Klemens Paul Kaiser, Tyll Jandewerth, Petra Davidova, Thomas Kohnen
{"title":"Surgical implications in intraocular lens exchange with an open posterior capsule: a retrospective case series and review of the literature.","authors":"Klemens Paul Kaiser, Tyll Jandewerth, Petra Davidova, Thomas Kohnen","doi":"10.1097/j.jcrs.0000000000001604","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001604","url":null,"abstract":"<p><strong>Purpose: </strong>To determine characteristics and differences in intraocular lens (IOL) exchange between eyes with an open (OPC) and closed posterior capsule (CPC).</p><p><strong>Setting: </strong>Department of Ophthalmology, Goethe-University, Frankfurt, Germany.</p><p><strong>Design: </strong>Retrospective case series and review of literature.</p><p><strong>Methods: </strong>Charts of all cases of IOL exchange between January 2010 and May 2024 were retrospectively reviewed. Main outcome measures were indications for surgery, IOL implantation technique, and the necessity of anterior vitrectomy. MEDLINE database and Google scholar were used to identify relevant past publications.</p><p><strong>Results: </strong>We included 37 eyes of 30 patients with a mean age of 62.1 ± 10.2 years, with 16 eyes (43.2%) with OPC undergoing IOL exchange. Mean interval between IOL implantation and IOL exchange was 61.50 ± 62.00 months in the OPC group and 15.81 ± 15.03 months in the CPC group. The most common indication was optical phenomena in 18 cases (48%). In the OPC group, intraoperative anterior vitrectomy was necessary twice as often (OPC nine cases (56%) vs. CPC five cases (24%)). Bag-to-bag IOL exchange was performed in all eyes with CPC, and in 10/16 (62%) with OPC (p=0.009). Postoperative complications were seen in a total of 7/16 eyes (43.7%) with OPC and 3/21 (14.3%) with CPC (p=0.012).</p><p><strong>Conclusion: </strong>The success rate of repositioning an IOL within a bag with OPC is less than that achieved with CPC. A vitrectomy is typically required when attempting a bag-to-bag IOL exchange with an OPC. Capsulotomy should only be performed if the necessity of an IOL exchange is unlikely.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Wang, Hendrik Burwinkel, Nicolas Bensaid, Douglas D Koch
{"title":"Evaluation of an artificial intelligence-based intraocular lens calculator: AI-based IOL-optimized formula.","authors":"Li Wang, Hendrik Burwinkel, Nicolas Bensaid, Douglas D Koch","doi":"10.1097/j.jcrs.0000000000001603","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001603","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the ZEISS AI IOL Calculator (ZEISS AI) and compare its accuracy in refractive prediction to the Barrett Universal II (BUII) and Kane formulas.</p><p><strong>Setting: </strong>Cullen Eye Institute, Baylor College of Medicine, Houston, TX.</p><p><strong>Design: </strong>Retrospective case series.</p><p><strong>Methods: </strong>The ZEISS AI IOL Calculator (ZEISS AI) is an artificial intelligence (AI) based IOL-optimized formula. The refractive prediction errors (PEs) were calculated in the entire dataset and subgroups of short eyes (axial length (AL) ≤ 22.5 mm) and long eyes (AL ≥ 25.0 mm). The standard deviation (SD), root-mean-square absolute error (RMSAE), mean absolute error (MAE), median absolute error (MedAE), and percentage of eyes within ±0.25 D, ±0.50 D, ±0.75 D, and ±1.00 D of PEs were calculated. Values with ZEISS AI were compared to those from Barrett Universal II (BUII) and Kane. Advanced statistical methods were applied using R.</p><p><strong>Results: </strong>A dataset of 10,838 eyes was included. Compared to ZEISS AI, BUII produced significantly greater SDs, RMSAEs, and MAEs in the whole group and short eyes, and the Kane had greater SD, RMSAE, and MAE in short eyes (all adjusted P<0.05); the BUII had significantly lower percentages of eyes within ±0.50 D of PEs in the whole group (80.0% vs 81.2%) and in short eyes (71.3% vs. 76.1%), and the Kane had lower percentage of eyes within ±0.50 D of PEs in short eyes (71.9% vs. 76.1%) (all adjusted P<0.05).</p><p><strong>Conclusion: </strong>The ZEISS AI IOL Calculator had superior performance compared to the BUII and Kane formulas, especially in short eyes.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of accuracy and axial length acquisition success rate by three types of swept-source OCT-based biometers.","authors":"Yukihito Kato, Masahiko Ayaki, Yoshiki Tanaka, Akeno Tamaoki, Yukihiro Sakai, Kei Ichikawa, Kazuo Ichikawa","doi":"10.1097/j.jcrs.0000000000001601","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001601","url":null,"abstract":"<p><strong>Purpose: </strong>To compare three biometers equipped with swept-source optical coherence tomography (OCT), including ARGOS (OCTB1), IOLMaster 700 (OCTB2), and Anterion (AS-OCTB). The primary aim was to assess the axial length (AL) acquisition success rates, and secondary aims included comparing parameters obtained from the three devices and evaluating postoperative refractive prediction errors.</p><p><strong>Setting: </strong>Chukyo Eye Clinic, Nagoya, Japan.</p><p><strong>Design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>The study included patients undergoing preoperative assessments for cataract surgery using the three biometers. The AL acquisition success rates and parameters obtained from the three devices were compared and the postoperative refractive prediction errors (defined as the difference between subjective refractive error and predicted refractive error) were assessed at one month after surgery.</p><p><strong>Results: </strong>The study included 361 eyes from 361 patients. The AL acquisition success rates for all patients were 100.0% (n=361) (OCTB1), 98.6% (n=356) (OCTB2), and 96.7% (AS-OCTB) (P < .0001), and those for nuclear sclerosis of grade 4 or higher were 100.0%, 87.8%, and 87.8%, respectively (P = .007). The AL of mature cataract was measurable only with OCTB1 using the enhanced retina visualization mode. Although there were significant differences in parameters obtained on the three devices, there were no significant differences in postoperative refractive prediction errors.</p><p><strong>Conclusions: </strong>OCTB1 demonstrated the highest AL acquisition success rate and was able to measure AL even in eyes with dense or mature cataract. AS-OCTB using a wavelength of 1300 nm showed lower AL acquisition success rates compared to the other two devices probably due to reduced light transmission through the vitreous body.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ehsan Sadri, Anthony Verachtert, Gregory D Parkhurst, Julio Echegoyen, Ifat Klein, Yael G Agmon, Gregg J Berdy
{"title":"Effectiveness and safety of a thermo-mechanical action device versus thermal pulsation device in the treatment of meibomian gland dysfunction.","authors":"Ehsan Sadri, Anthony Verachtert, Gregory D Parkhurst, Julio Echegoyen, Ifat Klein, Yael G Agmon, Gregg J Berdy","doi":"10.1097/j.jcrs.0000000000001602","DOIUrl":"10.1097/j.jcrs.0000000000001602","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the safety and effectiveness of thermo-mechanical action (Tixel C, Novoxel) compared with thermal pulsation (LipiFlow, Johnson & Johnson) in meibomian gland dysfunction (MGD).</p><p><strong>Setting: </strong>Private clinics and University clinic, USA.</p><p><strong>Design: </strong>Prospective, randomized (1:1), evaluator-masked, multicenter study.</p><p><strong>Methods: </strong>Subjects with Ocular Surface Disease Index (OSDI) between 23 and 79, fluorescein tear break-up time (TBUT) <10 s and Meibomian Gland Score (MGS) ≤12 in each eye received bilateral thermo-mechanical action (TMA) or thermal pulsation (TP). The treatment consisted of three sessions, two weeks apart, for TMA and one session for TP. TBUT, OSDI, MGS, and corneal and conjunctival staining (CCS) were assessed at baseline and at Weeks 4 and 12 post-last treatment session. The primary effectiveness endpoint was change in TBUT at Week 4.</p><p><strong>Results: </strong>Among the 106 treated subjects (N=53 per group), TBUT improved significantly (p<0.001) by 3.0±3.2 and 3.1±4.3 seconds after TMA and 2.7±2.7 and 3.3±3.6 seconds after TP, at Week 4 and Week 12, respectively. The change in TBUT for TMA was non-inferior to TP (linear mixed-effects model, p<0.001). OSDI, MGS and CCS significantly improved from baseline (p<0.001), with no significant between-group differences (p>0.05). OSDI improved by 26.4±21.1 and 28.6±22.4 after TMA and 18.8±21.0 and 21.9±18.5 after TP, at Week 4 and Week 12, respectively. No device-related adverse event occurred in either group.</p><p><strong>Conclusion: </strong>TMA safely and effectively improved clinical signs and symptoms of evaporative dry eye disease associated with MGD over a 12-week period, comparable to TP.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bianca N Susanna, Adriana S ForsetoMD, Aline M SilveiraMD, Marcony R Santhiago, Fernanda N Susanna, Nicolas C Pereira
{"title":"Femtosecond Laser- Assisted Customized CAIRS In Keratoconus Patients After ICRS Explantation: A Prospective Case Series: Customized CAIRS in post ICRS extrusion keratoconus patients.","authors":"Bianca N Susanna, Adriana S ForsetoMD, Aline M SilveiraMD, Marcony R Santhiago, Fernanda N Susanna, Nicolas C Pereira","doi":"10.1097/j.jcrs.0000000000001600","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001600","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effectiveness and safety of customized femtosecond laser-assisted corneal allogenic intrastromal ring segments (CAIRS) implantation in keratoconus patients with a history of intrastromal corneal ring segment (ICRS) explantation.</p><p><strong>Setting: </strong>Sorocaba Eye Hospital (Hospital Oftalmológico de Sorocaba - HOS), Sorocaba, Brazil.</p><p><strong>Design: </strong>Prospective case series.</p><p><strong>Methods: </strong>We included eight keratoconus patients with stable disease and with history of ICRS explantation at least six months before the inclusion in the study. Patients were excluded if presenting any other ocular pathology. Customized CAIRS was produced and implanted using femtosecond laser LDV Z8 (Ziemer Ophthalmic Systems AG, Port, Switzerland). Patients were followed-up for six months.</p><p><strong>Results: </strong>The mean reduction of the maximum, mean, and steep central keratometry was 3.03 ± 1.35 diopters (D) (p =0.01), 2.88 ± 2.51 D (p=0.02), and 2.41 ± 2.72 D (p=0.04), respectively. The mean spherical equivalent and refractive astigmatism reduced 6.28 ± 2.71 D (p =0.01), and 1.62 ± 2.83 D (p=0.16). All eyes, but one gained two or more lines of best spectacle corrected visual acuity (BSCVA).Additionally, five patients achieved a BSCVA of 20/40 or better. No intra or post-operative complications were observed.</p><p><strong>Conclusions: </strong>Customized femtosecond laser assisted CAIRS may be an effective and safe option for visual rehabilitation in keratoconus patients with previous ICRS explantation.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cataract Surgery and Intraocular Lens Implantation in Aviation Pilots.","authors":"João Mendes, Filomena J Ribeiro","doi":"10.1097/j.jcrs.0000000000001594","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001594","url":null,"abstract":"<p><p>The rising age of pilots and the extension of retirement age underscore the importance of investigating Presbyopia correction intraocular lenses during cataract surgery for Aviation Pilots. This study aims to assess recommendations from aviation regulatory agencies, providing guidance on the use of multifocal intraocular lenses in both commercial and military pilots. A review analysed the perspectives of aviation regulatory agencies regarding the implantation of multifocal intraocular lenses in pilots. Findings reveal a lack of consensus among agencies regarding the use of multifocal intraocular lenses. Some adopt a permissive stance, permitting their use, while others maintain restrictive approaches. Variations in the post-cataract surgery unfit assessment period were observed, ranging from six to twelve weeks. The implantation of multifocal intraocular lenses in aviation pilots remains contentious. Further research is crucial to address unresolved aspects associated with using multifocal intraocular lenses in this context.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Harold Ridley and the Invention of the Intraocular Lens: a Reappraisal.","authors":"Robert K Maloney, Sloan Mahone","doi":"10.1097/j.jcrs.0000000000001591","DOIUrl":"10.1097/j.jcrs.0000000000001591","url":null,"abstract":"<p><strong>Abstract: </strong>Harold Ridley permanently implanted the first intraocular lens (IOL) in 1950. The widely accepted narrative is that Ridley and his invention received a hostile reception from Stewart Duke-Elder and other ophthalmic thought leaders. Ridley suffered greatly but was eventually vindicated as later IOL designs were widely accepted. This narrative casts Ridley as a prophetic innovator who suffered and eventually triumphed against the forces of animosity, jealousy and close-mindedness arrayed against him. We argue that this narrative is biased because it was told by Ridley himself and amplified by his biographer and close friend, David Apple. There were good reasons to be skeptical of Ridley's invention. Ridley had not done pre-clinical studies, so his first patients suffered avoidable complications. He worked in secret at a time when openness was the norm. Ridley's IOL had a high percentage of poor outcomes. The cautious approach that Duke-Elder and others had towards IOLs is understandable. The accurate history is a story of a clash of worldviews between an inventor who was focused on innovating quickly to solve a major clinical problem and established leaders who were concerned about the harm to patients from a flawed invention. The skepticism of established thought leaders remains a valuable check on aggressive innovation today.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Morgan Micheletti, Matthew Brink, Jacob W Brubaker, Deborah Ristvedt, Steven R Sarkisian
{"title":"Standalone interventional glaucoma: evolution from the combination-cataract paradigm.","authors":"J Morgan Micheletti, Matthew Brink, Jacob W Brubaker, Deborah Ristvedt, Steven R Sarkisian","doi":"10.1097/j.jcrs.0000000000001537","DOIUrl":"10.1097/j.jcrs.0000000000001537","url":null,"abstract":"<p><p>One of the most impactful recent developments in the glaucoma community has been the concept of interventional glaucoma. In brief, this paradigm shift involves proactive rather than reactive intervention to address glaucoma earlier in the disease process, including in both standalone and combination-cataract settings. By intervening earlier with minimally invasive surgical, laser, or drug-delivery treatments instead of prolonged topical medications, interventional glaucoma aims to take the burden of medication compliance off the patient. It also allows for standalone surgical interventions rather than letting cataract surgery dictate the glaucoma treatment plan. This interventional mindset has been made possible by the increasing diversity and availability of effective minimally invasive treatment options. With these options as a springboard, it is time to reevaluate and advance the traditional glaucoma treatment paradigm.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"1284-1290"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Our Appreciation.","authors":"","doi":"10.1097/j.jcrs.0000000000001559","DOIUrl":"10.1097/j.jcrs.0000000000001559","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":"50 12","pages":"e1-e4"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William F Wiley, Alice T Epitropoulos, Jeffrey Whitman, Eva Liang, Ehsan Sadri, George Lau
{"title":"Rotational stability and visual performance of aberration-free, hydrophobic acrylic monofocal toric intraocular lens with enhanced material.","authors":"William F Wiley, Alice T Epitropoulos, Jeffrey Whitman, Eva Liang, Ehsan Sadri, George Lau","doi":"10.1097/j.jcrs.0000000000001540","DOIUrl":"10.1097/j.jcrs.0000000000001540","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the rotational stability and visual performance of the enVista toric intraocular lens (IOL) (MX60ET) in cataract patients with preexisting astigmatism.</p><p><strong>Setting: </strong>6 U.S. sites.</p><p><strong>Design: </strong>Prospective, multicenter.</p><p><strong>Methods: </strong>Cataract patients 18 years and older with preexisting astigmatism (0.77 to 4.53 diopters [D]) underwent phacoemulsification and implantation of enVista toric IOL (MX60ET). Outcome measures were the proportion of patients with absolute IOL axis rotation of ≤5 degrees, uncorrected and corrected distance visual acuities (UDVA and CDVA) at 4 m, uncorrected intermediate visual acuity (UIVA) at 66 cm, manifest refraction, and adverse events. The patients were followed up on days 1 to 2, 7 to 14, 30 to 60, and 120 to 180.</p><p><strong>Results: </strong>Mean astigmatism of 101 eyes (101 patients) reduced from 1.47 ± 0.64 D preoperatively to 0.38 ± 0.38 D at days 120 to 180 ( P < .001), with 88.1% (N = 89/101) of eyes achieving astigmatism within 0.75 D. Mean postoperative UDVA and UIVA were 0.10 ± 0.16 and 0.25 ± 0.15 logMAR, respectively. While 79.2% (N = 80/101) of patients had postoperative UDVA of 20/32 or better, 63.9% (N = 62/97) had UIVA of 20/40 or better. The mean toric IOL rotation from the operative visit to days 30 to 60 was 1.97 ± 2.06 degrees, with 97.4% (N = 74/76) of eyes showing toric IOL rotation of 5 degrees or less.</p><p><strong>Conclusions: </strong>The enhanced enVista toric IOL (MX60ET) demonstrated excellent rotational stability and astigmatic outcomes indicating good efficacy of the IOL for the correction of astigmatism during cataract surgery.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"1236-1241"},"PeriodicalIF":2.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}