{"title":"Prolonged Intralenticular Incarceration of the Ozurdex Implant.","authors":"Lili Zhang, Ting Zhang, Rui Jiang","doi":"10.1097/j.jcrs.0000000000002073","DOIUrl":"10.1097/j.jcrs.0000000000002073","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pratheeba Devi Nivean, Ruwa Jehza Nazar, Nivean Madhivanan
{"title":"Comments on \"Real world characteristics and safety outcomes of 10000 eyes treated with intracanalicular dexamethasone insert: IRIS registry analysis 2019 to 2021\".","authors":"Pratheeba Devi Nivean, Ruwa Jehza Nazar, Nivean Madhivanan","doi":"10.1097/j.jcrs.0000000000002071","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002071","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dilan Colak Arici, Seda Liman Uzun, Zelal Besaltı Ekinci, Sanem Belgin, Nilay Kandemir Besek, Ahmet Kırgız, Akif Ozdamar
{"title":"Ray-Tracing Aberrometry and the Dysfunctional Lens Index for Objective Assessment of Posterior Capsular Opacification.","authors":"Dilan Colak Arici, Seda Liman Uzun, Zelal Besaltı Ekinci, Sanem Belgin, Nilay Kandemir Besek, Ahmet Kırgız, Akif Ozdamar","doi":"10.1097/j.jcrs.0000000000002074","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002074","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the dysfunctional lens index (DLI), higher-order aberrations (HOA), and modulation transfer function (MTF) from ray-tracing aberrometry as objective markers of posterior capsular opacification (PCO) and treatment response.</p><p><strong>Setting: </strong>Two tertiary ophthalmology centers, Istanbul, Turkey.</p><p><strong>Design: </strong>Prospective interventional study with a clear-capsule pseudophakic control group.</p><p><strong>Methods: </strong>Eyes with visually significant PCO after uncomplicated phacoemulsification with monofocal IOL implantation underwent ray-tracing aberrometry and 4 weeks after Nd:YAG capsulotomy; one eye per patient was analysed. CDVA, DLI, total and internal HOA root mean square (RMS), Zernike components, and MTF at 5-30 cycles/degree (cpd) were compared with clear-capsule control eyes with the same IOL.</p><p><strong>Results: </strong>Thirty-one eyes of 31 patients (mean age 66.7 years; 21 female) and 28 control eyes were included. All parameters improved after capsulotomy (all P<.001): CDVA from 0.52 to 0.10 logMAR, DLI from 3.10 to 7.20, internal HOA RMS by 66.9%. Internal coma and trefoil decreased, whereas spherical aberration was unchanged (negative control). MTF improved at all six spatial frequencies. Pre-operatively, PCO eyes were degraded relative to controls (DLI 3.35 vs 7.67; P<.001); post-operatively they matched controls (7.23 vs 7.67; P=.44). DLI correlated with internal HOA (r=-0.947) and MTF (r=+0.842) but not CDVA (r=-0.051).</p><p><strong>Conclusions: </strong>Ray-tracing aberrometry offers an objective view of PCO-induced optical degradation. Because the DLI tracks internal aberrations and MTF yet remains independent of high-contrast acuity, it captures impairment that CDVA alone overlooks, and returns to clear-capsule levels after capsulotomy. The DLI thus serves as a useful adjunctive marker for gauging PCO-related degradation and monitoring treatment response.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahsaw Mansoor, Alice Jiang, Stephen Kwong, Hasan Alsetri, Samuel Masket, Nicole Fram
{"title":"Clinical and Refractive Outcomes of Secondary IOL Fixation Using Small-Incision Scleral Suture Fixation versus Intrascleral Haptic Fixation.","authors":"Mahsaw Mansoor, Alice Jiang, Stephen Kwong, Hasan Alsetri, Samuel Masket, Nicole Fram","doi":"10.1097/j.jcrs.0000000000002066","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002066","url":null,"abstract":"<p><strong>Purpose: </strong>To compare clinical and refractive outcomes of small-incision scleral suture fixation (SSF) versus intrascleral haptic fixation (ISHF) for secondary intraocular lens (IOL) implantation in adults.</p><p><strong>Setting: </strong>A single outpatient ophthalmology clinic.</p><p><strong>Design: </strong>Retrospective, single-center cohort study.</p><p><strong>Methods: </strong>Eyes undergoing small-incision SSF or ISHF between 2019 and 2024 were identified. Demographics, surgical indications, IOL types, refractive accuracy, and postoperative complications were analyzed. Refractive outcomes were evaluated using spherical equivalent refractive accuracy (SERA) and absolute SERA (ASERA).</p><p><strong>Results: </strong>A total of 132 eyes from 125 adult patients were included. Fifty-six eyes underwent SSF and 76 underwent ISHF. Indications included subluxated IOL (58%), dislocated IOL (17%), aphakia (20%), and uveitis-glaucoma-hyphema syndrome (5%). In the SSF group, MX60E or ET IOLs predominated, while CT Lucia 602 was most common in ISHF. Mean SERA was -0.45 D for SSF and -0.36 D for ISHF (p = 0.48); mean ASERA was 0.52 D and 0.54 D, respectively (p = 0.96). At postoperative month 3, 70% of SSF versus 62% of ISHF eyes were within ±0.50 D of target, and 85% versus 86% were within ±1.00 D. Complication rates were low and comparable, with trends toward higher early hypotony in SSF and more reoperations in ISHF.</p><p><strong>Conclusions: </strong>Both small-incision SSF and ISHF are safe and effective for secondary IOL implantation in adults. Refractive outcomes were comparable, with SSF demonstrating slightly greater predictability and fewer reoperations, while ISHF was associated with less early hypotony. Technique selection should be guided by surgeon experience, IOL choice, and patient-specific factors.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liliana Werner, Max Liu, Zoha N Mian, Ethan Driffill, Andrea Ortiz, Joshua Ong, J Morgan Micheletti
{"title":"Joint Assessment of Material Exposure in Space (JAMES): Laboratory analyses of intraocular lenses after low-Earth-orbit exposure on the exterior of the International Space Station.","authors":"Liliana Werner, Max Liu, Zoha N Mian, Ethan Driffill, Andrea Ortiz, Joshua Ong, J Morgan Micheletti","doi":"10.1097/j.jcrs.0000000000002069","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002069","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate effects of low Earth orbit (LEO) space conditions on intraocular lenses (IOLs) manufactured from different materials.</p><p><strong>Setting: </strong>International Space Station (ISS); Intermountain Ocular Research Center (John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA).</p><p><strong>Design: </strong>Experimental study.</p><p><strong>Methods: </strong>135 IOLs made of hydrophobic acrylic, hydrophilic acrylic, and silicone materials were launched to the ISS as pressurized cargo. Of these, 61 were analyzed. On the ISS, the IOLs were placed in 3 external locations, differentiated by their exposure conditions: Ram (high atomic oxygen flux), Zenith (filtered UV-channel exposure), and Underdeck (external ISS environment with partial shielding). 45 corresponding controls remained on Earth. Of these, 20 were analyzed. After 6 months, the flight IOLs returned to Earth; 61 flight IOLs and 20 controls underwent gross and light microscopy. Changes were further assessed through scanning electron microscopy coupled with elemental analyses or spectrophotometry.</p><p><strong>Results: </strong>Post-mission analysis of space-exposed IOLs demonstrated changes consistent with polymer erosion in 5 hydrophobic and 3 hydrophilic acrylic IOLs. 2 hydrophobic acrylic and 3 silicone lenses demonstrated yellow optic discoloration with changes in light transmission. These IOLs were all in the tray closest to exposure to Ram or Zenith conditions. All 6 space-exposed light-adjustable lenses (LALs; RxSight) in the 3 locations, with or without ActivShield, exhibited similar \"cobblestone\" changes on the anterior and posterior optic surfaces, as well as the optic edge.</p><p><strong>Conclusions: </strong>This exploratory study showed that IOL materials may differ in susceptibility to environmental hazards in LEO. These findings may inform packaging, shipping, and storage of IOLs in space, as ophthalmic care will be required for future long-duration space missions and eventual extraterrestrial habitation.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical outcomes of patients bilaterally implanted with the light adjustable lens: results of a phase IV clinical registry.","authors":"Julie M Schallhorn, Alekya Rajanala","doi":"10.1097/j.jcrs.0000000000001994","DOIUrl":"10.1097/j.jcrs.0000000000001994","url":null,"abstract":"<p><strong>Purpose: </strong>To report the outcomes of the light adjustable lens (LAL) collected from a clinical registry.</p><p><strong>Setting: </strong>Multiple private practices in the United States.</p><p><strong>Design: </strong>Multicenter prospective observational study.</p><p><strong>Methods: </strong>Patients who underwent bilateral LAL implantation and who had corrected distance visual acuity ≥20/20 -2 before lens adjustment were enrolled. Assessment was performed at one visit 1 to 3 months after final lock-in treatment.</p><p><strong>Results: </strong>A total of 1101 participants (2202 eyes) were included. Of these, 586 eyes had prior corneal refractive surgery (CRS) and 1616 had no prior CRS (No CRS). 12.3% of participants were targeted for bilateral emmetropia, 9.3% for bilateral near, and 78.4% for blended vision. Of eyes targeted for emmetropia, 81.2% achieved a uncorrected distance visual acuity (UDVA) of ≥20/20 (82.2% of No CRS and 78.4% of CRS). A total of 94.3% of eyes targeted for emmetropia had a manifest spherical equivalent (MSE) of ≤0.5 diopter (D) (94.7% of No CRS, 92.8% of CRS). The mean prediction error in MSE was -0.048 ± 0.366 D in No CRS and -0.016 ± 0.441 D in CRS. A total of 89% of patients with blended vision and 93% of patients with bilateral emmetropic target had binocular UDVA of ≥20/20. In the CRS group, 87% with blended vision and 87% with binocular emmetropia achieved binocular UDVA of ≥20/20. Binocular uncorrected near visual acuity of ≥J1 was achieved with blended vision in 85% of patients in the No CRS group and 82% of patients in the CRS group.</p><p><strong>Conclusions: </strong>In this multicenter study, patients achieved a high degree of precision with the LAL regardless of prior CRS.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"1015-1022"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13592823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David F Chang, Emily M Schehlein, Eliesa A Ing, Jacob D Grodsky, Cathleen M McCabe, Irene C Kuo
{"title":"Current practice patterns for cleaning tonometry tips and diagnostic or laser lenses.","authors":"David F Chang, Emily M Schehlein, Eliesa A Ing, Jacob D Grodsky, Cathleen M McCabe, Irene C Kuo","doi":"10.1097/j.jcrs.0000000000002007","DOIUrl":"10.1097/j.jcrs.0000000000002007","url":null,"abstract":"<p><p>In an online survey of >1000 ophthalmologists, most reported using alcohol wipes or swabs to clean tonometry tips (73%) and diagnostic (63%) or laser (50%) contact lenses. Use of disposable devices or high-level disinfection (HLD) was uncommon and driven largely by facility policies or regulatory requirements. Only 19% of those using HLD did so because they believed it to be safer. Ocular surface toxicity and device damage were commonly seen with HLD. Reports of infection transmission were exceedingly rare, with 99% indicating they had never encountered a case. More than 75% of respondents were strongly opposed, while only 3% strongly supported requiring HLD for tonometry tips and diagnostic or laser lenses. In the absence of evidence that common cleaning methods-such as alcohol wipes or soap and water-pose significant infection risk, the use of HLD for these routine devices should be left to the discretion of ophthalmologists.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"959-964"},"PeriodicalIF":3.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dilated Pupil Vertical-to-Horizontal Ratio as a Predictor of Intraoperative Floppy Iris Syndrome.","authors":"Haruka Kakiuchi, Shumpei Obata, Masahito Ohji, Osamu Sawada","doi":"10.1097/j.jcrs.0000000000002068","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002068","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate whether intraoperative floppy iris syndrome (IFIS) can be predicted from pupil morphology, including vertical pupil elongation and pupillary diameter.</p><p><strong>Setting: </strong>Shiga University of Medical Science Hospital, Shiga, Japan.</p><p><strong>Design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>Patients who underwent standalone phacoemulsification cataract surgery between November 2022 and April 2023 were retrospectively reviewed. In bilateral cases, only the first operated eye was included. Eyes with prior ocular surgery or conditions affecting pupil morphology were excluded. Surgical videos were reviewed to assess pupil morphology parameters, including the pupil vertical-to-horizontal ratio (PVHR) and the composite pupil-to-corneal diameter ratio (CPCDR) at the beginning of surgery, and to evaluate IFIS incidence. IFIS incidence was treated as the outcome variable. Explanatory variables comprised age, sex, hypertension, diabetes mellitus, α1-adrenergic antagonist use, and pupil morphology parameters. Associations were evaluated using logistic regression.</p><p><strong>Results: </strong>A total of 263 patients (263 eyes) were included, of which 23 eyes (8.7%) developed IFIS. PVHR was significantly higher in eyes with vs without IFIS (median: 1.06 vs 1.03; p < 0.001), while CPCDR was significantly lower (0.56 vs 0.70; p < 0.001). In the multivariable logistic regression analysis, PVHR (odds ratio: 4.06; p = 0.0005) and CPCDR (odds ratio: 0.43; p < 0.0001) were independently associated with IFIS.</p><p><strong>Conclusions: </strong>Vertical pupil elongation and poor dilation after pharmacologic mydriasis were independently associated with IFIS. Assessment of pupil shape, in addition to pupil size, may improve preoperative identification of eyes at risk for IFIS.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endothelial Cell Loss associated with Pseudo exfoliation.","authors":"Pragati Tiwari, Sunita Chaurasia","doi":"10.1097/j.jcrs.0000000000002067","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002067","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}