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Journal Der Deutschen Dermatologischen Gesellschaft最新文献

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Topical ivermectin 10 mg/g cream alone or in combination with oral doxycycline for patients with perioral dermatitis (POD): A retrospective case series.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-22 DOI: 10.1111/ddg.15691
Martin Schaller, Daniela Lenders, Gabi Handgretinger, Andrea Gawaz
{"title":"Topical ivermectin 10 mg/g cream alone or in combination with oral doxycycline for patients with perioral dermatitis (POD): A retrospective case series.","authors":"Martin Schaller, Daniela Lenders, Gabi Handgretinger, Andrea Gawaz","doi":"10.1111/ddg.15691","DOIUrl":"https://doi.org/10.1111/ddg.15691","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rosacea in childhood and adolescence: A review.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-22 DOI: 10.1111/ddg.15693
Sören Korsing, Karola Stieler, Uwe Pleyer, Ulrike Blume-Peytavi, Annika Vogt
{"title":"Rosacea in childhood and adolescence: A review.","authors":"Sören Korsing, Karola Stieler, Uwe Pleyer, Ulrike Blume-Peytavi, Annika Vogt","doi":"10.1111/ddg.15693","DOIUrl":"https://doi.org/10.1111/ddg.15693","url":null,"abstract":"<p><p>Despite presenting with similar symptoms, triggers, and progression patterns as adults, rosacea in children and adolescents is frequently overlooked as a primary differential diagnosis. However, initial manifestations of classic clinical types can be observed from infancy onwards. The frequent association of childhood rosacea with ophthalmologic manifestations is of particular importance in addition to the knowledge of special subtypes such as idiopathic aseptic facial granuloma. Therapeutic options of pediatric rosacea partly overlap with those of common differential diagnoses such as acne vulgaris or perioral dermatitis. However, both the disease itself and its manifestation in this age group entail challenges in the selection of active ingredients and the development of therapeutic concepts. In addition, advice on triggering and aggravation factors is required in order to provide optimal long-term support for those affected.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated limb perfusion as a limb-saving therapy for locally advanced squamous cell carcinoma.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-21 DOI: 10.1111/ddg.15677
Maria Cristina Fialho, Ana Ferreirinha, Joana Bártolo, Victor Farricha
{"title":"Isolated limb perfusion as a limb-saving therapy for locally advanced squamous cell carcinoma.","authors":"Maria Cristina Fialho, Ana Ferreirinha, Joana Bártolo, Victor Farricha","doi":"10.1111/ddg.15677","DOIUrl":"https://doi.org/10.1111/ddg.15677","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal erythroderma in a patient with cartilage-hair hypoplasia: Identification of a novel RMRP mutation.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-20 DOI: 10.1111/ddg.15687
María López-Pardo Rico, Noelia Moreiras Arias, Cecilia Buján Bonino, Benigno Monteagudo Sánchez, Patricia Pérez Feal, Graciela Gómez Silva, José Manuel Suárez Peñaranda, Igor Vázquez Osorio
{"title":"Neonatal erythroderma in a patient with cartilage-hair hypoplasia: Identification of a novel RMRP mutation.","authors":"María López-Pardo Rico, Noelia Moreiras Arias, Cecilia Buján Bonino, Benigno Monteagudo Sánchez, Patricia Pérez Feal, Graciela Gómez Silva, José Manuel Suárez Peñaranda, Igor Vázquez Osorio","doi":"10.1111/ddg.15687","DOIUrl":"https://doi.org/10.1111/ddg.15687","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Capnocytophaga canis erysipelas and bacteremia in an immunocompetent patient.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-19 DOI: 10.1111/ddg.15684
Gabriela Blanchard, Maël Blanchard, Manon Rosselin, Géraldine Jost, Nadia Liassine, Laurence Toutous-Trellu, David Alvarez Martinez
{"title":"Capnocytophaga canis erysipelas and bacteremia in an immunocompetent patient.","authors":"Gabriela Blanchard, Maël Blanchard, Manon Rosselin, Géraldine Jost, Nadia Liassine, Laurence Toutous-Trellu, David Alvarez Martinez","doi":"10.1111/ddg.15684","DOIUrl":"https://doi.org/10.1111/ddg.15684","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neoadjuvant treatment with immune checkpoint inhibitors in patients with melanoma: A real-life retrospective study.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-17 DOI: 10.1111/ddg.15632
Dirk Tomsitz, Petra Zimmermann, Wolfgang G Kunz, Jens Neumann, Birte J Siegmund, Bernhard G Weiss, Teresa Kauke, Wulf Sienel, Lars E French, Frederick Klauschen, Lucie Heinzerling
{"title":"Neoadjuvant treatment with immune checkpoint inhibitors in patients with melanoma: A real-life retrospective study.","authors":"Dirk Tomsitz, Petra Zimmermann, Wolfgang G Kunz, Jens Neumann, Birte J Siegmund, Bernhard G Weiss, Teresa Kauke, Wulf Sienel, Lars E French, Frederick Klauschen, Lucie Heinzerling","doi":"10.1111/ddg.15632","DOIUrl":"https://doi.org/10.1111/ddg.15632","url":null,"abstract":"<p><strong>Background: </strong>Neoadjuvant treatment with ipilimumab and nivolumab has shown efficacy in melanoma patients with nodal metastases in clinical trials. Real world data on neoadjuvant therapies is lacking.</p><p><strong>Patients and methods: </strong>This study investigates the effectiveness of neoadjuvant therapy in a real-world setting and included all melanoma patients who received combined anti-CTLA4/PD1 immunotherapy prior to resection. Pathologic and radiologic responses as well as treatment-related adverse events were assessed, and recurrence-free survival (RFS) was compared between patients with major pathologic response (mPR) and patients without mPR.</p><p><strong>Results: </strong>In total, 24 patients were analyzed, including patients with distant metastases and patients with prior adjuvant treatment. Median follow-up was 21.5 months. Upon histologic assessment, mPR was achieved in 50% (12/24) of the patients, including two patients with lung metastases and three patients who progressed after prior adjuvant anti-PD1 therapy. Radiologic response after neoadjuvant treatment correlated with mPR. No patient with mPR relapsed during follow-up (median RFS not reached) compared to six out of 12 patients without mPR (median RFS = 13 months, p = 0.005).</p><p><strong>Conclusions: </strong>Neoadjuvant treatment with ipilimumab and nivolumab is effective in real-world patients with different melanoma subtypes, different stages of disease and even advanced primary tumor.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematics, diagnosis and treatment of wound infections in chronic wounds: A position paper from WundDACH.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-17 DOI: 10.1111/ddg.15649
Joachim Dissemond, Julian-Dario Rembe, Bernd Assenheimer, Marjam Barysch-Bonderer, Veronika Gerber, Jan Kottner, Peter Kurz, Martin Motzkus, Eva-Maria Panfil, Sebastian Probst, Robert Strohal, Jürg Traber, Andreas Schwarzkopf
{"title":"Systematics, diagnosis and treatment of wound infections in chronic wounds: A position paper from WundDACH.","authors":"Joachim Dissemond, Julian-Dario Rembe, Bernd Assenheimer, Marjam Barysch-Bonderer, Veronika Gerber, Jan Kottner, Peter Kurz, Martin Motzkus, Eva-Maria Panfil, Sebastian Probst, Robert Strohal, Jürg Traber, Andreas Schwarzkopf","doi":"10.1111/ddg.15649","DOIUrl":"https://doi.org/10.1111/ddg.15649","url":null,"abstract":"<p><p>Wound infections are still an interdisciplinary and interprofessional challenge, because of numerous complications, particularly in people with chronic wounds. There are many different concepts and approaches in this field today. Therefore, WundDACH, the umbrella organization of the German-speaking wound healing societies, wrote a position paper on this important topic. An interdisciplinary and interprofessional group of experts from German-speaking countries developed definitions and procedures for nomenclature, diagnosis and treatment of wound infections in people with chronic wounds in a modified Delphi process. The importance of correctly diagnosing wound infections is emphasized so that adequate treatment can be carried out as early and specifically as possible. For a differentiated assessment, a simplified continuum of wound infection with contamination, colonization, local and systemic infection and the corresponding therapeutic consequences was described. Most bacteria in wounds can be removed by repeated wound-irrigation and debridement. Local wound infections are diagnosed based on clinical signs of infection and TILI score. Treatment is then usually exclusively local, for example with modern antiseptics such as polyhexanide. Systemic antibiotics should mostly be considered when signs of systemic infections appear. The indication for antimicrobial wound therapy should be critically reviewed after 10-14 days at the latest.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous-limited, initially strongly unilateral microscopic polyangiitis.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-17 DOI: 10.1111/ddg.15675
Roman Saternus, Thomas Vogt, Zanir Abdi
{"title":"Cutaneous-limited, initially strongly unilateral microscopic polyangiitis.","authors":"Roman Saternus, Thomas Vogt, Zanir Abdi","doi":"10.1111/ddg.15675","DOIUrl":"https://doi.org/10.1111/ddg.15675","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143648769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age is not an obstacle: Tumor excisions under local anesthesia even in very old people.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-13 DOI: 10.1111/ddg.15689
Angelika Ries, Edgar Dippel, Christoph R Löser
{"title":"Age is not an obstacle: Tumor excisions under local anesthesia even in very old people.","authors":"Angelika Ries, Edgar Dippel, Christoph R Löser","doi":"10.1111/ddg.15689","DOIUrl":"https://doi.org/10.1111/ddg.15689","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathophysiological insights into the successful treatment of EBV-positive hydroa vacciniforme lymphoproliferative disorder with hydroxychloroquine.
IF 5.5 4区 医学
Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2025-03-12 DOI: 10.1111/ddg.15683
Christina Bürgler, Lukas Meyer-Landolt, Stefanie Häfliger, Roland Blum, Antonia Reimer-Taschenbrecker, Luca Borradori, Ronald Wolf
{"title":"Pathophysiological insights into the successful treatment of EBV-positive hydroa vacciniforme lymphoproliferative disorder with hydroxychloroquine.","authors":"Christina Bürgler, Lukas Meyer-Landolt, Stefanie Häfliger, Roland Blum, Antonia Reimer-Taschenbrecker, Luca Borradori, Ronald Wolf","doi":"10.1111/ddg.15683","DOIUrl":"https://doi.org/10.1111/ddg.15683","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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