发布求助
文献互助 智能选刊 最新文献

JACC: Basic to Translational Science最新文献

筛选
英文 中文
Empagliflozin in Acute Myocardial Infarction Reduces No-Reflow and Preserves Cardiac Function by Preventing Endothelial Damage 恩格列净治疗急性心肌梗死可通过预防内皮损伤减少无回流并保护心功能
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/j.jacbts.2024.08.003
Panagiota Efstathia Nikolaou PhD , Lara S.F. Konijnenberg MD, PhD , Ioannis V. Kostopoulos PhD , Marios Miliotis PhD , Nikolaos Mylonas MSc , Anastasios Georgoulis PhD , George Pavlidis MD, PhD , Carolien T.A. Kuster Msc , Vince P.A. van Reijmersdal Msc , Tom T.J. Luiken Msc , Anna Agapaki PhD , Rona Roverts PhD , Nikolaos Orologas PhD , Dimitris Grigoriadis PhD , Gaëtan Pallot PhD , Pierre Boucher MSc , Nikolaos Kostomitsopoulos PhD , Michael Paul Pieper PhD , Stéphane Germain PhD , Yannis Loukas PhD , Ioanna Andreadou PhD
{"title":"Empagliflozin in Acute Myocardial Infarction Reduces No-Reflow and Preserves Cardiac Function by Preventing Endothelial Damage","authors":"Panagiota Efstathia Nikolaou PhD ,&nbsp;Lara S.F. Konijnenberg MD, PhD ,&nbsp;Ioannis V. Kostopoulos PhD ,&nbsp;Marios Miliotis PhD ,&nbsp;Nikolaos Mylonas MSc ,&nbsp;Anastasios Georgoulis PhD ,&nbsp;George Pavlidis MD, PhD ,&nbsp;Carolien T.A. Kuster Msc ,&nbsp;Vince P.A. van Reijmersdal Msc ,&nbsp;Tom T.J. Luiken Msc ,&nbsp;Anna Agapaki PhD ,&nbsp;Rona Roverts PhD ,&nbsp;Nikolaos Orologas PhD ,&nbsp;Dimitris Grigoriadis PhD ,&nbsp;Gaëtan Pallot PhD ,&nbsp;Pierre Boucher MSc ,&nbsp;Nikolaos Kostomitsopoulos PhD ,&nbsp;Michael Paul Pieper PhD ,&nbsp;Stéphane Germain PhD ,&nbsp;Yannis Loukas PhD ,&nbsp;Ioanna Andreadou PhD","doi":"10.1016/j.jacbts.2024.08.003","DOIUrl":"10.1016/j.jacbts.2024.08.003","url":null,"abstract":"<div><div>Empagliflozin treatment before acute myocardial infarction mainly targets the endothelial cell transcriptome. Empagliflozin treatment before and after myocardial infarction decreased no reflow and microvascular injury, leading to reduced infiltration of inflammatory cells, reduced infarct size, and improved cardiac function in mice. In diabetic patients receiving empagliflozin after myocardial infarction, perfused boundary region, flow-mediated dilation, and global longitudinal strain were improved.</div></div>","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"10 1","pages":"Pages 43-61"},"PeriodicalIF":8.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142207141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Full Issue PDF
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/S2452-302X(24)00480-7
{"title":"Full Issue PDF","authors":"","doi":"10.1016/S2452-302X(24)00480-7","DOIUrl":"10.1016/S2452-302X(24)00480-7","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"10 1","pages":"Pages I-CXXXII"},"PeriodicalIF":8.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/j.jacbts.2024.09.006
Jean W. Wassenaar MD PhD , C. Duncan Smart MD PhD , Daniel J. Fehrenbach PhD , Vineet Agrawal MD PhD , Matthew M. Dungan BS , Niki L. Fortune , Lin Zhong MD PhD , Anna R. Hemnes MD , R. Stokes Peebles Jr. MD , Francis J. Miller Jr. MD , Amanda C. Doran MD PhD , Meena S. Madhur MD PhD
{"title":"Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease","authors":"Jean W. Wassenaar MD PhD ,&nbsp;C. Duncan Smart MD PhD ,&nbsp;Daniel J. Fehrenbach PhD ,&nbsp;Vineet Agrawal MD PhD ,&nbsp;Matthew M. Dungan BS ,&nbsp;Niki L. Fortune ,&nbsp;Lin Zhong MD PhD ,&nbsp;Anna R. Hemnes MD ,&nbsp;R. Stokes Peebles Jr. MD ,&nbsp;Francis J. Miller Jr. MD ,&nbsp;Amanda C. Doran MD PhD ,&nbsp;Meena S. Madhur MD PhD","doi":"10.1016/j.jacbts.2024.09.006","DOIUrl":"10.1016/j.jacbts.2024.09.006","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"10 1","pages":"Pages 107-109"},"PeriodicalIF":8.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143165280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Miniature Implantable Left Atrial/Ventricular Pump to Treat Symptoms of Heart Failure With Preserved Ejection Fraction 微型植入左心房/心室泵治疗保留射血分数的心力衰竭症状：一种新型装置治疗方法
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.10.004
Andrew J. Malone PhD, MSc , Kurdo Araz MSc, BMSc , Jemil Saidi MSc, BSc , Donald Hickey MDes , Darragh Colgan PhD, MBA, BEng , Aamir Hameed MBBS, MD
{"title":"Miniature Implantable Left Atrial/Ventricular Pump to Treat Symptoms of Heart Failure With Preserved Ejection Fraction","authors":"Andrew J. Malone PhD, MSc ,&nbsp;Kurdo Araz MSc, BMSc ,&nbsp;Jemil Saidi MSc, BSc ,&nbsp;Donald Hickey MDes ,&nbsp;Darragh Colgan PhD, MBA, BEng ,&nbsp;Aamir Hameed MBBS, MD","doi":"10.1016/j.jacbts.2024.10.004","DOIUrl":"10.1016/j.jacbts.2024.10.004","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages 1385-1387"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semaglutide Reduces Cardiomyocyte Size and Cardiac Mass in Lean and Obese Mice 西马鲁肽减少瘦和肥胖小鼠心肌细胞大小和心脏质量。
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.07.006
Matthew D. Martens PhD , Yasser Abuetabh PhD , Mya A. Schmidt BSc , Matthieu C.P. Zolondek BSc , Heidi L. Silver , Jody L. Levasseur , Mourad Ferdaoussi PhD , Jason R.B. Dyck PhD
{"title":"Semaglutide Reduces Cardiomyocyte Size and Cardiac Mass in Lean and Obese Mice","authors":"Matthew D. Martens PhD ,&nbsp;Yasser Abuetabh PhD ,&nbsp;Mya A. Schmidt BSc ,&nbsp;Matthieu C.P. Zolondek BSc ,&nbsp;Heidi L. Silver ,&nbsp;Jody L. Levasseur ,&nbsp;Mourad Ferdaoussi PhD ,&nbsp;Jason R.B. Dyck PhD","doi":"10.1016/j.jacbts.2024.07.006","DOIUrl":"10.1016/j.jacbts.2024.07.006","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages 1429-1431"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Where Comity in Science Goes to Die 科学中的团结走向消亡。
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.11.003
Douglas L. Mann MD (Editor-in-Chief, JACC: Basic to Translational Science)
{"title":"Where Comity in Science Goes to Die","authors":"Douglas L. Mann MD (Editor-in-Chief, JACC: Basic to Translational Science)","doi":"10.1016/j.jacbts.2024.11.003","DOIUrl":"10.1016/j.jacbts.2024.11.003","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages 1440-1441"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF 运动疗法可拯救心脏代谢性HFpEF的骨骼肌功能障碍和运动不耐受。
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.07.009
Heather Quiriarte MS , Robert C. Noland PhD , James E. Stampley PhD , Gregory Davis MS , Zhen Li PhD , Eunhan Cho PhD , Youyoung Kim MS , Jake Doiron BS , Guillaume Spielmann PhD , Sujoy Ghosh PhD , Sanjiv J. Shah MD , Brian A. Irving PhD , David J. Lefer PhD , Timothy D. Allerton PhD
{"title":"Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF","authors":"Heather Quiriarte MS ,&nbsp;Robert C. Noland PhD ,&nbsp;James E. Stampley PhD ,&nbsp;Gregory Davis MS ,&nbsp;Zhen Li PhD ,&nbsp;Eunhan Cho PhD ,&nbsp;Youyoung Kim MS ,&nbsp;Jake Doiron BS ,&nbsp;Guillaume Spielmann PhD ,&nbsp;Sujoy Ghosh PhD ,&nbsp;Sanjiv J. Shah MD ,&nbsp;Brian A. Irving PhD ,&nbsp;David J. Lefer PhD ,&nbsp;Timothy D. Allerton PhD","doi":"10.1016/j.jacbts.2024.07.009","DOIUrl":"10.1016/j.jacbts.2024.07.009","url":null,"abstract":"<div><div>Exercise intolerance, a hallmark of heart failure with preserved ejection fraction (HFpEF) exacerbated by obesity, involves unclear mechanisms related to skeletal muscle metabolism. In a “2-hit” model of HFpEF, we investigated the ability of exercise therapy (voluntary wheel running) to reverse skeletal muscle dysfunction and exercise intolerance. Using state-of-the-art metabolic cages and a multiomic approach, we demonstrate exercise can rescue dysfunctional skeletal muscle lipid and branched-chain amino acid oxidation and restore exercise capacity in mice with cardiometabolic HFpEF. These results underscore the importance of skeletal muscle metabolism to improve exercise intolerance in HFpEF.</div></div>","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages 1409-1425"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-Time Revolution 实时革命：自适应TMVR解决方案。
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.09.013
Shira Burg DVM, PhD, Yulia Cladco MD
{"title":"Real-Time Revolution","authors":"Shira Burg DVM, PhD,&nbsp;Yulia Cladco MD","doi":"10.1016/j.jacbts.2024.09.013","DOIUrl":"10.1016/j.jacbts.2024.09.013","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages 1379-1381"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Full Issue PDF
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/S2452-302X(24)00429-7
{"title":"Full Issue PDF","authors":"","doi":"10.1016/S2452-302X(24)00429-7","DOIUrl":"10.1016/S2452-302X(24)00429-7","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages I-LXVIII"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143162821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TriClover 三尖瓣：经导管修复三尖瓣的新技术，高效、适应症广。
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.10.003
Michele De Bonis MD , Maurizio Taramasso MD, PhD , Marco Gard MA , Ottavio R. Alfieri MD
{"title":"TriClover","authors":"Michele De Bonis MD ,&nbsp;Maurizio Taramasso MD, PhD ,&nbsp;Marco Gard MA ,&nbsp;Ottavio R. Alfieri MD","doi":"10.1016/j.jacbts.2024.10.003","DOIUrl":"10.1016/j.jacbts.2024.10.003","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages 1382-1384"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信