Journal Der Deutschen Dermatologischen Gesellschaft最新文献

Atopic dermatitis and the outcomes of pregnancy and offspring: A nationwide population-based study in Taiwan. 特应性皮炎与妊娠和后代的影响：台湾一项全国性人口研究。

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-16 DOI: 10.1111/ddg.15555

Pei-Chun Weng, Jun-Fu Zhang, Chang-Fu Kuo, Yu-Huei Huang

{"title":"Atopic dermatitis and the outcomes of pregnancy and offspring: A nationwide population-based study in Taiwan.","authors":"Pei-Chun Weng, Jun-Fu Zhang, Chang-Fu Kuo, Yu-Huei Huang","doi":"10.1111/ddg.15555","DOIUrl":"https://doi.org/10.1111/ddg.15555","url":null,"abstract":"Background and objectives: Studies have identified increased risks of pregnancy complications in expectant mothers with atopic dermatitis (AD). However, the associations between maternal AD and adverse pregnancy or offspring outcomes in Asians remain unexplored. Our aim was to investigate the relationship between maternal AD and adverse pregnancy and offspring outcomes in Taiwan.Patients and methods: This retrospective cohort study collected data from Taiwan's National Health Insurance Research Database and the Taiwan Maternal and Child Health Database between 2003 and 2019. We recruited 15,495 AD mothers and 77,475 non-AD mothers, as well as 19,173 children born to AD mothers and 95,865 children born to non-AD mothers, using propensity score matching. Pregnancy and offspring outcomes were compared in the maternal and offspring cohorts, respectively.Results: AD mothers had higher risks of threatened abortion, preeclampsia/eclampsia, premature rupture of membranes, threatened preterm labor, fetal growth restriction, antepartum hemorrhage, postpartum hemorrhage, anemia, surgical complications, infections, pulmonary events, and renal events, with adjusted hazard ratios of 1.09-1.71. Children born to AD mothers had increased risks of AD, allergic rhinitis, asthma, alopecia areata, and attention deficit hyperactivity disorder, with adjusted hazard ratios of 1.05-2.29.Conclusions: There is a significant association between maternal AD and adverse pregnancy and offspring outcomes in Taiwan.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laser and light-based treatments for port-wine birthmarks - a systematic review and network meta-analysis.

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-12 DOI: 10.1111/ddg.15612

Lynhda Nguyen, Christina Sorbe, Gerhard Schoen, Stefan W Schneider, Katharina Herberger

{"title":"Laser and light-based treatments for port-wine birthmarks - a systematic review and network meta-analysis.","authors":"Lynhda Nguyen, Christina Sorbe, Gerhard Schoen, Stefan W Schneider, Katharina Herberger","doi":"10.1111/ddg.15612","DOIUrl":"https://doi.org/10.1111/ddg.15612","url":null,"abstract":"Port-wine birthmarks (PWB) are common vascular malformations in infants. Despite various laser and light-based treatments, comparative data on their effectiveness is limited. This study compares different treatments for PWB using a systematic review and network meta-analysis (NMA). We searched for randomized controlled trials (RCTs) and ongoing studies up to November 2023: Primary outcomes were patient satisfaction, investigator-assessed reduction in redness, and long-term adverse events (AEs). Risk of bias was assessed using the Cochrane Risk of Bias 2 Tool. We identified 27 RCTs for qualitative analysis and twelve RCTs for the NMA, covering 1033 observations, 19 treatments, and three sub-networks. Seven studies reported on patient satisfaction. Hemoporfin-mediated photodynamic therapy was more effective in lesion clearance than PDL but had the highest risk of AEs. The 755 nm alexandrite laser and the combination of 595 nm PDL + 1064 nm Nd:YAG also showed high AE risks. Treatment discontinuation rates due to AEs did not significantly differ. Most studies had unclear bias risks, mostly owing to insufficient reporting. This study is the first NMA comparing laser- and light-based therapies for PWB. Further well-designed studies are warranted to determine optimal methods and patient-influencing factors for individualized treatments.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Line-field confocal optical coherence tomography in lichen planopilaris and frontal fibrosing alopecia: A pilot study.

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-11 DOI: 10.1111/ddg.15591

Marie-Christine Nutz, Maximilian Deußing, Daniela Hartmann, Silvan Lange, Sonja Senner, Tamara Eyssele, Sandra Schuh, Lars E French, Julia Welzel, Elke C Sattler

{"title":"Line-field confocal optical coherence tomography in lichen planopilaris and frontal fibrosing alopecia: A pilot study.","authors":"Marie-Christine Nutz, Maximilian Deußing, Daniela Hartmann, Silvan Lange, Sonja Senner, Tamara Eyssele, Sandra Schuh, Lars E French, Julia Welzel, Elke C Sattler","doi":"10.1111/ddg.15591","DOIUrl":"https://doi.org/10.1111/ddg.15591","url":null,"abstract":"Background and objectives: Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are common causes of cicatricial alopecia. While several studies have demonstrated the usefulness of non-invasive imaging methods such as reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) for the diagnosis of scarring alopecia, this study aimed to identify characteristic features of cicatricial alopecia in LPP/FFA using line-field confocal OCT (LC-OCT).Patients and methods: Fifty-one patients (26 LPP, 24 FFA, 1 LPP and FFA) were prospectively analyzed with LC-OCT at three defined locations on the scalp: (1) scarring area = lesion, (2) scar-hair boundary = transition zone and (3) healthy area for the presence of the following pre-defined criteria: no hair follicles left, destructed hair follicles, dermal sclerosis, no rimming of the dermal papillae, epidermal and dermal inflammatory infiltrate, infundibular hyperkeratosis, dilated blood vessels, hypervascularization, melanophages, epidermal pigment incontinence.Results: Comparison of the transition zone with healthy control sites revealed the four main LC-OCT features in LPP/FFA: dermal sclerosis (100%), dermal inflammatory infiltrate (90.2%), infundibular hyperkeratosis (60.8%) and hypervascularization (76.5%).Conclusions: LC-OCT detects specific criteria of pathological changes in LPP/FFA around hair follicles in the epidermis and dermis and therefore can be used for further studies investigating scarring alopecia.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe overlap of morphea and lichen sclerosus after anti-PD-L1 immunotherapy in small cell lung cancer.

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-08 DOI: 10.1111/ddg.15599

Glenn Geidel, Anne Menz, Franziska M Grotenrath, Alessandra Rünger, Julian Kött, Stefan W Schneider, Christoffer Gebhardt, Nina Booken

引用次数: 0

Langfristige Remission und normale Schwangerschaft mit erfolgreicher Entbindung bei einer Patientin mit generalisierter pustulöser Psoriasis nach Spesolimab 一名全身性脓疱型银屑病患者使用斯派索利单抗后病情长期缓解、正常怀孕并顺利分娩

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-08 DOI: 10.1111/ddg.15571_g

Na Wang, Qing Yang, Weizhi Wu, Zhongxiang Shi, Hong Liu, Furen Zhang

引用次数: 0

Photodynamische Therapie in der Dermatologie: Bewährte und neue Indikationen

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-08 DOI: 10.1111/ddg.15464_g

Galina Balakirski, Percy Lehmann, Rolf-Markus Szeimies, Silke C. Hofmann

引用次数: 0

Zwei Fälle von Dupilumab-induzierter Vitiligo

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-08 DOI: 10.1111/ddg.15564_g

Ana Ferreirinha, Pedro Simões Farinha, Tomás Pessoa e Costa, Bruno Duarte

引用次数: 0

31. Jahrestagung der Arbeitsgemeinschaft Dermatologische Histologie (ADH)/Deutsche Gesellschaft für Dermatopathologie in Göttingen

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-08 DOI: 10.1111/ddg.15622_g

Christina Mitteldorf

引用次数: 0

Journal-Club

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-08 DOI: 10.1111/ddg.15614_g

Prof. Dr. Sigrid Karrer

引用次数: 0

Das blaue Gesicht

IF 5.5 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2024-12-08 DOI: 10.1111/ddg.15523_g

Franziska Jochims, Benjamin Klein, Jan C. Simon, Manfred Kunz

引用次数: 0