Journal Der Deutschen Dermatologischen Gesellschaft最新文献

{"title":"Cutaneous reactions to vaccination.","authors":"Jacqueline Kussini, Stefan Mühlenbein, Dario Didona, Wolfgang Pfützner","doi":"10.1111/ddg.15477","DOIUrl":"https://doi.org/10.1111/ddg.15477","url":null,"abstract":"<p><p>Vaccination is a fundamental principle of preventive health care. Administration of the vaccine, which contains the antigen(s) of a pathogen, activates the immune system and provides protection against infection. The immunogenicity and allergenicity of a vaccine may lead to various adverse reactions, depending on the responsiveness and susceptibility of the vaccinated individual. Cutaneous adverse events are among the most common and can manifest as various local or generalized vaccination reactions. Understanding their pathogenesis and clinical manifestations is essential for therapy, for further diagnostic clarification if necessary, and for managing any booster vaccination that may be required. Appropriate dermatological expertise therefore plays a crucial role in managing patients with a history of vaccination reactions.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of female hirsutism and PCOS in the United States: A cross-sectional study.","authors":"Matthew Chen, William Nguyen, Zaim Haq, William Guo, James Briley","doi":"10.1111/ddg.15630","DOIUrl":"https://doi.org/10.1111/ddg.15630","url":null,"abstract":"<p><strong>Background: </strong>Current research on hirsutism reveals disparities and knowledge deficiencies, particularly in underrepresented cohorts. Our objective is to scrutinize demographic variances in hirsutism rates.</p><p><strong>Patients and methods: </strong>Using the All of Us database, we conducted a cross-sectional analysis encompassing 172,401 women. We calculated prevalence rates and odds ratios for hirsutism among all women and those diagnosed with polycystic ovary syndrome (PCOS), examining various epidemiological factors.</p><p><strong>Results: </strong>Among the sampled women, hirsutism prevalence was 1.37%; in PCOS-afflicted females, it was 19.12%. Asian and Hispanic women exhibited diminished hirsutism likelihoods, whereas African-American counterparts showed elevated likelihood. Additionally, females aged 60-74 and 75+ demonstrated reduced hirsutism risks. Higher education and income above $ 50,000 correlated with heightened hirsutism likelihoods. PCOS females had substantially elevated hirsutism probabilities compared to the general female cohort. Within PCOS cohorts, African-American females had heightened hirsutism rates, while Hispanic females showed lower rates.</p><p><strong>Conclusions: </strong>In conclusion, hirsutism prevalence is generally low among United States females but markedly higher in PCOS cases. Notably, certain racial, ethnic, and socioeconomic groups, both in the general populace and among PCOS patients, exhibit significantly disparate hirsutism rates.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Miliarial-type reactive B-cell rich proliferation in sun-exposed areas: a diagnostic and therapeutic challenge.","authors":"Cristina Barrabés-Torrella, Marian Sola-Casas, Noelia Pérez-Muñoz, María Teresa Fernández-Figueras, Víctor García-Rodríguez, Montse Salleras-Redonnet","doi":"10.1111/ddg.15583","DOIUrl":"https://doi.org/10.1111/ddg.15583","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"German evidence- and consensus-based guideline on the management of penile urethritis.","authors":"Ricardo Niklas Werner, Isabell Vader, Susan Abunijela, Markus Bickel, Anika Biel, Christoph Boesecke, Lisa Branke, Viviane Bremer, Norbert Hermann Brockmeyer, Susanne Buder, Stefan Esser, Ruben Heuer, Frank-Michael Köhn, Andrea Mais, Alexander Nast, Antonia Pennitz, Anja Potthoff, Heinrich Rasokat, Michael Sabranski, Sven Schellberg, Axel Jeremias Schmidt, Sebastian Schmidt, Laila Schneidewind, Sören Schubert, Caroline Schulte, Christoph Spinner, Petra Spornraft-Ragaller, Cord Sunderkötter, Udo Vester, Christoph Zeyen, Klaus Jansen","doi":"10.1111/ddg.15617","DOIUrl":"https://doi.org/10.1111/ddg.15617","url":null,"abstract":"<p><p>Urethritis is a common condition predominantly caused by sexually transmitted pathogens such as Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium. It is not possible to differentiate with certainty between pathogens on the basis of clinical characteristics alone. However, empirical antibiotic therapy is often initiated in clinical practice. The aim of this clinical practice guideline is to promote an evidence-based syndrome-orientated approach to the management of male adolescents and adults with symptoms of urethritis. Besides recommendations for the diagnosis, classification and choice of treatment, this guideline provides recommendations for the indication to empirically treat patients with penile urethritis. A novel feature compared to existing, pathogen-specific guidelines is the inclusion of a flowchart for the syndrome-orientated practical management. For suspected gonococcal urethritis requiring empirical treatment, ceftriaxone is recommended. Due to the risk of Chlamydia trachomatis co-infection, doxycycline should also be prescribed, unless follow-up for the treatment of possible co-infections is assured. For suspected non-gonococcal urethritis, doxycycline is the recommended empirical treatment. In the empiric treatment of both gonococcal and non-gonococcal penile urethritis, azithromycin is reserved for cases where doxycycline is contraindicated. This guideline also includes detailed recommendations on differential diagnosis, pathogen-specific treatments and specific situations, as well as patient counselling and follow-up.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Kaposi sarcoma a novel comorbidity of cutaneous lymphoma? A systematic review of the literature.","authors":"Rose K C Moritz, Julia Huynh, Gabriela Poch, Robert Sabat, Max Schlaak, Gabor Dobos","doi":"10.1111/ddg.15625","DOIUrl":"https://doi.org/10.1111/ddg.15625","url":null,"abstract":"<p><strong>Background and objectives: </strong>Patients with cutaneous lymphomas (CL) are at an increased risk of developing secondary malignancies. This study aimed to assess the frequency of association between CL and Kaposi sarcoma (KS) and to identify factors that may promote the co-occurrence of these two diseases.</p><p><strong>Patients and methods: </strong>On January 25, 2024, we conducted a systematic search of four electronic medical databases to identify all published cases of KS associated with CL. The clinical course and outcomes of these patients were summarized. For critical appraisal, we applied the JBI Checklist for Case Reports. The study was registered in the PROSPERO database (CRD42022313204).</p><p><strong>Results: </strong>A total of 40 articles reporting on 45 patients were assessed for eligibility. We included 27 cases in the final analysis (26 cutaneous T-cell lymphomas, 1 cutaneous B-cell lymphoma). In 71% of cases, the diagnosis of CL preceded KS. Nearly half (48%) of the patients had erythrodermic mycosis fungoides or Sézary syndrome. KS lesions were predominantly limited to the skin, with complete remission achieved in 53% of cases.</p><p><strong>Conclusions: </strong>The association between KS and CL is rare, limiting our study due to the small sample size and potential reporting bias. Skin-targeted therapies, a restricted T-cell repertoire, and impaired T-cell responses in erythrodermic CTCL patients may contribute to the development of KS.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined flap for the reconstruction of Upper-third auricular complex defects involving the helix root.","authors":"Rafael Salido-Vallejo, Inés Oteiza-Rius, Ana Morelló-Vicente, Javier Antoñanzas, Agustín España","doi":"10.1111/ddg.15631","DOIUrl":"https://doi.org/10.1111/ddg.15631","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ulceronecrotic facial masses with nasal destruction in an Epstein-Barr virus negative East Asian adult male.","authors":"Jie Wang, Grace Xiong, Dilidaer Yasen, Chaocheng Liu","doi":"10.1111/ddg.15646","DOIUrl":"https://doi.org/10.1111/ddg.15646","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of a ChatGPT-4-based chatbot in teledermatology: A retrospective exploratory study.","authors":"Jonathan Shapiro, Emily Avitan-Hersh, Binyamin Greenfield, Ziad Khamaysi, Roni P Dodiuk-Gad, Yuliya Valdman-Grinshpoun, Tamar Freud, Anna Lyakhovitsky","doi":"10.1111/ddg.15609","DOIUrl":"https://doi.org/10.1111/ddg.15609","url":null,"abstract":"<p><strong>Background and objectives: </strong>Integration of artificial intelligence in healthcare, particularly ChatGPT, is transforming medical diagnostics and may benefit teledermatology. This exploratory study compared image description and differential diagnosis generation by a ChatGPT-4 based chatbot with human teledermatologists.</p><p><strong>Patients and methods: </strong>This retrospective study compared 154 teledermatology consultations (December 2023-February 2024) with ChatGPT-4's performance in image descriptions and diagnoses. Diagnostic concordance was classified as \"Top1\" (exact match with the teledermatologist's diagnoses), \"Top3\" (correct diagnosis within one the top three diagnoses), and \"Partial\" (similar but not identical diagnoses). Image descriptions were rated and compared for quality parameters (location, color, size, morphology, and surrounding area), and accuracy (Yes, No, and Partial).</p><p><strong>Results: </strong>Out of 154 cases, ChatGPT-4 achieved a Top1 diagnostic concordance in 108 (70.8%), Top3 concordance in 137 (87.7%), partial concordance in four (2.6%), and was discordant in 15 (9.7%) cases. The quality of ChatGPT-4's image descriptions significantly surpassed teledermatologists in all five parameters. ChatGPT-4's descriptions were accurate in 130 (84.4%), partially accurate in 22 (14.3%), and inaccurate in two (1.3%) cases.</p><p><strong>Conclusions: </strong>The preliminary findings of this study indicate that ChatGPT-4 demonstrates potential in generating accurate image descriptions and differential diagnoses. These results highlight the promise of integrating artificial intelligence into asynchronous teledermatology workflows.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papulonodular mucinosis: a systematic review on clinicopathologic characteristics, course and treatment options.","authors":"Si-Yu Luo, Qin-Xiao Wang, Kai-Yi Zhou, Li-Jia Deng, Sheng Fang","doi":"10.1111/ddg.15607","DOIUrl":"https://doi.org/10.1111/ddg.15607","url":null,"abstract":"<p><p>Papulonodular mucinosis (PNM) is a rare cutaneous mucinosis recognized as a rare variant of lupus erythematosus. There are no large-scale cohort studies characterizing its clinicopathological features or evaluating the effectiveness of various treatment options. This study aimed to review the literature on PNMs to identify its clinical and histological features and treatment outcomes. The search includes studies from the PubMed, Embase, and Cochrane Library databases up to the March 1, 2024. A total of 37 studies, encompassing 44 patients, were included in the review. Of these, 20 were males and 24 females, with a mean age at diagnosis of 34.9 ± 1.92 years. PNM lesions are characterized by generalized papules, plaques, and nodules, and histopathologically, they show abundant mucin deposition throughout the dermis. The temporal relationship between PNM and SLE is variable. There is no evidence that SLE patients with PNM are more prone to organ involvement or increased disease activity. A combination of medical history, clinical features, and histopathological findings is essential for diagnosis; however, misdiagnosis is possible until lupus erythematosus (LE) becomes evident. Hydroxychloroquine and systemic glucocorticoids are the current mainstays of treatment for PNM, with most patients achieving partial or complete remission.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of cutaneous larva migrans.","authors":"Luisa Bopp, Nicolai Deresz, Mario Fabri, Esther von Stebut","doi":"10.1111/ddg.15611","DOIUrl":"https://doi.org/10.1111/ddg.15611","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}