{"title":"Integrating artificial intelligence (S-Detect software) and contrast-enhanced ultrasound for enhanced diagnosis of thyroid nodules: A comprehensive evaluation study.","authors":"Lu-Lu Zou, Qi Zhang, Zhi Yao, Yong He, Jun Zhou","doi":"10.1002/jcu.23810","DOIUrl":"10.1002/jcu.23810","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to assess the diagnostic efficacy of Korean Thyroid imaging reporting and data system (K-TIRADS), S-Detect software and contrast-enhanced ultrasound (CEUS) when employed individually, as well as their combined application, for the evaluation of thyroid nodules, with the objective of identifying the optimal method for diagnosing thyroid nodules.</p><p><strong>Methods: </strong>Two hundred and sixty eight cases pathologically proven of thyroid nodules were retrospectively enrolled. Each nodule was classified according to K-TIRADS. S-Detect software was utilized for intelligent analysis. CEUS was employed to acquire contrast-enhanced features.</p><p><strong>Results: </strong>The area under curve (AUC) values for diagnosing benign and malignant thyroid nodules using K-TIRADS alone, S-Detect software alone, CEUS alone, the combined application of K-TIRADS and CEUS, the combined application of S-Detect software and CEUS were 0.668, 0.668, 0.719, 0.741, and 0.759, respectively (p < 0.001). The sensitivity rate of S-Detect software was 89.9% (p < 0.001). It was the highest of the five diagnostic methods above.</p><p><strong>Conclusion: </strong>The utilization of S-Detect software can be served as a powerful tool for early screening. Notably, the combined utilization of S-Detect software with CEUS demonstrates superior diagnostic performance compared to employing K-TIRADS, S-Detect software, CEUS used individually, as well as the combined application of K-TIRADS with CEUS.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Talita Micheletti, Pedro Teixeira Castro, Edward Araujo Júnior, Marco Aurélio Castellano, Cristiano Feijó Andrade, Heron Werner
{"title":"Fetal cervical sarcoma: Comparison between virtual and real fetal bronchoscopy.","authors":"Talita Micheletti, Pedro Teixeira Castro, Edward Araujo Júnior, Marco Aurélio Castellano, Cristiano Feijó Andrade, Heron Werner","doi":"10.1002/jcu.23806","DOIUrl":"10.1002/jcu.23806","url":null,"abstract":"<p><p>Fetal cervical tumors are a life-threatening condition if proper diagnosis and perinatal care are inadequate. The most common causes of fetal cervical masses are teratomas and lymphangiomas. Less common tumors may obstruct the fetal airway due to cervical compression. In this case report, a fetus with a cervical sarcoma was evaluated by ultrasound and MRI. The prenatal imaging characteristics of the tumor were described, virtual navigation of the fetal airway was performed and compared with fetal bronchoscopy to evaluate the consistency of the tumor. Neonatal outcome was also described.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142046683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuf Dal, Fatih Akkuş, Şebnem Karagün, Ahmet Zeki Nessar, Sefanur Gamze Karaca, Mürşide Çevikoğlu Kıllı, Ayhan Coşkun
{"title":"Fetal epicardial fat thickness and modified myocardial performance index in late-onset fetal growth restriction.","authors":"Yusuf Dal, Fatih Akkuş, Şebnem Karagün, Ahmet Zeki Nessar, Sefanur Gamze Karaca, Mürşide Çevikoğlu Kıllı, Ayhan Coşkun","doi":"10.1002/jcu.23804","DOIUrl":"10.1002/jcu.23804","url":null,"abstract":"<p><strong>Aim: </strong>In our study, we aimed to investigate the value of fetal epicardial fat thickness (EFT) and modified myocardial performance index (mod-MPI) in fetal growth restriction (FGR) that develops after the 32nd week of gestation.</p><p><strong>Materials and methods: </strong>Fifty-six pregnant women who met the inclusion and exclusion criteria were included in the study and were divided into two groups: pregnancies diagnosed with FGR after the 32nd week of gestation (FGR group) and those without (control group). Demographic and obstetric histories, ultrasonographic and clinical characteristics, fetal EFT and mod-MPI values, and neonatal outcomes of the groups were recorded, and comparisons were made between the groups. Additionally, the diagnostic performance of fetal EFT value in late FGR was investigated.</p><p><strong>Results: </strong>The FGR group had fetal EFT that was statistically significantly lower (1.11 ± 0.21 vs. 1.34 ± 0.23, p = 0.001). The FGR group had a significantly lower isovolumetric contraction time (ICT) (31.04 ± 6.88 vs. 35.14 ± 7.58, p = 0.048). The two groups' isovolumetric relaxation time (IRT), ejection time (ET), and mod-MPI values (p values 0.871, 0.55, and 0.750, respectively) were comparable. Receiver operating characteristic (ROC) analysis at a cutoff of 1.2 revealed 76.1% sensitivity and 74.2% specificity, respectively, for the diagnostic performance of the fetal EFT value in late-onset FGR. There was a positive predictive value (PPV) and negative predictive value (NPV) of 64.0% and 83.8%, respectively.</p><p><strong>Conclusion: </strong>We found that fetal EFT was significantly lower in FGR and may be useful in diagnosing FGR. However, we observed that mode-MPI did not change in FGR.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A deep unenhanced area on contrast-enhanced ultrasound suggests T2 gallbladder carcinoma.","authors":"Taketoshi Fujimoto, Yo Kato","doi":"10.1002/jcu.23789","DOIUrl":"10.1002/jcu.23789","url":null,"abstract":"<p><p>CE-US (Advanced Dynamic Flow, mechanical index: 1.6) in the perfusion phase (48 s after injection of Sonazoid®, marked with a red underline): A heterogeneously enhanced, sessile elevated lesion with a clearly visible deep unenhanced area (arrowhead), 3 mm in diameter, at the fundus.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echo-planar DWI variants: A comparative study in vertebral marrow pathology.","authors":"Sevcihan Kesen, Nil Tokgöz","doi":"10.1002/jcu.23779","DOIUrl":"10.1002/jcu.23779","url":null,"abstract":"<p><strong>Purpose: </strong>Single-shot echo-planar imaging (ss-EPI) has limited application in vertebral column imaging due to numerous artifacts. Therefore, we aimed to compare readout-segmented echo-planar imaging (rs-EPI) to ss-EPI and assess its value in the differential diagnosis of vertebral infectious, tumoral infiltrative, and degenerative disorders.</p><p><strong>Materials and methods: </strong>Sixty-six adult patients with spondylodiscitis (SD, n = 26), tumoral infiltration (TI, n = 20), or Modic type I degeneration (DE, n = 20) findings on spinal magnetic resonance imaging (MRI) included in this retrospective study. Two radiologists scored images for quality on a 4-point scale (image resolution, degree of geometric distortion, lesion selectivity, and diagnostic reliability) and measured signal intensity (SI), apparent diffusion coefficient (ADC), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). DE and SD groups also united to form the benign group.</p><p><strong>Results: </strong>In all groups, rs-EPI performed better than ss-EPI in image quality, SNR, and CNR (p < 0.05). The difference between mean pathological ADC (ADC<sub>P</sub>) in the two sequences was statistically significant (p < 0.05). There was no significant difference between the groups in terms of ADC<sub>P</sub> in rs-EPI (p = 0.229), unlike ss-EPI (p = .025). Pathological SI (SI<sub>P</sub>) and CNR in rs-EPI were significantly higher in the malignant group than benign group (p = 0.002, p < 0.001). In rs-EPI, no significant difference was found between malignant and benign groups' ADC<sub>P</sub> (p = 0.13).</p><p><strong>Conclusion: </strong>The rs-EPI is a diffusion-weighted imaging (DWI) method with higher image quality that diminishes motion-induced phase errors and increases resolution through phase corrections. However, the distinction of malignant and benign vertebral bone marrow pathologies is unsatisfactory for rs-EPI compared with ss-EPI.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142093213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Na Zhang, Limin Sun, Xing Chen, Hanxing Song, Wenyu Wang, Hui Sun
{"title":"Meta-analysis of contrast-enhanced ultrasound in differential diagnosis of breast adenosis and breast cancer.","authors":"Na Zhang, Limin Sun, Xing Chen, Hanxing Song, Wenyu Wang, Hui Sun","doi":"10.1002/jcu.23803","DOIUrl":"10.1002/jcu.23803","url":null,"abstract":"<p><p>This systematic review and meta-analysis study aimed to determine the total capacity of contrast-enhanced ultrasound (CEUS) in the differential diagnosis of breast lesions and breast cancer. For collecting papers, four groups of keywords were searched in five databases. The required information was extracted from the selected papers. In addition to the descriptive findings, a meta-analysis was also conducted. Thirty-three of thirty-six studies (91.67%) on the differential diagnosis of various degrees and types of breast lesions showed that CEUS has proper performance. The pooled values related to the sensitivity and specificity of CEUS were computed by 88.00 and 76.17.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sukran Dogru, Asli Altinordu Atci, Fatih Akkus, Ali Acar
{"title":"Effect of abnormal placentation on fetal heart function and neonatal outcomes.","authors":"Sukran Dogru, Asli Altinordu Atci, Fatih Akkus, Ali Acar","doi":"10.1002/jcu.23790","DOIUrl":"10.1002/jcu.23790","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the fetal modified (mod)-myocardial performance index (MPI) for fetal cardiac function in placenta percreta (PPC) pregnancies with placenta previa (PP) and assess neonatal outcomes.</p><p><strong>Materials and methods: </strong>This study included 104 pregnant women: 52 with PPC and 52 as the control group. Mod-MPI measurements and neonatal outcomes were evaluated in all cases.</p><p><strong>Results: </strong>The PPC group had a significantly lower left ejection time (p = 0.044) and significantly higher mod-MPI (p = 0.001) than the control group. The optimal mod-MPI predictive cut-off value at the neonatal intensive care unit (NICU) admission in the PPC group was 0.53 with 53.8% specificity and 88.5% sensitivity (p = 0.019). The optimal mod-MPI predictive cut-off value at the 5th APGAR score below 7 in the PPC group was 0.55 with a specificity of 67.7% and a sensitivity of 76.2% (p = 0.016).</p><p><strong>Conclusion: </strong>Fetal MPI was higher in pregnant women with PPC compared to the control group. Among the PPC cases, those with MPI above a certain predictive level showed more frequent NICU admissions and lower APGAR scores.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ileal venous malformation in a pediatric patient.","authors":"Bo Zhang, Hou-Qing Pang, Hong Luo","doi":"10.1002/jcu.23786","DOIUrl":"10.1002/jcu.23786","url":null,"abstract":"<p><p>A 16-month-old girl presented with ileal venous malformation. Ultrasound facilitated a preoperative diagnosis, leading to a successful surgical resection. The study emphasizes the critical role of identifying sonographic features like intestinal wall thickening, a serpiginous mass with sluggish blood sinuses, and rich vascular flow for accurate diagnosis and timely treatment.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141982410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bright and enlarged fetal kidneys: One phenotype different genotypes, and counseling dilemmas.","authors":"Preeti Paliwal, Seema Thakur, Shreyasi Sharma","doi":"10.1002/jcu.23797","DOIUrl":"10.1002/jcu.23797","url":null,"abstract":"<p><strong>Introduction: </strong>In the present study we describe atypical cases with bright and enlarged fetal kidneys identified on fetal ultrasound with different genetic etiologies.</p><p><strong>Methods: </strong>Exome sequencing was undertaken after prenatal counseling and after the initial diagnosis of enlarged fetal kidneys was made on ultrasound for four cases and the results were then correlated.</p><p><strong>Results: </strong>In the present study we identified underlying variants in ACE, ETFA, PKD1, and MKS1 gene where the atypical presentation of fetal kidneys was noted either as a part of spectrum of syndrome or alone.</p><p><strong>Conclusions: </strong>In the era of exome sequencing, targeted gene sequencing is getting replaced and for better. However not all answers are direct, and sometimes the variant categorization is dependent on the acumen and agreement of all those involved in the process. It includes those involved the diagnostic as well those catering to the patients. It is very important to be updated on the relevance of multiple gene in causing similar phenotypes particularly in the prenatal context were coming up with a timely diagnosis is very important for any sort of intervention.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wen-Hua Liu, Lei Yang, Xiao-Yi Wang, Ting-Yi Wang, Guang-Mei Zheng, Yu-Ting Zhu, Shan Che
{"title":"Imaging findings of type I neurofibromatosis with outcome of malignant peripheral nerve sheath tumor in the right lower extremity.","authors":"Wen-Hua Liu, Lei Yang, Xiao-Yi Wang, Ting-Yi Wang, Guang-Mei Zheng, Yu-Ting Zhu, Shan Che","doi":"10.1002/jcu.23807","DOIUrl":"10.1002/jcu.23807","url":null,"abstract":"<p><p>Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder caused by mutations of the NF1 tumor suppressor gene, characterized by café-au-lait spots, neurofibromas, and Lisch nodules. Malignant peripheral nerve sheath tumor (MPNST) is an extremely rare malignancy with neural differentiation potential. The lifetime risk of developing MPNST in NF-1 patients is 8%-13%.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142093214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}