Journal of Autism and Developmental Disorders最新文献

筛选
英文 中文
The Comprehension of Grammatical Structures in a Pediatric Population with ASD and Epilepsy: A Comparative Study. 患有自闭症和癫痫的儿童对语法结构的理解:比较研究
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-04-01 Epub Date: 2024-02-23 DOI: 10.1007/s10803-024-06291-9
Alejandro Cano Villagrasa, Nadia Porcar Gozalbo, Beatriz Valles González, Miguel López-Zamora
{"title":"The Comprehension of Grammatical Structures in a Pediatric Population with ASD and Epilepsy: A Comparative Study.","authors":"Alejandro Cano Villagrasa, Nadia Porcar Gozalbo, Beatriz Valles González, Miguel López-Zamora","doi":"10.1007/s10803-024-06291-9","DOIUrl":"10.1007/s10803-024-06291-9","url":null,"abstract":"<p><p>Autism Spectrum Disorder (ASD) and epilepsy represent a comorbidity that negatively influences the proper development of linguistic competencies, particularly in receptive language, in the pediatric population. This group displays impairments in the auditory comprehension of both simple and complex grammatical structures, significantly limiting their performance in language-related activities, hampering their integration into social contexts, and affecting their quality of life. The main objective of this study was to assess auditory comprehension of grammatical structures in individuals with ASD and epilepsy and compare the results among the three groups. A non-experimental cross-sectional study was designed, including a total of 170 participants aged between 7 and 9 years, divided into three groups: a group with ASD, a group with epilepsy, and a comorbid group with both ASD and epilepsy (ASDEP). The comprehension of grammatical structures was assessed using the CEG and CELF-5 instruments. Statistical analyses included MANOVA and ANOVA to compare scores between groups to verify associations between study variables. The results indicate that the group with ASD and epilepsy performed worse compared to the ASD and epilepsy-only groups, respectively. Additionally, a significant and directly proportional association was observed among all variables within the measures of grammatical structure comprehension. The neurological damage caused by epilepsy in the pediatric population with ASD leads to difficulties in understanding oral language. This level of functioning significantly limits the linguistic performance of these children, negatively impacting their quality of life and the development of core language skills.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":"1379-1388"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139931219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autistic People's Perspectives on Functioning Labels and Associated Reasons, and Community Connectedness. 自闭症患者对功能标签和相关原因以及社区联系的看法。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-04-01 Epub Date: 2024-03-20 DOI: 10.1007/s10803-024-06316-3
Nathan Keates, Farradeh Martin, Krysia Emily Waldock
{"title":"Autistic People's Perspectives on Functioning Labels and Associated Reasons, and Community Connectedness.","authors":"Nathan Keates, Farradeh Martin, Krysia Emily Waldock","doi":"10.1007/s10803-024-06316-3","DOIUrl":"10.1007/s10803-024-06316-3","url":null,"abstract":"<p><strong>Purpose: </strong>Functioning labels have been used in relation to autistic people and differentiating between support needs. The main purpose of our study was to identify perspectives regarding language about being autistic. In regard to themselves and functioning. Furthermore, we investigated the influential factor of community connectedness on use of language acceptability and functioning labels.</p><p><strong>Methods: </strong>516 autistic respondents completed our survey. We asked about demographic characteristics, how respondents would like autistic people to be termed in the survey, and their acceptability (person with autism, Aspergers, disorder, conditions, living with autism, autistic). We also asked about respondents? Autistic Community Connectedness, acknowledging the implicit nature of language and identity (Stets & Serpe in New directions in identity theory and research, Oxford University Press, 2016). The main focus of our survey was whether or not to use functioning labels, and the supporting rationale.</p><p><strong>Results: </strong>97% of respondents stated that they find the term 'autistic' acceptable. Respondents who did see merit in using functioning labels to describe autistic people also reported not necessarily using them about themselves. Community membership was found to impact the participants' language preferences to describe the support needs of autistic people, including the use of functioning labels.</p><p><strong>Conclusion: </strong>The proposed best option for language preferences is not to find consensus but instead, opt for the optimal choice that people find the least offensive or disagreeable. This means using identity-first language and not using functioning labels.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":"1318-1328"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140174815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Direct Comparison of Three Screening Methods for Autism Spectrum Disorder in a High-Likelihood Sibling Population. 直接比较三种自闭症谱系障碍筛查方法在高可能性兄弟姐妹人群中的应用。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-04-01 Epub Date: 2024-03-27 DOI: 10.1007/s10803-024-06294-6
Chui Mae Wong, Nurhafizah Mohd Zambri, Hui Hua Fan, Lily H S Lau, L Mary Daniel, Hwan Cui Koh
{"title":"A Direct Comparison of Three Screening Methods for Autism Spectrum Disorder in a High-Likelihood Sibling Population.","authors":"Chui Mae Wong, Nurhafizah Mohd Zambri, Hui Hua Fan, Lily H S Lau, L Mary Daniel, Hwan Cui Koh","doi":"10.1007/s10803-024-06294-6","DOIUrl":"10.1007/s10803-024-06294-6","url":null,"abstract":"<p><p>Targeted screening of children at increased likelihood of autism is recommended. However, autism screening tools are usually validated for use mainly in low-likelihood populations. This study compared the accuracy of the Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT-R/F), the ASDetect app, and the Social Attention and Communication Surveillance, Revised (SACS-R). Siblings of autistic children underwent autism screening at 12, 18 and 30 months old. At each visit, caregivers completed the M-CHAT-R/F and ASDetect while trained nurses tested the siblings using the SACS-R. At 36 to 48 months, the siblings underwent an Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) assessment. 189 siblings were screened, 141 completed the study, and 32 were confirmed to have autism. Although not validated for use at 12 months, the M-CHAT-R/F had the best sensitivity among the three tools for this age group, suggesting that early signs are already apparent to caregivers. The M-CHAT-R/F had overall better sensitivity (0.72-0.83) across all age groups, but with overall lower specificity (0.55-0.77). The SACS-R and ASDetect had better positive predictive values at 18 and 30 months (0.60-0.68), while the M-CHAT-R/F was 0.43-0.48. Negative predictive values were generally high across all three tools across all age groups (0.78-0.93). Targeted screening of children at high likelihood of autism yielded a detection rate of 22.7% and should therefore be implemented routinely to facilitate early detection and intervention. The performance of autism screening tools should be examined in higher-likelihood populations for targeted screening of these children.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":"1274-1285"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Friendship in Autism Spectrum Disorder Is Related to Diverse Developmental Changes Between Toddlerhood and Adolescence. 自闭症谱系障碍患者的友谊与幼儿期到青春期的不同发育变化有关。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-04-01 Epub Date: 2024-03-08 DOI: 10.1007/s10803-024-06284-8
Ronit Saban-Bezalel, Esther Ben-Itzchak, Ditza A Zachor
{"title":"Friendship in Autism Spectrum Disorder Is Related to Diverse Developmental Changes Between Toddlerhood and Adolescence.","authors":"Ronit Saban-Bezalel, Esther Ben-Itzchak, Ditza A Zachor","doi":"10.1007/s10803-024-06284-8","DOIUrl":"10.1007/s10803-024-06284-8","url":null,"abstract":"<p><strong>Purpose: </strong>Follow-up studies of children diagnosed with autism spectrum disorder (ASD) in early childhood that focus on friendship formation during adolescence are scarce. The present study focused on exploring characteristics possibly related to the ability to establish friendships during adolescence among children diagnosed with ASD in toddlerhood.</p><p><strong>Methods: </strong>The cohort included 43 participants who underwent comprehensive assessments during toddlerhood and adolescence. Participants were divided into two groups [Friendship(+)/Friendship(-)] based on (1) adolescent social insight as assessed by professionals and (2) parental and adolescent self-reports regarding having or not having friends. No differences in IQ, ASD symptoms, or adaptive behavior during early childhood were found between the two groups.</p><p><strong>Results: </strong>Different and better changes in social communication, adaptive socialization, and daily living skills were observed for the Friendship(+) group. Adolescents with ASD in the Friendship(+) group exhibited greater social independence. Attention-deficit/hyperactivity disorder incidence, anxiety symptom severity, and placement in mainstream or special education classes did not differ between the two groups.</p><p><strong>Conclusion: </strong>This long-term study highlights that for children with ASD, longitudinal growth in social communication and adaptive functioning is possible, highly important for and related to the development of the complex ability to establish friendship.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":"1341-1352"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140059471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: The Psychometric Properties of Autism Mental Status Examination (AMSE) in Turkish Sample. 修正:土耳其样本自闭症心理状态检查(AMSE)的心理测量特性。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-04-01 DOI: 10.1007/s10803-025-06813-z
Yavuz Meral, Alperen Bıkmazer, Abdurrahman Cahid Örengül, Süleyman Çakıroğlu, Esra Altınbilek, Fulya Bakır, Bilgihan Bıkmazer, Ayman Saleh, Vahdet Görmez
{"title":"Correction to: The Psychometric Properties of Autism Mental Status Examination (AMSE) in Turkish Sample.","authors":"Yavuz Meral, Alperen Bıkmazer, Abdurrahman Cahid Örengül, Süleyman Çakıroğlu, Esra Altınbilek, Fulya Bakır, Bilgihan Bıkmazer, Ayman Saleh, Vahdet Görmez","doi":"10.1007/s10803-025-06813-z","DOIUrl":"https://doi.org/10.1007/s10803-025-06813-z","url":null,"abstract":"","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brief Report: Longitudinal Trajectory of Working Memory in School-Aged Children on the Autism Spectrum: Period of High Plasticity and "Late Bloomers". 简要报告:自闭症谱系学龄儿童工作记忆的纵向轨迹:高可塑性时期和“晚熟期”。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-04-01 Epub Date: 2023-04-06 DOI: 10.1007/s10803-023-05960-5
Sohyun An Kim, Connie Kasari
{"title":"Brief Report: Longitudinal Trajectory of Working Memory in School-Aged Children on the Autism Spectrum: Period of High Plasticity and \"Late Bloomers\".","authors":"Sohyun An Kim, Connie Kasari","doi":"10.1007/s10803-023-05960-5","DOIUrl":"10.1007/s10803-023-05960-5","url":null,"abstract":"<p><strong>Purpose: </strong>While working memory (WM) is a powerful predictor for children's school outcomes, autistic children are more likely to experience delays. This study compared autistic children and their neurotypical peers' WM development over their elementary school years, including relative growth and period of plasticity.</p><p><strong>Methods: </strong>Using a nationally-representative dataset, latent growth models were built to examine periods of high plasticity and the relationship between children's performance upon school entry and their relative growth.</p><p><strong>Results: </strong>While both groups made steeper gains during the early school years, autistic children's period of highest plasticity was prolonged by 1 year, which suggests a larger window for interventions. Further, autistic children who started kindergarten with poorer WM were more likely to make rapid growth during the last 3 years of elementary school, which is when their neurotypical peers' development started to plateau.</p><p><strong>Conclusion: </strong>Findings should prompt various stakeholders to examine interventions and instructions to maximize autistic children's growth in WM. Further, the continued support and monitoring by educators throughout autistic children's late childhood can be particularly beneficial for the \"late-bloomers.\"</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":"1537-1546"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9307283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Economic Impacts of COVID-19 on Autistic Children and Their Families. COVID-19 对自闭症儿童及其家庭的经济影响。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-04-01 Epub Date: 2024-02-23 DOI: 10.1007/s10803-024-06280-y
Kristy A Anderson, Melissa Radey, Jessica E Rast, Anne M Roux, Lindsay Shea
{"title":"The Economic Impacts of COVID-19 on Autistic Children and Their Families.","authors":"Kristy A Anderson, Melissa Radey, Jessica E Rast, Anne M Roux, Lindsay Shea","doi":"10.1007/s10803-024-06280-y","DOIUrl":"10.1007/s10803-024-06280-y","url":null,"abstract":"<p><strong>Purpose: </strong>We used data from the National Survey of Children's Health to (1) examine differences in economic hardship and safety net program use after the implementation of federal relief efforts, and (2) assess whether the COVID-19 pandemic exacerbated autism-based disparities in hardship and program use.</p><p><strong>Methods: </strong>We examined five dimensions of economic hardship (poverty, food insecurity, medical hardship, medical costs, and foregone work) and four safety net programs (cash assistance, Supplemental Nutrition Assistance Program (SNAP), Special Supplemental Nutrition Program for Women, Infants and Children (WIC), and free or reduced-cost meals). First, we calculated adjusted prevalence and odds ratios to compare pre-COVID (2018-2019) and during COVID (2021) outcomes by autism status. Next, we calculated the adjusted odds of each outcome among autistic children compared to those of children with and without other special healthcare needs at both time points.</p><p><strong>Results: </strong>COVID-19 exacerbated autism-based disparities in food insecurity, SNAP, and public health insurance, but alleviated inequities in medical hardship, foregone work, and cash assistance. Autistic children did not experience declines in food insecurity or increases in SNAP like other children; medical hardship and foregone work decreased more for autistic children; and the magnitude of autism-based differences in public coverage significantly increased during the pandemic.</p><p><strong>Conclusion: </strong>Federal relief efforts likely improved economic outcomes of children; however, these effects varied according to type of hardship and by disability group. Efforts to promote economic well-being among autistic populations should be tailored to the financial challenges most salient to low-income autistic children, like food insecurity.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":"1329-1340"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139931220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Social Validity of Behavioral Interventions: Seeking Input from Autistic Adults. 行为干预的社会有效性:征求自闭症成年人的意见。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-04-01 Epub Date: 2024-03-12 DOI: 10.1007/s10803-024-06297-3
Kaitlynn M P Baiden, Zachary J Williams, Rachel K Schuck, Patrick Dwyer, Mian Wang
{"title":"The Social Validity of Behavioral Interventions: Seeking Input from Autistic Adults.","authors":"Kaitlynn M P Baiden, Zachary J Williams, Rachel K Schuck, Patrick Dwyer, Mian Wang","doi":"10.1007/s10803-024-06297-3","DOIUrl":"10.1007/s10803-024-06297-3","url":null,"abstract":"<p><p>Many in the autistic community have expressed concerns regarding the use of behavioral interventions with autistic children, suggesting that these interventions may not be socially valid. Though behavioral interventions have evolved to be more naturalistic and child-centered, little structured research has been done to explicitly seek autistic perspectives on the acceptability of specific components of behavioral interventions. Autistic adults (N = 235) were recruited online to take the Autism Intervention Attitudes Scale (AIAS), a questionnaire designed to gather feedback on common intervention goals and practices. Results indicate that participants find goals and practices that highlight quality of life, safety, and autistic interactions acceptable, while those that focus on normalization based on neurotypical standards are not. An exploratory graph analysis revealed three communities of goals (\"uncontroversial goals\", \"controversial goals\", and \"social goals\"). Comparison between naturalistic and structured intervention components additionally showed that autistic participants favored naturalistic strategies. These findings are in line with known criticisms of behavioral intervention from autistic adults, but also provide more information on the specific ways in which behavioral interventions can be reformed. This information can guide professionals in the development of appropriate goals and decisions around intervention planning.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":"1172-1186"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140110337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Behavioral Presentation of Autistic Adults in a Forensic Interview. 自闭症成人在法医采访中的行为表现。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-29 DOI: 10.1007/s10803-025-06805-z
Katie Logos, Alliyza Lim, Neil Brewer, Robyn L Young
{"title":"The Behavioral Presentation of Autistic Adults in a Forensic Interview.","authors":"Katie Logos, Alliyza Lim, Neil Brewer, Robyn L Young","doi":"10.1007/s10803-025-06805-z","DOIUrl":"https://doi.org/10.1007/s10803-025-06805-z","url":null,"abstract":"<p><p>Autism diagnostic criteria, and research primarily involving autistic children, highlight verbal and nonverbal behaviors likely to manifest during social interaction that may generate unfavorable impressions of interaction partners (e.g., poor credibility, incompetence). These behaviors are thought to bias evaluations of autistic individuals, particularly within high-stakes contexts (e.g., police or employment interviews). However, the prevalence of those behaviors in autistic adults is unclear. IQ-matched samples of autistic (n = 43) and non-autistic (n = 41) adults participated in a simulated chatroom, exposed to text-based conversations about illegal hacking. Participants were then interviewed about the chatroom in a one-on-one video-recorded online interview with the researcher. We measured the prevalence of 19 verbal and nonverbal behaviors, and memory report characteristics displayed by the interviewees, and investigated differences between the diagnostic groups. Diagnosis had a strong effect on overall behavioral displays but was only associated with minor differences in individual behaviors. Three significant effects indicated greater difficulty interpreting figurative language, longer speech hesitations, and greater verbal intonation for autistic than non-autistic adults. Inter-individual variability within groups and within-individual variability across behaviors highlighted that behaviors were neither ubiquitous nor consistently displayed in combination. There was also a suggestion of more noticeable differences in the behavior of male than female autistic adults. Although minor behavioral differences were detected based on diagnosis, they included behaviors that could lead to negative outcomes for autistic individuals during high-stakes interactions. Whether more pronounced behavioral differences are detected during face-to-face interactions warrants further research.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Psychotropic Medication Use in Hospitalized Children With Autism Spectrum Disorder in China: The Role of Intellectual Disability. 中国住院自闭症谱系障碍儿童精神药物使用的研究:智力障碍的作用
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-27 DOI: 10.1007/s10803-025-06779-y
Wenqing Li, Chenxi Bao, Yupei Ye, Qingxiang Liu, Kangkang Chu, Ya Wang, Xiaoyan Ruan, Huimin Lü, Xi Liu, Xiaoyan Ke
{"title":"Exploring Psychotropic Medication Use in Hospitalized Children With Autism Spectrum Disorder in China: The Role of Intellectual Disability.","authors":"Wenqing Li, Chenxi Bao, Yupei Ye, Qingxiang Liu, Kangkang Chu, Ya Wang, Xiaoyan Ruan, Huimin Lü, Xi Liu, Xiaoyan Ke","doi":"10.1007/s10803-025-06779-y","DOIUrl":"https://doi.org/10.1007/s10803-025-06779-y","url":null,"abstract":"<p><p>Children and adolescents with autism spectrum disorder (ASD) frequently present with mental health comorbidities and behavioral crises, necessitating inpatient care. However, evidence-based guidelines for psychotropic medication use in specialized inpatient settings remain limited, particularly in non-Western contexts. This study examined the clinical characteristics and prescribing patterns among 269 hospitalized ASD patients (2012-2023), with a focus on how intellectual disability (ID) influences medication decisions. A retrospective analysis was conducted using electronic medical records to assess mental disorders, behavioral challenges, and psychotropic medication use at discharge. Logistic regression analyses was performed to examine factors associated with medication prescribing patterns, including the impact of ID status. Psychotropic medication use was highly prevalent (96.7%), with antipsychotics (89.96%) being the most frequently prescribed class, followed by anxiolytics (35.32%) and antidepressants (33.09%). ID was significantly associated with distinct prescribing patterns: patients with ID had 63% lower odds of antidepressant use (aOR = 0.37, p = 0.001) and 80% lower odds of ADHD medication use (aOR = 0.20, p = 0.009), while being more likely to receive antipsychotics (aOR = 2.74, p = 0.049) and experience polypharmacy (aOR = 1.89, p = 0.028). Additionally, disruptive behaviors and age were key predictors of antipsychotic use, whereas suicidal thoughts/attempts or SIBs independently predicted antidepressant prescribing. These findings suggest that ID status plays a critical role in shaping psychotropic prescribing practices beyond symptom severity alone, potentially reflecting diagnostic overshadowing and safety concerns. Future research should focus on developing tailored clinical assessment tools and treatment protocols for ASD populations with and without ID, while enhancing individualized medication monitoring to optimize therapeutic outcomes.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信