Mark Packer, Tiago Monteiro, Cedric Schweitzer, Paul Rosen
{"title":"Prospective, Randomized, Controlled Multicenter Study of a Monofocal Extended Depth of Focus IOL Compared to a Standard Aspheric Monofocal IOL.","authors":"Mark Packer, Tiago Monteiro, Cedric Schweitzer, Paul Rosen","doi":"10.1097/j.jcrs.0000000000001672","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001672","url":null,"abstract":"<p><strong>Purpose: </strong>Investigate safety and effectiveness of a monofocal enhanced depth of focus intraocular lens (mono-EDoF IOL, xactTM Mono-EDoFTM Model ME4) compared to an aspheric monofocal IOL (TECNIS 1-Piece IOL Model ZCB00).</p><p><strong>Setting: </strong>Sites in United Kingdom, France, and Portugal.</p><p><strong>Design: </strong>Prospective, multicenter, controlled, single-masked, randomized 2:1 (test:control) clinical trial.</p><p><strong>Methods: </strong>Adults ≥40 years of age with bilateral cataracts, expected post-operative refractive astigmatism of ≤1.0D and calculated lens power 18D to 30D underwent implantation of either mono-EDoF or aspheric monofocal IOL in both eyes. Primary endpoints assessed at day 120-180 included monocular uncorrected distance visual acuity (UDVA) and visual disturbances. Secondary endpoints were monocular uncorrected intermediate visual acuity (UIVA) and monocular distance corrected intermediate visual acuity (DCIVA).</p><p><strong>Results: </strong>Sixty-five patients were randomized; 45 patients (95.2%) with Mono-EDoF and 20 patients (95.2%) with control completed the study. Compared with control, Mono-EDoF had significantly better monocular UDVA (P=0.0128), monocular UIVA (P<0.001), and monocular DCIVA (P<0.001). Monocular and binocular defocus curve measurements confirmed increased depth-of-focus for the Mono-EDoF compared to the control IOL by approximately 0.50D and 0.75D respectively. Contrast sensitivity measured under mesopic conditions with and without glare was similar between groups. Halo or glare was reported by 25.7% and 33.3% of patients in the Mono-EDoF group, respectively, and 22.2% and 25.0%, respectively, in the control group.</p><p><strong>Conclusions: </strong>The xact Mono-EDoF ME4 IOL is a safe and effective alternative to a monofocal IOL. It provides superior intermediate VA compared with an aspheric monofocal IOL without compromising contrast sensitivity or creating unwanted photic phenomena.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ishani P Majmudar, Harsha R Kaul, Anushree Aneja, Jasmyne E McCoy, Sahana Aggarwal, Nathan P Gill, Justin Mussman, Robert O Baker, David J Palmer, Manjot K Gill
{"title":"Videographic and Microbiologic Evaluation of Eye Drop Bottle Contamination in Clinics: A Pilot Study.","authors":"Ishani P Majmudar, Harsha R Kaul, Anushree Aneja, Jasmyne E McCoy, Sahana Aggarwal, Nathan P Gill, Justin Mussman, Robert O Baker, David J Palmer, Manjot K Gill","doi":"10.1097/j.jcrs.0000000000001670","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001670","url":null,"abstract":"<p><strong>Background: </strong>Many multidose eyedrops in the clinic and operating room are discarded after single use due to cross-contamination concerns. This practice contributes to significant hospital costs, drug shortages, and unnecessary greenhouse gas emissions.</p><p><strong>Methods: </strong>9-week, prospective, observational study of 97 patients.</p><p><strong>Objective: </strong>To validate the safety of multidose eyedrops in the ophthalmology clinic by ASORN-trained technicians using a videographic and microbiological analysis. Secondly, to determine optimal culturing conditions to prevent environmental contamination.</p><p><strong>Results: </strong>During eyedrop administration, no videos demonstrated bottle-to-patient contact. 12/96 (12.5%) plates demonstrated growth, likely due to environmental contamination. Mass spectrometry revealed non-pathogenic and common species for 8 identifiable growths. Environmental contamination is minimized by use of a biosafety cabinet.</p><p><strong>Conclusion: </strong>We found no clinical correlation between the use of multidose eyedrop bottles and infection on multiple patients in the ophthalmology clinic. We recommend using a biosafety cabinet to establish a national consensus for multidosing eyedrops and to improve inter-study comparisons.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Denise Yang-Seeger, Yan Ning Neo, Oliver Findl, Akanksha Bagchi, Sjoerd Elferink, Johannes Birtel
{"title":"Perioperative Practice Patterns for Cataract Surgery - A Cross-Sectional European Study.","authors":"Denise Yang-Seeger, Yan Ning Neo, Oliver Findl, Akanksha Bagchi, Sjoerd Elferink, Johannes Birtel","doi":"10.1097/j.jcrs.0000000000001669","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001669","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate pre- and postoperative visits following cataract surgery in Europe and to assess the environmental impact of patient travel.</p><p><strong>Setting: </strong>High-volume cataract centers in 16 European countries.</p><p><strong>Design: </strong>A cross-sectional survey was developed and distributed by the Young Ophthalmologists for Sustainability (YOFS), a working group of the European Society of Cataract and Refractive Surgeons (ESCRS).</p><p><strong>Methods: </strong>Outcome measures included pre- and postoperative clinic visits, time and location of follow-ups, proportion of delayed and immediate sequential bilateral cataract surgery (DSBCS and ISBCS), and the option of remote follow-up visits.</p><p><strong>Results: </strong>In total, 89 responses were collected. Most departments performed 2,000 to 5,000 cataract surgeries per year. If ISBCS was offered, this accounted for less than 5% in most units. The number of preoperative visits varied between 1 (78%) and ≥3 (4%), with half of the units undertaking preoperative visits before the second eye surgery. The number of postoperative visits ranged from 1 to 4; most centers performed 1 (35%) or 2 (45%). In total, the mean number patient reviews was 5.7 (range: 3.3-9.3) for DSBCS and 3.0 (range: 2.3-4.0) for ISBCS. Remote follow-up visits were only offered by 6 centers.</p><p><strong>Conclusions: </strong>Large regional differences regarding the frequency of pre- and postoperative visits for cataract surgery were observed. Reducing the number of face-to-face visits may reduce costs for healthcare systems and patients, improve patient convenience, improve capacity, and may serve as a step towards more sustainable care by reducing travel-related carbon emissions.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giacomo Savini, Daniela Nicolosi, Kenneth J Hoffer, Catarina P Coutinho, Maria Cristina Curatolo, Domenico Schiano-Lomoriello
{"title":"Optical confirmation by a thick-lens formula of the optimized A-constant (as calculated by a thin-lens formula) of a new intraocular lens.","authors":"Giacomo Savini, Daniela Nicolosi, Kenneth J Hoffer, Catarina P Coutinho, Maria Cristina Curatolo, Domenico Schiano-Lomoriello","doi":"10.1097/j.jcrs.0000000000001671","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001671","url":null,"abstract":"<p><strong>Purpose: </strong>To provide a physical explanation for the A-constant of a new enhanced monofocal intraocular lens (IOL) by evaluating the relationship between the postoperative anterior chamber depth constant (ACD-constant) predicted by the Olsen formula, the ACD predicted by the Holladay formula and the postoperative ACD measured by anterior segment optical coherence tomography (AS-OCT).</p><p><strong>Setting: </strong>IRCCS Bietti Foundation, Rome, Italy.</p><p><strong>Design: </strong>Retrospective case series.</p><p><strong>Methods: </strong>In a series of consecutive patients that underwent cataract surgery with the same enhanced monofocal IOL, the A-constant of the SRK/T formula was optimized. The postoperative distance between the corneal epithelium and the anterior surface of the IOL was measured by AS-OCT (MS-39, CSO) and compared to the ACD predicted by the Olsen formula (PhacoOptics) and the method described by Holladay to correlate the thin-lens IOL position to the thick-lens IOL position.</p><p><strong>Results: </strong>Twenty-one eyes were investigated. The back-calculated optimized A-constant was 118.33. The mean measured IOL distance from the corneal epithelium was 4.24 ± 0.28 mm. Based on the A-constant value of 118.33, PhacoOptics calculated that the mean predicted ACD constant specific for this IOL was 4.28 mm, while the mean predicted ACD based on the individual preoperative biometric parameters was 4.17 ± 0.23 mm. According to the Holladay method, the IOL distance from the corneal vertex was 4.21 ± 0.36 mm. Repeated measures ANOVA disclosed that the difference among the 3 values was not significant (p = 0.3535).</p><p><strong>Conclusions: </strong>The optimized A-constant correlates well with the thick-lens values calculated for the postoperative ACD.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liliana Werner, Neil Kelkar, Kevin Eid, Reiker G Ricks, Emilie L Ungricht, Jeff H Pettey
{"title":"Evaluation of Corneal Endothelium Damage with a New Handheld Fragmentation Device.","authors":"Liliana Werner, Neil Kelkar, Kevin Eid, Reiker G Ricks, Emilie L Ungricht, Jeff H Pettey","doi":"10.1097/j.jcrs.0000000000001668","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001668","url":null,"abstract":"<p><strong>Purpose: </strong>To quantify damage to corneal endothelial cells (CECs) from a new handheld lens fragmentation device and compare it with damage from a standard phacoemulsification device.</p><p><strong>Setting: </strong>John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.</p><p><strong>Design: </strong>Experimental Study.</p><p><strong>Methods: </strong>Fifteen New Zealand white rabbits received bilateral surgery. Their eyes were divided into 3 groups (10 eyes/group): Intrepid Balanced Tip (Centurion Ozil handpiece; Alcon), miCOR 700 (Zeiss) half throttle (infusion/aspiration only), or full throttle (lens agitator engaged). After incision, the tip of each device was inserted into the anterior chamber and activated for 30 seconds. Following euthanasia and enucleation, the corneas were removed, stained with trypan blue/alizarin red, and photographed in a standardized manner (five X400 magnification photos from the center of each cornea). The ImageJ program was used to evaluate CEC damage and loss in the photographs.</p><p><strong>Results: </strong>The overall differences among the 3 groups regarding intact, damaged, and lost cells were statistically significant. However, by applying the Bonferroni correction, only the post-hoc pairwise comparisons between groups 1 (phaco tip) and 2 (miCOR tip, half throttle, without lens agitator engaged) were statistically significant regarding the 3 above-mentioned parameters.Conclusion: miCOR is a handheld, finger-controlled lens removal device with a blunt and rounded tip that vibrates at a low frequency, using mechanical agitation for nuclear disassembly. This acute rabbit study suggests CEC damage from the device, when the lens agitator is engaged is comparable to that of standard torsional phacoemulsification.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of two side-port incisions in phacoemulsification.","authors":"Huafang Guo, TingTing Peng, Wnjing Luo, Anqi Xie","doi":"10.1097/j.jcrs.0000000000001661","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001661","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this project is to compare the accuracy, safety, and consistency of near-square and asymmetric trapezoid side-port incisions in cataract surgery.</p><p><strong>Setting: </strong>Aier Eye Hospital of Wuhan University, Wuhan Hubei Province, China.</p><p><strong>Design: </strong>Prospective pilot study.</p><p><strong>Methods: </strong>The patients were divided into Groups A and B using the random number table method. Group A received a near-square side-port incision (SPI) with a 22G needle, and Group B received an asymmetric trapezoid SPI with a 15-degree blade. We contrasted the differences in incision length, width, and shape; surgical time; and postoperative intraocular pressure (IOP) between the two groups.</p><p><strong>Results: </strong>Eighty eyes from 80 patients were included. The mean external width of incision in Group A was much smaller than that in Group B (p < .01), while the internal width in Group A was significantly larger (p < .01). In Group A, there is no statistically significant difference between the external and internal incision diameters (p = .081). In Group B, the external diameter is obviously larger than the internal diameter (p < .01). The incision diameter consistency in Group A was higher than that in Group B. There was no statistically significant difference in incision length between the two groups (p = 0.67). One day after surgery, there were no significant differences in incision morphology (p = 1.0; .723) or operating time between the two groups (p = .89). There was no obvious incision leakage in either group after surgery (p =.337).</p><p><strong>Conclusions: </strong>The present study suggests that a near-square side-port with a 22G needle is smaller and results in better incision consistency. Moreover, the 22G needle is inexpensive and can be easily obtained.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel Spore-Like Calcification on a Hydrophilic Acrylic Intraocular Lens.","authors":"Sheng-Chu Chi, Shih-Jen Chen","doi":"10.1097/j.jcrs.0000000000001662","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001662","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jay S Pepose, Vance Thompson, Phillip Hoopes, George Waring, Ronald Luke Rebenitsch, Scott M MacRae, Kendall E Donaldson, Daniel S Durrie, Susana Marcos
{"title":"Assessing Ocular Dominance: Rethinking the Current Paradigm.","authors":"Jay S Pepose, Vance Thompson, Phillip Hoopes, George Waring, Ronald Luke Rebenitsch, Scott M MacRae, Kendall E Donaldson, Daniel S Durrie, Susana Marcos","doi":"10.1097/j.jcrs.0000000000001659","DOIUrl":"10.1097/j.jcrs.0000000000001659","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the concordance of a binary, motor sighting test of ocular dominance with a new sensory test using a simultaneous, binocular, head-mounted visual simulator to both identify and quantify the strength of eye dominance (EDS) at near and far.</p><p><strong>Setting: </strong>5 U.S. Private Practices.</p><p><strong>Design: </strong>Prospective, multicentered, double masked, non-interventional, comparative study.</p><p><strong>Methods: </strong>Prospective participants underwent sighting dominance testing using a 'hole-in-the-card' method through their distance refraction. Sensory testing was performed using a wearable, head-mounted, binocular, see-through visual simulator activating an optotunable lens on pupil conjugate plane, set to introduce monocular defocus for masked determination of both ocular preference and eye dominance strength (EDS) at far and at near (correcting the vergence with positive lenses).</p><p><strong>Results: </strong>Of 326 subjects, strong ocular dominance was found at far and at near in 50% (N=163) and 56% (N=183), respectively, with roughly equal remaining distribution between weak and equidominance. In 41% (N=134), the eye chosen to be the dominant eye with the 'hole-in-the-card' sighting method did not match the results from the sensory dominance test. In addition, in 26% (N=85), the subject changed from right eye dominance with the 'hole-in-the-card' to left eye dominance with the sensory EDS test; and 15% (N=49) changed from left to right.</p><p><strong>Conclusions: </strong>Assignment of ocular dominance with the commonly used 'hole-in-the card' test often does not align with the patient's preferred eye using sensory testing with a visual simulator simulating monovision. Further investigation will determine whether both strength and localization of ocular dominance in planning monovision are important factors in predicting patients' satisfaction and adaptation to monovision.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving refractive predictability with high-powered intraocular lenses: Refractive implications of various optic designs.","authors":"David L Cooke, Michael S Seward, Timothy L Cooke","doi":"10.1097/j.jcrs.0000000000001660","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001660","url":null,"abstract":"<p><strong>Purpose: </strong>To identify and reduce refractive prediction errors associated with several common intraocular lens (IOL) models.</p><p><strong>Setting: </strong>Multiple private and university practices across the United States.</p><p><strong>Design: </strong>Retrospective analysis of a large de-identified database.</p><p><strong>Methods: </strong>For all IOL models with at least 800 eyes, prediction errors were plotted as a function of IOL power using Olsen, Barrett, and Cooke K6 (K6) formulas. Plots were categorized as myopic, hyperopic, or neutral profiles, according to their prediction error trends at higher dioptric powers. Prediction modifications (PMODs) were developed with K6 formula, via optical calculations for one IOL (SA60AT), and by empirical data for all others. The PMODs were then tested for their applicability to other modern IOL formulas.</p><p><strong>Results: </strong>Data from 71,183 cataract surgeries were analyzed. At higher powers, Tecnis platform IOLs and one Acrysof model IOL produced unintended myopia. Conversely, enVista platform IOLs produced unintended hyperopia at higher powers. In all cases, results were improved when incorporating PMODs. In 12 of 13 cases, predictability as measured by root-mean-square error was improved (P < 0.03). This included measurements by seven modern formulas in the case of the Tecnis data. Overall, 1306 eyes (1.8%) required more than 0.25 D of adjustment to their predicted refractions. At highest available powers, the needed prediction corrections were -0.61, +0.76, and -0.69 for the Tecnis, enVista, and SN60AT IOLs, respectively.</p><p><strong>Conclusions: </strong>Above 23.5 D, some IOLs cause either myopic or hyperopic prediction errors. Specific adjustments are recommended to improve refractive predictability for several common IOL models.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Romero, Alicia Cárceles Montoya, Jorge L Alió, Alejandro Moya Martínez, Claudia Tarazona Jaimes, Jose Juan Martínez-Toldos
{"title":"Multiformula Prediction Range: a univariate predictor of IOL Power Calculation Accuracy.","authors":"Daniel Romero, Alicia Cárceles Montoya, Jorge L Alió, Alejandro Moya Martínez, Claudia Tarazona Jaimes, Jose Juan Martínez-Toldos","doi":"10.1097/j.jcrs.0000000000001658","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001658","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the influence of range between the predictions of 5 different calculation formulas in IOL power calculation accuracy.</p><p><strong>Settings: </strong>General University Hospital of Elche, Spain.</p><p><strong>Design: </strong>Retrospective Sequential Cohort.</p><p><strong>Methods: </strong>In this retrospective sequential cohort, the LenStar LS900 (Haag-Streit, Koeniz, Switzerland) was used for the preoperative biometry. The predicted spherical equivalent refraction of the implanted IOL were calculated for 5 different formulas: Barrett Universal II, Emmetropia Verifying Optical (EVO) 2.0, Hill RBF-3.0, Kane, PEARL-DGS. Multiformula Prediction Range was defined as the range of the refractive error predicted by the 5 formulas. According to the median of the Multiformula Prediction Range the sample was divided into a low and high spread group (LS and HS respectively).</p><p><strong>Results: </strong>278 eyes were included. The standard deviation of the prediction error was significantly lower in the LS group for all included formulas. For the Barrett Universal II, EVO 2.0, RBF-3.0, Kane and PEARL-DGS formulae, the median absolute error (MdAE) was significantly lower in the LS group compared to the HS group (p-values of 0.001, 0.027, 0.004, 0.028 and 0.035, respectively). The percentage of eyes within the ±0.50D PE range was significantly higher in the LS group for all five analyzed formulas.</p><p><strong>Conclusions: </strong>Multiformula Prediction Range can be a novel univariate predictor of IOL power calculation accuracy and a potential determinant for identifying patient suitable for immediate sequential cataract surgery. Accuracy was consistently higher for all five included formulas in the Low Spread group.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}