Journal of cataract and refractive surgery最新文献

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Optimization of crystalline lens refractive index to improve the accuracy of intraocular lens power calculation in patients with dense cataract. 优化晶状体折射率以提高密闭性白内障患者人工晶状体度数计算的准确性。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 DOI: 10.1097/j.jcrs.0000000000001941
Tsuyoshi Nogami, Takashi Kojima, Akeno Tamaoki, Ayako Sawaki, Asato Hasegawa, Tatsushi Kaga
{"title":"Optimization of crystalline lens refractive index to improve the accuracy of intraocular lens power calculation in patients with dense cataract.","authors":"Tsuyoshi Nogami, Takashi Kojima, Akeno Tamaoki, Ayako Sawaki, Asato Hasegawa, Tatsushi Kaga","doi":"10.1097/j.jcrs.0000000000001941","DOIUrl":"10.1097/j.jcrs.0000000000001941","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate effects of crystalline lens refractive index (LRI) on prediction error (PE) and suggest the optimal LRI in cases of dense cataract.</p><p><strong>Setting: </strong>Chukyo Hospital, Aichi, Japan.</p><p><strong>Design: </strong>Retrospective consecutive case series study.</p><p><strong>Methods: </strong>Patients who underwent cataract surgery were enrolled and allocated into Group A (nuclear hardness ≤III) and B (nuclear hardness ≥IV) based on the Emery-Little classification. The swept-source optical biometer was used for biometric measurements. Assuming the postoperative axial length (AL) to be the valid value, a corrected LRI (CLRI) was calculated to make the preoperative AL equivalent to the postoperative one. In the validation group, the PE of the SRK/T formula and Barrett Universal II (BUII) were evaluated using the precorrection and postcorrection refractive indices.</p><p><strong>Results: </strong>Of the 5196 enrolled eyes, 1084 were evaluated. In Group A, there was no significant difference between the preoperative and postoperative ALs ( P = .07). In Group B, the mean postoperative AL (24.09 ± 2.05 mm) was significantly shorter than the mean preoperative AL (24.12 ± 2.06 mm) ( P < .001). The average CLRI in Group A and B were 1.41 and 1.42, respectively. In the validation group, the PEs using CLRI (SRK/T, 0.10 ± 0.48 diopters [D]; BUII, 0.03 ± 0.35 D) were significantly smaller than those using LRI (SRK/T, 0.18 ± 0.49 D; BUII, 0.12 ± 0.36 D) ( P < .001).</p><p><strong>Conclusions: </strong>In cases of high lens nucleus hardness, the use of proposed CLRI demonstrated potentials for reducing PE.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"890-896"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147468052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on: Enhancing patient education in cataract surgery using a conversational artificial intelligence chatbot: pilot randomized controlled trial. 评论:使用会话人工智能聊天机器人加强白内障手术患者教育:试点随机对照试验。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 Epub Date: 2026-07-16 DOI: 10.1097/j.jcrs.0000000000002019
Henry Bair
{"title":"Comment on: Enhancing patient education in cataract surgery using a conversational artificial intelligence chatbot: pilot randomized controlled trial.","authors":"Henry Bair","doi":"10.1097/j.jcrs.0000000000002019","DOIUrl":"10.1097/j.jcrs.0000000000002019","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"949"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148455850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inferior-superior epithelial thickness difference: zone-specific analysis across topographic asymmetry. 上下上皮厚度差异:地形不对称的区域特异性分析。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 DOI: 10.1097/j.jcrs.0000000000001943
Marcony R Santhiago, Claudia R Morgado, Nicole B Larivoir, Juliana Feijó, Bianca N Susanna, Lycia P Sampaio, Andre A M Torricelli, Carla S Medeiros
{"title":"Inferior-superior epithelial thickness difference: zone-specific analysis across topographic asymmetry.","authors":"Marcony R Santhiago, Claudia R Morgado, Nicole B Larivoir, Juliana Feijó, Bianca N Susanna, Lycia P Sampaio, Andre A M Torricelli, Carla S Medeiros","doi":"10.1097/j.jcrs.0000000000001943","DOIUrl":"10.1097/j.jcrs.0000000000001943","url":null,"abstract":"<p><strong>Purpose: </strong>To assess how optical coherence tomography (OCT)-derived epithelial thickness-difference metrics relate to corneal topographic inferior-superior (I-S) asymmetry and to identify the most informative annular zones and axis-defined sector-pair metrics.</p><p><strong>Setting: </strong>University of São Paulo, Sao Paulo, Brazil.</p><p><strong>Design: </strong>Prospective, comparative observational study.</p><p><strong>Methods: </strong>In this Institutional Review Board-approved study of consecutive patients undergoing refractive surgery screening (regardless of ultimate eligibility), 526 eyes were analyzed. Axial I-S values from Placido-based topography defined 4 strata (negative, 0.0-1.0, 1.0-1.4, and >1.4 diopters [D]). 12 epithelial thickness-difference metrics (including axis-defined sector-pair differences) were computed from 9 mm OCT maps across the 2 to 5 mm, 2 to 7 mm, and 2 to 9 mm annuli. Associations between continuous I-S and each metric were tested using Pearson correlation and linear regression across the full spectrum and within analyses anchored at the clinically established I-S = 1.4 D reference.</p><p><strong>Results: </strong>The central 2 to 5 mm annulus yielded the strongest associations with I-S. Correlations were weak and slightly positive for I-S ≤1.4 D but became stronger and consistently negative for I-S >1.4 D, most prominently along the inferotemporal-superonasal (IT-SN) axis ( r = -0.62; P < .0001). Mean epithelial differences were largely similar across strata up to 1.4 D, with clearer deviations in the >1.4 D stratum.</p><p><strong>Conclusions: </strong>Using manually derived, zone-specific and axis-specific OCT epithelial thickness-difference metrics, a nonlinear association with topographic I-S was found, with the most informative signal in the central 2 to 5 mm annulus and along the IT-SN axis. Clinically, central, axis-defined epithelial asymmetry may serve as an adjunct interpretive marker in higher-I-S (or borderline) eyes, whereas low-I-S eyes show weak and variable epithelial-I-S coupling-potentially explaining the limited performance of epithelial metrics in low-asymmetry settings.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"904-911"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147529301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generative artificial intelligence for postoperative parameters prediction in implantable collamer lens surgery. 基于生成式人工智能的人工晶状体手术术后参数预测。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 DOI: 10.1097/j.jcrs.0000000000001935
Yinglin Zhang, Ruiling Xi, Lingxi Zeng, Risa Higashita, Keiichiro Okamoto, Tomoaki Nakamura, Akihito Igarashi, Seiichiro Hata, Kazunori Miyata, Kazutaka Kamiya, Jiang Liu
{"title":"Generative artificial intelligence for postoperative parameters prediction in implantable collamer lens surgery.","authors":"Yinglin Zhang, Ruiling Xi, Lingxi Zeng, Risa Higashita, Keiichiro Okamoto, Tomoaki Nakamura, Akihito Igarashi, Seiichiro Hata, Kazunori Miyata, Kazutaka Kamiya, Jiang Liu","doi":"10.1097/j.jcrs.0000000000001935","DOIUrl":"10.1097/j.jcrs.0000000000001935","url":null,"abstract":"<p><strong>Purpose: </strong>To predict multiple postoperative parameters after implantable collamer lens (ICL) surgery with generative artificial intelligence, using preoperative anterior segment optical coherence tomography (AS-OCT) images as the input.</p><p><strong>Setting: </strong>Daikanyama Eye Clinic, Tokyo, Japan; Miyata Eye Hospital, Miyazaki, Japan; Nagoya Eye Clinic, Nagoya, Japan; Yokohama Sky Eye Clinic, Kanagawa, Japan.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Methods: </strong>The research involved paired preoperative and postoperative AS-OCT images from 1010 patients (1585 eyes) who underwent horizontal ICL implantation and 86 patients (86 eyes) who received vertical implantation from 4 clinical centers. A implantable collamer lens-generative adversarial network (ICL-GAN) was used to predict postoperative structures based on preoperative AS-OCT slice from each eye. Postoperative parameters, including vault, AOD500, and TIA500, were measured from the predicted postoperative structures. The prediction error was evaluated using the mean absolute error (MAE) and root mean square error. The correlation and agreement between the prediction and the achieved values were also analyzed.</p><p><strong>Results: </strong>The vaults measured from the predictions of postoperative anatomical structure have a strong correlation with the achieved values on horizontal data ( r = 0.659, P < .01 for ICL size of 12.1 mm; r = 0.799, P < .01 for 12.6 mm; and r = 0.737, P < .01 for 13.2 mm) and when compared with the NK-formula and KS-formula achieved the minimum prediction errors (MAE are 105 μm, 114 μm, and 111 μm). ICL-GAN also performed best on the vertical implantation data. The AOD500 and TIA500 also showed good correlation and agreement with the achieved values.</p><p><strong>Conclusions: </strong>The generative artificial intelligence demonstrated the capability to predict multiple postoperative parameters after ICL surgery.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"879-884"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147432957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuroprotective and anti-inflammatory strategies for corneal nerve regeneration and ocular surface stability after corneal refractive surgeries: systematic review. 角膜屈光手术后角膜神经再生和眼表稳定性的神经保护和抗炎策略:系统综述。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 DOI: 10.1097/j.jcrs.0000000000001933
Anas Alamoudi, Abdulaziz Khalid Aldahlawi, Ahmed Alnabihi, Rozan Abdulaziz AlGhamdi, Hind Mohammed Aljabri, Naif Almufarriji, Rahaf Khder Sharif, Danah Albreiki, Bader AlQahtani
{"title":"Neuroprotective and anti-inflammatory strategies for corneal nerve regeneration and ocular surface stability after corneal refractive surgeries: systematic review.","authors":"Anas Alamoudi, Abdulaziz Khalid Aldahlawi, Ahmed Alnabihi, Rozan Abdulaziz AlGhamdi, Hind Mohammed Aljabri, Naif Almufarriji, Rahaf Khder Sharif, Danah Albreiki, Bader AlQahtani","doi":"10.1097/j.jcrs.0000000000001933","DOIUrl":"10.1097/j.jcrs.0000000000001933","url":null,"abstract":"<p><strong>Topic: </strong>This study aimed to systematically synthesize and critically appraise all controlled trials evaluating neuroprotective and anti-inflammatory pharmacotherapies for enhancing corneal nerve regeneration and ocular surface stability after corneal refractive surgeries.</p><p><strong>Clinical relevance: </strong>Postrefractive surgery dry eye and hypoesthesia are common and often persistent, underscoring the need for evidence-based pharmacologic strategies to promote corneal nerve recovery and tear film stability.</p><p><strong>Methods: </strong>The authors registered a PROSPERO-guided protocol (CRD42024610462) and systematically searched Clinicaltrials.gov, CENTRAL, Google scholar, Medline from inception to March 2025 for randomized controlled trials (RCTs) evaluating neuroprotective or anti-inflammatory pharmacotherapies after laser-assisted in situ keratomileusis (LASIK), photorefractive keratectomy (PRK), laser-assisted subepithelial keratectomy, or femto-LASIK. 2 independent reviewers screened records, extracted data, and assessed risk of bias using the Cochrane Risk of Bias 2 tool.</p><p><strong>Results: </strong>7 trials (n = 484 participants/eyes, 6 countries) met eligibility. Topical cyclosporine 0.05% (2 RCTs) consistently hastened flap sensitivity recovery (Δ + 4 cm at 3 months) and improved 6-month ocular surface metrics (ocular surface disease index -5 points; tear breakup time [TBUT] +4 seconds; Schirmer +5.5 mm; P < .001). Topical chloroquine 0.03% produced similar but smaller gains. Topical diclofenac 0.1% reduced PRK pain by ∼50% within 24 hours without delaying epithelial closure. Topical citicoline 1% accelerated sensory normalization by 2 weeks and transiently enhanced Schirmer/TBUT, whereas autologous platelet-rich plasma reduced epithelial staining but did not affect nerve density. Oral pregabalin (150 mg 2 times a day) and oral gabapentin (300 mg perioperatively) reduced first-week pain after surface ablation yet had no measurable impact on nerve metrics or dry eye indices through 6 months.</p><p><strong>Conclusions: </strong>Among tested strategies, topical cyclosporine provides the strongest evidence for enhancing corneal nerve function and long-term tear film stability after refractive surgery. However, overall evidence remains limited. Larger, double-masked trials with extended follow-up are needed to further elucidate the roles of these interventions.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"936-942"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147432994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interexpert agreement on epithelial thickness mapping for refractive surgery screening: variability highlights need for standardization. 屈光手术筛查上皮厚度映射的专家间协议:可变性突出了标准化的必要性。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 DOI: 10.1097/j.jcrs.0000000000001928
Niklas Mohr, Jorge L Alio Del Barrio, Martin Dirisamer, Alain Saad, Stefan Kassumeh, Wolfgang J Mayer, Siegfried G Priglinger, Nikolaus Luft
{"title":"Interexpert agreement on epithelial thickness mapping for refractive surgery screening: variability highlights need for standardization.","authors":"Niklas Mohr, Jorge L Alio Del Barrio, Martin Dirisamer, Alain Saad, Stefan Kassumeh, Wolfgang J Mayer, Siegfried G Priglinger, Nikolaus Luft","doi":"10.1097/j.jcrs.0000000000001928","DOIUrl":"10.1097/j.jcrs.0000000000001928","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate interexpert agreement on epithelial thickness map interpretation and its influence on eligibility decisions for keratorefractive surgery candidates.</p><p><strong>Setting: </strong>Multicenter international collaboration involving 4 experienced refractive surgeons.</p><p><strong>Design: </strong>Retrospective, masked case review study.</p><p><strong>Methods: </strong>A total of 103 cases were retrospectively evaluated, including patients with normal (n = 44), borderline (n = 44), and keratoconic (n = 15) corneal tomography, as defined by the Belin-Ambrosio display (BAD). 4 independent experts (M.D., J.L.A.d.B., A.S., and N.L.) first assessed surgical eligibility based on Scheimpflug tomography and subsequently re-evaluated the same cases with the addition of anterior segment optical coherence tomography-based epithelial thickness maps. To ensure comparability, a standardized questionnaire with 9 predefined epithelial thickness characteristics was used. Interrater agreement was quantified with Fleiss κ, and the relative impact of each imaging modality on decision-making was ranked.</p><p><strong>Results: </strong>Incorporating epithelial mapping changed the eligibility decision in 19% (77/412) of cases. Specifically, 9% (16/176) of normal, 20% (35/176) of borderline, and 3% (2/60) of keratoconic cases were reclassified as eligible, while 2% (3/176), 6% (10/176), and 3% (2/60), respectively, were deemed ineligible. Interrater agreement on eligibility was moderate before (κ = 0.46) and after (κ = 0.43) adding epithelial maps but remained poor in borderline cases (κ = 0.14 and 0.12, respectively). Agreement on epithelial profile features ranged from poor to fair (κ = -0.78 to 0.35). Corneal topography and BAD were ranked as most influential, followed by epithelial mapping.</p><p><strong>Conclusions: </strong>Epithelial mapping frequently shifted decisions toward eligibility. However, poor interexpert agreement highlights the need for standardized, safety-oriented interpretation to ensure consistent ectasia risk assessment before refractive surgery.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"865-871"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147306193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual and refractive outcomes with intrascleral haptic fixation of the light adjustable lens. 可调光晶状体巩膜内触觉固定的视力和屈光效果。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 DOI: 10.1097/j.jcrs.0000000000001936
Allison J Chen, Emily Grace Rodgers, Li Wang, Douglas D Koch, Christina Y Weng, Zaina N Al-Mohtaseb
{"title":"Visual and refractive outcomes with intrascleral haptic fixation of the light adjustable lens.","authors":"Allison J Chen, Emily Grace Rodgers, Li Wang, Douglas D Koch, Christina Y Weng, Zaina N Al-Mohtaseb","doi":"10.1097/j.jcrs.0000000000001936","DOIUrl":"10.1097/j.jcrs.0000000000001936","url":null,"abstract":"<p><strong>Purpose: </strong>To describe refractive outcomes with intrascleral haptic fixation (ISHF) of the light adjustable lens (LAL).</p><p><strong>Setting: </strong>Baylor College of Medicine and 1 private practice in the United States.</p><p><strong>Design: </strong>Retrospective sequential cohort.</p><p><strong>Methods: </strong>All patients undergoing double-needle ISHF of the LAL were included in the study. Pretreatment and post-lock-in uncorrected distance visual acuity (UDVA) were recorded. Mean numerical errors, refractive prediction errors, and astigmatism outcomes were measured.</p><p><strong>Results: </strong>10 eyes were included. Initial pretreatment UDVA after surgery ranged from 20/25 to 20/150, and post-lock-in UDVA ranged from 20/12.5 to 20/40 (median UDVA 20/20; mean 0.01 logMAR [spherical equivalent 0.04]). Mean magnitude of refractive astigmatism was 0.70 diopters (D) (range 0.00 to 1.50 D) pretreatment and 0.25 D (range 0.0 to 0.75 D) after final lock-in. Pretreatment mean numerical error was +1.00 D (SD 0.94 D) and was reduced to -0.022 D (SD 0.28) after treatments and lock-in sessions. All eyes (10/10) achieved their full visual potential in UDVA.</p><p><strong>Conclusions: </strong>This study illustrates that with careful planning and patience, patients with poor or absent capsular support who previously did not have a customizable option can potentially achieve personalized visual outcomes with excellent refractive accuracy with scleral fixation of the LAL.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"885-889"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply : Accuracy of new-generation and traditional intraocular lens power calculation formulas in pediatric primary implantation. 答:新一代与传统人工晶状体度数计算公式在小儿初级人工晶状体植入术中的准确性。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 Epub Date: 2026-06-16 DOI: 10.1097/j.jcrs.0000000000002004
Jiaxin Jin, Yanyu Shen, Yiwen Qu, Hui Chen, Xiaohang Wu, Ling Jin, Yizhi Liu, Haotian Lin, Zhenzhen Liu
{"title":"Reply : Accuracy of new-generation and traditional intraocular lens power calculation formulas in pediatric primary implantation.","authors":"Jiaxin Jin, Yanyu Shen, Yiwen Qu, Hui Chen, Xiaohang Wu, Ling Jin, Yizhi Liu, Haotian Lin, Zhenzhen Liu","doi":"10.1097/j.jcrs.0000000000002004","DOIUrl":"10.1097/j.jcrs.0000000000002004","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"953-954"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148430480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal nerve regeneration:where we are today. 角膜神经再生:我们今天的进展。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-09-01 DOI: 10.1097/j.jcrs.0000000000002024
Sathish Srinivasan
{"title":"Corneal nerve regeneration:where we are today.","authors":"Sathish Srinivasan","doi":"10.1097/j.jcrs.0000000000002024","DOIUrl":"10.1097/j.jcrs.0000000000002024","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":"52 9","pages":"841-842"},"PeriodicalIF":3.7,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small-incision lenticule extraction with prophylactic crosslinking: systematic review and meta-analysis. 预防性交联小切口晶状体摘除:系统回顾和荟萃分析。
IF 3.7 3区 医学
Journal of cataract and refractive surgery Pub Date : 2026-08-31 DOI: 10.1097/j.jcrs.0000000000002046
Kareem Sadek, Oreoluwapo Maxwell, Brendan K Tao, Isra M Hussein, Marko M Popovic, Clara C Chan
{"title":"Small-incision lenticule extraction with prophylactic crosslinking: systematic review and meta-analysis.","authors":"Kareem Sadek, Oreoluwapo Maxwell, Brendan K Tao, Isra M Hussein, Marko M Popovic, Clara C Chan","doi":"10.1097/j.jcrs.0000000000002046","DOIUrl":"10.1097/j.jcrs.0000000000002046","url":null,"abstract":"<p><strong>Topic: </strong>Keratorefractive lenticule extraction (KLEx) treats myopia and myopic astigmatism while preserving corneal biomechanics better than flap-based procedures. KLEx with prophylactic accelerated corneal crosslinking (KLEx-CXL) has been proposed for thinner corneas, higher myopia, or borderline tomography, but its incremental value remains uncertain.</p><p><strong>Clinical relevance: </strong>KLEx-CXL may reduce biomechanical instability but adds operative time, cost, and protocol variability. Comparative evidence is needed to determine whether it improves outcomes over KLEx alone.</p><p><strong>Methods: </strong>MEDLINE, Embase, Scopus, Web of Science, CENTRAL, and CINAHL were searched to July 2, 2026. Comparative adult studies with at least 6-month follow-up reporting refractive or visual outcomes were included. 2 reviewers extracted data, assessed risk of bias, and rated certainty using Grading of Recommendations, Assessment, Development, and Evaluation. Random-effects meta-analyses pooled mean differences (MDs).</p><p><strong>Results: </strong>9 studies included 730 eyes: 386 KLEx and 344 KLEx-CXL. Residual manifest refraction spherical equivalent was similar overall (MD 0.03 diopters [D]; 95% CI, -0.01 to 0.06; P = .17), with no consistent timepoint-specific difference. A small residual difference was confined to moderate-myopia cohorts (0.09 D; 95% CI, 0.04-0.15) and absent in high myopia. KLEx showed a 1-month advantage in uncorrected distance vision (MD -0.04 logMAR), safety index (MD 0.07), and efficacy index (MD 0.08), resolving by 12 months. Corrected vision was similar throughout. Biomechanical measures favored KLEx-CXL. Early haze was transient; no ectasia occurred. Certainty was low.</p><p><strong>Conclusions: </strong>KLEx and KLEx-CXL achieved similar residual refraction and corrected visual acuity. KLEx-CXL produced measurable biomechanical reinforcement but transiently delayed early uncorrected visual recovery. Current evidence supports reserving prophylactic crosslinking for higher-risk eyes.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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