Journal of cataract and refractive surgery最新文献

{"title":"Comparison of intraocular lens power formulas for negative diopter intraocular lens implantation for high myopia.","authors":"Woong-Joo Whang, Kyungmin Koh, Kenneth J Hoffer, Domenico Schiano-Lomoriello, Enrico Lupardi, Leonardo Taroni, Hungwon Tchah, Giacomo Savini","doi":"10.1097/j.jcrs.0000000000001569","DOIUrl":"10.1097/j.jcrs.0000000000001569","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the accuracy of intraocular lens (IOL) power calculation formulas for myopic eyes requiring negative diopter-powered IOLs.</p><p><strong>Design: </strong>Retrospective case series.</p><p><strong>Setting: </strong>Kim's Eye Hospital, College of Medicine, Konyang University, Seoul, South Korea and Yeouido St. Mary Hospital, Seoul, South Korea.</p><p><strong>Methods: </strong>61 eyes that underwent phacoemulsification with implantation of a negative power IOL were investigated. The trueness, precision, and accuracy of IOL power calculation were assessed for the Barrett Universal II (BUII), EVO 2.0, Haigis, Hoffer QST, Holladay 1, and SRK/T formulas using the Eyetemis online tool. The analysis was performed using (1) the ULIB IOL constants and (2) after constant optimization.</p><p><strong>Results: </strong>With ULIB constants, the Haigis, Holladay 1, and SRK/T resulted in a hyperopic mean prediction error (PE) >1.00 diopter (D), which was significantly different from zero (adjusted P < .05). The mean PE of the remaining formulas was closer to zero. The absolute PE was significantly higher with the Holladay 1 and SRK/T (adjusted P < .05) with respect to the remaining formulas. After constant optimization, the outcomes of traditional formulas improved and no statistically significant differences were found among any of the formulas in trueness, precision, and accuracy. The percentage of eyes with an absolute PE within 0.50 D was low (<50%) even after constant optimization.</p><p><strong>Conclusions: </strong>With ULIB constants, the BUII, EVO 2.0, and Hoffer QST were more accurate than traditional formulas in eyes with negative diopter IOLs. The results of IOL power calculation in these eyes remain poor even after constant optimization.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"119-125"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to: Intraocular pressure rises during laser in situ keratomileusis: comparison of 3 femtosecond laser platforms.","authors":"","doi":"10.1097/j.jcrs.0000000000001595","DOIUrl":"10.1097/j.jcrs.0000000000001595","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":"51 2","pages":"178"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of intraocular lens power calculation in patients with endothelial dystrophy without edema.","authors":"Asaf Shemer, Maayan Fradkin, Biana Dubinsky-Pertzov, Olga Reitblat, Francis Simaan, Ruti Sella, Eran Pras, Adi Einan-Lifshitz","doi":"10.1097/j.jcrs.0000000000001578","DOIUrl":"10.1097/j.jcrs.0000000000001578","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the accuracy of several intraocular lens (IOL) formulas for patients with endothelial dystrophy (ED) without edema treated with cataract surgery alone.</p><p><strong>Setting: </strong>1 academic, tertiary referral center.</p><p><strong>Design: </strong>Comparative retrospective cohort study.</p><p><strong>Methods: </strong>The predicted refractive results of patients with ED who underwent cataract surgery were assessed and compared with a matched control group. The accuracy of 5 different IOL formulas, Haigis, Holladay 1, Barrett Universal II (BUII), SRK/T, and Kane, was evaluated and compared between the groups. The SDs of the prediction error (PE) of all formulas were compared.</p><p><strong>Results: </strong>221 eyes were included in this study. 50 (23%) eyes of patients with ED and 171 (77%) control eyes. There was no significant difference between the 2 groups in clinical and demographical characteristics ( P > .05). The postoperative spherical equivalent was -0.37 diopters (D) in the ED group and -0.30 D in the control group ( P = .8). Overall, both groups had a comparable SD of the PE and absolute PE in all formulas ( P > .05). In the ED group, absolute PE was 0.34 D for Haigis, 0.32 D for Holladay 1, 0.32 D for BUII, 0.38 D for SRK/T, and 0.32 D for Kane formulas. No statistically significant difference between formulas was found.</p><p><strong>Conclusions: </strong>The prediction accuracy of IOL power calculation in patients with ED was found comparable both between formulas and in comparison with healthy controls. This suggests that in patients with guttate without edema, the IOL power calculations are as effective and accurate as in healthy eyes.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"141-146"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using a large language model to process biometry reports and select intraocular lens for cataract surgery.","authors":"Jeremy C K Tan","doi":"10.1097/j.jcrs.0000000000001620","DOIUrl":"10.1097/j.jcrs.0000000000001620","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathological Characteristics of Zonular Fibers and Lens Capsule and Their Relationship to Clinical Features in Intraocular Lens Dislocation.","authors":"Akira Hirata, Keiko Mine, Ken Hayashi, Keisuke Ohta","doi":"10.1097/j.jcrs.0000000000001607","DOIUrl":"10.1097/j.jcrs.0000000000001607","url":null,"abstract":"<p><strong>Purpose: </strong>To identify the histopathologic changes in the lens capsule of eyes with in-the-bag intraocular lens (IOL) dislocation.</p><p><strong>Design: </strong>Pathological analysis and correlation with clinical findings.</p><p><strong>Setting: </strong>Hayashi Eye Hospital (Fukuoka, Japan).</p><p><strong>Methods: </strong>Specimens of twenty-five IOL-lens capsule complexes obtained during surgery were processed for scanning electron microscopy (SEM). Backscattered electron images of cross-sections of the lens capsule were obtained using SEM. Ultrastructural changes in the lens capsule were examined and analyzed based on preoperative clinical findings.</p><p><strong>Results: </strong>The mean age was 70.0±18.0 years. The mean time from initial cataract surgery to IOL removal was 12.5±7.0 years. Of these, nine eyes had exfoliation syndrome (XFS), seven had high myopia, five underwent vitrectomy, and three had atopic dermatitis. The mean age of the XFS cases was 86.6±4.3 years. All XFS specimens demonstrated highly associated ruptured zonular fibers (p <.01). In the 16 non-XFS cases, the mean age was 61.2±17.5 years, significantly younger than in the XFS cases (p <.01); 14 of the 16 specimens had a detachment of zonular lamella (ZL), which was highly associated (p <.01). Four non-XFS eyes exhibited clear capsules, demonstrating significant associations with capsular delamination (p < .01) and the absence of lens epithelial cells (p < .01), resembling dead-bag syndrome.</p><p><strong>Conclusions: </strong>Structural changes in the lens capsule associated with IOL dislocation are mainly of three types: ruptured zonular fibers in XFS, detachment of the ZL, and capsular delamination. They vary according to the associated diseases, suggesting that prevention and treatment should consider the underlying pathophysiology.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractive accuracy of the new Barrett formula using segmented axial length compared with that of the traditional Barrett Universal II formula.","authors":"Seiichiro Hata, Manabu Kobayashi","doi":"10.1097/j.jcrs.0000000000001609","DOIUrl":"10.1097/j.jcrs.0000000000001609","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the refractive accuracy of the Barrett True axial length (BTAL) formula, newly integrated into ARGOS, with that of the Barrett Universal II (BUII) formula calculated using axial length (AL) from IOL Master 700.</p><p><strong>Setting: </strong>Private clinics in Kanagawa, Japan.</p><p><strong>Design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>We assessed eyes of patients who underwent cataract surgery with SY60WF IOL implantation, using ARGOS and IOL Master 700. The predicted refraction for BTAL was back-calculated. Refractive prediction errors (RPEs) for BTAL, BUII with ARGOS (segmented BUII), and BUII with IOL Master 700 (composite BUII) were compared. We primarily aimed to demonstrate the non-inferiority of BTAL to composite BUII in absolute RPE.</p><p><strong>Results: </strong>We included 209 eyes from 209 patients. BTAL met the non-inferiority criteria, as the upper confidence interval (CI) boundary was below the non-inferiority margin of 0.10 diopters (D) for the difference in absolute RPE (-0.03 D; 95% CI: -0.06 to 0.01). In short eyes (AL ≤ 22.5 mm), the median absolute RPEs for BTAL, segmented BUII, and composite BUII were 0.25, 0.18, and 0.37 D, respectively, with significant differences between BTAL and composite BUII (p = 0.028) and segmented BUII and composite BUII (p = 0.018). In long eyes (AL > 26 mm), the median absolute RPEs were 0.21, 0.20, and 0.28 D for BTAL, segmented BUII, and composite BUII, respectively.</p><p><strong>Conclusions: </strong>BTAL was non-inferior to composite BUII in absolute RPE. BTAL is an accurate and useful intraocular lens power calculation formula, even in eyes with short and long AL.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143033139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depth of focus as a function of spherical aberration using adaptive optics in pseudophakic subjects.","authors":"Juan Tabernero, Carles Otero, John Kidd, Laura Zahiño, Ana Noia, Jose Luis Güell, Pablo Artal, Shahina Pardhan","doi":"10.1097/j.jcrs.0000000000001608","DOIUrl":"10.1097/j.jcrs.0000000000001608","url":null,"abstract":"<p><strong>Purpose: </strong>To measure visual acuity at three different defocus planes in pseudophakic subjects with varying levels of spherical aberration induced by an adaptive optics visual simulator. The study aimed to simulate Extended Depth of Focus (EDOF) intraocular lenses (IOLs).</p><p><strong>Setting: </strong>Private hospital (IMO, Barcelona, Spain).</p><p><strong>Design: </strong>Observational case series; modelling theory.</p><p><strong>Methods: </strong>Through-focus visual acuity was measured in 26 pseudophakic subjects (age 63 ± 10 years old) with an adaptive optics visual simulator optimized for clinical use (VAO, Voptica SL, Murcia, Spain). Measurements were made under five different conditions of induced negative spherical aberration: 0, -0.07, -0.15, -0.23 and -0.30 μm (pupil diameter: 4.5 mm). Results were also modelled using ray tracing simulations.</p><p><strong>Results: </strong>On average, depth of focus was extended when spherical aberration increased from -0.07 to -0.15 μm (4.5 mm pupil diameter). Some indivisuals (27%) experienced improved depth of focus with higher magnitudes of spherical aberration, while others (23%) exhibited no benefit from increased (negative) SA, as visual acuity dropped below acceptable levels. Depth of focus calculations based on ray tracing showed general agreement with the measurements.</p><p><strong>Conclusions: </strong>The visual conditions of EDOF IOLs were artificially recreated in a population of pseudophakic patients implanted with a monofocal IOL. The variability seen across subjects in visual acuity at different defocus planes suggests that visual simulators might be capable of screening subjects for suitability and tolerability of these advanced technology lenses.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Intraocular Lens Power Calculation Based on Distance from Haptic to Principal Object Plane.","authors":"Youngsub Eom, Seul Ki Yang, Minji Woo, Jae-Ik Kim, Kwang Eon Choi, Dong Hyun Kim, Hwa Lee, Young-Woo Suh, Jong Suk Song, David L Cooke","doi":"10.1097/j.jcrs.0000000000001611","DOIUrl":"10.1097/j.jcrs.0000000000001611","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the impact of the distance from the most-anterior surface of the optic to the principal object plane (POP) and from the foremost haptic to the principal object plane (H-POP) on the intraocular lens (IOL) power calculation.</p><p><strong>Setting: </strong>A tertiary hospital.</p><p><strong>Design: </strong>Optical simulation and retrospective cross-sectional study.</p><p><strong>Methods: </strong>The optical simulation study plotted changes in the POP and H-POP as a function of IOL power using ICB00 IOL configuration data. The clinical study included 102 eyes of 102 patients implanted with ICB00 IOL to examine the correlation between changes in both the POP and the H-POP, and the prediction error calculated using the Barrett Universal II formula with varying IOL power.</p><p><strong>Results: </strong>The ICB00 IOL showed minor fluctuations in the POP (0.21 mm to 0.30 mm) with changing IOL power. The H-POP increased stepwise from 5.0 D, peaking at 0.60 mm at 16.0 D, then decreased to a minimum of 0.14 mm at 34.0 D. The prediction error graph primarily mirrored the pattern of changes in the H-POP rather than the POP with varying IOL power. Linear regression showed a significant myopic shift in prediction error as IOL power increased beyond 16.0 D (Y = -0.069X+1.420, R2=0.178, p<0.001).</p><p><strong>Conclusion: </strong>For the ICB00 IOL, the H-POP has more impact on IOL power calculation than the POP itself. For more accurate IOL power calculations, it is essential for all IOL manufacturers to provide comprehensive information on both optic and haptic geometries, which will enable the precise calculation of H-POP.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxic Anterior Segment Syndrome: A 2012-2022 Update on the Most Common Causes.","authors":"Melissa Yao, Shwetha Mudalegundi, Kevin Eid, Nour Bundogji, Neil Kelkar, Liliana Werner, Nick Mamalis","doi":"10.1097/j.jcrs.0000000000001610","DOIUrl":"10.1097/j.jcrs.0000000000001610","url":null,"abstract":"<p><strong>Purpose: </strong>To identify trends in the reporting of toxic anterior segment syndrome (TASS) to the American Society of Cataract and Refractive Surgery (ASCRS) TASS Force from 2012-2022.</p><p><strong>Setting: </strong>John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.</p><p><strong>Design: </strong>Cross-sectional study.</p><p><strong>Methods: </strong>TASS questionnaires on instrument cleaning and sterilization, and extraocular and intraocular products used during cataract surgery were available on the American Society of Cataract and Refractive Surgery website. A retrospective analysis of questionnaires submitted by surgical centers reporting cases of TASS was performed between January 1, 2012, and December 31, 2022, to identify commonly held practices that could cause TASS.</p><p><strong>Results: </strong>Data from 77 questionnaires were analyzed. The reporting centers performed 56,319 cataract surgeries and reported 539 cases of TASS from January 1, 2012, to December 31, 2022. Common practices associated with the TASS outbreaks in the surveys included re-use of single-use cannulas, phacoemulsification, and irrigation/aspiration tips (69%), use of enzymatic cleaners (40%), inadequate flushing of phacoemulsification and irrigation/aspiration handpieces (27%), reuse of phacoemulsification tubing (22%), use of preservative-containing intracameral anesthetic (18%), and addition of antibiotics to balanced salt solution (17%).</p><p><strong>Conclusions: </strong>The surveys identified commonly held practices associated with TASS while showcasing trends over the past 10 years. Understanding these findings and the safe alternatives will allow surgical center personnel to change their practices as needed to prevent this complication.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital vs manual axis marking for toric phakic intraocular lens alignment: prospective randomized intraindividual trial.","authors":"Wolfgang List, Martin Dirisamer, Wolfgang Johann Mayer, Mehdi Shajari, Wilfried Glatz, Jakob Gran, Andreas Wedrich, Gernot Steinwender","doi":"10.1097/j.jcrs.0000000000001553","DOIUrl":"10.1097/j.jcrs.0000000000001553","url":null,"abstract":"<p><strong>Purpose: </strong>To compare visual and refractive outcomes and postoperative axis alignment for toric implantable collamer lens (ICL) implantation in astigmatic myopia using manual vs digital marking techniques.</p><p><strong>Setting: </strong>Department of Ophthalmology, Medical University of Graz, Graz, Austria.</p><p><strong>Design: </strong>Prospective randomized single-centered intraindividual comparison.</p><p><strong>Methods: </strong>Patients undergoing bilateral toric ICL implantation for myopia with astigmatism ≥0.5 diopters (D) were enrolled. Patients received both marking techniques, and randomization was performed. Postoperative retroillumination photography assessed axis alignment, and visual and refractive parameters were evaluated. Duration of the surgeries was recorded.</p><p><strong>Results: </strong>The study included 20 patients and 40 eyes. Preoperative visual and refractive parameters showed no significant differences. Postoperatively, residual astigmatism ( P = .824) and spherical equivalent ( P = .309) were comparable. No notable differences between right and left eyes in preoperative ( P = .371) and postoperative ( P = .824) astigmatism were observed. Although slight, corrected distance visual acuity (CDVA) increased in both groups postoperatively ( P = .381). Gain in CDVA was comparable between marking techniques ( P = .637). Safety and efficacy indices were comparable ( P = .991 and P = .189, respectively). Postoperative axial misalignment was 2.8 ± 3.1 degrees in the digital- and 4.4 ± 5.1 degrees in the manual group ( P = .260). Vector analysis showed no significant differences between manual and digital marking. Duration remained uninfluenced by the marking technique ( P = .970) and side of surgery ( P = .682).</p><p><strong>Conclusions: </strong>Digital and manual marking techniques provided comparable results in axis alignment, surgical duration, and visual and refractive outcomes. Both methods were viable for precise axis alignment, with digital marking offering a potential advantage in efficacy.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"23-30"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142347304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}