Journal Der Deutschen Dermatologischen Gesellschaft最新文献_第2页

Biologic treatments for psoriasis have different anatomical specificities in residual PASI. 银屑病的生物治疗在残余PASI中具有不同的解剖学特异性。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2025-10-11 DOI: 10.1111/ddg.15924

Martina Burlando, Irene Schiavetti, Aurora Parodi, Emanuele Cozzani, Luca Mastorino, Eleonora Bongiovanni, Ilaria Salvi, Martina Del Vecchio, Paolo Dapavo

{"title":"Biologic treatments for psoriasis have different anatomical specificities in residual PASI.","authors":"Martina Burlando, Irene Schiavetti, Aurora Parodi, Emanuele Cozzani, Luca Mastorino, Eleonora Bongiovanni, Ilaria Salvi, Martina Del Vecchio, Paolo Dapavo","doi":"10.1111/ddg.15924","DOIUrl":"10.1111/ddg.15924","url":null,"abstract":"Background and objectives: Improved understanding of the immunopathogenesis of psoriasis has led to the development of effective targeted therapies, but patients who respond to treatment without total skin clearance have residual disease. The aim of this study was to demonstrate the existence of specific residual disease (or residual PASI) anatomical localizations related to different biologic agents.Methods and patients: This retrospective, observational, multi-center study analyzed clinical data of patients affected by psoriasis who had received biologic treatments for at least 6 months. The data analysis focused on patients with residual PASI.Results: A total of 228 of 1,000 patients showed residual disease despite achieving PASI 90 at weeks 24-28 of biologic treatment. The anatomical sites most frequently involved in residual disease were the lower limbs (44.3%). We observed differences among the biologic agents in terms of frequency and localization of residual disease. The localization of residual skin lesions to lower limbs was associated with treatment switching/interruption. The drugs with the highest and lowest proportion of patients with residual disease in the lower limbs were, respectively, secukinumab and risankizumab.Conclusions: Treatment with anti-IL-17 and anti-IL-23 drugs is characterized by the persistence of residual skin lesions with differences in terms of frequency and anatomical localizations.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":"628-632"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13140115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145274538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital cataract and slowly progressing facial skin lesions in a 5-year-old boy. 先天性白内障和缓慢进展的面部皮肤病变的5岁男孩。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2026-01-13 DOI: 10.1111/ddg.15973

Julia Limmer, Cristina Has, Kilian Eyerich, Anna Caroline Pilz

引用次数: 0

Bullous Wells' syndrome successfully treated with omalizumab. omalizumab成功治疗大疱性威尔斯综合征。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2025-12-12 DOI: 10.1111/ddg.15964

Giulia Ciccarese, William Andrew Rosato, Francesco Drago, Alexandre Raphael Meduri, Francesca Ambrogio, Aurora De Marco, Gerardo Cazzato, Caterina Foti

引用次数: 0

Clindamycin and daptomycin failure in PVL-positive MRSA infection of the skin and soft tissue. 克林霉素和达托霉素在pvl阳性MRSA皮肤和软组织感染中的失效。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2026-01-07 DOI: 10.1111/ddg.15988

Michael Zolotas, Kamran Ghoreschi, Ulrike Blume-Peytavi, Rasmus Leistner, Daniel Humme

引用次数: 0

Kongresskalender 2026. Kongresskalender 2026年.

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 DOI: 10.1111/ddg.70399

引用次数: 0

High-risk basal cell carcinoma on the scrotum. 阴囊高危基底细胞癌。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2026-01-12 DOI: 10.1111/ddg.15983

Stefanie Lischker, Edgar Dippel, Christoph R Löser

引用次数: 0

S2k guideline occupational skin products: skin protection creams, skin cleansing and skin care products. S2k指南职业护肤产品：护肤霜、洁肤和护肤产品。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2026-03-16 DOI: 10.1111/ddg.70005x

Michal Gina, Manigé Fartasch, Andrea Bauer, Hans Drexler, Peter Elsner, Johannes Geier, Swen Malte John, Sybille Schliemann, Christiane Altenburg, Richard Brans, Dominique Jasmin Lunter, Alexander Nast, Birgit Pieper, Axel Schlieter, Petra Staubach, Anja Thielitz, Christoph Zeyen

{"title":"S2k guideline occupational skin products: skin protection creams, skin cleansing and skin care products.","authors":"Michal Gina, Manigé Fartasch, Andrea Bauer, Hans Drexler, Peter Elsner, Johannes Geier, Swen Malte John, Sybille Schliemann, Christiane Altenburg, Richard Brans, Dominique Jasmin Lunter, Alexander Nast, Birgit Pieper, Axel Schlieter, Petra Staubach, Anja Thielitz, Christoph Zeyen","doi":"10.1111/ddg.70005x","DOIUrl":"10.1111/ddg.70005x","url":null,"abstract":"The AWMF S1 guideline 013/056 \"Occupational Skin Products: Protective Creams, Skin Cleansers and Skin Care Products\" from 2014 has been revised and upgraded to S2K level. The aim was to develop a decision aid for the optimal use of occupational skin products for the prevention of hand eczema in the workplace. The multidisciplinary expert commission included representatives from dermatology, occupational medicine and dermopharmaceutical societies, as well as from German Social Accident Insurance. The update was conducted through a non-systematic review of current (inter)national scientific literature, focusing on randomized controlled clinical trials. The revised guideline integrates: (1) epidemiological studies demonstrating the effectiveness of skin protection and care, (2) results from the Cochrane Review on the primary prevention of occupational hand eczema, (3) skin physiological multicenter studies on the application and benefits of skin protection creams and the tolerability of skin cleansing products, (4) specific investigations on wet work, and (5) current positions on aluminum chlorohydrate and contact allergens based on opinions of the Scientific Committee on Consumer Safety (SCCS) and data from the Information Network of Departments of Dermatology (IVDK). The recommendations and key statements were agreed upon in a structured consensus conference using a nominal group process under professional moderation. The S2K guideline aims to improve the prevention of occupational hand eczema and promote the health of employees.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":"700-711"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13140142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147468020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Baricitinib for traditional Chinese medicine-induced drug reaction with eosinophilia and systemic symptoms: a case report. 巴西替尼治疗嗜酸性粒细胞增多及全身症状的中药药物反应1例。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2026-02-01 DOI: 10.1111/ddg.15979

Bin Peng, Mengyao Yi, Xueshan Du, Yanting Liu, Kun Guo, Cheng Feng, Songmei Geng

引用次数: 0

Deciphering atopic dermatitis heterogeneity: a short review on the translational revolution from endotypes to immunotypes. 解读特应性皮炎的异质性：从内源性到免疫型的转化革命的简短回顾。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2025-12-13 DOI: 10.1111/ddg.15991

Alvaro Prados-Carmona, Husein Husein-ElAhmed, Francisco J Navarro-Triviño, Ricardo Ruiz-Villaverde

{"title":"Deciphering atopic dermatitis heterogeneity: a short review on the translational revolution from endotypes to immunotypes.","authors":"Alvaro Prados-Carmona, Husein Husein-ElAhmed, Francisco J Navarro-Triviño, Ricardo Ruiz-Villaverde","doi":"10.1111/ddg.15991","DOIUrl":"10.1111/ddg.15991","url":null,"abstract":"Atopic dermatitis is the most prevalent chronic inflammatory skin disease, classically defined by its eczematous lesions and relapsing course. However, growing evidence over the past decade has revealed that this disease is in fact far more heterogeneous than previously thought - both in its clinical manifestations and in the underlying molecular and immunological mechanisms. This short review explores the evolving conceptual framework used to analyze atopic dermatitis, encompassing clinical presentations (phenotypes), immune polarization profiles (immunotypes), and the background disease-related and context-related factors that shape them. The aim of this review is to highlight how such heterogeneity influences disease severity, progression, and therapeutic response, particularly in the context of increasingly personalized treatment strategies. By synthesizing accumulated scientific and clinical insights, this short review provides clinicians with a practical guide to navigating the complex spectrum of AD and its underlying therapeutic targets. Recognizing and interpreting this multidimensional variability is essential for understanding disease course and optimizing treatment selection.","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":"602-606"},"PeriodicalIF":3.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145742747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heuristics, biases, and cognitive pitfalls of emergency teledermatology: Navigating the fine line between making and avoiding diagnostic errors. 急诊远程皮肤科的启发式、偏见和认知陷阱：在制造和避免诊断错误之间的微妙界限中导航。

IF 3.8 4区医学

Journal Der Deutschen Dermatologischen Gesellschaft Pub Date : 2026-05-01 Epub Date: 2025-12-09 DOI: 10.1111/ddg.16003

Charbel Skayem, Tu-Anh Duong

引用次数: 0