Journal of cataract and refractive surgery最新文献

{"title":"Visual and subject-reported outcomes of a wavefront shaping extended depth of focus intraocular lens implanted bilaterally with monovision.","authors":"Miguel A Teus, Thomas Kohnen, James Ball, Isabelle E Y Saelens, Gerard Sutton, Michael Lawless, Caridad Perez Vives, Ruth Lapid-Gortzak","doi":"10.1097/j.jcrs.0000000000001636","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001636","url":null,"abstract":"<p><strong>Purpose: </strong>To report visual and subject-reported outcomes after bilateral implantation of non-diffractive extended-depth-of-focus (EDoF) intraocular lens (IOL) (AcrySof IQ Vivity) with monovision correction during cataract or refractive lens exchange (RLE) surgery.</p><p><strong>Setting: </strong>Europe, Australia, and New Zealand.</p><p><strong>Design: </strong>Subgroup analysis of Vivity registry.</p><p><strong>Methods: </strong>Binocular uncorrected and corrected visual acuities at distance (UCDVA/CDVA), intermediate (UCIVA/DCIVA), and near (UCNVA/DCNVA) were assessed at 3-6 months after implantation. Subject-reported outcomes (satisfaction, spectacle independence, visual disturbances) were evaluated. Data were reported by surgery type and monovision level at low (>-0.75D and ≤-0.50D), medium (>-1.00D and ≤-0.75D), and high (≤-1.00D).</p><p><strong>Results: </strong>Overall, 200 (of 885) subjects met the monovision criteria (cataract, n=170; RLE, n=24). Excellent binocular UCDVA and UCIVA and excellent/good UCNVA (mean±SD logMAR) were noted for cataract (0.031±0.102; 0.081±0.114; 0.217±0.144) and RLE (0.006±0.093; -0.003±0.089; 0.123±0.097) groups, respectively. Most subjects were spectacle-independent for distance and intermediate vision and very/fairly satisfied with sight; >87% from each surgery group reported no visual disturbances. Excellent UCDVA was preserved at low and medium monovision. Better UCNVA was observed for medium and high vs. low monovision levels, whereas spectacle independence for distance and intermediate was higher for medium vs. low/high monovision. High subject satisfaction and minimal visual disturbances were reported regardless of monovision level.</p><p><strong>Conclusions: </strong>Monovision correction with the non-diffractive EDoF IOL demonstrated excellent-to-good VA at all distances, high levels of spectacle independence and subject satisfaction, and minimal visual disturbances after cataract and RLE surgeries. Overall, medium monovision level performed most favorably, achieving good near VA while preserving excellent distance and intermediate vision.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Postoperative Walking vs. Lying Down on IOL Rotation After Lens Surgery: A Prospective Comparative Study.","authors":"Tyll Jandewerth, Klemens Paul Kaiser, Eva Hemkeppler, Christoph Lwowski, Thomas Kohnen","doi":"10.1097/j.jcrs.0000000000001632","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001632","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the intraocular lens (IOL) rotational stability depending on patient position in the first postoperative hour after femtosecond laser assisted cataract or refractive surgery with implantation of a non-toric IOL in the capsular bag.</p><p><strong>Setting: </strong>Department of Ophthalmology, Goethe-University, Frankfurt, Germany.</p><p><strong>Design: </strong>Prospective, randomized clinical trial.</p><p><strong>Methods: </strong>In this study, 38 eyes of 36 patients received femtosecond laser assisted phacoemulsification and implantation of a non-toric IOL in the capsular bag. Patients were randomized into two groups: patients laid down for one hour after surgery due to the clinical standard (LD group), patients walked around in the first postoperative hour (W group). No miotic eye drops were applied at the end of operation. A retroilluminated slit lamp picture was taken at the end of the operation (baseline), one hour and one day postoperative. Changes in IOL position were measured by an axis between two episcleral landmarks and the haptics of the IOL. Measurements were performed by an image processing application specified for medical and scientific purpose. If not normally distributed, the paired t-test was used. Otherwise, the Mann-Whitney-U-Test was used if data was not normally distributed.</p><p><strong>Results: </strong>IOL rotation in the first hour was 1.80° ± 1.80° in the LD group and 1.21° ± 2.11° in the W group (p=0.123). One day after operation, IOL position differed from the baseline measurement with 1.52° ± 1.89° in the LD group and 1.51° ± 1.69° in the W group (p=0.773).</p><p><strong>Conclusion: </strong>Early postoperative patient position does not seem to influence IOL rotational stability.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraocular lens rotational stability after cataract surgery with and without primary posterior continuous curvilinear capsulorhexis.","authors":"Yulong Huang, Mengting Yu, Xiaobao Liu, Yajing Cai, Chishan Kang, Wenjie Wu","doi":"10.1097/j.jcrs.0000000000001579","DOIUrl":"10.1097/j.jcrs.0000000000001579","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate intraocular lens (IOL) rotational stability and capsular fusion process after cataract surgery with and without primary posterior continuous curvilinear capsulorhexis (PPCCC).</p><p><strong>Setting: </strong>Fujian Provincial Hospital, Fujian, China.</p><p><strong>Design: </strong>Prospective, intraindividual, randomized clinical trial.</p><p><strong>Methods: </strong>This study included 56 adult patients (112 eyes) with bilateral cataract undergoing phacoemulsification cataract surgery with PPCCC in 1 eye (PPCCC group) and conventional cataract surgery in the contralateral eye (NPCCC group). IOL axis orientation and fusion footprint length were measured at 1 day, 1 week, 1 month, 3 months, and 1 year postoperatively using OPD-Scan III, while the capsular bend index (CBI) was assessed at the same timepoints using Pentacam AXL.</p><p><strong>Results: </strong>No between-group difference was found in the absolute rotation from 1 day to 1 year (2.93 ± 1.72 vs 2.66 ± 1.61 degrees, P = .54). The absolute rotation from 1 week to 1 month in the NPCCC group was higher than that in the PPCCC group (1.65 ± 0.68 vs 1.27 ± 0.32 degrees, P = .01). At 1 month postoperatively, both fusion footprint length (9.11 ± 2.74 vs 10.67 ± 2.06 mm, P = .02) and CBI (2.92 ± 0.60 vs 3.25 ± 0.59, P = .03) were lower in the NPCCC group.</p><p><strong>Conclusions: </strong>Cataract surgery involving PPCCC demonstrated comparable outcomes with conventional procedures regarding long-term IOL rotational stability and therefore is a promising option for adult patients with cataract scheduled for toric IOL implantation. PPCCC slightly reduces IOL rotation in the early postoperative period, which can be attributed to accelerated capsular fusion.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"147-155"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual follow-up after cataract surgery: systematic review.","authors":"Angelica Hanna, Diana Lucia Martinez, Marko Popovic, Iqbal Ike K Ahmed, Joshua Teichman","doi":"10.1097/j.jcrs.0000000000001571","DOIUrl":"10.1097/j.jcrs.0000000000001571","url":null,"abstract":"<p><strong>Topic: </strong>To examine the association between virtual postoperative follow-up care and patient outcomes after cataract surgery.</p><p><strong>Clinical relevance: </strong>Cataract surgery is a safe and commonly performed surgery. Follow-up visits are used to monitor for complications. It is uncertain whether virtual follow-up provides a safe alternative to in-person review.</p><p><strong>Methods: </strong>MEDLINE, Embase, and CINAHL were searched from inception to October 2023 for relevant articles containing original data. Studies that (1) included patients who were seen in a virtual follow-up (ie, telephone or video call) for postoperative appointments after cataract surgery and (2) reported patient outcomes were included. Risk of bias (RoB) was assessed using the Newcastle-Ottawa and RoB2 assessment tools. Descriptive statistics were used to summarize findings. The review was registered in PROSPERO (registration number, CRD42023477207), and PRISMA guidelines were followed.</p><p><strong>Results: </strong>The search yielded 1710 records with 7 studies included in this review. The 7 studies reported on 2113 cataract surgeries in 1994 patients. The studies ranged between 2004 and 2020. Most of the studies (5/7) included only patients with uneventful cataract surgery. Virtual follow-ups were all conducted by telephone. The follow-up calls were made at varying timepoints including postoperative day 1 (n = 3), day 7 (n = 2), and day 14 (n = 1). 2 observational studies directly compared patients who had a telephone follow-up with a control group who had an in-person follow-up. There were no significant differences in complication rates ( P = .22) or visual acuity ( P = .28) between these follow-up groups. None of the studies reported serious adverse outcomes from replacing in-person follow-up with telephone follow-up. One study used virtual follow-up in conjunction with in-person visits for elderly patients and found that additional telephone follow-up was associated with decreased surgical recovery time and decreased patient anxiety. 3 studies reported on patient perceptions about telephone follow-up. A common theme was that patients preferred telephone reviews and found them to be more convenient than in-person follow-up.</p><p><strong>Conclusions: </strong>For patients with uneventful cataract surgery, virtual follow-ups seem to be a safe alternative to in-person visits and were preferred by patients. These conclusions are preliminary given the limited literature base, and further study is needed.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"167-174"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endophthalmitis rates after secondary intraocular lens surgeries: 11-year Medicare fee-for-service analysis.","authors":"Caroline H Kerrison, David F Chang, Chen Dun, Jasdeep Sabharwal, Fasika A Woreta","doi":"10.1097/j.jcrs.0000000000001563","DOIUrl":"10.1097/j.jcrs.0000000000001563","url":null,"abstract":"<p><strong>Purpose: </strong>To assess postoperative endophthalmitis (POE) rates and risk factors after secondary intraocular lens (IOL) implantation for preoperative aphakia and IOL exchange combined with or without vitrectomy.</p><p><strong>Setting: </strong>Medicare fee-for-service (FFS) beneficiaries, United States.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Methods: </strong>Medicare FFS beneficiaries who underwent IOL exchange or secondary IOL implantation for preoperative aphakia between January 1, 2011, and November 19, 2022, were identified. POE rates were calculated overall and separately for each surgical category-secondary IOL for aphakia vs IOL exchange, with subsets for concurrent anterior or posterior vitrectomy. Multivariate analysis of potential risk factors was implemented.</p><p><strong>Results: </strong>97 152 patients were included. The 42-day POE rates for secondary IOL implantation for aphakia and for IOL exchange were 0.35% and 0.28% overall, 0.31% and 0.30% when combined with posterior vitrectomy, and 0.84% and 0.42% with anterior vitrectomy, respectively. The risk of POE increased when secondary IOL surgery was combined with anterior vitrectomy compared with no vitrectomy (adjusted odds ratio [aOR], 1.849; P < .001) and with higher Charlson Comorbidity Indexes compared with 0: 1 to 2 (aOR, 1.495; P = .01), 3 to 4 (aOR, 1.591; P = .01), 5 to 6 (aOR, 1.617; P = .046), and ≥7 (aOR, 3.290; P < .001). Risk was decreased for IOL exchange compared with secondary IOL implantation for preoperative aphakia (aOR, 0.783; P = .04).</p><p><strong>Conclusions: </strong>The overall POE rate for all secondary IOL surgeries was 0.31% during the 11-year period. We hypothesize that the absence of the posterior capsular barrier would explain the higher POE rates compared with cataract surgery, especially if a concurrent vitrectomy was performed with the secondary IOL procedure.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"91-97"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of measurement variability across automated biometry devices.","authors":"J Morgan Micheletti, Brad Hall","doi":"10.1097/j.jcrs.0000000000001583","DOIUrl":"10.1097/j.jcrs.0000000000001583","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate measurement variability between different readily available automated biometric devices for the purposes of improving surgeon decision-making for phakic intraocular lens (IOL) sizing.</p><p><strong>Setting: </strong>Private practice (Houston, Texas).</p><p><strong>Design: </strong>Prospective, single-center, bilateral, nonrandomized, open-label, observational study.</p><p><strong>Methods: </strong>This study included healthy eyes, with no prior eye surgery, and with a spherical equivalent of at least -1.00 diopter. Orbscan II was compared with Argos, Atlas 9000, caliper, IOLMaster 500, IOLMaster 700, iTrace, Lenstar LS900, Pentacam HR, and Pentacam AXL Wave. Preoperative measurements included white-to-white (WTW), anterior chamber depth (ACD), and central corneal thickness (CCT). Linear mixed-effect models were created to determine adjustment factor between the Orbscan II and other devices for WTW, ACD, and CCT measurements.</p><p><strong>Results: </strong>204 participants (408 eyes) completed the study. All mean WTW measurements were significantly different compared with the Orbscan II ( P < .01), except for Pentacam AXL Wave. All mean ACD and CCT measurements were significantly different compared with the Orbscan II ( P < .01). Adjustment factors for WTW ranged from -0.65 to 0.24 mm. Adjustment factors for ACD ranged from -0.21 to -0.16 mm. Adjustment factors for CCT ranged from 19.9 to -36.0 μm.</p><p><strong>Conclusions: </strong>The biometers tested were not interchangeable with the Orbscan II. Adjustment factors for WTW and ACD may compensate for differences between devices and adapt ICL sizing recommendations.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"156-160"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal outcomes of iStent inject with cataract surgery compared with cataract surgery alone: real-world data from the Fight Glaucoma Blindness registry.","authors":"Colin I Clement, Vuong Nguyen, Frank Howes, Jenny Danks, Vincent Lee, David Wechsler, Emily Gregory-Roberts, Mark Gillies, Mitchell Lawlor","doi":"10.1097/j.jcrs.0000000000001567","DOIUrl":"10.1097/j.jcrs.0000000000001567","url":null,"abstract":"<p><strong>Purpose: </strong>To compare combined phacoemulsification and iStent inject with phacoemulsification alone.</p><p><strong>Setting: </strong>Fight Glaucoma Blindness (FGB) registry, Sydney, Australia.</p><p><strong>Design: </strong>Prospective observational registry study.</p><p><strong>Methods: </strong>Eyes that had combined phacoemulsification with iStent inject (iStent group), n = 1257 were compared with eyes that had phacoemulsification only (cataract alone, n = 163). The primary outcome was percentage of eyes achieving >20% intraocular pressure (IOP) reduction from baseline 12 months postoperatively. Secondary outcomes included mean IOP and medication reduction, adverse events, and secondary procedures.</p><p><strong>Results: </strong>At 12 months, the percentage of eyes achieving >20% reduction of IOP was significantly higher in the iStent group compared with the cataract-alone group (40.9% vs 30.1% P < .001). Adverse events occurred at a low rate in both groups, and secondary IOP-lowering procedures were significantly less frequent in the iStent group compared with cataract alone.</p><p><strong>Conclusions: </strong>Real-world outcomes from the FGB registry at 12 months show that phacoemulsification combined with iStent inject has a higher efficacy and reduced need for secondary IOP-lowering surgery compared with phacoemulsification alone.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"113-118"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing optical quality and simulated defocus curves: head-to-head analysis of hydrophilic and hydrophobic trifocal intraocular lenses.","authors":"Grzegorz Łabuz, Weijia Yan, Ramin Khoramnia, Gerd U Auffarth","doi":"10.1097/j.jcrs.0000000000001577","DOIUrl":"10.1097/j.jcrs.0000000000001577","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the optical function of the new AT ELANA trifocal intraocular lens (IOL) made of hydrophobic material against an equivalent version made of hydrophilic material.</p><p><strong>Setting: </strong>David J Apple Center for Vision Research, Heidelberg, Germany.</p><p><strong>Design: </strong>Laboratory investigation.</p><p><strong>Methods: </strong>This optical investigation was conducted on +20 diopter (D) samples of the AT ELANA and AT LISA tri. The area under the modulation transfer function (MTFa) served as a quality criterion. Simulated visual acuity (VA) and defocus curves across +1 to -3.5 D range were derived from an empirical formula according to ANSI Z80.35. Susceptibility to photic phenomena was evaluated by assessing the light distribution around a point light source.</p><p><strong>Results: </strong>The 2 models demonstrated comparable optical quality. While at distance, a 4% improvement was noted with the AT LISA tri, the AT ELANA's near MTFa was 5% higher. Only a marginal difference (1%) was noted at intermediate. Both IOLs reached simulated VA of 0.0 logMAR far vision, 0.10 logMAR at 80 cm, and 0.05 logMAR at 40 cm. Still, the near range was slightly expanded with the hydrophobic model. The light-spread profile was comparable between the 2 trifocals.</p><p><strong>Conclusions: </strong>The AT ELANA and AT LISA tri demonstrated comparable optical quality and similarities in the potential for inducing photic phenomena. This study suggests that the hydrophobic trifocal IOL may provide visual range comparable with its hydrophilic counterpart. However, the asphericity change may facilitate the selection of a model that more effectively addresses specific corneal aberrations.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"161-166"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142562470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing visual outcomes of keratorefractive lenticule extraction, PRK, and LASIK procedures in the military population.","authors":"Charisma B Evangelista, Justin P Harris, Toan M Trinh, Paul D Kohler, Ryan Mackie, Sergei Turovets, James K Aden, Jose E Capo-Aponte","doi":"10.1097/j.jcrs.0000000000001565","DOIUrl":"10.1097/j.jcrs.0000000000001565","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the 6-month visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) as compared with laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in a military population at a Joint Warfighter Refractive Surgery Center.</p><p><strong>Setting: </strong>Joint Warfighter Refractive Surgery Center (JWRSC), Lackland Air Force Base, San Antonio, Texas.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Methods: </strong>Patients who underwent KLEx, PRK, or LASIK between 2019 and 2022 were included. Anonymized data collected included demographics, preoperative and postoperative uncorrected and corrected visual acuity, and manifest refraction.</p><p><strong>Results: </strong>Of the 4466 treated eyes, 737 (16.5%) underwent the KLEx, 2801 (62.7%) underwent PRK, and 928 (20.8%) underwent LASIK treatment. Regarding efficacy, there was no statistically significant difference at postoperative month (POM) 6 between the percentage of eyes reaching an uncorrected distance visual acuity of 20/20 or better between the 3 procedures. At POM1 ( P < .001) and POM3 ( P < .001), there were a greater number of eyes in the KLEx group that achieved the same or 1 line better of distance visual acuity than the PRK group. The efficacy indices of KLEx, PRK, and LASIK at POM6 were 1.09, 1.10, and 0.97, respectively. The safety indices for KLEx, PRK, and LASIK at POM6 were 0.96, 1.01, and 0.81, respectively.</p><p><strong>Conclusions: </strong>After the initial recovery period, KLEx demonstrates comparable outcomes in efficacy, safety, and accuracy as compared with LASIK and PRK.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"98-105"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical corneal effects of LASIK Xtra compared with conventional FS-LASIK in high myopic eyes.","authors":"Klemens Paul Kaiser, Marvin Lucas Biller, Tyll Jandewerth, Petra Davidova, Eva Hemkeppler, Christoph Lwowski, Myriam Böhm, Thomas Kohnen","doi":"10.1097/j.jcrs.0000000000001566","DOIUrl":"10.1097/j.jcrs.0000000000001566","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the in vivo corneal biomechanical response to FS-LASIK combined with accelerated corneal crosslinking (LASIK Xtra) compared with conventional FS-LASIK (convLASIK) in highly myopic eyes.</p><p><strong>Setting: </strong>Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany.</p><p><strong>Design: </strong>Prospective, randomized fellow eye-controlled clinical trial.</p><p><strong>Methods: </strong>Patients who received treatment with LASIK Xtra (30mW/cm 2 , 90 seconds with continuous UV-A) in 1 eye and convLASIK in the other eye were enrolled. Both eyes were subjected preoperatively and 12 months postoperatively to a Corvis ST examination. The stiffness parameter at first applanation (SP-A1), integrated inverse radius (IIR), deformation amplitude (DA), deformation amplitude 2 mm away from apex, and the apical deformation (DARatio2mm) were evaluated.</p><p><strong>Results: </strong>The study included 38 high myopic eyes (-7.34 ± 1.02 diopters) of 19 patients. The results of the corneal biomechanical measurement showed a significant reduction in overall corneal stiffness with a significant decrease in postoperative SP-A1 and increase in IIR, DA, and DARatio2mm ( P < .001). In a direct comparison, there was no evidence of an increase in corneal stiffness in the LASIK Xtra group compared with the convLASIK group 12 months postoperatively. No statistically significant difference was detected in any of the 4 biomechanical parameters ( P > .05).</p><p><strong>Conclusions: </strong>The corneal biomechanical response to convLASIK and LASIK Xtra did not vary significantly. With a similar corneal thickness loss, there was no significant difference in the 4 biomechanical metrics between the convLASIK and LASIK Xtra groups. Thus, LASIK Xtra appeared not to have a protective corneal stiffening effect compared with convLASIK 12 months postoperatively.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"106-112"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}