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Journal Der Deutschen Dermatologischen Gesellschaft最新文献

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In vivo and ex vivo sonographic evaluation of tumor margins during micrographic-controlled surgery: a promising new tool in dermato-oncology? 显微摄影控制手术中肿瘤边缘的体内和体外超声评估：一种有前途的皮肤肿瘤学新工具？
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-07-02 DOI: 10.1111/ddg.15827
Diana Crisan, Ximena Wortsman, Fernando Alfageme, Karin Scharffetter-Kochanek, Maria Crisan, Lukas Bernhard, Evelyne Tarnowietzki, Lars Alexander Schneider, Monika-H Schmid-Wendtner
{"title":"In vivo and ex vivo sonographic evaluation of tumor margins during micrographic-controlled surgery: a promising new tool in dermato-oncology?","authors":"Diana Crisan, Ximena Wortsman, Fernando Alfageme, Karin Scharffetter-Kochanek, Maria Crisan, Lukas Bernhard, Evelyne Tarnowietzki, Lars Alexander Schneider, Monika-H Schmid-Wendtner","doi":"10.1111/ddg.15827","DOIUrl":"https://doi.org/10.1111/ddg.15827","url":null,"abstract":"<p><strong>Background and objectives: </strong>The current research examined the In vivo and ex vivo use of high-frequency ultrasound (HFUS) during micrographic-controlled surgery (MCS) of non-melanoma skin cancer (NMSC) of the head-and-face area, particularly the perioperative surgical margin assessment for potential reduction in surgical steps and patients' hospitalization time.</p><p><strong>Patients and methods: </strong>Pre-operative in vivo and ex vivo sonographies of 136 NMSCs from 111 patients were evaluated retrospectively for tumor margin assessment during MCS by an experienced dermatosurgeon, while the specimens were independently assessed by a histopathologist.</p><p><strong>Results: </strong>Our ex-vivo tumor margin assessment showed a specificity of >98% for squamous cell and basal cell carcinoma, with only five false-negative and two false-positive results, when compared to histopathology. HFUS correctly identified tumor-free margins in 89% of investigated lesions after first resection, as well as eight incomplete excisions (6%) in which a re-excision was performed and tumor residues were detected histologically. Overall, HFUS showed a very high accuracy in detecting both cancer-free margins and remaining tumor residues.</p><p><strong>Conclusions: </strong>HFUS is a highly accurate method for rapidly assessing tumor margins during MCS of NMSC of highly esthetic areas, having the potential to significantly reduce surgical steps and hospitalization time in dermatosurgical patients, improving the quality of healthcare.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipschütz ulcer: A case series of non-sexually acquired genital ulceration in young women. lipsch<s:1>茨溃疡：一例年轻女性非性获得性生殖器溃疡。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-07-02 DOI: 10.1111/ddg.15815
Julian Steininger, Michael Eckert, Sophia Lehr, Susanne Abraham, Stefan Beissert, Claudia Günther
{"title":"Lipschütz ulcer: A case series of non-sexually acquired genital ulceration in young women.","authors":"Julian Steininger, Michael Eckert, Sophia Lehr, Susanne Abraham, Stefan Beissert, Claudia Günther","doi":"10.1111/ddg.15815","DOIUrl":"https://doi.org/10.1111/ddg.15815","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of juvenile bullous pemphigoid with lebrikizumab. lebrikizumab治疗幼年大疱性类天疱疮。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-07-02 DOI: 10.1111/ddg.15831
Marcel Wittenberg, Farzan Solimani, Amrei Dilling, Rawan Snobar, Kamran Ghoreschi, Marisa Klemp, Kerstin Kusch
{"title":"Treatment of juvenile bullous pemphigoid with lebrikizumab.","authors":"Marcel Wittenberg, Farzan Solimani, Amrei Dilling, Rawan Snobar, Kamran Ghoreschi, Marisa Klemp, Kerstin Kusch","doi":"10.1111/ddg.15831","DOIUrl":"https://doi.org/10.1111/ddg.15831","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
X-linked dominant chondrodysplasia punctata (CDPX2): A rare case of male mosaicism with atypical dermatological manifestations. x连锁显性点状软骨发育不良（CDPX2）：一个罕见的男性嵌合性病例，具有不典型的皮肤病表现。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-06-29 DOI: 10.1111/ddg.15772
Lluís Corbella-Bagot, Marta Ivars, Luisa Montenegro, Dídac Casas-Alba, Judith Armstrong Morón, Jonathan Olival, Eulàlia Baselga Torres
{"title":"X-linked dominant chondrodysplasia punctata (CDPX2): A rare case of male mosaicism with atypical dermatological manifestations.","authors":"Lluís Corbella-Bagot, Marta Ivars, Luisa Montenegro, Dídac Casas-Alba, Judith Armstrong Morón, Jonathan Olival, Eulàlia Baselga Torres","doi":"10.1111/ddg.15772","DOIUrl":"https://doi.org/10.1111/ddg.15772","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Annular erythematous plaques with tense blisters on the extremities. 四肢环状红斑斑块伴紧张的水泡。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-06-29 DOI: 10.1111/ddg.15811
Chunxia Zhao, Yuwei Zhang, Lei Wang
{"title":"Annular erythematous plaques with tense blisters on the extremities.","authors":"Chunxia Zhao, Yuwei Zhang, Lei Wang","doi":"10.1111/ddg.15811","DOIUrl":"https://doi.org/10.1111/ddg.15811","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcomes of chlormethine gel in mycosis fungoides affecting "sensitive" areas: A retrospective case series. 氯甲基凝胶治疗影响“敏感”区域的蕈样真菌病的临床结果：回顾性病例系列。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-06-29 DOI: 10.1111/ddg.15797
Gianluca Tavoletti, Gianluca Avallone, Pamela Vezzoli, Paolo Sena, Angelo V Marzano, Emilio Berti, Silvia Alberti-Violetti
{"title":"Clinical outcomes of chlormethine gel in mycosis fungoides affecting \"sensitive\" areas: A retrospective case series.","authors":"Gianluca Tavoletti, Gianluca Avallone, Pamela Vezzoli, Paolo Sena, Angelo V Marzano, Emilio Berti, Silvia Alberti-Violetti","doi":"10.1111/ddg.15797","DOIUrl":"https://doi.org/10.1111/ddg.15797","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The diagnosis of early-stage mycosis fungoides: Views held by experts and non-experts in cutaneous lymphoma. 早期蕈样真菌病的诊断：皮肤淋巴瘤专家与非专家的观点。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-06-29 DOI: 10.1111/ddg.15799
Paula Beatty, Kevin Molloy, Stefanie Porkert, Megan Power Foley, Anne-Marie Tobin, Franz Trautinger, Julia Scarisbrick, Constanze Jonak
{"title":"The diagnosis of early-stage mycosis fungoides: Views held by experts and non-experts in cutaneous lymphoma.","authors":"Paula Beatty, Kevin Molloy, Stefanie Porkert, Megan Power Foley, Anne-Marie Tobin, Franz Trautinger, Julia Scarisbrick, Constanze Jonak","doi":"10.1111/ddg.15799","DOIUrl":"https://doi.org/10.1111/ddg.15799","url":null,"abstract":"<p><strong>Background and objectives: </strong>Mycosis fungoides (MF) accounts for the majority of cutaneous lymphomas (CL). There is a documented delay in the diagnosis of early-stage MF. However, its timely diagnosis is paramount to avoid potentially harmful therapies and undue patient distress. The aim of this study was to examine and compare the views held by both specialists and non-specialists in CL regarding the diagnosis of early-stage MF, to identify clinical needs.</p><p><strong>Methods: </strong>Two distinct questionnaires were distributed to physicians, who either have a potential or no special interest in CL (non-specialists), or who have a special interest in CL (specialists) and who were identified by participation in the PROCLIPI (PROspective Cutaneous Lymphoma International Prognostic Index) study.</p><p><strong>Results: </strong>Survey results were received from 382 participants, 86 specialists, and 296 non-specialists. In total, 82% of respondents held the view that the diagnosis of early-stage MF is delayed. The frequent misclassification of MF as a benign inflammatory dermatosis was identified as the most important contributing factor.</p><p><strong>Conclusions: </strong>Non-specialists assume that a delayed diagnosis impairs therapeutic efficacy and prognosis in MF, while specialists primarily suspect negative effects on patients' health-related quality of life. Our study reveals an unmet need to promote education and increase awareness among dermatologists regarding the impact of early-stage MF on patient management.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Type I IFN receptor blockade by anifrolumab reduces cutaneous lupus in monogenic SLE. 单克隆抗体阻断I型IFN受体可减少单基因SLE患者的皮肤红斑狼疮。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-06-26 DOI: 10.1111/ddg.15806
Julian Steininger, Christine Wolf, Min Ae Lee-Kirsch, Claudia Günther
{"title":"Type I IFN receptor blockade by anifrolumab reduces cutaneous lupus in monogenic SLE.","authors":"Julian Steininger, Christine Wolf, Min Ae Lee-Kirsch, Claudia Günther","doi":"10.1111/ddg.15806","DOIUrl":"https://doi.org/10.1111/ddg.15806","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generalized pustular psoriasis in a patient with asthma following dupilumab and tezepelumab therapy. dupilumab和tezepelumab治疗后哮喘患者的广泛性脓疱性牛皮癣。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-06-25 DOI: 10.1111/ddg.15800
Misaki Kawakami, Hana Takeshita, Atsushi Oda, Takeshi Namiki, Keiko Komatsuzaki, Yasunari Miyazaki, Naoko Okiyama
{"title":"Generalized pustular psoriasis in a patient with asthma following dupilumab and tezepelumab therapy.","authors":"Misaki Kawakami, Hana Takeshita, Atsushi Oda, Takeshi Namiki, Keiko Komatsuzaki, Yasunari Miyazaki, Naoko Okiyama","doi":"10.1111/ddg.15800","DOIUrl":"https://doi.org/10.1111/ddg.15800","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical propranolol and sirolimus in Pentravan: A promising non-systemic approach for Kaposi's sarcoma management. 局部普萘洛尔和西罗莫司在戊特拉凡：一个有前途的非系统性方法卡波西肉瘤的管理。
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-06-25 DOI: 10.1111/ddg.15822
Caterina Mariarosaria Giorgio, Vittorio Tancredi, Gaetano Licata, Giuseppe Argenziano, Eugenia Veronica Di Brizzi
{"title":"Topical propranolol and sirolimus in Pentravan: A promising non-systemic approach for Kaposi's sarcoma management.","authors":"Caterina Mariarosaria Giorgio, Vittorio Tancredi, Gaetano Licata, Giuseppe Argenziano, Eugenia Veronica Di Brizzi","doi":"10.1111/ddg.15822","DOIUrl":"https://doi.org/10.1111/ddg.15822","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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