Journal of Cardiothoracic Surgery最新文献

{"title":"Radiological challenges in differentiating Occult Traumatic Pulmonary Hematoma from mediastinal tumor: a case report and literature review.","authors":"Zhedong Zhang, Yu Huang, Lufeng Zhao, Baiqin Zhao","doi":"10.1186/s13019-024-03243-3","DOIUrl":"10.1186/s13019-024-03243-3","url":null,"abstract":"<p><p>Traumatic Pulmonary Hematoma (TPH) is a rare consequence of blunt chest trauma, characterised by lung parenchyma laceration and subsequent hemorrhage. While less common than pulmonary contusions, TPH presents significant diagnostic challenges, particularly when it manifests as Occult Traumatic Pulmonary Hematoma (OTPH) exhibiting subtle or atypical imaging features. We report a case where OTPH was initially misdiagnosed as a posterior mediastinal tumor. A 36-year-old male with a history of minor left chest trauma presented with two oval masses in the right paravertebral region on chest computed tomography (CT). These masses were initially suspected to be mediastinal tumors.Thoracoscopic surgery revealed these lesions to be subpleural tumors in the right lower lobe, which were ultimately diagnosed as pulmonary hematomas (PH). This case highlights the necessity of including PH in the differential diagnosis of intrathoracic masses, especially when imaging findings are ambiguous. Accurate diagnosis often necessitates the integration of clinical history with advanced imaging modalities.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"111"},"PeriodicalIF":1.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dexmedetomidine for delirium prevention in adult patients following cardiac surgery: a meta-analysis of randomized controlled trials.","authors":"Chang Meng, Duo Wang, Yue Zhao, Jing Sun, Guobin Miao, Lijuan Chen, Ying Bai, Peng Liu","doi":"10.1186/s13019-025-03360-7","DOIUrl":"10.1186/s13019-025-03360-7","url":null,"abstract":"<p><strong>Objectives: </strong>To determine whether perioperative administration of dexmedetomidine reduces the incidence of postoperative delirium in adult patients undergoing cardiac surgery.</p><p><strong>Methods: </strong>We searched the PubMed, Embase and Cochrane Library databases for randomized controlled trials from the last 10 years up to March 10, 2024. We then conducted a meta-analysis to evaluate the effectiveness and safety of dexmedetomidine in preventing delirium after cardiac surgery in adults. This meta-analysis followed the steps in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA2020) guidelines. This study is registered with INPLASY under number INPLASY202430132.</p><p><strong>Results: </strong>A total of 2689 patients were included in our analyses. All included studies were randomized controlled trials. Dexmedetomidine can reduce the occurrence of delirium in patients after cardiac surgery(OR 0.75, 95%CI 0.57-0.98, I² = 12%, P = 0.04). In terms of other end events, length of intensive care unit(ICU) stay(MD -0.16, 95%CI -1.85-1.53, I² = 0%, P = 0.85) and mortality(OR 1.59, 95%CI 0.74-3.42, I² = 0%, P = 0.23) were not statistically different with dexmedetomidine compared with placebo. Bradycardia (OR 0.85, 95%CI 0.54 ~ 1.34, I² = 72%, P = 0.49) and hypotension (OR 1.97, 95%CI 0.96 ~ 4.03, I² = 84%, P = 0.06) were not significantly different between the two groups.</p><p><strong>Conclusions: </strong>Dexmedetomidine is safe for cardiac surgery patients and to some extent reduces the incidence of delirium in cardiac surgery patients, which is more important in preoperative use.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"110"},"PeriodicalIF":1.5,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies.","authors":"Moiud Mohyeldin, Sarah J Norman, Ayzia Carney, Courtney Odza","doi":"10.1186/s13019-025-03358-1","DOIUrl":"10.1186/s13019-025-03358-1","url":null,"abstract":"<p><p>Myocardial Injury after Noncardiac Surgery (MINS) is an increasingly recognized complication that significantly impacts postoperative morbidity and mortality. Characterized by elevated cardiac troponin levels without overt ischemic symptoms, MINS presents a challenge in perioperative care. This review article explores the epidemiology, etiology, and management of MINS, with a particular focus on prevention and the latest management strategies. We discuss the role of aspirin, statins, anticoagulation, and Dual Antiplatelet Therapy (DAPT) within the context of MINS, drawing on evidence from notable clinical trials as well as observational studies. Despite advancements in understanding and managing MINS, the condition continues to be associated with high mortality and major adverse cardiovascular events (MACE), underscoring the need for ongoing research and development of more effective management protocols.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"108"},"PeriodicalIF":1.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting the prolongation of mechanical ventilation in patients after cardiac surgery.","authors":"Mahdieh Sharifzadeh Kermani, Tania Dehesh, Shiva Pouradeli, Bahareh Soltani Esmaili","doi":"10.1186/s13019-024-03247-z","DOIUrl":"10.1186/s13019-024-03247-z","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the major predictive factors associated with prolonged mechanical ventilation(PMV) following cardiac surgery.</p><p><strong>Methods: </strong>This retrospective, cross-sectional, descriptive-analytical study was conducted from September 2021 to March 2022, involving 244 patients who underwent cardiac surgery. PMV was defined as mechanical ventilation for more than 24 h. Potential risk factors before, during, and after surgery were examined and recorded. Logistic regression analysis was performed to assess the relationship between demographic, clinical variables, and prolonged mechanical ventilation. A significance level of 0.05 was used for data analysis.</p><p><strong>Results: </strong>The study population consisted of 68.4% male and 31.6% female patients, with 86.9% undergoing CABG surgery. PMV was observed in 13.1% of the patients. The findings revealed that the incidence of postoperative pneumonia increased the likelihood of PMV by more than 7 times [OR = 7.24, 95% CI=(5.12,8.14), P-value = 0.001]. Similarly, respiratory failure was associated with a 7.5-fold increase in the odds of PMV [OR = 7.56, 95% CI=(4.48,8.77), P-value = 0.042]. Drainage of one liter of blood on the first postoperative day increased the risk of PMV by 2.2 times [OR = 2.21, 95% CI=(1.98,2.46), P-value = 0.032], and the use of epinephrine was associated with a 2.73-fold increase in the odds [OR = 2.73, 95% CI=(2.24,3.11), P-value = 0.022]. Risk of PMV in the patients who had cardiac dysfunctin increased by more than 2 times.[OR = 2.58, 95%; CI = (1.33.2.87); P-value = 0.042]. In the patients need an Intra Aortic Balloon Pump(IABP) risk of PMV increased by more than 2 times. (OR = 2.74,95%,CI = 1.36,5.47: Pvalue = 0.03). The risk of PMV in the patients who had cerebrovascular accident(CVA) increased by more than three times [OR = 3.75, 95% CI = 1.26,4.84; P-value = 0.044]. For each unit increase in Euro Score 2 the chance of PMV increased by 1.38 TIMES. Furthermore ICU Mortality had a significant relationship with PMV.(Pvalue < 0.001).</p><p><strong>Conclusion: </strong>The study identified postoperative complications, such as pneumonia, respiratory failure, high drainage, need to an IABP, higher EURO Score 2, Cardiac dysfunction, CVA and the use of epinephrine, as independent risk factors for PMV following cardiac surgery.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"104"},"PeriodicalIF":1.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of stroke associated with proton pump inhibitor use among individuals with and without pre-existing cardiovascular diseases: a systematic review and meta-analysis.","authors":"Muhammed Shabil, Bijaya K Padhi, Mahalaqua Nazli Khatib, Soumya V Menon, Mandeep Kaur, Mukesh Kumari, Puneet Sudan, K Satyam Naidu, Quazi Syed Zahiruddin, Sarvesh Rustagi, Divya Sharma, Mithhil Arora, Rakesh Kumar Sharma, Edward Mawejje, Prakasini Satapathy, Sanjit Sah","doi":"10.1186/s13019-024-03161-4","DOIUrl":"10.1186/s13019-024-03161-4","url":null,"abstract":"<p><strong>Background: </strong>Proton pump inhibitors (PPIs) are commonly used for managing gastroesophageal disorders but concerns about their potential association with increased stroke risk have emerged, especially among patients with pre-existing cardiovascular conditions such as acute coronary syndrome (ACS). This systematic review and meta-analysis aim to assess the risk of stroke associated with PPI use, stratified by the presence or absence of pre-existing CVD.</p><p><strong>Methods: </strong>This review was conducted following the PRISMA guidelines and included studies up to March 2024 from PubMed, Embase, and Web of Science. Eligible studies were longitudinal, including prospective cohorts, nested case-controls, and post-hoc analyses of RCTs that reported stroke outcomes in relation to PPI use. Data were synthesized using random-effects meta-analysis models in R software version 4.3.</p><p><strong>Results: </strong>Our search yielded 41 studies encompassing over 800,000 participants globally. Meta-analysis of 14 observational studies revealed a slight but non-significant increased stroke risk among patients with prior CVD (pooled HR = 1.222, 95% CI: 0.963 to 1.481, I² = 78%). In contrast, analysis of 15 studies without prior CVD showed a modestly increased risk (pooled HR = 1.15, 95% CI: 1.023 to 1.288, I² = 98%). Five RCTs involving patients with CVD reported a pooled RR of 1.158 (95% CI: 0.914 to 1.466), indicating no significant risk increase.</p><p><strong>Conclusion: </strong>The association between PPI use and stroke risk appears modest and is influenced by the presence of cardiovascular conditions. Clinical decision-making should consider individual patient risk profiles, and further high-quality studies are needed to guide safer PPI prescribing practices.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"107"},"PeriodicalIF":1.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lobar lung transplantation, followed by partial sternal resection and bronchial stenosis, in a patient with scoliosis.","authors":"Monika Svorcova, Jiri Vachtenheim, Jan Simonek, Jaromir Vajter, Zuzana Prikrylova, Jan Kolarik, Jiri Pozniak, Jan Havlin, Robert Lischke","doi":"10.1186/s13019-025-03345-6","DOIUrl":"10.1186/s13019-025-03345-6","url":null,"abstract":"<p><p>Scoliotic deformity represents a serious spinal disorder that influences the locomotive and cardiopulmonary systems. Some patients with severe scoliosis and end-stage lung disease are therefore denied lung transplantation. In patients with scoliosis considering lung transplantation, size match, straight back syndrome, delayed chest closure and bronchial stenosis are key issues clinicians should evaluate. Therefore, it is vital to determine donor-recipient size matches very precisely. Chest opening is a routine intraoperative primary therapeutic procedure after lung transplantation in unstable patients with oversized transplanted lungs. Postoperative bronchial stenosis occurs predominantly on the right side and is usually handled through interventional bronchoscopy and the insertion of stents. This report describes the complex case of a patient with scoliosis who underwent lobar transplantation in our center.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"103"},"PeriodicalIF":1.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy-related chronic type A aortic dissection highlights the importance of thorough prenatal maternal examination.","authors":"Cristina M Șulea, Anna B Kiss, Bence Ágg, Kálmán Benke, Elektra Bartha, Bálint Szilveszter, Roland Stengl, Máté Csonka, Zoltán Szabolcs, Miklós Pólos","doi":"10.1186/s13019-025-03357-2","DOIUrl":"10.1186/s13019-025-03357-2","url":null,"abstract":"<p><strong>Background: </strong>Aortic dissection occurs rarely during pregnancy but carries a significantly high vital risk for both the mother and the fetus. Early diagnosis and treatment are critical for a successful outcome.</p><p><strong>Case presentation: </strong>A 32-year-old pregnant woman at 31 weeks of gestation began experiencing shortness of breath, chest pain, and palpitations, which were attributed to an anxiety disorder she had been previously diagnosed with. The symptoms continued to worsen following the delivery when a chest computed tomography investigation revealed signs of chronic type A aortic dissection and an 80 mm post-dissection aneurysm of the ascending aorta. Aortic repair via composite aortic root replacement surgery (Bentall procedure) and partial aortic arch replacement was performed. The patient's postoperative evolution was notable for a series of complications.</p><p><strong>Conclusions: </strong>Our report highlights the importance of thorough maternal examination during pregnancy. The high mortality rates associated with aortic dissection occurring in pregnant women and the possibility of missed intervention due to atypical clinical presentation warrant the need for standardized international protocols aimed at the prevention and timely diagnosis of prenatal aortic disease.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"105"},"PeriodicalIF":1.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Superior vena cava obstruction following pericardial effusion absorption in the presence of a pericardial teratoma: a case report.","authors":"Kai Guo, Hui Wang","doi":"10.1186/s13019-024-03262-0","DOIUrl":"10.1186/s13019-024-03262-0","url":null,"abstract":"<p><p>Intrapericardial teratoma is a rare tumor that usually presents in neonates or during infancy because of the associated high degree of pericardial effusion, cardiac compression and severe respiratory distress. In this paper, we report a rare case of intrapericardial teratoma that was incidentally discovered in an infant with superior vena cava obstruction following pericardial effusion absorption. Echocardiography and thoracic computed tomography angiography revealed that the intrapericardial mass obviously suppressed the superior vena cava. The tumor was resected surgically. Histopathological examination confirmed the diagnosis of mature teratoma.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"102"},"PeriodicalIF":1.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catlet scoring system as a new predictor for in-stent restenosis in patients with chronic coronary artery disease undergoing percutaneous coronary intervention with drug-eluting stent.","authors":"Juan Wang, Mingchao Zhang, Weipeng Gan, Mingxing Xu, JiaYan Zhou, Lingfei Yang, Yongsheng Ke","doi":"10.1186/s13019-025-03349-2","DOIUrl":"10.1186/s13019-025-03349-2","url":null,"abstract":"<p><strong>Background: </strong>He's team have recently developed a new Coronary Artery Tree description and Lesion EvaluaTion (CatLet) angiographic scoring system, which is capable of accounting for the variability in coronary anatomy, and risk-stratifying patients with coronary artery disease. Preliminary studies have demonstrated its superiority over the the Synergy between percutaneous coronary intervention with Taxus and Cardiac Surgery (SYNTAX) score with respect to outcome predictions for acute myocardial infarction (AMI) patients. However, there are fewer studies on the prognostic in chronic coronary artery disease(CAD). This study aimed to clarify whether the CatLet score had a predictive value for in-stent restenosis(ISR) in patients with chronic coronary artery disease undergoing percutaneous coronary intervention with drug-eluting stent(DES).</p><p><strong>Methods: </strong>A total of 260 patients who were diagnosed with chronic CAD and underwent coronary DES implantation at the second affiliated Hospital of Wannan medical college in China were consecutively enrolled from January 2020 to June 2021.Finally, 164 patients underwent the second angiography after 2 years.According to whether ISR was detected at follow-up angiography, patients were divided into the ISR group (n = 26) and the non-ISR group (n = 139).</p><p><strong>Results: </strong>A total of 165 patients (46 women and 119 men) with a mean ages of 66.19 ± 10.54 years were finally enrolled in this study. Of these, ISR occurred in 26/165 chronic CAD patients (15.76%) by follow-up angiography. Univariate analysis showed that most baseline characteristics of the ISR and non-ISR group were similar. Patients in the ISR group had significantly the history of chronic obstructive pulmonary disease(COPD), adverse lesion characteristic, higher Catlet score compared with patients in the non-ISR group.The CatLet score was capable of predicting in-stent restenosis after adjustment for risk factors; The Multivariable-adjusted model showed good calibration and good discrimination (area under ROC curve = 0.7164) for ISR.</p><p><strong>Conclude: </strong>CatLet score is a new predictor of ISR in patients with chronic CAD after coronary DES implantation.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"106"},"PeriodicalIF":1.5,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management and outcomes of thoracic sarcomas - a collaboration between Orthopaedic Oncology and cardiothoracic surgery: seven-year clinical data from a tertiary referral centre.","authors":"Zaid Ahmed Shamsi, Vlad Paraoan, Chang Kim, Sarah Raihanah Saifuddin, Thomas D A Cosker, Duncan Whitwell, Christopher L M H Gibbons, Dionisios Stavroulias, Francesco DiChiara","doi":"10.1186/s13019-025-03341-w","DOIUrl":"10.1186/s13019-025-03341-w","url":null,"abstract":"<p><strong>Introduction: </strong>Sarcomas are rare cancers originating from mesenchymal tissues, manifesting in diverse anatomical locations, but notably in connective tissue, muscles and the skeleton. Thoracic sarcomas present a unique diagnostic and surgical challenge attributable to their rarity and pathoanatomy. Standard practice currently comprises wide surgical excision, often accompanied by adjuvant chemotherapy and/or radiotherapy. This approach necessitates a multidisciplinary team, ideally in specialised cancer centres. The Oxford Bone and Soft Tissue Tumour Service is one such centre, and routinely treats such cancers through collaboration between orthopaedic oncology and cardiothoracic surgeons, as well as members of the wider MDT. This study reports the current management and outcomes of primary thoracic sarcoma patients at the Oxford Sarcoma Service over a seven-year period.</p><p><strong>Objectives: </strong>Given the rarity of thoracic sarcomas, and their associated diagnostic and management complexities, our aim is to report on the treatment strategies and outcomes of primary thoracic sarcoma patients treated at the Oxford Sarcoma Service from 2017 to 2023.</p><p><strong>Methods: </strong>Data pertaining to all thoracic sarcoma cases discussed in multidisciplinary meetings at the Oxford tertiary centre from 2017 to 2023 were retrieved from the local electronic database. These were analysed using appropriate statistical tests to determine significance of the various observations made.</p><p><strong>Results: </strong>Of 113 identified cases, chondrosarcoma emerged as the most prevalent histological subtype among 22 distinct varieties. 58% of cases exhibited high-grade features. 32 sarcoma-related deaths occurred, with a mean time from diagnosis to death of 23.16 months. A notable association was observed between high-grade sarcomas and mortality (p = 0.0280). Surgical resection was performed in 77 cases, with 49% of these undergoing surgical resection alone i.e. the patient received no radio- or chemotherapy. Both surgical intervention (p < 0.0001) and clear margins (p = 0.0051) were significantly linked to improved survival. Local recurrence was noted in 28.6% of the 77 surgical cases, and predominantly in the high-grade sarcomas (81.8%). However, no statistical association was found between recurrence and margin status in our data.</p><p><strong>Conclusion: </strong>Our results indicate that primary resection remains the cornerstone of thoracic sarcoma treatment, representing the single strongest independent factor for survival in treatable cases. Variability in outcomes and overall survival likely stems from factors such as histological diversity, predominance of high-grade sarcomas, and wide age range at diagnosis. Ongoing prospective database update and collaborative efforts across centres would further clarify prognoses and recommendations for specific tumours, based on observational data.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"98"},"PeriodicalIF":1.5,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}