Japanese Journal of Oral Biology最新文献_第7页

Changes in Reflex Responses of the Masticatory Muscle during Sleep in Freely Behaving Rabbits 自由行为兔睡眠时咀嚼肌反射反应的变化

Japanese Journal of Oral Biology Pub Date : 2001-08-20 DOI: 10.2330/JORALBIOSCI1965.43.353

M. Inoue

{"title":"Changes in Reflex Responses of the Masticatory Muscle during Sleep in Freely Behaving Rabbits","authors":"M. Inoue","doi":"10.2330/JORALBIOSCI1965.43.353","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.353","url":null,"abstract":"顎顔面,四肢の骨格筋は,覚醒時に比較して睡眠時, ことに賦活睡眠(active sleep, AS)時に強い抑制を受けることが,これまで行われてきた神経生理学的研究により明らかにされてきた1-6)。これらの抑制は,脳幹内に存在する睡眠相依存性に活動する抑制性ニューロンによって引き起こされた運動神経のIPSPによるものである1,5,7)と同時に,舌下神経等においては縫線核ニューロンの活動低下に伴う脱促通効果8,9)であり,さらにAS期の急速眼球運動(rapid eye movement, REM)時には, これら運動神経の膜電位はさらに過分極することが報告されている3,10)。AS時には運動抑制だけでなく感覚情報が一次終末においてシナプス前抑制を受けるなど,生体の活動性が低下する11-13)にもかかわらず,REMや筋の攣縮,体動等の相反する現象も存在する。一方,四肢の運動神経において,AS時に特徴的な自発性活動電位が存在することがChaseらによって指摘された14)。すなわち,AS時には強い運動抑制が存在するにもかかわらず, それを打ち消して余りある興奮性の入力が存在するというものである。本研究では,自由行動下のウサギを用いて,咬筋および顎二腹筋運動神経の興奮性が睡眠時にどのような変調をみせるかについてを,閉口反射,開口反射に着目して記録し,比較検討を行った。慢性記録","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"45 1","pages":"353-359"},"PeriodicalIF":0.0,"publicationDate":"2001-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80946666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tubule Clustered Body Accompanied with Glycogen Particles in the Striated Duct Cell of Submandibular Gland of the Volcano Rabbit, Romerolagus diaz 火山兔颌下腺横纹管细胞中伴糖原颗粒的小管簇体

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.325

T. Mineda

引用次数: 0

Kinetic Consideration of Ca Transport and Associated Crystal Precipitation in an in vitro Precipitation Model Using Dialysis Membranes: Fluoride-dependent Regulation of Ca Concentration in Liquid Environment 透析膜体外沉淀模型中钙转运和相关晶体沉淀的动力学考虑:液体环境中钙浓度的氟化物依赖性调节

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.278

M. Hattori, Y. Taya, Kaori Sato, T. Aoba

{"title":"Kinetic Consideration of Ca Transport and Associated Crystal Precipitation in an in vitro Precipitation Model Using Dialysis Membranes: Fluoride-dependent Regulation of Ca Concentration in Liquid Environment","authors":"M. Hattori, Y. Taya, Kaori Sato, T. Aoba","doi":"10.2330/JORALBIOSCI1965.43.278","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.278","url":null,"abstract":"To elucidate how the fluid environment in forming enamel is modified by ion transport through the ameloblasts and associated extracellular events, we studied precipitation reactions in an experimental model utilizing a dialysis chamber. The experimental set-up comprised of upper and lower compartments, which were separated by a dialysis membrane of various cut-off sizes. Synthetic hydroxyapatite and pig enamel proteins were used as seeds and adsorbates, respectively. Seed crystals with or without proteincoating were placed in the lower compartment. Upon feeding the supersaturated solution (containing 1mM or 0.5mM Ca) in the upper compartment, Ca ion was allowed to diffuse into the lower compartment according to the existing concentration gradients. By monitoring time-sequential changes in Ca concentration in the lower solution, we found that Ca supply through the membrane was a rate-determining step, so the Ca concentration in the medium surrounding seed crystals became in proximity to the steady-state condition, under which the Ca concentration ([Ca] s) was maintained at lower levels than that of the supersaturated solution filling the upper compartment. The establishment of [Ca] s in the mineralizing milieu was speculated to be due to the kinetic difference between Ca supply and consumption for precipitation because [Ca] s levels were affected markedly by the presence of regulators (i. e., enamel proteins and fluoride) for precipitation. Notably, fluoride at 1ppm or lower levels exerted decreasing effects on [Ca] s, due to accelerating the precipitation kinetics and lowering the solubility of precipitated fluoridated crystals. The overall results obtained support the importance of the multitudinous physico-chemical processes in determin- ing the fluid composition surrounding forming enamel mineral.","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"22 1","pages":"278-291"},"PeriodicalIF":0.0,"publicationDate":"2001-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83941708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Analysis of the Central Pathway of the Trigeminal-Salivary Reflex by the Spinal Trigeminal Tractotomy 脊髓三叉神经束切开术对三叉-唾液腺反射中枢通路的分析

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.268

Yoshimasa Imaminato, K. Ishizuka, T. Murakami

{"title":"Analysis of the Central Pathway of the Trigeminal-Salivary Reflex by the Spinal Trigeminal Tractotomy","authors":"Yoshimasa Imaminato, K. Ishizuka, T. Murakami","doi":"10.2330/JORALBIOSCI1965.43.268","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.268","url":null,"abstract":"The aim of this study was to clarify the role of spinal trigeminal subnucleus interporalis (Sp 5 I) and subnucleus caudalis (Sp 5 C) on the trigeminal-salivary reflex. Extracellular recordings were made from a total of 119 superior salivatory nucleus (SSN) neurons innervating the submandibular and sublingual glands in urethane-chloralose anaesthetized cats. Responses to stimulation of the inferior alveolar (IA) nerve were investigated in trigeminal tractotomized animals at the level of the obex (Sp 5 C animals) and at the level of 2.5-3mm rostral from the obex (Sp 5 I animals) as well as in non-tractotomized (control) animals. In control, Sp 5 C and Sp 5 I animals, 50% (23/46), 46% (15/33) and 10% (4/40) of the identified SSN neurons orthodromically responded to stimulation of the IA nerve, respectively.In Sp 5 C animals, no significant reduction of the response rate was found in comparison with control animals, and there was no significant difference in the mean onset latency between control and Sp 5 C animals. However, only the responses activated by the medium-threshold afferent fibres or by high-threshold afferent fibres could be observed.In Sp 5 I animals, a marked reduction of the response rate was noted in comparison with control animals, and there was no significant difference in the mean onset latency between control and Sp 5 I animals. However, only the responses excited by the medium-threshold afferent fibres or by high-threshold afferent fibres could be observed.As the relay nucleus in the trigeminal-salivary reflex, Sp 5 I has a more important role and Sp 5 C has a lesser role.","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"137 1","pages":"268-277"},"PeriodicalIF":0.0,"publicationDate":"2001-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89765917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Morphological Studies on the Lingual Papillae and Their Connective Tissue Cores in the Swamp Wallaby, Wallabia bicolar 沼泽小袋鼠舌乳头及其结缔组织核的比较形态学研究

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.292

Takashi Abe, K. Koizumi, Kan Kobayashi

{"title":"Comparative Morphological Studies on the Lingual Papillae and Their Connective Tissue Cores in the Swamp Wallaby, Wallabia bicolar","authors":"Takashi Abe, K. Koizumi, Kan Kobayashi","doi":"10.2330/JORALBIOSCI1965.43.292","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.292","url":null,"abstract":"有袋類で, カンガルー科に属するオグロワラビーの舌乳頭の微細形態について, 動物種の食性と関連づけて比較解剖学的に検討した。舌背の後半部には草食性動物に特徴的な左右の臼歯間にわずかな舌隆起部 (臼歯間隆起部) が存在した。舌背に密集する糸状乳頭は1本の槍先状の主突起と複数の細長い副突起からなっていた。舌隆起部の糸状乳頭は副突起の数が多く, 長いものが多かった。糸状乳頭の結合織芯は板状の主突起と6-10本の小杆状突起からなり, それらの形状は舌背の部位により多少異なるが, 基本的には肉食性のイヌ, ネコのものに似た船の舳先状を呈していた。茸状乳頭は舌背の舌縁部に散在し, 舌尖下面の舌縁に特に多く認められた。これらの結合織芯は円柱状の細長いものから太めのものまであり, 円柱の頂上には1-数個の味蕾をのせる小陥凹が存在していた。有郭乳頭は舌後方に3個存在し, 中央乳頭の先端がわずかに表面に出る閉鎖型で, 中央乳頭の溝側上皮内に多数の味蕾が並んでいた。舌後方の外側縁に葉状乳頭はなく, 数本の円錐乳頭様構造物である外側器官が並んでいたが, 味蕾は欠如していた。舌根部の表面は乳頭を欠如し平坦であった。茸状乳頭の結合織芯の形状と3個の有郭乳頭や突出した外側器官の存在などはツパイと基本的に近似していた。糸状乳頭の外形や結合織芯の形態, それに円錐状の外側器官をもつといった所見から, オグロワラビーはイヌ, ネコなど肉食性の祖先の特徴を保持しながら, オーストラリア大陸でツパイに近縁の草食性の動物へと進化を遂げた動物であることが推測された。","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"103 1","pages":"292-309"},"PeriodicalIF":0.0,"publicationDate":"2001-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79432549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Bone Formation and Microvascular Changes after Placement of Sandblasted and Acid-etched (SLA) and Titanium Plasma-splayed (TPS) Implants in Dogs 喷砂和酸蚀(SLA)和钛等离子体(TPS)植入犬后骨形成和微血管的变化

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.316

M. Matsuo, Takatsuna Nakamura, Kazuto Takahashi

{"title":"Bone Formation and Microvascular Changes after Placement of Sandblasted and Acid-etched (SLA) and Titanium Plasma-splayed (TPS) Implants in Dogs","authors":"M. Matsuo, Takatsuna Nakamura, Kazuto Takahashi","doi":"10.2330/JORALBIOSCI1965.43.316","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.316","url":null,"abstract":"In this study we investigated vascular regeneration and bone formation in regard to the morphological view and image analysis.The mandibular molars of beagle dogs were extracted, and healing was allowed for 90 days. A sandblasted and acid-etched (SLA) implant was inserted on one side and as a control, a titanium plasma-splayed (TPS) implant was inserted on the contralateral side. Vascular resin injection was given at 3 and 6 weeks after the implantation. Specimens were freeze dried, and observed by scanning electron microscope (SEM).At 3 weeks after the implantation, the bone surface of the SLA implant was relatively smooth and there were some osseous lacunae. In contrast, rough, porous bone tissue was formed in the TPS implant and the bone surface had more lacunae than the SLA implant. At 6 weeks vessels in the osseous lacunae on the bone surface of the SLA implants, were reduced, while new bone formation was not completed around the TPS implants. On image analysis, a higher bone contact ratio was noted in the SLA group (54.7% 3W, 70.8% at 6W) than the TPS group (48.3% 3W, 60.6% at 6W).These result suggests that a surface treatment for implants can accelerate the regeneration of perimplant bone and blood vessels.","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"3 1","pages":"316-324"},"PeriodicalIF":0.0,"publicationDate":"2001-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77983763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of p27Kip1 and Its Roles in Oral Squamous Cell Carcinoma p27Kip1在口腔鳞状细胞癌中的表达及其作用

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.229

Y. Kudo

引用次数: 0

Regulation of Cell Survival, Apoptosis and Differentiation by ASK 1 ASK对细胞存活、凋亡和分化的调控

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.239

K. Takeda

引用次数: 0

Dental Focal Infection Associated with Skin Diseases 与皮肤疾病相关的牙局灶感染

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.310

C. Iwai, S. Tsurusako, Y. Ohara, M. Obuchi, N. Segami

引用次数: 2

Distribution and Molecular Characterization of Porphyromonas gingivalis Carrying a New Type of fimA Gene 携带新型fimA基因的牙龈卟啉单胞菌的分布及分子特性研究

Japanese Journal of Oral Biology Pub Date : 2001-06-20 DOI: 10.2330/JORALBIOSCI1965.43.247

Ichiro Nakagawa

{"title":"Distribution and Molecular Characterization of Porphyromonas gingivalis Carrying a New Type of fimA Gene","authors":"Ichiro Nakagawa","doi":"10.2330/JORALBIOSCI1965.43.247","DOIUrl":"https://doi.org/10.2330/JORALBIOSCI1965.43.247","url":null,"abstract":"主たる口腔疾患の1つである歯周病は,病原性細菌により引き起こされる感染症的色彩の強い疾患であり,歯周病患者プラークから高頻度で分離される約10種の細菌による複合感染と考えられている。しかし,この数年間の研究手法の画期的な進歩により細菌種の高感度検出法や宿主要因の解析が可能となった結果,いくつかの細菌種はその病原性が疑問視されてきており,歯周病性菌とされるメンバーは確定したとはいまだいい難い1)。そのなかで,グラム陰性の偏性嫌気性細菌であるPorphyromonas gingivalis(以下,P. gingivalis)が,成人性歯周疾患の主たる病原性細菌であることは,世界的にも多数の研究者の支持する見解であり,本菌はさまざまなタイプの歯周疾患に密接に関与していると考えられている2-5)。一般に感染症は,病原性細菌が特有の機構を介して粘膜や皮膚等の表面に付着し,増殖を経て病巣形成部位に定着することによって発症へ向かっていく。P. gingivalisにおいても口腔内に侵入し,付着・定着することが歯周病発症の最初のステップであると考えられている。P. gingivalisは本菌の付着・定着に関与すると考えられている多くの病原因子を産生するが,そのなかでも特に線毛は,特定のヒトタンパク,単球・マクロファージ, 歯肉線維芽細胞や上皮細胞への特異的結合能を有することが数多く報告されている。また,線毛は強い免疫誘導能をもつことから,本菌の最も重要な病原因子の1つであると考えられている6-10)。","PeriodicalId":14631,"journal":{"name":"Japanese Journal of Oral Biology","volume":"70 1","pages":"247-256"},"PeriodicalIF":0.0,"publicationDate":"2001-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86112845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13