Journal of Cardiothoracic Surgery最新文献

{"title":"Esophageal reconstruction using a hypopharyngeal anastomosis - a single center experience with review of the literature.","authors":"Lauren Bougioukas, Lucio M Pereira, Matthew J Weiss, Lawrence R Glassman, David Zeltsman, Kevin M Hyman, Julissa E Jurado, Paul C Lee","doi":"10.1186/s13019-025-03575-8","DOIUrl":"10.1186/s13019-025-03575-8","url":null,"abstract":"<p><strong>Background: </strong>Lye ingestion or other esophageal trauma may require surgical reconstruction. The hypopharyngeal anastomosis during esophageal reconstruction is a technically demanding procedure with many nuances in approach. Patients often have a challenging post-operative course, and few regain the ability to tolerate a normal diet.</p><p><strong>Case presentation: </strong>We describe a case series of three patients (2 colon interpositions and 1 gastric pull-up) who underwent esophageal reconstruction with a hypopharyngeal anastomosis at our institution from years 2017 to 2024, then review the literature.</p><p><strong>Conclusions: </strong>We recommend a multidisciplinary team approach with otolaryngology and/or general surgery for the neck dissection and preparation of the conduit. For the hypopharyngeal anastomosis, we recommend a two-layer, interrupted suture method to the left, lateral piriform sinus along with careful laryngeal nerve preservation. Patients require close follow-up for endoscopic therapy to treat the often-inevitable dysphagia after surgery. All three patients survived and had improved swallow function after surgery.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"345"},"PeriodicalIF":1.5,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144955401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of laryngeal mask airway ventilation in selected pediatric pulmonary artery sling surgeries: a retrospective review.","authors":"Xiao Shen, Fan Zhang, HuiFeng Zhang, Ming Ye","doi":"10.1186/s13019-025-03550-3","DOIUrl":"https://doi.org/10.1186/s13019-025-03550-3","url":null,"abstract":"","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"344"},"PeriodicalIF":1.5,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12374344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144955420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Valve-Sparing Repair Improve Outcomes in Tetralogy of Fallot? A Systematic Review.","authors":"Jabez David John, Tirath Patel, Monica Kharat, Jeet HansalKumar Patel, Jubran Al Hooti, Zoya Riyaz Syeda, Rohit Anil Khare, Sonya Bhatia, Amin Ibrahim, Arjun Bellamkonda, Nikhilesh Anand, Bharathi S Gadad","doi":"10.1186/s13019-025-03519-2","DOIUrl":"https://doi.org/10.1186/s13019-025-03519-2","url":null,"abstract":"<p><strong>Background: </strong>The systematic review determines whether valve-sparing surgeries improve patient outcomes compared with non valve-sparing surgeries for tetralogy of Fallot. Although previous studies have reported superior outcomes in valve-sparing surgery, no systematic review has compared these outcomes with those of nonsurgical surgical methods.</p><p><strong>Methods: </strong>In the present research, we address this gap in the literature by comparing valve-sparing and non valve-sparing surgery outcomes. PubMed, PubMed Central, and Medline served as the databases for data collection; following the PRISMA guidelines, a comprehensive search strategy identified relevant articles for the review; the search strategy included Medical Subject heading (MeSH) terms and important keywords. The search strategy initially revealed seventy articles; these were further screened by title and abstract and refined to fifteen articles for full-text analysis. For further full-paper analysis, eight articles were refined and formed the basis of our analysis. There was a severe limitation of high-quality clinical trials and prospective studies, and we included any good-quality papers that passed the quality check and adhered to the inclusion and exclusion criteria.</p><p><strong>Results: </strong>The number of patients included in this study was 962 from 8 studies; 351 underwent valve-sparing surgery, and 611 underwent TOF correction via non valve-sparing methods. This systematic review provides encouraging evidence that suggests better outcomes for valve-sparing surgery. Most studies have consistently reported a significantly lower prevalence of moderate or severe pulmonary regurgitation in valve-sparing surgeries. Since the valve-sparing technique allows for the preservation of the native valves, it allows for better growth of the pulmonary valve. Additionally, most studies reported that valve-sparing surgeries significantly improved proper ventricular function, but mixed results regarding reintervention have been reported. The risk of complications was similar between the surgical modalities; valve-sparing repair has consistently outperformed other surgical modalities. Low birth weight remains a prominent risk factor even for valve-sparing surgery.</p><p><strong>Conclusion: </strong>In summary, the evidence presented in this review strongly supports the use of valve-sparing surgery for improved patient outcomes. This systematic review highlights the benefits of valve-sparing surgery over other surgical techniques. It can be a foundation for clinical practice that allows surgeons to make better, informed decisions about patient care. The limitations of the lack of studies found when this review was conducted can further guide other research, strengthen the evidence, and lead to better patient care.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"343"},"PeriodicalIF":1.5,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12369264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144955443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From support to recovery: the evolving role of LVAD in reversing heart failure.","authors":"Bingqi Sun, Zhigang Liu","doi":"10.1186/s13019-025-03560-1","DOIUrl":"10.1186/s13019-025-03560-1","url":null,"abstract":"<p><p>In recent years, the use of Left Ventricular Assist Devices (LVAD) in the treatment of heart failure has been increasingly widespread. Not only do they provide circulatory support for patients, but the reverse biological changes in myocardial tissue induced by LVAD have led to the recovery of heart function in some patients, allowing for the removal of the device-which termed bridge to recovery (BTR). Despite promising prospective studies reporting LVAD explantation rates exceeding 48-60% in BTR-focused cohorts, real-world registries (e.g., INTERMACS) demonstrate explantation rates below 5%, underscoring critical gaps in patient selection, standardized assessment protocols, and integration of optimized pharmacological and mechanical unloading strategies. This review synthesizes contemporary clinical and molecular insights into LVAD-mediated myocardial recovery. Clinically, key determinants of successful BTR include stringent hemodynamic and echocardiographic criteria for explantation (e.g., LVEF > 45%, PCWP ≤ 15 mmHg), and aggressive guideline-directed medical therapy (GDMT), particularly neurohormonal blockade. Mechanistically, LVAD unloading promotes reverse remodeling through metabolic reprogramming (e.g., enhanced pyruvate-lactate axis activity), restoration of calcium homeostasis, extracellular matrix modulation, and immune-mediated pathways. However, challenges persist, including the lack of predictive biomarkers, suboptimal GDMT adherence, and unresolved debates regarding concomitant cardiac procedures. Emerging evidence highlights the potential of novel pharmacotherapies (e.g., SGLT2 inhibitors, vericiguat) and individualized pump-speed algorithms to augment recovery. Pediatric populations exhibit unique recovery dynamics, with myocarditis and smaller body surface area correlating with higher explantation success. Partial cardiac recovery, observed in over 30% of LVAD recipients, warrants tailored therapeutic strategies to transition to full recovery. Future directions demand multicenter registries integrating molecular profiling with clinical outcomes, standardized BTR protocols, and exploration of adjuvant therapies. By redefining BTR as an achievable goal rather than a rare exception, this paradigm shift could transform advanced heart failure management, offering patients liberation from lifelong device dependency.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"340"},"PeriodicalIF":1.5,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12363120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra-aortic balloon pump can be used after acute type A aortic dissection repair.","authors":"Akiko Tanaka, Yuki Ikeno, Harleen K Sandhu, Charles C Miller Iii, Hazim J Safi, Anthony L Estrera","doi":"10.1186/s13019-025-03556-x","DOIUrl":"10.1186/s13019-025-03556-x","url":null,"abstract":"<p><strong>Objectives: </strong>We analyzed our data to evaluate the safety and feasibility of intraoperative extracorporeal membrane oxygenation and intra-aortic balloon pump use in acute type A aortic dissection repair.</p><p><strong>Methods: </strong>Between December 1999-December 2020, we identified patients who received intraoperative extracorporeal membrane oxygenation and/or intra-aortic balloon pump support to wean off cardiopulmonary bypass were retrospectively reviewed.</p><p><strong>Results: </strong>A total of 690 patients who underwent acute type A dissection repair. In all, 31 patients received intraoperative circulatory support (11 extracorporeal membrane oxygenation, 20 intra-aortic balloon pump) to wean off cardiopulmonary bypass. In all, 14 patients (45%) were female and the median age was 65 years (interquartile range 51-73). Prior to the acute type A dissection repair, 13 (42%) had coronary malperfusion, 7 (23%) had visceral malperfusion, 4 (13%) presented with acute coronary syndrome, and 8 (26%) received cardiopulmonary resuscitation. The median clamp time was 108 min (interquartile range 89-157) and circulatory arrest time was 25 min (interquartile range 19-31). Concomitant procedures included 11 coronary artery bypass grafting (35%), 4 root replacements (13%) and 1 total arch replacement (3%). Overall, in-hospital mortality was 67%: 10 of 11 (91%) patients with extracorporeal membrane oxygenation and 11 of 19 patients (55%) with intra-aortic balloon pump expired. There were no intra-aortic balloon pump-specific aortic complications (i.e. aortic rupture, extension of dissection).</p><p><strong>Conclusions: </strong>Outcomes after extracorporeal membrane oxygenation support in acute type A dissection were discouraging. There may be a role for intra-aortic balloon pump following acute type A dissection repair to allow patients to recover from cardiogenic shock in the selected patients.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"342"},"PeriodicalIF":1.5,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of cardiac rehabilitation exercises incorporating music movement therapy on atrial fibrillation patients: a forward-looking investigation.","authors":"Yue Zhang, Li Dong, Liya Zhang, Ailing Tang, Yuhan Xing, Haoyong Zhang, Fanglei Xu","doi":"10.1186/s13019-025-03582-9","DOIUrl":"10.1186/s13019-025-03582-9","url":null,"abstract":"<p><strong>Objective: </strong>Cardiac rehabilitation (CR) stands as a crucial therapeutic measure for improving the prognosis of individuals afflicted with cardiovascular ailments. This investigation seeks to examine the efficacy of CR training that integrates music and movement therapy in addressing atrial fibrillation (AF) patients.</p><p><strong>Methods: </strong>From January 2023 to January 2024, a total of 144 AF patients who sought medical attention at Tongji Hospital in Shanghai were selected as research subjects. These participants were evenly divided into three groups through randomization: 48 patients in the music-movement CR group, 49 in the movement CR group, and 47 in the conventional CR group. Patients in the conventional CR group underwent standard CR training, while those in the movement CR group participated in CR training centered on movement therapy. The music-movement CR group engaged in CR training that harmoniously combined music and movement therapy. The intervention spanned a period of six months for all three groups. Post-intervention, comparative analyses were performed on cardiac function, AF duration, complication incidence, adverse emotional states, sleep quality, and quality of life among the three groups.</p><p><strong>Results: </strong>Post-intervention, compared to the Conventional CR group, the Music-Movement CR group demonstrated: Significantly lower LVEDD (43.65 ± 3.87 mm vs. 50.20 ± 3.88 mm, p < 0.001) and higher LVEF (48.47 ± 3.69% vs. 42.63 ± 4.12%, p < 0.001). Shorter AF duration (3.41 ± 0.14 days vs. 4.19 ± 0.67 days, p < 0.001) and lower complication rate (6.25% vs. 21.28%, p = 0.033). Lower SAS (50.31 ± 5.71 vs. 58.69 ± 6.45, p < 0.001) and SDS scores (51.15 ± 5.53 vs. 57.52 ± 6.17, p < 0.001). Higher AFEQT total scores (84.87 ± 14.67 vs. 72.31 ± 14.13, p < 0.001). Improvements in the Music-Movement CR group were also consistently superior to the Movement CR group across these metrics (all p < 0.05 or lower).</p><p><strong>Conclusion: </strong>Implementing CR training that incorporates music and movement therapy for AF patients demonstrably enhances cardiac function, curtails AF duration and complication rates, and ameliorates emotional states, sleep quality, and overall quality of life.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"341"},"PeriodicalIF":1.5,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delayed recurrence of complete atrioventricular block following ablation for premature ventricular complexes.","authors":"Yao Zhao, Xueyan Ding, Jiang Cao, Xinmiao Huang","doi":"10.1186/s13019-025-03570-z","DOIUrl":"10.1186/s13019-025-03570-z","url":null,"abstract":"<p><p>A 77-year-old man was admitted for catheter ablation due to frequent premature ventricular complexes (PVCs). Activation mapping revealed that the earliest ventricular activation during the PVC was recorded on the left upper septum, where a clear His bundle electrogram was recorded during sinus rhythm. Radiofrequency ablation was performed with step-wise incremental application of the radio frequency energy. AV block was observed twice during RF ablation and disappeared within 5 s after stopping energy application each time. As he exhibited normal atrioventricular conduction, the patient was discharged home the following day. Five days after discharge, he experienced recurrent syncope, with ECG showing complete heart block. Although continuous telemetric echocardiogram monitoring revealed resolution of the complete atrioventricular block after 8 days, it recurred 5 days after. Follow-up evaluation of the pacemaker revealed persistent atrioventricular block at 3 and 6 months.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"339"},"PeriodicalIF":1.5,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12363021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144873357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shortness of breath on a mustard patient: multidisciplinary approach improves outcomes.","authors":"Isabella Casallas-Gutierrez, Tomas Chalela, Nestor Sandoval, Laura Acosta-Izquierdo, Julian Forero, Stephany Luna-Pisciotti, Carlos-Eduardo Guerrero-Chalela","doi":"10.1186/s13019-025-03559-8","DOIUrl":"10.1186/s13019-025-03559-8","url":null,"abstract":"<p><strong>Background: </strong>Dextro-transposition of the great arteries post-atrial switch patients may experience complications like baffle stenosis. While percutaneous interventions are the standard treatment, severe calcification can require uncommon alternatives such as surgical redo procedures.</p><p><strong>Case presentation: </strong>We present a 27-year-old female with a history of dextro-transposition of the great arteries corrected with an atrial switch at 11 months old who presented with shortness of breath. Imaging revealed severe superior baffle obstruction. Due to extensive baffle calcification, surgical reoperation with total baffle replacement was performed. The patient recovered well, with sustained symptomatic relief and normal biventricular function at follow-up.</p><p><strong>Conclusions: </strong>This case underscores the importance of multimodal imaging for diagnosing complex baffle complications and the critical role of multidisciplinary teams in planning tailored interventions. Surgical redo remains viable in cases where percutaneous approaches are contraindicated, ensuring favorable outcomes in challenging scenarios.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"337"},"PeriodicalIF":1.5,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12355790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elucidating the role of LGALS3BP in coronary atherosclerosis: integrating bioinformatics and machine learning for advanced insights.","authors":"Suzhen Zhao, Chuanxin Zhao, Linlin Wang, Baoe Cheng, Man Zheng, Xiuyun Wang","doi":"10.1186/s13019-025-03462-2","DOIUrl":"10.1186/s13019-025-03462-2","url":null,"abstract":"<p><strong>Background: </strong>Atherosclerosis (AS) is increasingly recognized as a chronic inflammatory disease that significantly impacts vascular health and contributes to cardiovascular disorders. LGALS3BP, a well-studied molecule, plays key roles in various physiological and pathological processes.</p><p><strong>Methods: </strong>We identified LGALS3BP as a central focus through integrative analysis of DEGs across multiple datasets (GSE43292 and GSE9820) from the GEO database, combined with immune-related gene sets from the ImmPort database. Advanced analytical techniques, including Lasso regression and SVM-RFE, were used to refine gene selection. GSEA and GSVA revealed significant enrichment in immune-related pathways. The relationship between LGALS3BP expression and immune processes was explored using CIBERSORT and ESTIMATE algorithms, which indicated a positive association between higher LGALS3BP expression and increased immune cell infiltration.</p><p><strong>Results: </strong>Among the 10 DEGs associated with LGALS3BP, 13 hub genes were identified via LASSO and SVM-RFE analyses. Functional assays highlighted LGALS3BP's involvement in viral defense, cytokine production, and immune cascades. Increased expression of LGALS3BP was positively correlated with activated dendritic cells, NK cells, memory CD4 T cells, naïve CD4 T cells, CD8 T cells, follicular helper T cells, gamma delta T cells, and regulatory T cells (Tregs), while negatively associated with resting mast cells, M0 macrophages, and eosinophils.</p><p><strong>Conclusions: </strong>Our research elucidates the complex relationship between LGALS3BP and AS, positioning it as a potential novel biomarker for diagnosis and disease monitoring. These findings lay the groundwork for future studies and suggest that targeting LGALS3BP-related pathways could enhance our understanding of AS.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"338"},"PeriodicalIF":1.5,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12355831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting spread through air space of lung adenocarcinoma based on deep learning and machine learning models.","authors":"Zengming Wang, Lingxin Kong, Bin Li, Qingtao Zhao, Xiaopeng Zhang, Huanfen Zhao, Wenfei Xue, Wei Li, Shun Xu, Guochen Duan","doi":"10.1186/s13019-025-03568-7","DOIUrl":"10.1186/s13019-025-03568-7","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to develop a machine learning model that can predict spread through air space (STAS) of lung adenocarcinoma preoperatively. STAS is associated with poor prognosis in invasive lung adenocarcinoma. Therefore non-invasive and accurate pre-surgical prediction of STAS in patients with lung adenocarcinoma is essential for individualised patient management.</p><p><strong>Methods: </strong>We included 138 patients with invasive lung adenocarcinoma who underwent lobectomy, collected their preoperative imaging data and clinical features, built a model for predicting STAS using machine learning and deep learning methods, and validated the efficacy of the model. Finally a nomogram was created based on logistic regression (LR).</p><p><strong>Results: </strong>Imaging histology features showed good model efficacy in both the training set (LR AUC = 0.764) and the test set (LR AUC = 0.776), and we combined the imaging histology and clinical features to jointly build a nomogram graph (AUC = 0.878), extracted the deep learning features, and built a machine learning model based on the ResNET50 algorithm, where the LR AUC = 0.918.</p><p><strong>Conclusions: </strong>This presented radiomics model can be served as a non-invasive for predicting STAS in Infiltrating lung adenocarcinoma.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"336"},"PeriodicalIF":1.5,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12351919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}