Jornal Brasileiro De Pneumologia最新文献_第8页

Out with the old - advancements and shortcomings of the updated 9th edition of the Tumor, Node, Metastasis (TNM) classification system for lung cancer. 总结更新后的第9版肺癌肿瘤、淋巴结、转移（TNM）分类系统的旧进展和不足。

IF 3 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.36416/1806-3756/e20250022

Pedro Magalhães Ferreira, Rui Campos, Carolina Valente, Joana Ferreira, Cláudia Freitas, Catarina Sousa, David Araújo, Hélder Novais Bastos, Adriana Magalhães, Maria Gabriela O Fernandes

{"title":"Out with the old - advancements and shortcomings of the updated 9th edition of the Tumor, Node, Metastasis (TNM) classification system for lung cancer.","authors":"Pedro Magalhães Ferreira, Rui Campos, Carolina Valente, Joana Ferreira, Cláudia Freitas, Catarina Sousa, David Araújo, Hélder Novais Bastos, Adriana Magalhães, Maria Gabriela O Fernandes","doi":"10.36416/1806-3756/e20250022","DOIUrl":"10.36416/1806-3756/e20250022","url":null,"abstract":"Objectives: The 9th edition of the Tumor, Node, Metastasis (TNM-9) lung cancer classification is set to replace the 8th edition (TNM-8) starting in 2025. Key updates include the splitting of the mediastinal nodal category N2 into single- and multiple-station involvement, as well as the classification of multiple extrathoracic metastatic lesions as involving a single organ system (M1c1) or multiple organ systems (M1c2). This study aimed to assess how the TNM-9 revisions affect the final staging of lung cancer patients and how these changes correlate with overall survival (OS).Methods: This retrospective cohort study included patients diagnosed with lung cancer between 2018 and 2021, who were staged according to both TNM-8 and TNM-9 criteria. The staging classifications were analyzed and compared in relation to OS.Results: Among a total of 914 patients, 42 were re-staged using TNM-9. Of the 382 patients classified as stage IVB, 55.9% were reclassified as M1c2. Despite an absolute increase in mean OS for patients re-staged from IIB to IIA and from IIIA to IIB, the observed differences were not statistically significant. Median OS differed significantly both within stage IVB and between patients with M1c2 disease and other stage IV subgroups. Multi-organ metastatic disease was an independent predictor of poorer OS, regardless of age, sex, performance status, and oncologic treatment.Conclusions: TNM-9 improves prognostic accuracy in lung cancer. Although patients with multiple extrathoracic metastases involving different organ systems are not yet independently staged from IVB, they demonstrated significantly poorer OS compared to other advanced-stage patients.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"51 3","pages":"e20250022"},"PeriodicalIF":3.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Burden of respiratory syncytial virus in older adults in Brazil: insights from national surveillance data for the 2022-2023 period. 巴西老年人呼吸道合胞病毒负担：来自2022-2023年期间国家监测数据的见解

IF 3.6 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.36416/1806-3756/e20250068

Ana L Bierrenbach, Olivia T Ranzani

{"title":"Burden of respiratory syncytial virus in older adults in Brazil: insights from national surveillance data for the 2022-2023 period.","authors":"Ana L Bierrenbach, Olivia T Ranzani","doi":"10.36416/1806-3756/e20250068","DOIUrl":"10.36416/1806-3756/e20250068","url":null,"abstract":"Objective: Respiratory syncytial virus (RSV) is a major cause of severe respiratory infections in older adults, particularly those with comorbidities. Despite its clinical impact, RSV remains underdiagnosed and underreported. We sought to assess the burden of RSV in older adults (≥ 60 years of age) in Brazil using national surveillance data for the 2022-2023 period.Methods: We analyzed RSV cases reported in the Sistema de Informação de Vigilância Epidemiológica, identifying them among reported cases of SARS. Cases were examined by demographic characteristics, seasonal trends, and clinical outcomes. RSV cases were compared across defined etiologies.Results: Among 355,230 reported cases of SARS in older adults, 201,965 (56.8%) had a defined etiology, and 1,465 (0.7%) were confirmed as RSV cases. Cases peaked in the second quarter of each year, with the highest incidence in the southern and southeastern regions. Despite a low hospitalization rate (2.3 per 100,000 population), severe outcomes were common: 30.4% required ICU admission, and 24.9% resulted in death, with mortality being highest in those ≥ 90 years of age.Conclusions: RSV-related hospitalizations in Brazil appear underestimated, with reported cases likely representing the most severe spectrum due to underreporting and diagnostic limitations. Seasonal patterns peaked in April-May, and regional differences highlight a higher incidence in the southern and southeastern regions, likely due to epidemiological factors and diagnostic disparities. Although the recent approval of RSV vaccines offers an opportunity to reduce disease burden, successful implementation requires broader access and inclusion in the Brazilian National Immunization Program. Strengthening surveillance, diagnostic capacity, and reporting processes is critical for better disease assessment and public health planning.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"51 3","pages":"e20250068"},"PeriodicalIF":3.6,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Best clinical practice for imaging in cystic fibrosis referral centers in Brazil: a Delphi consensus panel approach. 巴西囊性纤维化转诊中心成像的最佳临床实践：德尔菲共识小组方法。

IF 3 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 DOI: 10.36416/1806-3756/e20250201

Leonardo A Pinto, Antonio Fernando Ribeiro, Edna Lúcia D' Souza, Luciana F V Monte, Vinicius Gomes, Sergio San Juan Dertkigil, Isabela Silva Müller

引用次数: 0

Lymph node with central hypodensity. 中心低密度淋巴结。

IF 3 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 DOI: 10.36416/1806-3756/e20250160

Edson Marchiori, Bruno Hochhegger, Gláucia Zanetti

引用次数: 0

Looking back to move forward: insights from retrospective cohort studies. 回顾前进：来自回顾性队列研究的见解。

IF 3 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 DOI: 10.36416/1806-3756/e20250213

Juliana Carvalho Ferreira, Cecilia M Patino

引用次数: 0

COPD in Brazil: where there's smoke…. 巴西的慢性阻塞性肺病：有烟的地方....

IF 3 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 DOI: 10.36416/1806-3756/e20250235

Frederico Leon Arrabal Fernandes

引用次数: 0

Peculiarities of spirometry in pediatrics. 儿科肺活量测定的特点。

IF 3 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 DOI: 10.36416/1806-3756/e20250165

Mario Arturo Flores-Valadez, Irlanda Alvarado-Amador, Laura Gochicoa-Rangel

引用次数: 0

Pulmonary hyalinizing granulomas. 肺透明性肉芽肿。

IF 3.6 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 DOI: 10.36416/1806-3756/e20240382

Edson Marchiori, Bruno Hochhegger, Gláucia Zanetti

引用次数: 0

Scaling up tuberculosis preventive treatment in Brazil: the ExpandTPT way forward. 在巴西扩大结核病预防治疗：扩大tpt的未来之路。

IF 3.6 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 DOI: 10.36416/1806-3756/e20250154

Anete Trajman, Ezio Távora Dos Santos Filho, Ricardo Arcêncio

引用次数: 0

Evaluation of the accuracy of ChatGPT in answering asthma-related questions. 评价ChatGPT在回答哮喘相关问题中的准确性。

IF 3 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.36416/1806-3756/e20240388

Bruno Pellozo Cerqueira, Vinicius Cappellette da Silva Leite, Carla Gonzaga França, Fernando Sergio Leitão Filho, Sonia Maria Faresin, Ricardo Gassmann Figueiredo, Andrea Antunes Cetlin, Lilian Serrasqueiro Ballini Caetano, José Baddini-Martinez

{"title":"Evaluation of the accuracy of ChatGPT in answering asthma-related questions.","authors":"Bruno Pellozo Cerqueira, Vinicius Cappellette da Silva Leite, Carla Gonzaga França, Fernando Sergio Leitão Filho, Sonia Maria Faresin, Ricardo Gassmann Figueiredo, Andrea Antunes Cetlin, Lilian Serrasqueiro Ballini Caetano, José Baddini-Martinez","doi":"10.36416/1806-3756/e20240388","DOIUrl":"10.36416/1806-3756/e20240388","url":null,"abstract":"Objective: To evaluate the quality of ChatGPT answers to asthma-related questions, as assessed from the perspectives of asthma specialists and laypersons.Methods: Seven asthma-related questions were asked to ChatGPT (version 4) between May 3, 2024 and May 4, 2024. The questions were standardized with no memory of previous conversations to avoid bias. Six pulmonologists with extensive expertise in asthma acted as judges, independently assessing the quality and reproducibility of the answers from the perspectives of asthma specialists and laypersons. A Likert scale ranging from 1 to 4 was used, and the content validity coefficient was calculated to assess the level of agreement among the judges.Results: The evaluations showed variability in the quality of the answers provided by ChatGPT. From the perspective of asthma specialists, the scores ranged from 2 to 3, with greater divergence in questions 2, 3, and 5. From the perspective of laypersons, the content validity coefficient exceeded 0.80 for four of the seven questions, with most answers being correct despite a lack of significant depth.Conclusions: Although ChatGPT performed well in providing answers to laypersons, the answers that it provided to specialists were less accurate and superficial. Although AI has the potential to provide useful information to the public, it should not replace medical guidance. Critical analysis of AI-generated information remains essential for health care professionals and laypersons alike, especially for complex conditions such as asthma.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"51 3","pages":"e20240388"},"PeriodicalIF":3.0,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0