{"title":"肝病学中的先进超声定量分析:局灶性肝脏病变表征方法的系统综述。","authors":"Sinan Li, Huiling Liu, Weihong Li, Xiaotao Gao","doi":"10.1002/jcu.70084","DOIUrl":null,"url":null,"abstract":"<p><p>This systematic review evaluates advanced ultrasound quantitative techniques including contrast-enhanced ultrasound, elastography, quantitative ultrasound (QUS), multiparametric ultrasound, and artificial intelligence for characterizing focal liver lesions (FLLs). It critically appraises their technical principles, parameter extraction methodologies, and clinical validation frameworks. It further integrates and comparatively analyzes their diagnostic performance across major FLL subtypes, including hepatocellular carcinoma, metastases, hemangioma, and focal nodular hyperplasia. This work provides a foundation for improving noninvasive FLL diagnosis and highlights the imperative for standardization and clinical translation of advanced QUS in hepatology.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Advanced Ultrasound Quantitative Analysis in Hepatology: A Systematic Review of Methodologies for Characterizing Focal Liver Lesions.\",\"authors\":\"Sinan Li, Huiling Liu, Weihong Li, Xiaotao Gao\",\"doi\":\"10.1002/jcu.70084\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This systematic review evaluates advanced ultrasound quantitative techniques including contrast-enhanced ultrasound, elastography, quantitative ultrasound (QUS), multiparametric ultrasound, and artificial intelligence for characterizing focal liver lesions (FLLs). It critically appraises their technical principles, parameter extraction methodologies, and clinical validation frameworks. It further integrates and comparatively analyzes their diagnostic performance across major FLL subtypes, including hepatocellular carcinoma, metastases, hemangioma, and focal nodular hyperplasia. This work provides a foundation for improving noninvasive FLL diagnosis and highlights the imperative for standardization and clinical translation of advanced QUS in hepatology.</p>\",\"PeriodicalId\":15386,\"journal\":{\"name\":\"Journal of Clinical Ultrasound\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-09-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Ultrasound\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/jcu.70084\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ACOUSTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Ultrasound","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jcu.70084","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ACOUSTICS","Score":null,"Total":0}
Advanced Ultrasound Quantitative Analysis in Hepatology: A Systematic Review of Methodologies for Characterizing Focal Liver Lesions.
This systematic review evaluates advanced ultrasound quantitative techniques including contrast-enhanced ultrasound, elastography, quantitative ultrasound (QUS), multiparametric ultrasound, and artificial intelligence for characterizing focal liver lesions (FLLs). It critically appraises their technical principles, parameter extraction methodologies, and clinical validation frameworks. It further integrates and comparatively analyzes their diagnostic performance across major FLL subtypes, including hepatocellular carcinoma, metastases, hemangioma, and focal nodular hyperplasia. This work provides a foundation for improving noninvasive FLL diagnosis and highlights the imperative for standardization and clinical translation of advanced QUS in hepatology.
期刊介绍:
The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography.
The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents.
JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.