Journal of Clinical Ultrasound最新文献

{"title":"Combination of Doppler US and US Elastography is Superior to Doppler US or US Elastography Alone in Detecting Delayed Kidney Graft Rejection.","authors":"Masume Charmi, Alisa Mohebbi, Saeed Mohammadzadeh, Ali Abbasian Ardakani, Afshin Mohammadi","doi":"10.1002/jcu.70051","DOIUrl":"https://doi.org/10.1002/jcu.70051","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the performance of Doppler ultrasound (US) and US elastography with their combination in detecting delayed graft rejection.</p><p><strong>Methods: </strong>A prospective cross-sectional study of 60 consecutive adult kidney transplant recipients was done. Patients with creatinine > 1.5 mg/dL and a minimum interval of 3 months from renal transplant surgery were recruited. All patients underwent both Doppler US and US elastography. A direct head-to-head comparison was made. A glomerular filtration rate (eGFR) < 50 was regarded as delayed graft rejection. A resistive index (RI) value ≥ 0.79 was considered abnormal.</p><p><strong>Results: </strong>RI was more strongly correlated to age, diabetes mellitus, and hypertension with Pearson correlation coefficients of 0.414, 0.390, and 0.386, respectively, while stiffness (kPa) exhibited a stronger correlation to the time period since surgery. Using radiological findings to estimate observed eGFR showed an adjusted R² of 0.135. Doppler US alone, US elastography alone, and combined Doppler US + US elastography + clinical data, respectively, showed area under curve (AUC) values of 0.668 (95% CI = 0.535 to 0.735), 0.641 (95% CI = 0.507 to 0.761), and 0.792 (95% CI = 0.667 to 0.886) in detecting delayed graft rejection. Estimating RI using clinical and US elastography findings showed AUC of 0.811 (95% CI = 0.689 to 0.901), with sensitivity of 61.5% (95% CI = 40.6 to 79.8) and specificity of 91% (95% CI = 76.3 to 98.1).</p><p><strong>Conclusion: </strong>Monitoring renal allografts using a combination of Doppler US and US elastography, in conjunction with clinical data, may provide additional early diagnostic and clinical advantages.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145064853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Assessment of Downstream Clinical Tasks in Cardiac Ultrasound Is Crucial for Segmentation Evaluation.","authors":"Shihui Zhang, DongJun Zhao, Yun Li, Jiajie Tang, Ruiyan Ma, Jingjing Xiao, Yi Wu","doi":"10.1002/jcu.70065","DOIUrl":"https://doi.org/10.1002/jcu.70065","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the relationship between echocardiography segmentation accuracy and clinical examination indicators by comparing segmentation evaluation metrics (S-EM) with cardiac clinical examination indicators evaluation metrics (CCEI-EM).</p><p><strong>Methods: </strong>Initially, four UNet-based segmentation models for 2D echocardiography were trained using the CAMUS dataset. Subsequently, 13 clinical examination indicators relevant to cardiac assessment were automatically extracted. Pixel accuracy (PA), dice similarity coefficient (DSC), intersection over union (IOU), and Hausdorff distance (HD) were utilized as S-EM to assess the segmentation outcomes. The deformation ratio between these clinical examination indicators and the ground truth was defined as CCEI-EM. Finally, statistical analyses were conducted to examine the correlations between S-EM and CCEI-EM.</p><p><strong>Results: </strong>Statistically significant differences were detected between S-EM and cardiac structural indicator evaluation metrics (p < 0.05). However, weak correlations were identified for the left ventricular transverse diameter and the left ventricular long diameter with PA, DSC, and IOU (p < 0.05; r < 0.2). No statistically significant differences were found between cardiac functional evaluation metrics with PA, DSC, and IOU (p > 0.05); moreover, end-systolic volume demonstrated weak correlations with PA and DSC (p < 0.05; r < 0.2).</p><p><strong>Conclusion: </strong>S-EM does not directly reflect the quality of cardiac clinical examination indicators derived from segmentation results. It is crucial to evaluate segmentation performance through downstream task-related clinical indicators.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145064859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value of Ultrasound in Primary Cervical Ewing's Sarcoma: Two Case Reports and Literature Review.","authors":"Ziwei Wang, Hong Luo","doi":"10.1002/jcu.70050","DOIUrl":"https://doi.org/10.1002/jcu.70050","url":null,"abstract":"<p><p>Primary cervical Ewing's sarcoma (ES) is a rare malignant small round cell tumor that develops outside the bone, with a generally poor prognosis. Clinical symptoms are nonspecific, posing challenges for early diagnosis. In this report, we present two cases of middle-aged women presenting with abnormal vaginal bleeding. Neither human papillomavirus typing nor blood tests showed specific abnormalities. Ultrasound examination identified uneven hypoechoic lesions with well-defined borders in the cervix, and color Doppler imaging showed punctate linear blood flow signals within the lesions. Histopathological biopsies confirmed the diagnosis of primary ES of the uterine cervix. Both patients achieved favorable prognoses following a combined treatment of surgery and chemotherapy. This study highlights the value of ultrasound imaging in aiding the timely diagnosis of this rare malignancy.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145053739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Thyroid Elastography Values in Healthy Individuals in the First Six Decades.","authors":"Gülhan Kılıçarslan, Yeliz Gül","doi":"10.1002/jcu.70058","DOIUrl":"https://doi.org/10.1002/jcu.70058","url":null,"abstract":"<p><strong>Purpose: </strong>Following the advent of ultrasound elastography, the thyroid gland has been the subject of extensive research. Many studies have been conducted on diseases associated with the thyroid gland; however, relatively few studies have examined the elastography of normal thyroid tissue. This study aimed to calculate and compare thyroid elastography values in healthy individuals of all ages.</p><p><strong>Methods: </strong>In this study, the thyroid tissue and laboratory data of 687 volunteers were evaluated. The study population comprised 357 healthy individuals with normal ultrasound images and laboratory values. These individuals were divided into decades. Six groups were formed. The measurements included only thyroid tissue to prevent the formation of artifacts. The elastography evaluation was performed separately for the right lobe and left lobe, and the mean values were calculated. The data from each group were then compared with the data from the other groups via the Kolmogorov-Smirnov test.</p><p><strong>Results: </strong>The mean strain index, calculated without the use of age-related discrimination, was 1.05 ± 0.56 for the right lobe, 1.00 ± 0.41 for the left lobe, and 1.02 ± 0.39 for both lobes. The mean values for each decade were subsequently calculated, and the data of the groups were compared. The investigation revealed no statistically significant differences between the groups.</p><p><strong>Conclusion: </strong>Consequently, there was no substantial alteration in thyroid stiffness with advancing age. Therefore, it was concluded that age could be ignored when groups are created in future studies.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145053708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-Based Diagnosis and Postoperative Evaluation of Extrahepatic Portal Vein Obstruction in Pediatric Patients: A Case Report.","authors":"Xinmei Yan, Zhongtao Bao, Ling Chen","doi":"10.1002/jcu.70034","DOIUrl":"https://doi.org/10.1002/jcu.70034","url":null,"abstract":"<p><p>Ultrasound is vital for diagnosing and monitoring noncirrhotic extrahepatic portal vein obstruction in children, though literature on its use remains limited. This case report described the diagnostic and therapeutic processes in an 11-year-old child with recurrent hematochezia. Following the diagnosis based on clinical presentation and complementary investigations, the patient underwent surgical intervention. Postoperative follow-up was conducted using conventional ultrasound to assess the prognosis. This report may enhance sonographers' understanding of this rare disease, improve its early detection rate, and highlight the indispensable role of ultrasonography in long-term postoperative management.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between the Aortic Angle of the Right Coronary Artery and the Bifurcation Angle of the Left Main Coronary Artery With Coronary Artery Disease.","authors":"Murat Kaya, Osman Konukoğlu, Barış Can Arslan, Candan Güngör","doi":"10.1002/jcu.70059","DOIUrl":"https://doi.org/10.1002/jcu.70059","url":null,"abstract":"<p><strong>Background: </strong>The literature contains a few studies that explore the possibility of assessing coronary artery disease (CAD) risk based on the angle between the coronary arteries and the bifurcation of the aorta.</p><p><strong>Purpose: </strong>To reveal the relationship between the angle of the right coronary artery and the aorta, as well as the bifurcation angle of the left main coronary artery, with the degree of plaque and stenosis in the right coronary artery, left main coronary artery, left anterior descending artery (LAD), and circumflex artery (Cx).</p><p><strong>Materials and methods: </strong>The coronary CT angiographies of 217 patients, taken due to suspected CAD at our institution between October 2023 and June 2024, were retrospectively evaluated. All CT images were analyzed at different times by two experienced radiologists using a specialized workstation. There was significant concordance between intraobserver and interobserver assessments. Multiplanar reconstruction (MPR) was performed to measure the angles.</p><p><strong>Results: </strong>The mean LAD-Cx angle measured by the first radiologist was 78.81 ± 30.54, while the second radiologist's measurement was 79.34 ± 30.62, demonstrating excellent agreement. The mean right coronary artery-aortic (RCA-Aortic) angle measured by the first radiologist was 96.21 ± 33.47, while the second radiologist's measurement was 96.75 ± 33.62, again demonstrating excellent agreement.</p><p><strong>Conclusion: </strong>In this study, no association was found between coronary artery angles and the presence of plaque or stenosis. Therefore, coronary artery angles should not be considered a reliable indicator of CAD risk. Instead, risk assessment should include other well-established risk factors.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carotid Duplex Ultrasound Can Effectively Detect Ulcerative Plaques: A Single Center Exploratory Study.","authors":"Lianlian Zhang, Haiyang Qian, Lili Pan, Su Ai, Guofu Shi","doi":"10.1002/jcu.70066","DOIUrl":"https://doi.org/10.1002/jcu.70066","url":null,"abstract":"<p><strong>Purpose: </strong>Vulnerable plaque is closely associated with the occurrence of ischemic stroke. Our study aims to evaluate the diagnostic efficiency of carotid duplex ultrasound (CDU) in assessing vulnerability and vulnerability-related components of carotid plaques.</p><p><strong>Methods: </strong>We retrospectively and consecutively enrolled 127 patients and used high resolution magnetic resonance imaging (HRMRI) as the non-invasive \"gold standard\" based on CDU examinations, using vulnerable scores to assess the nature of plaques and comparing the results.</p><p><strong>Results: </strong>CDU and HRMRI have highly consistent results in assessing the nature of carotid plaques and the degree of carotid artery stenosis. With the increase in the degree of stenosis, the consistency between the two methods in evaluating the severity of stenosis is further enhanced. Notably, CDU and HRMRI demonstrate a particularly high level of agreement in characterizing the nature of carotid plaques, especially ulcerative plaques.</p><p><strong>Conclusion: </strong>The results indicate that CDU is an effective and non-invasive method for assessing the vulnerability of atherosclerotic plaques, particularly ulcerative plaques in real time. This provides a basis for stratified management and individualized diagnosis and treatment of patients.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Ultrasonographic Features Among Healthy Individuals and Patients With Trigger Finger.","authors":"Gizem Kılınç Kamacı, Yasin Demir, Gökcan Okur, Hatice Ceylan, Hatice Çetintürk, Şahide Eda Artuç, Umay Ekinci, Ümüt Güzelküçük, Koray Aydemir","doi":"10.1002/jcu.70080","DOIUrl":"https://doi.org/10.1002/jcu.70080","url":null,"abstract":"<p><strong>Purpose: </strong>The trigger finger is one of the leading causes of finger pain and triggering. The flexor tendons are stabilized by a fibrous band called the annular pulley. The first annular pulley (A1 pulley) is located at the level of the metacarpophalangeal joint. Trigger finger is characterized by thickening of the A1 pulley. There is a lack of clinical and ultrasonographic risk factors that may help clinicians. The main purpose of the study was to measure the thickness of the flexor tendon and A1 pulley in patients with trigger finger compared to healthy volunteers and to reveal risk factors of trigger finger.</p><p><strong>Methods: </strong>The study included 30 healthy volunteers and 30 patients with trigger fingers. The thickness of the flexor tendon and A1 pulley were measured using ultrasound. Multiple regression analysis was also conducted.</p><p><strong>Results: </strong>In the healthy group, the mean thickness of the flexor tendon and A1 pulley were 3.21 ± 0.64 and 0.40 ± 0.09 mm, respectively. In the TF group, the mean thickness of the flexor tendon and A1 pulley were 3.78 ± 0.86 and 0.49 ± 0.16 mm, respectively. The differences were statistically significant (p = 0.010 and p = 0.009, respectively). The mean thickness of the flexor tendon and A1 pulley of trigger finger were significantly higher than adjacent and contralateral healthy digits of the patients with trigger finger (p = 0.001, p = 0.001, p = 0.019, p = 0.002, respectively). The risk of trigger finger was found to be 11.5 times higher in diabetic patients, 3.734 times higher in patients with a history of hand forcing, 2.912 times with a 1 mm increase in flexor tendon thickness, and 1.724 times with an increase of 0.1 mm in A1 pulley thickness.</p><p><strong>Conclusions: </strong>In this study, the flexor tendon and A1 pulley were found to be more thickened in the trigger finger group compared to the controls. Diabetes mellitus, history of hand forcing, increased tendon, and A1 pulley thickness are among the risk factors associated with trigger finger.</p><p><strong>Trial registration: </strong>Ultrasound Features of Trigger Finger, Registry number: NCT05675488.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Cytomegalovirus Infection With Pulmonary Hypoplasia Secondary to Massive Ascites and Oligohydramnios: A Case Report.","authors":"Yoshiho Masui, Kazunori Iwasaki, Kei Hirabayashi, Kei Takehara, Aki Kamo, Mitsuhisa Shinya, Takakazu Kawamura, Hiroko Konno, Takeshi Murakoshi","doi":"10.1002/jcu.70055","DOIUrl":"https://doi.org/10.1002/jcu.70055","url":null,"abstract":"<p><p>A woman, gravida 5, para 3, presented with fetal ascites at 19 weeks of gestation. Urinary ascites was initially suspected because of massive ascites and oligohydramnios; however, biochemical analysis of fetal ascites was inconsistent with this diagnosis. A peritoneal-amniotic shunt was placed to prevent pulmonary hypoplasia. Postoperative bladder filling ruled out urinary ascites. At 28 weeks, findings suggestive of congenital cytomegalovirus (cCMV) infection emerged. The fetus was delivered at 29 weeks of age due to fetal distress and was diagnosed with cCMV by PCR. The neonate died 7 days after the gastrointestinal perforation.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When a Scrotal Mass Is More Than It Seems: A Case of Pediatric Paratesticular Rhabdomyosarcoma and Review of the Literature.","authors":"Maria Escolino, Mauro Porcaro, Maria Sofia Caracò, Claudia Di Mento, Giovanni Esposito, Giuseppe Maria Milano, Chiara Mignogna, Ciro Esposito","doi":"10.1002/jcu.70081","DOIUrl":"https://doi.org/10.1002/jcu.70081","url":null,"abstract":"<p><p>Paratesticular rhabdomyosarcoma (RMS) is a rare pediatric malignancy often misdiagnosed as benign conditions like epididymitis. We report a 4-year-old boy with paratesticular RMS and retroperitoneal metastasis, initially mistaken for epididymitis. The diagnostic delay resulted in disease progression, necessitating radical inguinal orchiectomy, hemiscrotectomy, and complete multimodal therapy. Literature review identified nine similar misdiagnosed pediatric cases due to atypical presentation. Despite a generally favorable prognosis, early diagnosis, radical orchiectomy, and multidisciplinary management are essential to reduce morbidity and improve survival outcomes in children with paratesticular RMS. Clinicians should consider RMS in children with persistent or atypical scrotal masses to avoid treatment delays.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}