Ansari-Astaneh, Mojtaba Abrishami, Ghodsieh Zamani, Elham Bakhtiari, Bahareh Gharib, Fatemeh Neghabi, Mehrdad Motamed Shariati","doi":"10.4103/joco.joco_189_25","DOIUrl":"https://doi.org/10.4103/joco.joco_189_25","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the timeline of retinal vascularization and associated risk factors in infants with retinopathy of prematurity (ROP) treated with intravitreal bevacizumab (IVB).</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at the ROP clinic of the Khatam Eye Hospital from 2014 to 2023. The study included preterm infants diagnosed with ROP who received IVB injection. The primary outcome measure was the time to complete retinal vascularization, defined as the number of weeks from the IVB injection to the point when vascularization extended to the ora serrata.</p><p><strong>Results: </strong>The study population comprised 155 (49.7%) female and 157 (50.3%) male neonates. The average gestational age at birth was 28.83 weeks (±2.228), and the average birth weight was 1244.90 g (±406.291). The mean duration of hospitalization in the neonatal intensive care unit was 33.71 days (±18.193). The mean (standard deviation) age and weight at complete retinal vascularization were 60.92 (15.16) weeks and 6064.01 (1616.87) g, respectively. The mean time interval between IVB injection and complete retinal vascularization was 24.31 (13.64) weeks. Survival analysis revealed that infants born before 30 weeks or weighing <1500 g experienced longer durations to full vascularization (<i>P</i> < 0.001). In multivariate Cox regression analysis, none of the variables were identified as independent risk factors for the time to complete vascularization.</p><p><strong>Conclusions: </strong>This study investigated the duration required for complete retinal vascularization in infants with ROP who received IVB injections. In addition, it evaluated the influences of birth weight, age, and gender as critical factors affecting the time to complete vascularization.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"328-334"},"PeriodicalIF":0.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Governing Self-Directed Adoption of New Ophthalmic Procedures.","authors":"Henry Bair","doi":"10.4103/joco.joco_299_25","DOIUrl":"https://doi.org/10.4103/joco.joco_299_25","url":null,"abstract":"","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"378"},"PeriodicalIF":0.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Surgical Method: Complete Posterior Vitreous Detachment Induction in Pediatric Patients during Vitrectomy using Perfluorocarbon Liquid and Forceps.","authors":"Fatemeh Bazvand, Mohammadreza Mehrabi Bahar","doi":"10.4103/joco.joco_223_25","DOIUrl":"https://doi.org/10.4103/joco.joco_223_25","url":null,"abstract":"<p><strong>Purpose: </strong>To introduce a modified induction method for complete posterior vitreous detachment (PVD) in pediatric vitrectomy using perfluorocarbon liquids (PFCLs) and forceps.</p><p><strong>Methods: </strong>This is a case series of a new method to induce PVD in pediatric patients. After an unsuccessful attempt at PVD induction, triamcinolone was used to stain the vitreous, small drops of PFCL were injected, and the vitreous stalk was pinched and grasped at the optic nerve head (ONH). After successful induction of vitreous detachment from ONH, more PFCL was added in increments of approximately two-disc diameters each time to progressively extend the PVD toward the vitreous base using forceps until complete detachment was achieved.</p><p><strong>Results: </strong>Successful PVD induction was achieved in three patients undergoing pars plana vitrectomy. A 40-day-old infant was referred due to rhegmatogenous retinal detachment (RRD) with a giant retinal tear after a lensectomy. Furthermore, a 3-year-old boy with RRD, pathologic myopia, and mature cataract underwent PVD induction using the method described above. The last case was a 7-year-old girl with old RRD, macular coloboma, and mature cataract.</p><p><strong>Conclusions: </strong>This technique represents an initial feasibility report suggesting that PFCL-assisted forceps induction may be a practical and accessible method for PVD induction in pediatric vitrectomy. The findings remain preliminary and require validation in a larger series of patients.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"368-370"},"PeriodicalIF":0.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexible Personalized Occlusion Therapy: A New Approach to Enhance Compliance and Efficacy in Amblyopia Treatment in Morocco.","authors":"Mustapha Jaouhari, Chaimae El Harrak, Farida Bentayeb, Youssef El Merabet","doi":"10.4103/joco.joco_90_25","DOIUrl":"https://doi.org/10.4103/joco.joco_90_25","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effectiveness of flexible personalized occlusion therapy compared to standard personalized and fixed occlusion strategies in improving visual acuity in children with amblyopia. It also seeks to analyze the impact of treatment flexibility on patient adherence and total effective dose (TED).</p><p><strong>Methods: </strong>A total of 90 children with amblyopia participated in this prospective study. Participants were divided into three groups: Flexible personalized occlusion, standard personalized occlusion, and standard fixed occlusion. Visual acuity was assessed at baseline and monitored monthly for 12 weeks. Treatment adherence was measured using TED. Statistical analyses included one-way analysis of variance (ANOVA) and repeated-measures ANOVA to compare visual acuity improvements among groups.</p><p><strong>Results: </strong>Baseline visual acuity was comparable across groups (<i>P</i> > 0.05). By the final assessment, the Flexible Personalized Occlusion and Standard Personalized Occlusion groups achieved similar visual acuity improvements (0.2 ± 0.05 logMAR and 0.2 ± 0.04 logMAR, respectively), whereas the Standard Fixed Occlusion group had a slightly smaller improvement, reaching 0.25 ± 0.09 logMAR. The flexible group exhibited the lowest TED (295.4 ± 56 h), suggesting higher efficiency in treatment delivery.</p><p><strong>Conclusions: </strong>Flexible personalized occlusion therapy demonstrated comparable efficacy to standard occlusion strategies while offering greater flexibility and potentially enhancing patient engagement. These findings support the adoption of personalized and adaptable occlusion regimens in amblyopia management.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"352-358"},"PeriodicalIF":0.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal Predictors of Visual Outcome and Recurrence in Naïve Myopic Choroidal Neovascularization Patients.","authors":"Leandro Inferrera, Andrea Gaggino, Alessandro Drigo, Rossella Agolini, Davide Caltagirone, Elena Verdimonti, Daniele Tognetto","doi":"10.4103/joco.joco_177_25","DOIUrl":"https://doi.org/10.4103/joco.joco_177_25","url":null,"abstract":"<p><strong>Purpose: </strong>To identify predictive factors for recurrence and to assess variables influencing visual acuity over time.</p><p><strong>Methods: </strong>This retrospective study analyzed 137 eyes of 128 patients with myopic choroidal neovascularization (mCNV) treated with intravitreal antivascular endothelial growth factor injections (ranibizumab or aflibercept) between June 2017 and June 2022, with a minimum 12-month follow-up. The study cohort was divided into two groups: The recurrence (R) group, which included eyes that experienced a recurrence of mCNV activity, and the nonrecurrence (NR) group, which included eyes without recurrence.</p><p><strong>Results: </strong>The R group consisted of 56 eyes, whereas the NR group included 81 eyes. Recurrence was significantly associated with lower baseline best-corrected visual acuity (BCVA) (odds ratio [OR]: 1.95; <i>P</i> = 0.018), higher central foveal thickness (OR: 0.922; <i>P</i> = 0.001), presence of retinal pigment epithelium (RPE) disruption (OR: 2.272; <i>P</i> = 0.022), presence of subretinal fluid (OR: 2.83; <i>P</i> = 0.008), CNV width (OR: 1.1; <i>P</i> = 0.041), and CNV height (OR: 1.3; <i>P</i> = 0.045). In the NR group, final BCVA was significantly influenced by age (<i>P</i> = 0.001), time to first injection (<i>P</i> = 0.021), baseline BCVA (<i>P</i> = 0.001), BCVA after initial therapy (<i>P</i> = 0.001), RPE disruption (<i>P</i> = 0.019), photoreceptor layer disruption (<i>P</i> = 0.048), and lesion thickness (<i>P</i> = 0.033). In the R group, 12-month BCVA correlated with baseline BCVA (<i>P</i> = 0.0019), number of injections (<i>P</i> = 0.08), RPE disruption (<i>P</i> = 0.027), ellipsoid zone disruption (<i>P</i> = 0.046), and CNV height (<i>P</i> = 0.084).</p><p><strong>Conclusions: </strong>Baseline clinical and imaging biomarkers are significantly associated with both recurrence risk and visual outcomes in mCNV. Early identification of these predictive factors may guide treatment strategies and optimize long-term visual prognosis.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"339-345"},"PeriodicalIF":0.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case Report of Central Retinal Artery Occlusion in a Young Female Post-Fontan Procedure: Clinical Implications and Management.","authors":"Hanan Khalid Aljaidi, Marah Saud AlEnezi, Ghaida Ali Al Ghamdi, Souda E El Sheikh","doi":"10.4103/joco.joco_272_24","DOIUrl":"https://doi.org/10.4103/joco.joco_272_24","url":null,"abstract":"<p><strong>Purpose: </strong>To highlight the importance of recognizing the risk factors for central retinal artery occlusion (CRAO) in patients with congenital heart diseases, as CRAO is a rare but severe condition that can lead to permanent vision loss. Patients with a history of surgical procedures for congenital heart defects, such as the Fontan procedure, may have unique risk profiles for retinal vascular events.</p><p><strong>Methods: </strong>We present the case of a young female patient with a past medical history of a Fontan procedure who experienced acute vision loss in her left eye.</p><p><strong>Results: </strong>The onset was sudden, with no preceding symptoms. Ophthalmologic evaluation and imaging confirmed the diagnosis of CRAO. Further investigations suggested that her underlying cardiovascular condition may have contributed to the vascular event.</p><p><strong>Conclusions: </strong>This case highlights the importance of recognizing the risk factors for CRAO in patients with congenital heart disease, particularly those who have undergone the Fontan procedure. Early detection and management are critical to improving visual outcomes in such patients.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"371-374"},"PeriodicalIF":0.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Topical Tacrolimus as Adjunct Therapy to Corticosteroid in a High-Risk Penetrating Keratoplasty: A Systematic Review and Meta-Analysis.","authors":"Muhammad Shafiq Advani, Syska Widyawati","doi":"10.4103/joco.joco_75_25","DOIUrl":"https://doi.org/10.4103/joco.joco_75_25","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the use of topical tacrolimus as an adjunct therapy to corticosteroids in preventing graft rejection in high-risk penetrating keratoplasty (PKP).</p><p><strong>Methods: </strong>A comprehensive search was conducted through PubMed^®, EMBASE^®, Cochrane Central Register of Controlled Trials, and Google Scholar^® databases from 2000 to 2023. Eligible studies included meta-analysis, systematic review, clinical trial, and case presentations that compared graft rejection rates in high-risk PKP patients treated with corticosteroid versus corticosteroid plus tacrolimus. Studies with a control group using noncorticosteroid therapy were excluded from the study. The study selection process followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Study quality was assessed using Cochrane Risk of Bias 2.0 (RoB 2.0), Newcastle-Ottawa Scale, and RoB for Nonrandomized Intervention Studies.</p><p><strong>Results: </strong>Five studies comprising 298 eyes were included in the study. Rejection rates were found significantly lower in the tacrolimus group (RR: 0.63; 95% confidence interval [CI]: 0.46-0.88; <i>P</i> = 0.006). Tacrolimus also significantly reduced irreversible rejection (RR: 0.50; 95% CI: 0.27-0.93; <i>P</i> = 0.03) and improved visual acuity (RR: 1.45; 95% CI: 1.08-1.93; <i>P</i> = 0.01).</p><p><strong>Conclusions: </strong>Tacrolimus successfully reduces the rejection rate and irreversible rejection in high-risk PKP patients. Improved visual acuity was observed. There were no significant side effects; however, further studies are still needed to achieve more quantitative results, like recommended concentrations.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"271-283"},"PeriodicalIF":0.9,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decoding Cone Morphology in Keratoconus: A Retrospective Study on Contact Lens Selection in Turkish Patients.","authors":"Gül Varan, Serkan Güler, Seda Duran Güler, Burcu Nurözler Tabakçi, Yusuf Yildirim","doi":"10.4103/joco.joco_82_25","DOIUrl":"https://doi.org/10.4103/joco.joco_82_25","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the relationship between cone morphology and the selection of appropriate contact lens types for patients with keratoconus. Specifically, this study aimed to evaluate how keratometry values, cone morphology, and disease severity influence contact lens fitting and visual outcomes. The goal was to optimize contact lens fitting and improve visual rehabilitation for these patients by understanding the correlation between these parameters.</p><p><strong>Methods: </strong>This retrospective study reviewed data from 108 eyes of 73 patients with keratoconus who had undergone corneal cross-linking and had not undergone any prior refractive surgeries. Patient demographics, keratometry values, corneal topography, and keratoconus morphology were recorded, along with the contact lens types prescribed. Keratoconus was classified morphologically (central/nipple, oval, and globus) and graded according to the Amsler-Krumeich system. Statistical analysis was conducted to examine the relationship between disease characteristics and contact lens selection.</p><p><strong>Results: </strong>A total of 108 eyes from 73 patients (mean age: 28.19 ± 8.1 years) were included. Cone morphology was classified as central cone (61.1%), oval cone (32.4%), and globus cone (6.4%). Scleral lenses were the most commonly prescribed (50%), particularly in eyes with advanced keratoconus, such as globus keratoconus and Grade 4 disease. Hybrid and rigid gas permeable (RGP) lenses were commonly prescribed for moderate keratoconus, while toric lenses were most often used for mild cases. Visual acuity improved significantly after lens fitting, with best-corrected visual acuity (logMAR) improving from 0.85 ± 0.38 to 0.07 ± 0.12 (<i>P</i> < 0.0001). This improvement highlights the effectiveness of individualized lens fitting in enhancing visual outcomes.</p><p><strong>Conclusions: </strong>Personalized contact lens selection based on keratometry, cone morphology, and disease severity is crucial for optimizing visual rehabilitation in patients with keratoconus. Scleral lenses are the preferred option for advanced keratoconus, while hybrid and RGP lenses are effective for moderate cases. These findings provide valuable insights for tailoring treatment strategies and improving outcomes in keratoconus management. The study highlights the importance of individualizing lens fitting to achieve better visual outcomes and to guide clinical decisions in the management of keratoconus.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"315-320"},"PeriodicalIF":0.9,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular Biometric Correlations in a Mexican Population: Implications for Intraocular Lens Planning in Anterior Segment Surgery.","authors":"Carlos Antonio Jiménez-Romo, María Guadalupe Martínez-Ruiz, José Felipe Muñoz-Islas, Carlos Ávalos-Gonález, Miriam Guadalupe Becerra-Cota, Ricardo Acosta-Gonález, Jorge Rendón-Félix, Edgar Verduzco-Fernández, Diego Acosta-Peregrina, Arturo Rangel-Beltrán, Valeria Gómez-Márquez","doi":"10.4103/joco.joco_10_25","DOIUrl":"https://doi.org/10.4103/joco.joco_10_25","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the distribution and correlations of ocular biometric parameters in a Mexican population and to assess the differences across axial-length groups.</p><p><strong>Methods: </strong>This is a retrospective, multicentrical, cross-sectional study of healthy eyes examined with IOL Master 700® from 2018 to 2020. Patients were classified into four axial length (AL) groups: short (≤22 mm), normal (>22 mm to <24.50 mm), long (≥24.50 mm to <27.5 mm), and extremely long (≥27.5 mm). Main biometric variables included AL, anterior chamber depth (ACD), lens thickness (LT), central corneal thickness (CCT), corneal diameter (white-to-white [WTW]), pupil diameter, average keratometry (K), and μ-chord.</p><p><strong>Results: </strong>The study included 1622 eyes with a mean age of 57 years. Mean biometric values were AL 23.61 mm, ACD 3.21 mm, LT 4.32 mm, CCT 542 μm, WTW 12 mm, K 43.66 D, and μ-chord 0.40 mm. AL group distribution was short 5.9%, normal 67.2%, long 21.8%, and extremely long 5.1%. Strong correlations were observed between age and LT (<i>r</i> = 0.65, <i>P</i> < 0.001), ACD and LT (<i>r</i> = 0.64, <i>P</i> < 0.001), and AL and ACD (<i>r</i> = 0.50, <i>P</i> < 0.001). μ-chord values decreased progressively as AL increased, showing statistically significant differences among AL groups.</p><p><strong>Conclusions: </strong>Biometric parameters varied systematically across AL categories in a large Mexican cohort. LT increased with age and inversely correlated with ACD, whereas AL correlated positively with ACD and negatively with keratometry. These findings have direct implications for intraocular lens power calculation and risk assessment in cataract and refractive surgery.</p>","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"310-314"},"PeriodicalIF":0.9,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}