Journal of Advanced Veterinary and Animal Research最新文献

{"title":"Relationship between anti-Müllerian hormone concentration and antral follicle count in Colombian creole cows of the Chino Santandereano breed.","authors":"Héctor Javier Narváez, Diego Armando Vega Borda, Esneyder Rugeles Ballesteros, Deicy Villalba Rey, Ricardo Lopes Dias da Costa","doi":"10.5455/javar.2025.l931","DOIUrl":"10.5455/javar.2025.l931","url":null,"abstract":"<p><strong>Objective: </strong>This study was to evaluate the relationship between serum anti-Müllerian hormone (AMH) concentration and antral follicle count (AFC) during the estrous cycle of Colombian Creole cows of the Chino Santandereano breed.</p><p><strong>Materials and methods: </strong>Ten non-lactating, non-pregnant, multiparous cows of the Chino Santandereano breed (<i>Bos taurus taurus</i> adapted), aged between 3 and 7 years, with a body condition of 3.0 ± 0.4 and with normal reproductive tracts at the structural and functional level, were selected and used. For the synchronization of estrus and ovulation, an intravaginal progesterone release device plus 2 mg of estradiol benzoate was applied for 8 days. On day 8, 150 μg of cloprostenol sodium + 300 IU of equine chorionic gonadotropin + 1 mg of estradiol cypionate was administered. This protocol was performed to determine the antral follicular count and to quantify serum AMH levels every 5 days during the estrous cycle.</p><p><strong>Results: </strong>The mean serum AMH concentration and AFC were 725 ± 2.7 pg/ml and 43.4 ± 3.5, respectively. A high correlation was observed between AMH and AFC of <i>r</i> = 0.041; <i>p</i> < 0.0001.</p><p><strong>Conclusion: </strong>The results showed that in Creole cows of the Chino Santandereano breed, there is a high correlation between circulating levels of AMH and ovarian reserve. This mechanism can be used as an endocrine biomarker of the follicular population.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"680-686"},"PeriodicalIF":1.5,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12515259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary nucleotides supplementation enhances the growth and immune responses of the giant freshwater prawn, <i>Macrobrachium rosenbergii</i> (De Man, 1879).","authors":"Belal Hossen, Rokonuzzaman Kibria, Sakib Tahmid Rishan, Muhammad Tofazzal Hossain, Samsul Alam","doi":"10.5455/javar.2025.l932","DOIUrl":"10.5455/javar.2025.l932","url":null,"abstract":"<p><strong>Objective: </strong>The study aimed to assess the impact of dietary nucleotide (NT) supplementation on the growth performance and immune response of juvenile <i>Macrobrachium rosenbergii</i>.</p><p><strong>Materials and methods: </strong>A commercial diet was supplemented with 0.0% (control), 0.10% (T1), 0.15% (T2), and 0.20% (T3) NT for the study. A total of 132 juvenile prawns (0.78 ± 0.03 gm) were randomly distributed into four groups, each having three replicates. Following the 75-day feeding trial, the experimental prawns were exposed to <i>Aeromonas veronii</i> at 8.35 × 10⁵ colony forming unit (cfu)/ml for 7 days through a bath treatment.</p><p><strong>Results: </strong>The growth parameters and survival rate were significantly higher (<i>p</i> < 0.05) in NT-supplemented prawns. Immune-related parameters, e.g., total hemocyte count (THC), hemolymph protein, albumin, globulin, superoxide dismutase, and catalase activity, were also significantly higher (<i>p</i> < 0.05) in NT-supplemented prawns. The challenge of prawn with <i>A</i>. <i>veronii</i> resulted in a significant reduction (<i>p</i> < 0.05) in THC and other biochemical parameters of hemolymph and caused mortality in all the experimental groups. However, significantly higher survival (<i>p</i> < 0.05) against <i>the A</i>. <i>veronii</i> challenge was found in NT-supplemented prawns.</p><p><strong>Conclusion: </strong>It can be concluded that dietary NTs should be supplemented at 0.15%-0.2% to enhance the growth, immunity, and resistance of juvenile <i>M</i>. <i>rosenbergii</i> against <i>A</i>. <i>veronii</i>.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"687-697"},"PeriodicalIF":1.5,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Jackfruit <i>(Artocarpus heterophyllus)</i> seed powder supplementation helps to maintain metabolic homeostasis in both normal and high-sugar diet-fed mice.","authors":"Ohi Alam, Md Kamrul Hasan Kazal, Romana Jahan Moon, Chayon Goswami, Rakhi Chacrabati","doi":"10.5455/javar.2025.l905","DOIUrl":"10.5455/javar.2025.l905","url":null,"abstract":"<p><strong>Objective: </strong>Diabetes mellitus and obesity stand as globally prevalent, life-threatening metabolic diseases. It has been reported that the intake of a high-sugar diet (HSD) increases the risk of developing diabetes and obesity. Therefore, it is necessary to find an alternative supplemental diet that could reduce the harmful consequences of excessive sugar consumption. The current study aimed to explore how jackfruit seed powder (JSP) could potentially prevent metabolic diseases in mice induced by an HSD.</p><p><strong>Materials and methods: </strong>Swiss albino male mice were categorized into six groups fed normal and HSDs with or without JSP supplementation for 8 weeks. After the end of the feeding trial, different parameters related to glucose and lipid homeostasis were measured.</p><p><strong>Results: </strong>We found that 20% of JSP supplementation significantly decreased food intake and body weight gain induced by HSD. Supplementation of JSP reduced the liver weight, white adipose tissue, and brown adipose tissue weight in HSD-fed mice. Moreover, the addition of JSP with HSD improved the glucose tolerance test and reduced the levels of total cholesterol, triglyceride, and low-density lipoprotein cholesterol.</p><p><strong>Conclusion: </strong>These findings indicate that adding 20% JSP is particularly efficient in averting the onset of metabolic diseases induced by an HSD.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"374-384"},"PeriodicalIF":1.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revolutionizing pig farming: Japan's technological innovations and environmental strategies for sustainability.","authors":"Md Kamrul Hasan, Hong-Seok Mun, Eddiemar B Lagua, Hae-Rang Park, Young-Hwa Kim, Md Sharifuzzaman, Jin-Gu Kang, Chul-Ju Yang","doi":"10.5455/javar.2025.l912","DOIUrl":"10.5455/javar.2025.l912","url":null,"abstract":"<p><strong>Objective: </strong>This review examines Japan's pig farming landscape, highlighting key barriers while exploring projects that foster large-scale sustainable development efforts by emphasizing precision technologies integration and policy implications.</p><p><strong>Materials and methods: </strong>A literature review was conducted using keyword searches across Google Scholar, covering studies published between 2018 and 2024. The review encompassed studies on Japan's pig farming, addressing prospects, production metrics, challenges, consumption patterns, market trends, precision technologies, and insights from peer-reviewed journals, credible websites, government reports, and conference proceedings.</p><p><strong>Results: </strong>Japan, one of Asia's largest pork consumers, relies on imports, with domestic production covering only 47.08% of consumption, highlighting a need for greater efficiency. Although small-scale farms continue to dominate the pig industry, the sector is navigating a pivotal shift toward modernization and the expansion of large-scale operations. Farmers face mounting pressures from feed costs, labor shortages, diseases, and strict environmental regulations. Precision pig farming technologies address these by optimizing resource use, enabling early disease detection to reduce costs, improving herd health to promote better welfare, and managing manure to reduce emissions.</p><p><strong>Conclusion: </strong>Integrating large-scale operations with precision pig farming technologies can redefine Japanese pig farming, promoting animal welfare and environmental sustainability. The government must secure financial backing (partial or full subsidies) to support large-scale operations, tax reductions on imported tools, and grants to foster domestic tools and renewable energy innovations to achieve this. Future life-cycle assessment research will be essential for evaluating the long-term environmental impacts, ensuring viability, and promoting sustainability in Japan's pork production sector.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"454-476"},"PeriodicalIF":1.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response of local dairy cows on lipid modulation in different temperature-humidity index (THI) zone.","authors":"Didin Supriat Tasripin, Ujang Hidayat Tanuwiria, Andi Mushawwir, Iin Susilawati","doi":"10.5455/javar.2025.l929","DOIUrl":"10.5455/javar.2025.l929","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the impact of different rearing site zones with varying temperature-humidity index (THI) on the metabolic regulation of lactating local dairy cows.</p><p><strong>Materials and methods: </strong>Forty local dairy cows were used in this study, consisting of 20 in rearing sites with THI 66-70 (Pangalengan) and 78-82 (Sumedang), at 950 and 550 m above sea level, respectively. Basal rations were given every morning and evening, consisting of forage and concentrate. Temperature and humidity were recorded daily to determine the average daily THI. Blood samples in both groups of experimental animals were collected according to standard procedures every month during the 4 months of the experiment. Blood analysis followed procedures based on protocols from KIT Randox (UK), using a spectrophotometer.</p><p><strong>Results: </strong>Lipid activity and regulation appeared higher (<i>p</i> < 0.05) in the group of lactating dairy cows kept at THI comfort zone 66-70 than at THI slight stress zone (78-82). Similarly, blood lipid levels were better (<i>p</i> < 0.05) in the cows in the comfort zone (66-70).</p><p><strong>Conclusion: </strong>The study's results on the impact of the rearing zone of lactating local dairy cows appeared to affect the modulation of lipids in the body. Lipogenesis regulation and metabolism showed higher activity in the group of dairy cows reared in the comfort zone (THI = 66-70) compared to the group of dairy cows reared in the discomfort zone.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"661-667"},"PeriodicalIF":1.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibition of <i>Aeromonas hydrophila</i> and intestinal pathogenic bacteria in Nile tilapia (<i>Oreochromis niloticus</i>) fish by silver nanoparticles.","authors":"Samyah D Jastaniah, Najah M Albaqami","doi":"10.5455/javar.2025.l928","DOIUrl":"10.5455/javar.2025.l928","url":null,"abstract":"<p><strong>Objective: </strong>This research investigated the antibacterial properties of coated silver nanoparticles (CAgNPs) and non-coated silver nanoparticles (NCAgNPs) against bacterial pathogens relevant to Nile tilapia (<i>Oreochromis niloticus</i>), using both <i>in vitro</i> and <i>in vivo</i> methods.</p><p><strong>Materials and methods: </strong>The antibacterial activity of CAgNPs and NCAgNPs was evaluated <i>in vitro</i> against seven bacterial pathogens: <i>Staphylococcus aureus</i>, <i>Bacillus cereus</i>, <i>Escherichia coli</i>, <i>Aeromonas hydrophila</i>, <i>Listeria monocytogenes</i>, <i>Salmonella enterica</i>, and <i>Aeromonas sobria</i>. For the <i>in vivo</i> assessment, 200 Nile tilapia were divided into five treatment groups. The control treatment group was fed a standard diet, but the four treatment groups were fed the standard diet mixed with either 100 or 200 mg/kg of CAgNPs or NCAgNPs, respectively, and the growth indices, antioxidant parameters, immune functions, and intestinal microbiota were assessed. When the experiment was finished, 20 fish of every group were infected with <i>A. hydrophila</i>.</p><p><strong>Results: </strong><i>In vitro</i> assays demonstrated significant antibacterial activity of both CAgNPs and NCAgNPs at 200 µg/ml (p < 0.05) against every bacterial strain that was studied, with moderate activity observed at 100 µg/ml. CAgNPs exhibited larger inhibition zones (30.0 ± 0.58 mm to 36.33 ± 0.88 mm) compared to NCAgNPs, with a minimum inhibitory concentration of 150 µg/ ml. Dietary supplementation with 200 mg/kg CAgNPs improved growth performance, enhanced immune parameters, reduced oxidative stress, and decreased intestinal bacterial load in Nile tilapia. Furthermore, dietary supplementation with 100 mg/kg CAgNPs was more efficient than 100 mg/kg NCAgNPs in reducing intestinal bacterial colonization in fish.</p><p><strong>Conclusion: </strong>These findings indicate the possibility of CAgNPs as an efficient antimicrobial factor in aquaculture. CAgNPs may offer a promising alternative to conventional antibiotics by improving tilapia health and antioxidant status, enhancing immune function, and increasing disease resistance.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"647-660"},"PeriodicalIF":1.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and characteristics of foreign body-induced upper gastrointestinal obstruction in dogs.","authors":"Lalita Laiket, Wijit Sutthiprapa, Suchawalee Khattiya, Pimjai Temwichitr, Jatuporn Rattanasrisomporn, Naris Thengchaisri","doi":"10.5455/javar.2025.l924","DOIUrl":"10.5455/javar.2025.l924","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;This study aimed to identify, categorize, and compare gastrointestinal foreign bodies in dogs, with a particular focus on those causing obstruction. The study also sought to distinguish between foreign body occurrences in the esophagus and the stomach, including the types of materials such as bones, plastic bags, fruit seeds, stones, and wires.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective study was conducted on 261 dogs (151 males and 110 females) with foreign bodies lodged in the esophagus (&lt;i&gt;n =&lt;/i&gt; 111) or stomach (&lt;i&gt;n =&lt;/i&gt; 150). The sample consisted of 188 small dogs (&lt;12 kg), 41 medium-sized dogs (12-24 kg), and 32 large dogs (&gt;24 kg).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The study's findings indicate a higher prevalence of gastric foreign bodies (57.47%) compared to esophageal foreign bodies (42.53%). Small breeds dominated esophageal cases (92.79%), with only a small percentage being medium breeds (7.21%). In contrast, gastric cases included a high number of small breeds (56.67%), as well as significant percentages of medium (22.00%) and large breeds (21.33%). Small-breed dogs were more likely to have foreign bodies in the esophagus, while larger dogs (medium and large breeds) were more likely to have them in the stomach (&lt;i&gt;p&lt;/i&gt; &lt; 0.001). Distinct material patterns emerged between the esophagus and stomach. Notably, the esophagus showed a higher incidence of bones (61.26%) and dried dog snacks (23.42%) compared to the stomach (2.67% and 0.00%, respectively). Conversely, the stomach exhibited a higher incidence of fabrics (20.00% &lt;i&gt;vs.&lt;/i&gt; 1.80%), plant materials (18.67% &lt;i&gt;vs.&lt;/i&gt; 4.50%), metallic objects (18.00% &lt;i&gt;vs.&lt;/i&gt; 8.11%), rocks (12.67% &lt;i&gt;vs.&lt;/i&gt; 0.9%), rubber materials (10.67% &lt;i&gt;vs.&lt;/i&gt; 0.00%), plastic materials (6.67% &lt;i&gt;vs.&lt;/i&gt; 0.00%), and hairballs (2.67% &lt;i&gt;vs.&lt;/i&gt; 0.00%), respectively. A temporal analysis revealed that within the esophagus, 28.83% of cases underwent foreign body removal within 24 h, 56.76% within 2-7 days, and 14.41% after more than 7 days. For foreign bodies within the stomach, removal occurred in 23.33% of cases within 24 h, 30.00% within 2 to 7 days, 22.00% after more than 7 days, and 24.67% at an unknown timing. A total of 111 cases involved foreign bodies lodged in the esophagus, and 150 cases involved items stuck in the stomach. Endoscopic methods were primarily employed to remove foreign bodies, with surgical intervention required for 4 (3.60%) esophageal and 8 (5.30%) gastric cases, including noncrushable bones and resistant items such as rubber ducks. In dogs with complete follow-up, surgical removal of esophageal foreign bodies had a higher mortality rate (3/4, 75.00%) compared with endoscopic removal (3/56, 5.36%) (&lt;i&gt;p&lt;/i&gt; &lt; 0.002), while no mortality was observed in dogs with gastric foreign bodies undergoing surgical or endoscopic removal (&lt;i&gt;p&lt;/i&gt; = 0.149).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Esophageal foreign bodies were primarily composed of bones and dr","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"601-609"},"PeriodicalIF":1.5,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of dietary supplementation with biological zinc, selenium nanoparticles, and their combination on growth, carcass characteristics, blood parameters, and meat quality in broiler chickens.","authors":"Reem Hasaballah Alhasani","doi":"10.5455/javar.2025.l918","DOIUrl":"10.5455/javar.2025.l918","url":null,"abstract":"<p><strong>Objective: </strong>This study examined the impacts of feeding zinc and selenium (SeNPs) nanoparticles and their combinations (ZnNPs and SeNPs and ZnNPs + SeNPs) on growth efficiency, the carcass, blood indicators, and meat criteria traits in chickens during 38 days.</p><p><strong>Materials and methods: </strong>Two hundred forty (Cobb 500) 7-day-old chicks were divided in entirely random form into 4 groups, each group divided into 6 replicates of 10 chicks. Dietary supplements were given in accordance with a corn-soybean diet in the following 4 test treatments: 0.0 (T0), 1.5 mg/kg SeNPs (T1), 2.0 mg/kg ZnNPs (T2), and 1.5 mg/kg SeNPs + 2.0 mg/kg ZnNPs (T3). Water and feed were provided at all times during the 38-day period.</p><p><strong>Results: </strong>The findings concluded that the mixing of SeNPs, ZnNPs, or its combination as feed addition improved rates of growth, as illustrated by higher \"body weight\" and reduced \"feed intake and feed conversion ratio\". The results indicated that there were no appreciable variations (<i>p</i> ≤ 0.05) in carcass measurements between the treatments. Additionally, hematological markers showed significant improvements, with decreased amounts of \"uric acid, creatinine, aspartate aminotransferase, alanine aminotransferase, total cholesterol, and low-density lipoprotein\", while high-density lipoprotein values increased in chicks feeding ZnNPs or SeNPs compared to the control group in eating. Additionally, T3 levels were lowered and T4 levels were raised when SeNPs, ZnNPs, or a mixture of the two were given. Additionally, these treatments affected immunological responses, leading to increased immunoglobulin (IgM and IgG) levels. By increasing moisture quantity while maintaining carcass texture, aroma, tenderness, juiciness, and acceptability scores, these supplements also had an impact on meat quality.</p><p><strong>Conclusion: </strong>The addition of SeNPs and ZnNPs to the chicken diet enhanced immune system function, growth, and blood criteria. This raises the possibility of a substitute for popular growth boosters and organic immune modulators.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"539-548"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The dual role of extracellular vesicles derived from animal and human immune cells: A systematic review.","authors":"Joseph Bagi Suleiman, Norhayati Liaqat Ali Khan, Maryam Azlan","doi":"10.5455/javar.2025.l915","DOIUrl":"10.5455/javar.2025.l915","url":null,"abstract":"<p><p>This review aims to examine the functions of extracellular vesicles (EVs) originating from animal and human immune cells, with a focus on their roles in immunomodulation and therapeutic potential. It highlights their dual effects in infection and autoimmunity, cancer treatment, inflammatory conditions, and regenerative medicine while also addressing the challenges in standardizing EV production, isolation, and characterization for clinical applications. This review highlights the need for robust protocols to advance EV-based therapies. It also synthesizes current literature on immune cell-derived EVs, with a focus on their mechanisms of action in intercellular communication, immune modulation, and therapeutic delivery. Additionally, it examines studies that explore the regenerative potential of immune cell-derived EVs and discusses the technical and methodological challenges involved in EV research and clinical translation. EVs from immune cells can either boost or reduce immune responses in tumor therapy, which greatly affects how cancer develops and how well treatments work. These EVs also show promise in managing inflammatory diseases through immune modulation and targeted therapeutic delivery. Furthermore, immune cell-derived EVs possess regenerative properties, contributing to tissue repair and the maintenance of homeostasis. Despite these promising roles, challenges related to the standardization of EV production, isolation, and characterization continue to impede clinical translation, for improved protocols to ensure reproducibility and scalability. Immune cell-derived EVs possess substantial therapeutic potential in cancer treatment, inflammatory diseases, and regenerative medicine. These tiny membrane-bound particles, naturally released by immune cells, carry bioactive molecules that can modulate immune responses, suppress tumor growth, or promote tissue repair. However, before these therapies can be widely used in clinics, key challenges must be addressed, particularly in standardizing their production, characterization, and quality control.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"497-515"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and identification of local white-rot fungi from West Sumatra and their potential for biodelignification of ruminant feed.","authors":"Eli Ratni, Lendrawati Lendrawati, Fadilla Hefzi, Mufidhatul Muqarramah","doi":"10.5455/javar.2025.l920","DOIUrl":"10.5455/javar.2025.l920","url":null,"abstract":"<p><strong>Objective: </strong>This research aimed to isolate and identify potential white-rot fungi from various locations in West Sumatra, Indonesia, that could be used for biodelignification of animal feed ingredients.</p><p><strong>Materials and methods: </strong>Wood samples with fungal infections were directly observed, and the visual method was employed to collect samples. The purified white-rot fungi isolates underwent the Bavendamm test to evaluate their biodelignification capabilities.</p><p><strong>Results: </strong>Eight of the 15 purified white-rot fungi isolates demonstrated positive results in the Bavendamm test, indicating their potential for biodelignification. Further analysis revealed the presence of three indigenous white-rot fungi species in West Sumatra: <i>Exidia</i> sp., <i>Trametes</i> sp., and <i>Phanerochaete</i> sp. These findings highlight the richness of white-rot fungi biodiversity in the region and underscore their suitability for lignin degradation in animal feed ingredients. Additionally, the successful isolation and identification of these fungi represent a crucial step toward sustainable biotechnological applications in livestock farming.</p><p><strong>Conclusion: </strong>The identified white-rot fungi have shown promising capabilities for lignin degradation in animal feed ingredients. However, further research is essential to ascertain the optimal enzyme ratio for lignin degradation and to enhance the identification techniques for a broader range of white-rot fungi species. This study provides a foundational step toward improving animal feed quality in the region, especially for ruminants.</p>","PeriodicalId":14892,"journal":{"name":"Journal of Advanced Veterinary and Animal Research","volume":"12 2","pages":"558-564"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12506724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}