Assessment of Left Ventricular Function by Echocardiographic Imaging in Patients Non-ST Segment Elevation ACS Undergoing Successful Percutaneous Revascularization Therapy.
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引用次数: 0
Abstract
Background: There are insufficient studies on beneficial outcomes of successful percutaneous coronary intervention (PCI) in the evaluation of contractile left ventricular (LV) function for acute coronary syndrome (ACS) patients without ST elevation. The study aimed to detect the effect of revascularization on LV recovery using non-invasive biomechanical markers.
Methods: A total of 30 successful PCI patients (mean age 56 ± 9 years) with preserved ejection fraction (EF) underwent two-dimensional (2D)-echocardiography before PCI, as early as 1 day after PCI, and 3 months follow-up. LV function assessment was carried out using conventional echocardiographic parameters. Global longitudinal and circumferential strain with 2D speckle tracking echocardiography (2D-STE) and elastic modulus (E) parameters were calculated to evaluate myocardial function.
Results: There were significant improvements in the value of global strain and E parameters, 1 day after PCI (p < 0.05) and also 3 months after PCI (p < 0.05) as compared to values before PCI (p < 0.05). Strain changes 1 day after PCI and also 3 months after PCI as compared to values before PCI (p < 0.05) with changes in EF, demonstrated moderate correlation with a significant statistical difference (r = 0.6, p < 0.05). GLS and GCS parameters significantly improved LV recovery from before PCI to follow-up (AUC 0.86 and 0.91 with 87% sensitivity, respectively, and p < 0.001).
Conclusions: Calculated global strain and elastic modulus parameters were more sensitive and superior non-invasive markers to evaluate early LV improvement after coronary revascularization and helpful to differentiate the pre-PCI from the post-PCI group.
期刊介绍：
The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography.
The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents.
JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.
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