Nathan T Cannon, David L Cooke, Jascha A Wendelstein, Erik Lehman, Seth M Pantanelli
{"title":"Reply : Impact of quality indicators on variability of keratometry measurements using a SS-OCT-based optical biometer.","authors":"Nathan T Cannon, David L Cooke, Jascha A Wendelstein, Erik Lehman, Seth M Pantanelli","doi":"10.1097/j.jcrs.0000000000001667","DOIUrl":"10.1097/j.jcrs.0000000000001667","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"538"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nan-Ji Lu, Frederik Raiskup, Lutz E Pillunat, Qin-Mei Wang, Le-Le Cui, Robert Herber
{"title":"New keratoconus grading system based on OCT: threshold adjustment for SS-OCT.","authors":"Nan-Ji Lu, Frederik Raiskup, Lutz E Pillunat, Qin-Mei Wang, Le-Le Cui, Robert Herber","doi":"10.1097/j.jcrs.0000000000001640","DOIUrl":"10.1097/j.jcrs.0000000000001640","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the performance of the STEP keratoconus (KC) grading system using swept-source optical coherence tomography (SS-OCT) and to compare the relative performance of SS-OCT and spectral-domain OCT (SD-OCT) for thickness measurements.</p><p><strong>Setting: </strong>University hospitals in Germany and China.</p><p><strong>Designs: </strong>Retrospective case-control study.</p><p><strong>Methods: </strong>Rotating Scheimpflug tomography (RSC, Pentacam) and SS-OCT (ANTERION) were used to examine 152 normal and 314 KC eyes from a German cohort; the STEP system (stroma thinnest thickness [ST] and epithelium SD [EP]) was generated in SS-OCT and compared with RSC ABC system. Pentacam and SD-OCT (RTVue-XR) data from a Chinese cohort of 236 normal and 331 KC eyes were utilized to indirectly assess interdevice agreement between SS-OCT and SD-OCT using Bland-Altman plots and linear regression. Optimized thresholds for STEP \"ST\" were determined for SS-OCT.</p><p><strong>Results: </strong>In normal eyes, STEP \"ST\" agreement with RSC \"C\" was 91.45%, dropping to 28.98% in KC eyes. STEP \"EP\" showed 58.55% and 60.53% agreement with RSC \"A\" and \"B\" in normal eyes and 36.62% and 52.87% in KC eyes, respectively. SS-OCT's ST values were estimated to be higher than those of SD-OCT (estimated mean difference = 23.18 and 20.91 μm in the normal and KC eyes, respectively). An adjusted threshold of STEP ST for SS-OCT was proposed.</p><p><strong>Conclusions: </strong>SS-OCT's STEP EP aligned well with the RSC ABC system, whereas thresholds for SS-OCT's STEP ST required adjustment for more accurate clinical application. These findings highlight important considerations for thickness measurement discrepancies between SS-OCT and SD-OCT, with broader implications for future clinical practice and research.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"511-519"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Douglas D Koch, Jack T Holladay, Kristian Naeser, Adi Abulafia, Li Wang, R Doyle Stulting, Thomas Kohnen
{"title":"Standards for analyzing astigmatic outcomes: Part II: Recommended statistical methods.","authors":"Douglas D Koch, Jack T Holladay, Kristian Naeser, Adi Abulafia, Li Wang, R Doyle Stulting, Thomas Kohnen","doi":"10.1097/j.jcrs.0000000000001645","DOIUrl":"10.1097/j.jcrs.0000000000001645","url":null,"abstract":"<p><p>Surgically induced astigmatism (SIA) is the astigmatic component of the surgically induced refractive change. Vector prediction error (PE) is the key expression for evaluating refractive surgery, defined as the vector difference between the postoperatively observed refractive astigmatism and the refractive astigmatism predicted from the preoperative measurements. Astigmatic analysis of the SIA and PE includes both univariate and bivariate analyses. The magnitude of the refractive astigmatism is a predictor of visual function and a valuable component of astigmatic reporting. For vector metrics from bivariate analysis, data should be analyzed and displayed with double-angle plots. Vector calculations can be performed independent of or relative to a reference meridian or axis. Double-angle plots with convex polygons and statistical analysis for astigmatism data can be obtained easily with the wrap-up functions from the Wilcox-Holladay-Wang-Koch Statistical Software using the free software R Project for Statistical Computing or with Eyetemis software, which is also available online.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"447-455"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sheraz Daya, Erik Mertens, Francesco Carones, David Shahnazaryan
{"title":"Comment on: From the Editor: Current and future nomenclature and categorization of intraocular lenses.","authors":"Sheraz Daya, Erik Mertens, Francesco Carones, David Shahnazaryan","doi":"10.1097/j.jcrs.0000000000001697","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001697","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to Comment from Daya et al: Current and future nomenclature and categorization of intraocular lenses.","authors":"Thomas Kohnen","doi":"10.1097/j.jcrs.0000000000001696","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001696","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144159240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhu Li Yap, Ho Lucius KangHua, Karen Kate Quilat, Hla Mynt Htoon, Wesley Guang Wei Chong, Rahat Husain, Rachel Shujuan Chong, Tina Tzee-Ling Wong
{"title":"Comparison of Ziemer LDV Z8 femtosecond laser pretreatment of cataract and conventional phacoemulsification in primary angle closure disease (PACD).","authors":"Zhu Li Yap, Ho Lucius KangHua, Karen Kate Quilat, Hla Mynt Htoon, Wesley Guang Wei Chong, Rahat Husain, Rachel Shujuan Chong, Tina Tzee-Ling Wong","doi":"10.1097/j.jcrs.0000000000001691","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001691","url":null,"abstract":"<p><strong>Purpose: </strong>Determine if FLACS in PACD is safe and if predicted IOP rise would lead to long-term sequelae.</p><p><strong>Setting: </strong>Singapore National Eye Centre.</p><p><strong>Design: </strong>Prospective randomised control study.</p><p><strong>Methods: </strong>Subjects with stable PACD and pre-existing LPIs were randomised to FLACS, or conventional phacoemulsification (control). The former underwent pre-treatment using the Ziemer LDVZ8 docking system. Supine IOP was measured at 4 time-points using an applanation tonometer - prior to speculum insertion, with speculum in-situ, with suction on, and 1 minute after suction off. The control group had IOP measured at the first 2 time points. HVF and OCT RNFL measurements were performed preoperatively, 6- and 12-months post-operatively.</p><p><strong>Results: </strong>57 eyes successfully treated. In both groups, mean IOP prior to and after speculum placement was similar. In the FLACS group, mean IOP during suction was 78.67mmHg (SD 12.07) and 1 minute post release of suction was 16.92mmHg (SD 3.68). Mean preoperative VF mean deviation (MD) for both groups was similar, -5.07 ± 3.17 SD in the FLACS group and -5.68 ± 4.77 in the control group, with improvement in both at 1 year, to -4.15 ± 5.49 and -2.25 ± 6.08 respectively. In the FLACS group, the average RNFL thickness pre- and post-operatively was 73.2 ± 25.1 SD and 87.9 ± 9.9 SD. In the controls, the average RNFL thickness pre- and post-operatively was 81.9 ± 21.4 SD and 81.5 ± 20.8 SD.</p><p><strong>Conclusions: </strong>The transient increase in IOP induced by FLACS did not increase glaucomatous damage in PACD eyes after 1 year.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dr Shafi Balal, Dr Yijun Cai, Ms Lynn Kandakji, Dr Siyin Liu, Dr Pádraig J Mullholand, Mr Marcello Leucci, Dr Nikolas Pontikos, Dr Daniel Gore, Bruce Allan
{"title":"Establishing the ground truth for keratoconus progression: combining repeated measures and adapting precision limits to disease severity in tomography.","authors":"Dr Shafi Balal, Dr Yijun Cai, Ms Lynn Kandakji, Dr Siyin Liu, Dr Pádraig J Mullholand, Mr Marcello Leucci, Dr Nikolas Pontikos, Dr Daniel Gore, Bruce Allan","doi":"10.1097/j.jcrs.0000000000001692","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001692","url":null,"abstract":"<p><strong>Purpose: </strong>Keratoconus progression is defined with reference to precision limits in corneal tomography. We set out to analyse measurement precision using a contemporary tomography device (MS-39, CSO Italia, Florence, Italy) in a large sample of keratoconus patients.</p><p><strong>Setting: </strong>Moorfields Eye Hospital, London, UK.</p><p><strong>Design: </strong>Prospective and retrospective analysis of clinical data.</p><p><strong>Methods: </strong>For a range of key corneal tomographic indices, repeatability and reproducibility were compared in a prospective series of 1,248 scans (n= 208 eyes) with 2 observers each acquiring 3 scans per eye. Measurement repeatability for single measures versus the mean of 3 consecutive measures was then compared using the same dataset. 95% repeatability coefficients (RC) were mapped at each unit interval through the measurement range in a retrospective analysis of 13,734 scans (n=4,578 eyes) to adapt progression thresholds to disease severity. Finally, keratoconus classification using alternate progression definitions was compared at 1 and 2 year time points.</p><p><strong>Results: </strong>For all corneal tomographic indices examined, no significant differences were found between MS-39 measurement repeatability and reproducibility (p>0.05), repeatability was (average) 44% improved using the mean of 3 consecutive measures, and measurement repeatability deteriorated as keratoconus advanced. Progression was classified incorrectly in over 50% of cases at both time points where adaptive thresholds and repeated measures were not used.</p><p><strong>Conclusions: </strong>MS-39 measurement precision is not significantly influenced by the operator. Consecutive repeated measures and adaptive thresholds for observed change in key tomographic parameters based on device specific precision limits tailored to disease severity are necessary for accurate classification of progression.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anouar Meziane Elotmani, Anke Messerschmidt-Roth, Walter Sekundo
{"title":"Comparison of Conventional Keratometry and Total Keratometry in Untreated Myopic Eyes and Eyes After Keratorefractive Lenticule Extraction (KLEx).","authors":"Anouar Meziane Elotmani, Anke Messerschmidt-Roth, Walter Sekundo","doi":"10.1097/j.jcrs.0000000000001690","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001690","url":null,"abstract":"<p><strong>Purpose: </strong>Aim was to evaluate the differences between conventional keratometry values and Total Keratometry (TK) before and after keratorefractive lenticule extraction (KLEx). Additionally, correlations with central corneal thickness (CCT) and other variables were assessed in this study.</p><p><strong>Setting: </strong>University Eye Hospital Marburg, Germany.</p><p><strong>Design: </strong>Retrospective exploratory comparative study.</p><p><strong>Methods: </strong>K-values and TK-values of 98 eyes were measured using an IOL Master 700 before and after KLEx. Statistical analyses, including paired t-tests and Bland-Altman analyses, were performed to compare the two measurement methods. Correlations were analysed between changes in CCT, amount of laser vision correction, and differences in K- and TK-values after KLEx.</p><p><strong>Results: </strong>Significant differences between K-values and TK-values were observed both pre- and postoperatively (p<0.0001). Bland-Altman analysis demonstrated preoperatively a bias of 0.07 D (95% CI bias: 0.049 to 0.090), while postoperatively, the bias was 0.427 D (95% CI bias: -0.474 to -0.38). A strong relationship between the amount of reduction in CCT and the difference between K- and TK-values after KLEx (R2 = 0.751, p < 0.0001) was revealed. Similarly, regression analysis showed a robust association between the amount of laser vision correction and the difference between K- and TK-values after KLEx (R2 = 0.788, p < 0.0001).</p><p><strong>Conclusion: </strong>This study demonstrates that TK-values provide a more comprehensive assessment of corneal power, especially after KLEx, where changes in the posterior corneal surface become increasingly significant. The correlations suggest that patients with higher degrees of preexistent myopia or significant amount of laser ablation require special consideration in their refractive corneal assessments.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transient vitreomacular traction syndrome caused by drops to decrease presbyopia.","authors":"Jenna N Hart, John C Hart, George H H Beiko","doi":"10.1097/j.jcrs.0000000000001694","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001694","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Findings and diagnostic imaging of 28-Year Chlorpromazine induced Corneal and Lenticular Deposits.","authors":"H T Shek, Julia Yy Chan","doi":"10.1097/j.jcrs.0000000000001693","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001693","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}