{"title":"Clinical Outcomes of Patients Bilaterally Implanted with the Light Adjustable Lens: Results of a Phase IV Clinical Registry.","authors":"Julie M Schallhorn, Alekya Rajanala","doi":"10.1097/j.jcrs.0000000000001994","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001994","url":null,"abstract":"<p><strong>Purpose: </strong>To report the outcomes of the Light Adjustable Lens (LAL) collected from a clinical registry.</p><p><strong>Setting: </strong>Multiple private practices in the United States.</p><p><strong>Design: </strong>Multi-center prospective observational study.</p><p><strong>Methods: </strong>Patients who underwent bilateral LAL implantation and who had best-corrected distance visual acuity (CDVA) ≥ 20/20-2 before lens adjustment were enrolled. Assessment was performed at one visit 1-3 months after final lock-in treatment.</p><p><strong>Results: </strong>A total of 1101 participants (2202 eyes) were included. Of these, 586 eyes had prior corneal refractive surgery (CRS) and 1616 had no prior CRS (No CRS). 12.3% of participants were targeted for bilateral emmetropia, 9.3% for bilateral near and 78.4% for blended vision. Of eyes targeted for emmetropia, 81.2% achieved a UDVA of >20/20 (82.2% of No CRS and 78.4% of CRS). A total of 94.3% of eyes targeted for emmetropia had a MSE of <0.5D (94.7% of No CRS, 92.8% of CRS). The mean prediction error in MSE was -0.048 ± 0.366D in No CRS and -0.016 ± 0.441D in CRS. A total of 89% of patients with blended vision and 93% of patients with bilateral emmetropic target had binocular UCVA of >20/20. In the CRS, group 87% with blended vision and 87% with binocular emmetropia achieved binocular UCVA of >20/20. Binocular UNVA of >J1 was achieved with blended vision in 85% of patients in the No CRS group and 82% of patients in the CRS group.</p><p><strong>Conclusions: </strong>In this multi-center study, patients achieved a high degree of precision with the LAL regardless of prior corneal refractive surgery.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sathish Srinivasan, Jai Kelkar, Aditya Kelkar, Hassan Khaled, Christina Grupcheva, Alek Topov, Silvia Stoyanova, Alexander Mordaunt, Richard Packard
{"title":"Efficacy and safety of aselective laser device to create centred capsulotomies in white intumescent cataracts: international multicentre study (LC-WIC study).","authors":"Sathish Srinivasan, Jai Kelkar, Aditya Kelkar, Hassan Khaled, Christina Grupcheva, Alek Topov, Silvia Stoyanova, Alexander Mordaunt, Richard Packard","doi":"10.1097/j.jcrs.0000000000001996","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001996","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and safety of a selective laser device (CAPSULaser, EXCEL- LENS, CA, USA) to create centred and circular anterior capsulotomies in eyes with white intumescent cataracts.</p><p><strong>Setting: </strong>International, multicentre, study across five clinical sites in the United Kingdom, Bulgaria, India and Saudi Arabia.</p><p><strong>Design: </strong>Prospective, multicentre interventional cohort study.</p><p><strong>Method: </strong>A total of 93 eyes of 91 subjects with white intumescent cataracts were recruited after anterior segment OCT (AS-OCT) established the presence of intralenticular fluid pockets indicative of raised intralenticular pressure. In all cases, prior to phacoemulsification, selective laser capsulotomy (SLC) was performed by staining the anterior capsule with a customised 0.4 % trypan blue solution. Capsulotomies were created with a diameter of 5.5 mm. Subjects were followed up at one day, one week, one and three months postoperatively.</p><p><strong>Results: </strong>In all cases, the capsulotomy was successfully created. No intraoperative complications were observed. At 3 months postoperatively the mean capsulotomy diameter measured 5.3 mm (range: 5.2 to 5.5 mm). No cases of capsular phimosis were observed during the three months follow-up. In all cases, visual acuity improved from preoperative light perception to mean postoperative uncorrected distance visual acuity (UDVA) of 0.28 LogMAR (range: 0.0 to 1.0).</p><p><strong>Conclusion: </strong>The use of SLC in this series of eyes with intumescent cataracts achieved consistently sized and well-centred capsular openings. There were no complications. These results highlight the precision and safety of using selective laser capsulotomy for creating anterior capsulotomies in white intumescent cataracts.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Use of intracameral antibiotics prophylaxis in patients with posterior capsular rupture during cataract surgery: systematic review and meta-analysis\".","authors":"Yin Jiang, Fei Jiang, Huiling Ye, Bei Chen","doi":"10.1097/j.jcrs.0000000000001985","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001985","url":null,"abstract":"<p><strong>Abstract: </strong>This commentary evaluates the systematic review assessing intracameral antibiotic prophylaxis in cataract surgery complicated by posterior capsular rupture. While pooled findings suggest reduced endophthalmitis risk, reliance on observational studies, heterogeneity in antibiotic agents, and limited patient-level data restrict causal interpretation. Prospective studies with standardized protocols are needed to guide optimal prophylactic strategies.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebastian T Lee, Tyler Whitaker, Stephen Christensen, Brian C Stagg, Judith E A Warner
{"title":"Incidence of Posterior Capsular Rupture in Routine and Complex Cataract Surgeries at a Major Training Institution.","authors":"Sebastian T Lee, Tyler Whitaker, Stephen Christensen, Brian C Stagg, Judith E A Warner","doi":"10.1097/j.jcrs.0000000000001991","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001991","url":null,"abstract":"<p><p>Reports on posterior capsular rupture (PCR) incidence in the US from the past decade are limited, and impact of trainee presence versus responsibility is unclear. We retrospectively analyzed a database of surgical complications within all cataract surgeries from 2022 to 2024 at the Moran Eye Center. PCR rates were stratified by case complexity and presence and direct responsibility of trainees. Among 14,240 cataract surgeries, the PCR rate was 0.67% (95% CI: 0.54-0.81%). PCR occurred more frequently in complex (1.4%) versus routine (0.5%) cases (p<0.001). In cases with PCR, 68% had vitreous loss and 34% reported anterior vitrector use. With assisting trainees present, PCR rate was elevated at 0.94% versus 0.23% without (p<0.001). When residents assisted, they caused PCR twice as often as attending physicians: 0.80% > 0.40% (p=0.03). Overall, up-to-date PCR incidence from a large academic center is provided. Case complexity and both trainee presence and responsibility significantly increased risk.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chaerim Kang, Angela S Zhu, T Michael Kashner, Thomas A Oetting, Patrick J Morhun, Paul B Greenberg
{"title":"An Investigation into the Low Use Rate of Immediate Sequential Bilateral Cataract Surgeries in the U.S.","authors":"Chaerim Kang, Angela S Zhu, T Michael Kashner, Thomas A Oetting, Patrick J Morhun, Paul B Greenberg","doi":"10.1097/j.jcrs.0000000000001992","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001992","url":null,"abstract":"<p><p>Extending an earlier paper, we investigated why immediate sequential bilateral cataract surgery (ISBCS) rates in the United States (US) are low. Data came from 44,295 bilateral cataract surgeries (BCS) in the US Department of Veterans Affairs (VA) between 2004 through 2023. Advanced analytics were used to estimate independent associations between clinical and non-clinical factors on ISBCS use rates both pre- and during the pandemic. The relative ISBCS use rate increased 231% with the pandemic independently of changes in other factors, though the absolute rate remained low (4%). Clinical factors decreasing ISBCS use rates (ocular comorbidity and facility BCS volume) became less important during the pandemic, while non-clinical factors (travel burden) increasing ISBCS use rates up become more important. Low use rates in the VA, where most physicians are salaried, come from surgeons and patients who act as if ISBCS pose substantive additional risk to safety and effectiveness.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David F Chang, Emily M Schehlein, Eliesa A Ing, Jacob D Grodsky, Cathleen M McCabe, Irene C Kuo
{"title":"Current practice patterns for cleaning tonometry tips and diagnostic/laser lenses.","authors":"David F Chang, Emily M Schehlein, Eliesa A Ing, Jacob D Grodsky, Cathleen M McCabe, Irene C Kuo","doi":"10.1097/j.jcrs.0000000000002007","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000002007","url":null,"abstract":"<p><strong>Abstract: </strong>In an online survey of >1000 ophthalmologists, most reported using alcohol wipes or swabs to clean tonometry tips (73%) and diagnostic (63%) or laser (50%) contact lenses. Use of disposable devices or high-level disinfection (HLD) was uncommon and driven largely by facility policies or regulatory requirements. Only 19% of those using HLD did so because they believed it to be safer. Ocular surface toxicity and device damage were commonly seen with HLD. Reports of infection transmission were exceedingly rare, with 99% indicating they had never encountered a case. More than 75% of respondents were strongly opposed, while only 3% strongly supported requiring HLD for tonometry tips and diagnostic or laser lenses. In the absence of evidence that common cleaning methods - such as alcohol wipes or soap and water - pose significant infection risk, the use of HLD for these routine devices should be left to the discretion of ophthalmologists.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raphael Kilian, Andrea Taloni, Valentino De Ruvo, Rossella Spena, Massimo Busin, Cristina Bovone
{"title":"Blepharoptosis after Modern Phacoemulsification Cataract Surgery: Incidence, Risk Factors and Underlying Mechanisms.","authors":"Raphael Kilian, Andrea Taloni, Valentino De Ruvo, Rossella Spena, Massimo Busin, Cristina Bovone","doi":"10.1097/j.jcrs.0000000000001997","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001997","url":null,"abstract":"<p><strong>Topic: </strong>This is a review of the available literature on blepharoptosis following modern phacoemulsification cataract surgery with intraocular lens (IOL) implantation.</p><p><strong>Clinical relevance: </strong>Blepharoptosis is a frequently underestimated complication of ocular surgery.</p><p><strong>Methods: </strong>This review followed PRISMA guidelines and was prospectively registered in PROSPERO (CRD420261348501). A literature search was conducted in PubMed/MEDLINE and the Cochrane Central Register of Controlled Trials, from database inception to February 2026. Studies evaluating postoperative ptosis after modern phacoemulsification with IOL implantation were included. Extracted data focused on the incidence of ptosis and associated risk factors.</p><p><strong>Results: </strong>Eight studies, including a total of 863 eyes, met the inclusion criteria. Five studies reported the exact incidence of ptosis, whereas the remaining studies only compared preoperative and postoperative marginal reflex distance 1 (MRD1). Among studies reporting incidence, rates ranged from 0%-10.7%, with four of the five studies (674/702 eyes, 96%) reporting incidences ≤4.1%. None of the studies comparing preoperative and postoperative MRD1 measurements found a statistically significant difference. Lower preoperative levator palpebrae superioris function and higher preoperative MRD1 were identified as potential risk factors. Conversely, surgical duration and lid speculum type were not consistently associated with ptosis. Studies using exclusively topical anaesthesia reported either no ptosis or no significant change in MRD1.</p><p><strong>Conclusion: </strong>Postoperative ptosis following modern cataract surgery has a low but not negligible incidence. Preoperative eyelid characteristics and the type of anaesthesia may influence its occurrence. Postoperative ptosis should be routinely discussed during preoperative counselling.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148271744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monovision versus Blended Vision for Presbyopia Correction: A Prospective Observational Study.","authors":"Faheem Raja, Nitin Vichare, Ankuj Tinna, Nikita Rajshree, Pragati Gaikwad","doi":"10.1097/j.jcrs.0000000000001993","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001993","url":null,"abstract":"<p><strong>Purpose: </strong>To compare visual outcomes, quality of life, and patient satisfaction between monovision with bilateral monofocal intraocular lenses (IOLs) and blended vision combining a trifocal IOL in the dominant eye with a monofocal IOL in the non-dominant eye for presbyopia correction after cataract surgery.</p><p><strong>Setting: </strong>Tertiary care Ophthalmology center in Mumbai, India.</p><p><strong>Design: </strong>Prospective observational study with masked outcome assessment.</p><p><strong>Methods: </strong>A total of 150 patients with bilateral cataracts who desired postoperative spectacle independence were counselled regarding two surgical strategies: monovision with bilateral monofocal IOLs or blended vision (trifocal IOL in the dominant eye and monofocal IOL in non-dominant eye). After detailed counselling, patients selected their preferred strategy. Outcomes were assessed at 6 months postoperatively.</p><p><strong>Results: </strong>At 6 months, the blended group demonstrated a significantly lower mean area under curve compared to the monovision group (0.746 ± 0.130 vs 1.090 ± 0.295 logMAR·D, respectively, p < 0.001), indicating broader depth of focus. NEI-VFQ25 score was significantly higher in the blended vision group (89.1 ± 9.8 vs 83.6 ± 10.8; p=0.001). Blended vision achieved better spectacle independence for distance, near and intermediate tasks. Stereoacuity was significantly better preserved in blended vision. Blended vision, however, was linked to higher incidence of halos and decreased contrast sensitivity in both photopic and mesopic conditions.</p><p><strong>Conclusions: </strong>Blended vision provides superior continuous range of vision, better quality of life, enhanced spectacle independence, and preserved stereoacuity compared to monovision, though at the cost of increased dysphotopsia and reduced contrast sensitivity.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148264697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Use of intracameral antibiotics prophylaxis in patients with posterior capsular rupture during cataract surgery: systematic review and meta-analysis.","authors":"Sheridan Lam","doi":"10.1097/j.jcrs.0000000000001953","DOIUrl":"10.1097/j.jcrs.0000000000001953","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"629-630"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13200856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitris Kazakos, Jan A Venter, Stephen J Hannan, David Teenan, David R Cooper, Steven C Schallhorn, Colin W Berry, Noelle C Hannan, Dasi Raju, Julie M Schallhorn
{"title":"Primary calcification of hydrophilic acrylic lenses in a large population: incidence and outcomes of lens exchange procedures.","authors":"Dimitris Kazakos, Jan A Venter, Stephen J Hannan, David Teenan, David R Cooper, Steven C Schallhorn, Colin W Berry, Noelle C Hannan, Dasi Raju, Julie M Schallhorn","doi":"10.1097/j.jcrs.0000000000001875","DOIUrl":"10.1097/j.jcrs.0000000000001875","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the incidence of primary opacification and analyze the outcomes of intraocular lens (IOL) exchange procedures.</p><p><strong>Setting: </strong>Private clinics, United Kingdom.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Methods: </strong>Electronic charts of all patients implanted with LENTIS lenses between 2010 and 2015 were reviewed, and the incidence of opacification was calculated. The data of patients who developed opacification were compared with those who did not. In eyes requiring IOL exchange due to opacification, visual and refractive outcomes of the last available postexchange visit were analyzed. The analysis was performed separately for eyes with multifocal and monofocal secondary IOLs.</p><p><strong>Results: </strong>47 171 LENTIS IOLs were implanted of which 2426 (5.1%) opacified. Of the opacified lenses, 1568 (3.3% of the whole cohort) required an IOL exchange. The mean time from primary treatment to opacification diagnosis was 6.9 ± 2.2 years. Patients who developed opacification had a higher prevalence of preoperative myopia. Of all eyes requiring an IOL exchange, the secondary IOL was monofocal in 43.0% and multifocal in 57.0% of eyes. Postexchange corrected visual acuity was 0.00 ± 0.13 logMAR (20/20) in eyes with monofocal secondary IOLs and -0.02 ± 0.08 logMAR (20/20 +1 ) in eyes with multifocal secondary IOLs. The final anatomical position of the secondary IOL was as follows: in-the-bag fixation 67.9%, ciliary sulcus fixation 30.1%, iris-claw fixation 0.6%, and iris suturing or scleral fixation 1.4%.</p><p><strong>Conclusions: </strong>Exchange of opacified IOL was performed safely in most of the patients who developed opacification, including those with prior Nd:YAG capsulotomy, with good visual and refractive outcomes.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"551-560"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13200899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145959621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}