Journal of cataract and refractive surgery最新文献

{"title":"Comparison of intraocular lens power formulas for negative-diopter intraocular lens implantation for high myopia.","authors":"Woong-Joo Whang, Kyungmin Koh, Kenneth J Hoffer, Domenico Schiano-Lomoriello, Enrico Lupardi, Leonardo Taroni, Hungwon Tchah, Giacomo Savini","doi":"10.1097/j.jcrs.0000000000001569","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001569","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the accuracy of intraocular lens (IOL) power calculation formulas for myopic eyes requiring negative diopter powered IOLs.</p><p><strong>Design: </strong>Retrospective case series.</p><p><strong>Setting: </strong>K… hospital and Y… Hospital, …, ….</p><p><strong>Methods: </strong>Sixty-one eyes that underwent phacoemulsification with implantation of a negative power IOL were investigated. The trueness, precision and accuracy of IOL power calculation were assessed for the Barrett Universal II (BUII), EVO 2.0, Haigis, Hoffer QST, Holladay 1 and SRK/T formulas using the Eyetemis online tool. The analysis was performed using 1) the ULIB IOL constants and 2) after constant optimization.</p><p><strong>Results: </strong>With ULIB constants, the Haigis, Holladay 1 and SRK/T resulted in a hyperopic mean prediction error (PE) >1.00 diopter (D), which was significantly different from zero (adjusted p <0.05). The mean PE of the remaining formulas was closer to zero. The absolute PE was significantly higher with the Holladay 1 and SRK/T (adjusted p <0.05) with respect to the remaining formulas. After constant optimization, the outcomes of traditional formulas improved and no statistically significant differences were found among any of the formulas in terms of trueness, precision and accuracy. The percentage of eyes with an absolute PE within 0.50 D was low (<50%) even after constant optimization.</p><p><strong>Conclusions: </strong>With ULIB constants, the BUII, EVO 2.0 and Hoffer QST were more accurate than traditional formulas in eyes with negative-diopter IOLs. The results of IOL power calculation in these eyes remain poor even after constant optimization.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal outcomes of iStent inject with cataract surgery compared to cataract surgery alone: real-world data from the Fight Glaucoma Blindness registry.","authors":"Colin I Clement, Vuong Nguyen, Frank Howes, Jenny Danks, Vincent Lee, David Wechsler, Emily Gregory Roberts, Mark Gillies, Mitchell Lawlor","doi":"10.1097/j.jcrs.0000000000001567","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001567","url":null,"abstract":"<p><strong>Purpose: </strong>To compare combined phacoemulsification and iStent inject to phacoemulsification alone.</p><p><strong>Setting: </strong>Fight Glaucoma Blindness (FGB) registry - Australia.</p><p><strong>Design: </strong>Prospective observational registry study.</p><p><strong>Methods: </strong>Eyes that had combined phacoemulsification with iStent inject (iStent group) were compared to eyes that had phacoemulsification only (cataract alone). Primary outcome was percentage of eyes achieving >20% IOP reduction from baseline 12 months after surgery. Secondary outcomes included mean IOP and medication reduction, adverse events and secondary procedures.</p><p><strong>Results: </strong>At 12 months the percentage of eyes achieving >20% reduction of IOP at 12 months was significantly higher in the iStent group compared to the cataract alone group (40.9% vs 30.1% p<0.001). Adverse events occurred at a low rate in both groups, and secondary IOP lowering procedures were significantly less frequent in the iStent group compared to cataract alone.</p><p><strong>Conclusions: </strong>Real-world outcomes from the FGB registry at 12 months show phacoemulsification combined with iStent inject has higher efficacy and a reduced need for secondary IOP lowering surgery compared to phacoemulsification alone.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endophthalmitis Rates following Secondary Intraocular Lens Surgeries: An 11-year Medicare Fee-For-Service Analysis.","authors":"Caroline H Kerrison, David F Chang, Chen Dun, Jasdeep Sabharwal, Fasika A Woreta","doi":"10.1097/j.jcrs.0000000000001563","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001563","url":null,"abstract":"<p><strong>Purpose: </strong>To assess postoperative endophthalmitis (POE) rates and risk factors after secondary intraocular lens (IOL) implantation for preoperative aphakia and IOL exchange combined with or without vitrectomy.</p><p><strong>Setting: </strong>Medicare fee for service (FFS) beneficiaries, United States.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Methods: </strong>Medicare FFS beneficiaries who underwent IOL exchange or secondary IOL implantation for preoperative aphakia between January 1, 2011 - November 19, 2022 were identified. POE rates were calculated overall and separately for each surgical category - secondary IOL for aphakia versus IOL exchange, with subsets for concurrent anterior or posterior vitrectomy. Multi-variate analysis of potential risk factors was implemented.</p><p><strong>Results: </strong>97,152 patients were included. The 42-day POE rates for secondary IOL implantation for aphakia and for IOL exchange were 0.35% and 0.28% overall, 0.31% and 0.30% when combined with posterior vitrectomy, and 0.84% and 0.42% with anterior vitrectomy. The risk of POE increased when secondary IOL surgery was combined with anterior vitrectomy compared to no vitrectomy (adjusted odds ratio [aOR] 1.849; p<0.001) and with higher Charlson comorbidity indexes compared to 0: 1-2 (aOR 1.495; p=0.01), 3-4 (aOR 1.591; p=0.01), 5-6 (aOR 1.617; p=0.046), ≥7 (aOR 3.290; p<0.001). Risk was decreased for IOL exchange compared to secondary IOL implantation for preoperative aphakia (aOR 0.783; p=0.04).</p><p><strong>Conclusion: </strong>The overall POE rate for all secondary IOL surgeries was 0.31% during the 11-year period. We hypothesize that absence of the posterior capsular barrier would explain the higher POE rates compared with cataract surgery, especially if a concurrent vitrectomy was performed with the secondary IOL procedure.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Visual Outcomes of KLEx, PRK, and LASIK Procedures in the Military Population.","authors":"Charisma B Evangelista, Justin P Harris, Toan M Trinh, Paul D Kohler, Ryan Mackie, Sergei Turovets, James K Aden, Jose E Capo-Aponte","doi":"10.1097/j.jcrs.0000000000001565","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001565","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the 6-month visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) as compared to laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in a military population at a Joint Warfighter Refractive Surgery Center.</p><p><strong>Setting: </strong>Joint Warfighter Refractive Surgery Center (JWRSC), Lackland Air Force Base, San Antonio, TX.</p><p><strong>Design: </strong>Retrospective Study.</p><p><strong>Methods: </strong>Patients who underwent either KLEx, PRK, or LASIK between 2019-2022 were included. Anonymized data collected included demographics, pre- and post-operative uncorrected and corrected visual acuity, and manifest refraction.</p><p><strong>Results: </strong>Of the 4,466 treated eyes, 737 (16.5%) underwent the KLEx, 2,801 (62.7%) underwent PRK, and 928 (20.8%) underwent LASIK treatment. In terms of efficacy, there was no statistically significant difference at post-operative month (POM)6 between the percentage of eyes reaching an uncorrected distance visual acuity (UDVA) of 20/20 or better between the three procedures. At POM1 (P < 0.001) and POM3 (P < 0.001), there were a greater number of eyes in the KLEx group that achieved the same or 1 line better of distance visual acuity than the PRK group. The efficacy index of KLEx, PRK, and LASIK at POM6 were 1.09, 1.10, and 0.97, respectively. The safety index for KLEx, PRK, and LASIK at POM6 were 0.96, 1.01, and 0.81, respectively.</p><p><strong>Conclusions: </strong>After the initial recovery period, KLEx demonstrates comparable outcomes in terms of efficacy, safety, and accuracy as compared to LASIK and PRK.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical Corneal Effects of LASIK-Xtra Compared to Conventional Femto-LASIK in High Myopic Eyes.","authors":"Klemens Paul Kaiser, Marvin Lucas Biller, Tyll Jandewerth, Petra Davidova, Eva Hemkeppler, Christoph Lwowski, Myriam Böhm, Thomas Kohnen","doi":"10.1097/j.jcrs.0000000000001566","DOIUrl":"10.1097/j.jcrs.0000000000001566","url":null,"abstract":"<p><strong>Purpose: </strong>This study seeks to investigate the in vivo corneal biomechanical response to femtosecond laser-assisted in situ keratomileusis (FS-LASIK) combined with accelerated corneal crosslinking (LASIK-Xtra) compared to conventional FS-LASIK (convLASIK) in highly myopic eyes.</p><p><strong>Setting: </strong>Department of Ophthalmology, Goethe-University, Frankfurt, Germany.</p><p><strong>Design: </strong>A prospective, randomized fellow eye-controlled clinical trial.</p><p><strong>Methods: </strong>We enrolled patients who received treatment with LASIK-Xtra (30mW/cm 2 , 90 seconds with continuous UVA) in one eye and convLASIK in the fellow eye. Both eyes were subjected preoperatively and twelve months postoperatively to a Corvis ST examination. The stiffness parameter at first applanation (SP-A1), integrated inverse radius (IIR), deformation amplitude (DA), deformation amplitude 2 mm away from apex and the apical deformation (DARatio2mm) were evaluated.</p><p><strong>Results: </strong>The study included 38 high myopic eyes (-7.34±1.02 diopter) of 19 patients. The results of the corneal biomechanical measurement showed a significant reduction in overall corneal stiffness with a significant decrease in postoperative SP-A1 and increase in IIR, DA, and DARatio2mm (p<.001). In a direct comparison, there was no evidence of an increase in corneal stiffness in the LASIK-Xtra group compared to the convLASIK group twelve months postoperatively. No statistically significant difference was detected in any of the four biomechanical parameters (p>.05).</p><p><strong>Conclusion: </strong>The corneal biomechanical response to convLASIK and LASIK-Xtra did not vary significantly. With a similar corneal thickness-loss, there was no significant difference in the four biomechanical metrics between the convLASIK and LASIK-Xtra groups. Thus, LASIK-Xtra seems not to have a protective corneal stiffening effect compared to convLASIK twelve months postoperatively.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Power profile and optical performance of two extended range-of-vision intraocular lens designs.","authors":"Fidel Vega, Nuria Garzón, María García-Montero, María S Millán","doi":"10.1097/j.jcrs.0000000000001528","DOIUrl":"10.1097/j.jcrs.0000000000001528","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the power profile and optical performance of 2 extended range-of-vision (ERV) intraocular lenses (IOLs), TECNIS Eyhance (ICB00) and LuxSmart, and compare them with their monofocal counterpart lenses with similar platforms and materials: TECNIS 1-piece (ZCB00) and LuxGood, respectively.</p><p><strong>Setting: </strong>Optics and Optometry Faculties of Complutense University (Madrid) and Universitat Politècnica de Catalunya BarcelonaTech (Terrassa) in Spain.</p><p><strong>Design: </strong>Laboratory investigation on optical bench.</p><p><strong>Methods: </strong>For each design, the power distribution and (fourth and sixth-order) spherical aberration (SA) across the lens aperture were measured as well as the optical performance using modulation transfer function-based metrics with through-focus evaluation. 3 nominal powers (+10.00 diopters [D], +20.00 D, and +30.00 D) and 3 pupil sizes (2.0 mm, 3.0 mm, and 4.5 mm) were considered to assess whether the base power of the lens and pupillary dynamics have an influence on the depth-of-focus extension.</p><p><strong>Results: </strong>TECNIS Eyhance and LuxSmart IOLs had different power and SA profiles, but both designs shared a positive add power in their central region in comparison with their monofocal counterparts. LuxSmart had a greater add power while TECNIS Eyhance showed higher peak optical quality but smaller depth of focus.</p><p><strong>Conclusions: </strong>Differences of focus extension between the 2 ERV IOL designs are related to differences of power and SA profile. The nominal base power of the IOLs has little effect on their optical quality. However, pupil dynamics plays a key role since it determines the effective add power and optical performance of the ERV IOLs.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"1065-1073"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural integrity of eyelets in a hydrophobic intraocular lens with four-point scleral fixation.","authors":"Zi Jin, André S Pollmann, R Rishi Gupta, Adrian T Fung","doi":"10.1097/j.jcrs.0000000000001527","DOIUrl":"10.1097/j.jcrs.0000000000001527","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"1092-1093"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of the relationship between the severity of posterior capsular opacification detected by objective detection techniques and visual acuity.","authors":"Ziyue Song, Zhigang Chen, Caixin Li, Yanting Li, Yueqi Liu, Peirong Lu","doi":"10.1097/j.jcrs.0000000000001494","DOIUrl":"10.1097/j.jcrs.0000000000001494","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the severity of posterior capsule opacification (PCO) using objective detection techniques and its relationship with visual acuity.</p><p><strong>Setting: </strong>The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.</p><p><strong>Design: </strong>Prospective cohort study.</p><p><strong>Methods: </strong>All patients underwent slitlamp examination, intraocular pressure (IOP) measurement, and corrected distance visual acuity (CDVA) testing before Nd:YAG laser capsulotomy, and examination, after fully dilated, with: IOLMaster 700, optical coherence tomography (OCT), Sirius Topographer (CSO) anterior segment analysis, and color fundus photography (CFP). CDVA and IOP were taken post treatment. Thickness and density of the posterior capsule, CFP quality (CFPQ) and OCT signal strength (OCTSS) were recorded. Analysis used Spearman correlation, heatmaps, and receiver operating characteristic curves.</p><p><strong>Results: </strong>83 eyes in 78 patients were included in this study. Spearman correlation analysis revealed correlations between pretreatment CDVA and IOLMaster 700 PCO thickness (MT), IOLMaster 700 cumulative effect (MCE), Sirius PCO thickness (ST), Sirius maximum density (SMD), Sirius cumulative effect (SCE), OCTSS, and CFPQ (correlation coefficients were 0.500, 0.484, 0.465, -0.256, 0.317, -0.442, -0.412, all P < .05). The improvement of vision acuity (ImpVA) showed correlations with MT, MCE, ST, SCE, OCTSS, and CFPQ (correlation coefficients were -0.452, -0.471, -0.346, -0.278, 0.320, 0.381, all P < .05). For ImpVA, the predictive ability of IOLMaster 700 was superior to Sirius, and the joint model was significantly better than single factors.</p><p><strong>Conclusions: </strong>Posterior capsule thickness and cumulative effect were reliable indicators for evaluating PCO. Compared with Sirius, the IOLMaster 700 demonstrated superior predictive ability and higher correlation.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"1020-1025"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141086664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness and safety of a novel crosslinked hyaluronate canalicular gel occlusive device for dry eye.","authors":"Mark Packer, Richard Lindstrom, Vance Thompson, Jai G Parekh, Preeya Gupta, Lisa M Nijm, Eric Donnenfeld","doi":"10.1097/j.jcrs.0000000000001505","DOIUrl":"10.1097/j.jcrs.0000000000001505","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effectiveness and safety of a crosslinked hyaluronate (HA) canalicular filler (Lacrifill Canalicular Gel) compared with a commercially available hydrogel canalicular plug (Form Fit).</p><p><strong>Setting: </strong>5 sites in the United States.</p><p><strong>Design: </strong>Prospective, multicenter, controlled, double-masked, randomized 2:1 (filler:plug).</p><p><strong>Methods: </strong>Adults (≥22 years) with the Schirmer test (with anesthesia) ≤10 mm/5 minutes, presence of corneal staining, ocular surface disease index (OSDI) of ≥23 with ≤3 responses of \"not applicable,\" patent lacrimal drainage system, and bilateral corrected distance visual acuity of 20/40 or better. Filler or plugs were instilled bilaterally in the inferior canaliculi. Primary effectiveness endpoint was noninferiority of the mean within subject change from baseline to month 3 in Schirmer score for patients receiving filler compared with plugs. The key secondary effectiveness endpoint was noninferiority of the proportion of patients with filler achieving improvement from baseline to month 3 in OSDI by a minimal clinically important difference. Additional endpoints included the mean change from baseline to 3 and 6 months in tear meniscus height, OSDI, corneal staining, tear breakup time, and safety.</p><p><strong>Results: </strong>157 patients were randomized; 99 patients with crosslinked HA filler and 52 patients with hydrogel plugs completed the study. Filler was noninferior to plugs in the mean Schirmer score change from baseline and in the proportion of patients achieving a clinically important improvement in OSDI.</p><p><strong>Conclusions: </strong>Crosslinked HA filler is a safe, well-tolerated, and effective method to treat dry eye. Clinically and statistically significant improvements in signs and symptoms of dry eye were sustained through 6 months.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"1051-1057"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141320873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reusing surgical materials for cataract surgery: an assessment of potential contamination.","authors":"Aakriti Garg Shukla, David F Chang, Thamizhselvi Dhanaseelan, Vellam Ramakrishnan Vivekanandan, Joseph Gubert, Alan L Robin, Rengaraj Venkatesh","doi":"10.1097/j.jcrs.0000000000001509","DOIUrl":"10.1097/j.jcrs.0000000000001509","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate microbiological cultures of cataract surgical devices and products that were reused for multiple cases.</p><p><strong>Setting: </strong>Aravind Eye Hospital, Pondicherry, Tamil Nadu, India.</p><p><strong>Design: </strong>Prospective cohort study.</p><p><strong>Methods: </strong>Samples from multiple surgical instruments and products that were reused for consecutive cataract surgeries underwent bacterial and fungal cultures and were monitored alongside positive controls for 7 days. This included instruments that were processed using immediate use steam sterilization (IUSS) between cases (eg, surgical cannulas, syringes, phacoemulsification and coaxial/bimanual irrigation/aspiration [I/A] tips, phacoemulsification and I/A sleeves) (Group 1), instruments that were used without sterilization between cases (eg, phacoemulsification tubing/handpieces, coaxial I/A handpieces) (Group 2), and the residual (unused) fluid from balanced salt solution bags after being used for multiple patients (Group 3).</p><p><strong>Results: </strong>3333 discrete samples were collected from all 3 product groups that were reused across multiple patients. In all collected samples, no bacterial or fungal growth was observed. Of the 3241 cataract surgeries that used reused and IUSS-sterilized instruments alongside instrument sets cultured on the same day and balanced salt solution bags shared across multiple patients, no eyes developed endophthalmitis over a 6-week follow-up period.</p><p><strong>Conclusions: </strong>Bacterial or fungal growth was not found in extensive microbiological cultures of IUSS-sterilized ophthalmic surgical instruments and cataract surgical products that were reused in multiple patients. This microbiological data complements clinical endophthalmitis data from 2 million consecutive cases at the Aravind Eye Hospital, suggesting that their instrument and surgical supply processing practices may allow for safe and sustainable ophthalmic care.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"993-999"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141446247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}