{"title":"Photorefractive keratectomy in keratoconus: long-term outcomes from a precrosslinking era cohort.","authors":"Gustavo E Tamayo, Natalia Moros, Eduardo J Polania-Baron, Claudia Castell, Pilar Vargas","doi":"10.1097/j.jcrs.0000000000002047","DOIUrl":"10.1097/j.jcrs.0000000000002047","url":null,"abstract":"<p><strong>Purpose: </strong>To describe long-term visual, refractive, and topographic outcomes after photorefractive keratectomy (PRK) in patients with keratoconus treated before corneal crosslinking (CXL) became available.</p><p><strong>Setting: </strong>Single private ophthalmic center in Bogotá, Colombia.</p><p><strong>Design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>1532 archived paper charts from all patients at the practice between 1996 and 2004 were screened. Patients with keratoconus who underwent PRK using multiple excimer laser techniques, with adequate preoperative documentation and availability for re-evaluation after ≥20 years, were included. Outcomes included uncorrected (UDVA) and corrected (CDVA) distance visual acuity, refractive spherical equivalent, astigmatism, and keratometry.</p><p><strong>Results: </strong>68 patients with keratoconus treated with PRK were identified; 16 patients (29 eyes) with available long-term follow-up were included (mean follow-up of 22 years). UDVA improved from 0.81 ± 0.50 to 0.46 ± 0.36 logMAR ( P = .005) and CDVA from 0.14 ± 0.17 to 0.08 ± 0.11 logMAR ( P = .02), although not significant after excluding eyes that later required keratoplasty. Spherical equivalent decreased by 1.51 diopters (D) ( P = .001) and astigmatism by 0.82 D ( P = .03). Maximum keratometry showed no significant change ( P = .19). 4 eyes (13.8%) required keratoplasty, including 3 of 7 (43%) with advanced disease. The remaining 25 eyes (86.2%) did not require keratoplasty, although some required additional interventions.</p><p><strong>Conclusions: </strong>In this small pre-CXL cohort, mild-to-moderate keratoconus eyes had visual and refractive improvement, while keratoplasty was required mainly in advanced cases. These findings offer historical observational context rather than evidence of safety or efficacy.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcelo Ramos, Lucas M Barbosa, Sofia de Melo Ramos, Luisa de Melo Ramos, Jhonattan Rodrigues Garcia Costa, João Vítor de Mattos, Wilson Takashi Hida
{"title":"Antibiotic Injection in Cataract Surgery and Risk of Endophthalmitis: A Bayesian Meta-Analysis.","authors":"Marcelo Ramos, Lucas M Barbosa, Sofia de Melo Ramos, Luisa de Melo Ramos, Jhonattan Rodrigues Garcia Costa, João Vítor de Mattos, Wilson Takashi Hida","doi":"10.1097/j.jcrs.0000000000002045","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002045","url":null,"abstract":"<p><strong>Topic: </strong>Cataract surgery is the most performed surgical procedure worldwide, with over 28 million cases annually. Traditional postoperative care relies on topical eye drops for infection prevention and inflammation control; however, challenges such as patient noncompliance and cost limitations persist. The dropless cataract surgery approach, involving intracameral or subconjunctival administration of antibiotics and corticosteroids during surgery, has gained attention as an alternative to improve adherence, simplify care, and potentially reduce postoperative complications, including endophthalmitis.</p><p><strong>Clinical relevance: </strong>To evaluate the risk of postoperative endophthalmitis associated with antibiotic injection during cataract surgery in comparison to the standard eye drop regimen.</p><p><strong>Methods: </strong>We systematically searched PubMed, Embase, and the Cochrane Library for studies evaluating the safety of antibiotic injections in cataract surgery compared with conventional postoperative regimens. Bayesian random-effects meta-analysis was used for marginal posterior distributions for the overall and between-study heterogeneity, expressed as odds ratios (OR) with 95% credible intervals (CrIs). Risk of bias was assessed with ROBINS-I or RoB-2. All statistical analyses were performed using R version 4.5.0.</p><p><strong>Results: </strong>54 studies were included, encompassing 6,867,422 surgeries, of which 3,501,802 received antibiotic injection therapy. Antibiotic injection was associated with a reduction in the risk of postoperative endophthalmitis (OR 0.208; 95% CrI: 0.161-0.268), with a 100% posterior probability of clinically meaningful benefit (OR < 0.80) and a 99.1% likelihood that future studies would confirm these findings. Sensitivity analyses corroborated the general findings.</p><p><strong>Conclusion: </strong>The use of antibiotic injection was associated with a significant reduction in the risk of postoperative endophthalmitis.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of visual field outcomes after monofocal, bifocal, and trifocal intraocular lens implantation.","authors":"Shuangqing Yao, Fengjie Li, Jianing Shi, Xiaowei Zhong, Ranyi Ding, Mengdi Niu, Ying Zhang, Jijun Sun, Li Pei, Xiaozhen He, Jincong Wang, Mengqiu Zeng, Weiyun Shi, Ting Wang, Can Zhao","doi":"10.1097/j.jcrs.0000000000002041","DOIUrl":"10.1097/j.jcrs.0000000000002041","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the visual field (VF) outcomes after implantation of monofocal, bifocal, and trifocal intraocular lenses (IOLs) from the same manufacturer platform.</p><p><strong>Setting: </strong>Shandong Eye Hospital, Jinan, China.</p><p><strong>Design: </strong>Prospective, nonrandomized, controlled study.</p><p><strong>Methods: </strong>102 patients (123 eyes) with age-related cataract were divided into monofocal, bifocal, and trifocal IOL groups. Corrected distance visual acuity (CDVA), refraction, Humphrey 30-2 standard automated perimetry (SAP), and defocus curve were assessed preoperatively and 3 months postoperatively. Outcome measures included visual field index (VFI), mean deviation (MD), and pattern standard deviation (PSD), as well as regional mean sensitivity (MS) in 3 predefined VF regions: central (0 to 5 degrees, zone I), paracentral (6 to 15 degrees, zone II), and peripheral (16 to 30 degrees, zone III).</p><p><strong>Results: </strong>All 3 IOL groups showed significant postoperative improvements in CDVA, VFI, MD, PSD, and MS in all zones ( P < .05). Postoperative MS did not differ significantly among groups in zone I. In zone II, MS was higher in the bifocal and trifocal groups than in the monofocal group, with no significant difference between bifocal and trifocal IOLs. In zone III, MS was highest in the trifocal group, followed by the bifocal and monofocal groups ( P < .05). Intergroup differences in ΔMS were not significant in zone I but were greater in zone II for bifocal and trifocal IOLs. For zone III, ΔMS was significantly larger in the trifocal group than in the monofocal group.</p><p><strong>Conclusions: </strong>Postoperative VF sensitivity improved after all 3 IOL types. Central MS did not differ significantly among groups, whereas multifocal IOLs, particularly trifocal IOLs, showed higher MS in paracentral and peripheral zones.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rita Vought, Victoria Vought, John D Gelles, Frances Lai, Adam Zaki, Steven A Greenstein, Peter S Hersh
{"title":"Subjective patient perceptions of cataract and refractive surgery in an online forum.","authors":"Rita Vought, Victoria Vought, John D Gelles, Frances Lai, Adam Zaki, Steven A Greenstein, Peter S Hersh","doi":"10.1097/j.jcrs.0000000000002039","DOIUrl":"10.1097/j.jcrs.0000000000002039","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From earlier to updated quadrifocal intraocular lens designs: objective optical metrology analysis.","authors":"Eun Ah Jeong, Seung Pil Bang, Seth Pantanelli, Sujin Kang, Sonia H Yoo","doi":"10.1097/j.jcrs.0000000000002042","DOIUrl":"10.1097/j.jcrs.0000000000002042","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the optical performance of the Clareon PanOptix and Clareon PanOptix Pro intraocular lenses (IOLs) using interferometric metrology and identify measurable optical differences.</p><p><strong>Setting: </strong>Physiological Optics Laboratory, Daegu, South Korea.</p><p><strong>Design: </strong>Experimental optical-bench investigation.</p><p><strong>Methods: </strong>3 +20.0-diopter samples each of the PanOptix and PanOptix Pro IOLs were analyzed using a Mach-Zehnder interferometer in a model eye incorporating +0.27 μm corneal spherical aberration (SA). Microscopic imaging, wavefront reconstruction with Zernike analysis, diffractive-step profile reconstruction, point-spread function (PSF)-based retinal image simulation, halo analysis, and through-focus modulation transfer function (MTF) analysis were performed.</p><p><strong>Results: </strong>Both IOLs showed broadly similar diffractive architecture and SA profiles. Peak-to-valley step-profile amplitudes were comparable, although the PanOptix Pro showed localized differences in the reconstructed step-height contour. PSF-based analyses showed broadly similar focal behavior, but the PanOptix Pro demonstrated clearer Sloan F contour preservation and more evident central PSF-core brightness at the far-intermediate position. In through-focus average MTF (aMTF) profiles, the PanOptix Pro showed a modestly higher far-focus peak and a less pronounced post-peak dip, particularly at 4.5 and 3.0 mm pupils. MTF50 analysis showed a similar overall pattern, with greater variability and more apparent intermodel differences at larger pupil sizes.</p><p><strong>Conclusions: </strong>The PanOptix Pro preserves the fundamental design and SA profile of the original PanOptix while showing localized diffractive step-height modifications. Together with clearer far-intermediate F-image preservation, sustained central PSF-core brightness, and a shallower post-peak aMTF dip, these findings are consistent with a relative redistribution of optical energy toward the far-intermediate region, supporting greater far-intermediate optical continuity without substantial changes in nominal add power or overall focal structure.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Moro-Muniz, Jorge Hernández-Cerdá, David Salom-Alonso
{"title":"Sequential clinical images of anterior segment toxicity after intracameral methylene blue in cataract surgery.","authors":"Marta Moro-Muniz, Jorge Hernández-Cerdá, David Salom-Alonso","doi":"10.1097/j.jcrs.0000000000002037","DOIUrl":"10.1097/j.jcrs.0000000000002037","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giacomo Savini, Kenneth J Hoffer, Arianna Grendele, Catarina C P Coutinho, Gianluca Cappuccini, Domenico Schiano-Lomoriello
{"title":"Agreement between slitlamp retroillumination images and Scheimpflug retroillumination display for toric intraocular lens orientation.","authors":"Giacomo Savini, Kenneth J Hoffer, Arianna Grendele, Catarina C P Coutinho, Gianluca Cappuccini, Domenico Schiano-Lomoriello","doi":"10.1097/j.jcrs.0000000000002038","DOIUrl":"10.1097/j.jcrs.0000000000002038","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The European Society of Cataract and Refractive Surgeons Cataract Simulation Curriculum: Wet Lab and Virtual Reality Pathways to Competency.","authors":"Lida P Lalou, Sarah Maling","doi":"10.1097/j.jcrs.0000000000002036","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002036","url":null,"abstract":"<p><p>Cataract surgery training across Europe remains heterogeneous despite high procedural demand, and a harmonized simulation pathway is lacking. This Special Report proposes an ESCRS cataract simulation curriculum that national training bodies and educators can adapt to existing programmes. It synthesizes European training surveys, evidence on simulation-related performance and safety benefits, and European Society of Cataract and Refractive Surgery (ESCRS) educational infrastructure. The pathway comprises entry assessment, foundation skills, core phacoemulsification, complication management, supervised operating-room progression, and maintenance of competency. Progression is based on objective virtual reality (VR) metrics or structured wet-lab scoring combined with workplace-based assessments. Model-eye and VR modalities are mapped to complementary stages of training, and implementation is framed around national portfolio integration, regional hubs, the ESCRS Moving Simulator, sustainability metrics, and equity monitoring. A standardized but locally adaptable curriculum may improve readiness for live surgery, support maintenance of competency, and promote safer, more equitable cataract training.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Light adjustable lens results of spherical equivalent and astigmatism correction from the U.S. Food and Drug Administration postapproval study.","authors":"Ashith Tripathi, Sachitanand Singh","doi":"10.1097/j.jcrs.0000000000002034","DOIUrl":"10.1097/j.jcrs.0000000000002034","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply : Light adjustable lens results of spherical equivalent and astigmatism correction from the U.S. Food and Drug Administration postapproval study.","authors":"Jack T Holladay, Matt Haller","doi":"10.1097/j.jcrs.0000000000002035","DOIUrl":"10.1097/j.jcrs.0000000000002035","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}