Journal of cataract and refractive surgery最新文献

{"title":"Intraocular lens power calculation accuracy after keratorefractive lenticule extraction with the novel ESCRS post keratorefractive surgery calculator.","authors":"Lischke Roman, Wiltfang Rainer, Bechmann Martin, Kreutzer Thomas, Priglinger Siegfried G, Dirisamer Martin, Luft Nikolaus","doi":"10.1097/j.jcrs.0000000000001673","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001673","url":null,"abstract":"<p><strong>Purpose: </strong>To compare IOL power calculation accuracy after keratorefractive lenticule extraction (KLEx) using the ESCRS online calculator versus ray tracing, the current gold standard.</p><p><strong>Setting: </strong>Multicenter study at Ludwig-Maximilians-University Eye Hospital (Munich, Germany) and SMILE Eyes Clinics (Germany, Austria).</p><p><strong>Design: </strong>Multicenter, cross-sectional study.</p><p><strong>Methods: </strong>Patients who underwent SMILE (KLEx) and subsequent cataract surgery were included. Post-hoc IOL power calculations were performed using ray tracing (Okulix) and the ESCRS calculator (Barrett True-K post-LVC, Hoffer-QST post-LVC, EVO post-LVC). Accuracy, trueness, and precision were compared descriptively.</p><p><strong>Results: </strong>Seven eyes from seven patients were analyzed. EVO post-LVC showed the lowest mean error (-0.24±0.50D), followed by ray tracing (-0.28±0.32D) and Hoffer-QST post-LVC (-0.36±0.59D). Ray tracing, EVO post-LVC and Barrett True-K post-LVC achieved 100% accuracy within ±1.00D. Ray tracing had the lowest mean absolute error (0.35D).</p><p><strong>Conclusions: </strong>Ray tracing and ESCRS post-LVC formulas improve IOL power calculations, emphasizing the need for tailored approaches in post-KLEx eyes.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conversion of disclosed lens power formula constants.","authors":"Achim Langenbucher, Peter Hoffmann, Alan Cayless, Jascha Wendelstein, Nóra Szentmáry","doi":"10.1097/j.jcrs.0000000000001676","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001676","url":null,"abstract":"<p><strong>Purpose: </strong>To present a concept for inter-converting constants of disclosed lens power formulae and to simplify these conversions to linear prediction models for clinical use.</p><p><strong>Setting: </strong>Augen- und Laserklinik Castrop-Rauxel, Germany.</p><p><strong>Design: </strong>Retrospective single centre case series.</p><p><strong>Methods: </strong>Analysis based on a dataset with biometric measurements of 19,472 eyes in a cataractous population performed with the IOLMaster 700. The formula constant conversion from formula A to B includes 2 steps: calculation of the lens power using formula A with variation of formula A constant, and back calculation of the constant for formula B for all constant values of formula A using nonlinear iterative optimization techniques to minimize the sum of squared formula B prediction error.</p><p><strong>Results: </strong>Formula conversion was calculated for the SRK/T A constant (A = 117 to 121), Hoffer Q (pACD = 4.2 to 6.8), Holladay 1 (SF 0.5 to 3.0), Haigis (a0 0.0 to 2.5 with a1/a2 = 0.4/0.1) and Castrop (C 0.15 to 0.50 with H/R = 0.0) formulae. As the conversions follow linear dependencies, linear regression models were fitted to simplify formula constant conversions in clinical routine.</p><p><strong>Conclusion: </strong>Conversions of formula constants could be used in cases where, for example, new lens models are launched with only the nominal SRK/T A constant available, or in situations where constants for some of the formulae are not available. Conversions to constant triplets for the Haigis or Castrop formula require additional nonlinear boundary conditions to take full advantage of formulae with multiple constants.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric assessment of the Chinese version of the Near Activity Visual Questionnaire in presbyopia using Rasch analysis.","authors":"Yuecheng Ren, Jiawei Li, Xinyu Jiang, Jyoti Khadka, Yiran Wang, Chenfeng Gu, Yue Wu, Qinmei Wang, Jinhai Huang, Rongrong Gao","doi":"10.1097/j.jcrs.0000000000001675","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001675","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the psychometric properties of the Chinese version of the Near Activity Visual Questionnaire (NAVQ).</p><p><strong>Setting: </strong>XXX.</p><p><strong>Design: </strong>Randomization single-center observational study.</p><p><strong>Methods: </strong>The original English version of the NAVQ was translated and cross-culturally adapted into Mandarin. Participants with presbyopia completed the NAVQ. Clinical data, including monocular and binocular habitual near visual acuity (HNVA), manifest refraction spherical power, cylindrical power and near addition (ADD) were collected. The NAVQ was psychometrically assessed using Rasch analysis metrics. The criterion validity was evaluated by correlating the Rasch score with clinical data.</p><p><strong>Results: </strong>One hundred and seventy-five participants with presbyopia (median age: 65 years old, female: 42.9%) were included. Rasch analysis demonstrated that the NAVQ was unidimensional, with ordered thresholds, good measurement precision (person separation measure: 2.86), and acceptable targeting (0.99 logit). The NAVQ Rasch score correlated strongly with binocular HNVA ( rs = 0.678) compared to better-eye and worse-eye VA. It also showed moderate correlations with additional power ( rs = 0.523), and the spherical equivalent for presbyopia correction in the better-eye ( rs = 0.656) and worse-eye ( rs = 0.647) (all P < 0.001).</p><p><strong>Conclusion: </strong>The Chinese version of the NAVQ demonstrated good psychometric properties and validity in a Chinese presbyopia population.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective, Randomized, Controlled Multicenter Study of a Monofocal Extended Depth of Focus IOL Compared to a Standard Aspheric Monofocal IOL.","authors":"Mark Packer, Tiago Monteiro, Cedric Schweitzer, Paul Rosen","doi":"10.1097/j.jcrs.0000000000001672","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001672","url":null,"abstract":"<p><strong>Purpose: </strong>Investigate safety and effectiveness of a monofocal enhanced depth of focus intraocular lens (mono-EDoF IOL, xactTM Mono-EDoFTM Model ME4) compared to an aspheric monofocal IOL (TECNIS 1-Piece IOL Model ZCB00).</p><p><strong>Setting: </strong>Sites in United Kingdom, France, and Portugal.</p><p><strong>Design: </strong>Prospective, multicenter, controlled, single-masked, randomized 2:1 (test:control) clinical trial.</p><p><strong>Methods: </strong>Adults ≥40 years of age with bilateral cataracts, expected post-operative refractive astigmatism of ≤1.0D and calculated lens power 18D to 30D underwent implantation of either mono-EDoF or aspheric monofocal IOL in both eyes. Primary endpoints assessed at day 120-180 included monocular uncorrected distance visual acuity (UDVA) and visual disturbances. Secondary endpoints were monocular uncorrected intermediate visual acuity (UIVA) and monocular distance corrected intermediate visual acuity (DCIVA).</p><p><strong>Results: </strong>Sixty-five patients were randomized; 45 patients (95.2%) with Mono-EDoF and 20 patients (95.2%) with control completed the study. Compared with control, Mono-EDoF had significantly better monocular UDVA (P=0.0128), monocular UIVA (P<0.001), and monocular DCIVA (P<0.001). Monocular and binocular defocus curve measurements confirmed increased depth-of-focus for the Mono-EDoF compared to the control IOL by approximately 0.50D and 0.75D respectively. Contrast sensitivity measured under mesopic conditions with and without glare was similar between groups. Halo or glare was reported by 25.7% and 33.3% of patients in the Mono-EDoF group, respectively, and 22.2% and 25.0%, respectively, in the control group.</p><p><strong>Conclusions: </strong>The xact Mono-EDoF ME4 IOL is a safe and effective alternative to a monofocal IOL. It provides superior intermediate VA compared with an aspheric monofocal IOL without compromising contrast sensitivity or creating unwanted photic phenomena.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Videographic and Microbiologic Evaluation of Eye Drop Bottle Contamination in Clinics: A Pilot Study.","authors":"Ishani P Majmudar, Harsha R Kaul, Anushree Aneja, Jasmyne E McCoy, Sahana Aggarwal, Nathan P Gill, Justin Mussman, Robert O Baker, David J Palmer, Manjot K Gill","doi":"10.1097/j.jcrs.0000000000001670","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001670","url":null,"abstract":"<p><strong>Background: </strong>Many multidose eyedrops in the clinic and operating room are discarded after single use due to cross-contamination concerns. This practice contributes to significant hospital costs, drug shortages, and unnecessary greenhouse gas emissions.</p><p><strong>Methods: </strong>9-week, prospective, observational study of 97 patients.</p><p><strong>Objective: </strong>To validate the safety of multidose eyedrops in the ophthalmology clinic by ASORN-trained technicians using a videographic and microbiological analysis. Secondly, to determine optimal culturing conditions to prevent environmental contamination.</p><p><strong>Results: </strong>During eyedrop administration, no videos demonstrated bottle-to-patient contact. 12/96 (12.5%) plates demonstrated growth, likely due to environmental contamination. Mass spectrometry revealed non-pathogenic and common species for 8 identifiable growths. Environmental contamination is minimized by use of a biosafety cabinet.</p><p><strong>Conclusion: </strong>We found no clinical correlation between the use of multidose eyedrop bottles and infection on multiple patients in the ophthalmology clinic. We recommend using a biosafety cabinet to establish a national consensus for multidosing eyedrops and to improve inter-study comparisons.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Practice Patterns for Cataract Surgery - A Cross-Sectional European Study.","authors":"Denise Yang-Seeger, Yan Ning Neo, Oliver Findl, Akanksha Bagchi, Sjoerd Elferink, Johannes Birtel","doi":"10.1097/j.jcrs.0000000000001669","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001669","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate pre- and postoperative visits following cataract surgery in Europe and to assess the environmental impact of patient travel.</p><p><strong>Setting: </strong>High-volume cataract centers in 16 European countries.</p><p><strong>Design: </strong>A cross-sectional survey was developed and distributed by the Young Ophthalmologists for Sustainability (YOFS), a working group of the European Society of Cataract and Refractive Surgeons (ESCRS).</p><p><strong>Methods: </strong>Outcome measures included pre- and postoperative clinic visits, time and location of follow-ups, proportion of delayed and immediate sequential bilateral cataract surgery (DSBCS and ISBCS), and the option of remote follow-up visits.</p><p><strong>Results: </strong>In total, 89 responses were collected. Most departments performed 2,000 to 5,000 cataract surgeries per year. If ISBCS was offered, this accounted for less than 5% in most units. The number of preoperative visits varied between 1 (78%) and ≥3 (4%), with half of the units undertaking preoperative visits before the second eye surgery. The number of postoperative visits ranged from 1 to 4; most centers performed 1 (35%) or 2 (45%). In total, the mean number patient reviews was 5.7 (range: 3.3-9.3) for DSBCS and 3.0 (range: 2.3-4.0) for ISBCS. Remote follow-up visits were only offered by 6 centers.</p><p><strong>Conclusions: </strong>Large regional differences regarding the frequency of pre- and postoperative visits for cataract surgery were observed. Reducing the number of face-to-face visits may reduce costs for healthcare systems and patients, improve patient convenience, improve capacity, and may serve as a step towards more sustainable care by reducing travel-related carbon emissions.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical confirmation by a thick-lens formula of the optimized A-constant (as calculated by a thin-lens formula) of a new intraocular lens.","authors":"Giacomo Savini, Daniela Nicolosi, Kenneth J Hoffer, Catarina P Coutinho, Maria Cristina Curatolo, Domenico Schiano-Lomoriello","doi":"10.1097/j.jcrs.0000000000001671","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001671","url":null,"abstract":"<p><strong>Purpose: </strong>To provide a physical explanation for the A-constant of a new enhanced monofocal intraocular lens (IOL) by evaluating the relationship between the postoperative anterior chamber depth constant (ACD-constant) predicted by the Olsen formula, the ACD predicted by the Holladay formula and the postoperative ACD measured by anterior segment optical coherence tomography (AS-OCT).</p><p><strong>Setting: </strong>IRCCS Bietti Foundation, Rome, Italy.</p><p><strong>Design: </strong>Retrospective case series.</p><p><strong>Methods: </strong>In a series of consecutive patients that underwent cataract surgery with the same enhanced monofocal IOL, the A-constant of the SRK/T formula was optimized. The postoperative distance between the corneal epithelium and the anterior surface of the IOL was measured by AS-OCT (MS-39, CSO) and compared to the ACD predicted by the Olsen formula (PhacoOptics) and the method described by Holladay to correlate the thin-lens IOL position to the thick-lens IOL position.</p><p><strong>Results: </strong>Twenty-one eyes were investigated. The back-calculated optimized A-constant was 118.33. The mean measured IOL distance from the corneal epithelium was 4.24 ± 0.28 mm. Based on the A-constant value of 118.33, PhacoOptics calculated that the mean predicted ACD constant specific for this IOL was 4.28 mm, while the mean predicted ACD based on the individual preoperative biometric parameters was 4.17 ± 0.23 mm. According to the Holladay method, the IOL distance from the corneal vertex was 4.21 ± 0.36 mm. Repeated measures ANOVA disclosed that the difference among the 3 values was not significant (p = 0.3535).</p><p><strong>Conclusions: </strong>The optimized A-constant correlates well with the thick-lens values calculated for the postoperative ACD.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Corneal Endothelium Damage with a New Handheld Fragmentation Device.","authors":"Liliana Werner, Neil Kelkar, Kevin Eid, Reiker G Ricks, Emilie L Ungricht, Jeff H Pettey","doi":"10.1097/j.jcrs.0000000000001668","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001668","url":null,"abstract":"<p><strong>Purpose: </strong>To quantify damage to corneal endothelial cells (CECs) from a new handheld lens fragmentation device and compare it with damage from a standard phacoemulsification device.</p><p><strong>Setting: </strong>John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</p><p><strong>Design: </strong>Experimental Study.</p><p><strong>Methods: </strong>Fifteen New Zealand white rabbits received bilateral surgery. Their eyes were divided into 3 groups (10 eyes/group): Intrepid Balanced Tip (Centurion Ozil handpiece; Alcon), miCOR 700 (Zeiss) half throttle (infusion/aspiration only), or full throttle (lens agitator engaged). After incision, the tip of each device was inserted into the anterior chamber and activated for 30 seconds. Following euthanasia and enucleation, the corneas were removed, stained with trypan blue/alizarin red, and photographed in a standardized manner (five X400 magnification photos from the center of each cornea). The ImageJ program was used to evaluate CEC damage and loss in the photographs.</p><p><strong>Results: </strong>The overall differences among the 3 groups regarding intact, damaged, and lost cells were statistically significant. However, by applying the Bonferroni correction, only the post-hoc pairwise comparisons between groups 1 (phaco tip) and 2 (miCOR tip, half throttle, without lens agitator engaged) were statistically significant regarding the 3 above-mentioned parameters.Conclusion: miCOR is a handheld, finger-controlled lens removal device with a blunt and rounded tip that vibrates at a low frequency, using mechanical agitation for nuclear disassembly. This acute rabbit study suggests CEC damage from the device, when the lens agitator is engaged is comparable to that of standard torsional phacoemulsification.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of two side-port incisions in phacoemulsification.","authors":"Huafang Guo, TingTing Peng, Wnjing Luo, Anqi Xie","doi":"10.1097/j.jcrs.0000000000001661","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001661","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this project is to compare the accuracy, safety, and consistency of near-square and asymmetric trapezoid side-port incisions in cataract surgery.</p><p><strong>Setting: </strong>Aier Eye Hospital of Wuhan University, Wuhan Hubei Province, China.</p><p><strong>Design: </strong>Prospective pilot study.</p><p><strong>Methods: </strong>The patients were divided into Groups A and B using the random number table method. Group A received a near-square side-port incision (SPI) with a 22G needle, and Group B received an asymmetric trapezoid SPI with a 15-degree blade. We contrasted the differences in incision length, width, and shape; surgical time; and postoperative intraocular pressure (IOP) between the two groups.</p><p><strong>Results: </strong>Eighty eyes from 80 patients were included. The mean external width of incision in Group A was much smaller than that in Group B (p < .01), while the internal width in Group A was significantly larger (p < .01). In Group A, there is no statistically significant difference between the external and internal incision diameters (p = .081). In Group B, the external diameter is obviously larger than the internal diameter (p < .01). The incision diameter consistency in Group A was higher than that in Group B. There was no statistically significant difference in incision length between the two groups (p = 0.67). One day after surgery, there were no significant differences in incision morphology (p = 1.0; .723) or operating time between the two groups (p = .89). There was no obvious incision leakage in either group after surgery (p =.337).</p><p><strong>Conclusions: </strong>The present study suggests that a near-square side-port with a 22G needle is smaller and results in better incision consistency. Moreover, the 22G needle is inexpensive and can be easily obtained.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Spore-Like Calcification on a Hydrophilic Acrylic Intraocular Lens.","authors":"Sheng-Chu Chi, Shih-Jen Chen","doi":"10.1097/j.jcrs.0000000000001662","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001662","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}