Journal of Cardiothoracic Surgery最新文献

{"title":"Outcomes of rescue procedures in patients undergoing unsuccessful deployment of transcatheter mitral valve replacement.","authors":"Chikashi Nakai, Junyi Liu, Mei Xing Zuo, Saeed Tarabichi, Augustin DeLago","doi":"10.1186/s13019-026-04666-w","DOIUrl":"https://doi.org/10.1186/s13019-026-04666-w","url":null,"abstract":"<p><strong>Background: </strong>Perivalvular leak (PVL), valve embolization, and migration of valve in mitral position are critical complications of transcatheter mitral valve replacement (TMVR). To date, rescue strategies, and outcomes following unsuccessful initial TMVR deployment remain poorly documented.</p><p><strong>Methods: </strong>Between March 2016 and December 2024, 86 patients with high risk of open-heart surgery underwent TMVR with a balloon expandable valve at a single institution. 19.8% (17/86) of patients experienced unsuccessful first TMVR (unsuccessful group) due to valve embolization, migration, significant PVL, or pericardial effusion, whereas 80.2% (69/86) had successful first TMVR (successful group). We evaluated postoperative outcomes comparing unsuccessful to successful groups.</p><p><strong>Results: </strong>Among 17 patients with unsuccessful first TMVR, 70.6% (12/17) underwent additional valve deployment, with successful valve-in-valve implantation in 75.0% (9/12). 17.6% (3/17) developed valve embolization in left atrium after transcatheter rescue procedures or additional valve deployment failed, subsequently 66.7% (2/3) required emergent surgical explantation of embolized valves, 33.3% (1/3) was managed medically due to prohibitive surgical risk. Surgical patients were discharged home without complications. Early mortality in unsuccessful group was 29.4% (5/17) and 13.0% (9/69) in successful group. There was no significant difference in early mortality between the 2 groups (p = 0.10). Median follow-up term was 10 months. Cumulative survival rate in 12 months was 50.5% in unsuccessful group, and 60.0% in successful group. Mid-term outcomes were similar between the 2 groups (p = 0.34).</p><p><strong>Conclusions: </strong>The study was underpowered to detect differences in all-cause mortality, but unsuccessful deployment was associated with substantially higher numerical early mortality and significantly higher cardiac mortality.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149227887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aerobic exercise modulates macrophage polarization and promotes cardiac recovery after myocardial infarction in rats.","authors":"Mingyan Zhu, Bing Zhou, Jianye Peng, Kong Chen, Yu Wang, Hao Zeng, Xia Zhang","doi":"10.1186/s13019-026-04603-x","DOIUrl":"https://doi.org/10.1186/s13019-026-04603-x","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the protective effects of aerobic exercise (AE) on cardiac function and myocardial injury in rats with myocardial infarction (MI), as well as its impact on macrophage polarization.</p><p><strong>Methods: </strong>A rat model of chronic post-infarction remodeling was established by ligation of the left anterior descending coronary artery, while the Sham group underwent threading without ligation. After a 4-week recovery period, rats in the exercise group underwent an 8-week aerobic training program, with all assessments performed at approximately 12 weeks after MI induction. The maximal aerobic velocity test was performed to assess changes in exercise endurance. To evaluate cardiac architecture, inflammatory infiltrates, and the extent of fibrosis, we performed standard histological staining with hematoxylin-eosin and Masson's trichrome. Triphenyltetrazolium chloride staining was applied to distinguish infarcted and viable myocardial regions. Commercial assay kits were used to detect myocardial injury markers, inflammatory cytokines, and oxidative stress indicators in myocardial tissue or serum. Western blotting and immunofluorescence staining were performed to assess macrophage polarization.</p><p><strong>Results: </strong>AE markedly improved cardiac function in MI rats. It also attenuated MI size and fibrosis. Serum levels of cardiac damage-associated biomarkers (cTnI, CK-MB, and LDH) were significantly decreased following AE, suggesting attenuation of ongoing myocardial injury and adverse remodeling in the chronic post-infarction setting, as were pro-inflammatory cytokines and oxidative stress indicators. Anti-inflammatory and antioxidant capacity were also enhanced by AE. M1 macrophage markers were reduced, along with upregulation of M2 macrophage markers in the myocardial tissue after AE.</p><p><strong>Conclusion: </strong>Moderate-intensity AE alleviates myocardial injury, inflammation, and oxidative stress, and promotes macrophage polarization toward the M2 phenotype in rats with MI. These findings may provide evidence for exercise-based rehabilitation and immune-targeted therapeutic strategies.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149227956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel and simple Inflation-deflation method with inflated targeted segments for confirming the intersegmental border under video-assisted thoracoscopic surgery: a technical note.","authors":"Wei Chen, Zhanwu Yu","doi":"10.1186/s13019-026-04606-8","DOIUrl":"https://doi.org/10.1186/s13019-026-04606-8","url":null,"abstract":"<p><p>With the increase in the diagnosis rate of small pulmonary nodules, the segmentectomy has been increasingly used in clinical practice worldwide. However, for the segmentectomy, the confirmation of intersegmental plane has always puzzled many thoracic surgeons. This paper described a new method, named artery-based Inflation-deflation method, used to confirm the intersegmental border under video-assisted thoracoscopic surgery. After only dividing the targeted segment artery and preserving the targeted segmental veins and bronchi, the intersegmental plane was successfully generated by this novel Inflation-deflation method. Compared with other current methods, this new technique had some advantages including the smaller airway damage, easier to determine the intersegmental plane, the higher fault-tolerant rate and easy to operate without any additional devices. And a further clinical study should be carried out to verify the feasibility and applicability of this new technique.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149227961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left ventricular myxoma diagnosed by multimodal cardiac imaging with postoperative recurrence: a case report.","authors":"Xiuling Wang, Ping Chen, Yun Mou","doi":"10.1186/s13019-026-04591-y","DOIUrl":"https://doi.org/10.1186/s13019-026-04591-y","url":null,"abstract":"<p><strong>Background: </strong>Left ventricular myxoma is a rare benign cardiac tumour. Diagnosis relies on multimodal imaging, and postoperative recurrence is uncommon.</p><p><strong>Case presentation: </strong>A middle-aged woman with a two-week history of recurrent chest tightness and dyspnoea upon exertion was admitted to our hospital. Transthoracic and transoesophageal echocardiography revealed an irregular, hypoechoic mass (approximately 61 mm × 24 mm) in the left ventricular outflow tract. The mass had a broad base attached to the inferior and posterior walls of the left ventricle, involving the posterior mitral valve leaflet, partial chordae tendineae, and papillary muscles. It exhibited significant deformation and extensive mobility during the cardiac cycle, prolapsing towards the aortic valve orifice during systole and returning to the left ventricular inflow tract during diastole. Cardiac magnetic resonance imaging revealed a mass on the inferior and posterior walls of the left ventricle that involved the posterior mitral leaflet, partial chordae tendineae, and papillary muscles. The mass showed no significant enhancement, suggesting a benign lesion, with myxoma as the primary consideration. Whole-body positron emission tomography/computed tomography revealed a slightly hypodense patchy shadow within the left ventricular cavity adjacent to the mitral valve area, accompanied by calcification and mildly increased fluorodeoxyglucose metabolism. Therefore, malignancy could not be entirely excluded. Owing to the unusual location, extensive involvement, high mobility and deformability of the mass close to the aortic orifice, and the consequent risk of embolism, surgical resection of the cardiac myxoma along with mitral valve replacement was performed. At the six-month postoperative follow-up, tumour recurrence was detected by echocardiography.</p><p><strong>Conclusions: </strong>This case highlights the importance of multimodal cardiac imaging in the diagnosis of left ventricular myxoma, with echocardiography being the most frequently utilised modality. Cardiac magnetic resonance imaging is highly specific for distinguishing between benign and malignant tumours. Echocardiography plays a critical role in the postoperative follow-up of patients with cardiac tumours.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between preoperative hydration and cardiac surgery-associated acute kidney injury: a prospective observational study.","authors":"Ghaith Mohsen, Julia Wallqvist, Zheng-Yii Lee, Anna Buckenmayer, Judith von Oppenkowski, Ajay Moza, Rachad Zayat, Daniel Catena, Lorenzo Germinarioa, Maren Kleine-Brueggeneya, Sascha Ott, Benjamin O'Brien, Markus Velten, Christian Stoppe","doi":"10.1186/s13019-026-04538-3","DOIUrl":"10.1186/s13019-026-04538-3","url":null,"abstract":"<p><strong>Background: </strong>Cardiac surgery associated acute kidney injury (CSA-AKI) is a common and serious complication following cardiac surgery with cardiopulmonary bypass (CPB), associated with prolonged hospitalization, increased costs, and higher mortality rates. Pathophysiological reasons and preventive strategies remain limited. Preoperative hydration and restriction of fluid fasting represent potentially modifiable factors, yet their association with postoperative CSA-AKI remains poorly understood.</p><p><strong>Objective: </strong>To explore the association between preoperative oral hydration and CSA-AKI in patients undergoing elective cardiac surgery with CPB.</p><p><strong>Design, setting, and participants: </strong>Prospective, single centre, observational hypothesis-generating study. Preoperative hydration surrogate was estimated based on patient self-reporting of fluid intake between admission and surgery. ROC analysis yielded a Youden Index-derived cut-off of 51.5 ml/h to stratify patients into low and high intake groups. The cut-off was derived within the study sample for exploratory stratification.</p><p><strong>Main outcomes and measures: </strong>Primary endpoint was incidence of CSA-AKI within seven postoperative days, defined according to KIDIGO creatinine criteria. Secondary endpoints included incidence of renal replacement therapy (RRT), postoperative renal function parameters, intensive care unit (ICU) and hospital length of stay (LOS), 30-day mortality, and postoperative complications. Secondary endpoints were considered exploratory.</p><p><strong>Results: </strong>Of the 92 patients analysed, 16,3% (15/92) of patients developed postoperative CSA-AKI. Using a data-derived expoloratory threshold of 51.5 ml/h, patients with lower preoperative fluid intake had a higher incidence of CSA-AKI thank patients with higher intake (33.3% [13/39]) vs. (3.8% [2/53]) (p < 0.001) respectively. RRT requirement was higher in the low-intake group (17.9% [7/39] vs. 0% [0/53]). The interval from last oral intake to induction of anaesthesia was significantly longer in the low-intake group (14.6 ± 5.1 vs. 11.5 ± 4.9, p = 0.004).</p><p><strong>Conclusions: </strong>Lower preoperative fluid intake was associated with higher observed rates of postoperative rates of CSA-AKI after applying a data-derived threshold. These exploratory data-driven findings and thresholds require prospective validation studies.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148578494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical spectrum and risk factors for severe arrhythmias in non-surgical pediatric patients: a single-center retrospective study.","authors":"Liuqing Yang, Ce Deng, Bailing Zhang","doi":"10.1186/s13019-026-04585-w","DOIUrl":"https://doi.org/10.1186/s13019-026-04585-w","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the clinical spectrum and identify risk factors for severe arrhythmias in children.</p><p><strong>Methods: </strong>A single-center retrospective study was conducted on 428 consecutive children (0-18 years) diagnosed with arrhythmia between January 2021 and October 2025. Patients were classified as having severe arrhythmia-related clinical presentation (severe group, n = 107) or non-severe presentation (non-severe group, n = 321) according to the presence of hemodynamic instability, syncope, heart failure, or malignant arrhythmia features. Clinical spectrum characteristics were collected. Univariate and multivariate logistic regression analyses were performed to identify independent risk factors for severe arrhythmias. Electrocardiographic (ECG), echocardiographic, and serological parameters were compared.</p><p><strong>Results: </strong>The severe group had higher proportions of infants/toddlers (0-3 years), underlying cardiac disease, syncope history, and class III-IV heart function (P < 0.05). Multivariate analysis identified these as independent risk factors (P < 0.05): infant/toddler age [2.30 (1.08-4.89)], underlying cardiac disease [12.66 (6.01-26.68)], syncope history [45.84 (12.74-164.91)], and class III-IV heart function [32.97 (13.39-81.17)]. The prediction model showed good fit (Hosmer-Lemeshow P = 0.171) and discrimination (AUC = 0.925, 95% CI: 0.893-0.958). The severe group also exhibited longer QTc, wider QRS, more third-degree atrioventricular block, higher ventricular premature burden, larger cardiac dimensions (LVEDD/LAD Z-score), higher pulmonary artery systolic pressure and myocardial injury/heart failure markers (CK-MB, cTnI, BNP, NT-proBNP), but lower heart rate variability (SDNN), left ventricular ejection fraction, and serum potassium (P < 0.05).</p><p><strong>Conclusion: </strong>Infant/toddler age, underlying cardiac disease, syncope history, and advanced heart failure are independent clinical risk factors for severe pediatric arrhythmias. A model incorporating these factors demonstrates strong predictive ability for early high-risk identification.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and validation of brown adipocyte-related key genes in ST-segment elevated myocardial infarction.","authors":"Hongmin Li, Xiaolin Chen, Changhui Ma, Yuanyuan Wang","doi":"10.1186/s13019-026-04649-x","DOIUrl":"10.1186/s13019-026-04649-x","url":null,"abstract":"<p><p>ST-segment elevation myocardial infarction (STEMI), a critical manifestation of coronary artery disease, involves complex molecular mechanisms potentially linked to brown adipocyte (BA) biology. This study aimed to identify BA-related key genes and elucidate their roles in STEMI progression. Transcriptomic data from peripheral blood mononuclear cells (PBMCs) of STEMI patients and stable coronary artery disease (CAD) controls were obtained from the GEO database (GSE59867, GSE62646). A 102-gene brown adipocyte-related gene (BARG) set was curated from published literature. Differentially expressed genes (DEGs) were identified using limma, and weighted gene co-expression network analysis (WGCNA) combined with single-sample gene set enrichment analysis (ssGSEA) was applied to detect BARG-associated module genes. The intersection of DEGs and module genes yielded 20 candidate genes, which were further refined using LASSO regression and SVM-RFE machine learning algorithms, identifying ASGR2, MCEMP1, and PPARG as key genes consistently upregulated in STEMI across both datasets. A nomogram model incorporating these three genes achieved an area under the ROC curve (AUC) of 0.973, demonstrating excellent diagnostic performance. Gene set enrichment analysis (GSEA) revealed convergent enrichment of all three key genes in neutrophil degranulation and Toll-like receptor signaling cascades. Immune infiltration profiling using CIBERSORT identified significant increases in monocytes alongside decreases in resting NK cells and eosinophils in STEMI, with all three key genes showing significant correlations with these immune cell populations. Molecular docking identified shinpterocarpin as a candidate compound targeting PPARG with a suggestive binding affinity (-5.8 kcal/mol), warranting further experimental validation. RT-qPCR in an independent preliminary clinical cohort (n = 5 per group) demonstrated upregulation of all three key genes in STEMI patients (p < 0.05), consistent with bioinformatic predictions. This study identifies ASGR2, MCEMP1, and PPARG as BA-associated key genes in STEMI PBMC profiles and highlights their potential immune-metabolic relevance.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13615575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149061172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of aquatic therapy in cardiovascular disease: a bibliometric analysis from 1992 to 2025.","authors":"Yang Yang, Caihong Song, Zheng Bei, Feifan Wang","doi":"10.1186/s13019-026-04622-8","DOIUrl":"https://doi.org/10.1186/s13019-026-04622-8","url":null,"abstract":"<p><strong>Background: </strong>Aquatic therapy has emerged as a promising approach for cardiovascular diseases (CVD). To evaluate trends and hotspots in this area, a bibliometric analysis was conducted from 1992 to 2025.</p><p><strong>Methods: </strong>A systematic search was conducted on the Web of Science Core Collection database (SCIE and SSCI) to identify publications on aquatic therapy in CVD from 1992 to 2025. A disease-specific search strategy using validated CVD terminology was employed, followed by manual relevance screening to ensure corpus specificity. Bibliometric analysis used VOSviewer (v1.6.20), CiteSpace (v6.3.R1) and R package \"Bibliometrix\" (V4.5.2).</p><p><strong>Results: </strong>The analysis included 94 articles by 473 authors from 321 institutions across 34 countries. The annual publication growth rate was 6.07%. Brazil, China, and Sweden were the most productive countries. Universidade de São Paulo published the most articles. High-impact journals such as International Journal of Biometeorology and European Journal of Heart Failure were key in disseminating research. Authors Guimarães Guilherme Veiga and Bocchi Edimar Alcides emerged as central figures in collaboration networks. Keyword analysis identified six thematic clusters: (1) hemodynamic responses and exercise protocols; (2) cardiac rehabilitation, vascular function, and clinical outcomes; (3) CVD risk management and clinical guidelines; (4) exercise prescription, quality of life, and program design; (5) balneotherapy, blood pressure control, and comorbid conditions; and (6) aquatic exercise, physical activity, and population-specific interventions. Research evolved from physiological responses and protocol development to quality of life, patient-centered outcomes, and clinical implementation. Burst analysis showed \"cardiac rehabilitation,\" \"endothelial function,\" and \"physical activity\" as prominent research frontiers since 2018.</p><p><strong>Conclusion: </strong>This bibliometric analysis provides an overview of research in aquatic therapies for CVD. The field has evolved from early physiological investigations toward clinical applications within cardiac rehabilitation frameworks. Future research trends are expected to focus on the integration of aquatic therapy into evidence-based cardiac rehabilitation programs, long-term outcome evaluation, and patients' quality of life.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy and safety of immunotherapy after concurrent chemoradiotherapy in advanced esophageal cancer.","authors":"Chunxiu Hu, Yi Liu, Zhengqi Yang, Qin Chen, Yuefang Tong, Bin Da, Yuefei Sun, Huiting Rao","doi":"10.1186/s13019-026-04502-1","DOIUrl":"10.1186/s13019-026-04502-1","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the efficacy and feasibility of PD-1 antibody combined with concurrent chemoradiotherapy in patients with esophageal cancer.</p><p><strong>Methods: </strong>From July 2020 to October 2023, 15 patients with esophageal cancer in Zhejiang Quhua Hospital were treated with PD-1 monoclonal antibody after concurrent chemoradiotherapy. The incidence of adverse reactions was recorded throughout the treatment period. The Kaplan-Meier survival analysis was used to estimate median overall survival (OS) and progression-free survival (PFS).</p><p><strong>Results: </strong>All 15 patients were enrolled, with a median follow-up of 23.0 months (ranging from 6.0 to 37.5 months). The 1-year OS rate was 93.3%, and the 2-year OS rate was 46.7%. No treatment-related deaths were reported.</p><p><strong>Conclusion: </strong>Concurrent chemoradiotherapy combined with PD-1 antibody yielded encouraging survival outcomes in patients with esophageal cancer, and this regimen deserves further clinical exploration.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a voice-guided tap-and-talk educational tool in enhancing cardiovascular knowledge and self-management in aged patients following percutaneous coronary intervention.","authors":"Tingting Sun, Lili Liu, Rui Ye, Yaqi Wei, Xia Li","doi":"10.1186/s13019-026-04546-3","DOIUrl":"10.1186/s13019-026-04546-3","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to develop a voice-guided, tap-and-talk educational tool and assess its effectiveness in improving disease-related knowledge and self-management behaviors among older adults following percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>A voice-guided tap-and-talk educational tool was designed to address the specific needs of older adults post-PCI. A cluster randomized controlled trial was conducted in cardiovascular wards. The control group received conventional health education using printed manuals, whereas the intervention group received education via the tap-and-talk interactive tool. Outcomes included the level of knowledge regarding coronary heart disease and engagement in self-management behaviors. Chi-squared test and independent-sample t-test, chi-square test and paired t-test, and univariate repeated-measures analysis of variance (ANOVA) were conducted accordingly.</p><p><strong>Results: </strong>A total of 96 patients completed the study, including 49 in the experimental group and 47 in the control group.No statistically significant differences were observed in baseline characteristics between the groups (p > 0.05). A significant group × time interaction effect was detected for coronary heart disease (CHD)-related knowledge (F = 9.026, P < 0.001). At 1 month, 3 months, and 6 months post-intervention, the intervention group demonstrated significantly higher self-management behavior scores than the control group (F = 11.607, P < 0.001). Additionally, CHD-related knowledge scores showed a mild downward trend over time in both groups (F = 124.067, P < 0.001). Consistent with the interaction effect mentioned above, the intervention group achieved significantly higher CHD-related knowledge scores than the control group at all three follow-up time points (1 month, 3 months, and 6 months post-intervention) (F = 195.188, P < 0.001). Scores in the intervention group remained consistently higher across all domains. The tool received high acceptance ratings from participants (mean score 96.04 ± 2.61).</p><p><strong>Conclusion: </strong>The tap-and-talk voice-guided educational tool was effective in enhancing knowledge and promoting self-management behaviors among older adults following PCI. The tool demonstrated a high level of user acceptability within the target population.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"21 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}