Journal of Clinical Ultrasound最新文献

{"title":"Correlation Between Computer-Assisted Ultrasonographic Parameters and Histological Findings in Glomerular Diseases: A Multivariate Ordinal Analysis","authors":"Nordeval Cavalcante Araújo,&nbsp;Lilimar da Silveira Rioja,&nbsp;José Hermógenes Rocco Suassuna","doi":"10.1002/jcu.70297","DOIUrl":"10.1002/jcu.70297","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>This study aimed to correlate renal ultrasonographic and Doppler parameters with histological findings from kidney biopsies using computer-assisted image analysis. Objective measures included the cortical-to-liver (or spleen) echogenicity ratio, corticomedullary ratio (CMR), renal resistivity index (RRI), splenic resistivity index (SRI), and a derived index (DI-RISK).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The patients' age and CKD-EPI–derived estimated glomerular filtration rate (eGFR) were recorded. Histological lesions encompassed all components of the lupus nephritis activity and chronicity indices. Ultrasound images were analyzed to extract grayscale values from manually defined regions of interest. RRI was measured in interlobar arteries, and SRI at the intraparenchymal splenic artery. The DI-RISK index expressed the RRI difference from the SRI as a percentage of the RRI. Associations were evaluated using multivariate ordinal logistic regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Increased cortical echogenicity was independently correlated with severe interstitial fibrosis/tubular atrophy (IF/TA) and lower eGFR. CMR was reduced in the presence of interstitial infiltrates. IF/TA was also associated with reduced kidney size. While resistivity indices correlated with vascular lesions, age, and eGFR in the univariate analysis, only age and eGFR remained significant in the multivariate models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Computer-assisted ultrasonography correlates with key histological changes. Cortical echogenicity and kidney size may help identify advanced chronic damage noninvasively.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1885-1893"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148211455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Performance of Diffusion-Weighted Imaging for Evaluation of Breast Lesions: Correlation With Prognostic Factors and Histological Phenotypes","authors":"Osman Konukoglu,&nbsp;Murat Kaya,&nbsp;Baris Can Arslan","doi":"10.1002/jcu.70303","DOIUrl":"10.1002/jcu.70303","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To investigate the role of diffusion-weighted imaging (DWI) in the differential diagnosis of breast lesions and to determine whether there is an association with histological subtypes and prognostic factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials &amp; Methods</h3>\u0000 \u0000 <p>This retrospective study was approved by our institution's ethics committee. A total of 456 patients who underwent ultrasound-guided tru-cut biopsy between January 2024 and January 2025 were evaluated. Patients who had pre-biopsy breast MRI examinations with diagnostically adequate DWI sequences were included. Apparent diffusion coefficient values (ADC_mean and ADC_ratio) were measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age of the patients was 46.79 ± 12.55 years. A total of 96 breast masses were evaluated in the study, of which 44.79% (<i>n</i> = 43) were benign, and 55.21% (<i>n</i> = 53) were malignant. A statistically significant difference was observed between the benign group (1.22 ± 0.24 × 10⁻³ mm²/s) and the malignant group (0.76 ± 0.18 × 10⁻³ mm²/s) in terms of ADC_mean values (<i>p</i> &lt; 0.001). The cut-off value for the ADC_mean was determined to be 0.955 × 10⁻³ mm²/s (<i>p</i> &lt; 0.001). No statistically significant association was found among histological phenotypes within the malignant group (<i>p</i> &gt; 0.05). A statistically significant difference in ADC_ratio values was observed between HER2-negative cases (0.56 ± 0.12) and HER2-positive cases (0.49 ± 0.14) (<i>p</i> = 0.043).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>DWI and ADC represent reliable methods for distinguishing between benign and malignant breast lesions. The observed association between ADC_ratio values and HER2 expression suggests that this parameter may be useful in identifying breast cancer patients with poor prognostic profiles.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1922-1930"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148251765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Second-Look Ultrasound for MRI-Detected Lesions: MRI Features, Detection Rate, and Sonographic Findings","authors":"Selda Guven,&nbsp;Baki Hekimoglu,&nbsp;Ata T. Arikok,&nbsp;Irmak Durur-Subasi","doi":"10.1002/jcu.70274","DOIUrl":"10.1002/jcu.70274","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Second-look US emerged as a feasible tool to evaluate MRI-detected lesions, although data regarding the accuracy and optimal lesion selection for second-look US is limited. Therefore, we evaluated the second-look US detection rate of breast lesions detected initially on MRI by using MRI features and compared second-look US findings across benign and malignant lesions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A total of 110 MRI-detected lesions subsequently evaluated with the second-look US were retrospectively reviewed. The performance of MRI features in the prediction of second-look US detection was evaluated with ROC analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The positive and negative predictive values of second-look US for malignancy detection were 28.8% and 96.1%, respectively. In multivariate analyses, the MRI BI-RADS category (OR: 11.896, <i>p</i> &lt; 0.001) and lesion type (OR: 9.470, <i>p</i> = 0.001) were significantly associated with second-look US detection. Combined scoring with these factors could predict second-look US detection [AUC: 0.712, 95% CI: 0.617–0.807 <i>p</i> &lt; 0.001]. Furthermore, lesions with irregular shapes and margins were more often malignant in the analysis of US findings (<i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The MRI BI-RADS category and lesion type could predict detection in the second-look US for MRI-detected lesions. Besides, second-look US could give additional information to distinguish between benign and malignant masses.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1829-1835"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Lung Ultrasound in Diagnosing Pediatric Pneumonia and Outcomes in Implementation of Its Quality Control System","authors":"Linlin Zhang,&nbsp;Xinhua Sun,&nbsp;Chengbo Jin,&nbsp;Haiyuan Wu","doi":"10.1002/jcu.70309","DOIUrl":"10.1002/jcu.70309","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This study aims to investigate the effectiveness of lung ultrasound (LUS) in diagnosing pediatric pneumonia and the outcomes of implementing a “personnel-equipment-operation-interpretation-feedback” quality control system.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective study was made on 479 pediatric patients with suspected pneumonia. The LUS, chest digital radiography (DR), and chest computed tomography (CT) were performed on the patients, and the sensitivity, specificity, positive predictive value, and negative predictive value (NPV) of the three inspection methods were compared using comprehensive clinical diagnosis as the reference standard. In addition, a “personnel-equipment-operation-interpretation-feedback” quality control system of LUS was constructed and implemented in 412 cases, and the diagnosis accordance rate, image qualification rate, and operation standardization rate of LUS before and after implementation of the quality control system were compared.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The sensitivity, specificity, and NPV of LUS for pediatric pneumonia were significantly higher than those of CT and DR, respectively (<i>p</i> &lt; 0.05). After implementation of the quality control system, the diagnosis accordance rate, image qualification rate, and operation standardization rate of LUS significantly increased compared with before implementation of the quality control system (<i>p</i> &lt; 0.05). In addition, after implementation of the quality control system, its main items were significantly improved compared with before.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>LUS has good diagnostic effectiveness for pediatric pneumonia. The construction and implementation of this multidimensional LUS quality control system can effectively improve the accuracy and reliability of diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1967-1972"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of Patent Foramen Ovale: Transcranial Doppler and Echocardiography Are Not Equivalent to Define a Large Shunt","authors":"Thomas Codant,&nbsp;Pauline Renou,&nbsp;Georgios Papaioannou,&nbsp;Jean-Benoît Thambo,&nbsp;Carine Boulon,&nbsp;Damien Barcat,&nbsp;Joël Constans,&nbsp;Loubna Dari","doi":"10.1002/jcu.70278","DOIUrl":"10.1002/jcu.70278","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The decision to close patent foramen ovale (PFO) depends on the size of PFO, the coexistence of interatrial septum aneurysm, and the importance of right-to-left shunt assessed by the number of bubbles on transcranial Doppler (TCD) and echocardiography after saline or glucose injection. The interventional threshold for the number of bubbles is considered to be the same for trans-thoracic and trans-esophageal echocardiography (TTE and TEE) and TCD. Our objective was to study whether the same thresholds can be used for TCD and echocardiography.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and Methods</h3>\u0000 \u0000 <p>In this comparative, observational study, we modeled a linear relationship between the number of bubbles on TCD and echocardiography, which suggests a different threshold between TCD and TTE/TEE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We found a systematic difference between TTE/TEE and TCD for the number of bubbles in the same patient. From linear regression, we found the following equation: TCD_Estimate = (7.2 (95% CI: −2.36–16.8) + (2.67 (95% CI: 1.85–3.49, <i>p</i> &lt; 0.001)) × <i>TTE/TEE</i>).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Different thresholds for the decision to close a PFO should be used for both techniques: 20 bubbles for echocardiography and 60 bubbles for TCD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1836-1841"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148042402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal Outcomes of Placental Chorangioma: A Single Center Study","authors":"Tseten Zangmu Bhutia,&nbsp;Saritha Redishetty,&nbsp;Smita Pawar,&nbsp;Arati Singh,&nbsp;Geeta Kolar,&nbsp;Suseela Vavilala","doi":"10.1002/jcu.70301","DOIUrl":"10.1002/jcu.70301","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To determine the incidence of placental chorangioma and evaluate its associated perinatal complications and mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methodology</h3>\u0000 \u0000 <p>A retrospective observational study was conducted at Fernandez Hospitals, Hyderabad, India, from March 2011 to March 2025. All singleton pregnancies with structurally normal fetuses diagnosed antenatally with placental chorangioma and delivered at our center, with postnatal confirmation by histopathological examination (HPE), were included in the study. The diagnosis was made using B-mode ultrasound examination and color Doppler flow imaging, demonstrating a well-circumscribed hypo or hyperechoic placental mass with a clearly identifiable vascular supply. Demographic details, prenatal sonographic findings, perinatal and neonatal outcomes were collected from electronic medical records.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 20 cases were included, with an incidence of 9.8 per 100 000 pregnancies. Large chorangiomas (≥ 4 cm) accounted for 90% of cases, while small chorangiomas (&lt; 4 cm) accounted for 10%. The mean gestational age at diagnosis was 27.65 ± 5.27 weeks. Sixteen cases (80%) were managed conservatively, while four cases (20%) required prenatal intervention. Polyhydramnios was observed in 12 (60%) fetuses and cardiomegaly in 5 (25%). Fifteen fetuses (75%) were appropriate for gestational age, four (20%) had fetal growth restriction, and one (5%) was large for gestational age secondary to hydrops. Eleven pregnancies (55%) resulted in preterm birth. Nine neonates (45%) required admission to the neonatal intensive care unit (NICU), and eight (40%) experienced adverse neonatal outcomes. No neonatal deaths occurred despite the predominance of large chorangiomas in the study population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Serial ultrasound surveillance with meticulous fetal assessment enabled early identification of asymptomatic chorangiomas and timely intervention when required, resulting in favorable perinatal outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1904-1911"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148239212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application Value of Lung Ultrasound in Children With Macrolide-Unresponsive Mycoplasma pneumoniae Pneumonia","authors":"Jie Zhou,&nbsp;Xinxin Guo,&nbsp;Rong Wu","doi":"10.1002/jcu.70293","DOIUrl":"10.1002/jcu.70293","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The incidence of macrolide-unresponsive <i>Mycoplasma pneumoniae</i> pneumonia (MUMPP) has markedly increased, primarily owing to resistance mediated by mutations in the pathogen's 23S rRNA gene. Because macrolide susceptibility testing is impractical at admission, this study aimed to delineate the clinical characteristics of MUMPP in children and to evaluate the predictive utility of laboratory parameters and lung ultrasound features for identifying MUMPP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis was performed on 163 children hospitalized with <i>Mycoplasma pneumoniae</i> pneumonia (MPP) at the Department of Pediatrics, Ordos Central Hospital, from January 1, 2023, to December 31, 2024. Patients were stratified into the MUMPP group (<i>n</i> = 49) and the macrolide-sensitive <i>Mycoplasma pneumoniae</i> pneumonia (MSMP) group (<i>n</i> = 114) according to their response to macrolide antibiotics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared with the MSMP group, patients in the MUMPP group were older, had longer hospital stays, and had higher body temperatures. <span>d</span>-dimer levels and neutrophil-to-lymphocyte ratios (NLRs) were elevated in the MUMPP group. On lung ultrasound, the MUMPP group exhibited larger areas of lung consolidation at admission and after treatment, higher rates of pleural effusion, greater bilateral pulmonary involvement, and a higher proportion of consolidations without air bronchograms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Children with MUMPP present with more severe clinical features and lung ultrasound manifestations than those with MSMP. Early initiation of non-macrolide alternative therapies is therefore critical for effective management of MUMPP.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1876-1884"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148205253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Accuracy of Shear Wave Elastography for the Assessment of Congestive Liver Disease in Patients With Structural Heart Disease","authors":"Edinéia Camargo Dziadzio,&nbsp;Maria Angelica Jungles Malikoski,&nbsp;Eduardo Henrique Bonotto,&nbsp;Sandra Monica Tochetto,&nbsp;Marco Stephan Lofrano-Alves","doi":"10.1002/jcu.70283","DOIUrl":"10.1002/jcu.70283","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Shear wave elastography (SWE) is widely used to assess liver stiffness in chronic liver disease. Increased stiffness may also occur in congestive liver disease (CLD) due to hepatic venous congestion in patients with cardiovascular disease, but data on its diagnostic performance remain limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the diagnostic performance of SWE for detecting CLD in outpatients with structural heart disease undergoing investigation for liver disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Consecutive patients referred for SWE between 2018 and 2023 were retrospectively reviewed. CLD was defined by compatible liver imaging findings and structural heart disease on transthoracic echocardiography. Diagnostic performance was assessed using ROC analysis. Associations between liver stiffness and echocardiographic parameters were evaluated using correlation and partial correlation analyses, and determinants of liver stiffness were assessed using multiple linear regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>About 88 patients were included (17 with CLD). Liver stiffness was higher in CLD compared with non-CLD patients (8.4 [7.5–9.6] vs. 7.2 [6.5–8.2] kPa, <i>p</i> &lt; 0.001). A cutoff &gt; 7.54 kPa yielded an AUC of 0.757, with 81.2% sensitivity and 63.4% specificity. CLD was associated with right ventricular dilation and greater tricuspid regurgitation severity. Significant correlations were observed with right ventricular diameter, pulmonary artery systolic pressure, right atrial volume, and left atrial volume index. In multiple linear regression, CLD remained the only independent determinant of liver stiffness.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>SWE shows moderate diagnostic accuracy for detecting congestive hepatopathy in patients with structural heart disease. Liver stiffness appears to reflect systemic venous congestion rather than isolated hepatic structural disease.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1867-1875"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jcu.70283","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Ultrasonographic Transcerebellar Diameter for Gestational Age Estimation: A Systematic Review and Meta-Analysis","authors":"Ammar Elgadi,&nbsp;Mohammed Wagealla,&nbsp;Elwalid Idris,&nbsp;Abdullatif Yasir H. Eissa,&nbsp;Sara Altraifi,&nbsp;Hajir Altraifi,&nbsp;Eman Abdallah,&nbsp;Tibyan Noorallah,&nbsp;Eltayeb AbdAlla","doi":"10.1002/jcu.70300","DOIUrl":"10.1002/jcu.70300","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Accurate estimation of gestational age (GA) is essential in prenatal care and assessment of perinatal outcomes. Standard dating methods such as last menstrual period (LMP) or conventional ultrasound biometry may be limited by fetal position, late antenatal booking, or intrauterine growth restriction (IUGR). The transcerebellar diameter (TCD) has been proposed as a robust alternative for GA estimation, particularly in late gestation or when other methods are unreliable. This study systematically evaluates the accuracy of TCD-based GA estimation in the second and third trimesters in both normal and IUGR pregnancies.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methodology&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;We conducted a systematic review and meta-analysis in accordance with the PRISMA guidelines. Databases including PubMed, Scopus, and ScienceDirect were searched from inception through July 2025 for studies assessing the correlation between TCD and GA. Google Scholar was also searched for relevant articles. Inclusion criteria were original studies reporting correlation coefficients between TCD and GA determined by LMP or first-trimester ultrasound. Data extraction and risk of bias assessments were performed independently by two reviewers. Meta-analyses were conducted using random-effects models in R.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In this meta-analysis of 47 studies comprising 24 825 participants, the pooled correlation between TCD and GA was consistently strong. In the third trimester, &lt;i&gt;r&lt;/i&gt; = 0.94 (95% CI: 0.89–0.97); in the second trimester, &lt;i&gt;r&lt;/i&gt; = 0.93 (95% CI: 0.87–0.96); and across the combined second or third trimester, &lt;i&gt;r&lt;/i&gt; = 0.98 (95% CI: 0.97–0.98). This was comparable to other fetal biometric parameters: BPD (&lt;i&gt;r&lt;/i&gt; = 0.97), HC (&lt;i&gt;r&lt;/i&gt; = 0.97), FL (&lt;i&gt;r&lt;/i&gt; = 0.98), and AC (&lt;i&gt;r&lt;/i&gt; = 0.97), with no statistically significant differences in pairwise comparisons (&lt;i&gt;p&lt;/i&gt; &gt; 0.05). In pregnancies affected by IUGR, TCD correlation with GA (&lt;i&gt;r&lt;/i&gt; = 0.94, 95% CI: 0.89–0.97) was significantly higher than that of other biometric measures: BPD (&lt;i&gt;r&lt;/i&gt; = 0.69), HC (&lt;i&gt;r&lt;/i&gt; = 0.72), FL (&lt;i&gt;r&lt;/i&gt; = 0.80), and AC (&lt;i&gt;r&lt;/i&gt; = 0.78) (&lt;i&gt;p&lt;/i&gt; &lt; 0.001).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;TCD is a reliable and highly reproducible parameter for gestational age estimation, with strong correlations in late pregnancy. In pregnancies affected by IUGR, TCD was superior to other parameters. Its short learning curve and standardized methodology support its clinical utility as a complementary or primary tool for GA assessment, particularly in late pregnancy or when standard methods are limited","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1942-1956"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-Based Evaluation and Diagnostic Discordance in Pediatric Thyroglossal Duct Cysts","authors":"Neslihan Gulcin,&nbsp;Cengiz Gul,&nbsp;Mehmet Arpacik,&nbsp;Semih L. Mirapoglu,&nbsp;H. Banu Zoroglu,&nbsp;Aytekin Kaymakci,&nbsp;Ceyhan Sahin","doi":"10.1002/jcu.70282","DOIUrl":"10.1002/jcu.70282","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Ultrasonography is the first-line imaging modality for evaluating thyroglossal duct cysts (TGDCs); however, its diagnostic accuracy in differentiating TGDCs from other congenital midline cystic neck lesions remains limited. This study aimed to evaluate the concordance between preoperative clinical and ultrasonographic diagnoses and final pathological findings in pediatric patients with presumed TGDC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective single-center study included pediatric patients who underwent surgery for a presumed TGDC between January 2015 and December 2025. Preoperative diagnosis was based on combined clinical examination and ultrasonographic findings. Demographic characteristics, presenting symptoms, imaging findings, pathological diagnoses, and postoperative outcomes were analyzed. Ultrasound findings were retrospectively assessed using the SIST scoring system. Comparisons were performed between patients with pathologically confirmed TGDC and those with non-TGDC pathology.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 42 pediatric patients were included; 78.6% were male, and the mean age was 5.97 ± 3.79 years. Final pathological examination confirmed TGDC in 32 patients (76.2%), whereas 10 patients (23.8%) had alternative diagnoses. Preoperative SIST scores were significantly higher in patients with TGDC than in those with non-TGDC pathology (<i>p</i> = 0.028). Despite preoperative findings suggestive of TGDC in all patients, a substantial rate of diagnostic discordance was observed. Postoperative outcomes were favorable, with low complication and recurrence rates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Ultrasonography plays a central role in the evaluation of pediatric TGDC; however, it has limitations in accurately distinguishing TGDCs from other midline cystic lesions. Structured ultrasound-based scoring systems such as SIST may improve diagnostic confidence but cannot fully predict final pathology. Clinical and intraoperative findings should therefore be considered alongside imaging in surgical decision-making.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":"54 8","pages":"1860-1866"},"PeriodicalIF":1.3,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148054762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}