Jeadran Malagón-Rojas1, Yesith Toloza1, Alvaro J. Idrovo2, Jürg Niederbacher-Velazquez3
{"title":"Initial insights on vaping-associated illnesses in Colombia: evidence for action","authors":"Jeadran Malagón-Rojas1, Yesith Toloza1, Alvaro J. Idrovo2, Jürg Niederbacher-Velazquez3","doi":"10.36416/1806-3756/e20230130","DOIUrl":"https://doi.org/10.36416/1806-3756/e20230130","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135569588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose Daniel Gómez-Olivas1, Grace Oscullo1, Miguel Ángel Martínez-García1,2
{"title":"Idiopathic bronchiectasis. What are we talking about?","authors":"Jose Daniel Gómez-Olivas1, Grace Oscullo1, Miguel Ángel Martínez-García1,2","doi":"10.36416/1806-3756/e20230249","DOIUrl":"https://doi.org/10.36416/1806-3756/e20230249","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135728678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Questionnaires and risk scores: how to transform research projects into practical tools","authors":"Frederico Leon Arrabal Fernandes1","doi":"10.36416/1806-3756/e20230302","DOIUrl":"https://doi.org/10.36416/1806-3756/e20230302","url":null,"abstract":"","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135728565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Igor Magaton Ribas1, João Pedro Medeiros Gomes¹, Pedro Augusto Rosa Valadares¹, Lucas Santos Jardim¹, Mário Círio Nogueira¹, Cássia de Castro Martins Ferreira2, William Cossich Marcial de Farias3, Letícia de Castro Martins Ferreira1
{"title":"Effects of air temperature on the risk of death from COPD in major microregions in Brazil: a time series study","authors":"Igor Magaton Ribas1, João Pedro Medeiros Gomes¹, Pedro Augusto Rosa Valadares¹, Lucas Santos Jardim¹, Mário Círio Nogueira¹, Cássia de Castro Martins Ferreira2, William Cossich Marcial de Farias3, Letícia de Castro Martins Ferreira1","doi":"10.36416/1806-3756/e20220442","DOIUrl":"https://doi.org/10.36416/1806-3756/e20220442","url":null,"abstract":"Objective: To evaluate the association between the risk of death from COPD and air temperature events in ten major Brazilian microregions. Methods: This was a time series analysis of daily COPD deaths and daily mean air temperatures between 1996 and 2017. Using distributed nonlinear lag models, we estimated the cumulative relative risks of COPD mortality for four temperature percentiles (representing moderate and extreme cold and heat events) in relation to a minimum mortality temperature, with a lag of 21 days, in each microregion. Results: Significant associations were found between extreme air temperature events and the risk of death from COPD in the southern and southeastern microregions in Brazil. There was an association of extreme cold and an increased mortality risk in the following microregions: 36% (95% CI, 1.12-1.65), in Porto Alegre; 27% (95% CI, 1.03-1.58), in Curitiba; and 34% (95% CI, 1.19-1.52), in São Paulo; whereas moderate cold was associated with an increased risk of 20% (95% CI, 1.01-1.41), 33% (95% CI, 1.09-1.62), and 24% (95% CI, 1.12-1.38) in the same microregions, respectively. There was an increased COPD mortality risk in the São Paulo and Rio de Janeiro microregions: 17% (95% CI, 1.05-1.31) and 12% (95% CI, 1,02-1,23), respectively, due to moderate heat, and 23% (95% CI, 1,09-1,38) and 32% (95% CI, 1,15-1,50) due to extreme heat. Conclusions: Non-optimal air temperature events were associated with an increased risk of death from COPD in tropical and subtropical areas of Brazil.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136293961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Alberto Neder, Danilo Cortozi Berton, Denis E O'Donnell
{"title":"The role of the pulmonary function laboratory to assist in disease management: Asthma.","authors":"José Alberto Neder, Danilo Cortozi Berton, Denis E O'Donnell","doi":"10.36416/1806-3756/e20230236","DOIUrl":"10.36416/1806-3756/e20230236","url":null,"abstract":"Asthma is a heterogeneous, chronic airway inflammatory disease in which pulmonary function tests (PFTs) might provide valuable information for diagnosis, assessment of clinical control","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"49 4","pages":"e20230236"},"PeriodicalIF":2.7,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/e5/1806-3756-jbpneu-49-04-e20230236.PMC10578945.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41130811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of vaccination on COVID-19 hospitalizations and mortality.","authors":"Fábio Fernandes Dantas Filho, Karen Gomes D'Ávila, Denise Rossato Silva","doi":"10.36416/1806-3756/e20230254","DOIUrl":"10.36416/1806-3756/e20230254","url":null,"abstract":"1. Hospital de Clínicas de Porto Alegre, Porto Alegre (RS) Brasil. 2. Programa de Pós-Graduação em Ciências Pneumológicas, Universidade Federal do Rio Grande do Sul – UFRGS – Porto Alegre (RS) Brasil. 3. Faculdade de Medicina, Universidade do Vale do Rio dos Sinos – Unisinos – São Leopoldo (RS) Brasil. 4. Faculdade de Medicina, Universidade Federal do Rio Grande do Sul –UFRGS – Porto Alegre (RS) Brasil. COVID-19, caused by SARS-CoV-2, has spread worldwide since December of 2019, causing significant morbidity and mortality. As of July 26, 2023, a total of 768,560,727 cases of COVID-19 had been confirmed worldwide, including 6,952,522 deaths. In Brazil, from January 3, 2020 to July 26, 2023, there were 37,704,598 confirmed COVID-19 cases and 704,488 COVID-19 deaths reported to the WHO.(1)","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"49 4","pages":"e20230254"},"PeriodicalIF":2.7,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/00/1806-3756-jbpneu-49-04-e20230254.PMC10578934.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41178972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dealing with confounding in observational studies.","authors":"Cristiane Fumo-Dos-Santos, Juliana Carvalho Ferreira","doi":"10.36416/1806-3756/e20230281","DOIUrl":"10.36416/1806-3756/e20230281","url":null,"abstract":"it is a cause of the outcome, and it is not in the causal pathway between the main exposure and the outcome of interest. In B, obesity is a confounder in the relation between asthma and lung function since obesity may worsen asthma and may cause a reduction in lung function. Adjusting for obesity is advised in this scenario. In C, the model represents a mediation effect —obstructive sleep apnea may lead to cardiovascular disease (direct effect), but obstructive sleep apnea may also lead to high blood pressure, which causes cardiovascular disease (indirect effect). In this case, adjusting for high blood pressure is not appropriate","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"49 4","pages":"e20230281"},"PeriodicalIF":2.7,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/85/1806-3756-jbpneu-49-04-e20230281.PMC10578949.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41127847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leonardo Meira de Faria, Vandack Nobre, Letícia Ribeiro de Oliveira Guardão, Camila Magalhães Souza, Amanda Damasceno de Souza, Deborah Dos Reis Estrella, Bruno Porto Pessoa, Ricardo Amorim Corrêa
{"title":"Factors associated with pulmonary infection in kidney and kidney-pancreas transplant recipients: a case-control study.","authors":"Leonardo Meira de Faria, Vandack Nobre, Letícia Ribeiro de Oliveira Guardão, Camila Magalhães Souza, Amanda Damasceno de Souza, Deborah Dos Reis Estrella, Bruno Porto Pessoa, Ricardo Amorim Corrêa","doi":"10.36416/1806-3756/e20220419","DOIUrl":"10.36416/1806-3756/e20220419","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the etiology of and factors associated with pulmonary infection in kidney and kidney-pancreas transplant recipients.</p><p><strong>Methods: </strong>This was a single-center case-control study conducted between December of 2017 and March of 2020 at a referral center for kidney transplantation in the city of Belo Horizonte, Brazil. The case:control ratio was 1:1.8. Cases included kidney or kidney-pancreas transplant recipients hospitalized with pulmonary infection. Controls included kidney or kidney-pancreas transplant recipients without pulmonary infection and matched to cases for sex, age group, and donor type (living or deceased).</p><p><strong>Results: </strong>A total of 197 patients were included in the study. Of those, 70 were cases and 127 were controls. The mean age was 55 years (for cases) and 53 years (for controls), with a predominance of males. Corticosteroid use, bronchiectasis, and being overweight were associated with pulmonary infection risk in the multivariate logistic regression model. The most common etiologic agent of infection was cytomegalovirus (in 14.3% of the cases), followed by Mycobacterium tuberculosis (in 10%), Histoplasma capsulatum (in 7.1%), and Pseudomonas aeruginosa (in 7.1%).</p><p><strong>Conclusions: </strong>Corticosteroid use, bronchiectasis, and being overweight appear to be risk factors for pulmonary infection in kidney/kidney-pancreas transplant recipients, endemic mycoses being prevalent in this population. Appropriate planning and follow-up play an important role in identifying kidney and kidney-pancreas transplant recipients at risk of pulmonary infection.</p>","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"49 4","pages":"e20220419"},"PeriodicalIF":2.9,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/0f/1806-3756-jbpneu-49-04-e20220419.PMC10578948.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41132232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Paula Santos, Fernanda Carvalho de Queiroz Mello
{"title":"\"Post-tuberculosis financial disease\"-we need to face it to eliminate tuberculosis.","authors":"Ana Paula Santos, Fernanda Carvalho de Queiroz Mello","doi":"10.36416/1806-3756/e20230253","DOIUrl":"10.36416/1806-3756/e20230253","url":null,"abstract":"1. Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro (RJ) Brasil. 2. Instituto de Doenças do Tórax, Universidade Federal do Rio de Janeiro, Rio de Janeiro (RJ) Brasil. In the study by Loureiro et al.,(1) published in this issue of the Jornal Brasileiro de Pneumologia, the authors studied the economic burden on the household during the follow-up of patients after tuberculosis diagnosis and treatment in five Brazilian capitals. They concluded that “participants incurred economic losses in the pre-diagnosis period and severe loss of income in the post-diagnosis period,”, which resulted in unemployment and social sequelae caused by tuberculosis.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"49 4","pages":"e20230253"},"PeriodicalIF":2.7,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/31/99/1806-3756-jbpneu-49-04-e20230253.PMC10578944.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41132231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcella M Musumeci, Bruno Valle Pinheiro, Luciana Dias Chiavegato, Danielle Silva Almeida Phillip, Flavia R Machado, Fabrício Freires, Osvaldo Shigueomi Beppu, Jaquelina Sonoe Ota Arakaki, Roberta Pulcheri Ramos
{"title":"Predictors of prolonged ventilator weaning and mortality in critically ill patients with COVID-19.","authors":"Marcella M Musumeci, Bruno Valle Pinheiro, Luciana Dias Chiavegato, Danielle Silva Almeida Phillip, Flavia R Machado, Fabrício Freires, Osvaldo Shigueomi Beppu, Jaquelina Sonoe Ota Arakaki, Roberta Pulcheri Ramos","doi":"10.36416/1806-3756/e20230131","DOIUrl":"10.36416/1806-3756/e20230131","url":null,"abstract":"<p><strong>Objective: </strong>To identify factors associated with prolonged weaning and mortality in critically ill COVID-19 patients admitted to ICUs and under invasive mechanical ventilation.</p><p><strong>Methods: </strong>Between March of 2020 and July of 2021, we retrospectively recorded clinical and ventilatory characteristics of critically ill COVID-19 patients from the day of intubation to the outcome. We classified the patients regarding the weaning period in accordance with established criteria. A logistic regression analysis was performed to identify variables associated with prolonged weaning and mortality.</p><p><strong>Results: </strong>The study involved 303 patients, 100 of whom (33.0%) had a prolonged weaning period. Most of the patients were male (69.6%), 136 (44.8%) had more than 50% of pulmonary involvement on chest CT, and 93 (30.6%) had severe ARDS. Within the prolonged weaning group, 62% died within 60 days. Multivariate analysis revealed that lung involvement greater than 50% on CT and delay from intubation to the first separation attempt from mechanical ventilation were significantly associated with prolonged weaning, whereas age and prolonged weaning were significantly associated with mortality.</p><p><strong>Conclusions: </strong>Prolonged weaning can be used as a milestone in predicting mortality in critically ill COVID-19 patients. Lung involvement greater than 50% on CT and delay from intubation to the first separation attempt from mechanical ventilation were identified as significant predictors of prolonged weaning. These results might provide valuable information for healthcare professionals when making clinical decisions regarding the management of critically ill COVID-19 patients who are on mechanical ventilation.</p>","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"49 4","pages":"e20230131"},"PeriodicalIF":2.9,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7c/d1/1806-3756-jbpneu-49-04-e20230131.PMC10578941.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41130726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}