Journal of cataract and refractive surgery最新文献

{"title":"Correlation with a multifocal intraocular lens of in-vitro figures of merit with clinical visual acuity.","authors":"Jérôme Loicq, Damien Gatinel, Nicolas Willet, Christophe Pagnoulle, Maxime Dietens, Sarah Trigallez","doi":"10.1097/j.jcrs.0000000000001682","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001682","url":null,"abstract":"<p><strong>Purpose: </strong>This study assesses the link between the in-vitro optical properties of the PODFGF multifocal intraocular lens (IOL) and its visual acuity clinical performance.</p><p><strong>Setting: </strong>The study was conducted at TUDelft (NL), ULiege (BE), the Rothschild Institute (FR) and BVI (BE).</p><p><strong>Design: </strong>The study analysed three powers of the PODFGF IOL. The in-vitro imaging quality was assessed using MTF frequency sweep and through-focus MTF. Multiple figures of merit, including MTF at 25-50-100 LP/mm, MTFa, and Strehl ratio, were extracted. Data acquisitions followed two ISO norms in green and white light conditions. The correlation with patients' clinical visual acuity was evaluated.</p><p><strong>Methods: </strong>The methodology had two parts: first, characterizing the in-vitro properties of the IOL lens using Figures of Merit like MTF, MTFa, and Strehl ratio, with multiple power samples (6 to 35 D). The second part analysed the visual acuity of 413 eyes implanted with FINEVISION-HP (PODFGF). Over two years, subjective refraction, UDVA, CDVA, UIVA, DCIVA, UNVA, DCNVA, defocus curve, photopic and mesopic contrast sensitivity, and rotational stability were analyzed.</p><p><strong>Results: </strong>The correlation between in vitro MTFa evaluated from the experimental data on IOLs and the clinical visual acuity performed on implanted patients leads to an accurate prediction of vision capabilities after surgery.</p><p><strong>Conclusion: </strong>Our study clinically demonstrates on a large patient cohort that MTFa complements single-frequency MTFs and establishes a mathematical link between MTF at 50 LP/mm, MTFa, and visual acuity. Additionally, it connects the two ISO model-eye standards and highlights the link between green and white light measurements in accurately predicting visual acuity.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embraced intracorneal ring segments: an unusual case in patient with keratoconus.","authors":"Gonzalo Roig-Ferreruela, Álvaro Cabezas-Vicente, Cristina Peris-Martínez","doi":"10.1097/j.jcrs.0000000000001681","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001681","url":null,"abstract":"","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous versus Non-intravenous Sedation for Cataract Surgery: A Systematic Review and Meta Analysis.","authors":"Angelica Hanna, James Jacob Armstrong, Efstathia Tsioros, Guillermo Rocha, Cindy M L Hutnik, Iqbal Ike K Ahmed","doi":"10.1097/j.jcrs.0000000000001679","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001679","url":null,"abstract":"<p><strong>Topic: </strong>This review assesses the effectiveness of intravenous sedation compared to non-intravenous sedation for routine cataract surgery.</p><p><strong>Clinical relevance: </strong>Cataract surgery is a safe and routinely performed surgery. Sedation practices vary, with centers providing either intravenous (IV), oral or no sedation for surgery. Improving sedation practices may have significant implications for patient safety, patient experience and health system efficiency.</p><p><strong>Methods: </strong>Medline, Embase, Cochrane Library, BIOSIS, Web of Science, and CINAHL were searched from inception to July 2024 for relevant articles containing original data. Randomized controlled trials that compared IV to oral or no sedation and 1) used a validated pain scale to report on pain or 2) reported on perioperative complications were included. A random effects meta-analysis was conducted. Odds ratios, standard mean differences, 95% confidence intervals (CIs), and I2 statistics were reported. The review was registered in PROSPERO (CRD42024582495) and PRISMA guidelines were followed.</p><p><strong>Results: </strong>12 randomized controlled trials including 1130 patients were included in the meta-analysis. IV sedation was associated with significantly decreased pain compared to no sedation (SMD = -0.98, 95% CI -1.68 to -0.29). Comparing IV and oral sedation, however, there was no difference in patient reported pain (SMD = -0.54, 95% CI -1.60 to 0.52). Analysis of intraoperative complications showed that there was no significant difference in complications between patients receiving IV and oral sedation (OR = 0.68, 95% CI 0.27 to 1.73).</p><p><strong>Conclusion: </strong>For routine cataract surgery, IV sedation was associated with less pain than no sedation, but oral and IV sedation provided comparable pain control. Perioperative complications occur at similar rates regardless of sedation modality. These findings may help to inform sedation practices for cataract surgery.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of visual function and patient-reported outcomes between two full range of field intraocular lenses: a randomized controlled study.","authors":"Satish S Modi, Robert P Lehmann, Bret L Fisher, Richard E Roth, Harvey Reiser","doi":"10.1097/j.jcrs.0000000000001678","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001678","url":null,"abstract":"<p><strong>Purpose: </strong>To compare visual and patient-reported outcomes in patients with cataracts bilaterally implanted with PanOptix or Synergy intraocular lenses (IOLs).</p><p><strong>Settings: </strong>5 sites in the United States.</p><p><strong>Design: </strong>Prospective, parallel-arm randomized patient- and examiner-masked clinical study.</p><p><strong>Methods: </strong>Adult cataract patients (≥22 years) were randomized (1:1) to receive bilateral PanOptix or Synergy IOL implantation. Study endpoints: Binocular uncorrected and distance-corrected VA (logMAR) at distance, intermediate (60 cm), near (40 and 33 cm); defocus curve; patient-reported visual disturbances, spectacle independence, and visual satisfaction using questionnaires at 6 months; binocular contrast sensitivity at 3 months.</p><p><strong>Results: </strong>At 6 months, PanOptix (n = 138) was non-inferior to Synergy (n = 138) IOLs for photopic binocular uncorrected and distance-corrected VA at all tested distances (P < .05). Mesopic intermediate and near VA showed a similar trend. Defocus curves showed that both IOLs provided VA of ≤0.1 logMAR from -2.50 D to +0.50 D and <0.2 logMAR at -3.00 D. A significantly lower proportion of patients with PanOptix (vs Synergy) experienced starbursts and glare (P < .05). Most patients in both groups reported never/rarely needing eyeglasses to see and high satisfaction with vision. Both IOLs provided similar binocular contrast sensitivity at 3 months under photopic and mesopic conditions.</p><p><strong>Conclusions: </strong>PanOptix IOLs provided a similar full range of vision, spectacle independence, and contrast sensitivity, but superior tolerance to glare and starbursts, compared to Synergy IOLs.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cataract Surgery Registries: History, Utility, Barriers and Future.","authors":"James Pietris, Bobak Bahrami, Ben LaHood, Michael Goggin, Weng Onn Chan","doi":"10.1097/j.jcrs.0000000000001680","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001680","url":null,"abstract":"<p><p>Cataract surgery databases have become indispensable tools in ophthalmology, providing extensive data that enhance surgical practices and patient care. This narrative review traces the development of these databases, and summarises some of the significant contributions of these databases, such as improved surgical outcomes, informed clinical guidelines, and enhanced quality assurance. There are significant barriers to establishing and maintaining cataract surgery databases, including data protection and management challenges, economic constraints, technological hurdles, and ethical considerations. These obstacles complicate efforts to ensure data accuracy, standardisation, and interoperability across diverse healthcare settings. Large language models, and artificial intelligence has potential in streamlining data collection and analysis for the future of these databases. Innovations like blockchain for data security and cloud computing for scalability are examined as solutions to current limitations. Addressing the existing challenges and leveraging technological advancements will be crucial for the continued evolution and utility of these databases, ensuring they remain pivotal in advancing cataract surgery and patient care.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Observation of Posterior Capsule Opacification in Pediatric Eyes with Marfan Syndrome after In-the-bag Intraocular Lens Implantation.","authors":"Yalei Wang, Zexu Chen, Wannan Jia, Xin Shen, Xinyao Chen, Tianhui Chen, Yang Sun, Qiuyi Huo, Yan Liu, Linghao Song, Xinyue Wang, Zhennan Zhao, Yongxiang Jiang","doi":"10.1097/j.jcrs.0000000000001677","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001677","url":null,"abstract":"<p><strong>Purpose: </strong>To identify risk factors for posterior capsule opacification (PCO) after in-the-bag intraocular lens (IOL) implantation in pediatric patients with Marfan syndrome (MFS) and ectopia lentis (EL).</p><p><strong>Setting: </strong>Eye & ENT Hospital of Fudan University, Shanghai, China.</p><p><strong>Design: </strong>Prospective cohort study.</p><p><strong>Methods: </strong>This study included children who underwent in-the-bag IOL implantation, assisted by modified capsular tension ring (MCTR) or capsular tension ring and capsular hook (CTR-CH). Primary outcome was the incidence of PCO requiring Nd:YAG capsulotomy during follow-up period. Univariate and multivariate regression analyses were performed to identify influencing factors.</p><p><strong>Results: </strong>A total of 152 pediatric patients (152 eyes) were included, with a mean age at surgery of 6.32 ± 0.27 years. The incidence of PCO was 69.08% during the mean follow-up time of 2.84 ± 0.04 years. Patients with PCO had less severe EL severity (P = 0.008), were more frequently implanted with AcrySof IQ IOLs compared to TECNIS IOL (P = 0.002), and underwent CTR-CH implantation compared to MCTR (P = 0.036). Multivariate Cox regression analysis showed that patients receiving surgery under 5 years old (HR = 1.642, P = 0.019) and using AcrySof IQ IOL (HR = 1.698, P = 0.013) developed PCO at an earlier stage.</p><p><strong>Conclusions: </strong>PCO is a common but treatable complication following in-the-bag IOL implantation in children with MFS and EL. Patients receiving lens surgery at younger age, especially under 5 years old, and those implanted with AcrySof IQ IOLs, compared to TECNIS IOLs, should be informed of higher risks of developing PCO.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative in Vivo Assessment of Intraocular Lens Calcification: Correlation Between Optical Coherence Tomography Opacity and Straylight Measurement: In Vivo Assessment of IOL Opacification using OCT.","authors":"Lars H B Mackenbrock, Grzegorz Łabuz, Nikola Henningsen, Gerd U Auffarth, Ramin Khoramnia, Timur M Yildirim","doi":"10.1097/j.jcrs.0000000000001674","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001674","url":null,"abstract":"<p><strong>Purpose: </strong>To quantitatively assess intraocular lens (IOL) calcification using anterior segment optical coherence tomography (AS-OCT) and correlate findings with straylight measurements in patients with homogenous IOL calcification.</p><p><strong>Setting: </strong>Department of Ophthalmology, Heidelberg University Hospital, Heidelberg, Germany.</p><p><strong>Design: </strong>Prospective, observational clinical study.</p><p><strong>Methods: </strong>Healthy patients with homogenous IOL calcification underwent AS-OCT imaging with the ANTERION, with IOL opacity being automatically quantified using a custom image-analysis script. Straylight was assessed using the C-Quant straylight meter. Correlation between IOL opacity and straylight was analyzed using Spearmans' rho coefficient.</p><p><strong>Results: </strong>35 eyes of 35 patients (mean age 72.9 ± 7.8 years) were included. Mean IOL opacity was 69.15 ± 13.55 pixel intensity units (PIU) and mean straylight was 2.24 ± 0.38 log(s). A statistically significant correlation was found between IOL opacity and straylight with rho = 0.494, p = 0.003. Following linear regression model was established: straylight = 0.0569 × OCT opacity [log(s)] - 1.69 with R 2 = 0.244. Of the 35 eyes, 17 underwent IOL exchange surgery, with a mean IOL opacity of 75.69 ± 7.58 PIU and mean straylight of 2.33 ± 0.30 log(s).</p><p><strong>Conclusion: </strong>AS-OCT can quantitatively assess IOL calcification in vivo, with results correlating significantly with straylight measurements. This technique may serve as a valuable diagnostic tool for evaluating IOL opacification and assist in surgical decision-making, particularly in borderline cases.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraocular lens power calculation accuracy after keratorefractive lenticule extraction with the novel ESCRS post keratorefractive surgery calculator.","authors":"Lischke Roman, Wiltfang Rainer, Bechmann Martin, Kreutzer Thomas, Priglinger Siegfried G, Dirisamer Martin, Luft Nikolaus","doi":"10.1097/j.jcrs.0000000000001673","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001673","url":null,"abstract":"<p><strong>Purpose: </strong>To compare IOL power calculation accuracy after keratorefractive lenticule extraction (KLEx) using the ESCRS online calculator versus ray tracing, the current gold standard.</p><p><strong>Setting: </strong>Multicenter study at Ludwig-Maximilians-University Eye Hospital (Munich, Germany) and SMILE Eyes Clinics (Germany, Austria).</p><p><strong>Design: </strong>Multicenter, cross-sectional study.</p><p><strong>Methods: </strong>Patients who underwent SMILE (KLEx) and subsequent cataract surgery were included. Post-hoc IOL power calculations were performed using ray tracing (Okulix) and the ESCRS calculator (Barrett True-K post-LVC, Hoffer-QST post-LVC, EVO post-LVC). Accuracy, trueness, and precision were compared descriptively.</p><p><strong>Results: </strong>Seven eyes from seven patients were analyzed. EVO post-LVC showed the lowest mean error (-0.24±0.50D), followed by ray tracing (-0.28±0.32D) and Hoffer-QST post-LVC (-0.36±0.59D). Ray tracing, EVO post-LVC and Barrett True-K post-LVC achieved 100% accuracy within ±1.00D. Ray tracing had the lowest mean absolute error (0.35D).</p><p><strong>Conclusions: </strong>Ray tracing and ESCRS post-LVC formulas improve IOL power calculations, emphasizing the need for tailored approaches in post-KLEx eyes.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conversion of disclosed lens power formula constants.","authors":"Achim Langenbucher, Peter Hoffmann, Alan Cayless, Jascha Wendelstein, Nóra Szentmáry","doi":"10.1097/j.jcrs.0000000000001676","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001676","url":null,"abstract":"<p><strong>Purpose: </strong>To present a concept for inter-converting constants of disclosed lens power formulae and to simplify these conversions to linear prediction models for clinical use.</p><p><strong>Setting: </strong>Augen- und Laserklinik Castrop-Rauxel, Germany.</p><p><strong>Design: </strong>Retrospective single centre case series.</p><p><strong>Methods: </strong>Analysis based on a dataset with biometric measurements of 19,472 eyes in a cataractous population performed with the IOLMaster 700. The formula constant conversion from formula A to B includes 2 steps: calculation of the lens power using formula A with variation of formula A constant, and back calculation of the constant for formula B for all constant values of formula A using nonlinear iterative optimization techniques to minimize the sum of squared formula B prediction error.</p><p><strong>Results: </strong>Formula conversion was calculated for the SRK/T A constant (A = 117 to 121), Hoffer Q (pACD = 4.2 to 6.8), Holladay 1 (SF 0.5 to 3.0), Haigis (a0 0.0 to 2.5 with a1/a2 = 0.4/0.1) and Castrop (C 0.15 to 0.50 with H/R = 0.0) formulae. As the conversions follow linear dependencies, linear regression models were fitted to simplify formula constant conversions in clinical routine.</p><p><strong>Conclusion: </strong>Conversions of formula constants could be used in cases where, for example, new lens models are launched with only the nominal SRK/T A constant available, or in situations where constants for some of the formulae are not available. Conversions to constant triplets for the Haigis or Castrop formula require additional nonlinear boundary conditions to take full advantage of formulae with multiple constants.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric assessment of the Chinese version of the Near Activity Visual Questionnaire in presbyopia using Rasch analysis.","authors":"Yuecheng Ren, Jiawei Li, Xinyu Jiang, Jyoti Khadka, Yiran Wang, Chenfeng Gu, Yue Wu, Qinmei Wang, Jinhai Huang, Rongrong Gao","doi":"10.1097/j.jcrs.0000000000001675","DOIUrl":"https://doi.org/10.1097/j.jcrs.0000000000001675","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the psychometric properties of the Chinese version of the Near Activity Visual Questionnaire (NAVQ).</p><p><strong>Setting: </strong>XXX.</p><p><strong>Design: </strong>Randomization single-center observational study.</p><p><strong>Methods: </strong>The original English version of the NAVQ was translated and cross-culturally adapted into Mandarin. Participants with presbyopia completed the NAVQ. Clinical data, including monocular and binocular habitual near visual acuity (HNVA), manifest refraction spherical power, cylindrical power and near addition (ADD) were collected. The NAVQ was psychometrically assessed using Rasch analysis metrics. The criterion validity was evaluated by correlating the Rasch score with clinical data.</p><p><strong>Results: </strong>One hundred and seventy-five participants with presbyopia (median age: 65 years old, female: 42.9%) were included. Rasch analysis demonstrated that the NAVQ was unidimensional, with ordered thresholds, good measurement precision (person separation measure: 2.86), and acceptable targeting (0.99 logit). The NAVQ Rasch score correlated strongly with binocular HNVA ( rs = 0.678) compared to better-eye and worse-eye VA. It also showed moderate correlations with additional power ( rs = 0.523), and the spherical equivalent for presbyopia correction in the better-eye ( rs = 0.656) and worse-eye ( rs = 0.647) (all P < 0.001).</p><p><strong>Conclusion: </strong>The Chinese version of the NAVQ demonstrated good psychometric properties and validity in a Chinese presbyopia population.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}