Journal Der Deutschen Dermatologischen Gesellschaft最新文献

Dupilumab for the treatment of eczema molluscatum: A pediatric case report and systematic literature review. 杜匹单抗治疗软性湿疹：一个儿科病例报告和系统文献综述。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-08 DOI: 10.1111/ddg.70176

Patrick E Obermeier, Uda Puzich, Annika Brinkmann, Livia Schrick, Alexandra Mühlendyck

{"title":"Dupilumab for the treatment of eczema molluscatum: A pediatric case report and systematic literature review.","authors":"Patrick E Obermeier, Uda Puzich, Annika Brinkmann, Livia Schrick, Alexandra Mühlendyck","doi":"10.1111/ddg.70176","DOIUrl":"https://doi.org/10.1111/ddg.70176","url":null,"abstract":"Atopic dermatitis (AD) may be complicated by disseminated molluscum contagiosum virus (MOCV) infection, known as eczema molluscatum (EM), particularly in children. Topical treatments are not always effective, and although modern systemic immunomodulatory therapies for AD, including use in early childhood, are available, their impact on co-occurring MCV infection is not well documented. We present a 4-year-old child with severe EM that was refractory to conventional topical therapy. She was treated with dupilumab (300 mg subcutaneously every four weeks), which led to a rapid resolution of symptoms and clinical clearance of MOCV-1 infection without adverse events. To contextualize our findings, we performed a systematic literature review, including PubMed, ScienceDirect, Scopus, and Google Scholar, to identify published case descriptions of dupilumab use with co-occurring MOCV infection (PROSPERO ID CRD420251106639). We identified a total of six publications reporting on nine adult patients (mean age: 40 years, range: 21-58 years, 8/9 male). In five of these patients, EM temporarily flared up before resolution. The present report is the first of a child. Our findings, along with existing reports, suggest that dupilumab may be a safe and effective treatment option for AD patients with MOCV infection. Prospective evaluation using standardized outcome measures is warranted.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitization profiles in patients with wheat-dependent exercise-induced anaphylaxis: practical aspects for allergy workup. 小麦依赖性运动诱发过敏性反应患者的致敏概况：过敏检查的实际方面。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-08 DOI: 10.1111/ddg.70198

Enna M Schwarze, Carolin C Albers, Randolf Brehler, Mathias Sulk

{"title":"Sensitization profiles in patients with wheat-dependent exercise-induced anaphylaxis: practical aspects for allergy workup.","authors":"Enna M Schwarze, Carolin C Albers, Randolf Brehler, Mathias Sulk","doi":"10.1111/ddg.70198","DOIUrl":"https://doi.org/10.1111/ddg.70198","url":null,"abstract":"Background: Wheat-dependent exercise-induced anaphylaxis (WDEIA) occurs after ingestion of wheat/gluten in the presence of various cofactors. Here, we characterized the sensitization spectrum to various wheat flours, as revealed by skin prick test (SPT) and specific IgE (sIgE) against wheat flour, gluten, and various wheat components. The findings were correlated with medical history and oral food challenge (OFC) outcomes in patients with suspected WDEIA.Patients and methods: Retrospectively, 60 patients with specific immunoglobulin E (sIgE) against ω5-gliadin and a history of anaphylaxis after wheat ingestion were analyzed.Results: WDEIA was confirmed after OFC (38/60) in approximately 75 %. With SPT, increased wheal diameters for wheat flours were observed in patients with a history of severe anaphylaxis when compared to patients with milder symptoms of anaphylaxis. Patients with OFC-confirmed WDEIA showed higher SPT wheal diameters for gluten (when compared to patients with negative OFC). OFC outcomes could not be predicted by sIgEs against various wheat components; however, in a subgroup of patients, the values of sIgE against ω5-gliadin and gluten tended to be higher with greater anaphylaxis severity grade.Conclusions: Thorough medical history taking is crucial for patients with a history of anaphylaxis. Although SPT and sIgE can guide diagnosis, only OFC can confirm the diagnosis of WDEIA.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dupilumab-Induced Psoriasis in a Patient with Bullous Pemphigoid. 大疱性类天疱疮患者的dupilumab诱导牛皮癣。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-08 DOI: 10.1111/ddg.70397

Nina Matthes, Julian Kött, Finn Abeck, Inga Hansen-Abeck, Jana Bertels, Nina Booken, Stefan W Schneider

引用次数: 0

Be aware of MPDCP! Pruritic skin lesions as signpost for underlying myeloid leukemia. 注意MPDCP！瘙痒性皮肤病变作为潜在髓性白血病的标志。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-08 DOI: 10.1111/ddg.70361

Uwe Hillen, Christina Mitteldorf, Leo Schaerer, Ronny Nienhold, Cornelia Pfranger-Deubelbeiss, Emel Tuerkay, Lisa Eisert, Werner Kempf

引用次数: 0

Jacquet Erosive Dermatitis in a Child with DOCK8 Mutation. DOCK8突变儿童雅克糜烂性皮炎

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-08 DOI: 10.1111/ddg.70327

Tubanur Çetinarslan, Göksu Dalgıç, Pınar Şahin, Gülcihan Özek, Neslihan Edeer Karaca, Serap Aksoylar, Peyker Temiz, Coşkun Ekemen, Aylin Türel Ermertcan, Regina Fölster-Holst

引用次数: 0

Scrotal squamous cell carcinoma: Two HPV-negative cases with probable UV- induced pathogenesis. 阴囊鳞状细胞癌：2例hpv阴性，可能由紫外线诱发发病。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-06 DOI: 10.1111/ddg.70348

Daniel Craus, Ulrike Wieland, Steffi Silling, Julia Hyun, Milan Vidakovic, Frank Oellig, Alexander Kreuter, Valentina Laura Müller

引用次数: 0

Treatment of advanced cutaneous squamous cell carcinoma with cemiplimab in elderly multimorbid patients - a case series. 西米单抗治疗老年多病患者的晚期皮肤鳞状细胞癌-一个病例系列。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-06 DOI: 10.1111/ddg.70312x

Patryk Porebski, Katharina Amschler, Michael P Schön, Kai-Martin Thoms

引用次数: 0

S3 guideline diagnostics and therapy in alopecia areata - Part 2: Therapy, psychosocial and cosmetic support. S3指南斑秃的诊断和治疗。第2部分：治疗、社会心理和美容支持。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-04 DOI: 10.1111/ddg.70130x

Ulrike Blume-Peytavi, Andria Constantinou, Tsenka Tomova-Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn

{"title":"S3 guideline diagnostics and therapy in alopecia areata - Part 2: Therapy, psychosocial and cosmetic support.","authors":"Ulrike Blume-Peytavi, Andria Constantinou, Tsenka Tomova-Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn","doi":"10.1111/ddg.70130x","DOIUrl":"https://doi.org/10.1111/ddg.70130x","url":null,"abstract":"This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and prognostic factors. The application of corticosteroids is the only topical intervention with a high level of recommendation. All other topical agents that can be offered for the treatment of AA have a low level of recommendation, whereby the recommendation levels for the individual topical agents vary in the age groups of children, adolescents and adults. Of the active substances for systemic treatment of AA, only systemic corticosteroids and Janus kinase inhibitors (JAK) have a high level of recommendation, and they are restricted only to adults. Children and adolescents can be offered corticosteroids, methotrexate or JAK* (*with appropriate authorisation for the age group) for a severe form or higher. All other systemic agents should not be offered to children and adolescents. The expert group recommends that all patients with all forms of AA, regardless of age, should be informed about the possibilities of hair replacement and cosmetic options.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147815375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and safety of remibrutinib in chronic spontaneous urticaria: clinical experience. 瑞米鲁替尼治疗慢性自发性荨麻疹的疗效和安全性：临床经验。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-02 DOI: 10.1111/ddg.70288

Lucía Aguilar-González, Isabel María Villegas-Romero, Ricardo Patricio Román-Cheuque, David Jiménez-Gallo

引用次数: 0

Integrating social media into modern dermatology - a cross-sectional study. 将社交媒体融入现代皮肤病学——一项横断面研究。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2025-10-05 DOI: 10.1111/ddg.15911

Maximilian Lammer, Marina Wanner, Paul Bellmann, Magdalena Seidl-Philipp, Matthias Schmuth

{"title":"Integrating social media into modern dermatology - a cross-sectional study.","authors":"Maximilian Lammer, Marina Wanner, Paul Bellmann, Magdalena Seidl-Philipp, Matthias Schmuth","doi":"10.1111/ddg.15911","DOIUrl":"10.1111/ddg.15911","url":null,"abstract":"Background and objective: Social media is increasingly establishing itself as an important source of information for skin health. Although demand among users is high, very few dermatologists outside the Anglo-American region use these platforms to provide patient information, and the majority of content is provided by non-medical sources. This study investigated the influence of social media on skincare and preventive behavior among young adults, and the relevance of medically qualified content.Methods: An anonymized 34-item online questionnaire was distributed to 454 students at the University of Innsbruck, assessing social media usage, skincare routines, prevention behavior, and perception of dermatological content. Descriptive and inferential statistics (chi-square tests, p < 0.05) were applied.Results: A significant association was found between time spent on social media and perceived impact on personal skin health (p = 0.014). Participants exposed to dermatologist-created content were significantly more likely to follow a skincare routine (p < 0.001). The majority expressed a desire for more professionally qualified information.Conclusions: Social media offers significant potential for providing information about skin conditions and educating patients. A more comprehensive presence of content reviewed by medical professionals may help minimize the spread of misinformation and promote health education, especially among young users.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":"620-625"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13140118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0