Journal Der Deutschen Dermatologischen Gesellschaft最新文献

{"title":"Yellowish auricular papules in a child.","authors":"Eduardo Rozas-Muñoz, Joan Mir-Bonafé, Jaime Piquero-Casals, Rodrigo Araya-Rojas, Juan Andrés Madariaga","doi":"10.1111/ddg.15713","DOIUrl":"https://doi.org/10.1111/ddg.15713","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tofacitinib treatment for acquired reactive perforating collagenosis.","authors":"Xingyu Jiang, Jianfeng Zheng, Yuling Shi","doi":"10.1111/ddg.15726","DOIUrl":"https://doi.org/10.1111/ddg.15726","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Local recurrence of non-lentigo maligna melanoma in situ and safety excision margins: A systematic review.","authors":"Clio Dessinioti, Aggeliki Befon, Alexander J Stratigos","doi":"10.1111/ddg.15699","DOIUrl":"https://doi.org/10.1111/ddg.15699","url":null,"abstract":"<p><p>The strength of evidence supporting a 2-step wide local excision (WLE) with 5 mm safety margins for melanoma in situ non-lentigo maligna (non-LM) type, compared with narrower margins, is unclear. This review aims to compare the frequency of local recurrence (LR) with different safety margins, after the complete surgical excision (R0) of non-LM MIS. We performed a systematic literature search in PubMed, Scopus, and the Cochrane Library up to March 17, 2024. The PRISMA checklist was used. Of 3,047 articles retrieved, seven retrospective studies were included, enrolling a total of 1,526 non-LM MIS cases excised with clear safety margins, after WLE (6 studies) or Mohs surgery (1 study). Most non-LM MIS were located on the trunk/extremities (68%-100%). Narrower margins were used in four studies, ranging from no WLE to 4 mm, and there was only one LR. Standard or wider margins were used in the remaining three studies reporting only two LR. The median follow-up ranged from 48 months to 6.6 years. The overall certainty and quality of evidence were very low. These findings of our systematic review highlight that current guidelines recommending the re-excision for non-LM MIS with clear initial margins lack strong evidence in support of this practice.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination of LED illumination and daylight photodynamic therapy for the treatment of actinic keratosis in solid organ transplant recipients: a prospective, randomized, comparative, intra-patient study.","authors":"Inés Oteiza-Rius, Ana Morelló-Vicente, Leyre Aguado-Gil, Elisa María Gómez-González, Deiane Marcos-Muñagorri, Ane Carrera-Gabilondo, Rafael Salido-Vallejo","doi":"10.1111/ddg.15665","DOIUrl":"https://doi.org/10.1111/ddg.15665","url":null,"abstract":"<p><strong>Background and objectives: </strong>Solid organ transplant recipients have an increased risk of developing actinic keratosis. Recent studies show greater effectiveness when combining daylight photodynamic therapy with a posterior LED illumination for their treatment in immunocompetent patients. The aim of this study was to compare the effectiveness of combining daylight photodynamic therapy and LED illumination versus daylight photodynamic therapy alone for the treatment of actinic keratosis in solid organ transplant recipients.</p><p><strong>Patients and methods: </strong>This randomized intra-patient study was conducted at University of Navarra Clinic. Solid organ transplant recipients with two 25 cm² areas on the face or scalp with at least four actinic keratosis, were included. After receiving daylight photodynamic therapy in both areas, one of them was randomized to receive complementary LED illumination. The primary endpoint was the reduction of the baseline actinic keratosis at 3 months post-treatment.</p><p><strong>Results: </strong>Thirteen patients with a total of 169 AKs were recruited. At 12 weeks post-treatment, the area treated with daylight and conventional photodynamic therapy showed a greater reduction in actinic keratoses (79.55% vs. 65.43%, p < 0.05).</p><p><strong>Conclusions: </strong>Our results suggest greater effectiveness of combining daylight photodynamic therapy with LED illumination compared to daylight photodynamic therapy alone for the treatment of actinic keratosis in solid organ transplant recipients.</p>","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple tender erythematous nodules and pseudo-vesicles in a 52-year-old female farmer.","authors":"Ming-Che Chiang, Ying-Yi Chiang","doi":"10.1111/ddg.15715","DOIUrl":"https://doi.org/10.1111/ddg.15715","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atraumatic surgical technique for post-traumatic ingrown fingernails.","authors":"Simona Sabulyte, Galina Balakirski, Christoph R Löser","doi":"10.1111/ddg.15698","DOIUrl":"https://doi.org/10.1111/ddg.15698","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mnemonic of three cutaneous C's - Essential questions of history taking in dermatology.","authors":"Alexander Salava","doi":"10.1111/ddg.15795","DOIUrl":"https://doi.org/10.1111/ddg.15795","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zinkmangelassoziierte Dermatitis bei einem frühgeborenen Säugling","authors":"Jennifer Grötsch,&nbsp;Michael Sticherling","doi":"10.1111/ddg.15637_g","DOIUrl":"https://doi.org/10.1111/ddg.15637_g","url":null,"abstract":"&lt;p&gt;Ein 6 Monate alter männlicher Säugling wurde in unserer dermatologischen Ambulanz vorgestellt. Klinisch zeigten sich scharf begrenzte, schuppige und verkrustete Erytheme an Wangen und Hals sowie orale Erosionen. Im Alter von 3,5 Monaten hatte der Säugling erstmals Hautveränderungen an den Ohrläppchen entwickelt. Zwei Monate später folgte allgemeine Schwäche aufgrund eingeschränkter Nahrungsaufnahme durch orale Schleimhauterosionen. Unter Anwendung lokaler Antiseptika und Antimykotika sowie unter Einsatz systemischer Antibiotika konnte keine ausreichende und anhaltende Verbesserung der Symptome erzielt werden.&lt;/p&gt;&lt;p&gt;Die Vorstellung in unserer Ambulanz erfolgte aufgrund einer fortschreitenden Verschlechterung des Hautbefundes sowie des Allgemeinzustandes. Nach einer vorzeitigen Amnionruptur in der 30. Schwangerschaftswoche wurde der Junge 7 Wochen vor dem errechneten Geburtstermin (33. Schwangerschaftswoche) spontan geboren, nach einer ansonsten unauffälligen Schwangerschaft. Es folgte eine prophylaktische Behandlung mit Ampicillin und Gentamicin über 7 Tage. Vorausgegangene Diarrhoen, andere Vorerkrankungen, eine Dauermedikation oder Allergien lagen nicht vor. Beide Eltern waren gesund, beim Onkel war eine atopische Dermatitis und allergische Rhinokonjunktivitis bekannt. Haustiere im Haushalt oder Auslandsreisen wurden ausgeschlossen. Die Mutter hatte sich vor der Schwangerschaft vegetarisch ernährt, jedoch zu Beginn der Schwangerschaft auf eine ausgewogene Ernährung mit Fleischverzehr umgestellt. Zum Zeitpunkt der Vorstellung wurde der Junge noch voll gestillt.&lt;/p&gt;&lt;p&gt;Klinisch zeigten sich an den Wangen und zervikal scharf begrenzte, blitzförmig konfigurierte, teils konfluierende Erytheme mit randbetonter, mittellamellärer Schuppung und weißlich-gelblicher Verkrustung (Abbildung 1a). Oberlippe und die Stirn waren nicht betroffen, während enoral kleine, punktförmige Erosionen am harten Gaumen sichtbar waren (Abbildung 1b). Bei der klinischen Untersuchung zeigten sich keine weiteren pathologischen Befunde. Die Lymphknoten präaurikulär, retroaurikulär und zervikal waren nicht vergrößert und unauffällig palpabel. Die bisherige Entwicklung des Säuglings erschien altersgerecht.&lt;/p&gt;&lt;p&gt;In den Hautabstrichen konnten weder bakterielle noch mykologische Erreger nachgewiesen werden. Die klinisch-chemische Laboruntersuchung ergab einen stark erniedrigten Serum-Zinkspiegel von 0,11 mg/l (Referenzbereich: 0,70–1,10 mg/l). Alle anderen bestimmten Laborparameter (Elektrolyte, Leber- und Nierenwerte, C-reaktives Protein und Differenzialblutbild) waren unauffällig.&lt;/p&gt;&lt;p&gt;Im Rahmen einer erweiterten Diagnostik lag der Serum-Zinkspiegel der Mutter mit 0,77 mg/l im Normbereich (Referenzbereich: 0,70–1,10 mg/l), ebenso wie der Zinkgehalt in der Muttermilch zu verschiedenen Zeitpunkten während der Stillzeit (1. Messung, Säuglingsalter 5,5 Monate: 354 µg/l, 2. Messung, Säuglingsalter 12 Monate: 288 µg/l; Referenzbereich: 170–3020 µg/l).&lt;/p&gt;&lt;p&gt;Eine Verbesserung des Haut","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":"23 4","pages":"509-512"},"PeriodicalIF":5.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ddg.15637_g","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"9. Tropen- und Reisedermatologischer Kurs der DDG und der ISDT, Bangkok/Thailand, 12.–17.September 2024","authors":"Isaak Effendy,&nbsp;Helmut Schöfer","doi":"10.1111/ddg.15733_g","DOIUrl":"https://doi.org/10.1111/ddg.15733_g","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":"23 4","pages":"548-552"},"PeriodicalIF":5.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kongresskalender 2025","authors":"","doi":"10.1111/ddg.15798","DOIUrl":"https://doi.org/10.1111/ddg.15798","url":null,"abstract":"","PeriodicalId":14758,"journal":{"name":"Journal Der Deutschen Dermatologischen Gesellschaft","volume":"23 4","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143801528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}