Journal of Clinical Ultrasound最新文献

{"title":"Appraisal in Spinal Stenosis due to Heterotopic Ossification in Hyperparathyroidism.","authors":"Ilker Sengul, Demet Sengul","doi":"10.1002/jcu.70116","DOIUrl":"https://doi.org/10.1002/jcu.70116","url":null,"abstract":"","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation Into the Utility of 3D Speckle-Tracking Echocardiography in Detecting Coronary Artery Microcirculation Dysfunction in Ischemia With Non-Obstructive Coronary Artery Disease.","authors":"Yuexia Ma, Lina Guan, Xiaohong Li, Jianqiang Zhang, Xiaomei Li, Yuming Mu","doi":"10.1002/jcu.70108","DOIUrl":"https://doi.org/10.1002/jcu.70108","url":null,"abstract":"<p><strong>Aim: </strong>To assess the utility of three-dimensional speckle-tracking echocardiography (3D-STE) in detecting coronary artery microcirculation dysfunction (CMCD) with non-obstructive coronary artery (INOCA) disease.</p><p><strong>Materials and methods: </strong>Twenty-one patients diagnosed with INOCA were enrolled and underwent echocardiography and [¹⁸F]fluorodeoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG PET/CT) myocardial metabolic imaging, which is used as the gold standard for diagnosing CMCD. Further, a total of 357 myocardial segments across these 21 participants were categorized into the control group and the CMCD group according to the results of [¹⁸F]FDG PET/CT. Subsequently, 2D regional systolic peak longitudinal strain (2D-RLS), 2D regional systolic peak circumferential strain (2D-RCS), regional systolic peak 3D main strain (R3D strain), longitudinal strain (3D-RLS), circumferential strain (3D-RCS), and radial strain (3D-RRS) of the left ventricle were assessed. At last, the receiver operating characteristic (ROC) curves of 3D-STE parameters were calculated to evaluate the diagnostic value of 3D-STE for CMCD.</p><p><strong>Results: </strong>The absolute value of total R3D strain is decreased in the CMCD group (p < 0.05). In addition, R3D and 3D-RLS in the CMCD group exhibited a significant reduction in the basal, middle, and apical segments compared to the control group (p < 0.05). No difference was observed in 2D strain parameters between the CMCD group and the control group. Among all strain parameters, the R3D strain in the apical segments had the highest diagnostic efficacy, with an optimal cutoff of -41.5 (sensitivity, 88.4%; specificity, 80.5%).</p><p><strong>Conclusion: </strong>Our findings indicate that the 3D-STE could serve as an advantageous diagnostic instrument for discriminating individuals with CMCD.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thoracic Ultrasound-Related Management Change: Predictors and the Role of Operator Certification (Secondary Analysis of UltraMAN).","authors":"Jorge E Lopez Matta, Micah L A Heldeweg, Luigi Pisani, Carlos V Elzo Kraemer, Stefanie Slot, Mark E Haaksma, Jasper M Smit, Amne Mousa, Giovanna Magnesa, Fabrizia Massaro, Hugo R W Touw, Viviane Schouten, Pieter R Tuinman, David J van Westerloo","doi":"10.1002/jcu.70104","DOIUrl":"https://doi.org/10.1002/jcu.70104","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate which patient characteristics, ultrasound operator certification level, and thoracic ultrasound (TUS) examination findings are associated with a TUS-induced change in clinical management in adult intensive care unit (ICU) patients.</p><p><strong>Design: </strong>Post hoc analysis of a prospective international observational study (UltraMan study) on the impact of thoracic ultrasound on clinical management of critically ill patients. The first TUS examinations of each patient included in the study were included in this analysis. Multivariable logistic regression was performed to identify which patient characteristic(s), operator certification level, or TUS-related factors were significantly associated with a change in management.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements and main results: </strong>The first TUS examinations of each of the 534 patients were included in this analysis. TUS led to management changes in almost half of the patients in whom a TUS was performed (44.6%). TUS-induced management changes were significantly associated with patient characteristics. Specifically, a medical history of cardiovascular disease demonstrated a significant association (OR: 1.73; 95% CI: 1.12-2.68). In terms of TUS examination findings, hypovolemia demonstrated a significant association with a change in management (OR: 2.05; 95% CI: 1.10-3.80). No significant association was found between ultrasound operator certification level and changes in management driven by TUS.</p><p><strong>Conclusions: </strong>This study indicates that TUS was associated with management changes in 44.6% of ICU patients, with stronger associations in those with cardiovascular disease and hypovolemia, and no detectable effect of operator certification in adjusted analyses. As a post hoc analysis of an observational cohort, these findings warrant cautious interpretation and underscore the importance of competency-based training and quality assurance.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trans-Fistula Contrast-Enhanced Ultrasound in Diagnosing a Complex Anal-Bartholin-Perineal Fistula of Crohn's Disease: A Case Report.","authors":"Dilimire Abuliezi, Yuan Luo, Qin Huang, Yin Yang, Hua Zhuang","doi":"10.1002/jcu.70111","DOIUrl":"https://doi.org/10.1002/jcu.70111","url":null,"abstract":"<p><p>This case report presents an uncommon presentation of Crohn's disease (CD) complicated by an anal-Bartholin-perineal fistula. Notably, ultrasound was the initial imaging modality to demonstrate suspicious fistulous tract features in this case. Definitively, trans-fistula contrast-enhanced ultrasound (TF-CEUS) clearly visualized the fistula, providing real-time dynamic architectural details that were critical for diagnosis. TF-CEUS emerged as a valuable diagnostic adjunct in this case, offering novel insights into evaluating complex perianal fistulous disorders in CD, particularly when conventional imaging modalities like MRI yield inconclusive results.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extracranial Internal Carotid Artery Doppler Ultrasound Imaging Findings in Kuwaiti Children With Sickle Cell Disease and Without Neurological Symptoms.","authors":"Adekunle Adekile, Saad A Asbeutah, Akram M Asbeutah","doi":"10.1002/jcu.70093","DOIUrl":"https://doi.org/10.1002/jcu.70093","url":null,"abstract":"<p><strong>Purpose: </strong>The time-averaged mean of the maximum velocity (TAMMV) in both intracranialinternal carotid artery (iICA) and extracranial (eICA) and hematological variables in sickle cell disease (SCD) patients was investigated.</p><p><strong>Methods: </strong>Transcranial Doppler Imaging (TCDI) was performed with a 1-3 MHz phased-array and Linear 3.3-10 MHz transducers for both ICA. Patients were divided into three groups according to age and genotype. Blood parameters were determined using routine methods. ANOVA and linear regression analyses were done.</p><p><strong>Results: </strong>There were 59 patients, 24 males and 35 females (26 with HbSS, 29 HbSβ⁰, and 4 with HbSD). The average age ± SD for all patients was 10.8 ± 3.2 years. The average ± SD TAMMV for iICA was 72.4 ± 11.3 and for eICA was 63.4 ± 25.8 cm/s. There were no significant differences among patients with different genotypes. The iICA and eICA TMMAV according to age (average ± SD) for all were 72.4 ± 11.3 for iICA and 63.4 ± 25.8 for eICA. Age, platelet count, neutrophil count, LDH, and bilirubin showed no significant correlation with TAMMV in the iICA; however, it was significant in the eICA (p < 0.05).</p><p><strong>Conclusion: </strong>A significant correlation was found between age and markers of SCD severity and TAMMV in the eICA, but not with iICA. Therefore, the former might be a more important indicator of vasculopathy in our patients.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Shear Wave Elastography and Superb Microvascular Imaging Be Used as Alternative Methods to Scintigraphy in the Evaluation of Renal Parenchymal Damage in Pediatric Patients With Vesicoureteral Reflux?","authors":"Gülşah Burgazdere, Derya Karabulut, Burak Günay, Fethi Emre Ustabaşıoğlu, Nermin Tunçbilek","doi":"10.1002/jcu.70105","DOIUrl":"https://doi.org/10.1002/jcu.70105","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the diagnostic utility of elasticity with shear wave elastography (SWE) technique and microvascularization with super microvascular imaging (SMI) technique in renal parenchymal scar areas developing as a result of vesicoureteral reflux (VUR) and to compare the effectiveness of these two methods in detecting damage in the renal parenchyma with the results of dimercaptosuccinic acid (DMSA) scintigraphy.</p><p><strong>Materials and methods: </strong>Between July 2022 and July 2023, 40 patients diagnosed with VUR by voiding cystourethrogram (VCUG) and 31 patients in the control group were included in this prospective, unicenter study. The vascularity characteristics of all kidneys and the parenchymal stiffness levels were examined respectively with superb microvascular imaging and SWE by two independent radiologists.</p><p><strong>Results: </strong>A statistically significant difference was found between the mean SWE and SMI values of normal renal parenchyma and renal scar tissue (p < 0.05). The mean SWE and SMI values of kidneys with scar tissue were found to be statistically higher than those of kidneys with VUR but without scar tissue (p < 0.05). Also, a relationship was found between the duration of VUR exposure and the formation of scar tissue in the kidneys. The sensitivity and specificity values for predicting the presence of scar tissue in the kidneys were determined as 73.7% and 70.5% with the SMI method, and 89.5% and 67.2% with the SWE method, respectively.</p><p><strong>Conclusion: </strong>SWE and SMI techniques can be considered as complementary alternative methods in the follow-up of pediatric patients with VUR in whom scar tissue is detected in the kidneys with DMSA, as they are inexpensive, radiation-free, and useful methods for the detection and evaluation of scar tissue.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shear Wave Elastography-Based Quantitative Assessment of Carotid Artery Elasticity in Uremic Patients With Different Left Ventricular Configurations.","authors":"Xinyao Wang, Dongmei Huang, Hongyan Cui","doi":"10.1002/jcu.70110","DOIUrl":"https://doi.org/10.1002/jcu.70110","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the potential clinical value of shear wave elastography (SWE) for quantitatively assessing carotid artery elasticity in uremic patients with different left ventricular configurations.</p><p><strong>Methods: </strong>According to different left ventricular configurations, 133 patients diagnosed with uremia were divided into four groups: group B (normal configuration, NG, n = 37), group C (centripetal remodeling, CR, n = 37), group D (centripetal hypertrophy, CH, n = 38), and group E (eccentric hypertrophy, EH, n = 21). Additionally, a control group (group A) consisting of 40 healthy volunteers was selected. None of the subjects exhibited plaque formation in their carotid arteries. Conventional carotid ultrasound was used to assess the intima-media thickness (IMT), peak systolic velocity (PSV), and the systolic and diastolic diameters (Ds and Dd) of the left common carotid artery. Moreover, the wall motion degrees (ΔD) and arterial stiffness coefficient (β) were calculated. The maximum elastic modulus (MEmax), mean elastic modulus (MEmean), and minimum elastic modulus (MEmin) of the carotid artery anterior wall intima-media were obtained using SWE.</p><p><strong>Results: </strong>Compared with group A, the IMT and β values in groups B and C were increased; however, the differences among the three groups were not statistically significant (p > 0.05). In contrast, groups D and E exhibited markedly elevated IMT and β values, which were significantly different from those in groups A, B, and C (p < 0.05). Groups B through E exhibited significantly elevated MEmax, MEmean, and MEmin values in comparison to group A. Statistically significant intergroup differences were identified (p < 0.05), reflecting a stepwise increase in the order of E > D > C > B > A. The linear regression analysis revealed a statistically significant association between different left ventricular configurations and SWE parameters in patients with uremia (p < 0.05).</p><p><strong>Conclusion: </strong>SWE can quantitatively assess carotid artery elasticity in uremic patients with different left ventricular configurations.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Multimodal Ultrasound Combined With BI-RADS in Classification and Diagnosis of Non-Mass Breast Lesions.","authors":"Zengdi Yang, Yongyan Lyu, Yanting Yang, Cuiping Xu, Keke Zhang, Xuxu Yang, Feng Chen, Lanlan Cheng, Minglei Ren","doi":"10.1002/jcu.70115","DOIUrl":"https://doi.org/10.1002/jcu.70115","url":null,"abstract":"<p><strong>Introduction: </strong>The primary objective of this study is to assess the diagnostic accuracy of multimodal ultrasound, including microvascular flow imaging (MVFI), shear wave elastography (SWE), and contrast-enhanced ultrasound (CEUS), in conjunction with the breast imaging reporting and data system (BI-RADS) for non-mass breast lesions (NMLs).</p><p><strong>Methods: </strong>A total of 100 patients who received treatment in our hospital from April 2021 to June 2024 were retrospectively collected. All patients had complete pre-operative ultrasound BI-RADS, MVFI, SWE, and CEUS. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated; the diagnostic efficacy of the methods was compared, and the diagnostic performance of the subjects was plotted.</p><p><strong>Results: </strong>The agreement between the BI-RADS-MVFI-SWE-CEUS alone and the pathological results was very high, with a Kappa value of 0.806. The area under the curve (AUC) of the combined diagnosis of MVFI-SWE-CEUS and BI-RADS-MVFI-SWE-CEUS was 0.885 (p < 0.001) and 0.922 (p < 0.001). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of BI-RADS-MVFI-SWE-CEUS for the diagnosis of NMLs were higher than those of the diagnosis alone (p < 0.05), with 95.24%, 89.19%, 93.75%, 91.67%, and 93%, respectively.</p><p><strong>Conclusion: </strong>The combination of multimodal ultrasound and BI-RADS provides a significant improvement in the diagnostic accuracy and sensitivity for NMLs, offering a more comprehensive and reliable diagnostic tool for evaluating NMLs.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value of Contrast-Enhanced Ultrasound in Detecting Abdominal Metastases From Gastrointestinal Stromal Tumors.","authors":"Hong Yue, Xuemei He, Jing Sun, Jiangyan Yin, Chongqing Cheng, Tiantian Wang","doi":"10.1002/jcu.70114","DOIUrl":"https://doi.org/10.1002/jcu.70114","url":null,"abstract":"<p><strong>Objective: </strong>To assess the diagnostic performance of contrast-enhanced ultrasound (CEUS) for detecting abdominal metastases in patients with gastrointestinal stromal tumors (GISTs), with a comparison to conventional ultrasonography (US) and contrast-enhanced computed tomography (CE-CT).</p><p><strong>Methods: </strong>This retrospective study enrolled 53 patients with pathologically confirmed abdominal metastases from gastrointestinal stromal tumors (GISTs), who underwent US, CEUS, and CE-CT examinations at our institution between January 2022 and January 2025. The diagnostic performance of CEUS was systematically evaluated and compared with US and CE-CT according to pathological diagnostic criteria.</p><p><strong>Results: </strong>CEUS showed significantly higher sensitivity than US (88.68% vs. 45.28%; p < 0.05). Notably, CEUS achieved comparable performance to CE-CT (sensitivity: 88.68% vs. 94.34%; p > 0.05). No statistically significant differences were observed between CEUS and CE-CT in lesion perfusion characteristics, including enhancement pattern (p > 0.05), intensity (p > 0.05), and homogeneity (p > 0.05).</p><p><strong>Conclusions: </strong>CEUS demonstrates superior diagnostic performance to US in detecting abdominal metastases from GISTs, with efficacy comparable to CE-CT. Given its radiation-free nature and procedural simplicity, CEUS represents a valuable imaging modality for the clinical assessment of GIST metastases.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normal Thyroid Volume and Shear Wave Elastography Values in Asymptomatic Infants.","authors":"Merve Yazol, Tunjay Mammadov, Asude Badem, Öznur Leman Boyunağa","doi":"10.1002/jcu.70109","DOIUrl":"https://doi.org/10.1002/jcu.70109","url":null,"abstract":"<p><p>This study provides preliminary reference values for thyroid volume and stiffness in asymptomatic infants. Thyroid volume increased with age, while stiffness remained stable until 180 days and increased thereafter. Shear wave elastography may serve as a valuable, non-invasive tool for early thyroid assessment and monitoring in infancy.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145280182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}