Journal Der Deutschen Dermatologischen Gesellschaft最新文献

{"title":"From Emperipolesis to Foam Cells: Sequential Xanthomatous Evolution in Cutaneous Rosai-Dorfman Disease.","authors":"Rika Yamamoto, Yasuaki Ikuno, Masahiro Yamada, Yasuhiro Maeda, Hiraku Kokubu, Akihiko Yamaguchi, Toshifumi Takahashi, Akiko Arakawa, Suzuko Moritani, Noriki Fujimoto","doi":"10.1111/ddg.70692","DOIUrl":"https://doi.org/10.1111/ddg.70692","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When to refuse cosmetic treatment - AI-decision support for differentiating melanocytic and non-melanocytic facial lesions.","authors":"Anastasia Sophie Vollmer, Julia Katharina Winkler, Ferdinand Toberer, Katharina Susanne Kommoss, Andreas Blum, Rainer Hofmann-Wellenhof, Wilhelm Stolz, Alexander Enk, Holger Andreas Haenssle","doi":"10.1111/ddg.70530","DOIUrl":"https://doi.org/10.1111/ddg.70530","url":null,"abstract":"<p><strong>Background: </strong>Flat pigmented skin lesions in chronically sun-exposed face and scalp areas present diagnostic challenges. Particularly, solar lentigo, pigmented actinic keratosis and lentigo maligna show overlapping features. Erroneous laser treatment of lentigo maligna for cosmetic reasons will inevitably delay diagnosis and compromise patient safety. This study assessed the performance of a market-approved convolutional neural network (CNN) versus dermatologists in differentiating melanocytic from non-melanocytic face and scalp lesions (FSL).</p><p><strong>Patients and methods: </strong>Cross-sectional two-level reader study using 100 histologically validated FSL (level I: dermoscopy only; level II: expanded case information). The primary outcome was the diagnostic accuracy of the CNN in comparison to 64 dermatologists reviewing expanded case information.</p><p><strong>Results: </strong>The CNN differentiated melanocytic and non-melanocytic FSL with an accuracy (95% CI) of 79.0% (69.7%-86.5%) and a ROC-AUC of 0.847 (0.772-0.923). Dermatologists reached a mean accuracy of 66.7% (64.7%-68.7%) at level I, which increased to 73.6% (72.1%-75.1%; p < 0.001) with expanded case information (level II). Compared with dermatologists at level II, the CNN demonstrated a significantly higher accuracy (79.0% vs. 73.6%; p < 0.001).</p><p><strong>Conclusion: </strong>Our findings suggest that a CNN trained to differentiate melanocytic from non-melanocytic FSL may improve clinicians' diagnostic accuracy when used as an AI-based decision support tool for determining whether cosmetic laser procedures could safely be performed.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of IL-17A and IL-23p19 Inhibitors on Psychiatric Outcomes and Inflammation in Psoriasis.","authors":"Ilknur Kıvanc Altunay, Aysenur Demir, Ahmet Kayaalti, Sena Inal Aptoula, Harbiye Dilek Canat, Burhan Engin, Yusuf Can Erkoc, Ilteris Oguz Topal, Aslihan Kul","doi":"10.1111/ddg.70579","DOIUrl":"https://doi.org/10.1111/ddg.70579","url":null,"abstract":"<p><strong>Background and objectives: </strong>Psoriasis is a systemic inflammatory disease affecting skin and mental health. Biologic agents targeting IL-17A and IL-23p19 effectively treat skin symptoms, but their psychiatric and systemic anti-inflammatory effects remain unclear, especially in real-life settings. This study evaluated whether IL-17A and IL-23p19 inhibitors improve psychiatric symptoms, and whether these improvements are associated with reductions in inflammatory markers, independently of skin response.</p><p><strong>Patients and methods: </strong>In this multicenter prospective study, 235 psoriasis patients starting IL-17A and IL-23p19 inhibitors were assessed at baseline and six months. Assessments included CRP, NLR, HADS-A, HADS-D, and DLQI scores.</p><p><strong>Results: </strong>Treatment significantly improved skin, quality of life, and psychiatric scores (p < 0.001). CRP declined significantly and was independently correlated with reductions in HADS-A and HADS-D scores, even in patients without PASI90 response. IL-23p19 inhibitors produced greater reductions in CRP and NLR compared to IL-17A inhibitors, suggesting broader anti-inflammatory effects through upstream cytokine blockade.</p><p><strong>Conclusions: </strong>IL-17A and IL-23p19 inhibitors improve both dermatological and psychiatric outcomes in psoriasis, potentially by reducing systemic inflammation. CRP may serve as a biomarker of psychiatric improvement, independent of skin response. Future studies with longer follow-up and non-biologic control groups are warranted. Integrating dermatological and psychiatric care may enhance outcomes in psoriasis patients.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipoid proteinosis in twin sisters: clinical, histopathological, and dermatoscopic findings.","authors":"Hazan Aksoy, Tubanur Çetinarslan, Peyker Temiz, Sertan Hancıoğlu, Aylin Türel Ermertcan","doi":"10.1111/ddg.70586","DOIUrl":"https://doi.org/10.1111/ddg.70586","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current skin of color representation in medical school dermatology education in Germany, Austria and Switzerland (DACH region).","authors":"Nina Matthes, Julian Kött, Ines Heinen, Nina Booken, Stefan W Schneider, Finn Abeck","doi":"10.1111/ddg.70529","DOIUrl":"https://doi.org/10.1111/ddg.70529","url":null,"abstract":"<p><strong>Background and objectives: </strong>Dermatologic diagnosis relies heavily on visual recognition, yet educational resources predominantly depict lighter skin types. While underrepresentation of Skin of Color (SoC) in medical education has been demonstrated in North America, data from German-speaking countries remain lacking. This study assesses the SoC representation in dermatology curricula in the DACH region (Germany, Austria, Switzerland).</p><p><strong>Methods: </strong>We conducted a questionnaire-based study targeting dermatology departments at all medical schools in the DACH region (n = 57).</p><p><strong>Results: </strong>The response rate was 65%. 89% (33/37) rated SoC curriculum integration as important or very important. 65% (24/37) already implemented SoC education in mandatory teaching. Among these, 83% (20/24) introduced SoC content within the previous 4 years. Main barriers to integration are lack of teaching materials (62%, 23/37), insufficient expertise (24%, 9/37) and limited curriculum time (22%, 8/37). 14% (5/37) reported including questions on SoC dermatology in final examinations.</p><p><strong>Conclusions: </strong>SoC is recognized as an important component of dermatology education in the DACH region. However, implementation remains inconsistent, as over a third of faculties do not offer mandatory SoC education. Access to high-quality teaching materials can be considered a key factor in strengthening SoC education. Further efforts are needed to promote diversity-sensitive education.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foot drop in generalized herpes zoster: L5‑predominant polyradiculitis as a rare complication - a case report.","authors":"Anna Malfertheiner, Alexander Mensch, Burkhard Kreft","doi":"10.1111/ddg.70533x","DOIUrl":"https://doi.org/10.1111/ddg.70533x","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ambulante Versorgung des Ulcus cruris venosum in Deutschland: Eine retrospektive Analyse von Abrechnungsdaten","authors":"Lisa Weller,&nbsp;Regina Poß-Doering,&nbsp;Thomas Grobe,&nbsp;Thomas Fleischhauer,&nbsp;Gunter Laux,&nbsp;Jona Frasch,&nbsp;Attila Altiner,&nbsp;Kerstin Protz,&nbsp;Joachim Szecsenyi,&nbsp;Jonas D. Senft","doi":"10.1111/ddg.70021x","DOIUrl":"https://doi.org/10.1111/ddg.70021x","url":null,"abstract":"&lt;p&gt;Die Behandlung chronischer Wunden stellt sowohl medizinisch als auch ökonomisch eine große Herausforderung dar. Bis zu 80 % der chronischen Ulzerationen der unteren Extremität sind auf eine chronisch-venöse Insuffizienz zurückzuführen.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; Die Prävalenz venöser Ulzera in Deutschland wird auf 0,7 %–1,4 % geschätzt und nimmt in Altersgruppen über 65 Jahren deutlich zu.&lt;span&gt;&lt;sup&gt;2, 3&lt;/sup&gt;&lt;/span&gt; Aufgrund des demografischen Wandels ist künftig mit einer Verschärfung des Versorgungssituation zu rechnen. Neben den physischen, psychischen und sozialen Krankheitsfolgen für die Betroffenen ist das Ulcus cruris venosum (UCV) mit hohen gesundheitsökonomischen Kosten und Arbeitsausfällen verbunden.&lt;span&gt;&lt;sup&gt;2, 3&lt;/sup&gt;&lt;/span&gt; Laut Versorgungsanalysen entfallen 1 %–2 % des gesamten Gesundheitsbudgets auf die Behandlungskosten.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;In Deutschland empfiehlt die kürzlich überarbeitete konsensbasierte Leitlinie zur Diagnostik und Therapie venöser Beinulzera eine frühzeitige und konsequente Kompressionstherapie für Patienten mit UCV, sofern keine Kontraindikationen vorliegen.&lt;span&gt;&lt;sup&gt;1, 5&lt;/sup&gt;&lt;/span&gt; Sie ist ein zentraler Bestandteil der konservativen Behandlung, deren Wirksamkeit auf die Wundheilung bei fachgerechter Anwendung mit einem Anlagedruck von 40–60 mmHg durch Evidenzklasse IA belegt ist.&lt;span&gt;&lt;sup&gt;6&lt;/sup&gt;&lt;/span&gt; Ihre konsequente und sachgerechte Anwendung ist mit einer geringeren Rezidivrate, einer Schmerzreduktion und einer Verbesserung der gesundheitsbezogenen Lebensqualität assoziiert.&lt;span&gt;&lt;sup&gt;6, 7&lt;/sup&gt;&lt;/span&gt; Dennoch wird die Kompressionstherapie laut Versorgungsanalysen nur in etwa 31 %–61 % der Fälle eingesetzt, wobei auch Defizite in der praktischen Umsetzung bestehen.&lt;span&gt;&lt;sup&gt;8, 9&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Das GBA-Innovationsfondsförderprojekt Ulcus Cruris Care (Nr. 01VSF19043) zielt darauf ab, auf Grundlage aktueller Leitlinien&lt;span&gt;&lt;sup&gt;1, 10, 11&lt;/sup&gt;&lt;/span&gt; und wissenschaftlicher Erkenntnisse ein evidenzbasiertes, patientenorientiertes Versorgungskonzept zur Behandlung des UCV in der hausärztlichen Praxis zu entwickeln und umzusetzen. Im Rahmen des Projekts wurden Routinedaten der gesetzlichen Krankenkasse AOK Baden-Württemberg ausgewertet, um die aktuelle ambulante Versorgungssituation zu untersuchen. Ziel der vorliegenden Analyse war insbesondere die Erfassung des Einsatzes der Kompressionstherapie als zentrales Behandlungselement, ärztlicher Konsultationen, relevanter operativer Eingriffe sowie der insgesamt entstandenen Kosten. Die Ergebnisse dieser Studie können zur Umsetzung geeigneter Interventionen beitragen und damit die ambulante Versorgung von Patienten mit UCV verbessern.&lt;/p&gt;&lt;p&gt;Open access Veröffentlichung ermöglicht und organisiert durch Projekt DEAL.&lt;/p&gt;&lt;p&gt;Das Projekt &lt;i&gt;Ulcus Cruris Care&lt;/i&gt; wird durch den Innovationsausschuss des Gemeinsamen Bundesausschusses (G-BA) gefördert (01VSF19043).&lt;/p&gt;&lt;p&gt;K.P. erhielt Honorare für Beratungen und/oder Vorträge von Bauerfeind, Essity/","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":"24 10","pages":"1426-1434"},"PeriodicalIF":5.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ddg.70021x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant cellulitis-like Sweet's syndrome induced by gilteritinib","authors":"Juan de Luque-Fernández,&nbsp;Irene Rivera-Ruiz,&nbsp;Irene Suárez-Vergne,&nbsp;Inmaculada Sánchez-Ramírez,&nbsp;Manuel Galán-Gutiérrez,&nbsp;Antonio José Vélez García-Nieto","doi":"10.1111/ddg.70179","DOIUrl":"10.1111/ddg.70179","url":null,"abstract":"&lt;p&gt;Dear Editors,&lt;/p&gt;&lt;p&gt;Neutrophilic dermatoses (ND) are a heterogeneous group of inflammatory skin disorders characterized by dense neutrophilic infiltration in the absence of infection. Among them, Sweet's syndrome (SS) is the prototypical presentation, typically manifesting as painful, erythematous plaques accompanied by fever and systemic inflammation.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;We present the case of a 67-year-old woman with relapsed NPM1/FLT3-ITD–mutated acute myeloid leukemia (AML), who was undergoing cytoreduction with hydroxyurea and induction therapy with azacitidine, venetoclax and gilteritinib. After one month of consolidation therapy with gilteritinib, she developed high fever and a tender, indurated erythematous-violaceous plaque affecting the right periorbital and malar regions (Figure 1a). The lesion was warm, painful and infiltrated, but ocular motility remained intact. Preseptal cellulitis, invasive fungal infection and leukaemia cutis were suspected. Given the patient's relapsed AML, profound cytopenia and periorbital involvement, broad-spectrum antibacterial and antifungal therapy (meropenem, vancomycin and amphotericin B) was initiated according to institutional sepsis protocols, but without improvement. In the following days, new tender plaques appeared at sites of subcutaneous low-molecular-weight heparin injections (Figure 1b,c), suggestive of pathergy.&lt;/p&gt;&lt;p&gt;Laboratory findings included leucopenia (2,560/µL), thrombocytopenia (33,000/µL), elevated C-reactive protein (314 mg/L) and low procalcitonin (0.29 ng/mL). Imaging ruled out orbital involvement. Skin biopsy revealed dense neutrophilic infiltration of the dermis and hypodermis without microorganisms (Figure 1e,f). Special stains and microbiological workup were negative. A diagnosis of giant cellulitis-like Sweet's syndrome (GCSS) was established. Gilteritinib was discontinued, and intravenous methylprednisolone (125 mg/day) was administered for five days, followed by a tapering course of oral prednisone and adjunctive topical fluticasone. Lesions resolved rapidly (Figure 1d). Colchicine 0.5 mg/day was initiated after completion of corticosteroids as maintenance therapy, and was maintained for six months until transplantation, with good tolerance. The patient underwent hematopoietic stem cell transplantation, with no recurrence at six months.&lt;/p&gt;&lt;p&gt;GCSS is a rare variant of ND characterized by extensive, erythematous, painful plaques that mimic bacterial infection.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; Systemic symptoms such as fever and elevated inflammatory markers are frequent. GCSS often leads to antibiotic overuse and delay in appropriate management.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; In our case, early biopsy was critical to avoid unnecessary prolonged antimicrobial therapy.&lt;/p&gt;&lt;p&gt;FLT3 inhibitors like gilteritinib are increasingly used in relapsed AML.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; Rash is a common adverse event,&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; but SS and other neutrophilic dermatoses are rare ","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":"24 10","pages":"e1472-e1474"},"PeriodicalIF":5.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ddg.70179","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146197547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV42 – a human papillomavirus classified as a low-risk type with oncogenic potential","authors":"Sven Niklas Burmann,&nbsp;Ulrike Wieland,&nbsp;Steffi Silling,&nbsp;Frank Oellig,&nbsp;David Chromy,&nbsp;Julia Hyun,&nbsp;Thilo Gambichler,&nbsp;Alexander Kreuter","doi":"10.1111/ddg.15981","DOIUrl":"10.1111/ddg.15981","url":null,"abstract":"<p>Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low-risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts. However, in very rare cases, HPV42 has also been identified in invasive genital tumors, particularly cervical carcinomas. In the case series presented here, HPV42 was detected in anogenital warts, a digital squamous cell carcinoma in situ, and a lymphogenously metastasized digital papillary adenocarcinoma (DPA). In the latter tumor entity, HPV42 was recently identified as the potential causative agent. Depending on the infected cell population, HPV42 can give rise to both benign lesions (anogenital warts and the rare cervicovaginal “seborrheic keratosis-like” lesion) and malignant lesions (anogenital and digital carcinomas, as well as the highly aggressive DPA). HPV42 can therefore be considered as potentially carcinogenic. With the currently available nonavalent HPV vaccine over 90% of HPV-related tumors and anogenital warts can be prevented, but not HPV42-induced lesions. These tumors will therefore not be suppressed by the current vaccination programs, even not in countries with high vaccination rates.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":"24 10","pages":"1412-1416"},"PeriodicalIF":5.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ddg.15981","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digitale Gesundheitsanwendungen, Telemedizin und Large Language Models in der Dermatologie: Ergebnisse einer deutschlandweiten Befragung","authors":"Lukas Henk,&nbsp;Leah Schirren,&nbsp;Felix Mühlensiepen,&nbsp;Claudia Traidl-Hoffmann,&nbsp;Marina Otten,&nbsp;Victor Olsavszky,&nbsp;Alexander Zink,&nbsp;Michael Hertl,&nbsp;Sebastian Kuhn,&nbsp;Johannes Knitza","doi":"10.1111/ddg.70019","DOIUrl":"https://doi.org/10.1111/ddg.70019","url":null,"abstract":"&lt;p&gt;Digitale Technologien prägen zunehmend die medizinische Versorgung und bieten insbesondere in der Dermatologie vielfältige Möglichkeiten zur Optimierung von Diagnostik und Therapie.&lt;span&gt;&lt;sup&gt;1, 2&lt;/sup&gt;&lt;/span&gt; Mit der Veröffentlichung der ersten S2k-Leitlinie zur Teledermatologie im Jahr 2020 war die Dermatologie das erste medizinische Fachgebiet in Deutschland, das sich im Rahmen einer evidenzbasierten Leitlinie systematisch mit telemedizinischen Versorgungsmodellen auseinandersetzte.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; Ergänzend formulierten die Deutsche Dermatologische Gesellschaft (DDG) und der Berufsverband der Deutschen Dermatologen (BVDD) im Jahr 2023 in einem gemeinsamen Positionspapier Perspektiven zur Weiterentwicklung digitaler Versorgungsstrukturen in der Dermatologie, wobei insbesondere die Integration von Gesundheits-Apps und Künstlicher Intelligenz sowie die Notwendigkeit spezifischer ärztlicher Qualifizierungsangebote hervorgehoben wurden.&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Eine Querschnittsbefragung aus den Jahren 2019 und 2021 dokumentierte eine Zunahme teledermatologischer Videosprechstunden während der COVID-19-Pandemie.&lt;span&gt;&lt;sup&gt;5&lt;/sup&gt;&lt;/span&gt; Aktuell sind 69 Digitale Gesundheitsanwendungen (DiGA) gelistet (Stand: Juli 2025), von denen bislang keine explizit für dermatologische Indikationen zugelassen ist. Einige Anwendungen adressieren jedoch relevante Komorbiditäten wie Depression, Raucherentwöhnung, arterielle Hypertonie oder Adipositas.&lt;span&gt;&lt;sup&gt;6, 7&lt;/sup&gt;&lt;/span&gt; DiGA werden von allen gesetzlichen Krankenkassen und von vielen privaten Krankenversicherungen erstattet. Die umfassende Prüfung von Sicherheit und Nutzen durch das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM) bietet sowohl Patienten als auch Ärzten einen entscheidenden Vorteil gegenüber den sonst häufig wechselnden und intransparenten App-Angeboten. Parallel dazu gewinnen Large Language Models (LLMs) wie ChatGPT zunehmend an Bedeutung. Potenzielle Einsatzbereiche reichen von der Unterstützung bei der Anamneseerhebung, die Generierung von Arztbriefen, die Formulierung von Patienteninformationen bis hin zur strukturierten Auswertung von Leitlinien.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; In welchem Umfang die Videosprechstunde, DiGA und LLMs von Dermatologen genutzt werden, ist bislang unklar.&lt;/p&gt;&lt;p&gt;Ziel dieser Studie war es daher, systematisch die Nutzung, Akzeptanz und wahrgenommenen Barrieren digitaler Technologien in der Dermatologie zu erfassen. Der Schwerpunkt lag insbesondere auf insbesondere DiGA und LLMs. Darüber hinaus wurde der Fortbildungsbedarf dermatologisch tätiger Ärzt*innen im Umgang mit digitalen Technologien erhoben.&lt;/p&gt;&lt;p&gt;Die Datenerhebung erfolgte digital mittels eines anonymen Online-Fragebogens (Google Forms). Die Ergebnisse wurden unter Berücksichtigung der CHERRIES-Empfehlungen (Checklist for Reporting Results of Internet E-Surveys) strukturiert berichtet.&lt;span&gt;&lt;sup&gt;8&lt;/sup&gt;&lt;/span&gt; Dermatologen wurden durch Studienpersonal im Rahmen von dermatologisc","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":"24 10","pages":"1435-1440"},"PeriodicalIF":5.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ddg.70019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}