Journal of Autism and Developmental Disorders最新文献

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Unintentional Drowning Incidents Involving Children with Autism Spectrum Disorder Treated in US Emergency Departments, 2016-2020. 2016-2020年美国急诊科治疗的自闭症谱系障碍儿童意外溺水事件
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-27 DOI: 10.1007/s10803-025-06769-0
Kristal Xie, Ashley Blanchard, Stanford Chihuri, Matthew Russell, Caleb Ing, Carolyn DiGuiseppi, Guohua Li
{"title":"Unintentional Drowning Incidents Involving Children with Autism Spectrum Disorder Treated in US Emergency Departments, 2016-2020.","authors":"Kristal Xie, Ashley Blanchard, Stanford Chihuri, Matthew Russell, Caleb Ing, Carolyn DiGuiseppi, Guohua Li","doi":"10.1007/s10803-025-06769-0","DOIUrl":"https://doi.org/10.1007/s10803-025-06769-0","url":null,"abstract":"<p><p>Children with autism spectrum disorder (ASD) are at heightened risk of unintentional drowning. We examined the epidemiological patterns of unintentional drowning incidents involving children diagnosed with ASD treated in US emergency departments (EDs). Data for this study came from the 2016-2020 Nationwide ED Sample. Children aged 1-19 years diagnosed with ASD and treated in EDs were identified using ICD-10-CM code F84.0. Weighted multivariable logistic regression models were used to estimate the adjusted odds ratio (aOR) and 95% confidence interval (CI) of drowning-related ED visits associated with ASD. During the study period, there were an estimated 21,226 unintentional drowning-related ED visits in children, including 369 in children diagnosed with ASD. Compared to children without ASD, ED visits for unintentional drownings in children with ASD were more likely to have occurred in swimming pools (47.45% vs. 41.21%), natural water (15.55% vs. 8.82%), and bathtubs (8.08% vs. 4.79%). Among children with ASD, unintentional drowning-related ED visits occurred more commonly in children > 10 years (43.20% vs. 18.19%) and were more likely to result in hospital admission (35.14% vs. 22.02%) than among children without ASD. With adjustment for demographic characteristics, ASD was associated with more than a 2-fold increased odds of ED-treated unintentional drowning (aOR = 2.31; 95% CI 1.84, 2.89). Epidemiologic patterns of unintentional drowning are different between children with and without ASD. Targeted interventions designed to increase supervision, provide adaptive swimming lessons, and enhance environmental safety may reduce the risk of unintentional drownings among children diagnosed with ASD.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What Factors Have Been the Most Helpful and Harmful and When? Identifying Key Impacts on Psychosocial Development According to Autistic Adults and Caregivers. 哪些因素是最有益的,哪些是最有害的?确定自闭症成人和照顾者对心理社会发展的关键影响。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-27 DOI: 10.1007/s10803-025-06800-4
Juliette E Lerner, Hillary Schiltz, Noa Schisterman, Sonja Ziegler, Catherine Lord
{"title":"What Factors Have Been the Most Helpful and Harmful and When? Identifying Key Impacts on Psychosocial Development According to Autistic Adults and Caregivers.","authors":"Juliette E Lerner, Hillary Schiltz, Noa Schisterman, Sonja Ziegler, Catherine Lord","doi":"10.1007/s10803-025-06800-4","DOIUrl":"https://doi.org/10.1007/s10803-025-06800-4","url":null,"abstract":"<p><p>Few studies have asked autistic adults and caregivers directly about what has most positively and negatively impacted their lives. This study sought to: (a) identify positive and negative factors experienced by autistic adults and caregivers; (b) test for within-subject differences in endorsement of promotive factors reported specific to four stages of development; and (c) test for differences in factors between adults with varying cognitive ability (i.e., less cognitively able [LCA; verbal IQ < 70] and more cognitively able [MCA; verbal IQ ≥ 70]). Participants included 91 autistic adults and caregivers. Autistic adults' VIQs ranged from 4 to 139. Participants completed a modified version of the Social/Emotional Functioning Interview which consists of open-ended questions about positive and negative factors experienced across development. Autistic adults and caregivers, regardless of cognitive abilities, frequently reported people supports as more helpful than specific services, aspects of education, or generative activities from early childhood through adulthood. For both cognitive groups, generative activities were increasingly important after childhood. Services were more frequently identified as helpful by LCA caregivers in adulthood, while education was reported more by MCA caregivers and autistic adults. Differences by cognitive ability in negative factors included that more LCA caregivers reported poorly prepared professionals/caregivers as disruptive, while more MCA caregivers and autistic adults reported family conflict and bullying. Positive and negative factors identified through interviews of lived experiences can inform targeted care based on strengths and needs across cognitive abilities and life stages.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intact but Protracted Facial and Prosodic Emotion Recognition Among Autistic Adults. 自闭症成人完整但持续的面部和韵律情绪识别。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-27 DOI: 10.1007/s10803-025-06786-z
Robert M Jertberg, Sander Begeer, Hilde M Geurts, Bhismadev Chakrabarti, Erik Van der Burg
{"title":"Intact but Protracted Facial and Prosodic Emotion Recognition Among Autistic Adults.","authors":"Robert M Jertberg, Sander Begeer, Hilde M Geurts, Bhismadev Chakrabarti, Erik Van der Burg","doi":"10.1007/s10803-025-06786-z","DOIUrl":"https://doi.org/10.1007/s10803-025-06786-z","url":null,"abstract":"<p><p>Despite extensive research efforts, it is unclear how autistic and non-autistic individuals compare in their ability to recognize emotions. Differences in demographic and task factors have been proposed as explanations for divergent findings, but limitations in samples and designs have obscured insight into this possibility. This study investigated the extent of emotion recognition differences among autistic adults and the influence of these factors upon them. We recruited a large sample of autistic and non-autistic adults (N = 1,239) spanning across adulthood (18-76 years). In three online experiments, we compared their performance in recognizing emotions from basic facial expressions, complex expressions conveyed by the eyes alone, and prosodic elements of speech. Autistic individuals performed as well as non-autistic ones in terms of recognition accuracy/sensitivity across measures and emotional categories but took longer to do so. We also detected comparable influences of age, estimated intelligence quotient, and gender (as well as task demands) on both groups. While autistic adults may differ in how they process emotional stimuli, they can do so effectively when given sufficient time. Accordingly, efforts to help autistic individuals improve their ability to recognize emotions may be more fruitful if they focus on efficiency over accuracy. Additionally, reaction time data may offer greater insight than accuracy into differences between autistic and non-autistic individuals on emotion recognition tasks. The similar effects of the demographic and task factors we analyzed on both groups suggest that explanations of the discrepancies in prior literature lie elsewhere.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Autistic Traits and College Adjustment. 更正:自闭症特征和大学适应。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-26 DOI: 10.1007/s10803-025-06792-1
Jane D McLeod, Elizabeth M Anderson
{"title":"Correction: Autistic Traits and College Adjustment.","authors":"Jane D McLeod, Elizabeth M Anderson","doi":"10.1007/s10803-025-06792-1","DOIUrl":"https://doi.org/10.1007/s10803-025-06792-1","url":null,"abstract":"","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factor Analysis of the Autism Spectrum Rating Scales Parent Report 6-18 in a Complex Community Sample. 复杂社区样本自闭症谱系评定量表家长报告6-18的因子分析
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-25 DOI: 10.1007/s10803-025-06801-3
Amy Camodeca
{"title":"Factor Analysis of the Autism Spectrum Rating Scales Parent Report 6-18 in a Complex Community Sample.","authors":"Amy Camodeca","doi":"10.1007/s10803-025-06801-3","DOIUrl":"https://doi.org/10.1007/s10803-025-06801-3","url":null,"abstract":"<p><p>There is a need for research on autism questionnaire psychometrics outside of the standardization sample. This study investigated the factor structure of the Autism Spectrum Rating Scales-Parent report for ages 6-18 (ASRS<sub>p6</sub>) in a well-characterized community sample of 696 children (autism [AUT] n = 231; non-autism [NOT] n = 465; X̄age = 10.03) prospectively evaluated with the Autism Diagnostic Observation Schedule-2, a gold-standard autism diagnostic measure. The original author-identified structure demonstrated poor model fit. Exploratory Factor Analysis with a randomly selected half of the sample (n = 346) suggested retaining 17-items on three factors (Rigid/Sensory, Social, and Executive Function [EF]), explaining 55% of the variance. Confirmatory Factor Analysis with the remaining participants (n = 350) indicated good model fit. Partial measurement invariance was observed for diagnostic (AUT/NOT) and gender (male/female) groups. Correlations with the DSM-5<sub>p6</sub> (an ASRS<sub>p6</sub> scale) were high. Mean differences were observed between AUT/NOT groups for Social; when controlling for age, marginal differences (p = 0.02 - 0.03) were observed for all factors but EF. Social also demonstrated significant AUC regardless of control variables. However, AUC values for Social and other factors, while significant, were in the poor range; correlations with ADOS-2 scores were weak or non-significant. Despite improving the factor structure, the Total-17 does not appear to measure ASD-specific traits. However, these findings provide a basis for further research on ASD questionnaires.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brief Report: False Memory Formation in Autism: The Role of Relational Processing at Study. 简要报告:自闭症的错误记忆形成:关系加工在研究中的作用。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-23 DOI: 10.1007/s10803-025-06803-1
Jennifer Murphy, Eri Ichijo, Geoffrey Bird, Lauren Cooper
{"title":"Brief Report: False Memory Formation in Autism: The Role of Relational Processing at Study.","authors":"Jennifer Murphy, Eri Ichijo, Geoffrey Bird, Lauren Cooper","doi":"10.1007/s10803-025-06803-1","DOIUrl":"https://doi.org/10.1007/s10803-025-06803-1","url":null,"abstract":"<p><strong>Purpose: </strong>Several studies have investigated false memory production in autistic adults, yet it remains unclear whether susceptibility to false memories differs from non-autistic adults and what mechanisms might contribute to any differences. This study examines the mechanisms behind false memory formation in autistic adults using the Deese-Roediger-McDermott (DRM) paradigm.</p><p><strong>Methods: </strong>Participants studied DRM word lists designed to activate a critical word (the 'critical lure). To examine false memory formation and associative processing, participants completed three tasks: a standard recognition test to measure false memory rates, a word stem completion task to assess implicit priming of the critical lure, and a free association task to evaluate explicit associative processing.</p><p><strong>Results: </strong>Autistic individuals showed comparable rates of false memories as non-autistic adults (i.e., falsely reporting having studied the critical lure), were as likely to mention the critical lure on the free association task but showed no tendency to complete word stems with the critical lure when implicitly primed to do so.</p><p><strong>Conclusion: </strong>These findings suggest that autistic adults may rely less on spontaneous spreading of semantic activation during encoding but are capable of engaging in explicit associative processing when directed. The results provide valuable insights into the mechanisms underlying false memory formation in autism.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental Profiles of Young Children Referred for Concern for Autism Spectrum Disorder: DBPNet Study. 关注自闭症谱系障碍的幼儿发展概况:DBPNet研究。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-22 DOI: 10.1007/s10803-025-06777-0
Nancy Roizen, Sandra Friedman, Douglas Vanderbilt, Jaclyn Cacia, Jill Fussell, Robin Hansen, Johannes Hofer, Georgio Sideridis, Ruth E K Stein, William Barbaresi
{"title":"Developmental Profiles of Young Children Referred for Concern for Autism Spectrum Disorder: DBPNet Study.","authors":"Nancy Roizen, Sandra Friedman, Douglas Vanderbilt, Jaclyn Cacia, Jill Fussell, Robin Hansen, Johannes Hofer, Georgio Sideridis, Ruth E K Stein, William Barbaresi","doi":"10.1007/s10803-025-06777-0","DOIUrl":"https://doi.org/10.1007/s10803-025-06777-0","url":null,"abstract":"<p><p>The aim of this study was to compare differences in cognitive, adaptive, and language function in young children referred for concerns for autism spectrum disorder (ASD) who are diagnosed with ASD vs those not diagnosed with ASD (no ASD). This prospective diagnostic study of 349 children < 6 years of age, with 250 diagnosed with ASD and 99 with no ASD, was conducted at 8 diagnostic centers. There were no differences in cognition between those diagnosed with ASD and those with no ASD. As compared to those with no ASD, children with ASD had significantly lower language and adaptive functioning. Children with no ASD had language and adaptive functioning similar to their cognitive function. Differences between developmental domains were also compared within the ASD and no ASD groups. There were no differences between any 2 areas of function in the no ASD group. However, there were significant differences within the ASD group, with cognitive function significantly higher than both language function and adaptive function. This study suggests that a discrepancy between adaptive and language skills beyond that expected based on cognitive function should heighten concern for ASD. Beyond the categorical diagnosis of ASD, it is important to assess all these developmental domains to develop comprehensive plans for interventions.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parent-mediated Interventions Based on the NDBI for Children With ASD: A Systematic Review of Randomized Controlled Trials. 基于NDBI对ASD儿童的父母干预:随机对照试验的系统回顾
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-22 DOI: 10.1007/s10803-025-06791-2
Ying Song, Xiangying Kong, Wenjing Fu, Fuxiang Song
{"title":"Parent-mediated Interventions Based on the NDBI for Children With ASD: A Systematic Review of Randomized Controlled Trials.","authors":"Ying Song, Xiangying Kong, Wenjing Fu, Fuxiang Song","doi":"10.1007/s10803-025-06791-2","DOIUrl":"https://doi.org/10.1007/s10803-025-06791-2","url":null,"abstract":"<p><p>Autism spectrum disorder (ASD) is a developmental disorder that warrants early intervention. This systematic review evaluated the efficacy of parent-mediated natural developmental behavioral interventions (NDBIs) for children aged 0-6 with ASD across various randomized controlled trials (RCTs) and explored the limitations of these interventions. A systematic search was conducted across the PubMed, Web of Science, Embase, and Scopus databases to identify RCTs, and the selected studies were assessed for quality. The search was conducted through January 2024 and identified eight RCTs that, despite varying methodological rigor, collectively suggest benefits for social communication, language skills, and parent‒child interactions in individuals with ASD. Future research should implement standardized intervention protocols, employ sensitive assessment tools, and provide detailed statistical analysis plans to improve the generalizability and reliability of the outcomes of this study.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daily Dynamics of Parental Sleep Quality and Parenting in Chinese Families of Children with Autism Spectrum Disorder. 中国自闭症谱系障碍儿童家庭中父母睡眠质量与父母教养的日常动态。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-22 DOI: 10.1007/s10803-025-06806-y
Hui Wang, Peiyuan Zhao, Xiaoyi Hu, Zhuo Rachel Han
{"title":"Daily Dynamics of Parental Sleep Quality and Parenting in Chinese Families of Children with Autism Spectrum Disorder.","authors":"Hui Wang, Peiyuan Zhao, Xiaoyi Hu, Zhuo Rachel Han","doi":"10.1007/s10803-025-06806-y","DOIUrl":"https://doi.org/10.1007/s10803-025-06806-y","url":null,"abstract":"<p><p>High sleep quality in parents has been linked to positive parenting outcomes, including reduced parenting stress and increased life satisfaction. However, the daily dynamics of these factors remain underexplored, especially in families of children with autism spectrum disorder (ASD). This study examined the reciprocal relationships between daily sleep quality, parenting stress, and life satisfaction among parents of children with ASD. Seventy-five Chinese parents (M = 36.21 years, SD = 3.77 years; 57 mothers) of children with ASD (M = 5.43 years, SD = 1.56 years; 67 boys) participated in a 14-day diary study. Parents reported their subjective sleep quality, parenting stress, and life satisfaction at the same time each day across 7 survey questions. Dynamic structural equation modeling revealed two significant autoregressive effects: parents' perceptions of parenting stress and life satisfaction on a given day tended to persist into the following day. Moreover, better-than-average sleep quality on a given night predicted lower parenting stress and higher life satisfaction the next day. However, daytime fluctuations in parenting stress and life satisfaction did not influence sleep quality that night. hese preliminary findings suggest a unidirectional impact of sleep quality on perceived parenting stress and life satisfaction among these parents. Target interventions aimed at improving sleep quality, such as cognitive-behavioral therapy for insomnia (CBT-I) or structured sleep hygiene programs, may be essential for reducing parenting stress and enhancing life satisfaction in parents of children with ASD. These interventions should prioritize promoting consistent sleep routines and managing stress-related sleep disruptions.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal Exposure to Ambient Particulate Matter and Autism Spectrum Disorder in Children, a Case Control Study in France. 产前暴露于环境颗粒物和儿童自闭症谱系障碍,在法国的一项病例对照研究。
IF 3.2 2区 心理学
Journal of Autism and Developmental Disorders Pub Date : 2025-03-22 DOI: 10.1007/s10803-025-06795-y
Marion Mortamais, Jeanne Sandrine Ongono, Cécile Michelon, Ian Hough, Emie Seyve, Itai Kloog, Cécile Zaros, Marie-Aline Charles, Johanna Lepeule, Amaria Baghdadli
{"title":"Prenatal Exposure to Ambient Particulate Matter and Autism Spectrum Disorder in Children, a Case Control Study in France.","authors":"Marion Mortamais, Jeanne Sandrine Ongono, Cécile Michelon, Ian Hough, Emie Seyve, Itai Kloog, Cécile Zaros, Marie-Aline Charles, Johanna Lepeule, Amaria Baghdadli","doi":"10.1007/s10803-025-06795-y","DOIUrl":"https://doi.org/10.1007/s10803-025-06795-y","url":null,"abstract":"<p><p>A series of epidemiological studies conducted in the United States have consistently shown an increased risk of autism spectrum disorder (ASD) in children associated with pre- and postnatal exposure to ambient particulate matter (PM). In Europe, studies are scarce and results are inconsistent. We aimed to investigate the association between prenatal exposure to PM and the risk of ASD in France. ASD cases were participants from the ELENA cohort. Controls children from the ELFE cohort were matched by sex, year (± 2) and region of birth. Prenatal exposures to PM10 and to PM2.5 were estimated between 2008 and 2013 using innovative hybrid spatio-temporal models developed for France. Conditional logistic regression models adjusted for birth season, parent's age at the child birth and parental education level were run. We included 125 ASD cases and 500 controls. Prenatal PM2.5 and PM10 median (IQR) concentration estimates were respectively 16.3 (3.9) µg/m<sup>3</sup> and 22.9 (6.6) µg/m<sup>3</sup> in the whole sample. The conditional logistic regression models showed Odds Ratios (ORs) (Confidence Interval 95%) for ASD risk of 0.72 (0.52-1.01) and 0.84 (0.58-1.22) for an IQR increase in PM2.5 and PM10 prenatal levels, respectively. When restricting population of ASD cases to children born the same year of controls, ORs were 1.79 (0.80-4.01) and 2.23 (0.71-9.04), respectively. Our results did not show that prenatal exposures to PM2.5 and PM10 were associated with the risk of ASD in children in France.Trial Registration Number NCT02625116.</p>","PeriodicalId":15148,"journal":{"name":"Journal of Autism and Developmental Disorders","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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