Dan Ma, Tao Yuan, Zhihui Zhao, Lan Zeng, Jin Wang, Xiaocheng Nie, Huping Liang, Guanghuan Pi, Ai Chen, Gen Li, Biao Tang, Shuyao Zhu
{"title":"Prenatal diagnosis of monozygotic twins with phenotypic differences in chromosome 17q12 deletion syndrome.","authors":"Dan Ma, Tao Yuan, Zhihui Zhao, Lan Zeng, Jin Wang, Xiaocheng Nie, Huping Liang, Guanghuan Pi, Ai Chen, Gen Li, Biao Tang, Shuyao Zhu","doi":"10.1002/jcu.23814","DOIUrl":"10.1002/jcu.23814","url":null,"abstract":"<p><p>We present a case study highlighting prenatal ultrasound findings in monozygotic twins with chromosome 17q12 deletion syndrome. Fetus A exhibited bilateral fetal pyelectasis and talipes equinovarus, while fetus B showed hyperechogenic kidneys. Despite sharing the same de novo variant, the twins displayed distinct clinical phenotypes, suggesting the presence of non-genetic factors influencing the phenotypic variability of this syndrome. This case represents the first documented instance of prenatally identified identical twins affected by 17q12 deletion syndrome.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The added value of superb microvascular imaging for renal cortical thickness measurement in chronic kidney disease.","authors":"Poemporn Limpisook, Pooriput Waongenngarm, Surachate Siripongsakun, Nannapat Nuangchamnong, Nutsurang Promrach, Thananya Thabsangthong","doi":"10.1002/jcu.23796","DOIUrl":"10.1002/jcu.23796","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate renal parenchymal thickness and renal cortical thickness measurements on brightness mode ultrasound (B-mode US) and B-mode US + Superb Microvascular Imaging (SMI) technique, comparing with computed tomography (CT) or magnetic resonance imaging (MRI) serving as a reference standard.</p><p><strong>Methods: </strong>Renal parenchymal thickness and renal cortical thickness measurements were obtained from B-mode US, B-mode US + SMI, and CT/MRI in a group of healthy subjects and a group of patients with chronic kidney disease (CKD). The mean differences and correlations of renal parenchymal thickness and renal cortical thickness were analyzed using dependent pair t-test and Pearson's correlation, respectively.</p><p><strong>Results: </strong>The mean difference in renal cortical thickness measurements between B-mode US + SMI and CT/MRI was lower than the mean difference between B-mode US alone and CT/MRI. Additionally, renal cortical thickness measured using B-mode US + SMI showed a stronger correlation with values obtained from CT/MRI than values measured using standard B-mode US alone.</p><p><strong>Conclusion: </strong>The measurement of renal cortical thickness by B-mode US + SMI is more accurate than that by B-mode US alone.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fetal echogenic bowel may be related to intestinal microbiota: A prospective cohort study.","authors":"Yanping Zhao, Guorong Lyu","doi":"10.1002/jcu.23794","DOIUrl":"10.1002/jcu.23794","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of the current study was to determine the difference in intestinal microbiota after delivery between healthy fetuses and fetuses with hyperechogenic bowel during the second trimester and the relationship between fetal echogenic bowel and microbiota.</p><p><strong>Methods: </strong>Fourteen healthy fetuses (control group), 13 fetuses with echogenic bowel (EB group), and seven fetuses with echogenic bowel and other abnormalities (C-EB group) were selected. The first meconium after delivery was collected for 16S rRNA sequencing.</p><p><strong>Results: </strong>A total of 1 222 131 high-quality sequences were generated after sequencing optimization of all samples. Each sample contained an average of 35 945 high-quality sequences and 2036 operational taxonomic units (OTUs). There was no significant difference in the Shannon, Simpson index among the three groups. At the genus level, the abundance of Escherichia coli/Shigella in the EB and C-EB groups was significantly lower than the control group, while the abundance of Staphylococcus, Methylobactrium, and Curvibacter in the EB group was significantly higher than the other groups. There was a difference in abundance of Gammaproteobacteria, Fusobacteria, Enterobacteriaceae, and E. coli in the EB and C-EB groups.</p><p><strong>Conclusions: </strong>The formation of echogenic bowel may be related to the microbiota.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myocardial work in idiopathic premature ventricular contractions: Assessing left ventricular function and prognosis.","authors":"Chunrui Zhou, Qian He, Yunchuan Ding, Qinghui Wang, Lini Xian, Xin Peng, Fuyong Mao, Qingqing Luo, Zefan Yang, Ping Yang, Jian Chen","doi":"10.1002/jcu.23798","DOIUrl":"10.1002/jcu.23798","url":null,"abstract":"<p><strong>Background: </strong>Premature ventricular contractions (PVCs) can lead to impairment of left ventricular function. The noninvasive myocardial work technique, which incorporates left ventricular afterload, represents a new method for assessing left ventricular functional.</p><p><strong>Aim: </strong>The aim of this study is to explore the value of noninvasive myocardial work technique in assessing left ventricular systolic function in patients with PVCs.</p><p><strong>Methods: </strong>Compare the clinical data, two-dimensional echocardiography parameters, and myocardial work parameters of 66 patients with PVCs and 35 healthy volunteers and explore the relevant risk factors for postoperative recurrence in patients with PVCs.</p><p><strong>Results: </strong>In patients with PVCs compared to the control group, they exhibit enlargement of left atrial diameter (LAD) and left ventricular internal dimension in diastole (LVIDd), as well as thickening of the left ventricular wall. The global work waste (GWW) increases, while the global work efficiency (GWE) decreases. There is a significant negative correlation between the PVC burden and GWE (r = -0.70, p <0.01), and a significant positive correlation between the PVC burden and GWW (r = 0.58, p <0.01). GWE is a sensitive indicator for predicting the recurrence of PVCs after radiofrequency ablation. Patients with GWE <91.5%, global longitudinal strain (GLS) <15.5%, and ejection fraction (EF) <62.5% have a higher postoperative recurrence rate.</p><p><strong>Conclusion: </strong>PVCs can cause impairment of left ventricular systolic function. GWE is the most sensitive indicator for predicting postoperative recurrence in patients with PVCs. Patients with GWE <91.5%, GLS <15.5%, and EF <62.5% have a higher postoperative recurrence rate.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristiana do Amaral Coutinho, Pedro Teixeira Castro, Flávia Paiva Lopes, Luiz Alberto Coutinho de Freitas Lima, Edward Araujo Júnior, Osvaldo Luis Aranda, Luiz Felipe Bittencout de Araújo, Edson Marchiori, Heron Werner
{"title":"Elastographic and vascular findings of uterine myomas assessed by ultrasound.","authors":"Cristiana do Amaral Coutinho, Pedro Teixeira Castro, Flávia Paiva Lopes, Luiz Alberto Coutinho de Freitas Lima, Edward Araujo Júnior, Osvaldo Luis Aranda, Luiz Felipe Bittencout de Araújo, Edson Marchiori, Heron Werner","doi":"10.1002/jcu.23784","DOIUrl":"10.1002/jcu.23784","url":null,"abstract":"<p><strong>Objective: </strong>The objectives of this study were to evaluate the vascularization pattern of uterine myoma (UM) by ultrasonography using Superb Microvascular Imaging (SMI) and tissue stiffness elastography.</p><p><strong>Method: </strong>A prospective and cross-sectional study was carried out between March 2020 and December 2022 among women with clinical and ultrasound diagnosis of UM who would subsequently undergo radiofrequency ablation. Ultrasound examination was performed using both transvaginal and transabdominal routes. UM vascularization pattern was assessed by power Doppler (PD) and SMI, while elastographic pattern was assessed by shear wave (SWE) and strain (STE). FIGO classification, location, and measurement of the largest UM were also described.</p><p><strong>Results: </strong>A total of 21 women diagnosed with UM were evaluated. There was a predominance of nulliparous women and 20 women (95.2%) reported desire for pregnancy. Of the 18 women with abnormal uterine bleeding, 15 (83.3%) had abdominal cramping. As far as previous treatment, 7 (33.3%) had undergone myomectomy for other UM. The mean uterine and UM volumes were 341.9 cm<sup>3</sup> (90-730) and 126.52 cm<sup>3</sup> (6.0-430), respectively. There was a predominance of hypoechogenic lesions (90.5%). There was also preponderance of UM in the FIGO 2-5 classification (n = 9; 42.9%). Vascularization patter was mostly moderate (score 2) in 9 cases (42.9%). The majority of UM were considered to have intermediate stiffness (n = 10; 47.6%).</p><p><strong>Conclusion: </strong>The majority of UM showed vascularization and moderate stiffness. A relationship was observed between the stiffness of the UM assessed by elastography and its FIGO classification.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141988085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The significance of assessing the umbilical cord on the placental side: A case report on fused umbilical arteries.","authors":"Didem Kaymak, Arzu Dobral, Simge Berrak Beyoglu Oruc, Halil Korkut Daglar","doi":"10.1002/jcu.23805","DOIUrl":"10.1002/jcu.23805","url":null,"abstract":"<p><p>This report details the case of a fetus with fused umbilical arteries (FUAs), which exhibited the presence of a single umbilical artery near the site of placental insertion, as well as normal two umbilical arteries at the fetal end of the umbilical cord. In our case, as the pregnancy progressed, there was an occurrence of late-onset fetal growth restriction and oligohydramnios. This is a possibility that FUAs might impact the development of the fetus.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the ability of laboratory, ultrasonography, and Doppler ultrasonography findings to distinguish between simple and complicated appendicitis.","authors":"Sabriye Gulcin Bozbeyoglu, Neslihan Gulcin","doi":"10.1002/jcu.23811","DOIUrl":"10.1002/jcu.23811","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the utility of laboratory ultrasonographic and Doppler ultrasonographic findings in the differentiation of simple and complicated appendicitis.</p><p><strong>Methods: </strong>A prospective study was conducted, including pediatric patients who underwent surgery with the diagnosis of appendicitis.</p><p><strong>Results: </strong>Fifty patients, who were found to have appendicitis on ultrasonographic examination, were included. The mean age was found to be 12.80 ± 3.67 years, with 30% female and 70% male. The patients were histopathologically divided into two groups: simple appendicitis (Group 1, 41 patients, 82%) and complicated appendicitis (Group 2, 9 patients, 18%). CRP (C-reactive protein) levels (p = 0.004) and periappendiceal fatty tissue thickness (PFI) (p < 0.005) were found to be statistically significantly higher in Group 2 compared to Group 1. The portal vein (PV) diameter and peak systolic velocity (PSV) values were significantly higher in the study group compared to the control group (p = 0.033, p = 0.001).</p><p><strong>Conclusion: </strong>Doppler ultrasonographic examination did not significantly differentiate complicated from simple appendicitis. The CRP value is an independent risk factor in the diagnosis of complicated appendicitis, and the presence of a significant increase in mesenteric tissue thickness is one of the important criteria for differentiating complicated appendicitis from simple appendicitis.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence applications spreading into editorship: A critical conundrum for editors and publishers.","authors":"Gabriele Tonni, Valter Andrade","doi":"10.1002/jcu.23816","DOIUrl":"10.1002/jcu.23816","url":null,"abstract":"","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prospective evaluation of ultrasonographic fetal cardiac morphometry and functions in the third trimester of pregnancies with gestational diabetes mellitus.","authors":"Dilara Duygulu, Bengü Mutlu Sütcüoğlu, Ezgi Turgut, Halis Özdemir, Deniz Karçaaltıncaba","doi":"10.1002/jcu.23776","DOIUrl":"10.1002/jcu.23776","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare cardiac morphological and functional changes in fetuses of patients with diet-regulated gestational diabetes mellitus (GDM-A1), insulin-regulated GDM (GDM-A2), and a control group.</p><p><strong>Method: </strong>A prospective cohort study included pregnant women aged 18-40 years with singleton pregnancies. Fetal biometric, cardiac morphological, and functional measurements were recorded using Z-scores at 34-37 weeks of gestation.</p><p><strong>Results: </strong>The study included 87 patients. Both right and left ventricular wall thicknesses were significantly different between the three groups (p < 0.001 and p < 0.001, respectively). Z-scores of the mitral valve, left and right EDD were significantly lower in GDM-A1 and GDM-A2 groups compared to the control group (p < 0.001, p < 0.001, p = 0.002, respectively). Right and left ventricular areas were decreased only in GDM-A2 group compared to the control group (p = 0.003 and p = 0.001, respectively). MPI and IVRT values were also significantly higher in the same groups (p = 0.016, p < 0.001, respectively).</p><p><strong>Conclusion: </strong>Gestational diabetes increased IVS and ventricular wall thicknesses in both right and left ventricles, irrespective of whether it was controlled by diet or insulin. Cardiac functional changes were observed in the GDM-A2 group.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial neural network prediction of postoperative complications in papillary thyroid microcarcinoma based on preoperative ultrasonographic features.","authors":"Zhanxiong Yi, Enhui He, Peipei Yang, Zhixiang Wang, Xiangdong Hu, Ying Feng","doi":"10.1002/jcu.23800","DOIUrl":"10.1002/jcu.23800","url":null,"abstract":"<p><strong>Objective: </strong>To predict post-thyroidectomy complications in papillary thyroid microcarcinoma (PTMC) patients using a deep learning model based on preoperative ultrasonographic features. This study addresses the global rise in PTMC incidence and the challenges in treatment decision-making with high-resolution ultrasonography.</p><p><strong>Method: </strong>This study enrolled 1638 patients with clinically staged cN0 PTMC who received surgical treatment from 1997 to 2019 at Beijing Friendship Hospital. Deep learning model was developed using fully connected neural network. Feature selection included 1000 iterations of Bootstrap sampling and Recursive Feature Elimination (RFE) to identify the top 10 features. Data preprocessing involved normalization and imputation for missing values. SMOTE addressed class imbalance. The model was trained and tested on random data split, with performance metrics including Accuracy (ACC), Area Under the Curve (AUC), Sensitivity (SEN), and Specificity (SPE), visualized through a ROC curve and confusion matrix.</p><p><strong>Results: </strong>The fully connected deep neural network model demonstrated high accuracy (ACC 0.81), Area Under the Curve (AUC 0.74), sensitivity (SEN 0.65), and specificity (SPE 0.83) and visualized by ROC curve and confusion matrix. These results highlight the model's reliability and potential as an effective tool in predicting postoperative complications and assisting in clinical decision-making for PTMC patients.</p><p><strong>Conclusion: </strong>This study highlights the potential of deep learning in enhancing medical predictions and personalized healthcare. Despite promising results, limitations include a single-center data source and unconsidered factors like lifestyle and genetics. Future research should expand data sources, include more influencing factors, and refine algorithms to improve accuracy and applicability in thyroid cancer treatment.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}