Journal of Clinical Ultrasound最新文献

{"title":"Assessment of Fetal Cardiac Morphology and Function in Pregnant Women With Systemic Lupus Erythematosus Using Speckle Tracking Echocardiography.","authors":"Jian Wu, Yanping Ruan, Hairui Wang, Xiaoyan Gu, Jiancheng Han, Yihua He","doi":"10.1002/jcu.23974","DOIUrl":"https://doi.org/10.1002/jcu.23974","url":null,"abstract":"<p><strong>Purpose: </strong>Study aimed to assess fetal heart morphology and function in pregnancies with systemic lupus erythematosus (SLE) utilizing speckle tracking echocardiography (STE) and to evaluate indicators for predicting fetal subclinical cardiac damage in this population.</p><p><strong>Methods: </strong>The study involved 99 SLE-affected fetuses and 99 gestational age-matched controls. The fetal cardiac morphology and function parameters were calculated using STE (FetalHQ).</p><p><strong>Results: </strong>The absolute values of left ventricular (LV) global longitudinal strain (GLS), right ventricular (RV) GLS, LV fractional area change (FAC), and RV FAC in the SLE group were lower than those in the control group (p < 0.001). The 24-segment fractional shortening (FS) analysis revealed significantly lower FS in the SLE group than the controls for LV segments 11-12 and RV segments 4-24. The 24-segment sphericity index (SI) analysis indicated significantly lower SI in the SLE group than the controls for LV segments 1-24 and RV segments 1-8. The LV GLS (AUC = 0.859) and RV GLS (AUC = 0.841) could be considered good predictors of subclinical myocardial damage in SLE-affected fetuses.</p><p><strong>Conclusions: </strong>STE indicated that fetuses in pregnant women with SLE present cardiac morphology and function that have changed compared to the controls. Further investigations are needed to evaluate STE indices such as the GLS, FAC, and 24-segment FS and SI to predict fetal prognosis in pregnant women with SLE.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Fetal Myocardial Contractility of Pre-Existing Diabetes Mellitus by Three-Dimensional Ultrasonography Using STIC and Vocal Methods.","authors":"Letícia Bucioli Oliveira, Alberto Borges Peixoto, Nathalie Jeanne Bravo-Valenzuela, André Souza Malho, Rosiane Mattar, Edward Araujo Júnior","doi":"10.1002/jcu.23972","DOIUrl":"https://doi.org/10.1002/jcu.23972","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate global and ventricular myocardial contractility in fetuses of pregnant women with pre-existing diabetes compared with normal fetuses using three-dimensional (3D) ultrasound with the Virtual Organ Computer-aided Analysis (VOCAL) and Spatio-temporal Image Correlation (STIC) methods.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was performed on 60 normal fetuses and 20 fetuses from pregnant women with pre-existing diabetes. The STIC and VOCAL methods were used to calculate fetal cardiac volumes. Global contractility was calculated by subtracting cardiac volume in diastole from cardiac volume in systole. Ventricular contractility was calculated by subtracting diastolic ventricular volume from systolic ventricular volume. Myocardial contractility was correlated with gestational age using Spearman's coefficient (r), while the difference between normal and diabetic pregnant women was calculated using Student-t and Mann-Whitney tests.</p><p><strong>Results: </strong>Pregnant women with pre-existing diabetes had a higher mean number of pregnancies than normal pregnant women (2.4 vs. 1.8 pregnancies, p = 0.028). There were no significant differences in global and ventricular contractility between normal fetuses and those of pregnant women with previous diabetes (p = 0.070 and 0.186, respectively). A moderate positive significant correlation was observed between gestational age and global myocardial contractility (r = 0.58, p < 0.0001). There was a strong positive significant correlation between gestational age and ventricular myocardial contractility (r = 0.62, p < 0.0001). A one-week increase in gestational age was responsible for an increase in global and ventricular myocardial contractility of 0.222 and 0.1505 cm³, respectively. Considering only pregnant women with pre-existing diabetes, there was a strong negative significant correlation between glycated hemoglobin levels and global myocardial contractility (r = -0.63, p = 0.027) and a moderate negative significant correlation and ventricular myocardial contractility (r = -0.59, p = 0.044).</p><p><strong>Conclusions: </strong>The global and ventricular myocardial contractility of normal fetuses and fetuses of pre-existing diabetes pregnant women measured by 3D ultrasound using the STIC and VOCAL methods showed a linear and positive correlation with gestational age and no significant differences between them.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal Diagnosis and Prognostic Factors in Fetuses With Arthrogryposis Multiplex Congenita-A Systematic Review.","authors":"Mario Brock Leao, Marianna Facchinetti Brock, Jorge Roberto Di Tommaso Leao, Gianpaolo Grisolia, Mario Lituania, Samantha Erin Neumann, Gabriele Tonni, Rodrigo Ruano","doi":"10.1002/jcu.23983","DOIUrl":"https://doi.org/10.1002/jcu.23983","url":null,"abstract":"<p><p>Arthrogryposis Multiplex Congenita (AMC) is characterized by the presence of multiple joint contractures in the fetus' body. The diagnosis of AMC is complex and often missed prenatally. This comprehensive review of the literature published over the last 20 years, with an emphasis on the role of prenatal ultrasound in predicting postnatal outcomes in a fetus with AMC, showed that ultrasound is a crucial tool to diagnose and prognosticate this rare disease. Different clinical manifestations of AMC are associated with different outcomes. Postnatal prognosis depends on several factors. Future multicenter prospective studies are necessary to investigate the prognostic factors associated with AMC.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contrast-Enhanced Ultrasound Reveals a Rare Pseudo-Malignant Lesion: Intrahepatic Extramedullary Hematopoiesis.","authors":"Ya-Lan Zheng, Xia-Tian Liu, Yuan-Yuan Zheng, Cai-Ye Ma, Fang Liu","doi":"10.1002/jcu.23967","DOIUrl":"https://doi.org/10.1002/jcu.23967","url":null,"abstract":"<p><p>Extramedullary hematopoiesis (EMH) is a rare condition where hematopoietic tissue forms outside the bone marrow. We present a case of a patient with long-standing myelofibrosis and thalassemia, diagnosed with intrahepatic EMH (IEMH) through surgical pathology. This case describes its etiology, pathogenesis, and the causes of misdiagnosis, mainly focusing on the characteristics of contrast-enhanced ultrasound (CEUS) and magnetic resonance imaging (MRI) of IEMH. The MRI manifestations of IEMH are diverse due to differences in the age and activity of the lesions. Notably, it provides the first description of IEMH's enhancement pattern on CEUS, a potential unique imaging feature of this condition.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Rest Improves Fetal Growth in Small-For-Gestational Age and Growth Restricted Fetuses Defined by the Delphi Consensus Protocol.","authors":"Greggory R DeVore, Bardo Polanco","doi":"10.1002/jcu.23980","DOIUrl":"https://doi.org/10.1002/jcu.23980","url":null,"abstract":"<p><strong>Objective: </strong>The objective was to determine if maternal rest in the left lateral recumbent position increases the estimated fetal weight (EFW) in fetuses classified by the Delphi consensus as growth restricted (FGR) or small-for-gestational age (SGA).</p><p><strong>Study design: </strong>This was a retrospective observational study of 265 fetuses classified as FGR or SGA using the Delphi consensus. After the diagnosis of FGR or SGA, the patient was asked to begin resting in the left lateral recumbent position during her waking hours for 2 weeks. The EFW was measured 2 weeks following maternal rest.</p><p><strong>Results: </strong>Of the 265 fetuses, FGR was identified in 56% (148/265) and SGA in 44% (117/265). Following maternal rest, the median values for the EFW percentile were significantly greater than at the time of diagnosis of FGR (18 vs. 5.96) and SGA (19 vs. 7.39). Following maternal rest, the EFW increased from < 10th percentile (100%) to greater than the 10th percentile in 70% of FGR and 82% of SGA fetuses.</p><p><strong>Conclusions: </strong>Fetuses with growth restriction or who were small-for-gestational age significantly increased their weight from below to above the 10th percentile following 2 weeks of maternal rest.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-Frequency Ultrasound and Shear Wave Elastography of Dermatofibrosarcoma Protuberans: A Novel Approach for Early Detection.","authors":"Yan Zhang, Jian-Feng Liang, Ping-Ping Luo, Wang-Zhao Wu, Jing Wang","doi":"10.1002/jcu.23978","DOIUrl":"https://doi.org/10.1002/jcu.23978","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the high-frequency ultrasound (HFUS) and shear wave elastography (SWE) features of dermatofibrosarcoma protuberans (DFSP) to enhance early diagnosis and improve clinical outcomes.</p><p><strong>Methods: </strong>A retrospective cohort analysis was conducted with histopathologically confirmed DFSP, utilizing HFUS and SWE imaging data.</p><p><strong>Results: </strong>Sixteen patients (10 males, 6 females; mean age 43 ± 11 years) with histopathologically confirmed DFSP were studied. The lesions were predominantly located on the trunk (56.25%), with a mean maximum diameter of 33.41 ± 16.17 mm and a maximum thickness of 14.49 ± 7.48 mm. Most lesions presented with elliptical (43.75%) or lobulated (37.50%) configurations. Sonographically, 81.75% showed a mixed hypoechoic-hyperechoic echo pattern with peripheral hyperechoic regions in 75% of cases. All lesions involved both dermal and subcutaneous tissue, with 43.75% showing finger-like projections. All lesions demonstrated vascularity on color Doppler, predominantly Grade 2 (62.5%). On SWE, the average Young's modulus was 38.68 ± 19.43 kPa, and 93.75% of lesions exhibited a characteristic \"stiffer superficial cap\" sign.</p><p><strong>Conclusions: </strong>DFSP exhibits distinctive sonographic features including mixed echo patterns, peripheral hyperechoic regions, and finger-like projections. The newly identified \"stiffer superficial cap\" sign on SWE, combined with HFUS features, may improve the clinical suspicion of DFSP, potentially expediting biopsy decisions and definitive diagnosis.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Findings of Incarcerated Hernia in the Inguinal Region Complicated by Bowel Rupture: A Case Report.","authors":"Haiying Liu, Min Han","doi":"10.1002/jcu.23982","DOIUrl":"https://doi.org/10.1002/jcu.23982","url":null,"abstract":"<p><p>Ultrasound is a non-invasive, non-ionizing radiation imaging modality for soft tissues. An incarcerated hernia occurring in the inguinal region accompanied by intestinal rupture can be a challenging clinical diagnosis, and ultrasound, with its excellent imaging capabilities, is more effective in identifying the underlying cause. Here, we report a clinical case demonstrating how ultrasound identified an incarcerated hernia in the inguinal region accompanied by intestinal rupture, despite atypical symptoms, and helped determine the indication for emergency surgery, which was promptly performed to prevent further complications.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research of Ultrasonic Shear Wave Elastography in Evaluating the Efficiency of Neoadjuvant Chemotherapy for Breast Cancer.","authors":"Jingjing Luo, Yunen Lin, Ziyou Zeng, Haiyun Deng, Tao Li","doi":"10.1002/jcu.23951","DOIUrl":"https://doi.org/10.1002/jcu.23951","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to identify reliable quantitative parameters of ultrasonic shear wave elastography (SWE) that demonstrate advantages in assessing the efficacy of neoadjuvant chemotherapy (NAC) for breast cancer by comparison to conventional ultrasound (US). This research also analyzed the associations between SWE parameters and tumor collagen fibers from post-NAC breast cancer lesions to explore the histological micro-mechanisms of stiffness change for breast cancer after NAC.</p><p><strong>Methods: </strong>Forty-Seven breast cancer lesions examined with US and SWE were eligible for enrollment from January 2021 to July 2023. The ultrasonic maximum diameter (D_max), mean elastic value (E_mean), maximum elastic value (E_max), and minimum elastic value (E_min) before and after NAC were determined. Receiver operating characteristic (ROC) curves were drawn to compare the diagnostic efficacy regarding the change rates of the above parameters. Additionally, correlation analyses were performed to examine the relationship between effective SWE quantitative parameters and collagen fibers after NAC.</p><p><strong>Results: </strong>Among the 47 breast cancer lesions, 24 lesions showed significant pathological responses, while the other 23 lesions exhibited that the pathological responses were nonsignificant. The area under the curve (AUC) of ΔE_min was the lowest (ΔE_min:0.466, ΔD_max: 0.679, ΔE_max: 0.803, and ΔE_mean: 0.813). The collagen fiber category showed a significant positive correlation with E_mean (r = 0.711) and E_max (r = 0.669) after NAC. However, the collagen fiber content demonstrated no significant correlation with E_mean or E_max (p > 0.05).</p><p><strong>Conclusion: </strong>D_max, E_mean, and E_max are valuable parameters for evaluating NAC efficacy, while Emin is not reliable. E_mean and E_max demonstrate similar efficacy, both superior to D_max. The stiffness of post-NAC breast cancer lesions is predominantly related to the category of collagen fibers rather than their content.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Value of Ultrasound and Contrast-Enhanced Ultrasound in a Young Asymptomatic Patient With Duodenal Neuroendocrine Neoplasms: A Case Report.","authors":"Huiyu Yang, Lin Zhao, Xiang Jing, Yanmin Kan","doi":"10.1002/jcu.23957","DOIUrl":"https://doi.org/10.1002/jcu.23957","url":null,"abstract":"<p><p>Conventional ultrasound(US) plays an important role in check-up, while contrast-enhanced ultrasound(CEUS) is a valuable tool for distinguishing tumor characteristics and guiding subsequent diagnosis and treatment. We present a rare case of duodenal neuroendocrine neoplasms (NENs) with liver metastasis in a young male, whose liver masses were detected by US during a check-up and then subsequently underwent Sonazoid-CEUS examination in the outpatient department. The lesions in the liver showed rapid hyper-enhancement in the arterial phase followed by early washout in the portal venous phase, finally showing a defect in the Kupffer phase, which strongly suggested metastases. The patient was promptly admitted for further examination, leading to a timely diagnosis of duodenal NENs with liver metastasis. This case highlights the importance of US and CEUS in asymptomatic liver masses in young patients.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Title: Shear Wave Elastography (SWE) of Hamstring Muscles and Outcome Measures in Rheumatology (OMERACT) Knee Osteoarthritis Ultrasound Scores in Patients With Knee Osteoarthritis With MRI Association: A Cross Sectional Observational Study.","authors":"Priyam Jain, Shruti Chandak, Subhasish Panda, Ankur Malhotra, Subhashree Dash, Umme Afifa, Arjit Agarwal","doi":"10.1002/jcu.23953","DOIUrl":"https://doi.org/10.1002/jcu.23953","url":null,"abstract":"<p><strong>Background: </strong>The Outcome Measures in Rheumatology (OMERACT) and MRI Osteoarthritis Knee Score (MOAKS) scores are semi-quantitative scores used in the evaluation knee osteoarthritis (KOA) by ultrasonography (US) and MRI. Assessment of hamstring muscle function, which is very important for the prognosis and rehabilitation of KOA patients, can be attempted by shear wave elastography (SWE).</p><p><strong>Aim: </strong>To study the SWE of hamstring muscles and OMERACT US scores in patients with KOA and compare them with MOAKS scores.</p><p><strong>Method: </strong>This prospective, observational study was done on 80 patients with KOA who underwent MRI, US, and SWE examinations with calculation of MOAKS and OMERACT scores, as well as VTI and VTIQ assessment of hamstrings. Comparison of the findings of these was done, and appropriate statistical tests were applied.</p><p><strong>Result: </strong>Statistically significant associations were found between OMERACT and MOAKS using Spearman Rho correlation for osteophytes (0.816 with p value 0.001), meniscal extrusion (0.514 with p value 0.001), cartilage abnormalities (0.442 with p value 0.001), joint effusion (0.397 with p value 0.001) and synovitis (0.34 with p value 0.002). The stiffness of hamstring muscles on SWE were also significantly correlated with MOAKS and OMERACT scores with p value of < 0.05 and 0.014, respectively. Color coding and stiffness on VTIQ of hamstring muscles were also significantly associated with BML size (p value 0.001), cartilage abnormalities (p value 0.001), osteophytes (p value 0.001), synovitis (p value 0.05), and meniscal extrusion (p value 0.001) found on MRI.</p><p><strong>Conclusion: </strong>US of knee with SWE of hamstrings can be used not only as a primary screening modality for KOA but also for proper rehabilitation and management of these patients.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}